Motif ID: bHLH_family.p2

Z-value: 2.766


Transcription factors associated with bHLH_family.p2:

Gene SymbolEntrez IDGene Name
ARNTL 406 aryl hydrocarbon receptor nuclear translocator-like
ARNTL2 56938 aryl hydrocarbon receptor nuclear translocator-like 2
CLOCK 9575 clock homolog (mouse)
HES6 55502 hairy and enhancer of split 6 (Drosophila)
HEY1 23462 hairy/enhancer-of-split related with YRPW motif 1
HEY2 23493 hairy/enhancer-of-split related with YRPW motif 2
HEYL 26508 hairy/enhancer-of-split related with YRPW motif-like
ID1 3397 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
MITF 4286 microphthalmia-associated transcription factor
MLXIPL 51085 MLX interacting protein-like
MNT 4335 MAX binding protein
MXD3 83463 MAX dimerization protein 3
MXD4 10608 MAX dimerization protein 4
MXI1 4601 MAX interactor 1
NPAS2 4862 neuronal PAS domain protein 2
OLIG1 116448 oligodendrocyte transcription factor 1
OLIG2 10215 oligodendrocyte lineage transcription factor 2
TFE3 7030 transcription factor binding to IGHM enhancer 3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
MITFhg19_v1_chr3_+_69812620_69812706-0.893.0e-26Click!
HES6hg19_v1_chr2_-_239148626_2391486900.805.7e-18Click!
MXI1hg19_v1_chr10_+_111969988_111969988-0.774.3e-16Click!
MXD4hg19_v1_chr4_-_2263808_2263839-0.702.8e-12Click!
MXD3hg19_v1_chr5_-_176739291_1767392910.653.1e-10Click!
ARNTLhg19_v1_chr11_+_13299349_132993670.553.6e-07Click!
HEY2hg19_v1_chr6_+_126070813_1260708720.505.4e-06Click!
ARNTL2hg19_v1_chr12_+_27485767_274859920.252.9e-02Click!
MLXIPLhg19_v1_chr7_-_73038814_73038927-0.243.6e-02Click!
ID1hg19_v1_chr20_+_30193083_30193190-0.161.8e-01Click!
MNThg19_v1_chr17_-_2304217_2304415-0.123.2e-01Click!
TFE3hg19_v1_chrX_-_48900932_48900989-0.113.5e-01Click!
NPAS2hg19_v1_chr2_+_101436491_101437041-0.094.6e-01Click!
OLIG1hg19_v1_chr21_+_34442550_34442572-0.047.1e-01Click!
HEY1hg19_v1_chr8_-_80679897_806800970.037.9e-01Click!
CLOCKhg19_v1_chr4_-_56412968_564130150.028.7e-01Click!
HEYLhg19_v1_chr1_-_40105296_401053360.019.5e-01Click!


Activity profile for motif bHLH_family.p2.

activity profile for motif bHLH_family.p2


Sorted Z-values histogram for motif bHLH_family.p2

Sorted Z-values for motif bHLH_family.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of bHLH_family.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_-_212873104 22.474 BATF3
basic leucine zipper transcription factor, ATF-like 3
chr3_-_170626425 21.730 NM_020390
EIF5A2
eukaryotic translation initiation factor 5A2
chr3_-_170626381 19.224 EIF5A2
eukaryotic translation initiation factor 5A2
chr11_-_61684981 19.125 NM_013401
RAB3IL1
RAB3A interacting protein (rabin3)-like 1
chr2_+_113403433 18.569 NM_005415
SLC20A1
solute carrier family 20 (phosphate transporter), member 1
chr13_-_20767036 17.902 GJB2
gap junction protein, beta 2, 26kDa
chr11_+_12132063 16.435 NM_014632
MICAL2
microtubule associated monoxygenase, calponin and LIM domain containing 2
chr1_-_32281577 16.115 NM_144569
SPOCD1
SPOC domain containing 1
chr19_+_10764896 16.070 NM_001137673
NM_004516
NM_012218
NM_017620
NM_153464
ILF3




interleukin enhancer binding factor 3, 90kDa




chr5_+_150827187 15.766 SLC36A1
solute carrier family 36 (proton/amino acid symporter), member 1
chr19_+_49055421 15.529 NM_177973
SULT2B1
sulfotransferase family, cytosolic, 2B, member 1
chr13_+_28494136 15.427 NM_000209
PDX1
pancreatic and duodenal homeobox 1
chr1_-_21058701 15.356 SH2D5
SH2 domain containing 5
chr12_-_58146110 15.182 CDK4
cyclin-dependent kinase 4
chr12_-_58146108 14.969 CDK4
cyclin-dependent kinase 4
chr17_-_38256548 14.710 NR1D1
nuclear receptor subfamily 1, group D, member 1
chr5_-_172755195 14.676 STC2
stanniocalcin 2
chr1_-_212873306 14.604 NM_018664
BATF3
basic leucine zipper transcription factor, ATF-like 3
chr12_-_58146025 14.408 CDK4
cyclin-dependent kinase 4
chr11_-_85780105 13.878 NM_001008660
NM_001206946
NM_007166
PICALM


phosphatidylinositol binding clathrin assembly protein


chr5_+_150827138 13.663 NM_078483
SLC36A1
solute carrier family 36 (proton/amino acid symporter), member 1
chr6_+_151646634 13.637 NM_144497
AKAP12
A kinase (PRKA) anchor protein 12
chr1_-_212873197 13.477 BATF3
basic leucine zipper transcription factor, ATF-like 3
chr19_+_10765106 13.459 ILF3
interleukin enhancer binding factor 3, 90kDa
chr9_-_131940481 13.331 IER5L
immediate early response 5-like
chr17_-_38256905 13.196 NM_021724
NR1D1
nuclear receptor subfamily 1, group D, member 1
chr5_+_150827204 12.918 SLC36A1
solute carrier family 36 (proton/amino acid symporter), member 1
chr12_-_58146118 12.815 NM_000075
CDK4
cyclin-dependent kinase 4
chr11_-_85780088 12.781 PICALM
phosphatidylinositol binding clathrin assembly protein
chr9_-_131940538 12.752 NM_203434
IER5L
immediate early response 5-like
chr19_+_10764987 12.605 ILF3
interleukin enhancer binding factor 3, 90kDa
chr1_+_239549834 12.138 CHRM3
cholinergic receptor, muscarinic 3
chr12_-_28122884 11.778 NM_198964
NM_198966
PTHLH

parathyroid hormone-like hormone

chr5_-_73937248 11.731 NM_003633
ENC1
ectodermal-neural cortex 1 (with BTB-like domain)
chr11_-_85779821 11.713 PICALM
phosphatidylinositol binding clathrin assembly protein
chr17_-_4458618 10.960 NM_001105538
NM_014520
MYBBP1A

MYB binding protein (P160) 1a

chr4_-_99850242 10.757 NM_001130678
EIF4E
eukaryotic translation initiation factor 4E
chr11_+_18344113 10.650 GTF2H1
general transcription factor IIH, polypeptide 1, 62kDa
chr8_-_75233461 10.510 NM_020647
JPH1
junctophilin 1
chr17_-_41623652 10.490 NM_001079675
ETV4
ets variant 4
chrX_+_118108575 10.468 LONRF3
LON peptidase N-terminal domain and ring finger 3
chr2_+_241375207 10.331 GPC1
glypican 1
chr4_-_99850280 10.318 EIF4E
eukaryotic translation initiation factor 4E
chrX_+_16804531 10.289 NM_001168683
NM_018360
TXLNG

taxilin gamma

chr19_-_10047014 10.280 NM_058164
OLFM2
olfactomedin 2
chr6_+_7726268 10.178 BMP6
bone morphogenetic protein 6
chr6_-_45983279 10.065 NM_016929
CLIC5
chloride intracellular channel 5
chr9_-_33473846 10.053 NOL6
nucleolar protein family 6 (RNA-associated)
chr1_+_154193294 10.012 NM_014847
UBAP2L
ubiquitin associated protein 2-like
chr9_-_33473876 10.009 NOL6
nucleolar protein family 6 (RNA-associated)
chr11_-_2018568 9.948 H19
H19, imprinted maternally expressed transcript (non-protein coding)
chr5_+_34656482 9.845 RAI14
retinoic acid induced 14
chr21_-_44299605 9.800 WDR4
WD repeat domain 4
chr5_-_172755418 9.760 STC2
stanniocalcin 2
chr11_-_2018703 9.685 H19
H19, imprinted maternally expressed transcript (non-protein coding)
chrX_+_118108595 9.648 NM_001031855
NM_024778
LONRF3

LON peptidase N-terminal domain and ring finger 3

chr8_+_22436253 9.578 NM_021630
PDLIM2
PDZ and LIM domain 2 (mystique)
chr22_-_37882214 9.460 NM_001166343
NM_002405
MFNG

MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase

chr3_+_50654558 9.416 NM_001243925
NM_004635
MAPKAPK3

mitogen-activated protein kinase-activated protein kinase 3

chr11_+_69455837 9.396 NM_053056
CCND1
cyclin D1
chr1_-_95007139 9.318 NM_001178096
NM_001993
F3

coagulation factor III (thromboplastin, tissue factor)

chr5_+_92920592 9.290 NR2F1
NR2F2
nuclear receptor subfamily 2, group F, member 1
nuclear receptor subfamily 2, group F, member 2
chrX_+_152770083 9.262 BGN
biglycan
chr9_-_140196702 9.234 NM_001004354
NRARP
NOTCH-regulated ankyrin repeat protein
chr19_-_35981345 9.228 NM_001244847
NM_207392
KRTDAP

keratinocyte differentiation-associated protein

chr9_-_33473919 9.180 NM_022917
NM_139235
NOL6

nucleolar protein family 6 (RNA-associated)

chr1_-_182573393 9.123 NM_002928
RGS16
regulator of G-protein signaling 16
chr21_+_45209398 9.116 NM_003683
RRP1
ribosomal RNA processing 1 homolog (S. cerevisiae)
chr11_-_2018446 9.037 H19
H19, imprinted maternally expressed transcript (non-protein coding)
chr13_-_20767100 9.027 NM_004004
GJB2
gap junction protein, beta 2, 26kDa
chr3_-_49967194 8.938 NM_001142501
NM_032355
MON1A

MON1 homolog A (yeast)

chr17_-_74722843 8.935 NM_001081461
NM_015167
JMJD6

jumonji domain containing 6

chr5_+_34656595 8.823 NM_001145520
RAI14
retinoic acid induced 14
chr3_+_50654600 8.778 MAPKAPK3
mitogen-activated protein kinase-activated protein kinase 3
chr21_+_45209448 8.776 RRP1
ribosomal RNA processing 1 homolog (S. cerevisiae)
chr2_+_208576365 8.655 CCNYL1
cyclin Y-like 1
chr12_+_54426831 8.654 NM_018953
HOXC5
homeobox C5
chr20_+_61273823 8.572 SLCO4A1
solute carrier organic anion transporter family, member 4A1
chr17_-_43510279 8.559 NM_174919
ARHGAP27
Rho GTPase activating protein 27
chrX_-_100603956 8.546 NM_004085
TIMM8A
translocase of inner mitochondrial membrane 8 homolog A (yeast)
chr1_-_113498615 8.524 NM_001166496
SLC16A1
solute carrier family 16, member 1 (monocarboxylic acid transporter 1)
chr12_+_50497790 8.512 NM_005276
GPD1
glycerol-3-phosphate dehydrogenase 1 (soluble)
chr3_+_50654589 8.493 MAPKAPK3
mitogen-activated protein kinase-activated protein kinase 3
chr6_-_97345747 8.440 NDUFAF4
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 4
chr17_+_5185551 8.363 NM_001083585
NM_004703
RABEP1

rabaptin, RAB GTPase binding effector protein 1

chr12_+_101673895 8.356 NM_014503
UTP20
UTP20, small subunit (SSU) processome component, homolog (yeast)
chr3_+_5021141 8.324 BHLHE40
basic helix-loop-helix family, member e40
chr8_+_120220554 8.309 NM_052886
MAL2
mal, T-cell differentiation protein 2 (gene/pseudogene)
chr3_+_5021096 8.292 NM_003670
BHLHE40
basic helix-loop-helix family, member e40
chr19_-_40854283 8.247 NM_178830
C19orf47
chromosome 19 open reading frame 47
chr5_+_110427869 8.219 NM_139281
WDR36
WD repeat domain 36
chr6_-_3227776 8.194 NM_178012
TUBB2B
tubulin, beta 2B class IIb
chr2_-_75062214 8.186


chr2_-_110873533 8.183 MALL
mal, T-cell differentiation protein-like
chr3_+_183967414 8.167 NM_014693
NM_032331
ECE2

endothelin converting enzyme 2

chr2_-_110873353 8.160 MALL
mal, T-cell differentiation protein-like
chrX_-_100603673 8.159 NM_001145951
TIMM8A
translocase of inner mitochondrial membrane 8 homolog A (yeast)
chr9_+_131709991 8.156 NUP188
nucleoporin 188kDa
chr17_+_48133331 8.098 NM_002204
NM_005501
ITGA3

integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)

chr5_+_34656367 8.098 NM_001145522
NM_015577
RAI14

retinoic acid induced 14

chr17_-_36831156 8.090 NM_001130677
C17orf96
chromosome 17 open reading frame 96
chr17_+_38119225 8.085 NM_178171
GSDMA
gasdermin A
chr4_+_81187741 8.022 NM_004464
NM_033143
FGF5

fibroblast growth factor 5

chr7_+_102074002 7.998 ORAI2
ORAI calcium release-activated calcium modulator 2
chr11_+_126081618 7.990 NM_024556
FAM118B
family with sequence similarity 118, member B
chr4_-_57522469 7.981 NM_001145459
NM_139211
HOPX

HOP homeobox

chr17_-_43510204 7.967 ARHGAP27
Rho GTPase activating protein 27
chr3_+_183967469 7.918 ECE2
endothelin converting enzyme 2
chr2_-_110873638 7.910 MALL
mal, T-cell differentiation protein-like
chr1_-_53164014 7.904 SELRC1
Sel1 repeat containing 1
chr12_+_66218141 7.886 NM_003483
NM_003484
HMGA2

high mobility group AT-hook 2

chr17_-_74722614 7.845 JMJD6
jumonji domain containing 6
chr2_-_110874142 7.843 NM_005434
MALL
mal, T-cell differentiation protein-like
chr17_-_2614926 7.832 NM_015229
KIAA0664
KIAA0664
chr1_+_218458646 7.635 RRP15
ribosomal RNA processing 15 homolog (S. cerevisiae)
chr17_-_39211462 7.611 NM_033032
KRTAP2-2
keratin associated protein 2-2
chr17_-_39093671 7.522 NM_015515
KRT23
keratin 23 (histone deacetylase inducible)
chr5_-_94620277 7.498 NM_024717
MCTP1
multiple C2 domains, transmembrane 1
chr17_+_48133357 7.473 ITGA3
integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
chr17_-_39203423 7.469 NM_001123387
KRTAP2-1
keratin associated protein 2-1
chr1_-_201346804 7.423 NM_000364
NM_001001430
NM_001001431
NM_001001432
TNNT2



troponin T type 2 (cardiac)



chr6_+_151561094 7.414 NM_005100
AKAP12
A kinase (PRKA) anchor protein 12
chr7_-_100808832 7.398 NM_003378
VGF
VGF nerve growth factor inducible
chr11_-_2018334 7.398 H19
H19, imprinted maternally expressed transcript (non-protein coding)
chr3_+_5021305 7.372 BHLHE40
basic helix-loop-helix family, member e40
chr1_+_152486977 7.342 NM_019060
CRCT1
cysteine-rich C-terminal 1
chr9_+_131709970 7.313 NM_015354
NUP188
nucleoporin 188kDa
chr12_-_123380628 7.291 VPS37B
vacuolar protein sorting 37 homolog B (S. cerevisiae)
chr17_-_38978824 7.291 NM_000421
KRT10
keratin 10
chr11_+_72929392 7.279 NM_176071
P2RY2
purinergic receptor P2Y, G-protein coupled, 2
chr2_-_220118610 7.217 NM_006000
TUBA4A
tubulin, alpha 4a
chr20_+_2633177 7.198 NM_006392
NOP56
NOP56 ribonucleoprotein homolog (yeast)
chr1_-_21059132 7.198 NM_001103160
NM_001103161
SH2D5

SH2 domain containing 5

chr6_-_47277354 7.135 TNFRSF21
tumor necrosis factor receptor superfamily, member 21
chr10_-_120514277 7.116


chr5_+_176873795 7.075 NM_001174101
NM_030567
PRR7

proline rich 7 (synaptic)

chr19_-_40854410 7.068 C19orf47
chromosome 19 open reading frame 47
chr7_+_48128939 7.042 UPP1
uridine phosphorylase 1
chr17_-_78450247 7.010 NM_002522
NPTX1
neuronal pentraxin I
chr1_+_26496382 7.008 NM_015871
ZNF593
zinc finger protein 593
chr2_+_88991166 6.991 NM_144563
RPIA
ribose 5-phosphate isomerase A
chr9_-_135545327 6.968 DDX31
DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
chr15_+_32933869 6.943 NM_001144757
NM_003020
SCG5

secretogranin V (7B2 protein)

chr1_-_201346783 6.932 TNNT2
troponin T type 2 (cardiac)
chr4_-_4291889 6.859 NM_017816
LYAR
Ly1 antibody reactive homolog (mouse)
chr16_-_103557 6.810 NM_016310
POLR3K
polymerase (RNA) III (DNA directed) polypeptide K, 12.3 kDa
chr14_-_71275732 6.788 NM_033141
MAP3K9
mitogen-activated protein kinase kinase kinase 9
chr9_-_34048887 6.772 NM_018449
UBAP2
ubiquitin associated protein 2
chr4_-_4291817 6.765 LYAR
Ly1 antibody reactive homolog (mouse)
chr11_+_18343794 6.763 NM_001142307
NM_005316
GTF2H1

general transcription factor IIH, polypeptide 1, 62kDa

chr3_-_50360109 6.746 NM_003773
NM_033158
HYAL2

hyaluronoglucosaminidase 2

chr11_+_72929606 6.746 P2RY2
purinergic receptor P2Y, G-protein coupled, 2
chr4_+_75230856 6.725 NM_001432
EREG
epiregulin
chr15_-_75932509 6.665 NM_018285
IMP3
IMP3, U3 small nucleolar ribonucleoprotein, homolog (yeast)
chr15_+_89164522 6.664 NM_022767
AEN
apoptosis enhancing nuclease
chr6_+_41889234 6.660


chr6_+_44191276 6.629 NM_001078175
NM_001078176
NM_001078177
SLC29A1


solute carrier family 29 (nucleoside transporters), member 1


chr1_-_156675237 6.628 NM_001878
NM_001199723
CRABP2

cellular retinoic acid binding protein 2

chr20_+_23331372 6.610 NM_013248
NXT1
NTF2-like export factor 1
chr9_-_34048869 6.609 UBAP2
ubiquitin associated protein 2
chr16_+_56965747 6.590 NM_001010989
NM_001010990
NM_014685
HERPUD1


homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1


chr2_-_208634051 6.543 NM_003468
FZD5
frizzled family receptor 5
chr19_-_2783332 6.533 NM_003021
SGTA
small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
chr17_-_73874056 6.477 TRIM47
tripartite motif containing 47
chr4_-_4291731 6.455 NM_001145725
LYAR
Ly1 antibody reactive homolog (mouse)
chr19_+_45909466 6.450 NM_012099
CD3EAP
CD3e molecule, epsilon associated protein
chr1_+_44440595 6.404 NM_001039457
NM_004047
ATP6V0B

ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b

chr17_-_74722629 6.396 JMJD6
jumonji domain containing 6
chr4_-_11430502 6.346 NM_005114
HS3ST1
heparan sulfate (glucosamine) 3-O-sulfotransferase 1
chr19_+_18530087 6.342 NM_001009998
NM_032627
SSBP4

single stranded DNA binding protein 4

chr2_-_130956011 6.340 NM_207312
TUBA3E
tubulin, alpha 3e
chr7_-_2354050 6.339 NM_013321
SNX8
sorting nexin 8
chr11_+_72929302 6.331 NM_002564
NM_176072
P2RY2

purinergic receptor P2Y, G-protein coupled, 2

chr1_+_44440623 6.322 ATP6V0B
ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
chr17_-_39222126 6.317 NM_033184
KRTAP2-4
keratin associated protein 2-4
chr4_-_57522059 6.310 HOPX
HOP homeobox
chr11_-_64645925 6.259 EHD1
EH-domain containing 1
chr11_+_67159421 6.253 NM_004584
RAD9A
RAD9 homolog A (S. pombe)
chr8_+_67341244 6.251 NM_015169
RRS1
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
chr19_+_45909868 6.235 CD3EAP
CD3e molecule, epsilon associated protein
chr20_+_39657461 6.211 NM_003286
TOP1
topoisomerase (DNA) I
chr11_+_45944155 6.196 GYLTL1B
glycosyltransferase-like 1B
chr11_+_120081669 6.168 NM_178507
OAF
OAF homolog (Drosophila)
chr7_-_105162551 6.163 NM_019042
PUS7
pseudouridylate synthase 7 homolog (S. cerevisiae)
chr7_-_124405029 6.160 GPR37
G protein-coupled receptor 37 (endothelin receptor type B-like)
chr11_-_65667860 6.152 NM_005438
FOSL1
FOS-like antigen 1
chr8_+_22436641 6.145 PDLIM2
PDZ and LIM domain 2 (mystique)
chr13_-_50699775 6.131 DLEU2
deleted in lymphocytic leukemia 2 (non-protein coding)
chr21_-_44299660 6.114 NM_018669
NM_033661
WDR4

WD repeat domain 4

chr10_-_82049178 6.107 NM_000429
MAT1A
methionine adenosyltransferase I, alpha
chr6_+_151561508 6.080 AKAP12
A kinase (PRKA) anchor protein 12
chr11_-_64646053 6.055 NM_006795
EHD1
EH-domain containing 1
chr19_-_1237840 6.048 NM_152769
C19orf26
chromosome 19 open reading frame 26
chr8_+_145582208 6.044 NM_001253816
NM_001253815
GPR172A

G protein-coupled receptor 172A

chr3_+_183967514 6.037 ECE2
endothelin converting enzyme 2
chr6_+_31783314 6.036 HSPA1A
HSPA1B
heat shock 70kDa protein 1A
heat shock 70kDa protein 1B
chr17_+_40719064 6.021 NM_170607
NM_198204
NM_198205
MLX


MAX-like protein X


chr13_+_37005966 5.985 NM_001111046
NM_001111047
CCNA1

cyclin A1

chr6_+_31795395 5.945 NM_005346
HSPA1A
HSPA1B
heat shock 70kDa protein 1A
heat shock 70kDa protein 1B
chr6_-_47277640 5.926 TNFRSF21
tumor necrosis factor receptor superfamily, member 21

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
4.10 1.42e-12 GO:0042254 ribosome biogenesis
1.63 5.61e-11 GO:0010467 gene expression
3.16 3.39e-10 GO:0022613 ribonucleoprotein complex biogenesis
3.06 7.63e-10 GO:0071843 cellular component biogenesis at cellular level
2.05 6.54e-09 GO:0006396 RNA processing
2.69 6.89e-09 GO:0034660 ncRNA metabolic process
3.05 7.23e-09 GO:0034470 ncRNA processing
1.59 8.58e-09 GO:0016070 RNA metabolic process
1.44 2.72e-08 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.39 3.37e-08 GO:0006807 nitrogen compound metabolic process
1.40 4.49e-08 GO:0034641 cellular nitrogen compound metabolic process
1.13 2.64e-07 GO:0009987 cellular process
3.69 9.18e-07 GO:0016072 rRNA metabolic process
1.46 9.83e-07 GO:0090304 nucleic acid metabolic process
3.63 5.56e-06 GO:0006364 rRNA processing
1.28 6.75e-06 GO:0044260 cellular macromolecule metabolic process
1.60 2.35e-05 GO:0044085 cellular component biogenesis
1.20 9.96e-05 GO:0044238 primary metabolic process
1.20 1.18e-04 GO:0044237 cellular metabolic process
1.23 1.67e-04 GO:0043170 macromolecule metabolic process
1.17 5.12e-04 GO:0008152 metabolic process
2.51 1.36e-02 GO:0007005 mitochondrion organization
1.58 1.68e-02 GO:0046907 intracellular transport
8.86 2.51e-02 GO:0007007 inner mitochondrial membrane organization
1.28 3.05e-02 GO:0071841 cellular component organization or biogenesis at cellular level
1.52 4.32e-02 GO:0045184 establishment of protein localization
1.25 4.52e-02 GO:0051234 establishment of localization
1.23 4.76e-02 GO:0071840 cellular component organization or biogenesis

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
2.72 3.94e-20 GO:0005730 nucleolus
1.16 5.37e-17 GO:0005622 intracellular
1.17 2.25e-16 GO:0044424 intracellular part
1.62 5.91e-16 GO:0031974 membrane-enclosed lumen
1.71 1.15e-15 GO:0031981 nuclear lumen
1.64 3.22e-15 GO:0044428 nuclear part
1.60 1.78e-14 GO:0043233 organelle lumen
1.60 2.63e-14 GO:0070013 intracellular organelle lumen
1.32 3.65e-13 GO:0044446 intracellular organelle part
1.31 5.35e-13 GO:0044422 organelle part
1.18 6.17e-12 GO:0043229 intracellular organelle
1.18 7.09e-12 GO:0043226 organelle
1.28 5.26e-10 GO:0005634 nucleus
1.43 4.07e-09 GO:0043228 non-membrane-bounded organelle
1.43 4.07e-09 GO:0043232 intracellular non-membrane-bounded organelle
1.18 6.85e-09 GO:0043231 intracellular membrane-bounded organelle
1.17 9.12e-09 GO:0043227 membrane-bounded organelle
7.09 4.90e-08 GO:0044452 nucleolar part
1.18 6.35e-08 GO:0005737 cytoplasm
1.53 1.21e-05 GO:0005654 nucleoplasm
1.34 9.34e-04 GO:0005829 cytosol
3.25 1.26e-03 GO:0005643 nuclear pore
2.99 1.71e-03 GO:0046930 pore complex
6.75 2.10e-03 GO:0030684 preribosome
1.17 2.49e-03 GO:0044444 cytoplasmic part
7.52 3.21e-03 GO:0005732 small nucleolar ribonucleoprotein complex
1.69 4.23e-03 GO:0030529 ribonucleoprotein complex
1.05 6.37e-03 GO:0044464 cell part
1.05 6.56e-03 GO:0005623 cell
1.56 9.06e-03 GO:0031967 organelle envelope
9.85 1.03e-02 GO:0042719 mitochondrial intermembrane space protein transporter complex
1.21 1.70e-02 GO:0032991 macromolecular complex
1.53 1.76e-02 GO:0031975 envelope
11.82 2.18e-02 GO:0031428 box C/D snoRNP complex
6.45 4.96e-02 GO:0005744 mitochondrial inner membrane presequence translocase complex

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
1.24 3.39e-11 GO:0005515 protein binding
1.10 5.19e-06 GO:0005488 binding
1.70 1.19e-05 GO:0003723 RNA binding
1.23 1.20e-02 GO:0003676 nucleic acid binding
1.33 2.66e-02 GO:0016740 transferase activity
4.62 4.23e-02 GO:0016796 exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters