Motif ID: ZNF423.p2

Z-value: 1.012


Transcription factors associated with ZNF423.p2:

Gene SymbolEntrez IDGene Name
ZNF423 23090 zinc finger protein 423

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
ZNF423hg19_v1_chr16_-_49860917_49860917-0.123.1e-01Click!


Activity profile for motif ZNF423.p2.

activity profile for motif ZNF423.p2


Sorted Z-values histogram for motif ZNF423.p2

Sorted Z-values for motif ZNF423.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ZNF423.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_+_74735107 11.113 NM_001511
CXCL1
chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
chr20_+_44098392 5.251 NM_006103
WFDC2
WAP four-disulfide core domain 2
chr8_-_133493003 5.133 NM_004519
KCNQ3
potassium voltage-gated channel, KQT-like subfamily, member 3
chr8_-_133492556 4.441 KCNQ3
potassium voltage-gated channel, KQT-like subfamily, member 3
chr4_-_74964836 4.401 CXCL2
chemokine (C-X-C motif) ligand 2
chr2_-_216245573 4.292 FN1
fibronectin 1
chr20_+_36531548 4.272 VSTM2L
V-set and transmembrane domain containing 2 like
chr10_+_17271276 4.062 VIM
vimentin
chr10_+_17271277 3.952 VIM
vimentin
chr10_+_17271341 3.937 VIM
vimentin
chr8_-_133492751 3.836 KCNQ3
potassium voltage-gated channel, KQT-like subfamily, member 3
chr20_+_36531498 3.799 NM_080607
VSTM2L
V-set and transmembrane domain containing 2 like
chr10_+_17271302 3.641 VIM
vimentin
chr10_+_99079017 3.230 NM_005479
FRAT1
frequently rearranged in advanced T-cell lymphomas
chr19_+_14544100 3.124 NM_002741
PKN1
protein kinase N1
chr4_+_57371374 2.859 NM_206919
ARL9
ADP-ribosylation factor-like 9
chr4_-_74904329 2.827 NM_002090
CXCL3
chemokine (C-X-C motif) ligand 3
chr11_+_46403279 2.572 MDK
midkine (neurite growth-promoting factor 2)
chrX_-_19140581 2.474 NM_001079858
NM_001079859
NM_001079860
NM_001184833
NM_001184834
NM_001184835
NM_001184836
NM_001184837
NM_005756
GPR64








G protein-coupled receptor 64








chr7_-_142985270 2.447


chr2_-_145274916 2.404 ZEB2
zinc finger E-box binding homeobox 2
chr20_-_62130390 2.325 NM_001958
EEF1A2
eukaryotic translation elongation factor 1 alpha 2
chr11_+_46403302 2.306 NM_001012333
MDK
midkine (neurite growth-promoting factor 2)
chr19_+_14544216 2.133 PKN1
protein kinase N1
chr3_-_127541975 2.115 NM_001003794
MGLL
monoglyceride lipase
chr10_-_95360959 2.106 NM_006744
RBP4
retinol binding protein 4, plasma
chr5_-_1112106 1.988 NM_006598
SLC12A7
solute carrier family 12 (potassium/chloride transporters), member 7
chrX_-_51239295 1.814 NUDT11
nudix (nucleoside diphosphate linked moiety X)-type motif 11
chrX_-_51239426 1.796 NM_018159
NUDT11
nudix (nucleoside diphosphate linked moiety X)-type motif 11
chr5_+_150400132 1.705 GPX3
glutathione peroxidase 3 (plasma)
chr10_-_135090325 1.668 NM_001109
NM_001164489
NM_001164490
ADAM8


ADAM metallopeptidase domain 8


chr19_-_19932512 1.623 NM_001099269
NM_001145404
ZNF506

zinc finger protein 506

chr17_+_77020229 1.613 NM_030968
NM_198594
C1QTNF1

C1q and tumor necrosis factor related protein 1

chr5_+_150399980 1.595 NM_002084
GPX3
glutathione peroxidase 3 (plasma)
chr3_-_16555128 1.583 NM_015150
RFTN1
raftlin, lipid raft linker 1
chr17_+_39969205 1.571 FKBP10
FK506 binding protein 10, 65 kDa
chr21_+_47531369 1.562 COL6A2
collagen, type VI, alpha 2
chr16_-_325867 1.549 NM_003834
NM_183337
RGS11

regulator of G-protein signaling 11

chr7_+_100081549 1.510 NM_173564
NYAP1
neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 1
chr2_-_145275086 1.493 ZEB2
zinc finger E-box binding homeobox 2
chr4_-_141348760 1.489 NM_001130675
NM_004362
CLGN

calmegin

chr5_+_176784947 1.480


chr1_+_47489239 1.457 NM_178033
CYP4X1
cytochrome P450, family 4, subfamily X, polypeptide 1
chr10_+_17270469 1.455 VIM
vimentin
chr17_+_39969200 1.439 FKBP10
FK506 binding protein 10, 65 kDa
chr5_+_92920592 1.425 NR2F1
NR2F2
nuclear receptor subfamily 2, group F, member 1
nuclear receptor subfamily 2, group F, member 2
chr8_-_11324184 1.414 NM_053279
FAM167A
family with sequence similarity 167, member A
chrX_-_107019001 1.397 NM_198057
TSC22D3
TSC22 domain family, member 3
chr3_-_16554992 1.376 RFTN1
raftlin, lipid raft linker 1
chr1_-_40254131 1.344 BMP8B
bone morphogenetic protein 8b
chr6_+_33244916 1.327 NM_003782
B3GALT4
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
chr14_-_23822025 1.304 NM_016609
SLC22A17
solute carrier family 22, member 17
chr2_+_121554866 1.295 NM_005270
GLI2
GLI family zinc finger 2
chr16_+_67679011 1.288 NM_001013838
RLTPR
RGD motif, leucine rich repeats, tropomodulin domain and proline-rich containing
chr7_-_27192201 1.274


chr7_+_76139744 1.260 NM_030570
NM_182684
UPK3B

uroplakin 3B

chr8_+_145065366 1.238 GRINA
glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
chr4_+_39046198 1.233 NM_001007075
NM_001171654
KLHL5

kelch-like 5 (Drosophila)

chr17_-_76921453 1.229 NM_003255
TIMP2
TIMP metallopeptidase inhibitor 2
chr3_-_127541160 1.212 NM_007283
MGLL
monoglyceride lipase
chr9_+_116918230 1.211 NM_032888
COL27A1
collagen, type XXVII, alpha 1
chr6_-_109761707 1.164 PPIL6
peptidylprolyl isomerase (cyclophilin)-like 6
chr9_+_135037333 1.159 NM_032536
NTNG2
netrin G2
chr1_+_27719151 1.148 NM_005281
GPR3
G protein-coupled receptor 3
chr9_+_136243226 1.144 NM_153710
C9orf96
chromosome 9 open reading frame 96
chr17_+_77020278 1.139 C1QTNF1
C1q and tumor necrosis factor related protein 1
chr11_+_46403260 1.134 MDK
midkine (neurite growth-promoting factor 2)
chr10_+_99344421 1.125 HOGA1
4-hydroxy-2-oxoglutarate aldolase 1
chr19_+_45971249 1.115 NM_001114171
NM_006732
FOSB

FBJ murine osteosarcoma viral oncogene homolog B

chr19_+_36347809 1.093 NM_032123
NM_199179
NM_199180
KIRREL2


kin of IRRE like 2 (Drosophila)


chr1_+_20915440 1.080 NM_001785
CDA
cytidine deaminase
chr9_+_116638544 1.072 NM_133374
ZNF618
zinc finger protein 618
chr11_+_844111 1.051 TSPAN4
tetraspanin 4
chr1_-_212873197 1.050 BATF3
basic leucine zipper transcription factor, ATF-like 3
chr6_+_31543340 1.018 NM_000594
TNF
tumor necrosis factor
chr5_-_149681935 1.005 ARSI
arylsulfatase family, member I
chr12_-_50100966 0.987


chr1_-_228463727 0.975


chr20_+_62184372 0.972 NM_024059
C20orf195
chromosome 20 open reading frame 195
chr6_-_32160289 0.971 GPSM3
G-protein signaling modulator 3
chr15_-_35087748 0.969 NM_005159
ACTC1
actin, alpha, cardiac muscle 1
chr17_+_7608413 0.941 NM_001406
EFNB3
ephrin-B3
chr11_+_73019315 0.939 ARHGEF17
Rho guanine nucleotide exchange factor (GEF) 17
chr8_+_17433941 0.935 NM_006207
PDGFRL
platelet-derived growth factor receptor-like
chr12_+_58003962 0.917 NM_001111270
ARHGEF25
Rho guanine nucleotide exchange factor (GEF) 25
chr22_+_31003069 0.905 NM_000355
NM_001184726
TCN2

transcobalamin II

chr2_+_74776146 0.904 NM_001197260
DOK1
docking protein 1, 62kDa (downstream of tyrosine kinase 1)
chr4_-_169401603 0.904 NM_001012967
DDX60L
DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like
chr8_-_13133956 0.903


chr12_+_54410641 0.901 NM_014620
NM_153693
HOXC4
HOXC6
homeobox C4
homeobox C6
chr16_-_19896105 0.900 NM_016235
GPRC5B
G protein-coupled receptor, family C, group 5, member B
chr17_-_76921205 0.898 TIMP2
TIMP metallopeptidase inhibitor 2
chr19_+_20011700 0.884 NM_031218
ZNF93
zinc finger protein 93
chr2_-_152118258 0.874 NM_198557
RBM43
RNA binding motif protein 43
chr2_+_62932786 0.872 NM_001142616
NM_015252
EHBP1

EH domain binding protein 1

chr16_+_3014216 0.864 NM_001253725
NM_001253726
NM_024507
NM_172229
KREMEN2



kringle containing transmembrane protein 2



chr5_+_176784843 0.861 NM_006480
RGS14
regulator of G-protein signaling 14
chr10_-_62703822 0.853 NM_001242359
NM_014836
RHOBTB1

Rho-related BTB domain containing 1

chr10_+_135192694 0.841 NM_152911
NM_207127
NM_207128
PAOX


polyamine oxidase (exo-N4-amino)


chr7_-_30029284 0.836 NM_001145515
NM_014766
NM_001145513
SCRN1


secernin 1


chr19_+_7600632 0.830 PNPLA6
patatin-like phospholipase domain containing 6
chr2_-_20212408 0.826 MATN3
matrilin 3
chr17_-_79212775 0.825 C17orf56
chromosome 17 open reading frame 56
chr4_-_74964996 0.818 NM_002089
CXCL2
chemokine (C-X-C motif) ligand 2
chr14_-_103995336 0.813


chr1_+_113051369 0.810 NM_024494
WNT2B
wingless-type MMTV integration site family, member 2B
chr2_+_14772809 0.808 NM_145175
FAM84A
family with sequence similarity 84, member A
chr14_+_24837225 0.805 NM_001198965
NM_004554
NFATC4

nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4

chr21_-_44496423 0.800 NM_001178008
NM_001178009
CBS

cystathionine-beta-synthase

chr17_+_80190107 0.794 NM_001042423
SLC16A3
solute carrier family 16, member 3 (monocarboxylic acid transporter 4)
chr22_-_37823503 0.794 NM_052906
ELFN2
extracellular leucine-rich repeat and fibronectin type III domain containing 2
chr6_-_32160637 0.786 GPSM3
G-protein signaling modulator 3
chr22_-_24640850 0.783 NM_001099781
NM_001099782
NM_004121
GGT5


gamma-glutamyltransferase 5


chr19_+_47523045 0.780 NPAS1
neuronal PAS domain protein 1
chr19_+_17858504 0.769 NM_001161357
NM_001161358
FCHO1

FCH domain only 1

chr14_-_60097314 0.768 RTN1
reticulon 1
chr1_-_204120909 0.767 ETNK2
ethanolamine kinase 2
chr17_+_7462064 0.767 TNFSF13
tumor necrosis factor (ligand) superfamily, member 13
chr19_-_49314177 0.766 NM_001164773
NM_001190
BCAT2

branched chain amino-acid transaminase 2, mitochondrial

chr2_+_88469813 0.761 NM_001244676
NM_001244678
THNSL2

threonine synthase-like 2 (S. cerevisiae)

chr1_-_204121144 0.760 NM_018208
ETNK2
ethanolamine kinase 2
chr3_+_101568325 0.758 NM_031419
NFKBIZ
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta
chr3_+_52567983 0.757


chr10_-_21785873 0.756 C10orf114
chromosome 10 open reading frame 114
chr16_+_2867163 0.754 NM_006799
NM_144956
NM_144957
PRSS21


protease, serine, 21 (testisin)


chr3_+_196729776 0.741 MFI2-AS1
MFI2 antisense RNA 1 (non-protein coding)
chr4_-_103940842 0.740 NM_001100874
NM_139173
SLC9B1

solute carrier family 9, subfamily B (cation proton antiporter 2), member 1

chr9_-_133814422 0.733 NM_001145106
FIBCD1
fibrinogen C domain containing 1
chr17_+_7311501 0.732 NM_020795
NLGN2
neuroligin 2
chr11_+_844062 0.732 NM_001025234
TSPAN4
tetraspanin 4
chrX_-_107018889 0.731 TSC22D3
TSC22 domain family, member 3
chr7_-_107880492 0.730 NM_001037132
NRCAM
neuronal cell adhesion molecule
chr12_+_1726221 0.730 NM_030775
WNT5B
wingless-type MMTV integration site family, member 5B
chr12_+_111471827 0.724 NM_015267
CUX2
cut-like homeobox 2
chr9_-_131486371 0.714 NM_032799
ZDHHC12
zinc finger, DHHC-type containing 12
chr3_+_52529370 0.713 STAB1
stabilin 1
chr19_-_20748540 0.704 NM_001159293
ZNF737
zinc finger protein 737
chr2_-_20212448 0.700 NM_002381
MATN3
matrilin 3
chr19_+_36024313 0.693 NM_014364
GAPDHS
glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
chr4_+_20255234 0.692 NM_004787
SLIT2
slit homolog 2 (Drosophila)
chr12_+_54410893 0.688 HOXC5
HOXC6
homeobox C5
homeobox C6
chr6_-_109762373 0.677 NM_001111298
NM_173672
PPIL6

peptidylprolyl isomerase (cyclophilin)-like 6

chr8_+_19170999 0.673 NM_001174160
NM_022071
NM_001174159
SH2D4A


SH2 domain containing 4A


chr8_+_17013799 0.673 NM_016353
ZDHHC2
zinc finger, DHHC-type containing 2
chr4_+_84457390 0.671 NM_032717
AGPAT9
1-acylglycerol-3-phosphate O-acyltransferase 9
chr4_-_75719686 0.666 NM_001729
BTC
betacellulin
chr1_-_32707198 0.664 MTMR9LP
myotubularin related protein 9-like, pseudogene
chr7_-_151329153 0.657 NM_024429
PRKAG2
protein kinase, AMP-activated, gamma 2 non-catalytic subunit
chr3_+_52273247 0.653


chr12_-_50101127 0.651 FMNL3
formin-like 3
chr8_+_17013459 0.651 ZDHHC2
zinc finger, DHHC-type containing 2
chr17_+_1619816 0.650 NM_001163673
NM_152348
WDR81

WD repeat domain 81

chr16_+_67679058 0.649 RLTPR
RGD motif, leucine rich repeats, tropomodulin domain and proline-rich containing
chr2_+_189157551 0.645 GULP1
GULP, engulfment adaptor PTB domain containing 1
chr19_+_11909360 0.637 NM_152356
ZNF491
zinc finger protein 491
chr10_-_62761197 0.635 RHOBTB1
Rho-related BTB domain containing 1
chr6_+_89791510 0.634 PNRC1
proline-rich nuclear receptor coactivator 1
chr17_-_19651586 0.632 NM_000691
ALDH3A1
aldehyde dehydrogenase 3 family, member A1
chr4_-_44450509 0.631 KCTD8
potassium channel tetramerisation domain containing 8
chr1_+_109642814 0.631 SCARNA2
small Cajal body-specific RNA 2
chr2_+_37571752 0.628 NM_012413
QPCT
glutaminyl-peptide cyclotransferase
chr1_+_110230417 0.622 NM_000561
NM_146421
GSTM1

glutathione S-transferase mu 1

chr2_+_26785456 0.621 NM_001105519
C2orf70
chromosome 2 open reading frame 70
chr19_-_4103200 0.620 MAP2K2
mitogen-activated protein kinase kinase 2
chr8_+_17014006 0.613 ZDHHC2
zinc finger, DHHC-type containing 2
chr17_-_27229922 0.612 NM_144683
DHRS13
dehydrogenase/reductase (SDR family) member 13
chr1_-_51787881 0.612 NM_001080494
TTC39A
tetratricopeptide repeat domain 39A
chr9_-_139890984 0.609 NM_004669
CLIC3
chloride intracellular channel 3
chr2_-_224903933 0.609 NM_001136528
NM_006216
SERPINE2

serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2

chr19_+_38880839 0.603 NM_001039616
NM_001042522
SPRED3

sprouty-related, EVH1 domain containing 3

chr19_-_38806546 0.602 NM_001039672
NM_001039673
NM_001145463
YIF1B


Yip1 interacting factor homolog B (S. cerevisiae)


chr2_+_14772839 0.600 FAM84A
family with sequence similarity 84, member A
chr19_+_45174723 0.594 NM_001127893
NM_020219
CEACAM19

carcinoembryonic antigen-related cell adhesion molecule 19

chr20_+_42544781 0.590 NM_001098796
NM_032883
TOX2

TOX high mobility group box family member 2

chr6_+_151561653 0.589 AKAP12
A kinase (PRKA) anchor protein 12
chr9_-_98269480 0.586 NM_001083607
PTCH1
patched 1
chr1_-_6546013 0.584 NM_001042665
PLEKHG5
pleckstrin homology domain containing, family G (with RhoGef domain) member 5
chr17_-_79633604 0.583 NM_001039842
C17orf90
chromosome 17 open reading frame 90
chr2_-_160919120 0.581 NM_001007267
NM_001195641
NM_007366
PLA2R1


phospholipase A2 receptor 1, 180kDa


chr19_+_18391252 0.580


chr7_-_27702357 0.580 HIBADH
3-hydroxyisobutyrate dehydrogenase
chr6_-_2840683 0.567 SERPINB1
serpin peptidase inhibitor, clade B (ovalbumin), member 1
chr17_-_79633629 0.564 C17orf90
chromosome 17 open reading frame 90
chr15_-_43212911 0.562 NM_173500
TTBK2
tau tubulin kinase 2
chr3_-_158450205 0.562 RARRES1
retinoic acid receptor responder (tazarotene induced) 1
chr17_-_1029059 0.560 ABR
active BCR-related gene
chr8_-_80679897 0.560 NM_001040708
NM_012258
HEY1

hairy/enhancer-of-split related with YRPW motif 1

chr19_+_10531128 0.559 NM_001111307
PDE4A
phosphodiesterase 4A, cAMP-specific
chr21_-_46340776 0.558 ITGB2
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr11_-_119187811 0.548 NM_006500
MCAM
melanoma cell adhesion molecule
chr3_-_195808997 0.544 NM_001128148
TFRC
transferrin receptor (p90, CD71)
chr1_-_212873306 0.544 NM_018664
BATF3
basic leucine zipper transcription factor, ATF-like 3
chr7_+_30174343 0.544 NM_152793
C7orf41
chromosome 7 open reading frame 41
chr7_-_150754979 0.542 NM_001164410
NM_004935
CDK5

cyclin-dependent kinase 5

chrX_+_152908819 0.540 DUSP9
dual specificity phosphatase 9
chr11_-_6440288 0.537 NM_001164
APBB1
amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
chr6_+_42897184 0.536 CNPY3
canopy 3 homolog (zebrafish)
chr3_-_195808980 0.529 TFRC
transferrin receptor (p90, CD71)
chr19_+_45582469 0.528 NM_001007270
NM_001007269
NM_024707
GEMIN7


gem (nuclear organelle) associated protein 7


chr10_-_21786186 0.528 C10orf114
chromosome 10 open reading frame 114

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
4.85 1.86e-03 GO:0040011 locomotion
8.25 8.76e-03 GO:0006954 inflammatory response

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
4.22 4.39e-04 GO:0044421 extracellular region part
4.64 1.06e-03 GO:0005615 extracellular space
2.64 1.11e-02 GO:0005576 extracellular region

Nothing significant found in function category.