Motif ID: ZNF148.p2

Z-value: 1.645


Transcription factors associated with ZNF148.p2:

Gene SymbolEntrez IDGene Name
ZNF148 7707 zinc finger protein 148

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
ZNF148hg19_v1_chr3_-_125094003_1250941970.217.0e-02Click!


Activity profile for motif ZNF148.p2.

activity profile for motif ZNF148.p2


Sorted Z-values histogram for motif ZNF148.p2

Sorted Z-values for motif ZNF148.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ZNF148.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_+_128470462 14.431 NM_001127487
NM_001458
FLNC

filamin C, gamma

chr5_+_52776263 12.640 NM_006350
NM_013409
FST

follistatin

chr5_+_52776479 10.802 FST
follistatin
chr2_+_37571752 10.485 NM_012413
QPCT
glutaminyl-peptide cyclotransferase
chr20_-_62284701 10.472 NM_015894
STMN3
stathmin-like 3
chr22_-_20137430 9.989 NM_001243537
LOC388849
uncharacterized LOC388849
chr1_+_35225341 8.402 NM_153212
GJB4
gap junction protein, beta 4, 30.3kDa
chr4_+_81187741 8.310 NM_004464
NM_033143
FGF5

fibroblast growth factor 5

chr5_+_52776408 7.827 FST
follistatin
chr16_+_30194925 7.149 CORO1A
coronin, actin binding protein, 1A
chr10_-_30348433 7.071 NM_020848
KIAA1462
KIAA1462
chr20_+_33146500 6.915 NM_032514
MAP1LC3A
microtubule-associated protein 1 light chain 3 alpha
chr19_-_1237840 6.699 NM_152769
C19orf26
chromosome 19 open reading frame 26
chr16_+_30194730 6.590 NM_001193333
NM_007074
CORO1A

coronin, actin binding protein, 1A

chr4_-_57976516 6.574 IGFBP7
insulin-like growth factor binding protein 7
chr4_-_57976550 6.461 NM_001253835
NM_001553
IGFBP7

insulin-like growth factor binding protein 7

chr6_+_144471631 6.188 NM_003764
STX11
syntaxin 11
chr5_+_156887204 6.132 NIPAL4
NIPA-like domain containing 4
chr12_+_58005217 5.921 NM_182947
ARHGEF25
Rho guanine nucleotide exchange factor (GEF) 25
chr3_-_127541160 5.911 NM_007283
MGLL
monoglyceride lipase
chr20_+_44098392 5.910 NM_006103
WFDC2
WAP four-disulfide core domain 2
chr17_+_74380676 5.715 NM_001142601
NM_021972
NM_182965
SPHK1


sphingosine kinase 1


chr1_-_20812271 5.613 CAMK2N1
calcium/calmodulin-dependent protein kinase II inhibitor 1
chr11_-_119187811 5.600 NM_006500
MCAM
melanoma cell adhesion molecule
chr5_+_156887026 5.333 NM_001099287
NM_001172292
NIPAL4

NIPA-like domain containing 4

chr1_+_1370902 5.183 NM_022834
NM_199121
VWA1

von Willebrand factor A domain containing 1

chr12_+_66218141 5.167 NM_003483
NM_003484
HMGA2

high mobility group AT-hook 2

chr22_+_31090792 5.152 NM_030758
OSBP2
oxysterol binding protein 2
chr15_-_45422056 5.141 NM_144565
DUOXA1
dual oxidase maturation factor 1
chr1_-_95007139 5.105 NM_001178096
NM_001993
F3

coagulation factor III (thromboplastin, tissue factor)

chr19_+_48828820 5.014 EMP3
epithelial membrane protein 3
chr12_-_30907447 4.995 NM_001002259
NM_001206856
NM_023925
NM_032156
CAPRIN2



caprin family member 2



chr9_+_74764266 4.966 NM_001242505
NM_001242506
NM_004293
GDA


guanine deaminase


chr16_+_69141442 4.834 NM_005329
HAS3
hyaluronan synthase 3
chr6_+_151646634 4.745 NM_144497
AKAP12
A kinase (PRKA) anchor protein 12
chr8_+_32405727 4.716 NM_001160002
NM_001160004
NM_001160005
NM_001160007
NM_001160008
NM_004495
NM_013956
NM_013957
NM_013958
NM_013960
NM_013964
NRG1










neuregulin 1










chr5_+_71403040 4.706 NM_005909
MAP1B
microtubule-associated protein 1B
chr3_-_27764197 4.685 EOMES
eomesodermin
chr4_-_57976355 4.554 IGFBP7
insulin-like growth factor binding protein 7
chr11_+_46402333 4.553 NM_001012334
MDK
midkine (neurite growth-promoting factor 2)
chr19_-_1401474 4.444 NM_000156
NM_138924
GAMT

guanidinoacetate N-methyltransferase

chr20_-_22564893 4.440 FOXA2
forkhead box A2
chr12_+_132312917 4.403 NM_016155
MMP17
matrix metallopeptidase 17 (membrane-inserted)
chr12_+_57998600 4.357 NM_178502
DTX3
deltex homolog 3 (Drosophila)
chr20_-_62130390 4.166 NM_001958
EEF1A2
eukaryotic translation elongation factor 1 alpha 2
chr17_+_2699731 4.148 NM_001100398
NM_015085
RAP1GAP2

RAP1 GTPase activating protein 2

chr22_-_37915209 4.030 NM_014550
CARD10
caspase recruitment domain family, member 10
chrX_+_102632108 3.960 NM_014380
NGFRAP1
nerve growth factor receptor (TNFRSF16) associated protein 1
chr5_+_89770680 3.948 NM_006467
POLR3G
polymerase (RNA) III (DNA directed) polypeptide G (32kD)
chr16_-_325867 3.925 NM_003834
NM_183337
RGS11

regulator of G-protein signaling 11

chr8_+_25042066 3.911 DOCK5
dedicator of cytokinesis 5
chr19_-_409169 3.910 NM_001136263
C2CD4C
C2 calcium-dependent domain containing 4C
chr5_-_1112106 3.907 NM_006598
SLC12A7
solute carrier family 12 (potassium/chloride transporters), member 7
chr3_+_71803200 3.900 NM_018971
GPR27
G protein-coupled receptor 27
chr7_+_73703704 3.870 NM_003388
NM_032421
CLIP2

CAP-GLY domain containing linker protein 2

chr3_-_183543295 3.869 NM_024871
MAP6D1
MAP6 domain containing 1
chr13_+_24734788 3.849 NM_001166271
NM_153023
SPATA13

spermatogenesis associated 13

chr17_+_38171613 3.825 NM_000759
NM_001178147
NM_172219
NM_172220
CSF3



colony stimulating factor 3 (granulocyte)



chr14_+_90528107 3.793 NM_022054
KCNK13
potassium channel, subfamily K, member 13
chr1_-_95392501 3.771 NM_001839
CNN3
calponin 3, acidic
chr1_+_901876 3.737 NM_001160184
NM_032129
PLEKHN1

pleckstrin homology domain containing, family N member 1

chr5_+_52284903 3.706 NM_002203
ITGA2
integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
chr1_+_101702304 3.691 NM_001400
S1PR1
sphingosine-1-phosphate receptor 1
chr3_-_16555128 3.674 NM_015150
RFTN1
raftlin, lipid raft linker 1
chr20_-_56285576 3.650 NM_199169
NM_199170
PMEPA1

prostate transmembrane protein, androgen induced 1

chr3_-_16554992 3.632 RFTN1
raftlin, lipid raft linker 1
chr17_+_74380943 3.623 SPHK1
sphingosine kinase 1
chr1_-_212873104 3.617 BATF3
basic leucine zipper transcription factor, ATF-like 3
chr11_+_69455978 3.599 CCND1
cyclin D1
chr14_+_51026853 3.582 ATL1
atlastin GTPase 1
chr6_+_151561653 3.545 AKAP12
A kinase (PRKA) anchor protein 12
chr3_-_127541975 3.544 NM_001003794
MGLL
monoglyceride lipase
chr22_+_31477231 3.495 NM_006932
NM_134269
NM_134270
SMTN


smoothelin


chr2_+_182321933 3.474 ITGA4
integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
chr1_-_212873197 3.463 BATF3
basic leucine zipper transcription factor, ATF-like 3
chr15_-_40600118 3.442 NM_004573
PLCB2
phospholipase C, beta 2
chr1_-_212873306 3.437 NM_018664
BATF3
basic leucine zipper transcription factor, ATF-like 3
chr6_-_89827605 3.436 NM_080743
SRSF12
serine/arginine-rich splicing factor 12
chr18_+_12308236 3.427 TUBB6
tubulin, beta 6 class V
chrX_-_48693934 3.420 NM_013271
PCSK1N
proprotein convertase subtilisin/kexin type 1 inhibitor
chr1_-_153013593 3.416 NM_006945
SPRR2D
small proline-rich protein 2D
chr11_-_77734285 3.379 NM_023930
KCTD14
potassium channel tetramerisation domain containing 14
chr11_-_67141647 3.378 NM_001166212
CLCF1
cardiotrophin-like cytokine factor 1
chr20_+_36531548 3.362 VSTM2L
V-set and transmembrane domain containing 2 like
chr4_-_775586 3.353 LOC100129917
uncharacterized LOC100129917
chr2_+_182322265 3.316 ITGA4
integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
chr1_-_36851484 3.309 NM_032017
STK40
serine/threonine kinase 40
chr1_-_32281577 3.278 NM_144569
SPOCD1
SPOC domain containing 1
chr20_-_36793646 3.252 NM_004613
NM_198951
TGM2

transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)

chr8_-_145638929 3.219 SLC39A4
solute carrier family 39 (zinc transporter), member 4
chr12_-_113909876 3.212 NM_022363
LHX5
LIM homeobox 5
chr7_+_97841565 3.207 NM_177455
BHLHA15
basic helix-loop-helix family, member a15
chr22_-_36783851 3.207 MYH9
myosin, heavy chain 9, non-muscle
chr16_+_2039945 3.197 NM_004209
SYNGR3
synaptogyrin 3
chr20_-_1165116 3.183 NM_018354
TMEM74B
transmembrane protein 74B
chr11_-_125366048 3.180 NM_005103
NM_022549
FEZ1

fasciculation and elongation protein zeta 1 (zygin I)

chr5_-_172756505 3.179 NM_003714
STC2
stanniocalcin 2
chr19_-_1513187 3.170 NM_213604
ADAMTSL5
ADAMTS-like 5
chr4_-_2935851 3.166 NM_001120
MFSD10
major facilitator superfamily domain containing 10
chr1_+_101702561 3.162 S1PR1
sphingosine-1-phosphate receptor 1
chr1_-_201475966 3.146 NM_001193571
CSRP1
cysteine and glycine-rich protein 1
chr11_+_46403205 3.136 NM_002391
MDK
midkine (neurite growth-promoting factor 2)
chr10_-_135090325 3.122 NM_001109
NM_001164489
NM_001164490
ADAM8


ADAM metallopeptidase domain 8


chr1_-_85358851 3.114 NM_012152
LPAR3
lysophosphatidic acid receptor 3
chr22_+_42470247 3.091 NM_001002034
FAM109B
family with sequence similarity 109, member B
chr4_-_2936458 3.089 MFSD10
major facilitator superfamily domain containing 10
chr16_+_2732526 3.086 KCTD5
potassium channel tetramerisation domain containing 5
chr3_-_197282805 3.082 NM_004051
NM_203314
BDH1

3-hydroxybutyrate dehydrogenase, type 1

chr16_+_2732475 3.061 NM_018992
KCTD5
potassium channel tetramerisation domain containing 5
chr10_+_75532065 3.059 FUT11
fucosyltransferase 11 (alpha (1,3) fucosyltransferase)
chr1_-_201476241 3.047 CSRP1
cysteine and glycine-rich protein 1
chr11_-_128392061 3.032 NM_001162422
NM_005238
ETS1

v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)

chr3_-_57199313 3.025 IL17RD
interleukin 17 receptor D
chr19_-_1512997 3.017 ADAMTSL5
ADAMTS-like 5
chr22_-_36783977 3.005 MYH9
myosin, heavy chain 9, non-muscle
chr1_-_201476218 2.994 CSRP1
cysteine and glycine-rich protein 1
chr22_-_36783930 2.986 MYH9
myosin, heavy chain 9, non-muscle
chr19_+_35521591 2.919 NM_001037
NM_199037
SCN1B

sodium channel, voltage-gated, type I, beta

chr1_-_6546013 2.913 NM_001042665
PLEKHG5
pleckstrin homology domain containing, family G (with RhoGef domain) member 5
chr3_-_185542807 2.893 NM_001007225
NM_006548
IGF2BP2

insulin-like growth factor 2 mRNA binding protein 2

chr19_+_16187266 2.885 TPM4
tropomyosin 4
chr20_+_35169876 2.881 NM_006097
NM_181526
MYL9

myosin, light chain 9, regulatory

chr22_-_45608346 2.872 NM_015264
KIAA0930
KIAA0930
chr19_+_48828627 2.862 NM_001425
EMP3
epithelial membrane protein 3
chr9_+_33750463 2.857 NM_001197097
NM_007343
NM_001197098
PRSS3


protease, serine, 3


chr19_+_16187306 2.836 TPM4
tropomyosin 4
chr17_-_62658311 2.820 NM_022739
SMURF2
SMAD specific E3 ubiquitin protein ligase 2
chr8_-_145018057 2.806 NM_201382
PLEC
plectin
chr10_+_64133915 2.806 NM_014951
NM_199450
NM_199451
ZNF365


zinc finger protein 365


chr16_+_82660573 2.786 CDH13
cadherin 13, H-cadherin (heart)
chr20_+_35169897 2.783 MYL9
myosin, light chain 9, regulatory
chr1_+_90098693 2.772 LRRC8C
leucine rich repeat containing 8 family, member C
chr10_+_75532043 2.750 NM_173540
FUT11
fucosyltransferase 11 (alpha (1,3) fucosyltransferase)
chr17_+_38119225 2.748 NM_178171
GSDMA
gasdermin A
chr2_-_216300770 2.744 NM_002026
NM_054034
NM_212474
NM_212476
NM_212478
NM_212482
FN1





fibronectin 1





chr8_-_145018904 2.742 NM_201381
PLEC
plectin
chr2_-_216300444 2.740 FN1
fibronectin 1
chr1_+_160175146 2.740 PEA15
phosphoprotein enriched in astrocytes 15
chr20_+_36531498 2.724 NM_080607
VSTM2L
V-set and transmembrane domain containing 2 like
chr1_-_153044083 2.713 NM_001017418
SPRR2B
small proline-rich protein 2B
chr4_-_2936563 2.706 NM_001146069
MFSD10
major facilitator superfamily domain containing 10
chr17_-_62657997 2.687 SMURF2
SMAD specific E3 ubiquitin protein ligase 2
chr18_+_12948010 2.686 SEH1L
SEH1-like (S. cerevisiae)
chr12_+_58003962 2.685 NM_001111270
ARHGEF25
Rho guanine nucleotide exchange factor (GEF) 25
chr22_-_39639967 2.684 PDGFB
platelet-derived growth factor beta polypeptide
chr20_-_62711160 2.681 NM_001039467
RGS19
regulator of G-protein signaling 19
chr3_+_32433342 2.671 CMTM7
CKLF-like MARVEL transmembrane domain containing 7
chr7_-_143059144 2.661 NM_014690
FAM131B
family with sequence similarity 131, member B
chr1_+_90098643 2.659 NM_032270
LRRC8C
leucine rich repeat containing 8 family, member C
chr12_+_111843743 2.644 NM_005475
SH2B3
SH2B adaptor protein 3
chr11_+_69455837 2.635 NM_053056
CCND1
cyclin D1
chr8_+_25042254 2.632 NM_024940
DOCK5
dedicator of cytokinesis 5
chr1_+_26606443 2.630 SH3BGRL3
SH3 domain binding glutamic acid-rich protein like 3
chr20_+_44746948 2.620 CD40
CD40 molecule, TNF receptor superfamily member 5
chr19_-_19006868 2.602 NM_021267
NM_198207
NM_001492
CERS1

GDF1
ceramide synthase 1

growth differentiation factor 1
chr19_-_19052032 2.588 NM_004838
HOMER3
homer homolog 3 (Drosophila)
chr18_+_77155966 2.581 NFATC1
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
chr3_-_45267620 2.580 TMEM158
transmembrane protein 158 (gene/pseudogene)
chr6_+_35310317 2.576 NM_001171818
NM_001171819
NM_001171820
NM_006238
NM_177435
PPARD




peroxisome proliferator-activated receptor delta




chr1_-_36851517 2.572 STK40
serine/threonine kinase 40
chr9_-_86153048 2.571 NM_001244959
NM_174938
FRMD3

FERM domain containing 3

chr19_+_17858504 2.570 NM_001161357
NM_001161358
FCHO1

FCH domain only 1

chr2_+_173292306 2.565 NM_000210
NM_001079818
ITGA6

integrin, alpha 6

chr1_+_15736387 2.557 NM_024329
EFHD2
EF-hand domain family, member D2
chr22_-_28315150 2.556 PITPNB
phosphatidylinositol transfer protein, beta
chr6_+_35310336 2.548 PPARD
peroxisome proliferator-activated receptor delta
chr3_-_185542744 2.544 IGF2BP2
insulin-like growth factor 2 mRNA binding protein 2
chr6_+_35310368 2.537 PPARD
peroxisome proliferator-activated receptor delta
chr10_-_17271955 2.534


chr13_-_20767036 2.532 GJB2
gap junction protein, beta 2, 26kDa
chr19_-_2721337 2.531 NM_145173
DIRAS1
DIRAS family, GTP-binding RAS-like 1
chr7_-_127670995 2.530 NM_022143
LRRC4
leucine rich repeat containing 4
chr3_-_27763784 2.527 NM_005442
EOMES
eomesodermin
chr1_-_201476248 2.525 NM_001193570
NM_004078
CSRP1

cysteine and glycine-rich protein 1

chr22_-_20255614 2.523 NM_023004
RTN4R
reticulon 4 receptor
chr7_+_143058794 2.510 ZYX
zyxin
chr3_+_32433151 2.505 NM_138410
NM_181472
CMTM7

CKLF-like MARVEL transmembrane domain containing 7

chr17_-_46115135 2.504 NM_016429
COPZ2
coatomer protein complex, subunit zeta 2
chr16_+_30389632 2.497 NM_001214906
NM_001214907
ZNF48

zinc finger protein 48

chr15_-_40600025 2.490 PLCB2
phospholipase C, beta 2
chr2_+_173292081 2.486 ITGA6
integrin, alpha 6
chr22_-_36784055 2.464 NM_002473
MYH9
myosin, heavy chain 9, non-muscle
chr11_+_46403260 2.462 MDK
midkine (neurite growth-promoting factor 2)
chr11_+_69924407 2.460 NM_018043
ANO1
anoctamin 1, calcium activated chloride channel
chr19_+_15218141 2.446 NM_033025
SYDE1
synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
chrX_+_102631408 2.445 NGFRAP1
nerve growth factor receptor (TNFRSF16) associated protein 1
chr17_-_1083008 2.442 NM_021962
ABR
active BCR-related gene
chr10_-_62703822 2.438 NM_001242359
NM_014836
RHOBTB1

Rho-related BTB domain containing 1

chr1_+_228337414 2.438 NM_020435
GJC2
gap junction protein, gamma 2, 47kDa
chr14_-_71275732 2.434 NM_033141
MAP3K9
mitogen-activated protein kinase kinase kinase 9
chr1_+_215256559 2.417 NM_001017425
NM_014217
KCNK2

potassium channel, subfamily K, member 2

chr18_+_12308242 2.410 NM_032525
TUBB6
tubulin, beta 6 class V
chr22_-_36784001 2.408 MYH9
myosin, heavy chain 9, non-muscle
chr19_+_12273866 2.405 NM_003437
ZNF136
zinc finger protein 136
chr1_-_6557471 2.388 NM_001042663
PLEKHG5
pleckstrin homology domain containing, family G (with RhoGef domain) member 5
chr3_-_53880403 2.387 NM_018397
CHDH
choline dehydrogenase
chr1_-_153067000 2.385 NM_001024209
SPRR2E
small proline-rich protein 2E
chr9_+_125133228 2.384 NM_000962
NM_080591
PTGS1

prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)

chr19_+_49055421 2.382 NM_177973
SULT2B1
sulfotransferase family, cytosolic, 2B, member 1
chr16_+_82660641 2.380 CDH13
cadherin 13, H-cadherin (heart)

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
2.05 3.75e-07 GO:0051239 regulation of multicellular organismal process
1.78 4.23e-07 GO:0048869 cellular developmental process
1.78 6.63e-07 GO:0030154 cell differentiation
1.97 6.90e-07 GO:0009966 regulation of signal transduction
1.87 1.91e-06 GO:0023051 regulation of signaling
1.31 4.18e-06 GO:0050794 regulation of cellular process
1.77 5.98e-06 GO:0048583 regulation of response to stimulus
1.27 1.04e-05 GO:0065007 biological regulation
1.29 1.22e-05 GO:0050789 regulation of biological process
1.85 1.98e-05 GO:0009653 anatomical structure morphogenesis
1.47 3.66e-05 GO:0032502 developmental process
1.47 3.93e-05 GO:0023052 signaling
2.03 1.56e-04 GO:0042127 regulation of cell proliferation
1.49 2.10e-04 GO:0048856 anatomical structure development
1.46 3.15e-04 GO:0007165 signal transduction
1.62 3.47e-04 GO:0048523 negative regulation of cellular process
2.14 4.52e-04 GO:2000026 regulation of multicellular organismal development
1.45 5.96e-04 GO:0007275 multicellular organismal development
1.53 3.68e-03 GO:0048519 negative regulation of biological process
1.48 4.32e-03 GO:0048518 positive regulation of biological process
1.47 4.38e-03 GO:0048731 system development
1.36 5.05e-03 GO:0051716 cellular response to stimulus
1.49 1.10e-02 GO:0048522 positive regulation of cellular process
1.14 1.32e-02 GO:0009987 cellular process
1.87 1.33e-02 GO:0050793 regulation of developmental process
2.18 1.58e-02 GO:0008284 positive regulation of cell proliferation
1.78 1.84e-02 GO:0010646 regulation of cell communication
1.62 3.67e-02 GO:0007399 nervous system development

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
9.28 3.17e-06 GO:0042641 actomyosin
1.74 4.03e-05 GO:0005856 cytoskeleton
8.94 9.98e-05 GO:0001725 stress fiber
8.35 1.94e-04 GO:0032432 actin filament bundle
4.28 2.58e-04 GO:0005924 cell-substrate adherens junction
4.12 4.33e-04 GO:0030055 cell-substrate junction
4.22 6.86e-04 GO:0005925 focal adhesion
1.53 7.73e-04 GO:0044459 plasma membrane part
2.63 1.45e-03 GO:0015629 actin cytoskeleton
1.34 1.82e-03 GO:0005886 plasma membrane
2.06 2.34e-03 GO:0030054 cell junction
1.33 3.03e-03 GO:0071944 cell periphery
1.75 4.08e-03 GO:0044421 extracellular region part
3.18 7.47e-03 GO:0005912 adherens junction
3.04 8.04e-03 GO:0070161 anchoring junction
1.83 1.01e-02 GO:0005615 extracellular space
2.80 2.36e-02 GO:0031252 cell leading edge
2.16 3.45e-02 GO:0031012 extracellular matrix
20.87 4.98e-02 GO:0005862 muscle thin filament tropomyosin

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
1.26 3.51e-05 GO:0005515 protein binding
2.16 1.82e-03 GO:0008092 cytoskeletal protein binding
2.98 2.49e-02 GO:0008083 growth factor activity
1.66 4.90e-02 GO:0005102 receptor binding