Motif ID: UUGGCAC

Z-value: 0.542


Mature miRNA associated with seed UUGGCAC:

NamemiRBase Accession
hsa-miR-1271 MIMAT0005796
hsa-miR-96 MIMAT0000095



Activity profile for motif UUGGCAC.

activity profile for motif UUGGCAC


Sorted Z-values histogram for motif UUGGCAC

Sorted Z-values for motif UUGGCAC



Network of associatons between targets according to the STRING database.



First level regulatory network of UUGGCAC

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_-_158380360 3.557 NM_002847
NM_130842
NM_130843
PTPRN2


protein tyrosine phosphatase, receptor type, N polypeptide 2


chrX_-_107019001 3.503 NM_198057
TSC22D3
TSC22 domain family, member 3
chrX_-_106959597 3.384 NM_001015881
TSC22D3
TSC22 domain family, member 3
chrX_-_106960268 3.268 NM_004089
TSC22D3
TSC22 domain family, member 3
chr8_-_11324184 3.253 NM_053279
FAM167A
family with sequence similarity 167, member A
chr14_+_64680858 3.237 NM_182913
SYNE2
spectrin repeat containing, nuclear envelope 2
chr2_+_85980600 3.212 NM_032827
ATOH8
atonal homolog 8 (Drosophila)
chr8_+_17396285 3.132 NM_001164771
NM_003046
SLC7A2

solute carrier family 7 (cationic amino acid transporter, y+ system), member 2

chr8_+_17354562 3.029 NM_001008539
SLC7A2
solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
chr16_+_23194037 2.941 NM_001039
SCNN1G
sodium channel, nonvoltage-gated 1, gamma
chr13_-_41240607 2.893 NM_002015
FOXO1
forkhead box O1
chr14_+_64682671 2.849 NM_182910
SYNE2
spectrin repeat containing, nuclear envelope 2
chr2_-_230135954 2.848 NM_001100818
NM_017933
PID1

phosphotyrosine interaction domain containing 1

chr3_-_87040246 2.846 NM_016206
VGLL3
vestigial like 3 (Drosophila)
chr1_+_9352931 2.731 NM_025106
SPSB1
splA/ryanodine receptor domain and SOCS box containing 1
chr2_+_103236147 2.669 NM_003048
SLC9A2
solute carrier family 9 (sodium/hydrogen exchanger), member 2
chr19_-_49016418 2.608 NM_001080434
LMTK3
lemur tyrosine kinase 3
chr7_+_140774031 2.604 NM_001195278
LOC100507421
transmembrane protein 178-like
chr11_-_2906960 2.592 NM_000076
NM_001122630
NM_001122631
CDKN1C


cyclin-dependent kinase inhibitor 1C (p57, Kip2)


chr3_-_157823815 2.474 NM_001163678
NM_003030
NM_006884
SHOX2


short stature homeobox 2


chr7_-_47621741 2.469 NM_022748
TNS3
tensin 3
chr14_+_64319607 2.467 NM_015180
NM_182914
SYNE2

spectrin repeat containing, nuclear envelope 2

chr16_+_77822400 2.279 NM_020927
VAT1L
vesicle amine transport protein 1 homolog (T. californica)-like
chr19_+_54369610 2.168 NM_001020820
MYADM
myeloid-associated differentiation marker
chr19_+_54372659 2.155 NM_001020821
NM_001020818
MYADM

myeloid-associated differentiation marker

chr4_+_86396251 2.136 NM_001025616
ARHGAP24
Rho GTPase activating protein 24
chr9_+_79115548 2.130 NM_001097636
GCNT1
glucosaminyl (N-acetyl) transferase 1, core 2
chr14_-_23623493 2.125 NM_182728
SLC7A8
solute carrier family 7 (amino acid transporter light chain, L system), member 8
chr9_+_79074067 2.090 NM_001097633
NM_001490
GCNT1

glucosaminyl (N-acetyl) transferase 1, core 2

chr9_+_79093256 2.089 NM_001097635
GCNT1
glucosaminyl (N-acetyl) transferase 1, core 2
chr19_+_54371125 2.008 NM_001020819
NM_138373
MYADM

myeloid-associated differentiation marker

chr16_+_85061303 2.008 NM_014732
KIAA0513
KIAA0513
chr14_-_23652840 1.989 NM_012244
SLC7A8
solute carrier family 7 (amino acid transporter light chain, L system), member 8
chr9_+_79056581 1.971 NM_001097634
GCNT1
glucosaminyl (N-acetyl) transferase 1, core 2
chr17_+_7311501 1.919 NM_020795
NLGN2
neuroligin 2
chr18_+_20735788 1.915 NM_138375
CABLES1
Cdk5 and Abl enzyme substrate 1
chr6_+_108881010 1.900 NM_201559
FOXO3
forkhead box O3
chr22_+_21321446 1.893 NM_001146288
AIFM3
apoptosis-inducing factor, mitochondrion-associated, 3
chr22_+_21319417 1.890 NM_001018060
NM_144704
AIFM3

apoptosis-inducing factor, mitochondrion-associated, 3

chr19_+_7911385 1.869 NM_001159944
EVI5L
ecotropic viral integration site 5-like
chr12_+_60083125 1.828 NM_004731
SLC16A7
solute carrier family 16, member 7 (monocarboxylic acid transporter 2)
chr18_+_20715726 1.812 NM_001100619
CABLES1
Cdk5 and Abl enzyme substrate 1
chr7_-_51384458 1.797 NM_015198
COBL
cordon-bleu homolog (mouse)
chr9_-_140115774 1.767 NM_031297
RNF208
ring finger protein 208
chr6_-_16761600 1.765 NM_000332
NM_001128164
ATXN1

ataxin 1

chr9_+_102584136 1.704 NM_006981
NM_173199
NM_173200
NR4A3


nuclear receptor subfamily 4, group A, member 3


chr14_-_90085325 1.669 NM_001085471
FOXN3
forkhead box N3
chr1_-_53018721 1.648 NM_001009881
NM_015269
ZCCHC11

zinc finger, CCHC domain containing 11

chr3_+_23986735 1.629 NM_005126
NR1D2
nuclear receptor subfamily 1, group D, member 2
chr3_+_69915374 1.614 NM_198177
MITF
microphthalmia-associated transcription factor
chr5_+_31799030 1.612 NM_178140
PDZD2
PDZ domain containing 2
chr11_+_65554504 1.610 NM_004561
OVOL1
ovo-like 1(Drosophila)
chr19_+_10736167 1.610 NM_020428
SLC44A2
solute carrier family 44, member 2
chr12_-_96184510 1.603 NM_021229
NTN4
netrin 4
chr3_+_69812961 1.569 NM_006722
MITF
microphthalmia-associated transcription factor
chr12_-_56727720 1.562 NM_001166279
NM_014871
PAN2

PAN2 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)

chr10_-_73533196 1.559 NM_022153
C10orf54
chromosome 10 open reading frame 54
chr5_+_131705353 1.547 NM_003060
SLC22A5
solute carrier family 22 (organic cation/carnitine transporter), member 5
chr8_+_38644721 1.536 NM_001122824
NM_006283
TACC1

transforming, acidic coiled-coil containing protein 1

chr5_+_133861685 1.536 NM_015288
PHF15
PHD finger protein 15
chr8_+_38585703 1.531 NM_001146216
TACC1
transforming, acidic coiled-coil containing protein 1
chr6_+_108882068 1.521 NM_001455
FOXO3
forkhead box O3
chr12_-_56727446 1.507 NM_001127460
PAN2
PAN2 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
chr19_+_42817434 1.497 NM_173633
TMEM145
transmembrane protein 145
chr6_-_30710219 1.482 NM_005803
FLOT1
flotillin 1
chr11_+_76777926 1.475 NM_004055
CAPN5
calpain 5
chr2_+_219824346 1.475 NM_003936
CDK5R2
cyclin-dependent kinase 5, regulatory subunit 2 (p39)
chr19_-_49314177 1.470 NM_001164773
NM_001190
BCAT2

branched chain amino-acid transaminase 2, mitochondrial

chr16_+_50775960 1.463 NM_001042355
NM_015247
CYLD

cylindromatosis (turban tumor syndrome)

chr16_+_50776012 1.463 NM_001042412
CYLD
cylindromatosis (turban tumor syndrome)
chr3_+_69812620 1.439 NM_001184967
MITF
microphthalmia-associated transcription factor
chr10_+_114709963 1.415 NM_001146274
NM_001146283
NM_001146284
NM_001146285
NM_001146286
NM_001198525
NM_001198526
NM_001198527
NM_001198528
NM_001198529
NM_001198530
NM_001198531
NM_030756
TCF7L2












transcription factor 7-like 2 (T-cell specific, HMG-box)












chr19_+_7895110 1.408 NM_145245
EVI5L
ecotropic viral integration site 5-like
chr1_-_76076762 1.377 NM_001130058
NM_152697
SLC44A5

solute carrier family 44, member 5

chr4_+_86851425 1.355 NM_031305
ARHGAP24
Rho GTPase activating protein 24
chr15_-_34610928 1.353 NM_005135
SLC12A6
solute carrier family 12 (potassium/chloride transporters), member 6
chr2_-_218808705 1.330 NM_022648
TNS1
tensin 1
chr19_+_10713055 1.329 NM_001145056
SLC44A2
solute carrier family 44, member 2
chr20_+_33292117 1.327 NM_021202
TP53INP2
tumor protein p53 inducible nuclear protein 2
chr12_-_106533810 1.320 NM_014840
NUAK1
NUAK family, SNF1-like kinase, 1
chr3_-_134093235 1.312 NM_016201
AMOTL2
angiomotin like 2
chr3_+_23987514 1.282 NM_001145425
NR1D2
nuclear receptor subfamily 1, group D, member 2
chr3_+_69788562 1.279 NM_198159
MITF
microphthalmia-associated transcription factor
chr17_-_26733185 1.279 NM_001242366
NM_080669
SLC46A1

solute carrier family 46 (folate transporter), member 1

chr4_-_89744154 1.246 NM_001015045
FAM13A
family with sequence similarity 13, member A
chr11_-_66675334 1.237 NM_022172
PC
pyruvate carboxylase
chr1_+_192778168 1.235 NM_002923
RGS2
regulator of G-protein signaling 2, 24kDa
chr14_-_89883306 1.230 NM_005197
FOXN3
forkhead box N3
chr8_-_22550057 1.211 NM_001199881
EGR3
early growth response 3
chr19_-_48894755 1.211 NM_006801
KDELR1
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1
chr19_+_19174792 1.191 NM_178526
SLC25A42
solute carrier family 25, member 42
chr3_+_69985750 1.177 NM_000248
NM_001184968
NM_198158
NM_198178
MITF



microphthalmia-associated transcription factor



chr15_-_34629044 1.174 NM_001042497
NM_133647
SLC12A6

solute carrier family 12 (potassium/chloride transporters), member 6

chr8_-_22550708 1.172 NM_004430
EGR3
early growth response 3
chr8_-_22549901 1.171 NM_001199880
EGR3
early growth response 3
chr3_+_194406614 1.166 NM_153690
FAM43A
family with sequence similarity 43, member A
chr10_-_81965327 1.158 NM_001157
NM_145868
NM_145869
ANXA11


annexin A11


chr15_-_43212911 1.155 NM_173500
TTBK2
tau tubulin kinase 2
chr21_-_44846927 1.153 NM_173354
SIK1
salt-inducible kinase 1
chr8_+_102504661 1.140 NM_024915
GRHL2
grainyhead-like 2 (Drosophila)
chr1_-_44482996 1.119 NM_006934
NM_201649
SLC6A9

solute carrier family 6 (neurotransmitter transporter, glycine), member 9

chr12_+_32654976 1.115 NM_139241
FGD4
FYVE, RhoGEF and PH domain containing 4
chr19_+_48958765 1.112 NM_013348
KCNJ14
potassium inwardly-rectifying channel, subfamily J, member 14
chr2_+_235860616 1.109 NM_014521
SH3BP4
SH3-domain binding protein 4
chr15_-_56035176 1.107 NM_173814
PRTG
protogenin
chr10_+_24497719 1.101 NM_001098501
NM_019590
KIAA1217

KIAA1217

chr19_+_57106622 1.087 NM_021216
ZNF71
zinc finger protein 71
chr6_+_88182624 1.065 NM_001168398
NM_006416
SLC35A1

solute carrier family 35 (CMP-sialic acid transporter), member A1

chr1_-_153940187 1.056 NM_014437
SLC39A1
solute carrier family 39 (zinc transporter), member 1
chr19_-_55628780 1.049 NM_017607
PPP1R12C
protein phosphatase 1, regulatory subunit 12C
chr1_-_205912546 1.043 NM_052934
NM_134325
SLC26A9

solute carrier family 26, member 9

chr5_-_126366439 1.041 NM_178450
MARCH3
membrane-associated ring finger (C3HC4) 3
chrX_-_106449543 1.030 NM_017681
NUP62CL
nucleoporin 62kDa C-terminal like
chr4_+_108814419 1.027 NM_001136257
NM_152621
SGMS2

sphingomyelin synthase 2

chr19_-_45909566 1.024 NM_001142502
PPP1R13L
protein phosphatase 1, regulatory subunit 13 like
chr12_-_58026846 1.023 NM_001478
B4GALNT1
beta-1,4-N-acetyl-galactosaminyl transferase 1
chr11_+_109964086 1.018 NM_033390
ZC3H12C
zinc finger CCCH-type containing 12C
chr10_+_104678001 1.017 NM_017649
NM_199076
NM_199077
CNNM2


cyclin M2


chr22_-_39268230 1.015 NM_014292
CBX6
chromobox homolog 6
chr1_-_44497132 1.002 NM_001024845
SLC6A9
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr11_-_66725790 1.000 NM_000920
NM_001040716
PC

pyruvate carboxylase

chr10_+_35535952 1.000 NM_181698
CCNY
cyclin Y
chr10_+_35625608 0.993 NM_145012
CCNY
cyclin Y
chr11_-_110167191 0.988 NM_002906
RDX
radixin
chr2_-_44587812 0.985 NM_006036
PREPL
prolyl endopeptidase-like
chr17_-_1532109 0.984 NM_152346
SLC43A2
solute carrier family 43, member 2
chr6_+_1312674 0.982 NM_033260
FOXQ1
forkhead box Q1
chr2_-_151344145 0.981 NM_005168
RND3
Rho family GTPase 3
chr4_+_2061238 0.973 NM_178557
NAT8L
N-acetyltransferase 8-like (GCN5-related, putative)
chr19_+_34663311 0.973 NM_001114093
NM_015578
LSM14A

LSM14A, SCD6 homolog A (S. cerevisiae)

chr19_-_45908288 0.963 NM_006663
PPP1R13L
protein phosphatase 1, regulatory subunit 13 like
chr5_+_118407067 0.960 NM_005509
DMXL1
Dmx-like 1
chr17_+_18163836 0.959 NM_001144900
NM_139162
SMCR7

Smith-Magenis syndrome chromosome region, candidate 7

chr7_-_131241321 0.956 NM_001018111
NM_005397
PODXL

podocalyxin-like

chr7_-_95225802 0.947 NM_002612
PDK4
pyruvate dehydrogenase kinase, isozyme 4
chr11_-_64612040 0.944 NM_017525
CDC42BPG
CDC42 binding protein kinase gamma (DMPK-like)
chr5_-_172756505 0.940 NM_003714
STC2
stanniocalcin 2
chr12_-_26985922 0.935 NM_002223
ITPR2
inositol 1,4,5-trisphosphate receptor, type 2
chr6_-_119031230 0.935 NM_001178035
CEP85L
centrosomal protein 85kDa-like
chr12_-_31743822 0.935 NM_144973
DENND5B
DENN/MADD domain containing 5B
chr3_-_50540853 0.934 NM_001005505
NM_001174051
NM_006030
CACNA2D2


calcium channel, voltage-dependent, alpha 2/delta subunit 2


chr7_-_105925410 0.931 NM_005746
NAMPT
nicotinamide phosphoribosyltransferase
chr6_-_45983279 0.927 NM_016929
CLIC5
chloride intracellular channel 5
chr11_-_8680382 0.925 NM_014818
TRIM66
tripartite motif containing 66
chr15_-_72490109 0.919 NM_001012642
GRAMD2
GRAM domain containing 2
chr1_-_156470506 0.917 NM_005920
MEF2D
myocyte enhancer factor 2D
chr12_-_49177876 0.907 NM_015270
ADCY6
adenylate cyclase 6
chr3_-_141747434 0.899 NM_001178141
NM_001178142
NM_006286
TFDP2


transcription factor Dp-2 (E2F dimerization partner 2)


chr4_+_108745718 0.895 NM_001136258
SGMS2
sphingomyelin synthase 2
chr2_+_45878912 0.894 NM_005400
PRKCE
protein kinase C, epsilon
chr4_+_86699846 0.889 NM_001042669
ARHGAP24
Rho GTPase activating protein 24
chr5_-_59783885 0.873 NM_001165899
PDE4D
phosphodiesterase 4D, cAMP-specific
chr20_+_42544781 0.859 NM_001098796
NM_032883
TOX2

TOX high mobility group box family member 2

chr5_+_67588395 0.857 NM_001242466
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr3_-_195808997 0.856 NM_001128148
TFRC
transferrin receptor (p90, CD71)
chr9_-_112083005 0.856 NM_018424
NM_019114
EPB41L4B

erythrocyte membrane protein band 4.1 like 4B

chr12_-_49182718 0.855 NM_020983
ADCY6
adenylate cyclase 6
chr3_-_9994057 0.849 NM_207351
PRRT3
proline-rich transmembrane protein 3
chr11_+_76494132 0.849 NM_015516
TSKU
tsukushi small leucine rich proteoglycan homolog (Xenopus laevis)
chr17_+_18164423 0.849 NM_148886
SMCR7
Smith-Magenis syndrome chromosome region, candidate 7
chr16_-_20911560 0.842 NM_173475
DCUN1D3
DCN1, defective in cullin neddylation 1, domain containing 3 (S. cerevisiae)
chr2_-_167232464 0.841 NM_002977
SCN9A
sodium channel, voltage-gated, type IX, alpha subunit
chr1_+_28764660 0.840 NM_023923
PHACTR4
phosphatase and actin regulator 4
chr8_-_124544376 0.833 NM_148177
FBXO32
F-box protein 32
chr2_+_54952148 0.828 NM_001039753
EML6
echinoderm microtubule associated protein like 6
chr9_-_139922705 0.821 NM_001606
ABCA2
ATP-binding cassette, sub-family A (ABC1), member 2
chr2_+_169312793 0.819 NM_203463
CERS6
ceramide synthase 6
chr5_-_114938060 0.819 NM_021649
TICAM2
toll-like receptor adaptor molecule 2
chr7_+_44646120 0.816 NM_001003941
NM_001165036
NM_002541
OGDH


oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)


chr17_+_61699786 0.815 NM_002401
NM_203351
MAP3K3

mitogen-activated protein kinase kinase kinase 3

chr2_-_220094354 0.813 NM_001077198
NM_024085
ATG9A

ATG9 autophagy related 9 homolog A (S. cerevisiae)

chr2_-_44588622 0.806 NM_001171606
NM_001171613
PREPL

prolyl endopeptidase-like

chr3_+_150804675 0.801 NM_053002
MED12L
mediator complex subunit 12-like
chr10_+_23983674 0.798 NM_001098500
KIAA1217
KIAA1217
chr17_-_48227873 0.795 NM_032595
PPP1R9B
protein phosphatase 1, regulatory subunit 9B
chr4_-_140477290 0.793 NM_030648
SETD7
SET domain containing (lysine methyltransferase) 7
chr3_-_195808958 0.793 NM_003234
TFRC
transferrin receptor (p90, CD71)
chr15_+_94841429 0.791 NM_001159643
NM_018349
MCTP2

multiple C2 domains, transmembrane 2

chr10_+_111765725 0.791 NM_019903
ADD3
adducin 3 (gamma)
chr13_+_39612440 0.786 NM_001012754
NM_001017370
NHLRC3

NHL repeat containing 3

chr11_-_16424391 0.782 NM_001145819
NM_017508
SOX6

SRY (sex determining region Y)-box 6

chr15_-_34630203 0.779 NM_001042495
SLC12A6
solute carrier family 12 (potassium/chloride transporters), member 6
chr7_-_1595746 0.775 NM_001097620
TMEM184A
transmembrane protein 184A
chr6_-_32157511 0.774 NM_002586
PBX2
pre-B-cell leukemia homeobox 2
chrX_-_30907408 0.773 NM_152787
TAB3
TGF-beta activated kinase 1/MAP3K7 binding protein 3
chr19_+_50168398 0.769 NM_001040668
NM_138639
BCL2L12

BCL2-like 12 (proline rich)

chr16_-_1429612 0.763 NM_001193389
NM_023076
UNKL

unkempt homolog (Drosophila)-like

chr17_+_17942584 0.753 NM_024052
C17orf39
chromosome 17 open reading frame 39
chr1_+_155146324 0.752 NM_025058
TRIM46
tripartite motif containing 46
chr9_+_130854127 0.752 NM_001006642
SLC25A25
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25
chr3_+_187943192 0.747 NM_001167671
LPP
LIM domain containing preferred translocation partner in lipoma
chr1_-_32860014 0.745 NM_001143888
NM_001143889
NM_001143890
NM_018045
BSDC1



BSD domain containing 1



chr19_-_14316980 0.745 NM_001008701
NM_014921
LPHN1

latrophilin 1

chr5_-_16509106 0.742 NM_019000
FAM134B
family with sequence similarity 134, member B
chr17_+_77751929 0.739 NM_005189
NM_032647
CBX2

chromobox homolog 2

chr19_+_48964505 0.732 NM_170720
KCNJ14
potassium inwardly-rectifying channel, subfamily J, member 14
chr1_+_65210724 0.729 NM_018211
RAVER2
ribonucleoprotein, PTB-binding 2
chr1_+_178694273 0.723 NM_152663
RALGPS2
Ral GEF with PH domain and SH3 binding motif 2
chr5_-_126409171 0.720 NM_001164478
NM_001164479
C5orf63

chromosome 5 open reading frame 63

chr3_-_171528227 0.719 NM_001130081
NM_002662
PLD1

phospholipase D1, phosphatidylcholine-specific


Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
10.18 4.49e-04 GO:0071705 nitrogen compound transport
11.14 1.20e-03 GO:0015837 amine transport
3.87 4.98e-03 GO:0055085 transmembrane transport
24.67 7.76e-03 GO:0015695 organic cation transport
30.53 4.81e-02 GO:0015697 quaternary ammonium group transport
10.29 4.91e-02 GO:0006865 amino acid transport

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
6.23 1.25e-02 GO:0016323 basolateral plasma membrane

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
6.59 8.63e-05 GO:0022804 active transmembrane transporter activity
15.08 3.03e-04 GO:0005275 amine transmembrane transporter activity
7.24 5.51e-03 GO:0015291 secondary active transmembrane transporter activity
3.22 1.04e-02 GO:0022857 transmembrane transporter activity
9.99 1.56e-02 GO:0046943 carboxylic acid transmembrane transporter activity
9.79 1.71e-02 GO:0005342 organic acid transmembrane transporter activity
3.22 1.87e-02 GO:0022891 substrate-specific transmembrane transporter activity
12.16 3.54e-02 GO:0015171 amino acid transmembrane transporter activity
67.83 3.85e-02 GO:0015220 choline transmembrane transporter activity
7.84 4.82e-02 GO:0015293 symporter activity