Motif ID: TFDP1.p2

Z-value: 3.024


Transcription factors associated with TFDP1.p2:

Gene SymbolEntrez IDGene Name
TFDP1 7027 transcription factor Dp-1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
TFDP1hg19_v1_chr13_+_114239047_1142390990.844.3e-21Click!


Activity profile for motif TFDP1.p2.

activity profile for motif TFDP1.p2


Sorted Z-values histogram for motif TFDP1.p2

Sorted Z-values for motif TFDP1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TFDP1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_+_52776263 32.694 NM_006350
NM_013409
FST

follistatin

chr5_+_52776479 31.522 FST
follistatin
chr5_+_52776408 22.353 FST
follistatin
chr12_-_28122884 20.362 NM_198964
NM_198966
PTHLH

parathyroid hormone-like hormone

chr3_-_52090090 19.523 NM_001947
DUSP7
dual specificity phosphatase 7
chr2_-_235405692 19.196 NM_005737
ARL4C
ADP-ribosylation factor-like 4C
chr4_-_57976516 18.294 IGFBP7
insulin-like growth factor binding protein 7
chr16_+_22825806 18.104 NM_006043
HS3ST2
heparan sulfate (glucosamine) 3-O-sulfotransferase 2
chr12_+_66218879 16.406 HMGA2
high mobility group AT-hook 2
chrX_-_153095810 16.365 PDZD4
PDZ domain containing 4
chr17_+_30813928 15.877 NM_003885
CDK5R1
cyclin-dependent kinase 5, regulatory subunit 1 (p35)
chr16_-_325867 14.958 NM_003834
NM_183337
RGS11

regulator of G-protein signaling 11

chr4_-_57976550 14.799 NM_001253835
NM_001553
IGFBP7

insulin-like growth factor binding protein 7

chr19_-_1237840 14.629 NM_152769
C19orf26
chromosome 19 open reading frame 26
chr20_-_56284945 14.617 NM_020182
PMEPA1
prostate transmembrane protein, androgen induced 1
chrX_-_153095746 14.575 PDZD4
PDZ domain containing 4
chr15_+_101420004 14.482 NM_000693
ALDH1A3
aldehyde dehydrogenase 1 family, member A3
chr17_-_62658175 14.133 SMURF2
SMAD specific E3 ubiquitin protein ligase 2
chr12_+_66218141 13.886 NM_003483
NM_003484
HMGA2

high mobility group AT-hook 2

chrX_-_153095996 13.745 NM_032512
PDZD4
PDZ domain containing 4
chr3_-_45267620 13.364 TMEM158
transmembrane protein 158 (gene/pseudogene)
chr5_+_133450353 12.815 NM_003202
TCF7
transcription factor 7 (T-cell specific, HMG-box)
chr6_-_107435635 12.736 NM_001080450
BEND3
BEN domain containing 3
chr2_+_113403433 12.462 NM_005415
SLC20A1
solute carrier family 20 (phosphate transporter), member 1
chr1_+_90098693 12.129 LRRC8C
leucine rich repeat containing 8 family, member C
chr17_-_62658311 12.021 NM_022739
SMURF2
SMAD specific E3 ubiquitin protein ligase 2
chr18_+_43913906 11.980 RNF165
ring finger protein 165
chr6_+_37137882 11.915 NM_001243186
NM_002648
PIM1

pim-1 oncogene

chr5_-_176037091 11.465 NM_052899
GPRIN1
G protein regulated inducer of neurite outgrowth 1
chr3_+_71803200 11.373 NM_018971
GPR27
G protein-coupled receptor 27
chr6_+_151561508 11.269 AKAP12
A kinase (PRKA) anchor protein 12
chr19_+_34972866 11.188 NM_001080436
WTIP
Wilms tumor 1 interacting protein
chr15_+_101420032 11.148 ALDH1A3
aldehyde dehydrogenase 1 family, member A3
chr19_+_35521591 11.120 NM_001037
NM_199037
SCN1B

sodium channel, voltage-gated, type I, beta

chr12_+_66218568 11.091 HMGA2
high mobility group AT-hook 2
chr18_+_9708187 10.990 NM_006868
RAB31
RAB31, member RAS oncogene family
chr19_+_16187306 10.990 TPM4
tropomyosin 4
chr6_+_151561571 10.768


chr19_+_16187266 10.758 TPM4
tropomyosin 4
chr15_+_68871285 10.699 NM_006091
CORO2B
coronin, actin binding protein, 2B
chr17_+_30814552 10.641 CDK5R1
cyclin-dependent kinase 5, regulatory subunit 1 (p35)
chr19_+_16187315 10.633 TPM4
tropomyosin 4
chr9_-_86153048 10.308 NM_001244959
NM_174938
FRMD3

FERM domain containing 3

chr8_-_29207795 10.274 NM_001394
DUSP4
dual specificity phosphatase 4
chr17_+_19437140 10.257 NM_018242
SLC47A1
solute carrier family 47, member 1
chr2_-_43453724 10.121 ZFP36L2
zinc finger protein 36, C3H type-like 2
chr11_+_69924407 10.082 NM_018043
ANO1
anoctamin 1, calcium activated chloride channel
chr6_-_89827605 10.030 NM_080743
SRSF12
serine/arginine-rich splicing factor 12
chr22_+_19701968 9.949 NM_002688
SEPT5
septin 5
chr4_-_99579540 9.948 NM_005723
TSPAN5
tetraspanin 5
chr17_-_62657997 9.946 SMURF2
SMAD specific E3 ubiquitin protein ligase 2
chr3_-_127541160 9.924 NM_007283
MGLL
monoglyceride lipase
chr9_-_113800243 9.834 NM_001401
NM_057159
LPAR1

lysophosphatidic acid receptor 1

chr22_-_46373007 9.592 NM_058238
WNT7B
wingless-type MMTV integration site family, member 7B
chr4_+_3465032 9.388 NM_001164673
NM_173660
DOK7

docking protein 7

chr4_-_57976355 9.377 IGFBP7
insulin-like growth factor binding protein 7
chr3_-_13921617 9.265 NM_004625
WNT7A
wingless-type MMTV integration site family, member 7A
chr5_-_141704468 9.233 SPRY4
sprouty homolog 4 (Drosophila)
chr17_-_41623246 9.231 NM_001986
ETV4
ets variant 4
chr13_-_80915041 9.123 NM_005842
SPRY2
sprouty homolog 2 (Drosophila)
chr5_-_141704575 8.985 NM_001127496
NM_030964
SPRY4

sprouty homolog 4 (Drosophila)

chr1_-_223537400 8.924 NM_001037175
NM_017982
SUSD4

sushi domain containing 4

chr5_+_92920592 8.910 NR2F1
NR2F2
nuclear receptor subfamily 2, group F, member 1
nuclear receptor subfamily 2, group F, member 2
chr22_+_31090792 8.884 NM_030758
OSBP2
oxysterol binding protein 2
chr10_-_43762366 8.824 NM_145313
RASGEF1A
RasGEF domain family, member 1A
chr3_-_170626425 8.793 NM_020390
EIF5A2
eukaryotic translation initiation factor 5A2
chr1_+_160175114 8.749 NM_003768
PEA15
phosphoprotein enriched in astrocytes 15
chr3_-_45267804 8.734 NM_015444
TMEM158
transmembrane protein 158 (gene/pseudogene)
chr2_-_224903933 8.707 NM_001136528
NM_006216
SERPINE2

serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2

chr1_+_110753313 8.704 NM_001039574
NM_004978
KCNC4

potassium voltage-gated channel, Shaw-related subfamily, member 4

chr1_-_95392501 8.701 NM_001839
CNN3
calponin 3, acidic
chr1_+_160175146 8.701 PEA15
phosphoprotein enriched in astrocytes 15
chr11_-_113345841 8.685 NM_000795
NM_016574
DRD2

dopamine receptor D2

chr12_+_111843743 8.666 NM_005475
SH2B3
SH2B adaptor protein 3
chr2_-_233792825 8.623 NM_001114090
NGEF
neuronal guanine nucleotide exchange factor
chr3_-_170626381 8.582 EIF5A2
eukaryotic translation initiation factor 5A2
chr1_-_200992510 8.562 KIF21B
kinesin family member 21B
chr6_+_20404033 8.541 NM_001243076
E2F3
E2F transcription factor 3
chr4_-_177713664 8.517 NM_005429
VEGFC
vascular endothelial growth factor C
chr3_-_27525806 8.515 SLC4A7
solute carrier family 4, sodium bicarbonate cotransporter, member 7
chr3_-_160283166 8.454 KPNA4
karyopherin alpha 4 (importin alpha 3)
chr8_-_82024277 8.435 NM_018440
PAG1
phosphoprotein associated with glycosphingolipid microdomains 1
chr3_-_120068077 8.419 NM_001099678
LRRC58
leucine rich repeat containing 58
chr10_+_12391728 8.367 CAMK1D
calcium/calmodulin-dependent protein kinase ID
chr17_+_60705051 8.269 MRC2
mannose receptor, C type 2
chr22_-_20792107 8.264 NM_153334
NM_182895
SCARF2

scavenger receptor class F, member 2

chr22_-_36783851 8.259 MYH9
myosin, heavy chain 9, non-muscle
chr22_-_36784001 8.257 MYH9
myosin, heavy chain 9, non-muscle
chr3_-_127541975 8.232 NM_001003794
MGLL
monoglyceride lipase
chr17_+_54671059 8.215 NM_005450
NOG
noggin
chr17_+_74380676 8.210 NM_001142601
NM_021972
NM_182965
SPHK1


sphingosine kinase 1


chr1_+_215256559 8.207 NM_001017425
NM_014217
KCNK2

potassium channel, subfamily K, member 2

chr9_+_4490193 8.167 NM_004170
SLC1A1
solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
chr8_-_133492751 8.117 KCNQ3
potassium voltage-gated channel, KQT-like subfamily, member 3
chr1_+_90098624 8.086 LRRC8C
leucine rich repeat containing 8 family, member C
chr12_-_30907447 8.036 NM_001002259
NM_001206856
NM_023925
NM_032156
CAPRIN2



caprin family member 2



chr12_+_569542 8.001 NM_173593
B4GALNT3
beta-1,4-N-acetyl-galactosaminyl transferase 3
chr10_-_14646407 7.929 FAM107B
family with sequence similarity 107, member B
chr17_+_14204326 7.904 NM_006041
HS3ST3B1
heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1
chr20_-_62284701 7.805 NM_015894
STMN3
stathmin-like 3
chr13_-_20806533 7.804 NM_001110219
NM_001110220
NM_001110221
GJB6


gap junction protein, beta 6, 30kDa


chr2_-_43453146 7.804 ZFP36L2
zinc finger protein 36, C3H type-like 2
chr12_-_50101127 7.798 FMNL3
formin-like 3
chr3_-_185542744 7.787 IGF2BP2
insulin-like growth factor 2 mRNA binding protein 2
chr11_+_130318457 7.768 NM_139055
ADAMTS15
ADAM metallopeptidase with thrombospondin type 1 motif, 15
chrX_-_153095841 7.734 PDZD4
PDZ domain containing 4
chr14_-_21493122 7.713 NM_201538
NM_201539
NM_201540
NM_201541
NDRG2



NDRG family member 2



chr11_-_61348290 7.711 NM_001252065
NM_004200
SYT7

synaptotagmin VII

chr10_-_126138549 7.708 NM_001146340
NKX1-2
NK1 homeobox 2
chr3_-_27525878 7.682 SLC4A7
solute carrier family 4, sodium bicarbonate cotransporter, member 7
chr10_-_44144151 7.662 NM_001005368
ZNF32
zinc finger protein 32
chr1_+_90098643 7.626 NM_032270
LRRC8C
leucine rich repeat containing 8 family, member C
chr2_-_86564632 7.625 NM_001164731
NM_001164732
NM_022912
REEP1


receptor accessory protein 1


chr18_+_9708322 7.561 RAB31
RAB31, member RAS oncogene family
chr7_-_44365019 7.542 NM_001220
NM_172078
NM_172079
NM_172080
NM_172081
NM_172082
NM_172083
NM_172084
CAMK2B







calcium/calmodulin-dependent protein kinase II beta







chr2_+_48541767 7.537 NM_002158
FOXN2
forkhead box N2
chr4_+_41258941 7.514 UCHL1
ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
chr3_-_160283071 7.510 KPNA4
karyopherin alpha 4 (importin alpha 3)
chrX_+_37430821 7.502 NM_001170331
NM_198511
LANCL3

LanC lantibiotic synthetase component C-like 3 (bacterial)

chr22_-_20792047 7.483 SCARF2
scavenger receptor class F, member 2
chr7_+_24612714 7.443 NM_016447
MPP6
membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
chr22_+_42372763 7.443 NM_019106
NM_145733
SEPT3

septin 3

chr1_-_200992824 7.425 NM_001252100
NM_001252102
NM_001252103
NM_017596
KIF21B



kinesin family member 21B



chr6_+_151561653 7.382 AKAP12
A kinase (PRKA) anchor protein 12
chr14_-_69446038 7.329 NM_001102
NM_001130004
NM_001130005
ACTN1


actinin, alpha 1


chr2_-_215674292 7.293 NM_000465
BARD1
BRCA1 associated RING domain 1
chr15_-_101791674 7.275 CHSY1
chondroitin sulfate synthase 1
chr22_-_36783930 7.215 MYH9
myosin, heavy chain 9, non-muscle
chr3_-_16554992 7.185 RFTN1
raftlin, lipid raft linker 1
chr1_-_85358851 7.152 NM_012152
LPAR3
lysophosphatidic acid receptor 3
chr4_+_84457390 7.146 NM_032717
AGPAT9
1-acylglycerol-3-phosphate O-acyltransferase 9
chr13_+_100633977 7.144 NM_007129
ZIC2
Zic family member 2
chr7_+_69064316 7.139 AUTS2
autism susceptibility candidate 2
chr6_-_91006460 7.126 NM_021813
BACH2
BTB and CNC homology 1, basic leucine zipper transcription factor 2
chrX_+_37431015 7.123 LANCL3
LanC lantibiotic synthetase component C-like 3 (bacterial)
chr2_-_227663454 7.120 NM_005544
IRS1
insulin receptor substrate 1
chr10_+_12391708 7.115 CAMK1D
calcium/calmodulin-dependent protein kinase ID
chr22_-_36783977 7.110 MYH9
myosin, heavy chain 9, non-muscle
chr19_+_36359346 7.110 NM_001024807
NM_005166
APLP1

amyloid beta (A4) precursor-like protein 1

chr17_-_36831156 7.110 NM_001130677
C17orf96
chromosome 17 open reading frame 96
chr19_+_15218141 7.110 NM_033025
SYDE1
synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
chr8_+_32405727 7.080 NM_001160002
NM_001160004
NM_001160005
NM_001160007
NM_001160008
NM_004495
NM_013956
NM_013957
NM_013958
NM_013960
NM_013964
NRG1










neuregulin 1










chr20_-_31172874 7.055 LOC284804
uncharacterized LOC284804
chr11_+_118401755 7.050 NM_001144034
NM_001144035
NM_001144036
NM_001144037
NM_001144038
NM_032780
TMEM25





transmembrane protein 25





chr2_+_30454396 7.042 NM_030915
LBH
limb bud and heart development homolog (mouse)
chr1_-_95007139 7.034 NM_001178096
NM_001993
F3

coagulation factor III (thromboplastin, tissue factor)

chr14_-_94254765 7.013 NM_178013
PRIMA1
proline rich membrane anchor 1
chr14_-_69445974 6.992 ACTN1
actinin, alpha 1
chr5_-_1112106 6.955 NM_006598
SLC12A7
solute carrier family 12 (potassium/chloride transporters), member 7
chr10_-_92617417 6.947 HTR7
5-hydroxytryptamine (serotonin) receptor 7 (adenylate cyclase-coupled)
chr8_+_61591358 6.910 CHD7
chromodomain helicase DNA binding protein 7
chr1_+_234040547 6.887 NM_173508
SLC35F3
solute carrier family 35, member F3
chrX_-_19905449 6.884 SH3KBP1
SH3-domain kinase binding protein 1
chr12_+_125478151 6.876 NM_080626
BRI3BP
BRI3 binding protein
chr15_+_80987953 6.852 FAM108C1
family with sequence similarity 108, member C1
chr1_+_210406194 6.838 NM_019605
SERTAD4
SERTA domain containing 4
chr6_+_41606193 6.801 NM_005586
MDFI
MyoD family inhibitor
chr14_-_69445978 6.793 ACTN1
actinin, alpha 1
chr8_-_42396617 6.787 SLC20A2
solute carrier family 20 (phosphate transporter), member 2
chr3_+_196295481 6.736 FBXO45
F-box protein 45
chr14_-_69446008 6.713 ACTN1
actinin, alpha 1
chr19_+_16187047 6.691 NM_003290
TPM4
tropomyosin 4
chr1_+_9648931 6.686 NM_001010866
NM_001130924
TMEM201

transmembrane protein 201

chr8_-_133493003 6.670 NM_004519
KCNQ3
potassium voltage-gated channel, KQT-like subfamily, member 3
chr3_+_196295708 6.655 NM_001105573
FBXO45
F-box protein 45
chr11_-_119187811 6.648 NM_006500
MCAM
melanoma cell adhesion molecule
chr1_+_92495484 6.643 NM_173567
EPHX4
epoxide hydrolase 4
chr20_-_56285576 6.625 NM_199169
NM_199170
PMEPA1

prostate transmembrane protein, androgen induced 1

chr1_-_32801606 6.614 NM_023009
MARCKSL1
MARCKS-like 1
chr7_-_28220146 6.604 JAZF1
JAZF zinc finger 1
chr10_+_12391471 6.604 NM_020397
NM_153498
CAMK1D

calcium/calmodulin-dependent protein kinase ID

chr17_+_4402128 6.599 NM_001124758
SPNS2
spinster homolog 2 (Drosophila)
chr3_+_32433342 6.596 CMTM7
CKLF-like MARVEL transmembrane domain containing 7
chr17_+_60705042 6.577 MRC2
mannose receptor, C type 2
chr2_-_227664330 6.575 IRS1
insulin receptor substrate 1
chr9_+_103235489 6.558 NM_003692
TMEFF1
transmembrane protein with EGF-like and two follistatin-like domains 1
chr2_+_173292344 6.543 ITGA6
integrin, alpha 6
chr9_-_131940481 6.524 IER5L
immediate early response 5-like
chr15_-_101792125 6.501 NM_014918
CHSY1
chondroitin sulfate synthase 1
chr1_+_162531349 6.501 UAP1
UDP-N-acteylglucosamine pyrophosphorylase 1
chrX_+_68725077 6.494 NM_015686
FAM155B
family with sequence similarity 155, member B
chr19_-_19006868 6.477 NM_021267
NM_198207
NM_001492
CERS1

GDF1
ceramide synthase 1

growth differentiation factor 1
chr7_+_77166331 6.466 PTPN12
protein tyrosine phosphatase, non-receptor type 12
chr4_+_84457256 6.450 AGPAT9
1-acylglycerol-3-phosphate O-acyltransferase 9
chr1_-_32403975 6.446 NM_080391
PTP4A2
protein tyrosine phosphatase type IVA, member 2
chr15_+_38544119 6.440 SPRED1
sprouty-related, EVH1 domain containing 1
chr5_+_129240453 6.435 NM_175856
CHSY3
chondroitin sulfate synthase 3
chr1_+_229761988 6.424 URB2
URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
chr4_-_1713914 6.421 NM_006527
SLBP
stem-loop binding protein
chr3_-_185542807 6.413 NM_001007225
NM_006548
IGF2BP2

insulin-like growth factor 2 mRNA binding protein 2

chr19_-_1863425 6.405 KLF16
Kruppel-like factor 16
chr5_-_114632240 6.399 NM_001040440
CCDC112
coiled-coil domain containing 112
chr2_-_204399906 6.392 NM_203365
NM_213589
RAPH1

Ras association (RalGDS/AF-6) and pleckstrin homology domains 1

chr20_+_45523247 6.381 NM_005244
NM_172110
EYA2

eyes absent homolog 2 (Drosophila)

chr10_-_92617670 6.380 NM_000872
NM_019859
NM_019860
HTR7


5-hydroxytryptamine (serotonin) receptor 7 (adenylate cyclase-coupled)


chr8_-_38325524 6.377 FGFR1
fibroblast growth factor receptor 1
chr2_+_239756672 6.355 NM_057179
TWIST2
twist homolog 2 (Drosophila)
chr12_-_50100966 6.354


chr9_+_103235634 6.345 TMEFF1
transmembrane protein with EGF-like and two follistatin-like domains 1
chr8_+_61591239 6.337 NM_017780
CHD7
chromodomain helicase DNA binding protein 7

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
1.45 2.22e-13 GO:0071841 cellular component organization or biogenesis at cellular level
1.32 2.68e-13 GO:0044260 cellular macromolecule metabolic process
1.83 3.99e-13 GO:0022008 neurogenesis
1.85 1.11e-12 GO:0048699 generation of neurons
1.44 2.74e-12 GO:0071842 cellular component organization at cellular level
1.37 3.16e-12 GO:0071840 cellular component organization or biogenesis
1.61 5.75e-12 GO:0007399 nervous system development
2.11 8.08e-12 GO:0000904 cell morphogenesis involved in differentiation
1.13 9.52e-12 GO:0009987 cellular process
1.36 1.59e-11 GO:0016043 cellular component organization
1.59 1.92e-11 GO:0009653 anatomical structure morphogenesis
1.52 3.22e-11 GO:0006464 protein modification process
1.96 1.19e-10 GO:0000902 cell morphogenesis
1.48 4.60e-10 GO:0043412 macromolecule modification
1.90 5.87e-10 GO:0032989 cellular component morphogenesis
2.02 9.13e-10 GO:0031175 neuron projection development
1.44 3.07e-09 GO:0048869 cellular developmental process
1.86 3.82e-09 GO:0030030 cell projection organization
1.45 4.46e-09 GO:0030154 cell differentiation
2.07 5.39e-09 GO:0007409 axonogenesis
2.04 8.23e-09 GO:0048667 cell morphogenesis involved in neuron differentiation
2.03 1.01e-08 GO:0048812 neuron projection morphogenesis
2.21 2.57e-08 GO:0060284 regulation of cell development
1.24 3.28e-08 GO:0043170 macromolecule metabolic process
1.34 7.96e-08 GO:0048731 system development
1.92 9.13e-08 GO:0048858 cell projection morphogenesis
1.70 1.05e-07 GO:0051128 regulation of cellular component organization
1.20 1.16e-07 GO:0044237 cellular metabolic process
1.32 1.19e-07 GO:0048856 anatomical structure development
1.65 1.49e-07 GO:0048468 cell development
1.90 1.58e-07 GO:0032990 cell part morphogenesis
1.51 1.74e-07 GO:0009966 regulation of signal transduction
1.30 1.93e-07 GO:0007275 multicellular organismal development
1.47 2.16e-07 GO:0006996 organelle organization
1.19 2.55e-07 GO:0044238 primary metabolic process
1.18 2.79e-07 GO:0050794 regulation of cellular process
1.28 3.34e-07 GO:0032502 developmental process
1.74 4.56e-07 GO:0030182 neuron differentiation
1.35 5.99e-07 GO:0044267 cellular protein metabolic process
1.17 9.40e-07 GO:0050789 regulation of biological process
1.80 1.31e-06 GO:0048666 neuron development
1.44 1.67e-06 GO:0023051 regulation of signaling
1.38 1.76e-06 GO:0048523 negative regulation of cellular process
2.97 2.39e-06 GO:0010720 positive regulation of cell development
1.15 4.73e-06 GO:0065007 biological regulation
2.73 4.84e-06 GO:0006403 RNA localization
2.21 4.95e-06 GO:0050767 regulation of neurogenesis
2.18 8.55e-06 GO:0030036 actin cytoskeleton organization
2.01 9.82e-06 GO:0007411 axon guidance
1.68 1.05e-05 GO:0045595 regulation of cell differentiation
2.06 1.57e-05 GO:0030029 actin filament-based process
1.30 1.58e-05 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.66 1.75e-05 GO:0010769 regulation of cell morphogenesis involved in differentiation
2.77 1.92e-05 GO:0051028 mRNA transport
1.47 2.03e-05 GO:0051641 cellular localization
2.68 2.18e-05 GO:0050657 nucleic acid transport
2.68 2.18e-05 GO:0050658 RNA transport
2.68 2.18e-05 GO:0051236 establishment of RNA localization
2.64 2.26e-05 GO:0022604 regulation of cell morphogenesis
1.16 2.53e-05 GO:0008152 metabolic process
1.33 2.60e-05 GO:0048519 negative regulation of biological process
1.93 3.34e-05 GO:0051301 cell division
2.49 6.11e-05 GO:0015931 nucleobase, nucleoside, nucleotide and nucleic acid transport
1.24 1.13e-04 GO:0023052 signaling
1.51 1.46e-04 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.26 1.48e-04 GO:0006807 nitrogen compound metabolic process
1.97 1.51e-04 GO:0051130 positive regulation of cellular component organization
1.58 2.31e-04 GO:2000026 regulation of multicellular organismal development
1.99 2.43e-04 GO:0051960 regulation of nervous system development
1.52 2.88e-04 GO:0050793 regulation of developmental process
1.60 2.92e-04 GO:0009890 negative regulation of biosynthetic process
1.23 3.62e-04 GO:0031323 regulation of cellular metabolic process
2.50 4.14e-04 GO:0010975 regulation of neuron projection development
1.25 5.77e-04 GO:0034641 cellular nitrogen compound metabolic process
1.62 6.02e-04 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.63 7.26e-04 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.21 7.97e-04 GO:0019222 regulation of metabolic process
2.31 8.50e-04 GO:0031344 regulation of cell projection organization
1.41 9.53e-04 GO:0051239 regulation of multicellular organismal process
1.58 9.58e-04 GO:0031327 negative regulation of cellular biosynthetic process
1.59 1.08e-03 GO:0010558 negative regulation of macromolecule biosynthetic process
1.46 1.10e-03 GO:0007049 cell cycle
1.27 1.26e-03 GO:0048518 positive regulation of biological process
2.10 1.32e-03 GO:0045664 regulation of neuron differentiation
1.23 1.33e-03 GO:0007165 signal transduction
1.60 1.39e-03 GO:0051172 negative regulation of nitrogen compound metabolic process
1.40 1.45e-03 GO:0033036 macromolecule localization
1.33 1.63e-03 GO:0048583 regulation of response to stimulus
1.22 1.77e-03 GO:0080090 regulation of primary metabolic process
1.28 1.82e-03 GO:0048522 positive regulation of cellular process
1.46 1.86e-03 GO:0009892 negative regulation of metabolic process
1.81 1.94e-03 GO:0018193 peptidyl-amino acid modification
1.61 2.23e-03 GO:0000278 mitotic cell cycle
1.48 2.26e-03 GO:0010605 negative regulation of macromolecule metabolic process
2.18 2.31e-03 GO:0051493 regulation of cytoskeleton organization
1.29 3.37e-03 GO:0090304 nucleic acid metabolic process
2.41 3.38e-03 GO:0007265 Ras protein signal transduction
1.24 3.38e-03 GO:0019538 protein metabolic process
1.50 3.40e-03 GO:0022402 cell cycle process
1.42 3.56e-03 GO:0051649 establishment of localization in cell
1.66 3.65e-03 GO:0007010 cytoskeleton organization
1.84 3.87e-03 GO:0022603 regulation of anatomical structure morphogenesis
1.64 3.89e-03 GO:0006935 chemotaxis
1.64 3.89e-03 GO:0042330 taxis
1.22 4.14e-03 GO:0060255 regulation of macromolecule metabolic process
1.25 4.40e-03 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.09 4.56e-03 GO:0006260 DNA replication
1.47 5.19e-03 GO:0031324 negative regulation of cellular metabolic process
1.53 6.76e-03 GO:0009790 embryo development
1.42 6.80e-03 GO:0010646 regulation of cell communication
1.72 7.02e-03 GO:0007264 small GTPase mediated signal transduction
2.08 7.03e-03 GO:0051169 nuclear transport
2.64 7.18e-03 GO:0051168 nuclear export
1.24 7.34e-03 GO:0051171 regulation of nitrogen compound metabolic process
1.67 7.51e-03 GO:0023057 negative regulation of signaling
4.82 7.77e-03 GO:0010718 positive regulation of epithelial to mesenchymal transition
1.67 8.31e-03 GO:0010648 negative regulation of cell communication
1.39 8.33e-03 GO:0044085 cellular component biogenesis
1.53 8.40e-03 GO:0022403 cell cycle phase
1.43 8.79e-03 GO:0006793 phosphorus metabolic process
1.43 8.79e-03 GO:0006796 phosphate metabolic process
1.69 1.00e-02 GO:0009968 negative regulation of signal transduction
1.48 1.05e-02 GO:0046907 intracellular transport
2.91 1.16e-02 GO:0006479 protein methylation
2.91 1.16e-02 GO:0008213 protein alkylation
1.94 1.20e-02 GO:0009154 purine ribonucleotide catabolic process
2.06 1.27e-02 GO:0006913 nucleocytoplasmic transport
1.43 1.29e-02 GO:0032879 regulation of localization
2.25 1.34e-02 GO:0006470 protein dephosphorylation
1.58 1.53e-02 GO:0051253 negative regulation of RNA metabolic process
4.58 1.54e-02 GO:0010770 positive regulation of cell morphogenesis involved in differentiation
1.18 1.57e-02 GO:0051716 cellular response to stimulus
1.92 1.59e-02 GO:0009261 ribonucleotide catabolic process
1.48 1.70e-02 GO:0051173 positive regulation of nitrogen compound metabolic process
1.64 1.82e-02 GO:0008283 cell proliferation
1.58 2.02e-02 GO:0045892 negative regulation of transcription, DNA-dependent
1.91 2.10e-02 GO:0002009 morphogenesis of an epithelium
1.84 2.12e-02 GO:0009166 nucleotide catabolic process
1.83 2.40e-02 GO:0045596 negative regulation of cell differentiation
1.87 2.43e-02 GO:0006195 purine nucleotide catabolic process
1.73 2.82e-02 GO:0045597 positive regulation of cell differentiation
1.24 3.21e-02 GO:0010468 regulation of gene expression
1.53 3.53e-02 GO:0010629 negative regulation of gene expression
3.73 3.89e-02 GO:0043488 regulation of mRNA stability
1.71 3.90e-02 GO:0070647 protein modification by small protein conjugation or removal
1.30 4.31e-02 GO:0034645 cellular macromolecule biosynthetic process
2.11 4.32e-02 GO:0006184 GTP catabolic process
1.46 4.36e-02 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.43 4.94e-02 GO:0040011 locomotion
1.24 4.99e-02 GO:2000112 regulation of cellular macromolecule biosynthetic process

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
1.17 5.24e-24 GO:0044424 intracellular part
1.15 2.59e-20 GO:0005622 intracellular
1.17 1.91e-16 GO:0043229 intracellular organelle
1.17 2.80e-16 GO:0043226 organelle
1.27 7.79e-14 GO:0005634 nucleus
1.54 2.84e-13 GO:0031981 nuclear lumen
1.48 5.12e-13 GO:0044428 nuclear part
1.17 3.43e-12 GO:0043231 intracellular membrane-bounded organelle
1.17 3.53e-12 GO:0043227 membrane-bounded organelle
1.18 9.03e-12 GO:0005737 cytoplasm
1.23 1.26e-10 GO:0044422 organelle part
1.24 1.48e-10 GO:0044446 intracellular organelle part
1.37 6.01e-10 GO:0043228 non-membrane-bounded organelle
1.37 6.01e-10 GO:0043232 intracellular non-membrane-bounded organelle
1.56 8.28e-10 GO:0005654 nucleoplasm
1.39 6.72e-09 GO:0070013 intracellular organelle lumen
1.37 3.42e-08 GO:0031974 membrane-enclosed lumen
1.40 3.50e-08 GO:0005829 cytosol
1.37 3.67e-08 GO:0043233 organelle lumen
1.46 5.26e-08 GO:0005856 cytoskeleton
4.79 2.52e-07 GO:0042641 actomyosin
2.09 3.15e-07 GO:0015629 actin cytoskeleton
1.29 9.14e-07 GO:0043234 protein complex
4.75 7.00e-06 GO:0001725 stress fiber
1.61 1.05e-05 GO:0044451 nucleoplasm part
1.05 1.69e-05 GO:0044464 cell part
1.05 1.76e-05 GO:0005623 cell
2.72 2.12e-05 GO:0019898 extrinsic to membrane
4.44 2.64e-05 GO:0032432 actin filament bundle
1.22 1.14e-04 GO:0032991 macromolecular complex
2.89 4.00e-04 GO:0005643 nuclear pore
2.09 5.17e-04 GO:0031252 cell leading edge
1.42 6.84e-04 GO:0044430 cytoskeletal part
2.12 8.26e-04 GO:0070161 anchoring junction
1.14 8.35e-04 GO:0044444 cytoplasmic part
2.91 1.06e-03 GO:0019897 extrinsic to plasma membrane
1.31 2.83e-03 GO:0012505 endomembrane system
1.53 3.56e-03 GO:0030054 cell junction
2.51 4.63e-03 GO:0046930 pore complex
2.16 4.98e-03 GO:0005938 cell cortex
3.25 5.07e-03 GO:0008287 protein serine/threonine phosphatase complex
2.43 5.70e-03 GO:0001726 ruffle
2.07 6.16e-03 GO:0005912 adherens junction
2.23 1.10e-02 GO:0030055 cell-substrate junction
8.32 1.27e-02 GO:0071204 histone pre-mRNA 3'end processing complex
2.24 1.43e-02 GO:0005924 cell-substrate adherens junction
2.27 1.54e-02 GO:0005925 focal adhesion
2.39 2.37e-02 GO:0009898 internal side of plasma membrane
3.15 2.71e-02 GO:0032587 ruffle membrane
1.54 2.90e-02 GO:0044427 chromosomal part
1.74 4.28e-02 GO:0016323 basolateral plasma membrane
1.50 4.38e-02 GO:0005730 nucleolus
3.18 4.41e-02 GO:0005834 heterotrimeric G-protein complex
2.90 4.43e-02 GO:0031234 extrinsic to internal side of plasma membrane

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
1.29 1.47e-25 GO:0005515 protein binding
1.12 2.51e-13 GO:0005488 binding
1.36 1.71e-07 GO:0000166 nucleotide binding
1.81 2.01e-07 GO:0008092 cytoskeletal protein binding
1.38 2.41e-06 GO:0035639 purine ribonucleoside triphosphate binding
1.38 2.45e-06 GO:0032553 ribonucleotide binding
1.38 2.45e-06 GO:0032555 purine ribonucleotide binding
1.37 2.89e-06 GO:0017076 purine nucleotide binding
1.96 6.92e-06 GO:0003779 actin binding
2.06 2.84e-04 GO:0003924 GTPase activity
1.51 3.12e-04 GO:0003723 RNA binding
2.21 3.99e-04 GO:0004721 phosphoprotein phosphatase activity
2.10 4.30e-04 GO:0003682 chromatin binding
1.44 5.56e-04 GO:0030528 transcription regulator activity
1.32 9.04e-04 GO:0016740 transferase activity
1.73 1.62e-03 GO:0005525 GTP binding
1.49 1.69e-03 GO:0042802 identical protein binding
1.49 1.94e-03 GO:0019899 enzyme binding
1.78 2.84e-03 GO:0016564 transcription repressor activity
1.68 5.17e-03 GO:0019001 guanyl nucleotide binding
1.68 5.17e-03 GO:0032561 guanyl ribonucleotide binding
1.80 1.45e-02 GO:0016791 phosphatase activity
1.30 1.60e-02 GO:0032559 adenyl ribonucleotide binding
1.30 1.65e-02 GO:0030554 adenyl nucleotide binding
3.20 1.97e-02 GO:0050839 cell adhesion molecule binding
8.32 2.14e-02 GO:0031694 alpha-2A adrenergic receptor binding
1.29 2.26e-02 GO:0005524 ATP binding