Motif ID: TFAP2B.p2

Z-value: 2.168


Transcription factors associated with TFAP2B.p2:

Gene SymbolEntrez IDGene Name
TFAP2B 7021 transcription factor AP-2 beta (activating enhancer binding protein 2 beta)

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
TFAP2Bhg19_v1_chr6_+_50786438_50786632-0.422.0e-04Click!


Activity profile for motif TFAP2B.p2.

activity profile for motif TFAP2B.p2


Sorted Z-values histogram for motif TFAP2B.p2

Sorted Z-values for motif TFAP2B.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TFAP2B.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr15_-_65067696 20.064 NM_194272
RBPMS2
RNA binding protein with multiple splicing 2
chr5_+_92920592 15.607 NR2F1
NR2F2
nuclear receptor subfamily 2, group F, member 1
nuclear receptor subfamily 2, group F, member 2
chr19_+_34972866 14.989 NM_001080436
WTIP
Wilms tumor 1 interacting protein
chr4_+_2061238 14.040 NM_178557
NAT8L
N-acetyltransferase 8-like (GCN5-related, putative)
chr4_-_819879 12.925 NM_006651
CPLX1
complexin 1
chr16_+_89989686 11.420 NM_006086
TUBB3
tubulin, beta 3 class III
chr2_+_241375207 11.086 GPC1
glypican 1
chr8_-_29207795 10.270 NM_001394
DUSP4
dual specificity phosphatase 4
chr11_-_61684981 10.157 NM_013401
RAB3IL1
RAB3A interacting protein (rabin3)-like 1
chr10_+_134210691 10.089 NM_001098637
NM_138499
PWWP2B

PWWP domain containing 2B

chr19_+_1753661 9.841 NM_001080488
ONECUT3
one cut homeobox 3
chrX_-_19140581 9.690 NM_001079858
NM_001079859
NM_001079860
NM_001184833
NM_001184834
NM_001184835
NM_001184836
NM_001184837
NM_005756
GPR64








G protein-coupled receptor 64








chr2_+_103236147 9.672 NM_003048
SLC9A2
solute carrier family 9 (sodium/hydrogen exchanger), member 2
chr1_+_23037329 9.481 NM_004442
NM_017449
EPHB2

EPH receptor B2

chr6_+_157802479 9.306 NM_024630
NM_153746
ZDHHC14

zinc finger, DHHC-type containing 14

chr22_+_51113069 9.101 NM_001080420
SHANK3
SH3 and multiple ankyrin repeat domains 3
chr22_-_39639967 9.059 PDGFB
platelet-derived growth factor beta polypeptide
chr20_-_31172874 8.757 LOC284804
uncharacterized LOC284804
chr17_+_81037504 8.754 NM_001004431
METRNL
meteorin, glial cell differentiation regulator-like
chr5_+_72416375 8.718 NM_001161342
NM_173490
TMEM171

transmembrane protein 171

chr7_-_559479 8.668 NM_002607
NM_033023
PDGFA

platelet-derived growth factor alpha polypeptide

chr16_+_89642111 8.631 NM_014427
NM_153636
CPNE7

copine VII

chr7_-_994259 8.607 NM_006869
ADAP1
ArfGAP with dual PH domains 1
chr7_-_994008 8.564 ADAP1
ArfGAP with dual PH domains 1
chr7_-_158380360 8.471 NM_002847
NM_130842
NM_130843
PTPRN2


protein tyrosine phosphatase, receptor type, N polypeptide 2


chr10_-_735522 8.206 NM_014974
DIP2C
DIP2 disco-interacting protein 2 homolog C (Drosophila)
chr7_-_150946031 8.173 SMARCD3
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr4_+_84457256 8.043 AGPAT9
1-acylglycerol-3-phosphate O-acyltransferase 9
chr14_-_101034261 8.017 NM_001159531
BEGAIN
brain-enriched guanylate kinase-associated homolog (rat)
chr12_+_53491448 7.906 IGFBP6
insulin-like growth factor binding protein 6
chr9_-_38069082 7.887 SHB
Src homology 2 domain containing adaptor protein B
chr17_+_77751929 7.808 NM_005189
NM_032647
CBX2

chromobox homolog 2

chr1_-_95392501 7.704 NM_001839
CNN3
calponin 3, acidic
chr15_-_101459410 7.611


chr7_-_994371 7.588 ADAP1
ArfGAP with dual PH domains 1
chr20_-_62680880 7.452 NM_018419
SOX18
SRY (sex determining region Y)-box 18
chr1_-_31381436 7.419 NM_014654
SDC3
syndecan 3
chr17_+_74380676 7.391 NM_001142601
NM_021972
NM_182965
SPHK1


sphingosine kinase 1


chr2_-_86116016 7.362 NM_003896
ST3GAL5
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
chr8_+_136470108 7.287 KHDRBS3
KH domain containing, RNA binding, signal transduction associated 3
chr7_-_150945701 7.271 SMARCD3
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr12_+_65672682 7.246 NM_001193461
MSRB3
methionine sulfoxide reductase B3
chr12_+_65672422 7.243 NM_001031679
NM_001193460
NM_198080
MSRB3


methionine sulfoxide reductase B3


chr7_-_559030 7.205 PDGFA
platelet-derived growth factor alpha polypeptide
chr14_-_105261850 7.201 AKT1
v-akt murine thymoma viral oncogene homolog 1
chrX_+_68725077 7.146 NM_015686
FAM155B
family with sequence similarity 155, member B
chr9_+_138371627 7.127 NM_014811
PPP1R26
protein phosphatase 1, regulatory subunit 26
chr1_-_231175971 7.099 NM_198552
FAM89A
family with sequence similarity 89, member A
chr7_-_150945731 7.056 NM_001003801
SMARCD3
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr1_+_90098693 6.890 LRRC8C
leucine rich repeat containing 8 family, member C
chr17_+_14204326 6.852 NM_006041
HS3ST3B1
heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1
chr12_+_53491417 6.828 NM_002178
IGFBP6
insulin-like growth factor binding protein 6
chr12_+_93964801 6.762 SOCS2
suppressor of cytokine signaling 2
chr7_-_558810 6.688 PDGFA
platelet-derived growth factor alpha polypeptide
chr2_+_75061234 6.643 HK2
hexokinase 2
chr11_-_67141008 6.639 NM_013246
CLCF1
cardiotrophin-like cytokine factor 1
chr11_+_45944155 6.624 GYLTL1B
glycosyltransferase-like 1B
chr22_-_20255614 6.621 NM_023004
RTN4R
reticulon 4 receptor
chr9_-_112083005 6.613 NM_018424
NM_019114
EPB41L4B

erythrocyte membrane protein band 4.1 like 4B

chr3_-_127541160 6.596 NM_007283
MGLL
monoglyceride lipase
chr20_+_59827452 6.546 NM_001794
CDH4
cadherin 4, type 1, R-cadherin (retinal)
chr3_-_127541975 6.545 NM_001003794
MGLL
monoglyceride lipase
chr8_-_141645603 6.542 NM_001164623
NM_012154
EIF2C2

eukaryotic translation initiation factor 2C, 2

chr8_+_136469557 6.494 NM_006558
KHDRBS3
KH domain containing, RNA binding, signal transduction associated 3
chr13_+_113344354 6.425 NM_015205
NM_032189
ATP11A

ATPase, class VI, type 11A

chr14_+_105992930 6.418 NM_025268
TMEM121
transmembrane protein 121
chrX_-_153602998 6.414 NM_001110556
NM_001456
FLNA

filamin A, alpha

chr14_-_95786095 6.413 NM_024734
CLMN
calmin (calponin-like, transmembrane)
chr12_-_117319231 6.403 NM_003806
HRK
harakiri, BCL2 interacting protein (contains only BH3 domain)
chr1_+_211500147 6.340 NM_001033910
TRAF5
TNF receptor-associated factor 5
chr9_-_112083196 6.317 EPB41L4B
erythrocyte membrane protein band 4.1 like 4B
chr4_+_84457390 6.314 NM_032717
AGPAT9
1-acylglycerol-3-phosphate O-acyltransferase 9
chr8_-_133492556 6.300 KCNQ3
potassium voltage-gated channel, KQT-like subfamily, member 3
chr8_-_12612968 6.272 NM_152271
LONRF1
LON peptidase N-terminal domain and ring finger 1
chr21_-_43299407 6.257 NM_001040424
NM_022115
PRDM15

PR domain containing 15

chr19_-_1863425 6.234 KLF16
Kruppel-like factor 16
chr11_+_369723 6.186 NM_178537
B4GALNT4
beta-1,4-N-acetyl-galactosaminyl transferase 4
chr17_+_30813928 6.155 NM_003885
CDK5R1
cyclin-dependent kinase 5, regulatory subunit 1 (p35)
chr16_-_80837878 6.116 NM_152342
CDYL2
chromodomain protein, Y-like 2
chr14_-_102975996 6.074 ANKRD9
ankyrin repeat domain 9
chr8_+_146277830 6.059 C8orf33
chromosome 8 open reading frame 33
chr1_-_212873104 6.024 BATF3
basic leucine zipper transcription factor, ATF-like 3
chr4_+_4861371 5.972 NM_002448
MSX1
msh homeobox 1
chr4_+_3465032 5.971 NM_001164673
NM_173660
DOK7

docking protein 7

chr6_+_41514289 5.968 FOXP4
forkhead box P4
chr22_-_50699938 5.930 NM_002969
MAPK12
mitogen-activated protein kinase 12
chr5_+_176873795 5.919 NM_001174101
NM_030567
PRR7

proline rich 7 (synaptic)

chrX_+_152953751 5.900 NM_001142805
NM_005629
SLC6A8

solute carrier family 6 (neurotransmitter transporter, creatine), member 8

chr19_-_55895602 5.899 NM_001190764
TMEM238
transmembrane protein 238
chr19_-_1237840 5.863 NM_152769
C19orf26
chromosome 19 open reading frame 26
chr6_+_43738177 5.826 VEGFA
vascular endothelial growth factor A
chr15_-_74726000 5.804 NM_001146030
SEMA7A
semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
chr17_+_79989485 5.802 NM_005052
RAC3
ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
chr2_+_170590241 5.792 NM_144711
KLHL23
kelch-like 23 (Drosophila)
chr2_+_109745996 5.739 NM_001099289
SH3RF3
SH3 domain containing ring finger 3
chr15_+_81293286 5.721 NM_022566
MESDC1
mesoderm development candidate 1
chr6_+_1611544 5.718 FOXC1
forkhead box C1
chr6_+_83073954 5.671 NM_001166392
TPBG
trophoblast glycoprotein
chr17_+_74380943 5.670 SPHK1
sphingosine kinase 1
chr8_+_146277789 5.630 NM_023080
C8orf33
chromosome 8 open reading frame 33
chr6_-_45983279 5.622 NM_016929
CLIC5
chloride intracellular channel 5
chr1_-_95392449 5.619 CNN3
calponin 3, acidic
chr1_+_211500166 5.593 TRAF5
TNF receptor-associated factor 5
chr10_+_123922940 5.536 TACC2
transforming, acidic coiled-coil containing protein 2
chr9_-_38069207 5.518 NM_003028
SHB
Src homology 2 domain containing adaptor protein B
chr3_-_45267068 5.504 TMEM158
transmembrane protein 158 (gene/pseudogene)
chr8_+_17354562 5.484 NM_001008539
SLC7A2
solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
chr15_+_38544966 5.475 NM_152594
SPRED1
sprouty-related, EVH1 domain containing 1
chr17_+_30814552 5.474 CDK5R1
cyclin-dependent kinase 5, regulatory subunit 1 (p35)
chr1_+_955536 5.462


chr1_-_1284297 5.438 NM_004421
DVL1
dishevelled, dsh homolog 1 (Drosophila)
chr19_-_1567875 5.431 NM_001174118
NM_203304
MEX3D

mex-3 homolog D (C. elegans)

chr14_+_71108373 5.416 NM_015351
TTC9
tetratricopeptide repeat domain 9
chr15_+_101420004 5.410 NM_000693
ALDH1A3
aldehyde dehydrogenase 1 family, member A3
chr9_+_95947211 5.406 NM_006648
WNK2
WNK lysine deficient protein kinase 2
chr6_+_43738394 5.395 VEGFA
vascular endothelial growth factor A
chr3_-_129325175 5.393 NM_015103
PLXND1
plexin D1
chr20_+_57267818 5.390 NM_024663
NPEPL1
aminopeptidase-like 1
chr9_-_100954883 5.382 NM_052820
CORO2A
coronin, actin binding protein, 2A
chr16_+_86600856 5.366 NM_005251
FOXC2
forkhead box C2 (MFH-1, mesenchyme forkhead 1)
chr6_+_168227485 5.339 NM_001040000
NM_001207008
MLLT4

myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4

chr2_+_102314162 5.334 NM_001242560
NM_004834
NM_145686
NM_001242559
NM_145687
MAP4K4




mitogen-activated protein kinase kinase kinase kinase 4




chr15_+_101420032 5.317 ALDH1A3
aldehyde dehydrogenase 1 family, member A3
chr11_-_61348290 5.303 NM_001252065
NM_004200
SYT7

synaptotagmin VII

chr1_+_955468 5.302 NM_198576
AGRN
agrin
chr6_+_41514133 5.296 NM_001012426
NM_001012427
NM_138457
FOXP4


forkhead box P4


chr17_-_79894967 5.287 NM_006907
NM_153824
PYCR1

pyrroline-5-carboxylate reductase 1

chr14_-_71275732 5.272 NM_033141
MAP3K9
mitogen-activated protein kinase kinase kinase 9
chr9_+_103235634 5.236 TMEFF1
transmembrane protein with EGF-like and two follistatin-like domains 1
chr11_+_289113 5.179 NM_025092
ATHL1
ATH1, acid trehalase-like 1 (yeast)
chr11_+_65082288 5.144 NM_006779
CDC42EP2
CDC42 effector protein (Rho GTPase binding) 2
chr9_-_139948448 5.123 NM_001246
NM_203468
ENTPD2

ectonucleoside triphosphate diphosphohydrolase 2

chr1_+_211499956 5.111 NM_004619
TRAF5
TNF receptor-associated factor 5
chr5_+_167718485 5.104 NM_001161661
NM_001161662
NM_015238
WWC1


WW and C2 domain containing 1


chr1_-_53793583 5.096 LRP8
low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
chr1_+_90098643 5.093 NM_032270
LRRC8C
leucine rich repeat containing 8 family, member C
chr15_-_102030138 5.089 NM_002570
NM_138319
NM_138320
NM_138321
NM_138322
NM_138323
NM_138324
NM_138325
PCSK6







proprotein convertase subtilisin/kexin type 6







chr5_+_142150291 5.064 NM_001135608
NM_015071
ARHGAP26

Rho GTPase activating protein 26

chr7_+_48128738 5.052 NM_003364
UPP1
uridine phosphorylase 1
chr19_-_47922738 5.046 NM_001009813
NM_020160
MEIS3

Meis homeobox 3

chr19_-_47922468 5.041 MEIS3
Meis homeobox 3
chr12_+_133067156 5.026 NM_001142641
FBRSL1
fibrosin-like 1
chrX_+_149531439 5.016 NM_001177465
MAMLD1
mastermind-like domain containing 1
chr11_-_32457059 5.008 NM_000378
NM_024424
NM_024426
WT1


Wilms tumor 1


chr16_-_57836370 4.953 KIFC3
kinesin family member C3
chr21_+_46494433 4.928 NM_001112
NM_001160230
NM_015833
NM_015834
ADARB1



adenosine deaminase, RNA-specific, B1



chr1_-_53793743 4.923 NM_001018054
NM_004631
NM_017522
NM_033300
LRP8



low density lipoprotein receptor-related protein 8, apolipoprotein e receptor



chr17_+_27920479 4.915 NM_152345
ANKRD13B
ankyrin repeat domain 13B
chr11_-_2950593 4.896 NM_003311
PHLDA2
pleckstrin homology-like domain, family A, member 2
chr8_-_11324184 4.895 NM_053279
FAM167A
family with sequence similarity 167, member A
chr19_-_47922339 4.894 MEIS3
Meis homeobox 3
chr7_-_28220146 4.888 JAZF1
JAZF zinc finger 1
chr1_+_2160133 4.887 NM_003036
SKI
v-ski sarcoma viral oncogene homolog (avian)
chr19_+_35521591 4.884 NM_001037
NM_199037
SCN1B

sodium channel, voltage-gated, type I, beta

chr8_+_25042066 4.883 DOCK5
dedicator of cytokinesis 5
chr11_+_128564130 4.882 FLI1
Friend leukemia virus integration 1
chr8_-_133493003 4.861 NM_004519
KCNQ3
potassium voltage-gated channel, KQT-like subfamily, member 3
chr18_-_9614454 4.834 PPP4R1
protein phosphatase 4, regulatory subunit 1
chr5_+_154135029 4.834 LARP1
La ribonucleoprotein domain family, member 1
chr1_-_935469 4.831 NM_001142467
NM_021170
HES4

hairy and enhancer of split 4 (Drosophila)

chr22_-_39640956 4.830 NM_002608
PDGFB
platelet-derived growth factor beta polypeptide
chr5_+_34656482 4.829 RAI14
retinoic acid induced 14
chr6_-_107435635 4.826 NM_001080450
BEND3
BEN domain containing 3
chr3_-_128207366 4.825 NM_001145661
GATA2
GATA binding protein 2
chr8_-_42397048 4.815 NM_006749
SLC20A2
solute carrier family 20 (phosphate transporter), member 2
chr11_+_128563993 4.805 FLI1
Friend leukemia virus integration 1
chr8_-_42396617 4.792 SLC20A2
solute carrier family 20 (phosphate transporter), member 2
chr19_+_18530087 4.785 NM_001009998
NM_032627
SSBP4

single stranded DNA binding protein 4

chr3_+_127347966 4.768 NM_015720
PODXL2
podocalyxin-like 2
chr16_+_88772884 4.767 NM_001012759
NM_001012762
CTU2

cytosolic thiouridylase subunit 2 homolog (S. pombe)

chr10_+_123923104 4.750 NM_006997
NM_206860
TACC2

transforming, acidic coiled-coil containing protein 2

chr19_-_7990974 4.740 NM_206833
CTXN1
cortexin 1
chr22_+_45064323 4.722 NM_001017528
NM_001017529
PRR5

proline rich 5 (renal)

chr15_-_101792125 4.722 NM_014918
CHSY1
chondroitin sulfate synthase 1
chr19_-_55628780 4.722 NM_017607
PPP1R12C
protein phosphatase 1, regulatory subunit 12C
chr22_-_50699687 4.720 MAPK12
mitogen-activated protein kinase 12
chr13_+_21277481 4.720 NM_138284
IL17D
interleukin 17D
chr1_+_64239566 4.718 NM_001083592
NM_005012
ROR1

receptor tyrosine kinase-like orphan receptor 1

chr8_-_29206321 4.707 NM_057158
DUSP4
dual specificity phosphatase 4
chr6_+_151561653 4.688 AKAP12
A kinase (PRKA) anchor protein 12
chr1_+_955609 4.687 AGRN
agrin
chr17_+_30814708 4.679


chr1_+_27153130 4.679 NM_032283
ZDHHC18
zinc finger, DHHC-type containing 18
chr19_+_18530423 4.674


chr19_+_30302861 4.668 NM_001238
CCNE1
cyclin E1
chr16_-_22385596 4.665 NM_001802
CDR2
cerebellar degeneration-related protein 2, 62kDa
chr16_-_57836380 4.665 NM_001130100
NM_005550
KIFC3

kinesin family member C3

chr19_+_33685489 4.664 NM_002333
LRP3
low density lipoprotein receptor-related protein 3
chr12_-_93964636 4.663


chr5_+_34656367 4.650 NM_001145522
NM_015577
RAI14

retinoic acid induced 14

chr19_-_46295647 4.648 DMWD
dystrophia myotonica, WD repeat containing
chr6_+_1390068 4.639 NM_001452
FOXF2
forkhead box F2
chr22_+_31031672 4.638 NM_001001479
SLC35E4
solute carrier family 35, member E4
chr1_-_202113855 4.620 NM_138795
ARL8A
ADP-ribosylation factor-like 8A
chr1_-_935352 4.611 HES4
hairy and enhancer of split 4 (Drosophila)
chr9_+_133971902 4.602 AIF1L
allograft inflammatory factor 1-like
chr2_+_85766100 4.600 NM_005911
MAT2A
methionine adenosyltransferase II, alpha
chr1_+_1407158 4.599 NM_031921
ATAD3B
ATPase family, AAA domain containing 3B
chr4_+_3768295 4.587 NM_000683
ADRA2C
adrenergic, alpha-2C-, receptor
chr19_+_18530211 4.574 SSBP4
single stranded DNA binding protein 4

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
1.66 6.40e-11 GO:0009966 regulation of signal transduction
1.59 2.92e-10 GO:0023051 regulation of signaling
1.21 5.12e-09 GO:0050794 regulation of cellular process
1.51 1.19e-06 GO:0009653 anatomical structure morphogenesis
1.92 3.34e-06 GO:0000904 cell morphogenesis involved in differentiation
1.44 3.65e-06 GO:0048583 regulation of response to stimulus
1.17 6.14e-06 GO:0050789 regulation of biological process
1.81 7.90e-06 GO:0000902 cell morphogenesis
1.68 9.91e-06 GO:0051128 regulation of cellular component organization
1.34 1.22e-05 GO:0048518 positive regulation of biological process
1.77 1.62e-05 GO:0032989 cellular component morphogenesis
1.41 1.83e-05 GO:0043412 macromolecule modification
1.64 2.31e-05 GO:0048699 generation of neurons
1.62 2.50e-05 GO:0022008 neurogenesis
2.10 3.22e-05 GO:0060284 regulation of cell development
1.41 3.36e-05 GO:0006464 protein modification process
2.21 9.81e-05 GO:0050767 regulation of neurogenesis
1.34 1.01e-04 GO:0048522 positive regulation of cellular process
2.11 1.22e-04 GO:0071900 regulation of protein serine/threonine kinase activity
1.15 1.22e-04 GO:0065007 biological regulation
2.11 1.52e-04 GO:0051960 regulation of nervous system development
1.35 3.25e-04 GO:0048523 negative regulation of cellular process
4.58 4.63e-04 GO:0001837 epithelial to mesenchymal transition
1.17 4.87e-04 GO:0044237 cellular metabolic process
1.09 5.37e-04 GO:0009987 cellular process
1.42 5.44e-04 GO:0007399 nervous system development
1.52 5.60e-04 GO:0032268 regulation of cellular protein metabolic process
2.81 5.92e-04 GO:0010720 positive regulation of cell development
2.14 7.15e-04 GO:0001558 regulation of cell growth
1.25 7.77e-04 GO:0031323 regulation of cellular metabolic process
1.31 8.32e-04 GO:0044249 cellular biosynthetic process
1.64 8.73e-04 GO:0045595 regulation of cell differentiation
1.32 8.83e-04 GO:0048519 negative regulation of biological process
1.52 1.00e-03 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.49 1.06e-03 GO:0051246 regulation of protein metabolic process
1.74 1.23e-03 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.25 1.30e-03 GO:0007165 signal transduction
1.75 1.64e-03 GO:0031175 neuron projection development
1.41 1.70e-03 GO:0065009 regulation of molecular function
1.16 2.09e-03 GO:0044238 primary metabolic process
1.91 2.39e-03 GO:0045597 positive regulation of cell differentiation
1.20 2.69e-03 GO:0044260 cellular macromolecule metabolic process
2.38 2.91e-03 GO:0031344 regulation of cell projection organization
1.62 2.92e-03 GO:0010558 negative regulation of macromolecule biosynthetic process
1.22 2.95e-03 GO:0019222 regulation of metabolic process
1.65 3.10e-03 GO:0010629 negative regulation of gene expression
1.61 3.40e-03 GO:0031327 negative regulation of cellular biosynthetic process
1.24 3.73e-03 GO:0071840 cellular component organization or biogenesis
1.51 3.88e-03 GO:0050793 regulation of developmental process
1.59 5.04e-03 GO:0009890 negative regulation of biosynthetic process
1.85 5.13e-03 GO:0018193 peptidyl-amino acid modification
2.14 5.13e-03 GO:0043405 regulation of MAP kinase activity
1.75 5.24e-03 GO:0051094 positive regulation of developmental process
1.32 5.74e-03 GO:0030154 cell differentiation
1.61 5.89e-03 GO:0030030 cell projection organization
1.67 6.04e-03 GO:0045892 negative regulation of transcription, DNA-dependent
1.47 6.10e-03 GO:0043067 regulation of programmed cell death
2.88 6.50e-03 GO:0050769 positive regulation of neurogenesis
1.47 6.65e-03 GO:0006793 phosphorus metabolic process
1.47 6.65e-03 GO:0006796 phosphate metabolic process
1.28 6.93e-03 GO:0009058 biosynthetic process
1.23 7.06e-03 GO:0080090 regulation of primary metabolic process
1.66 7.41e-03 GO:0051253 negative regulation of RNA metabolic process
1.60 7.56e-03 GO:0007167 enzyme linked receptor protein signaling pathway
1.61 7.63e-03 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
1.73 7.85e-03 GO:0048812 neuron projection morphogenesis
1.31 7.95e-03 GO:0048869 cellular developmental process
1.45 9.12e-03 GO:0010941 regulation of cell death
2.45 9.24e-03 GO:0010975 regulation of neuron projection development
2.11 9.79e-03 GO:0045664 regulation of neuron differentiation
1.52 1.00e-02 GO:0044093 positive regulation of molecular function
1.49 1.01e-02 GO:0048468 cell development
2.04 1.13e-02 GO:0048011 nerve growth factor receptor signaling pathway
1.98 1.23e-02 GO:0046578 regulation of Ras protein signal transduction
1.23 1.25e-02 GO:0016043 cellular component organization
1.85 1.26e-02 GO:0051098 regulation of binding
1.13 1.30e-02 GO:0008152 metabolic process
2.41 1.33e-02 GO:0010769 regulation of cell morphogenesis involved in differentiation
1.44 1.37e-02 GO:0010646 regulation of cell communication
1.73 1.56e-02 GO:0040008 regulation of growth
1.45 1.59e-02 GO:0042981 regulation of apoptosis
2.39 1.59e-02 GO:0022604 regulation of cell morphogenesis
1.38 1.88e-02 GO:0035556 intracellular signal transduction
1.75 1.90e-02 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
1.65 2.06e-02 GO:0051338 regulation of transferase activity
1.77 2.08e-02 GO:0051056 regulation of small GTPase mediated signal transduction
1.56 2.13e-02 GO:0042325 regulation of phosphorylation
1.21 2.43e-02 GO:0023052 signaling
1.54 2.49e-02 GO:0019220 regulation of phosphate metabolic process
1.54 2.49e-02 GO:0051174 regulation of phosphorus metabolic process
1.53 2.58e-02 GO:0006468 protein phosphorylation
1.59 2.82e-02 GO:0042060 wound healing
1.69 3.07e-02 GO:0048667 cell morphogenesis involved in neuron differentiation
1.22 3.10e-02 GO:0060255 regulation of macromolecule metabolic process
1.51 3.15e-02 GO:2000026 regulation of multicellular organismal development
1.70 3.33e-02 GO:0007409 axonogenesis
1.50 3.38e-02 GO:0031399 regulation of protein modification process
2.42 3.43e-02 GO:0035023 regulation of Rho protein signal transduction
1.64 3.56e-02 GO:0043549 regulation of kinase activity
2.14 3.70e-02 GO:0071902 positive regulation of protein serine/threonine kinase activity
1.56 4.29e-02 GO:0001932 regulation of protein phosphorylation
1.58 4.80e-02 GO:0048666 neuron development

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
1.14 6.45e-15 GO:0044424 intracellular part
1.21 4.12e-14 GO:0005737 cytoplasm
1.13 5.00e-14 GO:0005622 intracellular
1.13 3.52e-08 GO:0043226 organelle
1.13 5.64e-08 GO:0043229 intracellular organelle
1.15 1.80e-07 GO:0043227 membrane-bounded organelle
1.15 1.85e-07 GO:0043231 intracellular membrane-bounded organelle
5.04 1.43e-06 GO:0042641 actomyosin
1.19 2.22e-06 GO:0044444 cytoplasmic part
2.63 3.35e-06 GO:0005912 adherens junction
2.49 7.82e-06 GO:0070161 anchoring junction
1.37 1.05e-05 GO:0005829 cytosol
1.19 2.55e-05 GO:0005634 nucleus
2.81 3.02e-05 GO:0030055 cell-substrate junction
2.82 4.33e-05 GO:0005924 cell-substrate adherens junction
4.89 5.82e-05 GO:0001725 stress fiber
4.56 1.73e-04 GO:0032432 actin filament bundle
2.77 1.80e-04 GO:0005925 focal adhesion
1.17 4.23e-04 GO:0044422 organelle part
1.17 5.50e-04 GO:0044446 intracellular organelle part
1.60 1.27e-03 GO:0030054 cell junction
1.04 2.02e-03 GO:0044464 cell part
1.04 2.09e-03 GO:0005623 cell
1.96 2.61e-03 GO:0016323 basolateral plasma membrane
1.31 3.72e-03 GO:0031981 nuclear lumen
1.27 9.58e-03 GO:0044428 nuclear part
1.41 1.28e-02 GO:0005794 Golgi apparatus
1.31 1.31e-02 GO:0012505 endomembrane system
1.59 1.60e-02 GO:0000139 Golgi membrane
3.44 1.91e-02 GO:0032587 ruffle membrane
1.52 2.43e-02 GO:0044431 Golgi apparatus part
1.97 2.51e-02 GO:0031252 cell leading edge
2.42 3.01e-02 GO:0001726 ruffle
1.24 3.20e-02 GO:0070013 intracellular organelle lumen
1.90 3.62e-02 GO:0005911 cell-cell junction
9.78 4.77e-02 GO:0042405 nuclear inclusion body

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
1.20 5.63e-10 GO:0005515 protein binding
1.47 1.39e-07 GO:0016740 transferase activity
1.09 3.88e-06 GO:0005488 binding
1.54 1.69e-04 GO:0016772 transferase activity, transferring phosphorus-containing groups
1.58 1.78e-04 GO:0016301 kinase activity
1.60 2.28e-04 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.59 2.55e-04 GO:0019899 enzyme binding
1.67 7.52e-04 GO:0008092 cytoskeletal protein binding
1.73 1.16e-03 GO:0019904 protein domain specific binding
1.86 2.41e-03 GO:0016564 transcription repressor activity
1.70 3.08e-03 GO:0004674 protein serine/threonine kinase activity
1.57 6.37e-03 GO:0004672 protein kinase activity
1.30 7.22e-03 GO:0035639 purine ribonucleoside triphosphate binding
1.30 8.12e-03 GO:0032553 ribonucleotide binding
1.30 8.12e-03 GO:0032555 purine ribonucleotide binding
1.30 8.55e-03 GO:0017076 purine nucleotide binding
9.78 8.71e-03 GO:0008526 phosphatidylinositol transporter activity
1.32 2.26e-02 GO:0030554 adenyl nucleotide binding
1.32 2.32e-02 GO:0032559 adenyl ribonucleotide binding
1.32 2.72e-02 GO:0005524 ATP binding
1.14 2.77e-02 GO:0003824 catalytic activity
1.24 4.39e-02 GO:0000166 nucleotide binding