Motif ID: TEAD1.p2

Z-value: 1.481


Transcription factors associated with TEAD1.p2:

Gene SymbolEntrez IDGene Name
TEAD1 7003 TEA domain family member 1 (SV40 transcriptional enhancer factor)
TEAD2 8463 TEA domain family member 2
TEAD3 7005 TEAD3 TEA domain family member 3
TEAD4 7004 TEAD4 TEA domain family member 4

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
TEAD1hg19_v1_chr11_+_12695851_126960760.447.1e-05Click!
TEAD3hg19_v1_chr6_-_35464716_354649080.449.5e-05Click!
TEAD4hg19_v1_chr12_+_3068989_3069134-0.334.0e-03Click!
TEAD2hg19_v1_chr19_-_49865638_498657130.084.7e-01Click!


Activity profile for motif TEAD1.p2.

activity profile for motif TEAD1.p2


Sorted Z-values histogram for motif TEAD1.p2

Sorted Z-values for motif TEAD1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TEAD1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_-_132272311 21.332 NM_001901
 CTGF
connective tissue growth factor
chr12_-_7245006 12.817 NM_001733
 C1R
complement component 1, r subcomponent
chr8_-_108510094 12.147 NM_001146
NM_001199859
 ANGPT1

angiopoietin 1

chr5_-_151066492 11.374 NM_003118
 SPARC
secreted protein, acidic, cysteine-rich (osteonectin)
chr5_-_151066445 10.559 SPARC
secreted protein, acidic, cysteine-rich (osteonectin)
chr12_-_7245048 10.352 C1R
complement component 1, r subcomponent
chr3_-_112359863 10.083 CCDC80
coiled-coil domain containing 80
chr3_+_190105660 9.927 NM_006580
 CLDN16
claudin 16
chr3_-_112359962 9.772 NM_199511
NM_199512
 CCDC80

coiled-coil domain containing 80

chr16_+_15528324 9.725 NM_033201
 C16orf45
chromosome 16 open reading frame 45
chr3_-_112359660 9.492 CCDC80
coiled-coil domain containing 80
chr3_-_112359565 9.250 CCDC80
coiled-coil domain containing 80
chr14_+_76044939 9.225 NM_017791
 FLVCR2
feline leukemia virus subgroup C cellular receptor family, member 2
chr2_+_228029280 9.224 NM_000091
 COL4A3
collagen, type IV, alpha 3 (Goodpasture antigen)
chr3_-_112359277 9.208 CCDC80
coiled-coil domain containing 80
chr3_-_112359547 9.103 CCDC80
coiled-coil domain containing 80
chr3_-_112359251 9.050 CCDC80
coiled-coil domain containing 80
chr3_-_112359443 8.994 CCDC80
coiled-coil domain containing 80
chr2_-_216246961 8.929 FN1
fibronectin 1
chr4_-_186733372 8.573 NM_003603
NM_001145670
 SORBS2

sorbin and SH3 domain containing 2

chr7_-_142985270 8.557


chrX_-_13397504 8.384


chr10_+_99344421 8.328 HOGA1
4-hydroxy-2-oxoglutarate aldolase 1
chr5_-_39424930 8.324 DAB2
disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
chr14_+_95047730 7.706 NM_000624
 SERPINA5
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
chr9_+_91150015 7.427 NM_001161625
NM_145283
 NXNL2

nucleoredoxin-like 2

chr12_-_96184510 7.231 NM_021229
 NTN4
netrin 4
chr1_-_214724844 6.984 PTPN14
protein tyrosine phosphatase, non-receptor type 14
chr10_-_90712510 6.721 NM_001613
 ACTA2
actin, alpha 2, smooth muscle, aorta
chr10_-_99446899 6.591 NM_021732
 AVPI1
arginine vasopressin-induced 1
chr2_-_192711923 6.460 NM_004657
 SDPR
serum deprivation response
chr2_-_192711651 6.330 SDPR
serum deprivation response
chr17_-_45899133 5.809 NM_145798
 OSBPL7
oxysterol binding protein-like 7
chr4_-_186578122 5.801 NM_001145674
NM_001145675
 SORBS2

sorbin and SH3 domain containing 2

chr19_+_12075868 5.769 NM_001012753
 ZNF763
zinc finger protein 763
chr7_+_73245192 5.668 NM_001305
 CLDN4
claudin 4
chr6_-_134496833 5.608 SGK1
serum/glucocorticoid regulated kinase 1
chr15_-_69707358 5.506 LOC145694
uncharacterized LOC145694
chrX_-_114797017 5.460


chr6_-_30899926 5.370 NM_205854
 SFTA2
surfactant associated 2
chr1_-_214724974 5.237 NM_005401
 PTPN14
protein tyrosine phosphatase, non-receptor type 14
chr17_-_45899118 5.212 OSBPL7
oxysterol binding protein-like 7
chr6_-_134497069 5.207 NM_001143678
 SGK1
serum/glucocorticoid regulated kinase 1
chr15_-_48937795 5.000 NM_000138
 FBN1
fibrillin 1
chr16_+_4838397 4.947 NM_001253790
NM_001253791
 LOC440335

uncharacterized LOC440335

chr1_-_12677347 4.847 NM_004753
 DHRS3
dehydrogenase/reductase (SDR family) member 3
chr12_+_53442732 4.830 NM_015319
 TENC1
tensin like C1 domain containing phosphatase (tensin 2)
chr3_-_12586962 4.821 NM_001195279
 LOC100129480
uncharacterized LOC100129480
chr17_+_9729380 4.774 NM_004246
 GLP2R
glucagon-like peptide 2 receptor
chr11_+_114166534 4.703 NM_006169
 NNMT
nicotinamide N-methyltransferase
chr3_-_149086884 4.673 TM4SF1
transmembrane 4 L six family member 1
chr5_-_39425297 4.617 NM_001244871
NM_001343
 DAB2

disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)

chr1_-_3447974 4.582 MEGF6
multiple EGF-like-domains 6
chr16_+_29823408 4.579 NM_145239
 PRRT2
proline-rich transmembrane protein 2
chr1_+_78354199 4.541 NM_001172309
NM_144573
 NEXN

nexilin (F actin binding protein)

chr9_+_130911731 4.498 NM_005564
 LCN2
lipocalin 2
chr2_-_20212408 4.398 MATN3
matrilin 3
chr10_+_91087601 4.326 NM_001549
 IFIT3
interferon-induced protein with tetratricopeptide repeats 3
chr2_-_228029274 4.236 NM_000092
 COL4A4
collagen, type IV, alpha 4
chr1_-_92351476 4.185 TGFBR3
transforming growth factor, beta receptor III
chr5_-_39425030 4.011 DAB2
disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
chr2_+_152214105 3.998 NM_007115
 TNFAIP6
tumor necrosis factor, alpha-induced protein 6
chr5_+_42565562 3.991 NM_001242406
 GHR
growth hormone receptor
chr10_+_99344079 3.929 NM_001134670
NM_138413
 HOGA1

4-hydroxy-2-oxoglutarate aldolase 1

chr1_+_164528586 3.904 NM_001204961
NM_001204963
NM_002585
 PBX1


pre-B-cell leukemia homeobox 1


chr6_+_10521564 3.897 NM_145649
 GCNT2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
chr10_+_104155431 3.862 NM_002502
 NFKB2
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr2_-_20212448 3.849 NM_002381
 MATN3
matrilin 3
chr2_+_220436953 3.819 NM_002191
 INHA
inhibin, alpha
chr2_+_237478379 3.729 NM_020311
 CXCR7
chemokine (C-X-C motif) receptor 7
chr15_+_63335086 3.725 TPM1
tropomyosin 1 (alpha)
chr16_-_47495095 3.671 ITFG1
integrin alpha FG-GAP repeat containing 1
chr11_+_2924504 3.644 SLC22A18
solute carrier family 22, member 18
chr2_+_102803432 3.561 NM_003854
 IL1RL2
interleukin 1 receptor-like 2
chr6_+_126111782 3.546 NM_001122842
NM_001199621
NM_181782
 NCOA7


nuclear receptor coactivator 7


chr1_+_150521786 3.476 NM_019032
NM_025008
 ADAMTSL4

ADAMTS-like 4

chr16_+_29823557 3.459 PRRT2
proline-rich transmembrane protein 2
chr1_+_104159953 3.375 NM_000699
 AMY2A
amylase, alpha 2A (pancreatic)
chr10_-_21186530 3.316 NM_006393
 NEBL
nebulette
chr2_+_157291979 3.267 GPD2
glycerol-3-phosphate dehydrogenase 2 (mitochondrial)
chr3_+_141087298 3.236 ZBTB38
zinc finger and BTB domain containing 38
chr3_+_28431986 3.229 NM_001040432
 ZCWPW2
zinc finger, CW type with PWWP domain 2
chr16_+_47495225 3.203 PHKB
phosphorylase kinase, beta
chr6_-_75915566 3.200 NM_004370
NM_080645
 COL12A1

collagen, type XII, alpha 1

chr9_+_123884043 3.184 CNTRL
centriolin
chr15_+_39873276 3.161 NM_003246
 THBS1
thrombospondin 1
chr6_+_73972878 3.146


chr17_-_4693595 3.136 LOC284014
uncharacterized LOC284014
chrX_+_70315637 3.135 NM_001170931
NM_005938
 FOXO4

forkhead box O4

chr3_-_20053618 3.135 NM_001252657
 PP2D1
protein phosphatase 2C-like domain containing 1
chrX_+_53111482 3.128 NM_022117
 TSPYL2
TSPY-like 2
chr16_+_70207927 3.125 NM_173619
 CLEC18C
CLEC18A
C-type lectin domain family 18, member C
C-type lectin domain family 18, member A
chr1_-_92351613 3.113 NM_001195683
NM_003243
 TGFBR3

transforming growth factor, beta receptor III

chr1_+_86046434 3.070 NM_001554
 CYR61
cysteine-rich, angiogenic inducer, 61
chr11_-_6341708 3.058 NM_145040
 PRKCDBP
protein kinase C, delta binding protein
chr11_-_61100444 3.040 DDB1
damage-specific DNA binding protein 1, 127kDa
chr17_-_15523017 3.023 NM_006382
 CDRT1
CMT1A duplicated region transcript 1
chr15_+_63334753 3.004 NM_000366
NM_001018004
NM_001018005
NM_001018006
NM_001018007
NM_001018020
 TPM1





tropomyosin 1 (alpha)





chr16_+_69984809 2.947 NM_182619
 CLEC18C
CLEC18A
C-type lectin domain family 18, member C
C-type lectin domain family 18, member A
chr6_+_108881010 2.930 NM_201559
 FOXO3
forkhead box O3
chr19_+_16254454 2.926 HSH2D
hematopoietic SH2 domain containing
chr12_+_13153337 2.913 HTR7P1
5-hydroxytryptamine (serotonin) receptor 7 pseudogene 1
chr12_-_15815073 2.907 EPS8
epidermal growth factor receptor pathway substrate 8
chr6_+_123109970 2.899 NM_006714
 SMPDL3A
sphingomyelin phosphodiesterase, acid-like 3A
chr17_-_73663221 2.851 NM_001003715
NM_001003716
NM_004259
 RECQL5


RecQ protein-like 5


chr17_+_72429835 2.845 NM_018653
 GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr17_-_56606534 2.819 SEPT4
septin 4
chr2_+_157291951 2.799 NM_001083112
 GPD2
glycerol-3-phosphate dehydrogenase 2 (mitochondrial)
chr6_-_143266283 2.782 NM_006734
 HIVEP2
human immunodeficiency virus type I enhancer binding protein 2
chr17_-_67057046 2.774 NM_080283
 ABCA9
ATP-binding cassette, sub-family A (ABC1), member 9
chr2_-_157186681 2.769 NR4A2
nuclear receptor subfamily 4, group A, member 2
chr11_-_118436591 2.767 NM_001168618
NM_020153
 IFT46

intraflagellar transport 46 homolog (Chlamydomonas)

chr1_+_111772332 2.751 NM_001025199
 CHI3L2
chitinase 3-like 2
chr12_-_122240827 2.747


chr20_+_33146500 2.696 NM_032514
 MAP1LC3A
microtubule-associated protein 1 light chain 3 alpha
chr12_+_52445185 2.687 NM_002135
NM_173157
 NR4A1

nuclear receptor subfamily 4, group A, member 1

chr16_+_47495166 2.614 NM_000293
NM_001031835
 PHKB

phosphorylase kinase, beta

chr10_-_62149487 2.614 NM_020987
 ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr6_+_126112057 2.554 NCOA7
nuclear receptor coactivator 7
chr3_+_195447810 2.541 MUC20
mucin 20, cell surface associated
chr20_+_35169897 2.527 MYL9
myosin, light chain 9, regulatory
chr1_-_149908721 2.511 MTMR11
myotubularin related protein 11
chr4_+_123091757 2.511 NM_015312
 KIAA1109
KIAA1109
chr12_-_58240746 2.504 NM_005730
 CTDSP2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
chr12_-_122839015 2.479 CLIP1
CAP-GLY domain containing linker protein 1
chr11_-_46939908 2.463 NM_002334
 LRP4
low density lipoprotein receptor-related protein 4
chr15_+_42696957 2.433 NM_173089
NM_173090
 CAPN3

calpain 3, (p94)

chr1_+_61547625 2.426 NM_001134673
NM_005595
 NFIA

nuclear factor I/A

chr1_+_145524989 2.414 NM_003637
 ITGA10
integrin, alpha 10
chr7_+_74379079 2.412 NM_001145063
 GATSL1
GATSL2
GATS protein-like 1
GATS protein-like 2
chr6_+_5085719 2.410 NM_001145115
 PPP1R3G
protein phosphatase 1, regulatory subunit 3G
chr20_+_35169876 2.399 NM_006097
NM_181526
 MYL9

myosin, light chain 9, regulatory

chr3_-_49460110 2.389 NM_000481
NM_001164710
NM_001164711
NM_001164712
 AMT



aminomethyltransferase



chr19_-_4517715 2.371 NM_001080400
 PLIN4
perilipin 4
chr2_-_190044330 2.367 NM_000393
 COL5A2
collagen, type V, alpha 2
chr1_+_27561006 2.357 NM_015023
 WDTC1
WD and tetratricopeptide repeats 1
chr16_-_31146992 2.342 PRSS8
protease, serine, 8
chr17_-_42466840 2.336 NM_000419
 ITGA2B
integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
chr1_-_149908759 2.330 NM_001145862
 MTMR11
myotubularin related protein 11
chr6_+_123110345 2.321 SMPDL3A
sphingomyelin phosphodiesterase, acid-like 3A
chr19_+_1524072 2.320 NM_001243079
 PLK5
polo-like kinase 5
chr11_+_308106 2.318 NM_006435
 IFITM2
interferon induced transmembrane protein 2 (1-8D)
chr14_+_65878579 2.308 FUT8
fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
chr16_-_31147062 2.274 NM_002773
 PRSS8
protease, serine, 8
chr7_+_39773165 2.274 LINC00265
long intergenic non-protein coding RNA 265
chr6_+_30850693 2.265 DDR1
discoidin domain receptor tyrosine kinase 1
chr5_-_19988293 2.263 NM_001167667
NM_004934
 CDH18

cadherin 18, type 2

chr6_-_75915753 2.262 COL12A1
collagen, type XII, alpha 1
chr5_+_121465214 2.249 NM_207317
 ZNF474
zinc finger protein 474
chr14_-_21271002 2.248 NM_002933
NM_198234
NM_198235
 RNASE1


ribonuclease, RNase A family, 1 (pancreatic)


chr1_-_109935869 2.225 NM_001205228
 SORT1
sortilin 1
chr10_+_123872440 2.179 TACC2
transforming, acidic coiled-coil containing protein 2
chr1_+_183155361 2.162 LAMC2
laminin, gamma 2
chr8_-_116681253 2.161 TRPS1
trichorhinophalangeal syndrome I
chr3_-_9994057 2.151 NM_207351
 PRRT3
proline-rich transmembrane protein 3
chr19_-_46974663 2.137 PNMAL1
PNMA-like 1
chr12_-_47219734 2.103 NM_001143824
NM_018018
 SLC38A4

solute carrier family 38, member 4

chr12_+_498513 2.090 NM_001130147
NM_001130148
 CCDC77

coiled-coil domain containing 77

chr6_+_31543340 2.074 NM_000594
 TNF
tumor necrosis factor
chr7_-_100881030 2.073 NM_014343
 CLDN15
claudin 15
chr4_-_89744154 2.071 NM_001015045
 FAM13A
family with sequence similarity 13, member A
chr22_-_43117270 2.057 A4GALT
alpha 1,4-galactosyltransferase
chr19_+_36359346 2.048 NM_001024807
NM_005166
 APLP1

amyloid beta (A4) precursor-like protein 1

chr19_-_41220977 2.042 ADCK4
aarF domain containing kinase 4
chr14_-_23445885 2.018 AJUBA
ajuba LIM protein
chr2_+_210444364 2.003 NM_002374
NM_031845
NM_031847
 MAP2


microtubule-associated protein 2


chr1_-_155006235 2.003 NM_144622
 DCST2
DC-STAMP domain containing 2
chr1_+_183155173 2.003 NM_005562
NM_018891
 LAMC2

laminin, gamma 2

chr4_-_186577858 1.999 SORBS2
sorbin and SH3 domain containing 2
chr19_-_41220992 1.988 NM_001142555
 ADCK4
aarF domain containing kinase 4
chr8_+_145066886 1.986 GRINA
glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
chr15_+_42566365 1.958 NM_198141
 GANC
glucosidase, alpha; neutral C
chr11_+_19372270 1.955 NM_001111018
 NAV2
neuron navigator 2
chrX_-_53310748 1.954 NM_001243197
NM_015075
 IQSEC2

IQ motif and Sec7 domain 2

chr14_-_93651259 1.951 MOAP1
modulator of apoptosis 1
chr3_-_134093235 1.938 NM_016201
 AMOTL2
angiomotin like 2
chr17_-_8079607 1.933 NM_032354
NM_183065
 TMEM107

transmembrane protein 107

chr3_+_38347426 1.910 NM_004803
 SLC22A14
solute carrier family 22, member 14
chr18_+_21032786 1.877 NM_003831
 RIOK3
RIO kinase 3 (yeast)
chr1_+_183155393 1.866 LAMC2
laminin, gamma 2
chr10_+_24498088 1.856 KIAA1217
KIAA1217
chr15_+_96869156 1.833 NM_001145155
 NR2F2
nuclear receptor subfamily 2, group F, member 2
chr7_-_143956720 1.818 NM_001005328
 OR2A7
olfactory receptor, family 2, subfamily A, member 7
chr19_-_11529948 1.817 NM_001035223
NM_001161616
 RGL3

ral guanine nucleotide dissociation stimulator-like 3

chrX_+_2670092 1.815 NM_001141919
NM_001141920
NM_175569
 XGPY2
XG


Xg pseudogene, Y-linked 2
Xg blood group


chrX_-_153141398 1.813 NM_000425
NM_001143963
NM_024003
 L1CAM


L1 cell adhesion molecule


chr2_+_67624431 1.809 NM_019002
 ETAA1
Ewing tumor-associated antigen 1
chr3_-_105421044 1.805 CBLB
Cas-Br-M (murine) ecotropic retroviral transforming sequence b
chr9_-_86153048 1.786 NM_001244959
NM_174938
 FRMD3

FERM domain containing 3

chr1_+_51435911 1.758 CDKN2C
cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
chr7_+_94539209 1.757 NM_001166161
NM_001166162
NM_001166163
 PPP1R9A


protein phosphatase 1, regulatory subunit 9A


chr18_+_21033263 1.751 RIOK3
RIO kinase 3 (yeast)
chr17_+_18647325 1.741 NM_031456
 FBXW10
F-box and WD repeat domain containing 10
chr1_+_145525041 1.739 ITGA10
integrin, alpha 10
chr8_-_146202727 1.738 ZNF252
zinc finger protein 252
chr14_+_32546445 1.727 NM_001030055
NM_001173
 ARHGAP5

Rho GTPase activating protein 5

chr3_+_130569368 1.720 NM_001199180
NM_001199181
NM_001199182
 ATP2C1


ATPase, Ca++ transporting, type 2C, member 1


chr5_-_38595506 1.718 NM_002310
 LIFR
leukemia inhibitory factor receptor alpha
chr11_-_9225780 1.705 DENND5A
DENN/MADD domain containing 5A
chr10_+_24497719 1.704 NM_001098501
NM_019590
 KIAA1217

KIAA1217


Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
8.27 9.22e-05 GO:0030198 extracellular matrix organization
1.74 5.09e-04 GO:0016043 cellular component organization
1.70 8.70e-04 GO:0071840 cellular component organization or biogenesis
5.89 1.01e-03 GO:0043062 extracellular structure organization
2.59 1.45e-02 GO:0007155 cell adhesion
2.59 1.45e-02 GO:0022610 biological adhesion
1.81 1.49e-02 GO:0042221 response to chemical stimulus
2.37 4.31e-02 GO:0040011 locomotion
1.69 4.64e-02 GO:0071842 cellular component organization at cellular level

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
8.13 1.30e-06 GO:0044420 extracellular matrix part
10.10 9.09e-06 GO:0005604 basement membrane
3.92 3.97e-05 GO:0031012 extracellular matrix
4.16 6.85e-05 GO:0005578 proteinaceous extracellular matrix
2.34 1.19e-03 GO:0044421 extracellular region part
1.82 4.18e-03 GO:0005576 extracellular region
9.82 2.61e-02 GO:0005581 collagen

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
9.72 3.70e-06 GO:0005201 extracellular matrix structural constituent
5.34 6.42e-04 GO:0001871 pattern binding
5.34 6.42e-04 GO:0030247 polysaccharide binding
6.61 6.52e-04 GO:0019838 growth factor binding
2.83 1.78e-03 GO:0005198 structural molecule activity
14.14 5.33e-03 GO:0050840 extracellular matrix binding
5.73 6.54e-03 GO:0008201 heparin binding
4.81 1.08e-02 GO:0005539 glycosaminoglycan binding
3.10 1.54e-02 GO:0030246 carbohydrate binding
1.30 2.41e-02 GO:0005515 protein binding
5.24 3.46e-02 GO:0019955 cytokine binding
70.66 4.65e-02 GO:0004923 leukemia inhibitory factor receptor activity