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Motif ID: TBX4,5.p2

Z-value: 1.056

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr1_+_26737306	4.153		LIN28A	lin-28 homolog A (C. elegans)
chr11_+_61447816	3.135	NM_006133	DAGLA	diacylglycerol lipase, alpha
chr11_+_69061599	3.042	NM_138768	MYEOV	myeloma overexpressed (in a subset of t(11;14) positive multiple myelomas)
chr12_-_6756597	2.995		ACRBP	acrosin binding protein
chr11_-_124632050	2.979	NM_138961	ESAM	endothelial cell adhesion molecule
chr1_+_155911479	2.923	NM_181885	RXFP4	relaxin/insulin-like family peptide receptor 4
chr7_+_140103842	2.730	NM_001008749	RAB19	RAB19, member RAS oncogene family
chr19_+_50192440	2.714		C19orf76	chromosome 19 open reading frame 76
chr8_-_22550057	2.689	NM_001199881	EGR3	early growth response 3
chr12_-_45270071	2.678		NELL2	NEL-like 2 (chicken)
chr4_-_149363304	2.677		NR3C2	nuclear receptor subfamily 3, group C, member 2
chr20_+_58630965	2.663	NM_173644	C20orf197	chromosome 20 open reading frame 197
chr5_+_133842276	2.646
chr11_-_119234628	2.548		USP2	ubiquitin specific peptidase 2
chrY_+_15016698	2.461	NM_004660	DDX3Y	DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
chr12_+_52416615	2.398	NM_001202233	NR4A1	nuclear receptor subfamily 4, group A, member 1
chr9_-_34397786	2.360	NM_032596	C9orf24	chromosome 9 open reading frame 24
chr8_-_22549901	2.347	NM_001199880	EGR3	early growth response 3
chr22_-_33402648	2.315	NM_003490 NM_133633	SYN3	synapsin III
chr6_-_24936177	2.278		FAM65B	family with sequence similarity 65, member B
chr1_+_26737232	2.258	NM_024674	LIN28A	lin-28 homolog A (C. elegans)
chrX_-_130964633	2.180		LOC286467	family with sequence similarity 195, member A pseudogene
chr19_+_11998609	2.105	NM_021915	ZNF69	zinc finger protein 69
chr10_+_114135013	2.092	NM_203380	ACSL5	acyl-CoA synthetase long-chain family member 5
chr14_+_95078713	2.041	NM_001085	SERPINA3	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
chr15_-_31523049	2.014	NM_001243538	LOC283710	uncharacterized LOC283710
chr11_-_61062534	1.979		VWCE	von Willebrand factor C and EGF domains
chr22_+_50528307	1.979	NM_001164104 NM_018995	MOV10L1	Mov10l1, Moloney leukemia virus 10-like 1, homolog (mouse)
chr19_+_46733008	1.958	NM_198541	IGFL1	IGF-like family member 1
chr14_-_88737160	1.927	NM_138318	KCNK10	potassium channel, subfamily K, member 10
chrX_+_148793737	1.894	NM_005366	MAGEA11	melanoma antigen family A, 11
chr12_+_131438451	1.865	NM_198827	GPR133	G protein-coupled receptor 133
chr12_-_45270157	1.849	NM_001145108 NM_006159	NELL2	NEL-like 2 (chicken)
chr1_+_9005921	1.845	NM_001215	CA6	carbonic anhydrase VI
chr15_-_74501309	1.839	NM_001142617 NM_001142619 NM_001142620	STRA6	stimulated by retinoic acid gene 6 homolog (mouse)
chr1_+_11539177	1.835	NM_020780	PTCHD2	patched domain containing 2
chr1_-_11907741	1.829	NM_006172	NPPA	natriuretic peptide A
chr19_-_47137938	1.809	NM_033258	GNG8	guanine nucleotide binding protein (G protein), gamma 8
chr17_-_74533623	1.805	NM_134268	CYGB	cytoglobin
chr17_+_34431219	1.796	NM_002984	CCL4	chemokine (C-C motif) ligand 4
chr9_+_140032774	1.785		GRIN1	glutamate receptor, ionotropic, N-methyl D-aspartate 1
chr21_-_42880076	1.778		TMPRSS2	transmembrane protease, serine 2
chr17_+_4675175	1.770	NM_003963	TM4SF5	transmembrane 4 L six family member 5
chr19_+_7741934	1.766	NM_174918	C19orf59	chromosome 19 open reading frame 59
chr10_+_11060069	1.756		CELF2	CUGBP, Elav-like family member 2
chr22_+_24823529	1.753	NM_000675	ADORA2A	adenosine A2a receptor
chr8_-_142377364	1.739	NM_005293	GPR20	G protein-coupled receptor 20
chr17_+_28256873	1.734	NM_001145053	EFCAB5	EF-hand calcium binding domain 5
chr21_-_42880080	1.733	NM_005656	TMPRSS2	transmembrane protease, serine 2
chr13_+_31287614	1.710	NM_001204406	ALOX5AP	arachidonate 5-lipoxygenase-activating protein
chr5_+_132009372	1.709	NM_000589 NM_172348	IL4	interleukin 4
chr6_+_31543340	1.689	NM_000594	TNF	tumor necrosis factor
chr6_-_13295817	1.683	NM_001242698	LOC100130357	uncharacterized LOC100130357
chr9_-_104198045	1.679	NM_000035	ALDOB	aldolase B, fructose-bisphosphate
chrX_+_69642880	1.661	NM_001171191 NM_001171192 NM_001171193 NM_017711	GDPD2	glycerophosphodiester phosphodiesterase domain containing 2
chr16_-_88933015	1.647	NM_001080487	PABPN1L	poly(A) binding protein, nuclear 1-like (cytoplasmic)
chr6_+_32936375	1.637
chr4_-_149363498	1.631	NM_000901 NM_001166104	NR3C2	nuclear receptor subfamily 3, group C, member 2
chrY_+_15016018	1.622	NM_001122665	DDX3Y	DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
chr14_-_106967080	1.616		IGHG1	immunoglobulin heavy constant gamma 1 (G1m marker)
chr11_-_119252267	1.603		USP2	ubiquitin specific peptidase 2
chr12_-_95942570	1.592	NM_001042403	USP44	ubiquitin specific peptidase 44
chr3_+_137728949	1.586	NM_016369	CLDN18	claudin 18
chr2_+_113670547	1.584	NM_014439 NM_173202 NM_173203 NM_173204	IL37	interleukin 37
chr2_-_241759627	1.583	NM_001244008 NM_004321	KIF1A	kinesin family member 1A
chr22_-_30662787	1.567	NM_020530	OSM	oncostatin M
chr7_-_150675236	1.564	NM_000238 NM_172056	KCNH2	potassium voltage-gated channel, subfamily H (eag-related), member 2
chr3_+_134514300	1.557		EPHB1	EPH receptor B1
chrX_-_63450486	1.556	NM_130388	ASB12	ankyrin repeat and SOCS box containing 12
chr21_+_46031995	1.556	NM_198695	KRTAP10-8	keratin associated protein 10-8
chr16_+_88493878	1.554	NM_001127464	ZNF469	zinc finger protein 469
chr2_+_176972005	1.553	NM_021192	HOXD11	homeobox D11
chr21_-_42879908	1.537	NM_001135099	TMPRSS2	transmembrane protease, serine 2
chr11_-_61062697	1.536	NM_152718	VWCE	von Willebrand factor C and EGF domains
chr13_+_35516390	1.511	NM_015678	NBEA	neurobeachin
chr3_+_12045803	1.502	NM_003178 NM_133625	SYN2	synapsin II
chr14_-_107211131	1.497		IGHG1	immunoglobulin heavy constant gamma 1 (G1m marker)
chr8_+_24151579	1.493	NM_014265 NM_021777	ADAM28	ADAM metallopeptidase domain 28
chr1_+_38022514	1.486	NM_003462	DNALI1	dynein, axonemal, light intermediate chain 1
chr19_+_7828034	1.485	NM_001144904 NM_001144905 NM_001144906 NM_001144907 NM_001144908 NM_001144909 NM_001144910 NM_001144911 NM_014257	CLEC4M	C-type lectin domain family 4, member M
chr3_-_120400957	1.476		HGD	homogentisate 1,2-dioxygenase
chr16_+_1203240	1.476	NM_001005407 NM_021098	CACNA1H	calcium channel, voltage-dependent, T type, alpha 1H subunit
chrX_+_101906293	1.467	NM_001099410 NM_001099411 NM_014710 NM_001184727	GPRASP1	G protein-coupled receptor associated sorting protein 1
chr12_-_45269953	1.467		NELL2	NEL-like 2 (chicken)
chr11_+_131780537	1.462	NM_001144058 NM_001144059 NM_016522	NTM	neurotrimin
chr3_+_120627026	1.435	NM_014980	STXBP5L	syntaxin binding protein 5-like
chr2_+_29204163	1.434	NM_199280	FAM179A	family with sequence similarity 179, member A
chr14_+_105391154	1.431		PLD4	phospholipase D family, member 4
chr12_+_52445185	1.429	NM_002135 NM_173157	NR4A1	nuclear receptor subfamily 4, group A, member 1
chr9_+_102584136	1.429	NM_006981 NM_173199 NM_173200	NR4A3	nuclear receptor subfamily 4, group A, member 3
chr5_+_1225469	1.425	NM_182632	SLC6A18	solute carrier family 6, member 18
chr7_+_87257704	1.425	NM_001134405 NM_001134406 NM_138290	RUNDC3B	RUN domain containing 3B
chr2_-_175869910	1.425	NM_001822 NM_001025201	CHN1	chimerin (chimaerin) 1
chr12_-_6756533	1.421	NM_032489	ACRBP	acrosin binding protein
chr2_+_113672769	1.420	NM_173205	IL37	interleukin 37
chr10_+_72238529	1.419	NM_014431	KIAA1274	KIAA1274
chr12_-_91348950	1.417	NM_152638	C12orf12	chromosome 12 open reading frame 12
chrX_-_114468604	1.414	NM_001243963 NM_020871	LRCH2	leucine-rich repeats and calponin homology (CH) domain containing 2
chr6_-_28303910	1.400	NM_001135216 NM_001243243	ZNF323	zinc finger protein 323
chr10_-_46970483	1.399		SYT15	synaptotagmin XV
chr11_-_119252364	1.395	NM_001243759 NM_004205	USP2	ubiquitin specific peptidase 2
chr2_-_42720476	1.394		KCNG3	potassium voltage-gated channel, subfamily G, member 3
chr16_-_77468930	1.391	NM_199355	ADAMTS18	ADAM metallopeptidase with thrombospondin type 1 motif, 18
chr11_-_128737132	1.387	NM_153764 NM_153765 NM_153766 NM_153767	KCNJ1	potassium inwardly-rectifying channel, subfamily J, member 1
chr11_+_131781303	1.381		NTM	neurotrimin
chr11_+_6260321	1.370	NM_001037329	CNGA4	cyclic nucleotide gated channel alpha 4
chr15_+_74421986	1.366	NM_001130137	ISLR2	immunoglobulin superfamily containing leucine-rich repeat 2
chr3_+_134514044	1.365	NM_004441	EPHB1	EPH receptor B1
chr12_-_8025419	1.363	NM_153449	SLC2A14	solute carrier family 2 (facilitated glucose transporter), member 14
chr17_-_3461030	1.362		TRPV3	transient receptor potential cation channel, subfamily V, member 3
chr1_+_110693131	1.350	NM_001010898	SLC6A17	solute carrier family 6, member 17
chr8_-_143833924	1.347	NM_205545	LYPD2	LY6/PLAUR domain containing 2
chr19_+_50796820	1.343		MYH14	myosin, heavy chain 14, non-muscle
chr22_+_32750871	1.343	NM_006604	RFPL3	ret finger protein-like 3
chr11_-_118550354	1.337	NM_007180	TREH	trehalase (brush-border membrane glycoprotein)
chr15_-_90294359	1.327	NM_018670	MESP1	mesoderm posterior 1 homolog (mouse)
chr16_+_24267474	1.324		CACNG3	calcium channel, voltage-dependent, gamma subunit 3
chr3_+_132757170	1.321	NM_001136469 NM_023943	TMEM108	transmembrane protein 108
chr10_+_114135965	1.317		ACSL5	acyl-CoA synthetase long-chain family member 5
chr4_-_107957452	1.315	NM_014421	DKK2	dickkopf 2 homolog (Xenopus laevis)
chr11_-_2159472	1.306		IGF2	insulin-like growth factor 2 (somatomedin A)
chr11_-_64490654	1.305	NM_015080 NM_138732	NRXN2	neurexin 2
chr16_+_89696674	1.304		DPEP1	dipeptidase 1 (renal)
chr4_-_57547845	1.300	NM_001145460 NM_032495 NM_139212	HOPX	HOP homeobox
chr18_+_55102777	1.300	NM_004852	ONECUT2	one cut homeobox 2
chr19_-_57183122	1.293	NM_001005850	ZNF835	zinc finger protein 835
chr7_-_103629962	1.293	NM_005045 NM_173054	RELN	reelin
chr6_+_72596648	1.292	NM_014989	RIMS1	regulating synaptic membrane exocytosis 1
chr19_-_54327428	1.285	NM_144687	NLRP12	NLR family, pyrin domain containing 12
chr13_-_50699775	1.285		DLEU2	deleted in lymphocytic leukemia 2 (non-protein coding)
chr5_-_37835928	1.284	NM_001190468 NM_001190469	GDNF	glial cell derived neurotrophic factor
chr14_-_106453162	1.284		IGHG1	immunoglobulin heavy constant gamma 1 (G1m marker)
chr2_-_70314065	1.280		PCBP1-AS1	PCBP1 antisense RNA 1 (non-protein coding)
chr10_-_99531712	1.273	NM_003015	SFRP5	secreted frizzled-related protein 5
chr12_-_53097246	1.272	NM_175078	KRT77	keratin 77
chr8_+_99439249	1.272	NM_020697	KCNS2	potassium voltage-gated channel, delayed-rectifier, subfamily S, member 2
chr1_-_92949355	1.270	NM_001127215	GFI1	growth factor independent 1 transcription repressor
chr11_+_1861431	1.268	NM_001145841	TNNI2	troponin I type 2 (skeletal, fast)
chr5_-_157079087	1.267
chr10_-_72545110	1.266	NM_152710	C10orf27	chromosome 10 open reading frame 27
chrX_-_130423034	1.262	NM_001170963	IGSF1	immunoglobulin superfamily, member 1
chr12_+_119419299	1.259	NM_194286	SRRM4	serine/arginine repetitive matrix 4
chr7_+_86274076	1.259		GRM3	glutamate receptor, metabotropic 3
chr1_-_152595578	1.257	NM_178431	LCE3A	late cornified envelope 3A
chr1_+_185703470	1.256	NM_031935	HMCN1	hemicentin 1
chr12_+_66583029	1.253		IRAK3	interleukin-1 receptor-associated kinase 3
chr4_+_90816002	1.252	NM_007351	MMRN1	multimerin 1
chr11_-_117698727	1.249	NM_021603	FXYD2	FXYD domain containing ion transport regulator 2
chr9_+_115249078	1.247	NM_133465	KIAA1958	KIAA1958
chr11_+_26353677	1.246	NM_031418	ANO3	anoctamin 3
chrX_+_8432870	1.246	NM_001001888	VCX3B VCX3A	variable charge, X-linked 3B variable charge, X-linked 3A
chr19_+_15904760	1.243	NM_001004466	OR10H5	olfactory receptor, family 10, subfamily H, member 5
chr15_+_74421698	1.243	NM_001130136	ISLR2	immunoglobulin superfamily containing leucine-rich repeat 2
chr6_-_11232901	1.241	NM_006403 NM_182966	NEDD9	neural precursor cell expressed, developmentally down-regulated 9
chr3_+_119500930	1.238		NR1I2	nuclear receptor subfamily 1, group I, member 2
chr7_+_143013218	1.235	NM_000083	CLCN1	chloride channel 1, skeletal muscle
chr16_+_28889808	1.234	NM_004320 NM_173201	ATP2A1	ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
chrX_+_102470003	1.234	NM_001080425 NM_001127688	BEX4	brain expressed, X-linked 4
chr19_-_39108534	1.232	NM_001042600 NM_007181	MAP4K1	mitogen-activated protein kinase kinase kinase kinase 1
chr1_-_45308603	1.231	NM_001166292 NM_003738	PTCH2	patched 2
chr5_-_151784664	1.231	NM_020167	NMUR2	neuromedin U receptor 2
chr19_-_36247917	1.231	NM_144617	HSPB6	heat shock protein, alpha-crystallin-related, B6
chr19_-_35625989	1.225	NM_139284	LGI4	leucine-rich repeat LGI family, member 4
chr20_-_45179212	1.222	NM_080721	C20orf123	chromosome 20 open reading frame 123
chr3_+_126113781	1.220	NM_182628	CCDC37	coiled-coil domain containing 37
chr5_+_113698304	1.217		KCNN2	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
chr19_-_45033547	1.217	NM_001102597 NM_001102598 NM_001102599 NM_001102600	CEACAM20	carcinoembryonic antigen-related cell adhesion molecule 20
chr1_-_201915715	1.216	NM_012134	LMOD1	leiomodin 1 (smooth muscle)
chr12_-_45270632	1.213	NM_001145107	NELL2	NEL-like 2 (chicken)
chr19_-_8212367	1.213	NM_032447	FBN3	fibrillin 3
chr2_-_217559497	1.206		IGFBP5	insulin-like growth factor binding protein 5
chr2_+_121103670	1.206	NM_002193	INHBB	inhibin, beta B
chr22_-_37505602	1.204		TMPRSS6	transmembrane protease, serine 6
chr14_+_105391150	1.204		PLD4	phospholipase D family, member 4
chr1_+_176432306	1.197	NM_020318 NM_021936	PAPPA2	pappalysin 2
chrX_-_9001090	1.196	NM_205849	FAM9B	family with sequence similarity 9, member B
chr17_+_7342688	1.195	NM_004112	FGF11	fibroblast growth factor 11
chr1_-_241520384	1.194		RGS7	regulator of G-protein signaling 7
chr3_+_25469749	1.192	NM_016152	RARB	retinoic acid receptor, beta
chr17_-_31620005	1.189	NM_183377	ACCN1	amiloride-sensitive cation channel 1, neuronal
chr19_+_1753661	1.187	NM_001080488	ONECUT3	one cut homeobox 3
chr6_+_35182182	1.185	NM_152753	SCUBE3	signal peptide, CUB domain, EGF-like 3
chr2_+_233320832	1.184	NM_001631	ALPI	alkaline phosphatase, intestinal
chr1_-_241520467	1.183	NM_002924	RGS7	regulator of G-protein signaling 7
chrX_-_100446277	1.179		YWHAQP8	YWHAQ pseudogene 8
chr5_-_1445510	1.179	NM_001044	SLC6A3	solute carrier family 6 (neurotransmitter transporter, dopamine), member 3
chr16_-_50715116	1.174		SNX20	sorting nexin 20
chr12_+_48722762	1.173	NM_181788	H1FNT	H1 histone family, member N, testis-specific
chr10_+_114135937	1.173	NM_016234	ACSL5	acyl-CoA synthetase long-chain family member 5
chr11_-_2182408	1.165	NM_000207 NM_001185097 NM_001185098 NM_001042376	INS INS-IGF2	insulin INS-IGF2 readthrough
chr12_+_54943358	1.163		PDE1B	phosphodiesterase 1B, calmodulin-dependent
chr2_+_169921298	1.160	NM_005771	DHRS9	dehydrogenase/reductase (SDR family) member 9
chr1_-_202129731	1.158		PTPN7	protein tyrosine phosphatase, non-receptor type 7
chr16_-_50715240	1.157	NM_001144972 NM_153337 NM_182854	SNX20	sorting nexin 20
chr19_-_2308155	1.150	NM_001101391	LINGO3	leucine rich repeat and Ig domain containing 3
chr9_-_137809710	1.148	NM_002003	FCN1	ficolin (collagen/fibrinogen domain containing) 1
chrX_+_46940235	1.148		RGN	regucalcin (senescence marker protein-30)
chr3_+_25469833	1.146	NM_000965	RARB	retinoic acid receptor, beta
chr12_-_114843888	1.145	NM_181486	TBX5	T-box 5
chr4_+_75174189	1.143	NM_001013442	EPGN	epithelial mitogen homolog (mouse)

Gene overrepresentation in process category:

Enrichment	P-value	GO Accession	GO Term
3.27	1.19e-02	GO:0035637	multicellular organismal signaling
1.50	1.35e-02	GO:0032501	multicellular organismal process

Gene overrepresentation in compartment category:

Enrichment	P-value	GO Accession	GO Term
1.96	8.78e-04	GO:0005576	extracellular region
1.92	9.99e-04	GO:0044459	plasma membrane part
1.59	1.50e-03	GO:0005886	plasma membrane
1.56	2.57e-03	GO:0071944	cell periphery
4.30	8.68e-03	GO:0034702	ion channel complex
4.82	4.21e-02	GO:0034703	cation channel complex

Gene overrepresentation in function category:

Enrichment	P-value	GO Accession	GO Term
3.63	1.09e-03	GO:0005216	ion channel activity
3.57	1.34e-03	GO:0022838	substrate-specific channel activity
12.18	1.82e-03	GO:0003823	antigen binding
3.46	1.99e-03	GO:0015267	channel activity
3.46	2.06e-03	GO:0022803	passive transmembrane transporter activity
3.78	4.76e-03	GO:0022836	gated channel activity
2.53	1.31e-02	GO:0015075	ion transmembrane transporter activity
3.70	2.29e-02	GO:0005261	cation channel activity
2.73	2.48e-02	GO:0008324	cation transmembrane transporter activity
2.27	4.55e-02	GO:0022891	substrate-specific transmembrane transporter activity