Motif ID: TBP.p2

Z-value: 2.697


Transcription factors associated with TBP.p2:

Gene SymbolEntrez IDGene Name
TBP 6908 TATA box binding protein

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
TBPhg19_v1_chr6_+_170863420_170863508-0.047.6e-01Click!


Activity profile for motif TBP.p2.

activity profile for motif TBP.p2


Sorted Z-values histogram for motif TBP.p2

Sorted Z-values for motif TBP.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TBP.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr19_-_35981345 51.887 NM_001244847
NM_207392
KRTDAP

keratinocyte differentiation-associated protein

chr12_-_53074172 43.125 NM_006121
KRT1
keratin 1
chr17_-_39216343 21.960 NM_001165252
LOC730755
keratin associated protein 2-4-like
chr1_-_153363544 19.298 NM_002964
S100A8
S100 calcium binding protein A8
chr19_+_12902286 17.373


chr17_-_39203423 16.951 NM_001123387
KRTAP2-1
keratin associated protein 2-1
chr17_-_39222126 16.343 NM_033184
KRTAP2-4
keratin associated protein 2-4
chr14_+_75745480 15.715 NM_005252
FOS
FBJ murine osteosarcoma viral oncogene homolog
chr1_-_153067000 14.979 NM_001024209
SPRR2E
small proline-rich protein 2E
chr1_+_153330329 14.899 NM_002965
S100A9
S100 calcium binding protein A9
chr17_+_7758380 14.385 NM_203411
TMEM88
transmembrane protein 88
chr1_-_203155827 14.120 CHI3L1
chitinase 3-like 1 (cartilage glycoprotein-39)
chr13_+_53602829 14.070 NM_006418
OLFM4
olfactomedin 4
chr1_+_153003677 14.039 NM_003125
SPRR1B
small proline-rich protein 1B
chr19_+_12902295 12.643 NM_002229
JUNB
jun B proto-oncogene
chr1_-_156675237 12.212 NM_001878
NM_001199723
CRABP2

cellular retinoic acid binding protein 2

chr1_+_152730505 12.146 NM_001025231
KPRP
keratinocyte proline-rich protein
chr3_+_193853930 10.822 NM_005524
HES1
hairy and enhancer of split 1, (Drosophila)
chr1_+_152881022 10.614 NM_005547
IVL
involucrin
chr2_-_73520448 10.025 NM_001965
EGR4
early growth response 4
chr1_-_203155813 9.957 CHI3L1
chitinase 3-like 1 (cartilage glycoprotein-39)
chrX_+_84498993 9.939 NM_021998
ZNF711
zinc finger protein 711
chr12_+_55248298 9.745 NM_058173
MUCL1
mucin-like 1
chr8_-_82395401 9.697 NM_001442
FABP4
fatty acid binding protein 4, adipocyte
chr17_-_78450247 9.690 NM_002522
NPTX1
neuronal pentraxin I
chr1_-_153044083 9.674 NM_001017418
SPRR2B
small proline-rich protein 2B
chr17_-_39211462 9.651 NM_033032
KRTAP2-2
keratin associated protein 2-2
chr3_+_193853937 9.573 HES1
hairy and enhancer of split 1, (Drosophila)
chr1_-_153013593 9.426 NM_006945
SPRR2D
small proline-rich protein 2D
chr9_-_33447527 9.154 NM_004925
AQP3
aquaporin 3 (Gill blood group)
chr19_+_16435632 8.665 NM_016270
KLF2
Kruppel-like factor 2 (lung)
chr11_-_2950593 8.497 NM_003311
PHLDA2
pleckstrin homology-like domain, family A, member 2
chr6_+_26104103 8.197 NM_003542
HIST2H4B
HIST1H4C
histone cluster 2, H4b
histone cluster 1, H4c
chr1_-_203155867 8.059 CHI3L1
chitinase 3-like 1 (cartilage glycoprotein-39)
chr6_-_26216871 7.609 NM_003518
HIST1H2BG
NCALD
histone cluster 1, H2bg
neurocalcin delta
chr4_-_74964836 7.548 CXCL2
chemokine (C-X-C motif) ligand 2
chr1_-_152297678 7.503 NM_002016
FLG
filaggrin
chr8_-_24814028 7.459 NM_006158
NEFL
neurofilament, light polypeptide
chr1_-_153123426 7.412 NM_001014291
SPRR2G
small proline-rich protein 2G
chr1_-_153029987 7.352 NM_005988
SPRR2A
small proline-rich protein 2A
chr1_-_152131703 7.267 NM_001122965
RPTN
repetin
chr5_-_57755787 7.060 NM_001252226
NM_006622
PLK2

polo-like kinase 2

chr1_+_37940180 7.046 ZC3H12A
zinc finger CCCH-type containing 12A
chr11_-_102651321 7.034 NM_002425
MMP10
matrix metallopeptidase 10 (stromelysin 2)
chr8_-_143695812 6.949 NM_015193
ARC
activity-regulated cytoskeleton-associated protein
chr6_-_26189303 6.880 NM_003539
HIST1H4D
histone cluster 1, H4d
chr1_-_95007139 6.701 NM_001178096
NM_001993
F3

coagulation factor III (thromboplastin, tissue factor)

chr9_-_37034358 6.657 NM_016734
PAX5
paired box 5
chr5_+_53751430 6.629 NM_006308
HSPB3
heat shock 27kDa protein 3
chr3_-_99594915 6.538 NM_014890
FILIP1L
filamin A interacting protein 1-like
chr4_+_75310852 6.513 NM_001657
AREG
amphiregulin
chr6_+_27114860 6.306 NM_080596
HIST1H2AH
histone cluster 1, H2ah
chr16_+_71392615 6.294 NM_001740
NM_007088
CALB2

calbindin 2

chr19_+_13263890 6.273 IER2
immediate early response 2
chr5_-_54468833 6.256 NM_001145734
NM_001170402
NM_152623
CDC20B


cell division cycle 20 homolog B (S. cerevisiae)


chr1_-_149812733 6.233 NM_021059
NM_001005464
HIST2H3C
HIST2H3A
histone cluster 2, H3c
histone cluster 2, H3a
chr1_-_152539228 6.213 NM_178435
LCE3E
late cornified envelope 3E
chr1_+_17575592 6.118 NM_016233
PADI3
peptidyl arginine deiminase, type III
chr15_+_81071708 6.001 NM_018689
KIAA1199
KIAA1199
chr15_-_62457481 5.973 NM_001007595
C2CD4B
C2 calcium-dependent domain containing 4B
chr19_-_33793321 5.937


chr1_-_16482426 5.777 NM_004431
EPHA2
EPH receptor A2
chr16_+_71392637 5.696 CALB2
calbindin 2
chr19_-_51487070 5.676 NM_139277
NM_001207053
NM_001243126
NM_005046
KLK7



kallikrein-related peptidase 7



chr1_+_149824180 5.611 NM_021059
NM_001005464
HIST2H3C
HIST2H3A
histone cluster 2, H3c
histone cluster 2, H3a
chr15_+_62359175 5.608 NM_207322
C2CD4A
C2 calcium-dependent domain containing 4A
chr12_-_48119224 5.571 NM_001172439
NM_001172440
NM_006025
ENDOU


endonuclease, polyU-specific


chr6_-_27841287 5.467 NM_003546
HIST1H4L
histone cluster 1, H4l
chr11_-_102714240 5.456 NM_002422
MMP3
matrix metallopeptidase 3 (stromelysin 1, progelatinase)
chr13_-_53422773 5.438 NM_002590
NM_032949
PCDH8

protocadherin 8

chr1_+_12851545 5.427 NM_023013
PRAMEF1
PRAME family member 1
chr2_-_27531113 5.380 NM_003353
UCN
urocortin
chr5_-_147286064 5.374 NM_206966
C5orf46
chromosome 5 open reading frame 46
chr12_-_53045947 5.252 NM_000423
KRT2
keratin 2
chr2_-_151344145 5.249 NM_005168
RND3
Rho family GTPase 3
chr12_+_8975149 5.222 NM_144670
A2ML1
alpha-2-macroglobulin-like 1
chr11_-_94134575 5.186 NM_016540
GPR83
G protein-coupled receptor 83
chr19_-_36247917 5.138 NM_144617
HSPB6
heat shock protein, alpha-crystallin-related, B6
chr11_-_5248180 5.101 NM_000518
HBB
hemoglobin, beta
chr12_+_20963637 5.099 NM_019844
SLCO1B3
solute carrier organic anion transporter family, member 1B3
chr11_+_43963809 5.092 NM_001145033
C11orf96
chromosome 11 open reading frame 96
chr1_+_152658598 5.046 NM_014357
LCE2B
late cornified envelope 2B
chr16_+_56598960 4.990 NM_032935
MT4
metallothionein 4
chr21_+_19617145 4.989 NM_024944
CHODL
chondrolectin
chr1_-_203155745 4.946 CHI3L1
chitinase 3-like 1 (cartilage glycoprotein-39)
chr19_+_48958765 4.916 NM_013348
KCNJ14
potassium inwardly-rectifying channel, subfamily J, member 14
chr1_-_228613025 4.904 NM_003493
HIST3H3
histone cluster 3, H3
chr7_+_127881330 4.901 NM_000230
LEP
leptin
chr6_+_30951484 4.836 NM_001010909
MUC21
mucin 21, cell surface associated
chr12_-_11463353 4.774 NM_002723
PRB4
proline-rich protein BstNI subfamily 4
chr21_+_46057272 4.762 NM_181688
KRTAP10-10
keratin associated protein 10-10
chr12_+_52400725 4.757 NM_181711
GRASP
GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein
chr19_+_18496966 4.752 NM_004864
GDF15
growth differentiation factor 15
chrX_-_103499559 4.744 NM_153448
ESX1
ESX homeobox 1
chr17_-_38859976 4.712 NM_019016
KRT24
keratin 24
chr1_-_152386727 4.705 NM_016190
CRNN
cornulin
chr6_+_26156552 4.704 HIST1H1E
histone cluster 1, H1e
chr19_-_33793429 4.691 NM_004364
CEBPA
CCAAT/enhancer binding protein (C/EBP), alpha
chr17_-_39041436 4.677 NM_019010
KRT20
keratin 20
chr1_+_17634689 4.675 NM_012387
PADI4
peptidyl arginine deiminase, type IV
chr6_-_26250832 4.604 NM_021018
HIST1H3J
HIST1H3F
histone cluster 1, H3j
histone cluster 1, H3f
chr11_-_71955216 4.587 NM_005169
PHOX2A
paired-like homeobox 2a
chr21_+_26934440 4.569 MIR155HG
MIR155 host gene (non-protein coding)
chr11_-_76381787 4.555 NM_001128922
LRRC32
leucine rich repeat containing 32
chr14_+_93389491 4.552 CHGA
chromogranin A (parathyroid secretory protein 1)
chr6_-_26017960 4.516 NM_005325
HIST1H1A
histone cluster 1, H1a
chr19_+_35773409 4.516 NM_021175
HAMP
hepcidin antimicrobial peptide
chr19_+_14138959 4.505 NM_080864
RLN3
relaxin 3
chr15_-_63674074 4.505 NM_001218
NM_206925
CA12

carbonic anhydrase XII

chr17_-_79792867 4.493 PPP1R27
protein phosphatase 1, regulatory subunit 27
chr2_-_25391558 4.472 NM_000939
NM_001035256
POMC

proopiomelanocortin

chr19_+_840963 4.463 PRTN3
proteinase 3
chr14_+_31343642 4.397 NM_001135058
NM_004086
COCH

coagulation factor C homolog, cochlin (Limulus polyphemus)

chr10_-_100027943 4.372 NM_032211
LOXL4
lysyl oxidase-like 4
chr7_+_100770378 4.350 NM_000602
NM_001165413
SERPINE1

serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1

chr16_+_78056411 4.345 NM_005752
CLEC3A
C-type lectin domain family 3, member A
chr11_+_60635014 4.336 NM_207341
ZP1
zona pellucida glycoprotein 1 (sperm receptor)
chr3_-_169482847 4.328 TERC
telomerase RNA component
chr4_+_74606222 4.291 NM_000584
IL8
interleukin 8
chr6_-_2903461 4.277 NM_004155
SERPINB9
serpin peptidase inhibitor, clade B (ovalbumin), member 9
chr11_+_67183144 4.276 NM_001166222
NM_020811
CARNS1

carnosine synthase 1

chr21_-_31852631 4.250 NM_181607
KRTAP19-1
keratin associated protein 19-1
chr19_-_18902077 4.238 NM_000095
COMP
cartilage oligomeric matrix protein
chr2_+_85766100 4.225 NM_005911
MAT2A
methionine adenosyltransferase II, alpha
chr19_-_33793441 4.208 CEBPA
CCAAT/enhancer binding protein (C/EBP), alpha
chr11_+_68452007 4.126 GAL
galanin prepropeptide
chr12_-_53012332 4.123 NM_175068
KRT73
keratin 73
chr17_-_39890882 4.118 NM_001079870
NM_001079871
NM_177977
HAP1


huntingtin-associated protein 1


chr17_-_79792923 4.097 NM_001007533
PPP1R27
protein phosphatase 1, regulatory subunit 27
chr17_-_39768939 4.071 NM_005557
KRT16
keratin 16
chr17_-_39183453 4.036 NM_031957
KRTAP1-5
keratin associated protein 1-5
chr6_-_26043884 4.035 NM_021062
HIST1H2BB
histone cluster 1, H2bb
chr17_-_39675078 3.998 NM_002275
KRT15
keratin 15
chr5_+_131993864 3.994 NM_002188
IL13
interleukin 13
chr1_-_169703178 3.983 NM_000450
SELE
selectin E
chr15_-_63673918 3.981 CA12
carbonic anhydrase XII
chr1_+_152769226 3.971 NM_178352
LCE1D
late cornified envelope 1D
chr1_+_163038934 3.963 NM_001113381
RGS4
regulator of G-protein signaling 4
chr10_-_72201438 3.947 NM_018055
NODAL
nodal homolog (mouse)
chr5_+_176811431 3.945 NM_001167579
NM_003052
SLC34A1

solute carrier family 34 (sodium phosphate), member 1

chr19_-_39303739 3.861 NM_006149
LGALS4
lectin, galactoside-binding, soluble, 4
chr17_-_56358266 3.847 NM_000250
MPO
myeloperoxidase
chr1_+_159557615 3.835 NM_001639
APCS
amyloid P component, serum
chr10_-_3827418 3.815 NM_001160124
NM_001160125
NM_001300
KLF6


Kruppel-like factor 6


chr7_+_75931991 3.810 HSPB1
heat shock 27kDa protein 1
chr4_+_71296208 3.797 NM_001145006
MUC7
mucin 7, secreted
chr4_-_107957452 3.739 NM_014421
DKK2
dickkopf 2 homolog (Xenopus laevis)
chr1_-_152196668 3.732 NM_001009931
HRNR
hornerin
chr7_+_100612903 3.720 NM_001164462
MUC12
mucin 12, cell surface associated
chr10_-_95170 3.717 NM_177987
TUBB8
tubulin, beta 8 class VIII
chr3_+_70048882 3.717


chr1_-_152332481 3.698 NM_001014342
FLG2
filaggrin family member 2
chr1_+_16330730 3.690 NM_178840
C1orf64
chromosome 1 open reading frame 64
chr11_+_1074869 3.684 NM_002457
MUC2
mucin 2, oligomeric mucus/gel-forming
chr11_+_64937624 3.669 NM_001008778
SPDYC
speedy homolog C (Xenopus laevis)
chr9_+_117085302 3.667 NM_000607
ORM1
orosomucoid 1
chr16_+_25228282 3.660 NM_001169
AQP8
aquaporin 8
chr17_-_10325266 3.653 NM_002472
MYH8
myosin, heavy chain 8, skeletal muscle, perinatal
chr15_-_51630735 3.646 NM_000103
NM_031226
CYP19A1

cytochrome P450, family 19, subfamily A, polypeptide 1

chr10_-_69455926 3.625 NM_013266
CTNNA3
catenin (cadherin-associated protein), alpha 3
chr2_-_163008913 3.615 NM_002054
GCG
glucagon
chr17_-_39538635 3.580 NM_021013
KRT34
keratin 34
chr3_+_42727010 3.574 NM_152393
KBTBD5
kelch repeat and BTB (POZ) domain containing 5
chr8_-_133071626 3.574 NM_001080399
OC90
otoconin 90
chr1_-_68915631 3.571 NM_000329
RPE65
retinal pigment epithelium-specific protein 65kDa
chr10_+_118380451 3.545 NM_005396
PNLIPRP2
pancreatic lipase-related protein 2
chr1_-_230849863 3.531 AGT
angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
chr1_-_203155910 3.507 NM_001276
CHI3L1
chitinase 3-like 1 (cartilage glycoprotein-39)
chr2_-_43453724 3.494 ZFP36L2
zinc finger protein 36, C3H type-like 2
chr1_-_230849847 3.489 AGT
angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
chr11_+_30252562 3.487 NM_000510
NM_001018080
FSHB

follicle stimulating hormone, beta polypeptide

chr16_-_4292052 3.478 NM_001098814
SRL
sarcalumenin
chr11_+_1718424 3.467 NM_001012416
KRTAP5-6
keratin associated protein 5-6
chr19_-_49926598 3.450 NM_178449
PTH2
parathyroid hormone 2
chr2_-_43453146 3.440 ZFP36L2
zinc finger protein 36, C3H type-like 2
chr17_+_32582295 3.437 NM_002982
CCL2
chemokine (C-C motif) ligand 2
chr1_-_11907741 3.422 NM_006172
NPPA
natriuretic peptide A
chr3_-_24536452 3.401 THRB
thyroid hormone receptor, beta
chr10_+_94833646 3.401 NM_000783
CYP26A1
cytochrome P450, family 26, subfamily A, polypeptide 1
chr16_+_72097124 3.398 NM_020995
HPR
haptoglobin-related protein
chr1_+_37940129 3.396 ZC3H12A
zinc finger CCCH-type containing 12A
chr18_-_44556448 3.396 NM_145653
TCEB3C
transcription elongation factor B polypeptide 3C (elongin A3)
chr15_+_75041182 3.381 NM_000761
CYP1A2
cytochrome P450, family 1, subfamily A, polypeptide 2
chr7_+_75931829 3.364 NM_001540
HSPB1
heat shock 27kDa protein 1
chr6_-_26108320 3.352 NM_005323
HIST1H1T
histone cluster 1, H1t
chr19_+_840970 3.352 NM_002777
PRTN3
proteinase 3
chr4_+_25657434 3.299 NM_001177998
NM_006424
SLC34A2

solute carrier family 34 (sodium phosphate), member 2

chr12_+_50344523 3.275 NM_000486
AQP2
aquaporin 2 (collecting duct)
chr11_-_1036654 3.275 NM_005961
MUC6
mucin 6, oligomeric mucus/gel-forming
chr7_+_30951414 3.249 NM_198098
AQP1
aquaporin 1 (Colton blood group)
chr1_-_20306093 3.237 NM_001161729
PLA2G2A
phospholipase A2, group IIA (platelets, synovial fluid)
chr11_-_102496049 3.212 NM_004771
MMP20
matrix metallopeptidase 20
chr2_+_85766286 3.212 MAT2A
methionine adenosyltransferase II, alpha
chr9_+_138555167 3.202 NM_001001676
LCN9
lipocalin 9
chr12_+_41086189 3.188 NM_001843
NM_175038
CNTN1

contactin 1

chr17_+_7554239 3.187 NM_001678
ATP1B2
ATPase, Na+/K+ transporting, beta 2 polypeptide
chr15_+_39873276 3.187 NM_003246
THBS1
thrombospondin 1
chr13_+_33590477 3.177 NM_004795
KL
klotho
chr18_+_52258389 3.162 NM_173629
C18orf26
chromosome 18 open reading frame 26
chr17_-_10560625 3.145 NM_002470
MYH3
myosin, heavy chain 3, skeletal muscle, embryonic

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
16.93 2.85e-13 GO:0031424 keratinization
5.35 5.84e-12 GO:0006954 inflammatory response
2.31 7.21e-12 GO:0048513 organ development
2.12 4.88e-11 GO:0042221 response to chemical stimulus
1.60 9.06e-11 GO:0032501 multicellular organismal process
6.08 1.14e-10 GO:0008544 epidermis development
11.11 5.40e-10 GO:0030216 keratinocyte differentiation
9.61 6.10e-09 GO:0009913 epidermal cell differentiation
7.84 1.06e-08 GO:0034728 nucleosome organization
2.79 1.45e-08 GO:0009611 response to wounding
8.21 1.90e-08 GO:0006334 nucleosome assembly
7.79 4.62e-08 GO:0031497 chromatin assembly
2.83 6.22e-08 GO:0006952 defense response
1.76 7.06e-08 GO:0048856 anatomical structure development
4.65 1.43e-07 GO:0009617 response to bacterium
2.63 1.90e-07 GO:0070887 cellular response to chemical stimulus
7.13 2.00e-07 GO:0065004 protein-DNA complex assembly
1.78 3.57e-07 GO:0048731 system development
1.64 4.13e-07 GO:0032502 developmental process
3.64 4.22e-07 GO:0051707 response to other organism
6.75 4.88e-07 GO:0071824 protein-DNA complex subunit organization
1.86 5.36e-07 GO:0006950 response to stress
2.63 1.07e-06 GO:0009888 tissue development
1.65 1.71e-06 GO:0007275 multicellular organismal development
2.98 2.21e-06 GO:0009725 response to hormone stimulus
5.64 2.97e-06 GO:0002237 response to molecule of bacterial origin
3.18 3.38e-06 GO:0009607 response to biotic stimulus
5.95 3.59e-06 GO:0006323 DNA packaging
2.22 4.78e-06 GO:0010033 response to organic substance
2.78 8.21e-06 GO:0009719 response to endogenous stimulus
5.60 9.28e-06 GO:0006333 chromatin assembly or disassembly
6.41 1.12e-05 GO:0008217 regulation of blood pressure
2.47 1.15e-05 GO:0051704 multi-organism process
4.83 1.44e-05 GO:0030855 epithelial cell differentiation
3.95 1.96e-05 GO:0010035 response to inorganic substance
5.51 3.25e-05 GO:0032496 response to lipopolysaccharide
5.11 3.77e-05 GO:0071103 DNA conformation change
3.84 6.85e-05 GO:0048545 response to steroid hormone stimulus
12.70 1.52e-04 GO:0070301 cellular response to hydrogen peroxide
2.24 2.06e-04 GO:0009605 response to external stimulus
6.08 2.14e-04 GO:0045765 regulation of angiogenesis
8.23 3.31e-04 GO:0002526 acute inflammatory response
9.53 3.60e-04 GO:0034614 cellular response to reactive oxygen species
27.78 3.83e-04 GO:0042738 exogenous drug catabolic process
1.34 4.85e-04 GO:0050896 response to stimulus
3.88 4.91e-04 GO:0032101 regulation of response to external stimulus
3.08 1.04e-03 GO:0060429 epithelium development
15.69 1.57e-03 GO:0045104 intermediate filament cytoskeleton organization
2.24 1.66e-03 GO:0040011 locomotion
22.22 1.66e-03 GO:0042737 drug catabolic process
5.56 1.76e-03 GO:0009266 response to temperature stimulus
5.03 2.03e-03 GO:0051384 response to glucocorticoid stimulus
8.67 3.64e-03 GO:0006721 terpenoid metabolic process
1.92 3.94e-03 GO:0051239 regulation of multicellular organismal process
13.33 4.65e-03 GO:0045103 intermediate filament-based process
4.66 4.77e-03 GO:0031960 response to corticosteroid stimulus
18.52 5.04e-03 GO:0032098 regulation of appetite
3.80 5.34e-03 GO:0010817 regulation of hormone levels
3.78 5.72e-03 GO:0003013 circulatory system process
3.78 5.72e-03 GO:0008015 blood circulation
6.67 8.45e-03 GO:0034599 cellular response to oxidative stress
12.12 8.62e-03 GO:0034367 macromolecular complex remodeling
12.12 8.62e-03 GO:0034368 protein-lipid complex remodeling
12.12 8.62e-03 GO:0034369 plasma lipoprotein particle remodeling
3.45 9.92e-03 GO:0008202 steroid metabolic process
6.45 1.12e-02 GO:0009408 response to heat
8.89 1.32e-02 GO:0003014 renal system process
11.11 1.50e-02 GO:0042743 hydrogen peroxide metabolic process
2.12 1.51e-02 GO:0043933 macromolecular complex subunit organization
2.06 1.56e-02 GO:0050793 regulation of developmental process
6.16 1.66e-02 GO:0019748 secondary metabolic process
6.06 1.88e-02 GO:0007631 feeding behavior
5.29 2.14e-02 GO:0001890 placenta development
4.04 2.29e-02 GO:0042445 hormone metabolic process
2.31 2.34e-02 GO:0048878 chemical homeostasis
5.23 2.37e-02 GO:0050795 regulation of behavior
10.26 2.47e-02 GO:0071825 protein-lipid complex subunit organization
10.26 2.47e-02 GO:0071827 plasma lipoprotein particle organization
13.89 2.59e-02 GO:0003091 renal water homeostasis
13.89 2.59e-02 GO:0050891 multicellular organismal water homeostasis
2.77 2.59e-02 GO:0034622 cellular macromolecular complex assembly
2.48 2.86e-02 GO:0034621 cellular macromolecular complex subunit organization
6.59 3.09e-02 GO:0051591 response to cAMP
7.78 3.34e-02 GO:0072593 reactive oxygen species metabolic process
5.00 3.57e-02 GO:0000302 response to reactive oxygen species
1.59 3.63e-02 GO:0065008 regulation of biological quality
19.75 3.86e-02 GO:0008343 adult feeding behavior
19.75 3.86e-02 GO:0045109 intermediate filament organization
12.35 4.89e-02 GO:0030104 water homeostasis
12.35 4.89e-02 GO:0042744 hydrogen peroxide catabolic process

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
2.82 1.04e-26 GO:0005576 extracellular region
4.12 9.70e-23 GO:0005615 extracellular space
3.58 3.88e-22 GO:0044421 extracellular region part
7.37 9.37e-15 GO:0005882 intermediate filament
6.38 4.29e-13 GO:0045111 intermediate filament cytoskeleton
12.59 1.23e-12 GO:0000786 nucleosome
7.95 4.07e-09 GO:0032993 protein-DNA complex
19.05 4.44e-08 GO:0001533 cornified envelope
7.59 4.66e-07 GO:0045095 keratin filament
17.28 1.08e-05 GO:0032982 myosin filament
6.95 2.15e-04 GO:0016459 myosin complex
1.83 3.04e-04 GO:0005856 cytoskeleton
3.48 5.92e-04 GO:0000785 chromatin
1.96 1.29e-03 GO:0044430 cytoskeletal part
14.82 1.80e-02 GO:0005833 hemoglobin complex
1.44 2.36e-02 GO:0043228 non-membrane-bounded organelle
1.44 2.36e-02 GO:0043232 intracellular non-membrane-bounded organelle
3.11 2.45e-02 GO:0030141 stored secretory granule
2.46 2.60e-02 GO:0031012 extracellular matrix
3.83 4.25e-02 GO:0030016 myofibril

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
8.53 1.05e-10 GO:0005179 hormone activity
3.17 7.39e-09 GO:0005198 structural molecule activity
6.14 4.05e-07 GO:0020037 heme binding
5.77 1.09e-06 GO:0046906 tetrapyrrole binding
9.88 9.78e-06 GO:0019825 oxygen binding
2.24 1.52e-05 GO:0005102 receptor binding
4.08 4.07e-05 GO:0005506 iron ion binding
4.39 6.44e-05 GO:0001664 G-protein-coupled receptor binding
4.13 7.39e-05 GO:0005125 cytokine activity
8.70 1.53e-04 GO:0008009 chemokine activity
7.84 3.85e-04 GO:0042379 chemokine receptor binding
2.92 4.76e-04 GO:0030246 carbohydrate binding
5.56 2.56e-03 GO:0004497 monooxygenase activity
22.22 4.07e-03 GO:0015250 water channel activity
13.89 4.82e-03 GO:0008395 steroid hydroxylase activity
19.75 7.19e-03 GO:0005372 water transmembrane transporter activity
33.33 1.13e-02 GO:0015168 glycerol transmembrane transporter activity
3.46 1.18e-02 GO:0005126 cytokine receptor binding
3.64 1.31e-02 GO:0001871 pattern binding
3.64 1.31e-02 GO:0030247 polysaccharide binding
3.63 2.60e-02 GO:0005539 glycosaminoglycan binding
13.68 3.81e-02 GO:0005344 oxygen transporter activity
4.01 4.41e-02 GO:0008201 heparin binding