Motif ID: T.p2

Z-value: 0.830


Transcription factors associated with T.p2:

Gene SymbolEntrez IDGene Name
T 6862 T, brachyury homolog (mouse)



Activity profile for motif T.p2.

activity profile for motif T.p2


Sorted Z-values histogram for motif T.p2

Sorted Z-values for motif T.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of T.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_+_69061599 11.847 NM_138768
MYEOV
myeloma overexpressed (in a subset of t(11;14) positive multiple myelomas)
chr12_-_53074172 10.845 NM_006121
KRT1
keratin 1
chr20_+_43343523 4.714 WISP2
WNT1 inducible signaling pathway protein 2
chr16_-_67965754 4.493 NM_001907
CTRL
chymotrypsin-like
chrX_+_152770083 3.449 BGN
biglycan
chr11_+_61447816 3.364 NM_006133
DAGLA
diacylglycerol lipase, alpha
chr14_+_95078713 3.333 NM_001085
SERPINA3
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
chrX_-_19688991 3.008 NM_001184960
SH3KBP1
SH3-domain kinase binding protein 1
chr1_-_200992510 2.852 KIF21B
kinesin family member 21B
chr17_+_25958217 2.534 LGALS9
lectin, galactoside-binding, soluble, 9
chr2_-_219031646 2.502 NM_000634
CXCR1
chemokine (C-X-C motif) receptor 1
chr17_+_25799024 2.301 NM_014238
KSR1
kinase suppressor of ras 1
chr17_+_25958245 2.193 LGALS9
lectin, galactoside-binding, soluble, 9
chr7_-_28220342 2.086 NM_175061
JAZF1
JAZF zinc finger 1
chr10_+_90562486 2.069 NM_001128215
LIPM
lipase, family member M
chr17_+_25958192 2.053 LGALS9
lectin, galactoside-binding, soluble, 9
chr17_+_25958151 2.033 NM_002308
NM_009587
LGALS9

lectin, galactoside-binding, soluble, 9

chr19_-_38188344 1.992 ZNF607
zinc finger protein 607
chr19_-_56704420 1.909 NM_001080456
ZSCAN5B
zinc finger and SCAN domain containing 5B
chr8_+_75736771 1.847 NM_015886
PI15
peptidase inhibitor 15
chr17_+_25958257 1.765 LGALS9
lectin, galactoside-binding, soluble, 9
chr2_+_176972005 1.704 NM_021192
HOXD11
homeobox D11
chrX_-_106146546 1.692 NM_001171706
NM_138382
RIPPLY1

ripply1 homolog (zebrafish)

chr20_+_43343884 1.688 NM_003881
WISP2
WNT1 inducible signaling pathway protein 2
chr19_-_44831907 1.615 ZFP112
zinc finger protein 112 homolog (mouse)
chr19_+_54965628 1.558


chr16_-_4323055 1.549 TFAP4
transcription factor AP-4 (activating enhancer binding protein 4)
chr11_-_66112537 1.413 NM_001024957
NM_015399
BRMS1

breast cancer metastasis suppressor 1

chr12_-_52867521 1.393 NM_173086
KRT6C
keratin 6C
chr1_-_1009686 1.375 NM_001205252
RNF223
ring finger protein 223
chr5_+_32173481 1.366 LOC153546
uncharacterized LOC153546
chr10_-_16564003 1.294 NM_001010908
C1QL3
complement component 1, q subcomponent-like 3
chr6_+_167536240 1.291 NM_031409
CCR6
chemokine (C-C motif) receptor 6
chr2_+_171571800 1.287 NM_001003845
SP5
Sp5 transcription factor
chr1_+_228395740 1.285 NM_001098623
NM_052843
OBSCN

obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF

chr5_+_31799030 1.272 NM_178140
PDZD2
PDZ domain containing 2
chr2_-_100722328 1.262 AFF3
AF4/FMR2 family, member 3
chr12_+_113623364 1.207 NM_032848
C12orf52
chromosome 12 open reading frame 52
chr17_+_79609298 1.192 NM_031945
TSPAN10
tetraspanin 10
chr2_+_171571936 1.119


chr3_+_137728949 1.107 NM_016369
CLDN18
claudin 18
chr16_+_77233348 1.103 NM_001129979
SYCE1L
synaptonemal complex central element protein 1-like
chr22_-_38479148 1.097 NM_013356
SLC16A8
solute carrier family 16, member 8 (monocarboxylic acid transporter 3)
chrX_+_16804531 1.094 NM_001168683
NM_018360
TXLNG

taxilin gamma

chr19_-_14260728 1.085 LPHN1
latrophilin 1
chr17_-_61523544 1.053 NM_001017916
NM_001915
CYB561

cytochrome b-561

chr3_+_47029453 1.050 NBEAL2
neurobeachin-like 2
chrM_+_8857 1.043


chrX_+_37639306 1.034 CYBB
cytochrome b-245, beta polypeptide
chr22_-_41215251 1.012 NM_006358
SLC25A17
solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17
chr19_+_55591759 0.970 NM_017729
EPS8L1
EPS8-like 1
chr1_+_26737232 0.962 NM_024674
LIN28A
lin-28 homolog A (C. elegans)
chr1_+_26737306 0.947 LIN28A
lin-28 homolog A (C. elegans)
chr2_+_171572698 0.935 SP5
Sp5 transcription factor
chr16_+_69220940 0.915 NM_006750
SNTB2
syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
chr19_-_55767103 0.910 PPP6R1
protein phosphatase 6, regulatory subunit 1
chr7_+_30791744 0.906 NM_001199219
NM_006774
INMT-FAM188B
INMT

INMT-FAM188B readthrough (non-protein coding)
indolethylamine N-methyltransferase

chr17_-_40307015 0.869 NM_001252039
NM_004583
NM_201434
RAB5C


RAB5C, member RAS oncogene family


chr10_+_70847857 0.862 SRGN
serglycin
chr14_-_107211131 0.855 IGHG1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr2_+_233320832 0.855 NM_001631
ALPI
alkaline phosphatase, intestinal
chr11_-_2170792 0.839 NM_001007139
IGF2
insulin-like growth factor 2 (somatomedin A)
chr20_+_35973083 0.830 NM_005417
SRC
v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
chr10_+_70847817 0.825 NM_002727
SRGN
serglycin
chr12_-_8043743 0.822 SLC2A14
solute carrier family 2 (facilitated glucose transporter), member 14
chr9_+_139872014 0.813 PTGDS
prostaglandin D2 synthase 21kDa (brain)
chrX_+_91089658 0.807 NM_014522
NM_032968
NM_032969
PCDH11X


protocadherin 11 X-linked


chr12_-_52845862 0.806 NM_005555
KRT6B
keratin 6B
chrX_+_70443055 0.802 NM_000166
GJB1
gap junction protein, beta 1, 32kDa
chrM_+_9217 0.796


chr17_-_40306935 0.791 RAB5C
RAB5C, member RAS oncogene family
chr1_+_28585959 0.783 NM_031459
SESN2
sestrin 2
chr7_+_143013218 0.774 NM_000083
CLCN1
chloride channel 1, skeletal muscle
chr3_-_93747453 0.772 NM_001001850
STX19
syntaxin 19
chr16_-_4323000 0.771 NM_003223
TFAP4
transcription factor AP-4 (activating enhancer binding protein 4)
chr11_-_93583667 0.767 NM_001144871
VSTM5
V-set and transmembrane domain containing 5
chr1_-_204135420 0.762 NM_000537
REN
renin
chrM_+_8364 0.756


chrX_+_69642880 0.747 NM_001171191
NM_001171192
NM_001171193
NM_017711
GDPD2



glycerophosphodiester phosphodiesterase domain containing 2



chr14_-_107113943 0.740 IGHA1
IGHG1
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr1_-_20306093 0.736 NM_001161729
PLA2G2A
phospholipase A2, group IIA (platelets, synovial fluid)
chr1_+_17531619 0.734 NM_013358
PADI1
peptidyl arginine deiminase, type I
chrM_+_9182 0.716


chrX_+_70443459 0.686 GJB1
gap junction protein, beta 1, 32kDa
chr17_-_40306988 0.680 RAB5C
RAB5C, member RAS oncogene family
chr11_-_3692544 0.653 NM_020402
CHRNA10
cholinergic receptor, nicotinic, alpha 10
chr3_+_133502876 0.652 NM_021203
SRPRB
signal recognition particle receptor, B subunit
chr12_-_51663969 0.652 NM_001033873
NM_001031628
SMAGP

small cell adhesion glycoprotein

chr21_-_47704166 0.639 MCM3AP
minichromosome maintenance complex component 3 associated protein
chr19_-_17958773 0.637 JAK3
Janus kinase 3
chr11_-_7847518 0.624 NM_153445
OR5P3
olfactory receptor, family 5, subfamily P, member 3
chr17_-_43502992 0.612 NM_199282
ARHGAP27
Rho GTPase activating protein 27
chr11_-_124806302 0.611 NM_152722
HEPACAM
hepatic and glial cell adhesion molecule
chr14_-_24809031 0.608 NM_006871
RIPK3
receptor-interacting serine-threonine kinase 3
chr11_-_7818488 0.607 NM_153444
OR5P2
olfactory receptor, family 5, subfamily P, member 2
chr5_+_175665337 0.602 NM_198567
C5orf25
chromosome 5 open reading frame 25
chrY_+_4924128 0.584 NM_032972
NM_032973
PCDH11X
PCDH11Y

protocadherin 11 X-linked
protocadherin 11 Y-linked

chr9_-_75567915 0.582 ALDH1A1
aldehyde dehydrogenase 1 family, member A1
chr7_-_16505292 0.580 NM_015464
SOSTDC1
sclerostin domain containing 1
chr15_+_91447419 0.576 NM_006122
MAN2A2
mannosidase, alpha, class 2A, member 2
chr5_-_14011846 0.574 DNAH5
dynein, axonemal, heavy chain 5
chr9_-_75568232 0.570 NM_000689
ALDH1A1
aldehyde dehydrogenase 1 family, member A1
chr15_-_90294359 0.568 NM_018670
MESP1
mesoderm posterior 1 homolog (mouse)
chr20_-_43743723 0.566 NM_145652
WFDC5
WAP four-disulfide core domain 5
chrX_-_62648209 0.565 LOC92249
uncharacterized LOC92249
chr6_-_109762373 0.562 NM_001111298
NM_173672
PPIL6

peptidylprolyl isomerase (cyclophilin)-like 6

chr10_+_5136589 0.558 AKR1C3
aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
chr1_-_154842725 0.545 NM_001204087
NM_002249
KCNN3

potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3

chr3_-_15140648 0.542 ZFYVE20
zinc finger, FYVE domain containing 20
chr3_-_100712248 0.541 NM_015429
ABI3BP
ABI family, member 3 (NESH) binding protein
chr15_+_60296506 0.540 FOXB1
forkhead box B1
chr4_-_149363498 0.529 NM_000901
NM_001166104
NR3C2

nuclear receptor subfamily 3, group C, member 2

chr15_+_60296420 0.527 NM_012182
FOXB1
forkhead box B1
chr15_-_83474805 0.525 NM_001007122
FSD2
fibronectin type III and SPRY domain containing 2
chr4_+_8582216 0.524 NM_080819
GPR78
G protein-coupled receptor 78
chr15_+_40861509 0.515 RPUSD2
RNA pseudouridylate synthase domain containing 2
chr1_+_33219544 0.515


chr6_+_109762204 0.510 SMPD2
sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
chr16_+_25228282 0.504 NM_001169
AQP8
aquaporin 8
chr2_+_103089761 0.504 NM_001011552
SLC9A4
solute carrier family 9 (sodium/hydrogen exchanger), member 4
chr11_+_122709205 0.489 NM_019604
CRTAM
cytotoxic and regulatory T cell molecule
chr5_+_36608430 0.478 NM_001166695
SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr14_-_21572789 0.473 NM_001102454
ZNF219
zinc finger protein 219
chr10_+_96443250 0.466 NM_000772
NM_001128925
CYP2C18

cytochrome P450, family 2, subfamily C, polypeptide 18

chr10_-_101690655 0.447 DNMBP
dynamin binding protein
chr8_-_130799133 0.444 NM_031415
GSDMC
gasdermin C
chr12_-_54541008 0.442


chr10_-_98945379 0.440 SLIT1
slit homolog 1 (Drosophila)
chr2_-_200322699 0.439 NM_001172509
SATB2
SATB homeobox 2
chr3_+_25470067 0.438 RARB
retinoic acid receptor, beta
chr13_-_20346398 0.435 PSPC1
paraspeckle component 1
chr18_-_56296188 0.435 NM_052947
ALPK2
alpha-kinase 2
chr12_-_53097246 0.433 NM_175078
KRT77
keratin 77
chr22_+_22676814 0.430


chr19_-_54311958 0.427 NM_033297
NLRP12
NLR family, pyrin domain containing 12
chr17_-_39211462 0.425 NM_033032
KRTAP2-2
keratin associated protein 2-2
chr9_-_37034358 0.422 NM_016734
PAX5
paired box 5
chr1_+_66797775 0.419 NM_001037339
PDE4B
phosphodiesterase 4B, cAMP-specific
chr11_+_129685732 0.418 NM_138788
TMEM45B
transmembrane protein 45B
chr4_-_149363304 0.416 NR3C2
nuclear receptor subfamily 3, group C, member 2
chr10_-_61122219 0.413 NM_001001971
NM_001166698
NM_198215
FAM13C


family with sequence similarity 13, member C


chrX_+_128913897 0.410 SASH3
SAM and SH3 domain containing 3
chr6_+_36922208 0.404 NM_153370
PI16
peptidase inhibitor 16
chr21_+_25801042 0.404 FLJ42200
FLJ42200 protein
chr17_+_34431219 0.402 NM_002984
CCL4
chemokine (C-C motif) ligand 4
chr3_+_25469749 0.402 NM_016152
RARB
retinoic acid receptor, beta
chr7_-_50628744 0.402 NM_000790
NM_001242886
NM_001242887
NM_001242888
NM_001242889
NM_001242890
DDC





dopa decarboxylase (aromatic L-amino acid decarboxylase)





chr11_-_111249902 0.398 POU2AF1
POU class 2 associating factor 1
chr7_-_5570188 0.396 NM_001101
ACTB
actin, beta
chr12_+_124773709 0.395 NM_181709
FAM101A
family with sequence similarity 101, member A
chr5_-_132112887 0.395 NM_001098811
NM_001098812
NM_015146
SEPT8


septin 8


chr9_+_135937364 0.391 NM_001807
CEL
carboxyl ester lipase (bile salt-stimulated lipase)
chr1_-_76076762 0.385 NM_001130058
NM_152697
SLC44A5

solute carrier family 44, member 5

chr1_-_153067000 0.380 NM_001024209
SPRR2E
small proline-rich protein 2E
chr10_+_5136556 0.378 NM_003739
AKR1C3
aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
chr7_-_81399286 0.368 NM_000601
NM_001010931
NM_001010932
NM_001010933
NM_001010934
HGF




hepatocyte growth factor (hepapoietin A; scatter factor)




chr8_-_42234562 0.366 NM_014420
DKK4
dickkopf homolog 4 (Xenopus laevis)
chr3_-_15140652 0.365 NM_022340
ZFYVE20
zinc finger, FYVE domain containing 20
chr14_-_107013474 0.365 IGHA1
IGHG1
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr4_+_155484131 0.364 NM_001184741
NM_005141
FGB

fibrinogen beta chain

chr4_-_145061787 0.360 NM_002099
GYPA
glycophorin A (MNS blood group)
chr7_-_752742 0.355 NM_001164761
PRKAR1B
protein kinase, cAMP-dependent, regulatory, type I, beta
chr7_+_72396799 0.354 POM121
POM121 membrane glycoprotein
chr5_+_1225469 0.354 NM_182632
SLC6A18
solute carrier family 6, member 18
chr1_-_41625539 0.353 NM_001172222
SCMH1
sex comb on midleg homolog 1 (Drosophila)
chr5_+_137419580 0.353 NM_058244
WNT8A
wingless-type MMTV integration site family, member 8A
chr9_-_73736513 0.335 NM_001007471
TRPM3
transient receptor potential cation channel, subfamily M, member 3
chr1_+_1846265 0.335 NM_138705
CALML6
calmodulin-like 6
chr2_+_228678556 0.335 NM_001130046
NM_004591
CCL20

chemokine (C-C motif) ligand 20

chr3_-_119582422 0.334 GSK3B
glycogen synthase kinase 3 beta
chr1_-_248738057 0.332 NM_001001821
OR2T34
olfactory receptor, family 2, subfamily T, member 34
chr6_-_49754899 0.332 NM_138733
PGK2
phosphoglycerate kinase 2
chr4_+_128651518 0.330 NM_031291
SLC25A31
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 31
chr17_+_75084724 0.328 NM_001204408
SEC14L1
LINC00338
SEC14-like 1 (S. cerevisiae)
long intergenic non-protein coding RNA 338
chr5_+_14664764 0.327 NM_138348
FAM105B
family with sequence similarity 105, member B
chr5_+_113698304 0.327 KCNN2
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
chr1_+_147013181 0.326 NM_004326
BCL9
B-cell CLL/lymphoma 9
chr10_+_5136613 0.325 AKR1C3
aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
chr5_-_177099174 0.325 LOC202181
chromosome 5 open reading frame 25 pseudogene
chr15_-_40630272 0.324 C15orf52
chromosome 15 open reading frame 52
chr21_-_34185943 0.323 NM_001162495
NM_001162496
NM_019596
C21orf62


chromosome 21 open reading frame 62


chr2_+_1418179 0.321 NM_175721
NM_175722
TPO

thyroid peroxidase

chr11_-_66103874 0.321 NM_004292
RIN1
Ras and Rab interactor 1
chr3_-_52443893 0.320 NM_004656
BAP1
BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
chr11_-_62689011 0.320 NM_000738
CHRM1
cholinergic receptor, muscarinic 1
chr20_+_1093905 0.319 NM_178578
PSMF1
proteasome (prosome, macropain) inhibitor subunit 1 (PI31)
chrM_-_9203 0.315


chr12_+_57610577 0.314 NM_007224
NXPH4
neurexophilin 4
chr11_+_59856136 0.312 NM_000139
MS4A2
membrane-spanning 4-domains, subfamily A, member 2 (Fc fragment of IgE, high affinity I, receptor for; beta polypeptide)
chr11_-_111749810 0.312 FDXACB1
ferredoxin-fold anticodon binding domain containing 1
chr20_-_62199106 0.310 NM_033405
PRIC285
peroxisomal proliferator-activated receptor A interacting complex 285
chr19_-_10514154 0.309 CDC37
cell division cycle 37 homolog (S. cerevisiae)
chr12_-_52779362 0.304 NM_033045
KRT84
keratin 84
chr19_+_55281262 0.304 NM_014218
KIR2DL1
KIR2DS4
killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1
killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 4
chr6_+_83072922 0.303 NM_006670
TPBG
trophoblast glycoprotein
chr10_+_94833646 0.302 NM_000783
CYP26A1
cytochrome P450, family 26, subfamily A, polypeptide 1
chr3_+_10857867 0.300 NM_014229
SLC6A11
solute carrier family 6 (neurotransmitter transporter, GABA), member 11
chr19_-_44285012 0.298 KCNN4
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr2_+_33661392 0.294 NM_170672
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr19_+_50084586 0.294 NM_000951
PRRG2
proline rich Gla (G-carboxyglutamic acid) 2

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.