Motif ID: SP1.p2

Z-value: 2.459


Transcription factors associated with SP1.p2:

Gene SymbolEntrez IDGene Name
SP1 6667 Sp1 transcription factor

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
SP1hg19_v1_chr12_+_53774422_53774427-0.252.9e-02Click!


Activity profile for motif SP1.p2.

activity profile for motif SP1.p2


Sorted Z-values histogram for motif SP1.p2

Sorted Z-values for motif SP1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SP1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chrX_+_43514157 24.460 MAOA
monoamine oxidase A
chr7_-_158380360 22.820 NM_002847
NM_130842
NM_130843
PTPRN2


protein tyrosine phosphatase, receptor type, N polypeptide 2


chr4_-_819879 19.275 NM_006651
CPLX1
complexin 1
chr19_-_54984341 18.155 NM_145057
CDC42EP5
CDC42 effector protein (Rho GTPase binding) 5
chr14_-_95786095 17.249 NM_024734
CLMN
calmin (calponin-like, transmembrane)
chr9_+_131183122 16.616 CERCAM
cerebral endothelial cell adhesion molecule
chr19_-_55658310 15.053 TNNT1
troponin T type 1 (skeletal, slow)
chr19_+_54371150 14.762 MYADM
myeloid-associated differentiation marker
chr19_+_54372659 14.684 NM_001020821
NM_001020818
MYADM

myeloid-associated differentiation marker

chr3_-_183979074 14.362 NM_033259
CAMK2N2
calcium/calmodulin-dependent protein kinase II inhibitor 2
chr3_+_99357439 14.218 NM_001850
NM_020351
COL8A1

collagen, type VIII, alpha 1

chr2_+_210288668 13.845 NM_001039538
MAP2
microtubule-associated protein 2
chr9_+_131183225 13.630 CERCAM
cerebral endothelial cell adhesion molecule
chr20_+_33146500 13.509 NM_032514
MAP1LC3A
microtubule-associated protein 1 light chain 3 alpha
chr1_+_3689308 13.485 NM_001163724
LOC388588
uncharacterized protein LOC388588
chr19_+_54371170 13.442 MYADM
myeloid-associated differentiation marker
chr19_-_49014832 12.991


chr19_-_2015628 12.968 NM_017797
BTBD2
BTB (POZ) domain containing 2
chr19_+_50094911 12.965 NM_020719
PRR12
proline rich 12
chr19_+_54371125 12.965 NM_001020819
NM_138373
MYADM

myeloid-associated differentiation marker

chr13_-_114018365 12.447 NM_024719
GRTP1
growth hormone regulated TBC protein 1
chr19_+_49622480 12.340 NM_003660
PPFIA3
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
chr19_-_46000159 12.246 NM_005619
NM_206900
RTN2

reticulon 2

chr15_-_65067696 12.098 NM_194272
RBPMS2
RNA binding protein with multiple splicing 2
chr16_-_3285359 11.960 NM_001145448
NM_198088
NM_001145446
NM_198087
ZNF200



zinc finger protein 200



chr17_+_81037504 11.633 NM_001004431
METRNL
meteorin, glial cell differentiation regulator-like
chr6_+_111804533 11.522 TRAF3IP2-AS1
TRAF3IP2 antisense RNA 1 (non-protein coding)
chr4_-_25864430 11.347 NM_015187
SEL1L3
sel-1 suppressor of lin-12-like 3 (C. elegans)
chr13_-_110438896 11.194 NM_003749
IRS2
insulin receptor substrate 2
chr21_-_44495894 11.121 NM_000071
CBS
cystathionine-beta-synthase
chr20_-_31071384 11.070 C20orf112
chromosome 20 open reading frame 112
chrX_-_1572648 11.055 NM_001173473
ASMTL
acetylserotonin O-methyltransferase-like
chr9_-_127533397 10.960 NM_001489
NM_033334
NR6A1

nuclear receptor subfamily 6, group A, member 1

chr22_-_39639967 10.956 PDGFB
platelet-derived growth factor beta polypeptide
chr11_-_65325632 10.931 NM_001130144
NM_001164266
NM_021070
LTBP3


latent transforming growth factor beta binding protein 3


chr19_+_49617611 10.914 NM_022165
LIN7B
lin-7 homolog B (C. elegans)
chr17_-_76921076 10.849 TIMP2
TIMP metallopeptidase inhibitor 2
chr12_+_53491448 10.819 IGFBP6
insulin-like growth factor binding protein 6
chr22_-_43116796 10.799 NM_017436
A4GALT
alpha 1,4-galactosyltransferase
chr21_+_44073650 10.759 NM_001001567
NM_001001568
NM_001001569
NM_001001570
NM_001001571
NM_001001572
NM_001001573
NM_001001574
NM_001001575
NM_001001576
NM_001001577
NM_001001578
NM_001001579
NM_001001580
NM_001001581
NM_001001582
NM_001001583
NM_001001584
NM_001001585
NM_002606
PDE9A



















phosphodiesterase 9A



















chr17_+_79989485 10.710 NM_005052
RAC3
ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
chr16_-_90085786 10.667 NM_001042610
DBNDD1
dysbindin (dystrobrevin binding protein 1) domain containing 1
chr12_+_53491417 10.613 NM_002178
IGFBP6
insulin-like growth factor binding protein 6
chr1_-_242687997 10.543 NM_152666
PLD5
phospholipase D family, member 5
chr1_+_955609 10.480 AGRN
agrin
chr22_+_24577443 10.347 NM_019601
SUSD2
sushi domain containing 2
chr17_-_66453561 10.318 NM_017983
WIPI1
WD repeat domain, phosphoinositide interacting 1
chr21_-_44496423 10.250 NM_001178008
NM_001178009
CBS

cystathionine-beta-synthase

chr19_+_54694118 10.195 NM_024075
TSEN34
tRNA splicing endonuclease 34 homolog (S. cerevisiae)
chr19_-_39368889 10.153 NM_001195833
NM_198445
RINL

Ras and Rab interactor-like

chr19_-_291335 10.126 NM_003712
NM_177526
PPAP2C

phosphatidic acid phosphatase type 2C

chr6_-_31698033 9.951 NM_013974
DDAH2
dimethylarginine dimethylaminohydrolase 2
chr2_-_96700662 9.926 NM_207328
GPAT2
glycerol-3-phosphate acyltransferase 2, mitochondrial
chrY_-_1522648 9.924 NM_001173473
ASMTL
acetylserotonin O-methyltransferase-like
chr3_-_128840343 9.891 RAB43
RAB43, member RAS oncogene family
chr9_+_103235634 9.855 TMEFF1
transmembrane protein with EGF-like and two follistatin-like domains 1
chr8_-_133493003 9.835 NM_004519
KCNQ3
potassium voltage-gated channel, KQT-like subfamily, member 3
chr1_+_87797301 9.810


chr9_+_131182690 9.803 NM_016174
CERCAM
cerebral endothelial cell adhesion molecule
chr9_+_35829375 9.769 NM_001042590
TMEM8B
transmembrane protein 8B
chr22_-_39548448 9.711 NM_175709
CBX7
chromobox homolog 7
chr19_+_41305100 9.685 EGLN2
egl nine homolog 2 (C. elegans)
chr19_-_291168 9.660 NM_177543
PPAP2C
phosphatidic acid phosphatase type 2C
chr19_+_45349584 9.642 PVRL2
poliovirus receptor-related 2 (herpesvirus entry mediator B)
chr12_-_49319211 9.619 NM_001143782
NM_016594
FKBP11

FK506 binding protein 11, 19 kDa

chr19_-_49622278 9.587 NM_018111
C19orf73
chromosome 19 open reading frame 73
chr17_-_80291903 9.582 NM_003004
SECTM1
secreted and transmembrane 1
chr4_+_2061238 9.567 NM_178557
NAT8L
N-acetyltransferase 8-like (GCN5-related, putative)
chr1_-_204120909 9.508 ETNK2
ethanolamine kinase 2
chr7_+_73868397 9.395 GTF2IRD1
GTF2I repeat domain containing 1
chr17_-_76921205 9.367 TIMP2
TIMP metallopeptidase inhibitor 2
chr19_+_49617631 9.356 LIN7B
lin-7 homolog B (C. elegans)
chr19_-_47922468 9.350 MEIS3
Meis homeobox 3
chr19_+_49468557 9.340 NM_000146
FTL
ferritin, light polypeptide
chr10_+_104155431 9.337 NM_002502
NFKB2
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr19_+_49468587 9.290 FTL
ferritin, light polypeptide
chr6_-_167040506 9.284 RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr8_+_22457098 9.266 NM_001013842
NM_001198827
NM_173686
C8orf58


chromosome 8 open reading frame 58


chr2_-_216300770 9.222 NM_002026
NM_054034
NM_212474
NM_212476
NM_212478
NM_212482
FN1





fibronectin 1





chr11_-_65325391 9.217 LTBP3
latent transforming growth factor beta binding protein 3
chr1_+_955468 9.192 NM_198576
AGRN
agrin
chr20_-_48099178 9.150 NM_004975
KCNB1
potassium voltage-gated channel, Shab-related subfamily, member 1
chr20_+_36531548 9.138 VSTM2L
V-set and transmembrane domain containing 2 like
chr16_+_82068830 9.124 NM_002153
HSD17B2
hydroxysteroid (17-beta) dehydrogenase 2
chr19_-_54693517 9.048 NM_001146056
NM_001146082
NM_001146083
NM_024298
MBOAT7



membrane bound O-acyltransferase domain containing 7



chr8_+_17354562 9.010 NM_001008539
SLC7A2
solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
chr22_+_50609159 8.991 NM_001160300
NM_052839
PANX2

pannexin 2

chr19_+_54369610 8.947 NM_001020820
MYADM
myeloid-associated differentiation marker
chr9_-_139890984 8.942 NM_004669
CLIC3
chloride intracellular channel 3
chr19_+_18747827 8.895 NM_018316
KLHL26
kelch-like 26 (Drosophila)
chr19_-_41196419 8.876 NM_004756
NUMBL
numb homolog (Drosophila)-like
chr19_-_55866063 8.786 NM_144613
COX6B2
cytochrome c oxidase subunit VIb polypeptide 2 (testis)
chr19_-_40971623 8.742 NM_000713
BLVRB
biliverdin reductase B (flavin reductase (NADPH))
chr19_+_55587220 8.719 NM_133180
EPS8L1
EPS8-like 1
chr3_+_54156573 8.717 CACNA2D3
calcium channel, voltage-dependent, alpha 2/delta subunit 3
chr18_-_65183922 8.688 NM_032160
DSEL
dermatan sulfate epimerase-like
chr8_-_145578502 8.684 NM_001252402
NM_001252404
C8ORFK29

uncharacterized LOC340393

chr19_+_12949258 8.681 NM_014975
MAST1
microtubule associated serine/threonine kinase 1
chr22_+_24577417 8.558 SUSD2
sushi domain containing 2
chr6_-_31697953 8.538 DDAH2
dimethylarginine dimethylaminohydrolase 2
chr19_+_41305333 8.524 NM_053046
EGLN2
egl nine homolog 2 (C. elegans)
chr2_+_54683276 8.412 NM_003128
SPTBN1
spectrin, beta, non-erythrocytic 1
chr19_+_56652689 8.402 ZNF444
zinc finger protein 444
chrX_+_43515406 8.392 NM_000240
MAOA
monoamine oxidase A
chr19_+_41305041 8.382 NM_080732
EGLN2
egl nine homolog 2 (C. elegans)
chr17_+_48351787 8.353 NM_153229
TMEM92
transmembrane protein 92
chr1_-_155162633 8.348 NM_001018016
NM_001018017
NM_001044390
NM_001044391
NM_001044392
NM_001044393
NM_001204285
NM_001204286
NM_001204287
NM_001204288
NM_001204289
NM_001204290
NM_001204291
NM_001204292
NM_001204293
NM_001204294
NM_001204295
NM_001204296
NM_001204297
NM_002456
MUC1



















mucin 1, cell surface associated



















chr22_-_50746000 8.308 NM_012401
PLXNB2
plexin B2
chr6_+_33378772 8.294 NM_002636
NM_024165
PHF1

PHD finger protein 1

chr22_-_22089975 8.279 NM_013313
YPEL1
yippee-like 1 (Drosophila)
chr13_-_114538953 8.261 NM_001143945
GAS6
growth arrest-specific 6
chr2_+_24299751 8.256 LOC375190
UPF0638 protein B
chr1_-_228135587 8.238 NM_003395
WNT9A
wingless-type MMTV integration site family, member 9A
chr11_+_65082288 8.207 NM_006779
CDC42EP2
CDC42 effector protein (Rho GTPase binding) 2
chr11_-_65640199 8.165 NM_016938
EFEMP2
EGF containing fibulin-like extracellular matrix protein 2
chr16_+_82068910 8.153 HSD17B2
hydroxysteroid (17-beta) dehydrogenase 2
chr19_-_56135934 8.150 NM_203374
ZNF784
zinc finger protein 784
chr17_+_26698986 8.142 NM_015077
SARM1
sterile alpha and TIR motif containing 1
chr12_-_117319231 8.124 NM_003806
HRK
harakiri, BCL2 interacting protein (contains only BH3 domain)
chr17_+_7788094 8.104 NM_001005271
CHD3
chromodomain helicase DNA binding protein 3
chr1_+_955536 8.080


chr2_-_218843541 8.066 TNS1
tensin 1
chr19_+_56652529 8.023 NM_001253792
NM_018337
ZNF444

zinc finger protein 444

chr19_+_41119476 8.003 LTBP4
latent transforming growth factor beta binding protein 4
chr6_-_167040700 7.991 NM_021135
RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr19_-_47922391 7.926 MEIS3
Meis homeobox 3
chr7_-_151329153 7.914 NM_024429
PRKAG2
protein kinase, AMP-activated, gamma 2 non-catalytic subunit
chr8_+_145064583 7.911 GRINA
glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
chr17_+_73521744 7.895 NM_001015002
NM_001031803
NM_004524
LLGL2


lethal giant larvae homolog 2 (Drosophila)


chr22_+_21319417 7.876 NM_001018060
NM_144704
AIFM3

apoptosis-inducing factor, mitochondrion-associated, 3

chr1_+_44457424 7.865 CCDC24
coiled-coil domain containing 24
chr20_+_36531498 7.832 NM_080607
VSTM2L
V-set and transmembrane domain containing 2 like
chr1_-_92949045 7.831 GFI1
growth factor independent 1 transcription repressor
chr2_+_28616360 7.829 FOSL2
FOS-like antigen 2
chrX_-_19140581 7.803 NM_001079858
NM_001079859
NM_001079860
NM_001184833
NM_001184834
NM_001184835
NM_001184836
NM_001184837
NM_005756
GPR64








G protein-coupled receptor 64








chr19_-_47922339 7.773 MEIS3
Meis homeobox 3
chr21_-_47648672 7.753 LSS
lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
chr1_-_3447974 7.724 MEGF6
multiple EGF-like-domains 6
chr6_-_31697568 7.691 DDAH2
dimethylarginine dimethylaminohydrolase 2
chr19_-_56135931 7.670 ZNF784
zinc finger protein 784
chr1_+_150521786 7.637 NM_019032
NM_025008
ADAMTSL4

ADAMTS-like 4

chr7_+_73868236 7.626 GTF2IRD1
GTF2I repeat domain containing 1
chr4_+_39046198 7.601 NM_001007075
NM_001171654
KLHL5

kelch-like 5 (Drosophila)

chr22_-_50708720 7.581 NM_002751
MAPK11
mitogen-activated protein kinase 11
chr2_-_216300444 7.566 FN1
fibronectin 1
chr14_+_103589711 7.556 TNFAIP2
tumor necrosis factor, alpha-induced protein 2
chr2_+_11886739 7.548 NM_145693
LPIN1
lipin 1
chr20_-_3154169 7.546 ProSAPiP1
ProSAPiP1 protein
chr19_+_54695103 7.537 NM_001077446
TSEN34
tRNA splicing endonuclease 34 homolog (S. cerevisiae)
chr19_+_41284161 7.537 RAB4B-EGLN2
RAB4B
RAB4B-EGLN2 readthrough
RAB4B, member RAS oncogene family
chr13_-_114897964 7.530 RASA3
RAS p21 protein activator 3
chr19_+_35521591 7.527 NM_001037
NM_199037
SCN1B

sodium channel, voltage-gated, type I, beta

chr9_+_139221931 7.480 NM_001145638
NM_015597
GPSM1

G-protein signaling modulator 1

chr1_-_204121144 7.468 NM_018208
ETNK2
ethanolamine kinase 2
chr11_-_2906960 7.459 NM_000076
NM_001122630
NM_001122631
CDKN1C


cyclin-dependent kinase inhibitor 1C (p57, Kip2)


chrX_-_1571733 7.434 NM_001173474
NM_004192
ASMTL

acetylserotonin O-methyltransferase-like

chrY_-_1521733 7.428 NM_001173474
NM_004192
ASMTL

acetylserotonin O-methyltransferase-like

chr8_+_57124314 7.424 NM_001011667
NM_001011668
NM_001011669
NM_001011670
NM_001011671
NM_024300
CHCHD7





coiled-coil-helix-coiled-coil-helix domain containing 7





chr8_+_57124321 7.398 CHCHD7
coiled-coil-helix-coiled-coil-helix domain containing 7
chr2_+_219264719 7.376 CTDSP1
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
chr21_-_47648715 7.347 NM_001001438
NM_001145436
NM_001145437
NM_002340
LSS



lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)



chr17_-_76124791 7.337 NM_001127198
TMC6
transmembrane channel-like 6
chr7_+_73868111 7.320 NM_001199207
NM_005685
NM_016328
GTF2IRD1


GTF2I repeat domain containing 1


chr17_-_77813049 7.320 NM_003655
CBX4
chromobox homolog 4
chr9_+_91606349 7.297 NM_005226
S1PR3
sphingosine-1-phosphate receptor 3
chr4_-_39528921 7.261 UGDH
UDP-glucose 6-dehydrogenase
chr16_+_89894853 7.241 NM_032451
SPIRE2
spire homolog 2 (Drosophila)
chr19_-_3028901 7.231 NM_003260
TLE2
transducin-like enhancer of split 2 (E(sp1) homolog, Drosophila)
chr11_+_819696 7.171 PNPLA2
patatin-like phospholipase domain containing 2
chr6_-_16761600 7.154 NM_000332
NM_001128164
ATXN1

ataxin 1

chr9_+_139560193 7.139 NM_201446
EGFL7
EGF-like-domain, multiple 7
chr6_-_167275997 7.117 RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chrX_+_43515531 7.093 MAOA
monoamine oxidase A
chr19_+_55851220 7.090 NM_032701
SUV420H2
suppressor of variegation 4-20 homolog 2 (Drosophila)
chr19_-_54693453 7.079 MBOAT7
membrane bound O-acyltransferase domain containing 7
chr7_-_95225802 7.070 NM_002612
PDK4
pyruvate dehydrogenase kinase, isozyme 4
chr9_+_35829208 7.059 NM_016446
NM_001042589
TMEM8B

transmembrane protein 8B

chr5_+_72416375 7.054 NM_001161342
NM_173490
TMEM171

transmembrane protein 171

chr8_+_145064238 7.051 GRINA
glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
chr19_+_39989603 7.028 DLL3
delta-like 3 (Drosophila)
chr19_+_49468656 7.020 FTL
ferritin, light polypeptide
chr3_-_127541160 7.017 NM_007283
MGLL
monoglyceride lipase
chrY_+_148060 7.012 NM_018390
PLCXD1
phosphatidylinositol-specific phospholipase C, X domain containing 1
chr8_-_144650884 7.011 C8orf73
chromosome 8 open reading frame 73
chr9_+_139886842 6.999 NM_183241
C9orf142
chromosome 9 open reading frame 142
chr12_-_49318663 6.996 NM_001143781
FKBP11
FK506 binding protein 11, 19 kDa
chr17_-_7166263 6.991 NM_001185023
NM_001307
CLDN7

claudin 7

chr5_+_2752261 6.976 NM_178569
C5orf38
chromosome 5 open reading frame 38
chr9_+_139560243 6.969 EGFL7
EGF-like-domain, multiple 7
chr14_+_105173953 6.967 INF2
inverted formin, FH2 and WH2 domain containing
chr19_+_41107220 6.965 NM_001042545
LTBP4
latent transforming growth factor beta binding protein 4
chr19_+_41116069 6.959


chr19_-_55574434 6.958 NM_001145971
RDH13
retinol dehydrogenase 13 (all-trans/9-cis)
chr18_+_55711388 6.947 NM_001144967
NM_001243960
NM_015277
NEDD4L


neural precursor cell expressed, developmentally down-regulated 4-like


chr19_+_47778099 6.907 NM_178511
PRR24
proline rich 24
chr19_+_55591759 6.903 NM_017729
EPS8L1
EPS8-like 1
chr7_+_43152196 6.897 NM_015052
HECW1
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
chr17_-_73840587 6.888 NM_199242
UNC13D
unc-13 homolog D (C. elegans)
chr17_+_7311501 6.867 NM_020795
NLGN2
neuroligin 2
chr6_-_30710219 6.863 NM_005803
FLOT1
flotillin 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
1.14 6.18e-11 GO:0008152 metabolic process
1.15 1.26e-09 GO:0044237 cellular metabolic process
1.14 7.22e-08 GO:0044238 primary metabolic process
1.35 9.87e-08 GO:0009966 regulation of signal transduction
1.29 5.33e-07 GO:0044281 small molecule metabolic process
1.29 2.56e-06 GO:0023051 regulation of signaling
1.07 4.99e-06 GO:0009987 cellular process
1.26 1.95e-05 GO:0006464 protein modification process
1.38 3.34e-05 GO:0055114 oxidation-reduction process
1.24 8.22e-05 GO:0043412 macromolecule modification
1.20 2.96e-04 GO:0044267 cellular protein metabolic process
1.27 5.29e-04 GO:0009056 catabolic process
1.21 6.71e-04 GO:0048523 negative regulation of cellular process
1.10 9.77e-04 GO:0050794 regulation of cellular process
1.46 2.57e-03 GO:0006066 alcohol metabolic process
1.19 3.16e-03 GO:0048519 negative regulation of biological process
1.08 4.62e-03 GO:0065007 biological regulation
1.30 5.43e-03 GO:0006629 lipid metabolic process
1.37 7.36e-03 GO:0007167 enzyme linked receptor protein signaling pathway
1.16 7.52e-03 GO:0019538 protein metabolic process
1.49 8.29e-03 GO:0051056 regulation of small GTPase mediated signal transduction
1.08 9.35e-03 GO:0050789 regulation of biological process
1.54 1.19e-02 GO:0030029 actin filament-based process
1.43 1.48e-02 GO:0044262 cellular carbohydrate metabolic process
1.58 1.61e-02 GO:0030036 actin cytoskeleton organization
1.49 1.65e-02 GO:0018193 peptidyl-amino acid modification
1.33 1.65e-02 GO:0016192 vesicle-mediated transport
1.31 1.83e-02 GO:0051128 regulation of cellular component organization
1.36 1.98e-02 GO:0005975 carbohydrate metabolic process
1.31 2.08e-02 GO:0031399 regulation of protein modification process
1.20 2.27e-02 GO:0048583 regulation of response to stimulus
1.26 2.51e-02 GO:0044248 cellular catabolic process
1.60 2.56e-02 GO:0048011 nerve growth factor receptor signaling pathway
1.57 2.59e-02 GO:0046578 regulation of Ras protein signal transduction
1.65 2.76e-02 GO:0019318 hexose metabolic process
1.73 3.18e-02 GO:0031344 regulation of cell projection organization
1.16 3.94e-02 GO:0048518 positive regulation of biological process
1.32 4.33e-02 GO:0042180 cellular ketone metabolic process
1.59 4.57e-02 GO:0005996 monosaccharide metabolic process

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
1.18 1.55e-29 GO:0005737 cytoplasm
1.24 2.04e-28 GO:0044444 cytoplasmic part
1.12 4.22e-27 GO:0005622 intracellular
1.12 1.67e-26 GO:0044424 intracellular part
1.12 5.29e-17 GO:0043226 organelle
1.12 1.22e-16 GO:0043229 intracellular organelle
1.13 1.83e-16 GO:0043227 membrane-bounded organelle
1.13 3.51e-16 GO:0043231 intracellular membrane-bounded organelle
1.29 1.26e-09 GO:0005829 cytosol
1.24 2.19e-06 GO:0031090 organelle membrane
1.13 4.68e-06 GO:0044422 organelle part
1.13 8.27e-06 GO:0044446 intracellular organelle part
1.61 1.56e-05 GO:0005773 vacuole
1.65 3.97e-05 GO:0000323 lytic vacuole
1.65 3.97e-05 GO:0005764 lysosome
1.88 4.02e-05 GO:0005912 adherens junction
1.83 4.12e-05 GO:0070161 anchoring junction
1.25 6.27e-05 GO:0012505 endomembrane system
1.29 2.17e-04 GO:0005783 endoplasmic reticulum
1.03 3.24e-04 GO:0044464 cell part
1.03 3.44e-04 GO:0005623 cell
1.30 6.65e-04 GO:0005794 Golgi apparatus
1.69 1.46e-03 GO:0031252 cell leading edge
1.89 1.81e-03 GO:0030055 cell-substrate junction
1.93 2.04e-03 GO:0005925 focal adhesion
1.88 3.65e-03 GO:0005924 cell-substrate adherens junction
1.23 4.94e-03 GO:0005739 mitochondrion
1.39 6.42e-03 GO:0000139 Golgi membrane
1.24 1.20e-02 GO:0000267 cell fraction
1.30 2.21e-02 GO:0042175 nuclear membrane-endoplasmic reticulum network
1.28 2.55e-02 GO:0044432 endoplasmic reticulum part
1.27 2.76e-02 GO:0005624 membrane fraction
1.31 3.11e-02 GO:0030054 cell junction
1.29 3.42e-02 GO:0005789 endoplasmic reticulum membrane
1.09 3.80e-02 GO:0005634 nucleus
1.31 4.00e-02 GO:0044431 Golgi apparatus part
1.26 4.34e-02 GO:0005626 insoluble fraction
1.85 4.65e-02 GO:0030027 lamellipodium

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
1.18 1.46e-20 GO:0005515 protein binding
1.20 7.55e-16 GO:0003824 catalytic activity
1.08 1.07e-10 GO:0005488 binding
1.61 1.32e-07 GO:0019904 protein domain specific binding
1.52 9.80e-07 GO:0008092 cytoskeletal protein binding
1.26 7.25e-06 GO:0016740 transferase activity
1.40 2.02e-05 GO:0019899 enzyme binding
1.36 1.32e-04 GO:0016301 kinase activity
1.37 2.93e-04 GO:0016491 oxidoreductase activity
1.13 4.70e-03 GO:0043169 cation binding
1.13 4.81e-03 GO:0043167 ion binding
1.29 5.88e-03 GO:0016772 transferase activity, transferring phosphorus-containing groups
1.48 7.52e-03 GO:0003779 actin binding
1.32 8.20e-03 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.12 1.36e-02 GO:0046872 metal ion binding
1.43 1.86e-02 GO:0003712 transcription cofactor activity
1.42 2.13e-02 GO:0000988 protein binding transcription factor activity
1.42 2.13e-02 GO:0000989 transcription factor binding transcription factor activity
1.38 2.28e-02 GO:0030695 GTPase regulator activity
1.68 2.58e-02 GO:0003714 transcription corepressor activity
1.78 3.75e-02 GO:0017124 SH3 domain binding
1.36 3.90e-02 GO:0060589 nucleoside-triphosphatase regulator activity
1.51 4.99e-02 GO:0019900 kinase binding