Motif ID: SOX17.p2

Z-value: 0.887


Transcription factors associated with SOX17.p2:

Gene SymbolEntrez IDGene Name
SOX17 64321 SRY (sex determining region Y)-box 17

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
SOX17hg19_v1_chr8_+_55370494_553705380.317.1e-03Click!


Activity profile for motif SOX17.p2.

activity profile for motif SOX17.p2


Sorted Z-values histogram for motif SOX17.p2

Sorted Z-values for motif SOX17.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of SOX17.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr15_-_48470453 5.930 NM_016132
MYEF2
myelin expression factor 2
chr3_-_48601200 5.726 NM_033199
UCN2
urocortin 2
chr14_-_23388380 5.526 NM_001077351
NM_001077352
NM_018107
RBM23


RNA binding motif protein 23


chr14_-_23388294 5.451 RBM23
RNA binding motif protein 23
chr19_+_36359346 5.337 NM_001024807
NM_005166
APLP1

amyloid beta (A4) precursor-like protein 1

chr14_-_23388359 5.285 RBM23
RNA binding motif protein 23
chr12_-_8815266 4.870 MFAP5
microfibrillar associated protein 5
chr5_+_140474198 4.857 NM_018936
PCDHB2
protocadherin beta 2
chr7_-_83270746 4.701 NM_001178129
SEMA3E
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
chr1_+_45792544 4.630 NM_032756
HPDL
4-hydroxyphenylpyruvate dioxygenase-like
chr17_-_46655544 4.438 NM_024015
HOXB4
homeobox B4
chr1_-_221915458 4.433 NM_007207
NM_144729
DUSP10

dual specificity phosphatase 10

chr1_-_221915393 4.323 DUSP10
dual specificity phosphatase 10
chr19_+_15160194 4.317 NM_012114
CASP14
caspase 14, apoptosis-related cysteine peptidase
chr1_-_151345156 4.296 NM_003944
SELENBP1
selenium binding protein 1
chr16_+_226678 4.179 NM_000558
HBA1
HBA2
hemoglobin, alpha 1
hemoglobin, alpha 2
chr12_-_8815370 4.083 NM_003480
MFAP5
microfibrillar associated protein 5
chr15_+_25230199 4.079 PAR5
Prader-Willi/Angelman syndrome-5
chr11_+_18720342 3.948 NM_153347
TMEM86A
transmembrane protein 86A
chr1_-_221915426 3.888 DUSP10
dual specificity phosphatase 10
chr17_-_39743085 3.807 NM_000526
KRT14
keratin 14
chr4_-_186732208 3.806 NM_001145671
SORBS2
sorbin and SH3 domain containing 2
chr15_-_48470319 3.801 MYEF2
myelin expression factor 2
chr17_-_78450247 3.737 NM_002522
NPTX1
neuronal pentraxin I
chr11_+_18720281 3.736 TMEM86A
transmembrane protein 86A
chr16_+_222845 3.734 NM_000517
HBA1
HBA2
hemoglobin, alpha 1
hemoglobin, alpha 2
chr8_-_20112691 3.597 NM_021020
LZTS1
leucine zipper, putative tumor suppressor 1
chr4_-_186732047 3.489 NM_001145672
SORBS2
sorbin and SH3 domain containing 2
chr12_-_8815479 3.465 MFAP5
microfibrillar associated protein 5
chr9_-_6645564 3.399 NM_000170
GLDC
glycine dehydrogenase (decarboxylating)
chrX_-_64196268 3.341 NM_001178033
NM_018684
ZC4H2

zinc finger, C4H2 domain containing

chr10_-_23633771 3.119 NM_153714
C10orf67
chromosome 10 open reading frame 67
chr16_+_30907927 3.033 NM_001142544
NM_001330
CTF1

cardiotrophin 1

chr10_+_12391728 3.022 CAMK1D
calcium/calmodulin-dependent protein kinase ID
chr15_-_45670624 3.016 GATM
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chrX_-_47931000 2.997 NM_001190255
ZNF630
zinc finger protein 630
chr5_+_76011780 2.980 NM_001992
F2R
coagulation factor II (thrombin) receptor
chr17_-_8113862 2.941 NM_004217
AURKB
aurora kinase B
chr8_-_119964059 2.926 NM_002546
TNFRSF11B
tumor necrosis factor receptor superfamily, member 11b
chr7_+_121513158 2.835 NM_001206838
NM_001206839
NM_002851
PTPRZ1


protein tyrosine phosphatase, receptor-type, Z polypeptide 1


chr5_-_64777703 2.825 NM_197941
ADAMTS6
ADAM metallopeptidase with thrombospondin type 1 motif, 6
chr5_-_24645084 2.748 NM_006727
CDH10
cadherin 10, type 2 (T2-cadherin)
chr3_-_99594915 2.710 NM_014890
FILIP1L
filamin A interacting protein 1-like
chr1_-_40367539 2.678 NM_001033081
NM_001033082
NM_005376
MYCL1


v-myc myelocytomatosis viral oncogene homolog 1, lung carcinoma derived (avian)


chr17_-_27948345 2.652 NM_032854
CORO6
coronin 6
chr1_-_156265395 2.635 NM_144580
C1orf85
chromosome 1 open reading frame 85
chr10_+_12391471 2.634 NM_020397
NM_153498
CAMK1D

calcium/calmodulin-dependent protein kinase ID

chr14_+_77228940 2.611 VASH1
vasohibin 1
chr9_+_90112754 2.596 NM_004938
DAPK1
death-associated protein kinase 1
chr12_-_59314297 2.568 LRIG3
leucine-rich repeats and immunoglobulin-like domains 3
chr17_-_16472463 2.525 NM_020653
ZNF287
zinc finger protein 287
chr6_+_26045611 2.472 NM_003531
HIST1H3C
histone cluster 1, H3c
chr6_-_134639195 2.467 NM_001143676
SGK1
serum/glucocorticoid regulated kinase 1
chr5_+_53751430 2.448 NM_006308
HSPB3
heat shock 27kDa protein 3
chr10_+_102729249 2.427 SEMA4G
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
chr6_-_134495944 2.381 SGK1
serum/glucocorticoid regulated kinase 1
chr17_-_74236272 2.377 NM_052916
RNF157
ring finger protein 157
chr12_-_59314069 2.349 NM_153377
LRIG3
leucine-rich repeats and immunoglobulin-like domains 3
chr4_+_184827805 2.341 STOX2
storkhead box 2
chr14_+_85996512 2.299 FLRT2
fibronectin leucine rich transmembrane protein 2
chr12_-_45270071 2.290 NELL2
NEL-like 2 (chicken)
chr11_-_94964209 2.273 NM_144665
SESN3
sestrin 3
chr7_+_89843133 2.227 NM_001040666
STEAP2
STEAP family member 2, metalloreductase
chr11_-_57417247 2.226 NM_145008
YPEL4
yippee-like 4 (Drosophila)
chr7_+_69064316 2.216 AUTS2
autism susceptibility candidate 2
chr1_+_35225341 2.194 NM_153212
GJB4
gap junction protein, beta 4, 30.3kDa
chr22_-_31686707 2.192 PIK3IP1
phosphoinositide-3-kinase interacting protein 1
chr14_+_85996454 2.185 NM_013231
FLRT2
fibronectin leucine rich transmembrane protein 2
chr16_-_30934437 2.185 FBXL19-AS1
FBXL19 antisense RNA 1 (non-protein coding)
chr2_-_220083658 2.159 ABCB6
ATP-binding cassette, sub-family B (MDR/TAP), member 6
chr2_-_45236521 2.153 NM_016932
SIX2
SIX homeobox 2
chr19_-_58514136 2.115 ZNF606
zinc finger protein 606
chr6_+_52529157 2.112 LOC730101
uncharacterized LOC730101
chr7_-_111846192 2.093 DOCK4
dedicator of cytokinesis 4
chr6_+_13925097 2.038 NM_001165032
NM_152737
RNF182

ring finger protein 182

chr2_+_27008881 2.038 NM_001809
NM_001042426
CENPA

centromere protein A

chr3_-_193272587 2.006 NM_032279
ATP13A4
ATPase type 13A4
chr2_+_27008912 1.998 CENPA
centromere protein A
chr10_+_12391708 1.997 CAMK1D
calcium/calmodulin-dependent protein kinase ID
chr11_-_70507911 1.995 NM_133266
SHANK2
SH3 and multiple ankyrin repeat domains 2
chr6_-_134496006 1.952 NM_005627
SGK1
serum/glucocorticoid regulated kinase 1
chr6_+_89791510 1.946 PNRC1
proline-rich nuclear receptor coactivator 1
chr5_+_50679239 1.945 ISL1
ISL LIM homeobox 1
chr3_+_52567983 1.935


chr5_-_146435589 1.927 NM_181674
NM_181676
PPP2R2B

protein phosphatase 2, regulatory subunit B, beta

chrX_+_49126326 1.926 PPP1R3F
protein phosphatase 1, regulatory subunit 3F
chr4_+_184827882 1.925


chr2_-_127977653 1.920 CYP27C1
cytochrome P450, family 27, subfamily C, polypeptide 1
chr9_+_126773851 1.912 NM_004789
LHX2
LIM homeobox 2
chr3_-_184971815 1.909 NM_001166415
NM_001966
EHHADH

enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase

chr6_+_80714389 1.905 TTK
TTK protein kinase
chr3_+_189349215 1.890 NM_001114978
NM_001114979
NM_003722
TP63


tumor protein p63


chr6_-_46138584 1.883 NM_021572
ENPP5
ectonucleotide pyrophosphatase/phosphodiesterase 5 (putative)
chr16_-_79634610 1.880 NM_001031804
NM_005360
MAF

v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian)

chr6_-_15248886 1.864


chr6_+_89790464 1.823 PNRC1
proline-rich nuclear receptor coactivator 1
chr6_+_89790412 1.817 NM_006813
PNRC1
proline-rich nuclear receptor coactivator 1
chr19_-_7553867 1.802 NM_080662
PEX11G
peroxisomal biogenesis factor 11 gamma
chr1_-_243418340 1.799 CEP170
centrosomal protein 170kDa
chr2_+_150187028 1.784 NM_194317
LYPD6
LY6/PLAUR domain containing 6
chr3_+_173116243 1.776 NM_014932
NLGN1
neuroligin 1
chr6_+_31430955 1.750 HCP5
HLA complex P5 (non-protein coding)
chr2_-_220083699 1.747 NM_005689
ABCB6
ATP-binding cassette, sub-family B (MDR/TAP), member 6
chr11_+_46402333 1.743 NM_001012334
MDK
midkine (neurite growth-promoting factor 2)
chr9_+_112403067 1.736 NM_001037293
PALM2
paralemmin 2
chr5_-_136834418 1.696 SPOCK1
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
chr17_+_67498391 1.680 MAP2K6
mitogen-activated protein kinase kinase 6
chr6_-_72130447 1.676 LINC00472
long intergenic non-protein coding RNA 472
chr7_-_111846384 1.663 NM_014705
DOCK4
dedicator of cytokinesis 4
chr1_-_26232890 1.661 NM_001145454
NM_005563
STMN1

stathmin 1

chr1_-_243418482 1.658 CEP170
centrosomal protein 170kDa
chr7_+_121513210 1.654 PTPRZ1
protein tyrosine phosphatase, receptor-type, Z polypeptide 1
chr7_-_150498362 1.648 NM_014020
TMEM176B
transmembrane protein 176B
chr1_-_156265457 1.643 C1orf85
chromosome 1 open reading frame 85
chr5_-_136834231 1.640 SPOCK1
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
chr1_-_243418675 1.629 NM_001042404
NM_001042405
NM_014812
CEP170


centrosomal protein 170kDa


chr12_-_45270157 1.617 NM_001145108
NM_006159
NELL2

NEL-like 2 (chicken)

chr7_-_14029286 1.617 ETV1
ets variant 1
chr6_-_152623213 1.604 SYNE1
spectrin repeat containing, nuclear envelope 1
chr14_+_65007163 1.599 NM_021979
HSPA2
heat shock 70kDa protein 2
chr9_+_4490193 1.594 NM_004170
SLC1A1
solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
chr3_+_111718006 1.584 NM_001008273
TAGLN3
transgelin 3
chr17_-_39728304 1.584 NM_000226
KRT9
keratin 9
chr6_+_39760148 1.580 NM_001201427
DAAM2
dishevelled associated activator of morphogenesis 2
chr17_-_7991020 1.576 NM_001139
ALOX12B
arachidonate 12-lipoxygenase, 12R type
chr11_-_125550674 1.572 NM_001612
NM_020069
NM_020107
NM_020108
ACRV1



acrosomal vesicle protein 1



chr5_-_146833150 1.569 NM_001387
DPYSL3
dihydropyrimidinase-like 3
chr5_+_140602914 1.562 NM_018934
PCDHB14
protocadherin beta 14
chr5_+_140593508 1.561 NM_018933
PCDHB13
protocadherin beta 13
chr10_+_17271276 1.559 VIM
vimentin
chr9_+_35673852 1.546 NM_001216
CA9
carbonic anhydrase IX
chr1_-_16539103 1.544 NM_153213
ARHGEF19
Rho guanine nucleotide exchange factor (GEF) 19
chr5_+_172484353 1.541 C5orf41
chromosome 5 open reading frame 41
chr13_+_53029614 1.532 CKAP2
cytoskeleton associated protein 2
chr17_+_74864427 1.528 NM_001199172
NM_144677
MGAT5B

mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isozyme B

chr4_-_186733372 1.528 NM_003603
NM_001145670
SORBS2

sorbin and SH3 domain containing 2

chr17_-_80656461 1.521 NM_006822
RAB40B
RAB40B, member RAS oncogene family
chr1_+_44115804 1.521 KDM4A
lysine (K)-specific demethylase 4A
chr19_-_17414083 1.520 NM_024527
ABHD8
abhydrolase domain containing 8
chr2_+_179316162 1.508 NM_001042702
DFNB59
deafness, autosomal recessive 59
chr4_-_186578122 1.506 NM_001145674
NM_001145675
SORBS2

sorbin and SH3 domain containing 2

chr10_+_17271277 1.502 VIM
vimentin
chr2_+_150186498 1.494 NM_001195685
LYPD6
LY6/PLAUR domain containing 6
chr11_-_70507944 1.494 SHANK2
SH3 and multiple ankyrin repeat domains 2
chr1_-_38512446 1.490 NM_002699
POU3F1
POU class 3 homeobox 1
chr4_-_48018609 1.479 CNGA1
cyclic nucleotide gated channel alpha 1
chr7_-_117513466 1.473 CTTNBP2
cortactin binding protein 2
chr8_-_22550708 1.472 NM_004430
EGR3
early growth response 3
chr16_+_8768403 1.461 NM_020686
ABAT
4-aminobutyrate aminotransferase
chr10_+_17271302 1.459 VIM
vimentin
chr4_-_2263706 1.451 NM_006454
MXD4
MAX dimerization protein 4
chr17_+_2699731 1.451 NM_001100398
NM_015085
RAP1GAP2

RAP1 GTPase activating protein 2

chr1_+_44115795 1.447 NM_014663
KDM4A
lysine (K)-specific demethylase 4A
chr1_-_205290756 1.444 NM_030952
NUAK2
NUAK family, SNF1-like kinase, 2
chr11_-_70507836 1.440 SHANK2
SH3 and multiple ankyrin repeat domains 2
chr19_-_6110561 1.438 NM_000635
NM_134433
RFX2

regulatory factor X, 2 (influences HLA class II expression)

chr10_+_99079017 1.438 NM_005479
FRAT1
frequently rearranged in advanced T-cell lymphomas
chrX_-_100446277 1.428 YWHAQP8
YWHAQ pseudogene 8
chr7_+_12727204 1.424 ARL4A
ADP-ribosylation factor-like 4A
chr10_+_46993545 1.422 NM_014696
GPRIN2
G protein regulated inducer of neurite outgrowth 2
chr8_+_86376130 1.416 NM_000067
CA2
carbonic anhydrase II
chr1_+_164528914 1.390 PBX1
pre-B-cell leukemia homeobox 1
chr5_-_137071703 1.385 NM_017415
KLHL3
kelch-like 3 (Drosophila)
chr15_-_45670955 1.372 NM_001482
GATM
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr6_-_28367499 1.370 NM_001163391
ZSCAN12
zinc finger and SCAN domain containing 12
chr17_-_48072566 1.352 NM_005220
DLX3
distal-less homeobox 3
chr16_-_30103204 1.351 NM_004608
TBX6
T-box 6
chr9_-_34522972 1.349 NM_198573
ENHO
energy homeostasis associated
chr1_+_44115828 1.337 KDM4A
lysine (K)-specific demethylase 4A
chr17_-_61777467 1.337 LIMD2
LIM domain containing 2
chr3_-_142607737 1.337 NM_013363
PCOLCE2
procollagen C-endopeptidase enhancer 2
chr22_-_44287806 1.335 NM_001177675
NM_138814
PNPLA5

patatin-like phospholipase domain containing 5

chr5_+_140213968 1.332 NM_018910
NM_031852
PCDHA7

protocadherin alpha 7

chr2_-_220083394 1.322 ABCB6
ATP-binding cassette, sub-family B (MDR/TAP), member 6
chrX_+_67913479 1.322 NM_001142504
STARD8
StAR-related lipid transfer (START) domain containing 8
chr10_-_61122219 1.307 NM_001001971
NM_001166698
NM_198215
FAM13C


family with sequence similarity 13, member C


chrX_-_51239295 1.299 NUDT11
nudix (nucleoside diphosphate linked moiety X)-type motif 11
chr6_-_111136616 1.292 CDK19
cyclin-dependent kinase 19
chr10_+_17271956 1.291 VIM
vimentin
chr3_-_99833348 1.289 NM_001042459
NM_182909
FILIP1L

filamin A interacting protein 1-like

chr10_+_17271859 1.289 VIM
vimentin
chr4_-_113437327 1.287 NM_024019
NEUROG2
neurogenin 2
chr1_+_160370363 1.282 NM_020335
VANGL2
vang-like 2 (van gogh, Drosophila)
chr2_-_216245573 1.272 FN1
fibronectin 1
chr3_+_186648515 1.272 ST6GAL1
ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
chr6_+_80714321 1.269 NM_001166691
NM_003318
TTK

TTK protein kinase

chr1_+_46972667 1.268 NM_147192
NM_172225
DMBX1

diencephalon/mesencephalon homeobox 1

chr15_-_44487468 1.266 FRMD5
FERM domain containing 5
chr8_-_124553448 1.263 NM_001242463
NM_058229
FBXO32

F-box protein 32

chr12_-_62997207 1.259 NM_175895
C12orf61
chromosome 12 open reading frame 61
chr20_+_55099784 1.257 NM_001012971
FAM209A
FAM209B
family with sequence similarity 209, member A
family with sequence similarity 209, member B
chr2_-_234763145 1.253 HJURP
Holliday junction recognition protein
chr4_-_2263808 1.241 MXD4
MAX dimerization protein 4
chr15_-_45493372 1.241 NM_138356
SHF
Src homology 2 domain containing F
chr1_+_43824598 1.226 NM_001255
CDC20
cell division cycle 20 homolog (S. cerevisiae)
chr6_+_39760138 1.226


chr17_+_46019022 1.221 PNPO
pyridoxamine 5'-phosphate oxidase
chr7_-_73256838 1.221 NM_152559
WBSCR27
Williams Beuren syndrome chromosome region 27
chr15_+_90118740 1.210 NM_152259
C15orf42
chromosome 15 open reading frame 42
chr1_-_45805606 1.204 NM_001048174
NM_001048172
NM_001048173
NM_001048171
NM_001128425
NM_012222
MUTYH





mutY homolog (E. coli)






Gene Ontology Analysis

Nothing significant found in process category.

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
1.72 1.14e-02 GO:0043228 non-membrane-bounded organelle
1.72 1.14e-02 GO:0043232 intracellular non-membrane-bounded organelle

Nothing significant found in function category.