Motif ID: RUNX1..3.p2

Z-value: 1.986


Transcription factors associated with RUNX1..3.p2:

Gene SymbolEntrez IDGene Name
RUNX1 861 runt-related transcription factor 1
RUNX2 860 runt-related transcription factor 2
RUNX3 864 runt-related transcription factor 3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
RUNX3hg19_v1_chr1_-_25256718_252567610.936.7e-34Click!
RUNX2hg19_v1_chr6_+_45390376_453904480.675.1e-11Click!
RUNX1hg19_v1_chr21_-_36421461_364214960.454.4e-05Click!


Activity profile for motif RUNX1..3.p2.

activity profile for motif RUNX1..3.p2


Sorted Z-values histogram for motif RUNX1..3.p2

Sorted Z-values for motif RUNX1..3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of RUNX1..3.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr19_-_51456159 12.190 NM_001077491
NM_001077492
NM_012427
KLK5


kallikrein-related peptidase 5


chr1_-_25291474 9.534 NM_001031680
RUNX3
runt-related transcription factor 3
chr8_-_143823823 9.001 NM_020427
SLURP1
secreted LY6/PLAUR domain containing 1
chr11_-_67448684 8.935 NM_001031615
ALDH3B2
aldehyde dehydrogenase 3 family, member B2
chr16_+_29674568 8.924 NM_003123
SPN
sialophorin
chr18_-_61329113 8.219 NM_006919
SERPINB3
serpin peptidase inhibitor, clade B (ovalbumin), member 3
chr16_+_29674564 7.563 SPN
sialophorin
chr10_+_5566923 7.490 NM_005185
CALML3
calmodulin-like 3
chr8_-_102803438 7.241 NM_032041
NCALD
neurocalcin delta
chr7_+_143140545 7.215 NM_177437
TAS2R60
taste receptor, type 2, member 60
chr12_-_114846191 7.085 NM_000192
NM_080717
TBX5

T-box 5

chr1_-_168513201 7.048 NM_003175
XCL1
XCL2
chemokine (C motif) ligand 1
chemokine (C motif) ligand 2
chr4_+_71091787 6.928 NM_152997
C4orf7
chromosome 4 open reading frame 7
chr4_-_69083797 6.719 NM_001129907
TMPRSS11BNL
TMPRSS11B N terminal-like
chr10_-_61122219 6.463 NM_001001971
NM_001166698
NM_198215
FAM13C


family with sequence similarity 13, member C


chrX_+_9431314 6.384 NM_001139466
NM_001139467
NM_001139468
TBL1X


transducin (beta)-like 1X-linked


chr3_-_150920946 6.319 NM_013308
GPR171
G protein-coupled receptor 171
chr1_-_203155745 6.198 CHI3L1
chitinase 3-like 1 (cartilage glycoprotein-39)
chr18_-_61311465 6.175 NM_002974
SERPINB4
serpin peptidase inhibitor, clade B (ovalbumin), member 4
chr19_-_9325546 6.101 NM_001005191
OR7D4
olfactory receptor, family 7, subfamily D, member 4
chr10_-_61122660 6.054 NM_001143773
FAM13C
family with sequence similarity 13, member C
chr6_+_30104509 5.893 NM_138700
TRIM40
tripartite motif containing 40
chr12_+_129338051 5.876 NM_144669
GLT1D1
glycosyltransferase 1 domain containing 1
chr15_+_73976537 5.832


chr16_-_68033355 5.690 NM_022355
DPEP2
dipeptidase 2
chr1_+_152691997 5.625 NM_001024679
C1orf68
chromosome 1 open reading frame 68
chr8_+_75736771 5.625 NM_015886
PI15
peptidase inhibitor 15
chr3_-_147124595 5.531 NM_001243256
NM_032153
ZIC4

Zic family member 4

chr7_-_14031049 5.501 NM_001163148
ETV1
ets variant 1
chr11_+_65647283 5.427 NM_001335
CTSW
cathepsin W
chr13_-_28674646 5.419 NM_004119
FLT3
fms-related tyrosine kinase 3
chr19_+_9361605 5.402 NM_001079935
OR7E24
olfactory receptor, family 7, subfamily E, member 24
chr1_-_161039703 5.318 ARHGAP30
Rho GTPase activating protein 30
chr6_-_165723074 5.307 NM_144980
C6orf118
chromosome 6 open reading frame 118
chr13_+_113741668 5.156 MCF2L
MCF.2 cell line derived transforming sequence-like
chr1_-_161039586 5.151 ARHGAP30
Rho GTPase activating protein 30
chr7_+_29234325 5.138 CHN2
chimerin (chimaerin) 2
chr8_-_134072404 5.113 NM_006748
SLA
Src-like-adaptor
chr2_+_27070962 5.097 NM_020134
NM_001253723
NM_001253724
DPYSL5


dihydropyrimidinase-like 5


chr1_-_203155827 5.083 CHI3L1
chitinase 3-like 1 (cartilage glycoprotein-39)
chr20_+_24449834 5.072 NM_024893
SYNDIG1
synapse differentiation inducing 1
chr1_+_66999805 5.052 NM_032291
SGIP1
SH3-domain GRB2-like (endophilin) interacting protein 1
chr8_-_102803196 5.051 NCALD
neurocalcin delta
chr11_-_6643809 5.018 DCHS1
dachsous 1 (Drosophila)
chrX_-_131261871 5.003 NM_194277
FRMD7
FERM domain containing 7
chr1_-_201346804 4.999 NM_000364
NM_001001430
NM_001001431
NM_001001432
TNNT2



troponin T type 2 (cardiac)



chr8_-_102803178 4.981 NCALD
neurocalcin delta
chr3_+_46919235 4.966 NM_000316
PTH1R
parathyroid hormone 1 receptor
chr11_-_119293848 4.926 THY1
Thy-1 cell surface antigen
chr7_-_14030864 4.921 NM_001163149
ETV1
ets variant 1
chr15_-_42342900 4.854 NM_001206670
PLA2G4E
phospholipase A2, group IVE
chr1_+_20617411 4.841 NM_001039500
VWA5B1
von Willebrand factor A domain containing 5B1
chr12_-_102872329 4.821 NM_001111284
IGF1
insulin-like growth factor 1 (somatomedin C)
chr17_+_73629513 4.808 NM_001162995
C17orf109
chromosome 17 open reading frame 109
chr1_-_161039649 4.797 ARHGAP30
Rho GTPase activating protein 30
chr16_+_23847271 4.789 NM_002738
NM_212535
PRKCB

protein kinase C, beta

chr5_-_76934508 4.784 NM_032109
OTP
orthopedia homeobox
chr11_+_124481451 4.751 NM_052959
PANX3
pannexin 3
chr21_-_40033617 4.744 NM_001243432
NM_001136154
NM_004449
ERG


v-ets erythroblastosis virus E26 oncogene homolog (avian)


chrX_-_30595883 4.719 NM_025159
CXorf21
chromosome X open reading frame 21
chr1_-_34630856 4.706 CSMD2
CUB and Sushi multiple domains 2
chr10_-_105238996 4.687 NM_001129742
CALHM3
calcium homeostasis modulator 3
chr1_+_152748847 4.618 NM_178354
LCE1F
late cornified envelope 1F
chr1_-_203155867 4.613 CHI3L1
chitinase 3-like 1 (cartilage glycoprotein-39)
chr6_-_31846816 4.608 NM_001178044
NM_025257
SLC44A4

solute carrier family 44, member 4

chr17_+_32582295 4.593 NM_002982
CCL2
chemokine (C-C motif) ligand 2
chr15_-_65503786 4.580 NM_003613
CILP
cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
chr1_+_168545710 4.577 NM_002995
XCL1
chemokine (C motif) ligand 1
chr19_+_51293671 4.545 NM_033068
ACPT
acid phosphatase, testicular
chr18_-_31802433 4.544 NM_001198547
NOL4
nucleolar protein 4
chr1_+_17634689 4.538 NM_012387
PADI4
peptidyl arginine deiminase, type IV
chr11_+_1889902 4.522 NM_001013253
LSP1
lymphocyte-specific protein 1
chr11_-_31825593 4.513 PAX6
paired box 6
chr1_-_203155910 4.465 NM_001276
CHI3L1
chitinase 3-like 1 (cartilage glycoprotein-39)
chr3_+_42947401 4.462 NM_207404
ZNF662
zinc finger protein 662
chr17_-_79919056 4.456 NM_178493
NOTUM
notum pectinacetylesterase homolog (Drosophila)
chr6_+_31540092 4.452 NM_000595
LTA
lymphotoxin alpha (TNF superfamily, member 1)
chr11_-_74442429 4.449 CHRDL2
chordin-like 2
chr1_-_184006491 4.419 GLT25D2
glycosyltransferase 25 domain containing 2
chr6_+_27925018 4.417 NM_012367
OR2B6
olfactory receptor, family 2, subfamily B, member 6
chr1_-_217250230 4.398 NM_001243507
NM_001243509
ESRRG

estrogen-related receptor gamma

chr16_-_10788729 4.392 NM_144674
TEKT5
tektin 5
chr1_-_203155813 4.347 CHI3L1
chitinase 3-like 1 (cartilage glycoprotein-39)
chr1_-_34631442 4.342 NM_052896
CSMD2
CUB and Sushi multiple domains 2
chr7_+_120628867 4.302 C7orf58
chromosome 7 open reading frame 58
chr2_+_204571379 4.300 CD28
CD28 molecule
chr1_-_161039745 4.299 NM_001025598
NM_181720
ARHGAP30

Rho GTPase activating protein 30

chr12_+_15125955 4.289 NM_006205
PDE6H
phosphodiesterase 6H, cGMP-specific, cone, gamma
chr4_-_174450529 4.287 HAND2
heart and neural crest derivatives expressed 2
chr6_+_31539875 4.285 NM_001159740
LTA
lymphotoxin alpha (TNF superfamily, member 1)
chr1_+_32716839 4.272 NM_005356
LCK
lymphocyte-specific protein tyrosine kinase
chr4_-_10686314 4.271 NM_052964
CLNK
cytokine-dependent hematopoietic cell linker
chr19_-_54761057 4.269 NM_001081442
NM_001081443
NM_006840
LILRB5


leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 5


chr6_-_31846751 4.262 SLC44A4
solute carrier family 44, member 4
chr5_-_76934373 4.251 OTP
orthopedia homeobox
chr17_-_34524054 4.219 NM_001001437
NM_021006
CCL3L3
CCL3
CCL3L1
chemokine (C-C motif) ligand 3-like 3
chemokine (C-C motif) ligand 3
chemokine (C-C motif) ligand 3-like 1
chr20_-_49308074 4.203


chr15_-_50558161 4.192 NM_002112
HDC
histidine decarboxylase
chr6_-_31846766 4.191 SLC44A4
solute carrier family 44, member 4
chr20_+_16728997 4.184 NM_020157
OTOR
otoraplin
chr9_-_130540911 4.158 NM_170600
SH2D3C
SH2 domain containing 3C
chr16_+_29674282 4.149 NM_001030288
SPN
sialophorin
chr2_-_217560247 4.135 NM_000599
IGFBP5
insulin-like growth factor binding protein 5
chr4_+_119948273 4.108 SYNPO2
synaptopodin 2
chr1_+_203734283 4.106 NM_001136190
NM_017773
LAX1

lymphocyte transmembrane adaptor 1

chr3_+_147127151 4.103 NM_003412
ZIC1
Zic family member 1
chr22_+_37257004 4.073 NM_000631
NM_013416
NCF4

neutrophil cytosolic factor 4, 40kDa

chr1_+_108992903 4.071 NM_001143987
NM_001143988
NBPF4
NBPF6

neuroblastoma breakpoint family, member 4
neuroblastoma breakpoint family, member 6

chr7_+_120628722 4.067 NM_024913
C7orf58
chromosome 7 open reading frame 58
chr12_+_25205488 4.062 LRMP
lymphoid-restricted membrane protein
chr2_-_222436996 4.053 NM_004438
EPHA4
EPH receptor A4
chr11_+_120531027 4.051 NM_014619
GRIK4
glutamate receptor, ionotropic, kainate 4
chr11_+_4660944 4.044 NM_001004751
OR51D1
olfactory receptor, family 51, subfamily D, member 1
chr20_-_25062756 4.044 NM_014588
NM_199425
VSX1

visual system homeobox 1

chr4_-_174450343 4.027 HAND2
heart and neural crest derivatives expressed 2
chr7_+_29234111 4.026 NM_004067
CHN2
chimerin (chimaerin) 2
chrX_+_151927733 3.999 NM_001129828
NM_001129826
NM_001080848
NM_004909
CSAG3

CSAG2

CSAG family, member 3

CSAG family, member 2

chr19_+_17634109 3.994 NM_001098524
NM_173544
FAM129C

family with sequence similarity 129, member C

chr3_-_170744458 3.991 SLC2A2
solute carrier family 2 (facilitated glucose transporter), member 2
chrX_-_15332680 3.988 NM_001012428
ASB11
ankyrin repeat and SOCS box containing 11
chr2_+_234826042 3.983 NM_024080
TRPM8
transient receptor potential cation channel, subfamily M, member 8
chr1_-_203317366 3.983 FMOD
fibromodulin
chr9_-_95166827 3.978 NM_014057
NM_033014
OGN

osteoglycin

chr7_-_126892304 3.952 NM_001127323
GRM8
glutamate receptor, metabotropic 8
chr3_+_42947649 3.935 NM_001134656
ZNF662
zinc finger protein 662
chr1_+_172628157 3.927 NM_000639
FASLG
Fas ligand (TNF superfamily, member 6)
chr11_-_75379113 3.925 MAP6
microtubule-associated protein 6
chr15_+_74422589 3.923 NM_001130138
ISLR2
immunoglobulin superfamily containing leucine-rich repeat 2
chr2_+_103035148 3.891 NM_003853
IL18RAP
interleukin 18 receptor accessory protein
chr2_+_204571197 3.851 NM_001243077
NM_001243078
NM_006139
CD28


CD28 molecule


chr19_-_3786221 3.838 MATK
megakaryocyte-associated tyrosine kinase
chr1_-_160832466 3.836 NM_001166663
NM_001166664
NM_016382
CD244


CD244 molecule, natural killer cell receptor 2B4


chr19_-_14048877 3.835 PODNL1
podocan-like 1
chr5_-_160112266 3.827 ATP10B
ATPase, class V, type 10B
chr14_-_24977421 3.821 NM_001836
CMA1
chymase 1, mast cell
chr16_+_855442 3.815 NM_001013638
PRR25
proline rich 25
chr1_+_198608216 3.801 PTPRC
protein tyrosine phosphatase, receptor type, C
chr4_+_119948554 3.793 SYNPO2
synaptopodin 2
chr18_+_66465316 3.793 NM_024781
CCDC102B
coiled-coil domain containing 102B
chr7_-_92848837 3.790 NM_198151
HEPACAM2
HEPACAM family member 2
chr6_+_35748820 3.779 NM_001010886
C6orf127
chromosome 6 open reading frame 127
chr2_-_26700909 3.767 NM_004802
NM_194322
NM_194323
OTOF


otoferlin


chr12_+_49372235 3.763 NM_005430
WNT1
wingless-type MMTV integration site family, member 1
chr12_+_7917811 3.746 NM_001145465
NANOGNB
NANOG neighbor homeobox
chr1_-_240775448 3.723 NM_022469
GREM2
gremlin 2
chr1_+_86889768 3.714 NM_006536
CLCA2
chloride channel accessory 2
chr6_-_34524083 3.706 NM_001252294
NM_012391
SPDEF

SAM pointed domain containing ets transcription factor

chrX_+_48542159 3.704 NM_000377
WAS
Wiskott-Aldrich syndrome (eczema-thrombocytopenia)
chrX_-_151877669 3.703 NM_001129826
NM_001129828
NM_001080848
NM_004909
CSAG3

CSAG2

CSAG family, member 3

CSAG family, member 2

chrX_+_71130619 3.700 NM_001013627
NHSL2
NHS-like 2
chr2_-_127977653 3.697 CYP27C1
cytochrome P450, family 27, subfamily C, polypeptide 1
chr4_+_8951476 3.679 NM_001040071
LOC650293
seven transmembrane helix receptor
chr8_+_24151579 3.668 NM_014265
NM_021777
ADAM28

ADAM metallopeptidase domain 28

chr1_+_158323485 3.656 NM_001042583
NM_001042584
NM_001042585
NM_001042586
NM_001042587
NM_001185107
NM_001185108
NM_001185110
NM_001185112
NM_001185113
NM_001185114
NM_001185115
NM_030893
CD1E












CD1e molecule












chr17_-_72542244 3.654 NM_006678
CD300C
CD300c molecule
chr2_-_21230572 3.635 APOB
apolipoprotein B (including Ag(x) antigen)
chr9_-_130517552 3.626 NM_001142534
NM_001142533
SH2D3C

SH2 domain containing 3C

chr6_-_41168923 3.626 NM_024807
TREML2
triggering receptor expressed on myeloid cells-like 2
chr12_+_93130264 3.611 NM_001004330
PLEKHG7
pleckstrin homology domain containing, family G (with RhoGef domain) member 7
chr10_-_103540125 3.604 NM_001206389
FGF8
fibroblast growth factor 8 (androgen-induced)
chr2_+_85921413 3.603 NM_006433
NM_012483
GNLY

granulysin

chr4_+_88896899 3.596 SPP1
secreted phosphoprotein 1
chr13_-_103054027 3.594 NM_175929
FGF14
fibroblast growth factor 14
chr6_-_128222175 3.584 NM_001010923
NM_001164685
THEMIS

thymocyte selection associated

chr15_+_58724174 3.579 NM_000236
LIPC
lipase, hepatic
chr11_+_4470524 3.574 NM_001005172
OR52K2
olfactory receptor, family 52, subfamily K, member 2
chr9_-_116840545 3.572 AMBP
alpha-1-microglobulin/bikunin precursor
chr7_-_44228880 3.571 NM_000162
GCK
glucokinase (hexokinase 4)
chr3_-_114343052 3.570 NM_001164347
ZBTB20
zinc finger and BTB domain containing 20
chr1_-_161039413 3.565 ARHGAP30
Rho GTPase activating protein 30
chr21_+_45875368 3.558 NM_030891
LRRC3
leucine rich repeat containing 3
chr2_+_204732509 3.557 NM_001037631
NM_005214
CTLA4

cytotoxic T-lymphocyte-associated protein 4

chr17_-_56606710 3.553 NM_004574
SEPT4
septin 4
chr2_+_202671197 3.551 NM_139158
CDK15
cyclin-dependent kinase 15
chr1_-_156675237 3.545 NM_001878
NM_001199723
CRABP2

cellular retinoic acid binding protein 2

chr4_+_646965 3.539 NM_001145292
PDE6B
phosphodiesterase 6B, cGMP-specific, rod, beta
chrX_-_6146655 3.537 NM_181332
NLGN4X
neuroligin 4, X-linked
chr8_-_27941387 3.536 NM_001010906
C8orf80
chromosome 8 open reading frame 80
chr6_-_36304584 3.523 NM_001010903
C6orf222
chromosome 6 open reading frame 222
chr4_-_71532341 3.517 NM_144646
IGJ
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr14_-_94423766 3.517 NM_016150
ASB2
ankyrin repeat and SOCS box containing 2
chr6_+_116850175 3.513 NM_153036
FAM26D
family with sequence similarity 26, member D
chr1_-_201346783 3.513 TNNT2
troponin T type 2 (cardiac)
chr1_-_42501573 3.505 HIVEP3
human immunodeficiency virus type I enhancer binding protein 3
chr14_-_106780535 3.492 IGHA1
IGHA2
IGHD
IGHG1
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant alpha 2 (A2m marker)
immunoglobulin heavy constant delta
immunoglobulin heavy constant gamma 1 (G1m marker)
chr6_+_72926462 3.479 NM_001168410
RIMS1
regulating synaptic membrane exocytosis 1
chr3_-_170744767 3.469 NM_000340
SLC2A2
solute carrier family 2 (facilitated glucose transporter), member 2
chr11_+_124120422 3.463 NM_001002905
OR8G1
olfactory receptor, family 8, subfamily G, member 1
chr19_-_14049167 3.462 NM_024825
PODNL1
podocan-like 1
chr1_+_198608136 3.461 NM_002838
NM_080921
NM_080923
PTPRC


protein tyrosine phosphatase, receptor type, C


chr11_-_124622133 3.452 VSIG2
V-set and immunoglobulin domain containing 2
chr18_-_31803168 3.438 NOL4
nucleolar protein 4
chr1_+_110655061 3.428 NM_203412
UBL4B
ubiquitin-like 4B
chr2_-_42720476 3.423 KCNG3
potassium voltage-gated channel, subfamily G, member 3
chr17_-_72542148 3.421 CD300C
CD300c molecule
chr18_+_61575203 3.413 SERPINB10
serpin peptidase inhibitor, clade B (ovalbumin), member 10
chr3_+_100328432 3.404 NM_032787
GPR128
G protein-coupled receptor 128
chr11_-_5275904 3.400 NM_000184
HBG1
HBG2
hemoglobin, gamma A
hemoglobin, gamma G
chr8_+_85095702 3.397 RALYL
RALY RNA binding protein-like
chr1_+_152850797 3.387 NM_030663
SMCP
sperm mitochondria-associated cysteine-rich protein

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
1.51 1.99e-12 GO:0032501 multicellular organismal process
1.43 1.18e-11 GO:0050896 response to stimulus
2.25 3.68e-11 GO:0002376 immune system process
1.92 7.11e-09 GO:0003008 system process
1.52 1.06e-07 GO:0023052 signaling
1.92 1.32e-06 GO:0050877 neurological system process
2.58 7.38e-06 GO:0001775 cell activation
2.24 8.45e-06 GO:0007267 cell-cell signaling
1.50 8.81e-06 GO:0007165 signal transduction
1.72 1.70e-05 GO:0007166 cell surface receptor linked signaling pathway
4.74 6.71e-05 GO:0002683 negative regulation of immune system process
2.14 9.85e-05 GO:0006955 immune response
3.13 1.06e-04 GO:0050865 regulation of cell activation
3.45 1.26e-04 GO:0046649 lymphocyte activation
2.03 2.96e-04 GO:0007600 sensory perception
7.99 4.57e-04 GO:0050777 negative regulation of immune response
1.77 7.56e-04 GO:0051239 regulation of multicellular organismal process
1.88 8.34e-04 GO:0007154 cell communication
5.45 1.02e-03 GO:0050866 negative regulation of cell activation
1.92 1.58e-03 GO:0009611 response to wounding
2.91 2.04e-03 GO:0002694 regulation of leukocyte activation
3.48 2.33e-03 GO:0002697 regulation of immune effector process
2.89 2.41e-03 GO:0045321 leukocyte activation
5.48 2.64e-03 GO:0002695 negative regulation of leukocyte activation
2.96 3.93e-03 GO:0051249 regulation of lymphocyte activation
1.57 4.99e-03 GO:0048583 regulation of response to stimulus
2.51 5.07e-03 GO:0051240 positive regulation of multicellular organismal process
12.78 5.22e-03 GO:0032715 negative regulation of interleukin-6 production
1.44 5.37e-03 GO:0048731 system development
1.34 5.63e-03 GO:0051716 cellular response to stimulus
1.94 7.07e-03 GO:0007155 cell adhesion
1.94 7.07e-03 GO:0022610 biological adhesion
2.17 7.67e-03 GO:0008284 positive regulation of cell proliferation
4.02 1.71e-02 GO:0001818 negative regulation of cytokine production
5.56 1.76e-02 GO:0002700 regulation of production of molecular mediator of immune response
5.56 1.76e-02 GO:0032675 regulation of interleukin-6 production
1.86 2.05e-02 GO:0048584 positive regulation of response to stimulus
2.05 2.88e-02 GO:0007186 G-protein coupled receptor protein signaling pathway
3.62 3.08e-02 GO:0050727 regulation of inflammatory response
2.11 3.14e-02 GO:0019226 transmission of nerve impulse
2.11 3.14e-02 GO:0035637 multicellular organismal signaling
1.90 3.56e-02 GO:0002682 regulation of immune system process
2.18 3.63e-02 GO:0007268 synaptic transmission
3.11 3.84e-02 GO:0050900 leukocyte migration
1.35 4.09e-02 GO:0007275 multicellular organismal development

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
2.08 3.25e-17 GO:0005576 extracellular region
1.65 2.31e-16 GO:0005886 plasma membrane
1.64 3.60e-16 GO:0071944 cell periphery
2.61 3.27e-12 GO:0005615 extracellular space
2.35 7.21e-12 GO:0044421 extracellular region part
2.06 2.37e-09 GO:0031226 intrinsic to plasma membrane
2.05 4.65e-09 GO:0005887 integral to plasma membrane
1.38 2.61e-08 GO:0031224 intrinsic to membrane
4.63 3.32e-08 GO:0009897 external side of plasma membrane
1.37 3.26e-07 GO:0016021 integral to membrane
2.87 3.27e-07 GO:0009986 cell surface
1.66 5.48e-07 GO:0044459 plasma membrane part
1.31 1.19e-06 GO:0044425 membrane part
1.22 1.02e-04 GO:0016020 membrane
2.20 9.60e-03 GO:0031012 extracellular matrix
2.17 4.73e-02 GO:0005578 proteinaceous extracellular matrix

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
1.94 2.04e-10 GO:0004872 receptor activity
1.80 1.26e-09 GO:0004871 signal transducer activity
1.80 1.26e-09 GO:0060089 molecular transducer activity
1.94 2.91e-07 GO:0004888 transmembrane receptor activity
2.01 2.08e-06 GO:0005102 receptor binding
3.16 2.46e-04 GO:0005125 cytokine activity
1.90 8.11e-04 GO:0004930 G-protein coupled receptor activity
5.68 2.90e-03 GO:0019825 oxygen binding
2.97 5.38e-03 GO:0001664 G-protein-coupled receptor binding
2.24 7.38e-03 GO:0030246 carbohydrate binding
5.75 7.49e-03 GO:0003823 antigen binding
9.58 8.04e-03 GO:0019865 immunoglobulin binding
3.12 2.12e-02 GO:0046906 tetrapyrrole binding
2.70 3.35e-02 GO:0005126 cytokine receptor binding
3.12 3.67e-02 GO:0020037 heme binding
2.08 4.05e-02 GO:0005216 ion channel activity
4.69 4.11e-02 GO:0005070 SH3/SH2 adaptor activity
3.22 4.33e-02 GO:0008201 heparin binding