Motif ID: RREB1.p2

Z-value: 2.232


Transcription factors associated with RREB1.p2:

Gene SymbolEntrez IDGene Name
RREB1 6239 ras responsive element binding protein 1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
RREB1hg19_v1_chr6_+_7108864_71089430.403.6e-04Click!


Activity profile for motif RREB1.p2.

activity profile for motif RREB1.p2


Sorted Z-values histogram for motif RREB1.p2

Sorted Z-values for motif RREB1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of RREB1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chrX_+_102632108 51.165 NM_014380
NGFRAP1
nerve growth factor receptor (TNFRSF16) associated protein 1
chrX_+_102631408 42.892 NGFRAP1
nerve growth factor receptor (TNFRSF16) associated protein 1
chrX_-_48693934 35.912 NM_013271
PCSK1N
proprotein convertase subtilisin/kexin type 1 inhibitor
chr11_-_125366048 28.137 NM_005103
NM_022549
FEZ1

fasciculation and elongation protein zeta 1 (zygin I)

chr3_-_48632592 21.962 NM_000094
COL7A1
collagen, type VII, alpha 1
chr17_-_33700619 19.977 NM_001104587
NM_001104588
NM_001104589
NM_001104590
NM_152270
SLFN11




schlafen family member 11




chr19_-_51456159 18.799 NM_001077491
NM_001077492
NM_012427
KLK5


kallikrein-related peptidase 5


chr5_+_156887204 18.291 NIPAL4
NIPA-like domain containing 4
chr20_+_44637539 17.371 NM_004994
MMP9
matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
chr17_-_46655544 16.303 NM_024015
HOXB4
homeobox B4
chr16_-_4588379 16.054 NM_001199054
C16orf5
chromosome 16 open reading frame 5
chr8_+_58906968 15.246 NM_147189
FAM110B
family with sequence similarity 110, member B
chrX_+_134555867 14.419 LINC00086
long intergenic non-protein coding RNA 86
chr19_-_17007674 13.750 CPAMD8
C3 and PZP-like, alpha-2-macroglobulin domain containing 8
chr2_+_42275017 12.983 NM_138370
PKDCC
protein kinase domain containing, cytoplasmic homolog (mouse)
chr16_-_4588738 12.523 NM_001199055
NM_001199056
NM_013399
C16orf5


chromosome 16 open reading frame 5


chr20_-_1165116 12.324 NM_018354
TMEM74B
transmembrane protein 74B
chr21_-_45682098 12.213 NM_013369
NM_175867
DNMT3L

DNA (cytosine-5-)-methyltransferase 3-like

chr20_+_327725 11.936 NRSN2
neurensin 2
chr20_+_45523247 11.654 NM_005244
NM_172110
EYA2

eyes absent homolog 2 (Drosophila)

chr2_-_128432642 11.645 NM_001136037
NM_001161403
LIMS2

LIM and senescent cell antigen-like domains 2

chr12_-_133532847 11.629 NM_183238
NM_001164715
ZNF605

zinc finger protein 605

chrX_-_119249774 11.589 NM_139282
RHOXF1
Rhox homeobox family, member 1
chr2_-_97560855 11.341 NM_001172667
FAM178B
family with sequence similarity 178, member B
chr14_-_21493910 11.060 NM_016250
NM_201535
NM_201536
NM_201537
NDRG2



NDRG family member 2



chr14_-_21493858 10.893 NDRG2
NDRG family member 2
chr3_+_192958892 10.769 NM_020386
HRASLS
HRAS-like suppressor
chr2_+_48757063 10.547 NM_001198593
STON1-GTF2A1L
STON1-GTF2A1L readthrough
chr16_-_325867 10.399 NM_003834
NM_183337
RGS11

regulator of G-protein signaling 11

chr2_+_219745243 10.091 NM_025216
WNT10A
wingless-type MMTV integration site family, member 10A
chr5_+_6448735 10.016 NM_001145161
UBE2QL1
ubiquitin-conjugating enzyme E2Q family-like 1
chr12_-_54982271 9.855 NM_006741
PPP1R1A
protein phosphatase 1, regulatory (inhibitor) subunit 1A
chr19_-_18548788 9.503 NM_001170939
ISYNA1
inositol-3-phosphate synthase 1
chr14_-_21493122 9.482 NM_201538
NM_201539
NM_201540
NM_201541
NDRG2



NDRG family member 2



chr15_-_48470453 8.841 NM_016132
MYEF2
myelin expression factor 2
chr19_+_8274179 8.801 NM_024552
CERS4
ceramide synthase 4
chr10_-_135150474 8.782 NM_015722
CALY
calcyon neuron-specific vesicular protein
chr19_-_8675559 8.771 NM_030957
ADAMTS10
ADAM metallopeptidase with thrombospondin type 1 motif, 10
chr17_+_29248697 8.738 NM_018404
ADAP2
ArfGAP with dual PH domains 2
chr9_+_131870105 8.719


chr5_-_102898450 8.490 NM_031438
NUDT12
nudix (nucleoside diphosphate linked moiety X)-type motif 12
chr1_-_24513737 8.361 NM_170743
NM_173064
NM_173065
IL28RA


interleukin 28 receptor, alpha (interferon, lambda receptor)


chr17_-_7991020 8.332 NM_001139
ALOX12B
arachidonate 12-lipoxygenase, 12R type
chr2_-_163695028 8.311 KCNH7
potassium voltage-gated channel, subfamily H (eag-related), member 7
chrX_-_151306959 8.307 NM_001204811
NM_001011543
NM_001251828
NM_021048
MAGEA10-MAGEA5
MAGEA10


MAGEA10-MAGEA5 readthrough
melanoma antigen family A, 10


chr5_-_111093251 8.180 NM_001142479
NM_001142480
NM_001142478
C5orf13


chromosome 5 open reading frame 13


chr10_-_135150368 8.071 CALY
calcyon neuron-specific vesicular protein
chr20_+_44746948 8.070 CD40
CD40 molecule, TNF receptor superfamily member 5
chrX_-_151938194 8.030 NM_005362
MAGEA3
melanoma antigen family A, 3
chr12_-_53074172 7.937 NM_006121
KRT1
keratin 1
chr2_+_48757292 7.856 NM_001198595
NM_006873
STON1

stonin 1

chr20_-_62130390 7.845 NM_001958
EEF1A2
eukaryotic translation elongation factor 1 alpha 2
chr19_+_37407230 7.796 NM_001204835
NM_001204836
NM_001204837
NM_001204838
NM_001204839
NM_198539
ZNF568





zinc finger protein 568





chr19_+_589849 7.562 NM_001194
HCN2
hyperpolarization activated cyclic nucleotide-gated potassium channel 2
chr3_+_186648515 7.471 ST6GAL1
ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
chr4_+_191008565 7.441 NM_012147
NM_001127388
NM_001127389
NM_001164467
NM_001127386
DUX2
DUX4L6
DUX4L5
DUX4L3
DUX4L2
double homeobox 2
double homeobox 4 like 6
double homeobox 4 like 5
double homeobox 4 like 3
double homeobox 4 like 2
chr20_+_44746889 7.346 NM_001250
NM_152854
CD40

CD40 molecule, TNF receptor superfamily member 5

chr11_+_130184326 7.311 FLJ34521
uncharacterized LOC646383
chr1_-_85358851 7.267 NM_012152
LPAR3
lysophosphatidic acid receptor 3
chr17_-_27948345 7.253 NM_032854
CORO6
coronin 6
chrX_+_152760346 7.157 NM_001711
BGN
biglycan
chr20_+_45523505 7.150 EYA2
eyes absent homolog 2 (Drosophila)
chrX_-_101771641 7.097 NM_021992
TMSB15A
TMSB15B
thymosin beta 15a
thymosin beta 15B
chr6_+_13925097 7.039 NM_001165032
NM_152737
RNF182

ring finger protein 182

chr19_-_58238895 6.989 NM_024833
ZNF671
zinc finger protein 671
chr21_+_45875368 6.986 NM_030891
LRRC3
leucine rich repeat containing 3
chr4_+_190998678 6.939 NM_012147
NM_001127388
NM_001127389
NM_001164467
NM_001127386
DUX2
DUX4L6
DUX4L5
DUX4L3
DUX4L2
double homeobox 2
double homeobox 4 like 6
double homeobox 4 like 5
double homeobox 4 like 3
double homeobox 4 like 2
chr9_-_124262035 6.905 GGTA1P
glycoprotein, alpha-galactosyltransferase 1 pseudogene
chr20_+_45523523 6.858 EYA2
eyes absent homolog 2 (Drosophila)
chrX_+_151867244 6.795 NM_005363
NM_175868
MAGEA2
MAGEA6

melanoma antigen family A, 2
melanoma antigen family A, 6

chr7_+_44144002 6.779 AEBP1
AE binding protein 1
chr19_-_51504799 6.762 NM_007196
NM_144505
NM_144506
NM_144507
KLK8



kallikrein-related peptidase 8



chr19_-_51522953 6.624 NM_145888
KLK10
kallikrein-related peptidase 10
chr19_+_39279849 6.624 NM_001042507
LGALS7B
lectin, galactoside-binding, soluble, 7B
chrX_-_64196268 6.583 NM_001178033
NM_018684
ZC4H2

zinc finger, C4H2 domain containing

chrY_-_1281526 6.576 NM_001012288
NM_022148
CRLF2

cytokine receptor-like factor 2

chr19_-_18548971 6.501 NM_001170938
NM_016368
ISYNA1

inositol-3-phosphate synthase 1

chr17_+_19437140 6.489 NM_018242
SLC47A1
solute carrier family 47, member 1
chr15_-_82338348 6.473 NM_032246
MEX3B
mex-3 homolog B (C. elegans)
chr17_-_40264687 6.465 NM_024119
DHX58
DEXH (Asp-Glu-X-His) box polypeptide 58
chr19_-_51523272 6.424 NM_002776
NM_001077500
KLK10

kallikrein-related peptidase 10

chr11_-_134281725 6.420 NM_018644
NM_054025
B3GAT1

beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)

chr5_+_156887026 6.404 NM_001099287
NM_001172292
NIPAL4

NIPA-like domain containing 4

chr2_+_30454396 6.372 NM_030915
LBH
limb bud and heart development homolog (mouse)
chr7_+_44143945 6.355 NM_001129
AEBP1
AE binding protein 1
chr20_-_62103815 6.331 NM_004518
NM_172106
NM_172107
NM_172108
NM_172109
KCNQ2




potassium voltage-gated channel, KQT-like subfamily, member 2




chr4_+_191001978 6.329 NM_001177376
DUX4L4
double homeobox 4 like 4
chr19_-_10047014 6.314 NM_058164
OLFM2
olfactomedin 2
chr14_+_65007163 6.304 NM_021979
HSPA2
heat shock 70kDa protein 2
chr4_+_190995385 6.286 NM_012147
NM_001127388
NM_001127389
NM_001164467
NM_001127386
DUX2
DUX4L6
DUX4L5
DUX4L3
DUX4L2
double homeobox 2
double homeobox 4 like 6
double homeobox 4 like 5
double homeobox 4 like 3
double homeobox 4 like 2
chr2_+_238768186 6.251 NM_005855
RAMP1
receptor (G protein-coupled) activity modifying protein 1
chr1_-_151345156 6.245 NM_003944
SELENBP1
selenium binding protein 1
chr2_-_227664330 6.156 IRS1
insulin receptor substrate 1
chrX_+_75648045 6.139 NM_020932
MAGEE1
melanoma antigen family E, 1
chr2_+_73144603 6.060 NM_004097
EMX1
empty spiracles homeobox 1
chr1_+_2487803 6.038 NM_003820
TNFRSF14
tumor necrosis factor receptor superfamily, member 14
chr8_+_41685789 6.028


chrX_+_152224862 5.993 PNMA3
paraneoplastic antigen MA3
chrX_+_152224765 5.988 NM_013364
PNMA3
paraneoplastic antigen MA3
chr4_+_191005266 5.969 NM_033178
NM_012147
NM_001177376
NM_001127388
NM_001127389
NM_001164467
NM_001127386
DUX4
DUX2
DUX4L4
DUX4L6
DUX4L5
DUX4L3
DUX4L2
double homeobox 4
double homeobox 2
double homeobox 4 like 4
double homeobox 4 like 6
double homeobox 4 like 5
double homeobox 4 like 3
double homeobox 4 like 2
chr4_+_191011859 5.969 NM_033178
NM_012147
NM_001177376
NM_001127388
NM_001127389
NM_001164467
NM_001127386
DUX4
DUX2
DUX4L4
DUX4L6
DUX4L5
DUX4L3
DUX4L2
double homeobox 4
double homeobox 2
double homeobox 4 like 4
double homeobox 4 like 6
double homeobox 4 like 5
double homeobox 4 like 3
double homeobox 4 like 2
chr4_-_1107313 5.934 NM_001131034
NM_001193318
NM_194439
RNF212


ring finger protein 212


chr7_-_100493481 5.928 NM_000665
NM_015831
ACHE

acetylcholinesterase

chr2_-_163695239 5.923 NM_033272
NM_173162
KCNH7

potassium voltage-gated channel, subfamily H (eag-related), member 7

chr20_+_44098392 5.916 NM_006103
WFDC2
WAP four-disulfide core domain 2
chr11_-_75062650 5.904 NM_004041
NM_020251
ARRB1

arrestin, beta 1

chr16_+_82660573 5.892 CDH13
cadherin 13, H-cadherin (heart)
chr1_+_1950745 5.892 NM_000815
GABRD
gamma-aminobutyric acid (GABA) A receptor, delta
chrX_+_117629871 5.885 NM_144658
DOCK11
dedicator of cytokinesis 11
chr12_+_58005217 5.873 NM_182947
ARHGEF25
Rho guanine nucleotide exchange factor (GEF) 25
chr11_+_67183144 5.871 NM_001166222
NM_020811
CARNS1

carnosine synthase 1

chr4_+_190992092 5.834 NM_001177376
NM_001127388
NM_001127389
NM_001164467
DUX4L4
DUX4L6
DUX4L5
DUX4L3
double homeobox 4 like 4
double homeobox 4 like 6
double homeobox 4 like 5
double homeobox 4 like 3
chr19_-_46476556 5.823 NM_002516
NOVA2
neuro-oncological ventral antigen 2
chr2_-_220173693 5.787 NM_001199764
PTPRN
protein tyrosine phosphatase, receptor type, N
chr2_+_149633173 5.780


chr11_-_57335080 5.779 NM_004223
UBE2L6
ubiquitin-conjugating enzyme E2L 6
chr11_+_15136483 5.728 NM_001042536
INSC
inscuteable homolog (Drosophila)
chr19_-_37406918 5.707 NM_001171979
ZNF829
zinc finger protein 829
chr11_+_46403205 5.706 NM_002391
MDK
midkine (neurite growth-promoting factor 2)
chr5_-_142065586 5.706 NM_000800
FGF1
fibroblast growth factor 1 (acidic)
chr19_-_35981345 5.703 NM_001244847
NM_207392
KRTDAP

keratinocyte differentiation-associated protein

chr1_+_200993041 5.695


chr20_-_48184652 5.666 NM_000961
PTGIS
prostaglandin I2 (prostacyclin) synthase
chr17_+_6926366 5.648 NM_181844
BCL6B
B-cell CLL/lymphoma 6, member B
chr9_-_116861336 5.643 NM_138424
KIF12
kinesin family member 12
chr10_+_135493659 5.626 NM_012147
DUX2
double homeobox 2
chrX_+_152760452 5.518 BGN
biglycan
chr16_+_1203240 5.517 NM_001005407
NM_021098
CACNA1H

calcium channel, voltage-dependent, T type, alpha 1H subunit

chr11_+_46403260 5.500 MDK
midkine (neurite growth-promoting factor 2)
chr15_-_48470319 5.483 MYEF2
myelin expression factor 2
chr20_-_22564893 5.430 FOXA2
forkhead box A2
chr19_+_50706868 5.419 NM_001077186
NM_001145809
NM_024729
MYH14


myosin, heavy chain 14, non-muscle


chr10_+_135483677 5.389 NM_033178
NM_012147
NM_001127387
NM_001127388
NM_001127389
NM_001164467
NM_001127386
DUX4
DUX2
DUX4L7
DUX4L6
DUX4L5
DUX4L3
DUX4L2
double homeobox 4
double homeobox 2
double homeobox 4 like 7
double homeobox 4 like 6
double homeobox 4 like 5
double homeobox 4 like 3
double homeobox 4 like 2
chrX_-_17879355 5.372 NM_001172732
NM_001172739
NM_001172743
NM_021785
RAI2



retinoic acid induced 2



chr5_-_134914447 5.368 CXCL14
chemokine (C-X-C motif) ligand 14
chr11_+_46403279 5.366 MDK
midkine (neurite growth-promoting factor 2)
chr10_+_135480367 5.321 NM_033178
NM_012147
NM_001127387
NM_001127388
NM_001127389
NM_001164467
NM_001127386
DUX4
DUX2
DUX4L7
DUX4L6
DUX4L5
DUX4L3
DUX4L2
double homeobox 4
double homeobox 2
double homeobox 4 like 7
double homeobox 4 like 6
double homeobox 4 like 5
double homeobox 4 like 3
double homeobox 4 like 2
chr19_+_15218141 5.306 NM_033025
SYDE1
synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
chr21_+_47063573 5.301 PCBP3
poly(rC) binding protein 3
chr2_+_237478379 5.301 NM_020311
CXCR7
chemokine (C-X-C motif) receptor 7
chr17_-_48207113 5.288 NM_174920
SAMD14
sterile alpha motif domain containing 14
chr3_-_114866090 5.249 NM_015642
ZBTB20
zinc finger and BTB domain containing 20
chr2_-_128433330 5.237 LIMS2
LIM and senescent cell antigen-like domains 2
chr1_-_99470177 5.210 NM_001010861
NM_001037317
LPPR5

lipid phosphate phosphatase-related protein type 5

chrX_+_153813417 5.208 NM_001327
NM_139250
CTAG1B
CTAG1A
cancer/testis antigen 1B
cancer/testis antigen 1A
chr7_-_4998744 5.187 NM_001100600
NM_198403
MMD2

monocyte to macrophage differentiation-associated 2

chr19_-_17137449 5.168 NM_015692
CPAMD8
C3 and PZP-like, alpha-2-macroglobulin domain containing 8
chr12_-_42983412 5.160 NM_153026
PRICKLE1
prickle homolog 1 (Drosophila)
chr6_-_89827605 5.156 NM_080743
SRSF12
serine/arginine-rich splicing factor 12
chr22_+_51039178 5.153 MAPK8IP2
mitogen-activated protein kinase 8 interacting protein 2
chr13_-_49107250 5.148 NM_001268
RCBTB2
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
chr19_-_12146503 5.131 NM_001080411
ZNF433
zinc finger protein 433
chr3_-_10547267 5.131 NM_001001331
NM_001683
ATP2B2

ATPase, Ca++ transporting, plasma membrane 2

chr19_-_47975074 5.128 SLC8A2
solute carrier family 8 (sodium/calcium exchanger), member 2
chr4_+_190988866 5.121 NM_012147
DUX2
double homeobox 2
chr17_+_5973640 5.120 NM_015253
WSCD1
WSC domain containing 1
chr1_+_21835915 5.025 ALPL
alkaline phosphatase, liver/bone/kidney
chr13_-_20806533 4.996 NM_001110219
NM_001110220
NM_001110221
GJB6


gap junction protein, beta 6, 30kDa


chr5_-_115910406 4.963 NM_020796
SEMA6A
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr12_+_70759974 4.914 NM_014505
KCNMB4
potassium large conductance calcium-activated channel, subfamily M, beta member 4
chr11_+_66790189 4.893 NM_001177880
SYT12
synaptotagmin XII
chr22_+_51039100 4.882 NM_012324
MAPK8IP2
mitogen-activated protein kinase 8 interacting protein 2
chr16_-_28303366 4.878


chr19_+_55999859 4.870 NM_001144950
NM_001195267
SSC5D

scavenger receptor cysteine rich domain containing (5 domains)

chr12_+_132312917 4.852 NM_016155
MMP17
matrix metallopeptidase 17 (membrane-inserted)
chr15_-_45480160 4.851 SHF
Src homology 2 domain containing F
chr9_-_116861506 4.842 KIF12
kinesin family member 12
chr1_+_210111575 4.841 SYT14
synaptotagmin XIV
chr19_+_55999921 4.840 SSC5D
scavenger receptor cysteine rich domain containing (5 domains)
chr11_-_1016736 4.838 MUC6
mucin 6, oligomeric mucus/gel-forming
chr10_+_135490278 4.810 NM_001127388
NM_001127389
NM_001164467
NM_001127386
DUX4L6
DUX4L5
DUX4L3
DUX4L2
double homeobox 4 like 6
double homeobox 4 like 5
double homeobox 4 like 3
double homeobox 4 like 2
chr20_-_22565050 4.807 NM_021784
FOXA2
forkhead box A2
chr5_+_52776263 4.788 NM_006350
NM_013409
FST

follistatin

chr8_-_82395401 4.770 NM_001442
FABP4
fatty acid binding protein 4, adipocyte
chr11_-_17498419 4.741 NM_000352
ABCC8
ATP-binding cassette, sub-family C (CFTR/MRP), member 8
chr16_+_1203737 4.730 CACNA1H
calcium channel, voltage-dependent, T type, alpha 1H subunit
chr19_-_409169 4.726 NM_001136263
C2CD4C
C2 calcium-dependent domain containing 4C
chr12_-_54694717 4.710 NM_001136023
NFE2
nuclear factor (erythroid-derived 2), 45kDa
chr19_-_18717577 4.709 CRLF1
cytokine receptor-like factor 1
chr20_-_9819406 4.706 NM_020341
NM_177990
PAK7

p21 protein (Cdc42/Rac)-activated kinase 7

chr22_-_30662787 4.705 NM_020530
OSM
oncostatin M
chr3_+_129612702 4.665 LOC100507032
uncharacterized LOC100507032
chr19_+_33210678 4.659 NM_001110822
TDRD12
tudor domain containing 12
chr19_-_18717631 4.657 NM_004750
CRLF1
cytokine receptor-like factor 1
chr6_-_31560497 4.642 NM_001145466
NM_001145467
NM_147130
NCR3


natural cytotoxicity triggering receptor 3


chr16_-_19896105 4.641 NM_016235
GPRC5B
G protein-coupled receptor, family C, group 5, member B
chr11_-_113345841 4.611 NM_000795
NM_016574
DRD2

dopamine receptor D2

chr1_-_1535446 4.607 NM_001242659
LOC643988
uncharacterized LOC643988
chr4_+_184827805 4.604 STOX2
storkhead box 2
chr15_+_68871285 4.573 NM_006091
CORO2B
coronin, actin binding protein, 2B
chr22_-_44258210 4.562 NM_014351
SULT4A1
sulfotransferase family 4A, member 1
chr4_+_184827882 4.552


chr5_+_52776408 4.550 FST
follistatin
chr7_-_150498362 4.549 NM_014020
TMEM176B
transmembrane protein 176B
chrX_-_83442906 4.548 NM_014496
RPS6KA6
ribosomal protein S6 kinase, 90kDa, polypeptide 6
chr7_+_75932992 4.539 HSPB1
heat shock 27kDa protein 1
chr19_+_3880617 4.518 NM_033064
ATCAY
ataxia, cerebellar, Cayman type
chr11_+_57365026 4.502 NM_000062
SERPING1
serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
chr11_-_76381787 4.501 NM_001128922
LRRC32
leucine rich repeat containing 32
chr1_+_210111537 4.471 NM_001146261
NM_001146262
NM_001146264
NM_153262
SYT14



synaptotagmin XIV




Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
1.74 5.69e-25 GO:0048856 anatomical structure development
1.79 6.88e-25 GO:0048731 system development
2.18 1.38e-24 GO:0007399 nervous system development
1.67 5.44e-23 GO:0007275 multicellular organismal development
1.62 5.91e-23 GO:0032502 developmental process
1.88 2.58e-20 GO:0030154 cell differentiation
1.46 2.88e-20 GO:0032501 multicellular organismal process
1.85 1.12e-19 GO:0048869 cellular developmental process
1.86 1.64e-17 GO:0048513 organ development
2.32 2.46e-17 GO:0022008 neurogenesis
1.98 3.19e-17 GO:0009653 anatomical structure morphogenesis
2.54 3.85e-17 GO:0030182 neuron differentiation
2.31 4.71e-16 GO:0048699 generation of neurons
2.69 1.92e-14 GO:0007417 central nervous system development
2.14 3.37e-13 GO:0048468 cell development
2.83 1.52e-11 GO:0007420 brain development
2.37 2.17e-11 GO:0009887 organ morphogenesis
2.52 3.16e-11 GO:0019226 transmission of nerve impulse
2.52 3.16e-11 GO:0035637 multicellular organismal signaling
2.16 9.78e-11 GO:0007267 cell-cell signaling
2.58 1.34e-10 GO:0007268 synaptic transmission
1.83 4.13e-10 GO:0051239 regulation of multicellular organismal process
2.31 7.24e-10 GO:0048666 neuron development
1.94 1.05e-09 GO:0007154 cell communication
1.97 2.71e-09 GO:0050793 regulation of developmental process
2.36 4.04e-09 GO:0000904 cell morphogenesis involved in differentiation
2.17 3.91e-08 GO:0000902 cell morphogenesis
2.11 1.01e-07 GO:0032989 cellular component morphogenesis
2.33 2.33e-07 GO:0048667 cell morphogenesis involved in neuron differentiation
2.23 3.29e-07 GO:0031175 neuron projection development
2.29 5.00e-07 GO:0048812 neuron projection morphogenesis
1.89 5.31e-07 GO:0009888 tissue development
2.22 6.25e-07 GO:0030001 metal ion transport
1.95 6.42e-07 GO:2000026 regulation of multicellular organismal development
3.16 7.31e-07 GO:0030900 forebrain development
2.00 9.48e-07 GO:0045595 regulation of cell differentiation
2.27 2.63e-06 GO:0007409 axonogenesis
1.82 3.44e-06 GO:0006811 ion transport
2.10 1.12e-05 GO:0048858 cell projection morphogenesis
3.06 1.59e-05 GO:0006813 potassium ion transport
2.08 1.61e-05 GO:0032990 cell part morphogenesis
1.85 2.20e-05 GO:0007155 cell adhesion
1.85 2.20e-05 GO:0022610 biological adhesion
1.93 3.01e-05 GO:0030030 cell projection organization
3.08 3.98e-05 GO:0045165 cell fate commitment
1.87 5.63e-05 GO:0009790 embryo development
2.30 9.58e-05 GO:0051093 negative regulation of developmental process
1.18 9.69e-05 GO:0065007 biological regulation
1.94 1.17e-04 GO:0006812 cation transport
2.48 3.36e-04 GO:0003002 regionalization
5.06 5.85e-04 GO:0021987 cerebral cortex development
2.19 6.31e-04 GO:0044057 regulation of system process
2.20 1.00e-03 GO:0001501 skeletal system development
2.14 1.24e-03 GO:0007389 pattern specification process
4.50 1.27e-03 GO:0021510 spinal cord development
2.82 1.35e-03 GO:0001655 urogenital system development
1.78 1.39e-03 GO:0010628 positive regulation of gene expression
1.46 1.50e-03 GO:0003008 system process
2.07 2.13e-03 GO:0048598 embryonic morphogenesis
2.16 2.28e-03 GO:0060284 regulation of cell development
2.23 2.87e-03 GO:0051960 regulation of nervous system development
3.06 3.16e-03 GO:0072001 renal system development
2.11 3.17e-03 GO:0007411 axon guidance
4.48 3.18e-03 GO:0048663 neuron fate commitment
3.48 3.42e-03 GO:0021953 central nervous system neuron differentiation
4.38 4.32e-03 GO:0007422 peripheral nervous system development
1.37 4.54e-03 GO:0042221 response to chemical stimulus
1.60 4.76e-03 GO:0009605 response to external stimulus
2.08 6.33e-03 GO:0015672 monovalent inorganic cation transport
1.76 7.85e-03 GO:0045893 positive regulation of transcription, DNA-dependent
3.57 8.12e-03 GO:0009953 dorsal/ventral pattern formation
3.13 1.05e-02 GO:0021537 telencephalon development
1.86 1.07e-02 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
2.41 1.11e-02 GO:0048732 gland development
2.37 1.13e-02 GO:0045664 regulation of neuron differentiation
2.19 1.16e-02 GO:0045596 negative regulation of cell differentiation
1.62 1.20e-02 GO:0040011 locomotion
2.99 1.33e-02 GO:0021700 developmental maturation
2.25 1.39e-02 GO:0048568 embryonic organ development
3.77 1.49e-02 GO:0021543 pallium development
2.21 1.66e-02 GO:0050767 regulation of neurogenesis
1.36 1.72e-02 GO:0048523 negative regulation of cellular process
2.08 1.77e-02 GO:0048729 tissue morphogenesis
3.03 1.78e-02 GO:0006816 calcium ion transport
1.95 1.83e-02 GO:0060429 epithelium development
4.84 1.92e-02 GO:0015914 phospholipid transport
2.90 2.18e-02 GO:0001822 kidney development
5.22 2.34e-02 GO:0048709 oligodendrocyte differentiation
3.47 2.41e-02 GO:0030902 hindbrain development
1.71 2.43e-02 GO:0048878 chemical homeostasis
1.55 2.51e-02 GO:0032879 regulation of localization
5.76 2.56e-02 GO:0022029 telencephalon cell migration
3.04 2.84e-02 GO:0001505 regulation of neurotransmitter levels
1.64 3.06e-02 GO:0010557 positive regulation of macromolecule biosynthetic process
2.03 3.28e-02 GO:0022603 regulation of anatomical structure morphogenesis
6.26 3.91e-02 GO:0060042 retina morphogenesis in camera-type eye
5.51 3.95e-02 GO:0021885 forebrain cell migration
2.07 4.30e-02 GO:0035295 tube development
2.46 4.61e-02 GO:0048562 embryonic organ morphogenesis
4.12 4.82e-02 GO:0007613 memory

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
1.67 4.62e-14 GO:0044459 plasma membrane part
1.83 6.02e-11 GO:0005887 integral to plasma membrane
1.82 6.42e-11 GO:0031226 intrinsic to plasma membrane
1.60 1.33e-10 GO:0005576 extracellular region
2.58 2.96e-10 GO:0031012 extracellular matrix
2.72 4.88e-10 GO:0005578 proteinaceous extracellular matrix
1.88 4.90e-10 GO:0044421 extracellular region part
1.37 9.76e-10 GO:0005886 plasma membrane
1.36 3.01e-09 GO:0071944 cell periphery
2.84 1.91e-07 GO:0034702 ion channel complex
3.34 3.37e-07 GO:0034703 cation channel complex
2.14 7.45e-06 GO:0045202 synapse
1.24 1.63e-05 GO:0031224 intrinsic to membrane
1.86 4.10e-05 GO:0030054 cell junction
2.25 6.23e-05 GO:0044456 synapse part
1.22 1.52e-04 GO:0016021 integral to membrane
5.09 1.86e-04 GO:0005581 collagen
1.68 2.77e-04 GO:0005615 extracellular space
3.24 7.61e-04 GO:0008076 voltage-gated potassium channel complex
3.24 7.61e-04 GO:0034705 potassium channel complex
1.18 8.68e-04 GO:0044425 membrane part
1.91 1.68e-03 GO:0043005 neuron projection
1.14 4.71e-03 GO:0016020 membrane
1.85 8.95e-03 GO:0009986 cell surface
3.76 1.70e-02 GO:0030672 synaptic vesicle membrane
5.37 1.90e-02 GO:0005891 voltage-gated calcium channel complex

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
2.30 2.45e-13 GO:0043565 sequence-specific DNA binding
2.55 1.69e-10 GO:0022838 substrate-specific channel activity
1.93 1.99e-10 GO:0001071 nucleic acid binding transcription factor activity
1.93 1.99e-10 GO:0003700 sequence-specific DNA binding transcription factor activity
2.55 2.36e-10 GO:0005216 ion channel activity
2.47 7.71e-10 GO:0015267 channel activity
2.47 8.72e-10 GO:0022803 passive transmembrane transporter activity
2.83 2.24e-09 GO:0005261 cation channel activity
2.67 4.20e-09 GO:0022836 gated channel activity
3.57 6.39e-09 GO:0022843 voltage-gated cation channel activity
2.00 1.00e-08 GO:0015075 ion transmembrane transporter activity
3.09 3.56e-08 GO:0005244 voltage-gated ion channel activity
3.09 3.56e-08 GO:0022832 voltage-gated channel activity
1.84 4.68e-08 GO:0022857 transmembrane transporter activity
1.72 5.51e-08 GO:0005215 transporter activity
1.83 3.55e-07 GO:0022891 substrate-specific transmembrane transporter activity
2.05 5.30e-07 GO:0008324 cation transmembrane transporter activity
1.69 8.44e-06 GO:0022892 substrate-specific transporter activity
1.67 1.99e-05 GO:0030528 transcription regulator activity
3.13 2.77e-05 GO:0005267 potassium channel activity
3.52 3.05e-04 GO:0005201 extracellular matrix structural constituent
2.47 4.76e-04 GO:0010843 promoter binding
3.16 6.16e-04 GO:0005249 voltage-gated potassium channel activity
2.37 1.23e-03 GO:0000975 regulatory region DNA binding
2.37 1.23e-03 GO:0001067 regulatory region nucleic acid binding
2.37 1.23e-03 GO:0044212 transcription regulatory region DNA binding
3.11 1.27e-02 GO:0005262 calcium channel activity
4.88 2.62e-02 GO:0005245 voltage-gated calcium channel activity
2.85 4.12e-02 GO:0003705 sequence-specific enhancer binding RNA polymerase II transcription factor activity