Motif ID: RORA.p2

Z-value: 0.562


Transcription factors associated with RORA.p2:

Gene SymbolEntrez IDGene Name
RORA 6095 RAR-related orphan receptor A

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
RORAhg19_v1_chr15_-_60884615_60884744-0.431.2e-04Click!


Activity profile for motif RORA.p2.

activity profile for motif RORA.p2


Sorted Z-values histogram for motif RORA.p2

Sorted Z-values for motif RORA.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of RORA.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr18_-_56296188 3.488 NM_052947
ALPK2
alpha-kinase 2
chr2_-_31030271 3.210 NM_144575
CAPN13
calpain 13
chr19_-_55580896 2.312 NM_138412
RDH13
retinol dehydrogenase 13 (all-trans/9-cis)
chr7_+_101928390 2.284 NM_020979
SH2B2
SH2B adaptor protein 2
chr7_+_101928417 2.270 SH2B2
SH2B adaptor protein 2
chr11_+_13299329 2.028 ARNTL
aryl hydrocarbon receptor nuclear translocator-like
chr11_+_13299349 1.947 ARNTL
aryl hydrocarbon receptor nuclear translocator-like
chr11_+_13299372 1.918 ARNTL
aryl hydrocarbon receptor nuclear translocator-like
chr1_-_41487386 1.896 NM_001168247
NM_144990
SLFNL1

schlafen-like 1

chr11_+_13299376 1.882 ARNTL
aryl hydrocarbon receptor nuclear translocator-like
chr11_+_13299260 1.805 NM_001030272
NM_001030273
NM_001178
ARNTL


aryl hydrocarbon receptor nuclear translocator-like


chr6_+_43738757 1.708 VEGFA
vascular endothelial growth factor A
chrX_-_71527000 1.650 NM_001144886
CITED1
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1
chr6_+_43738394 1.599 VEGFA
vascular endothelial growth factor A
chr11_+_13299391 1.546 ARNTL
aryl hydrocarbon receptor nuclear translocator-like
chr6_+_43737937 1.539 NM_001025366
NM_001025367
NM_001025368
NM_001025369
NM_001025370
NM_001033756
NM_001171622
NM_001171623
NM_001171624
NM_001171625
NM_001171626
NM_001171627
NM_001171628
NM_001171629
NM_001171630
NM_001204384
NM_001204385
NM_003376
VEGFA

















vascular endothelial growth factor A

















chr2_+_29038862 1.400 NM_001008779
SPDYA
speedy homolog A (Xenopus laevis)
chr5_-_134914968 1.243 NM_004887
CXCL14
chemokine (C-X-C motif) ligand 14
chr7_-_128415843 1.191 NM_001708
OPN1SW
opsin 1 (cone pigments), short-wave-sensitive
chr4_+_110749149 1.181 NM_006583
RRH
retinal pigment epithelium-derived rhodopsin homolog
chr15_+_40509628 1.155 NM_001128628
NM_001128629
PAK6

p21 protein (Cdc42/Rac)-activated kinase 6

chr17_-_38859976 1.115 NM_019016
KRT24
keratin 24
chr5_+_38258660 0.987 EGFLAM
EGF-like, fibronectin type III and laminin G domains
chr16_+_27325269 0.943 IL4R
interleukin 4 receptor
chr5_+_38258510 0.934 NM_001205301
NM_152403
EGFLAM

EGF-like, fibronectin type III and laminin G domains

chr10_+_101542554 0.929 ABCC2
ATP-binding cassette, sub-family C (CFTR/MRP), member 2
chr7_+_120969089 0.921 NM_057168
WNT16
wingless-type MMTV integration site family, member 16
chr11_-_47615902 0.862 NM_031909
C1QTNF4
C1q and tumor necrosis factor related protein 4
chr1_+_67632168 0.812 NM_144701
IL23R
interleukin 23 receptor
chr2_+_219472631 0.799 PLCD4
phospholipase C, delta 4
chr2_+_171034654 0.776 NM_001083615
NM_001171642
NM_138995
MYO3B


myosin IIIB


chr1_+_40862471 0.770 NM_001198980
SMAP2
small ArfGAP2
chr3_+_158991090 0.758 SCHIP1
schwannomin interacting protein 1
chr18_+_32073343 0.712 DTNA
dystrobrevin, alpha
chr4_+_155484131 0.669 NM_001184741
NM_005141
FGB

fibrinogen beta chain

chr4_+_156824846 0.637 NM_005651
TDO2
tryptophan 2,3-dioxygenase
chr12_+_93963597 0.630 NM_003877
SOCS2
suppressor of cytokine signaling 2
chr11_-_67271839 0.629 PITPNM1
phosphatidylinositol transfer protein, membrane-associated 1
chr3_+_151531860 0.625 NM_001086
AADAC
arylacetamide deacetylase (esterase)
chr1_-_47695442 0.608 NM_003189
TAL1
T-cell acute lymphocytic leukemia 1
chr12_-_48119224 0.587 NM_001172439
NM_001172440
NM_006025
ENDOU


endonuclease, polyU-specific


chr18_+_32073245 0.568 NM_001198945
NM_001392
NM_032975
NM_032979
DTNA



dystrobrevin, alpha



chr6_+_43738177 0.564 VEGFA
vascular endothelial growth factor A
chr3_+_184038050 0.560 NM_004953
EIF4G1
eukaryotic translation initiation factor 4 gamma, 1
chr10_-_21435487 0.558 NM_001010896
NM_001177483
C10orf113

chromosome 10 open reading frame 113

chr22_+_21821458 0.550 NM_001207052
TMEM191C
transmembrane protein 191C
chr8_-_134072404 0.542 NM_006748
SLA
Src-like-adaptor
chr17_+_40996596 0.541 NM_001158
NM_009590
AOC2

amine oxidase, copper containing 2 (retina-specific)

chr6_-_136847743 0.537 NM_001198614
NM_001198618
NM_001198619
MAP7


microtubule-associated protein 7


chr12_+_55248298 0.529 NM_058173
MUCL1
mucin-like 1
chr2_+_219472487 0.524 NM_032726
PLCD4
phospholipase C, delta 4
chr1_-_203155867 0.519 CHI3L1
chitinase 3-like 1 (cartilage glycoprotein-39)
chr12_-_42538432 0.514 NM_001099650
NM_173601
GXYLT1

glucoside xylosyltransferase 1

chr19_+_1776117 0.511


chr10_-_52645384 0.509 A1CF
APOBEC1 complementation factor
chr6_+_15245702 0.505 JARID2
jumonji, AT rich interactive domain 2
chr1_-_211751719 0.505 SLC30A1
solute carrier family 30 (zinc transporter), member 1
chr5_-_133561805 0.504 NM_002715
PPP2CA
protein phosphatase 2, catalytic subunit, alpha isozyme
chr3_-_50360109 0.495 NM_003773
NM_033158
HYAL2

hyaluronoglucosaminidase 2

chr16_-_21831730 0.492 RRN3P1
RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 1
chr3_-_24536452 0.478 THRB
thyroid hormone receptor, beta
chr10_-_52645430 0.472 NM_001198818
NM_001198819
NM_001198820
NM_014576
NM_138932
NM_138933
A1CF





APOBEC1 complementation factor





chr16_-_12009918 0.455 GSPT1
G1 to S phase transition 1
chr12_+_60083125 0.448 NM_004731
SLC16A7
solute carrier family 16, member 7 (monocarboxylic acid transporter 2)
chr1_-_203155910 0.448 NM_001276
CHI3L1
chitinase 3-like 1 (cartilage glycoprotein-39)
chr2_-_16081703 0.441 MYCNOS
MYCN opposite strand/antisense RNA (non-protein coding)
chr17_+_71161110 0.430 NM_001050
SSTR2
somatostatin receptor 2
chr19_-_7698569 0.429 NM_174895
PCP2
Purkinje cell protein 2
chr17_-_2304217 0.412 NM_020310
MNT
MAX binding protein
chr9_+_125281418 0.410 NM_001004452
OR1J4
olfactory receptor, family 1, subfamily J, member 4
chr1_-_85155885 0.401 NM_001166295
NM_001166417
NM_001166293
NM_001166294
NM_014021
SSX2IP




synovial sarcoma, X breakpoint 2 interacting protein




chr16_-_15188089 0.394 NM_018427
RRN3
RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae)
chr1_+_152483319 0.391 NM_178438
LCE5A
late cornified envelope 5A
chr1_-_33813261 0.372


chr18_-_56985693 0.367 NM_181654
CPLX4
complexin 4
chr1_+_17846818 0.359 ARHGEF10L
Rho guanine nucleotide exchange factor (GEF) 10-like
chr17_-_34308455 0.359 NM_004590
CCL16
chemokine (C-C motif) ligand 16
chr11_-_70672861 0.344 SHANK2
SH3 and multiple ankyrin repeat domains 2
chr20_-_1309782 0.334 SDCBP2
syndecan binding protein (syntenin) 2
chr5_+_38258856 0.333


chr14_-_70655589 0.331 NM_033262
NM_058240
NM_182932
NM_183002
SLC8A3



solute carrier family 8 (sodium/calcium exchanger), member 3



chr1_-_204165542 0.325 NM_002256
KISS1
KiSS-1 metastasis-suppressor
chr15_-_52263947 0.325 NM_138792
LEO1
Leo1, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
chrX_-_108725284 0.322 NM_001522
GUCY2F
guanylate cyclase 2F, retinal
chrX_-_62648209 0.313 LOC92249
uncharacterized LOC92249
chr16_+_1832928 0.307 NM_012225
NUBP2
nucleotide binding protein 2
chr12_+_121132677 0.301


chr17_+_26369935 0.295 NLK
nemo-like kinase
chr19_-_50464306 0.288 NM_001135163
NM_052884
SIGLEC11

sialic acid binding Ig-like lectin 11

chr8_-_82395401 0.281 NM_001442
FABP4
fatty acid binding protein 4, adipocyte
chr9_+_120466453 0.279 NM_138554
TLR4
toll-like receptor 4
chr3_-_149375584 0.264 NM_001168280
NM_015472
WWTR1

WW domain containing transcription regulator 1

chr11_-_119599253 0.259 NM_002855
NM_203285
NM_203286
PVRL1


poliovirus receptor-related 1 (herpesvirus entry mediator C)


chr8_-_144654921 0.259 NM_001100878
C8orf73
chromosome 8 open reading frame 73
chr3_+_9944295 0.258 NM_153483
IL17RE
interleukin 17 receptor E
chr6_+_158734476 0.257 TULP4
tubby like protein 4
chr11_+_33350076 0.257 HIPK3
homeodomain interacting protein kinase 3
chr14_-_24804243 0.250 NM_001198568
NM_001198592
NM_139247
ADCY4


adenylate cyclase 4


chr19_+_50321503 0.247 NM_030973
MED25
mediator complex subunit 25
chr18_-_3874688 0.246 NM_001242762
NM_001242763
DLGAP1

discs, large (Drosophila) homolog-associated protein 1

chr1_-_211751953 0.242 SLC30A1
solute carrier family 30 (zinc transporter), member 1
chr12_+_105153258 0.237 CHST11
carbohydrate (chondroitin 4) sulfotransferase 11
chr12_-_57351381 0.236 NM_003708
RDH16
retinol dehydrogenase 16 (all-trans)
chr17_+_26369617 0.232 NM_016231
NLK
nemo-like kinase
chr1_-_203155827 0.231 CHI3L1
chitinase 3-like 1 (cartilage glycoprotein-39)
chr9_+_74920329 0.230


chr18_+_55816546 0.230 NM_001144965
NM_001144968
NM_001144969
NM_001144971
NEDD4L



neural precursor cell expressed, developmentally down-regulated 4-like



chr3_-_24536176 0.230 NM_000461
NM_001128176
NM_001128177
NM_001252634
THRB



thyroid hormone receptor, beta



chr2_+_219472618 0.227 PLCD4
phospholipase C, delta 4
chr19_+_42381189 0.223 NM_001783
NM_021601
CD79A

CD79a molecule, immunoglobulin-associated alpha

chr4_+_140222620 0.223 NAA15
N(alpha)-acetyltransferase 15, NatA auxiliary subunit
chr6_-_30128688 0.221 NM_006778
NM_052828
TRIM10

tripartite motif containing 10

chr2_+_233243243 0.218 NM_001632
ALPP
alkaline phosphatase, placental
chr7_+_129007942 0.214 NM_001130723
AHCYL2
adenosylhomocysteinase-like 2
chr12_+_56414688 0.211 NM_022465
IKZF4
IKAROS family zinc finger 4 (Eos)
chr7_+_129008044 0.206 AHCYL2
adenosylhomocysteinase-like 2
chr11_-_2159784 0.202 IGF2
insulin-like growth factor 2 (somatomedin A)
chr9_-_139292888 0.195 NM_003086
SNAPC4
small nuclear RNA activating complex, polypeptide 4, 190kDa
chr1_+_158149736 0.194 NM_001766
CD1D
CD1d molecule
chr1_-_103496768 0.194 COL11A1
collagen, type XI, alpha 1
chr16_+_1833003 0.192


chr6_+_4836331 0.186 NM_001143970
CDYL
chromodomain protein, Y-like
chr22_-_33402648 0.182 NM_003490
NM_133633
SYN3

synapsin III

chr12_+_50479033 0.179 SMARCD1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
chr10_+_51549552 0.174 NM_002443
NM_138634
MSMB

microseminoprotein, beta-

chr1_+_20396652 0.173 NM_000929
PLA2G5
phospholipase A2, group V
chr22_+_21771661 0.170 NM_015094
HIC2
hypermethylated in cancer 2
chr9_-_139342563 0.170 SEC16A
SEC16 homolog A (S. cerevisiae)
chr1_+_109255555 0.165 NM_001144937
FNDC7
fibronectin type III domain containing 7
chr2_+_27301434 0.165 NM_007046
EMILIN1
elastin microfibril interfacer 1
chr11_-_2159472 0.157 IGF2
insulin-like growth factor 2 (somatomedin A)
chr6_-_37225894 0.152 NM_001162900
TMEM217
transmembrane protein 217
chr11_-_124806302 0.151 NM_152722
HEPACAM
hepatic and glial cell adhesion molecule
chr1_+_111833473 0.149 NM_021797
NM_201653
CHIA

chitinase, acidic

chr7_+_134916730 0.148 NM_182489
STRA8
stimulated by retinoic acid gene 8 homolog (mouse)
chr1_-_156786500 0.141 NM_001161441
NM_001161442
NM_001161444
NM_003975
SH2D2A



SH2 domain containing 2A



chr6_-_30181197 0.138 NM_001242783
NM_003449
TRIM26

tripartite motif containing 26

chr4_-_120243257 0.138 NM_000134
FABP2
fatty acid binding protein 2, intestinal
chr19_-_16250695 0.133


chr3_+_44596596 0.131 NM_018651
NM_025169
ZNF167

zinc finger protein 167

chr3_-_184095927 0.130 NM_000460
NM_001177597
NM_001177598
THPO


thrombopoietin


chr13_-_52733995 0.128 NM_001146099
NM_002498
NEK3

NIMA (never in mitosis gene a)-related kinase 3

chr16_+_24266873 0.126 NM_006539
CACNG3
calcium channel, voltage-dependent, gamma subunit 3
chr11_-_2160199 0.126 NM_000612
IGF2
insulin-like growth factor 2 (somatomedin A)
chr2_+_121554866 0.123 NM_005270
GLI2
GLI family zinc finger 2
chr10_+_96953956 0.121 NM_207321
C10orf129
chromosome 10 open reading frame 129
chr15_-_65670325 0.119 NM_004884
IGDCC3
immunoglobulin superfamily, DCC subclass, member 3
chrX_-_23925947 0.117 NM_024122
APOO
apolipoprotein O
chr7_+_20655244 0.116 NM_001163941
ABCB5
ATP-binding cassette, sub-family B (MDR/TAP), member 5
chr3_+_132318980 0.116 NM_178445
CCRL1
chemokine (C-C motif) receptor-like 1
chr4_+_144106052 0.111 NM_032557
USP38
ubiquitin specific peptidase 38
chr1_-_247697140 0.110 NM_198074
OR2C3
olfactory receptor, family 2, subfamily C, member 3
chr8_-_6420454 0.107 NM_001118887
NM_001118888
NM_001147
ANGPT2


angiopoietin 2


chr6_-_24383519 0.106 NM_001195610
DCDC2
doublecortin domain containing 2
chr6_+_143929316 0.105 NM_001100166
NM_014721
PHACTR2

phosphatase and actin regulator 2

chr3_-_122233781 0.104 NM_002264
KPNA1
karyopherin alpha 1 (importin alpha 5)
chr19_+_58361219 0.101 ZNF587
zinc finger protein 587
chr12_+_113376301 0.100 OAS3
2'-5'-oligoadenylate synthetase 3, 100kDa
chr6_-_64029847 0.099 NM_001143940
NM_016571
LGSN

lengsin, lens protein with glutamine synthetase domain

chr11_-_72380107 0.098 NM_001146209
PDE2A
phosphodiesterase 2A, cGMP-stimulated
chr10_+_91137812 0.097 NM_001010987
IFIT1B
interferon-induced protein with tetratricopeptide repeats 1B
chr1_+_33116748 0.096 NM_001135255
NM_005610
NM_001135256
RBBP4


retinoblastoma binding protein 4


chr7_+_112063131 0.096 NM_001007245
NM_001197080
IFRD1

interferon-related developmental regulator 1

chr12_+_113376001 0.095 OAS3
2'-5'-oligoadenylate synthetase 3, 100kDa
chrX_+_12924738 0.091 NM_138636
TLR8
toll-like receptor 8
chr8_+_120220554 0.091 NM_052886
MAL2
mal, T-cell differentiation protein 2 (gene/pseudogene)
chr15_-_31393906 0.091 NM_001252024
NM_001252030
NM_002420
TRPM1


transient receptor potential cation channel, subfamily M, member 1


chr13_-_103719195 0.090 NM_000452
SLC10A2
solute carrier family 10 (sodium/bile acid cotransporter family), member 2
chr11_+_131780537 0.090 NM_001144058
NM_001144059
NM_016522
NTM


neurotrimin


chrX_-_2882288 0.088 NM_000047
ARSE
arylsulfatase E (chondrodysplasia punctata 1)
chr2_-_37193609 0.087 NM_003162
STRN
striatin, calmodulin binding protein
chr3_+_48413708 0.086 NM_001159927
NM_001159929
NM_207102
FBXW12


F-box and WD repeat domain containing 12


chrX_-_57147850 0.085 NM_001006681
NM_001006682
NM_001006683
SPIN2B


spindlin family, member 2B


chr10_+_114043413 0.085 NM_058222
TECTB
tectorin beta
chr1_-_211752052 0.084 NM_021194
SLC30A1
solute carrier family 30 (zinc transporter), member 1
chrX_+_65235279 0.080


chr17_-_26697358 0.079 NM_000638
VTN
vitronectin
chrX_-_32173585 0.079 NM_004013
NM_004020
NM_004021
NM_004022
NM_004023
DMD




dystrophin




chrM_+_5769 0.079


chr3_-_122233764 0.078 KPNA1
karyopherin alpha 1 (importin alpha 5)
chr16_+_67207755 0.078 NM_003946
NM_001185057
NOL3

nucleolar protein 3 (apoptosis repressor with CARD domain)

chr1_-_177939347 0.077 SEC16B
SEC16 homolog B (S. cerevisiae)
chr1_-_177134042 0.076 ASTN1
astrotactin 1
chr14_+_74815194 0.076 VRTN
vertebrae development homolog (pig)
chr1_+_157963062 0.076 NM_018240
KIRREL
kin of IRRE like (Drosophila)
chr14_+_92788924 0.074 NM_153648
SLC24A4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr17_-_48266313 0.073 COL1A1
collagen, type I, alpha 1
chr10_-_72362513 0.071 NM_001083116
NM_005041
PRF1

perforin 1 (pore forming protein)

chr14_+_94492747 0.071 OTUB2
OTU domain, ubiquitin aldehyde binding 2
chr17_+_7533403 0.070 SHBG
sex hormone-binding globulin
chrX_-_102531673 0.069 NM_001012979
TCEAL5
transcription elongation factor A (SII)-like 5
chr1_-_161147757 0.069 NM_001199873
NM_001199874
NM_003779
B4GALT3


UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3


chr19_+_8953268 0.066 NM_145208
MBD3L1
methyl-CpG binding domain protein 3-like 1
chr19_+_55996537 0.064 NM_020378
NAT14
N-acetyltransferase 14 (GCN5-related, putative)
chr7_+_150782881 0.062 AGAP3
ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
chr1_-_177939049 0.062 NM_033127
SEC16B
SEC16 homolog B (S. cerevisiae)
chr3_+_141496949 0.061 NM_139209
GRK7
G protein-coupled receptor kinase 7
chr6_-_32634287 0.061 NM_001243961
NM_002123
HLA-DQB1

major histocompatibility complex, class II, DQ beta 1

chr7_-_126883568 0.060 NM_000845
GRM8
glutamate receptor, metabotropic 8
chr5_+_147715121 0.059 NM_001040433
SPINK9
serine peptidase inhibitor, Kazal type 9

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
173.27 1.56e-03 GO:0009881 photoreceptor activity