Motif ID: PRDM1.p3

Z-value: 2.328


Transcription factors associated with PRDM1.p3:

Gene SymbolEntrez IDGene Name
PRDM1 639 PR domain containing 1, with ZNF domain

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
PRDM1hg19_v1_chr6_+_106546736_1065468730.395.9e-04Click!


Activity profile for motif PRDM1.p3.

activity profile for motif PRDM1.p3


Sorted Z-values histogram for motif PRDM1.p3

Sorted Z-values for motif PRDM1.p3



Network of associatons between targets according to the STRING database.



First level regulatory network of PRDM1.p3

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_+_212781969 79.537 NM_001040619
NM_001206484
NM_001206488
NM_001674
ATF3



activating transcription factor 3



chr1_+_212782103 70.442 ATF3
activating transcription factor 3
chr20_-_48099178 28.033 NM_004975
KCNB1
potassium voltage-gated channel, Shab-related subfamily, member 1
chr22_-_36556781 25.530 NM_145640
APOL3
apolipoprotein L, 3
chr6_+_126240369 23.820 NM_001199622
NCOA7
nuclear receptor coactivator 7
chr4_+_186990308 22.278 NM_003265
TLR3
toll-like receptor 3
chr19_+_49977465 20.937 NM_001204502
NM_001459
FLT3LG

fms-related tyrosine kinase 3 ligand

chr5_+_131746579 20.525 C5orf56
chromosome 5 open reading frame 56
chr22_-_30642683 20.182 NM_002309
LIF
leukemia inhibitory factor (cholinergic differentiation factor)
chr1_+_159796506 17.135 SLAMF8
SLAM family member 8
chr10_+_91061705 14.142 NM_001547
IFIT2
interferon-induced protein with tetratricopeptide repeats 2
chr4_+_142557722 13.728 NM_000585
NM_172175
IL15

interleukin 15

chr5_-_142815076 13.327 NM_001018074
NM_001018075
NM_001018077
NR3C1


nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)


chr19_+_49977817 13.298 NM_001204503
FLT3LG
fms-related tyrosine kinase 3 ligand
chr11_+_113931228 12.252 NM_001018011
ZBTB16
zinc finger and BTB domain containing 16
chr1_-_221915393 12.046 DUSP10
dual specificity phosphatase 10
chr1_-_221915426 11.874 DUSP10
dual specificity phosphatase 10
chr3_-_49851217 11.706 UBA7
ubiquitin-like modifier activating enzyme 7
chr8_-_145060563 11.639 PARP10
poly (ADP-ribose) polymerase family, member 10
chr17_+_3379295 11.622 NM_000049
ASPA
aspartoacylase
chr4_-_186578122 11.266 NM_001145674
NM_001145675
SORBS2

sorbin and SH3 domain containing 2

chr6_+_32821924 10.305 NM_002800
PSMB9
proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2)
chr3_-_49851356 9.814 NM_003335
UBA7
ubiquitin-like modifier activating enzyme 7
chr4_+_87856152 9.711 NM_001166693
AFF1
AF4/FMR2 family, member 1
chrX_+_102883647 9.488 NM_001006640
TCEAL1
transcription elongation factor A (SII)-like 1
chr1_-_8075678 9.288 ERRFI1
ERBB receptor feedback inhibitor 1
chr3_+_8543508 9.235 NM_014583
LMCD1
LIM and cysteine-rich domains 1
chr1_-_221915458 9.177 NM_007207
NM_144729
DUSP10

dual specificity phosphatase 10

chr4_-_186577858 8.943 SORBS2
sorbin and SH3 domain containing 2
chr1_+_159796478 8.920 NM_020125
SLAMF8
SLAM family member 8
chr11_+_63304272 8.579 NM_004585
RARRES3
retinoic acid receptor responder (tazarotene induced) 3
chr5_+_73109342 8.504 NM_001244364
RGNEF
190 kDa guanine nucleotide exchange factor
chr8_+_144640476 8.354 NM_024736
GSDMD
gasdermin D
chr1_-_111746917 8.067 DENND2D
DENN/MADD domain containing 2D
chr10_+_123754141 7.882 TACC2
transforming, acidic coiled-coil containing protein 2
chr3_+_8543539 7.802 LMCD1
LIM and cysteine-rich domains 1
chrX_-_118827060 7.243 SEPT6
septin 6
chr21_+_34144410 7.161 C21orf49
chromosome 21 open reading frame 49
chrX_-_118827322 6.951 NM_015129
NM_145799
NM_145800
NM_145802
SEPT6



septin 6



chr2_-_190044330 6.931 NM_000393
COL5A2
collagen, type V, alpha 2
chr3_+_69915374 6.929 NM_198177
MITF
microphthalmia-associated transcription factor
chr3_+_113616317 6.867 NM_001172105
GRAMD1C
GRAM domain containing 1C
chr9_+_123850573 6.733 NM_007018
CNTRL
centriolin
chr5_+_96212167 6.707 ERAP2
endoplasmic reticulum aminopeptidase 2
chrX_+_10124984 6.689 NM_001830
CLCN4
chloride channel 4
chr11_+_71709951 6.609 NM_001039659
NM_001039660
NM_173044
NM_005699
NM_173042
IL18BP




interleukin 18 binding protein




chrX_+_102883891 6.604 NM_001006639
NM_004780
TCEAL1

transcription elongation factor A (SII)-like 1

chr2_+_205410716 6.581 PARD3B
par-3 partitioning defective 3 homolog B (C. elegans)
chr9_+_97766414 6.533 C9orf3
chromosome 9 open reading frame 3
chrX_-_118827116 6.501 SEPT6
septin 6
chr3_+_51977286 6.481 PARP3
poly (ADP-ribose) polymerase family, member 3
chr10_+_114135937 6.325 NM_016234
ACSL5
acyl-CoA synthetase long-chain family member 5
chr1_+_110453456 6.319 CSF1
colony stimulating factor 1 (macrophage)
chr10_+_114135965 6.316 ACSL5
acyl-CoA synthetase long-chain family member 5
chr10_+_91092238 6.238 NM_001031683
IFIT3
interferon-induced protein with tetratricopeptide repeats 3
chrX_-_118827155 6.234 SEPT6
septin 6
chr6_-_33281847 6.182 TAPBP
TAP binding protein (tapasin)
chr5_-_37184945 6.106 C5orf42
chromosome 5 open reading frame 42
chr6_-_33281790 6.008 TAPBP
TAP binding protein (tapasin)
chr14_-_23479328 5.967 NM_001130706
NM_001130708
NM_021944
C14orf93


chromosome 14 open reading frame 93


chr20_+_13976263 5.852 MACROD2
MACRO domain containing 2
chr6_-_33282006 5.819 NM_003190
NM_172208
NM_172209
TAPBP


TAP binding protein (tapasin)


chr15_+_85144219 5.812 NM_001007072
NM_017894
NM_181877
ZSCAN2


zinc finger and SCAN domain containing 2


chr8_-_29120571 5.440 NM_015254
KIF13B
kinesin family member 13B
chr12_-_57824787 5.374 R3HDM2
R3H domain containing 2
chr3_+_51976274 5.346 NM_001003931
NM_005485
PARP3

poly (ADP-ribose) polymerase family, member 3

chr1_+_222817634 5.285 MIA3
melanoma inhibitory activity family, member 3
chr13_+_108921976 5.242 NM_001145645
NM_006573
TNFSF13B

tumor necrosis factor (ligand) superfamily, member 13b

chr2_-_99552677 5.207 NM_207362
C2orf55
chromosome 2 open reading frame 55
chr15_-_37393364 5.063 NM_001220482
NM_002399
MEIS2

Meis homeobox 2

chr1_+_167905921 5.026 DCAF6
DDB1 and CUL4 associated factor 6
chr16_+_50775960 5.018 NM_001042355
NM_015247
CYLD

cylindromatosis (turban tumor syndrome)

chr16_+_50776012 4.963 NM_001042412
CYLD
cylindromatosis (turban tumor syndrome)
chr12_+_6561176 4.942 NM_018009
TAPBPL
TAP binding protein-like
chr10_+_63808968 4.936 NM_001244638
ARID5B
AT rich interactive domain 5B (MRF1-like)
chr1_-_44497132 4.890 NM_001024845
SLC6A9
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr11_+_5646206 4.844 NM_021616
TRIM34
tripartite motif containing 34
chr9_+_109625347 4.791 NM_021224
ZNF462
zinc finger protein 462
chr1_+_110453232 4.740 NM_000757
NM_172210
NM_172212
CSF1


colony stimulating factor 1 (macrophage)


chr3_-_160101443 4.735 NM_001190242
IFT80
intraflagellar transport 80 homolog (Chlamydomonas)
chr11_+_65190267 4.717 NEAT1
nuclear paraspeckle assembly transcript 1 (non-protein coding)
chr22_-_31688329 4.667 NM_001135911
NM_052880
PIK3IP1

phosphoinositide-3-kinase interacting protein 1

chr19_-_47735858 4.618 NM_001127240
NM_001127241
NM_001127242
BBC3


BCL2 binding component 3


chr7_-_105319608 4.611 NM_138495
ATXN7L1
ataxin 7-like 1
chr1_-_182361311 4.570 NM_001033044
NM_002065
GLUL

glutamate-ammonia ligase

chr11_+_65190272 4.496


chr18_+_55816546 4.424 NM_001144965
NM_001144968
NM_001144969
NM_001144971
NEDD4L



neural precursor cell expressed, developmentally down-regulated 4-like



chr4_-_100242487 4.354 NM_000668
ADH1A
ADH1B
alcohol dehydrogenase 1A (class I), alpha polypeptide
alcohol dehydrogenase 1B (class I), beta polypeptide
chr1_+_167905796 4.351 NM_001017977
NM_001198956
NM_001198957
NM_018442
DCAF6



DDB1 and CUL4 associated factor 6



chr1_-_44497028 4.344 SLC6A9
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr2_+_205410465 4.303 NM_057177
NM_152526
NM_205863
PARD3B


par-3 partitioning defective 3 homolog B (C. elegans)


chr2_+_205410556 4.248 PARD3B
par-3 partitioning defective 3 homolog B (C. elegans)
chr2_+_234526290 4.228 NM_019076
UGT1A8
UDP glucuronosyltransferase 1 family, polypeptide A8
chr10_-_94003002 4.206 NM_001178137
CPEB3
cytoplasmic polyadenylation element binding protein 3
chr13_+_31309690 4.181 ALOX5AP
arachidonate 5-lipoxygenase-activating protein
chr3_-_187871816 4.177 LPP-AS2
LPP antisense RNA 2 (non-protein coding)
chr5_-_96143573 4.152 ERAP1
endoplasmic reticulum aminopeptidase 1
chr11_+_46402333 4.086 NM_001012334
MDK
midkine (neurite growth-promoting factor 2)
chrX_-_63005212 3.970 NM_001173479
ARHGEF9
Cdc42 guanine nucleotide exchange factor (GEF) 9
chr2_-_152146373 3.958 NM_004688
NMI
N-myc (and STAT) interactor
chr11_-_85430117 3.862 NM_206929
SYTL2
synaptotagmin-like 2
chr5_-_34043234 3.862 NM_030945
NM_181435
C1QTNF3

C1q and tumor necrosis factor related protein 3

chr10_-_35103894 3.844 NM_001184785
NM_001184786
NM_001184787
NM_001184788
NM_001184789
NM_001184790
NM_001184791
NM_001184792
NM_001184793
NM_001184794
NM_019619
PARD3










par-3 partitioning defective 3 homolog (C. elegans)










chr14_+_24605366 3.754 NM_006263
NM_176783
PSME1

proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)

chr15_-_56209305 3.622 NM_198400
NEDD4
neural precursor cell expressed, developmentally down-regulated 4
chr14_+_24605393 3.618 PSME1
proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
chr6_+_26440699 3.590 NM_001242803
NM_006994
NM_197974
BTN3A3


butyrophilin, subfamily 3, member A3


chr2_-_231084600 3.497 NM_004509
NM_004510
NM_080424
SP110


SP110 nuclear body protein


chr16_-_73092533 3.459 NM_001164766
ZFHX3
zinc finger homeobox 3
chr22_+_39436608 3.445 NM_001006666
NM_145298
APOBEC3F

apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3F

chr10_+_91087601 3.418 NM_001549
IFIT3
interferon-induced protein with tetratricopeptide repeats 3
chr2_+_234545099 3.340 NM_019075
UGT1A10
UDP glucuronosyltransferase 1 family, polypeptide A10
chr13_+_31309644 3.198 NM_001629
ALOX5AP
arachidonate 5-lipoxygenase-activating protein
chr15_-_80207597 3.171 NM_001100879
ST20
suppressor of tumorigenicity 20
chr4_-_185395616 3.166 NM_002199
IRF2
interferon regulatory factor 2
chr5_-_96143689 3.164 NM_001040458
NM_016442
ERAP1

endoplasmic reticulum aminopeptidase 1

chr2_+_132480063 3.082 NM_013310
C2orf27A
chromosome 2 open reading frame 27A
chr19_-_12992249 3.079 NM_001375
DNASE2
deoxyribonuclease II, lysosomal
chr2_-_145275086 3.076 ZEB2
zinc finger E-box binding homeobox 2
chr11_+_28131830 3.013 METTL15
methyltransferase like 15
chr21_-_35899046 3.007 NM_203418
RCAN1
regulator of calcineurin 1
chr11_+_123986103 2.906 NM_001130142
NM_014622
NM_198315
VWA5A


von Willebrand factor A domain containing 5A


chr17_-_38520941 2.882 NM_152219
GJD3
gap junction protein, delta 3, 31.9kDa
chr1_-_150780705 2.861 NM_000396
CTSK
cathepsin K
chr1_+_159796654 2.853 SLAMF8
SLAM family member 8
chr1_+_104159953 2.791 NM_000699
AMY2A
amylase, alpha 2A (pancreatic)
chr3_+_174577069 2.788 NM_207015
NAALADL2
N-acetylated alpha-linked acidic dipeptidase-like 2
chr8_-_9009050 2.765 NM_001201329
PPP1R3B
protein phosphatase 1, regulatory subunit 3B
chr10_+_5238756 2.631 NM_001818
AKR1C4
aldo-keto reductase family 1, member C4 (chlordecone reductase; 3-alpha hydroxysteroid dehydrogenase, type I; dihydrodiol dehydrogenase 4)
chr6_-_32811773 2.547 NM_148919
PSMB8
proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7)
chr2_-_45795104 2.379 SRBD1
S1 RNA binding domain 1
chr4_-_74853819 2.348 NM_002704
PPBP
pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
chr14_+_24701624 2.348 NM_001002000
NM_001002001
GMPR2

guanosine monophosphate reductase 2

chr17_-_48271365 2.340


chr20_+_13976014 2.338 NM_080676
MACROD2
MACRO domain containing 2
chr20_+_10015696 2.328 NM_022096
NM_198798
ANKRD5

ankyrin repeat domain 5

chr17_+_78237389 2.232


chr13_+_108922205 2.194 TNFSF13B
tumor necrosis factor (ligand) superfamily, member 13b
chr10_-_97321094 2.174 NM_015385
NM_024991
SORBS1

sorbin and SH3 domain containing 1

chr22_+_39417117 2.147 NM_152426
APOBEC3D
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3D
chr1_-_8483701 2.146 NM_001042682
RERE
arginine-glutamic acid dipeptide (RE) repeats
chr2_+_231280870 2.123 NM_001080391
NM_001206701
NM_001206702
NM_001206703
NM_003113
SP100




SP100 nuclear antigen




chr1_+_111889194 2.115 NM_181643
C1orf88
chromosome 1 open reading frame 88
chr12_-_56709831 2.071 NM_001190991
NM_014255
CNPY2

canopy 2 homolog (zebrafish)

chr10_+_18429605 2.046 NM_201593
NM_201596
NM_201597
NM_001167945
NM_201571
NM_201572
CACNB2





calcium channel, voltage-dependent, beta 2 subunit





chr14_-_69262959 1.968 NM_001244701
ZFP36L1
zinc finger protein 36, C3H type-like 1
chr6_+_25962978 1.967 NM_006355
TRIM38
tripartite motif containing 38
chr11_-_28129687 1.963 KIF18A
kinesin family member 18A
chr6_+_32811895 1.937


chr12_+_51318515 1.924 NM_014033
METTL7A
methyltransferase like 7A
chr7_+_55980330 1.917 NM_182633
ZNF713
zinc finger protein 713
chr14_-_69260630 1.888 NM_001244698
NM_004926
ZFP36L1

zinc finger protein 36, C3H type-like 1

chr12_+_102271349 1.882 DRAM1
DNA-damage regulated autophagy modulator 1
chr17_+_41158741 1.812 NM_005533
IFI35
interferon-induced protein 35
chr12_-_49319211 1.795 NM_001143782
NM_016594
FKBP11

FK506 binding protein 11, 19 kDa

chr11_+_35684658 1.791 TRIM44
tripartite motif containing 44
chr1_-_167905078 1.789 BRP44
brain protein 44
chr11_+_28129797 1.786 NM_001113528
NM_152636
METTL15

methyltransferase like 15

chr3_+_9932285 1.780 JAGN1
jagunal homolog 1 (Drosophila)
chr12_-_57505176 1.764 NM_001178078
NM_001178080
NM_001178081
NM_003153
STAT6



signal transducer and activator of transcription 6, interleukin-4 induced



chr22_-_36562224 1.742 NM_145641
NM_145642
APOL3

apolipoprotein L, 3

chr9_+_102677457 1.736 STX17
syntaxin 17
chr4_-_48782264 1.734 FRYL
FRY-like
chr12_+_9142136 1.702 NM_005810
KLRG1
killer cell lectin-like receptor subfamily G, member 1
chr2_-_175260349 1.697 NM_004882
CIR1
corepressor interacting with RBPJ, 1
chr1_-_9129666 1.683 NM_001135585
NM_003039
SLC2A5

solute carrier family 2 (facilitated glucose/fructose transporter), member 5

chr12_+_102271082 1.664 NM_018370
DRAM1
DNA-damage regulated autophagy modulator 1
chr6_-_10412606 1.634 NM_001032280
TFAP2A
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr8_+_97657581 1.610 PGCP
plasma glutamate carboxypeptidase
chr20_-_34638836 1.566 LOC647979
uncharacterized LOC647979
chr1_-_29309092 1.565


chr18_+_20735788 1.556 NM_138375
CABLES1
Cdk5 and Abl enzyme substrate 1
chr15_-_82641705 1.534 NM_001164465
GOLGA6L10
golgin A6 family-like 10
chr7_+_99621083 1.523 ZKSCAN1
zinc finger with KRAB and SCAN domains 1
chr12_-_57505121 1.504 STAT6
signal transducer and activator of transcription 6, interleukin-4 induced
chr1_+_161169104 1.497 NM_004550
NDUFS2
NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase)
chr1_+_19971865 1.491 NM_001204085
NBL1
neuroblastoma, suppression of tumorigenicity 1
chr4_-_153303663 1.484 NM_001013415
FBXW7
F-box and WD repeat domain containing 7
chr11_-_28129646 1.472 KIF18A
kinesin family member 18A
chr6_-_105584982 1.450 NM_001199563
BVES
blood vessel epicardial substance
chr1_+_151372009 1.430 NM_002796
PSMB4
proteasome (prosome, macropain) subunit, beta type, 4
chr1_-_116383692 1.429 NM_005599
NHLH2
nescient helix loop helix 2
chr7_+_5253816 1.428 NM_001033520
WIPI2
WD repeat domain, phosphoinositide interacting 2
chr6_-_105584542 1.427 NM_007073
BVES
blood vessel epicardial substance
chr1_-_148176392 1.419


chr3_+_107241782 1.383 NM_001142568
NM_020235
BBX

bobby sox homolog (Drosophila)

chr19_-_20748540 1.376 NM_001159293
ZNF737
zinc finger protein 737
chr4_-_100140330 1.373 NM_000672
NM_001102470
ADH6

alcohol dehydrogenase 6 (class V)

chr13_+_53216564 1.348 HNRNPA1L2
heterogeneous nuclear ribonucleoprotein A1-like 2
chr12_+_27619742 1.334 NM_001145010
C12orf70
chromosome 12 open reading frame 70
chr12_-_56709656 1.321 CNPY2
canopy 2 homolog (zebrafish)
chr19_-_12992140 1.304 DNASE2
deoxyribonuclease II, lysosomal
chr12_-_57504935 1.301 STAT6
signal transducer and activator of transcription 6, interleukin-4 induced
chr2_+_175260455 1.299 NM_001193528
NM_024583
SCRN3

secernin 3

chr1_-_147931877 1.278 FLJ39739
uncharacterized FLJ39739
chr11_-_5706186 1.248 NM_033034
NM_033092
NM_033093
TRIM5


tripartite motif containing 5


chr1_-_144521169 1.242 FAM91A2
family with sequence similarity 91, member A2
chr16_-_67970734 1.237 NM_002801
PSMB10
proteasome (prosome, macropain) subunit, beta type, 10
chr1_+_19972259 1.213 NM_001204086
NBL1
neuroblastoma, suppression of tumorigenicity 1
chr11_-_58343308 1.207 NM_004811
LPXN
leupaxin

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
94.48 1.68e-05 GO:0002483 antigen processing and presentation of endogenous peptide antigen
94.48 1.68e-05 GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I
67.49 1.16e-04 GO:0019883 antigen processing and presentation of endogenous antigen
36.34 2.28e-03 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I
9.62 5.69e-03 GO:0030330 DNA damage response, signal transduction by p53 class mediator
11.44 9.49e-03 GO:0060337 type I interferon-mediated signaling pathway
11.44 9.49e-03 GO:0071357 cellular response to type I interferon
11.25 1.04e-02 GO:0034340 response to type I interferon
7.11 1.20e-02 GO:0010565 regulation of cellular ketone metabolic process
23.63 1.48e-02 GO:0048002 antigen processing and presentation of peptide antigen
7.73 2.38e-02 GO:0042770 signal transduction in response to DNA damage
2.78 3.63e-02 GO:0051704 multi-organism process
2.45 4.14e-02 GO:0002376 immune system process
118.10 4.90e-02 GO:0008356 asymmetric cell division
118.10 4.90e-02 GO:0010766 negative regulation of sodium ion transport

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
23.63 2.62e-03 GO:0005839 proteasome core complex
9.38 2.34e-02 GO:0000502 proteasome complex

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
22.50 3.98e-03 GO:0004298 threonine-type endopeptidase activity
22.50 3.98e-03 GO:0070003 threonine-type peptidase activity
39.37 7.26e-03 GO:0004022 alcohol dehydrogenase (NAD) activity
118.10 1.08e-02 GO:0019871 sodium channel inhibitor activity
2.42 4.78e-02 GO:0003700 sequence-specific DNA binding transcription factor activity