• All motifs sorted by activity significance
• All samples sorted alphabetically
• Mean activities

• Activities table
• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
• Download the whole report

Motif ID: POU5F1_SOX2{dimer}.p2

Z-value: 1.085

---

Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr15_+_25068793	12.658	NM_022806 NM_022807 NM_022808	SNRPN	small nuclear ribonucleoprotein polypeptide N
chr15_+_25101697	11.439	NM_022805	SNRPN	small nuclear ribonucleoprotein polypeptide N
chr9_+_6215785	8.171	NM_001199640 NM_001199641 NM_033439	IL33	interleukin 33
chr8_-_82395401	7.479	NM_001442	FABP4	fatty acid binding protein 4, adipocyte
chr5_-_64777703	6.429	NM_197941	ADAMTS6	ADAM metallopeptidase with thrombospondin type 1 motif, 6
chr18_+_28898051	6.428	NM_001942	DSG1	desmoglein 1
chr10_-_23633771	6.316	NM_153714	C10orf67	chromosome 10 open reading frame 67
chr4_-_15940362	5.946	NM_005130	FGFBP1	fibroblast growth factor binding protein 1
chr18_-_61329113	5.910	NM_006919	SERPINB3	serpin peptidase inhibitor, clade B (ovalbumin), member 3
chr7_+_1126442	5.834	NM_001039966 NM_001505	GPER	G protein-coupled estrogen receptor 1
chr12_+_20963637	5.052	NM_019844	SLCO1B3	solute carrier organic anion transporter family, member 1B3
chr11_+_69455837	4.622	NM_053056	CCND1	cyclin D1
chr12_+_89744714	4.405		LOC100131490	uncharacterized LOC100131490
chr11_+_69455938	4.307		CCND1	cyclin D1
chr8_+_32579350	4.223	NM_001159996	NRG1	neuregulin 1
chr2_+_74120132	4.016		ACTG2	actin, gamma 2, smooth muscle, enteric
chr12_-_47473424	3.934	NM_001143668 NM_181847	AMIGO2	adhesion molecule with Ig-like domain 2
chr11_+_69455884	3.815		CCND1	cyclin D1
chr5_+_140254930	3.790	NM_018903 NM_031864	PCDHA12	protocadherin alpha 12
chr7_+_89843133	3.767	NM_001040666	STEAP2	STEAP family member 2, metalloreductase
chr11_+_69455978	3.762		CCND1	cyclin D1
chr2_-_75062214	3.724
chr12_-_50616425	3.697	NM_001113547	LIMA1	LIM domain and actin binding 1
chr9_-_140196702	3.690	NM_001004354	NRARP	NOTCH-regulated ankyrin repeat protein
chr2_+_74120092	3.677	NM_001199893 NM_001615	ACTG2	actin, gamma 2, smooth muscle, enteric
chr9_+_21409132	3.603	NM_002170	IFNA8	interferon, alpha 8
chr14_-_101036130	3.599	NM_020836	BEGAIN	brain-enriched guanylate kinase-associated homolog (rat)
chr4_+_70796798	3.587	NM_001025104 NM_001890	CSN1S1	casein alpha s1
chr12_+_7942025	3.549		NANOG	Nanog homeobox
chr7_+_28452143	3.461	NM_182898	CREB5	cAMP responsive element binding protein 5
chr2_+_166326156	3.307	NM_001172173	CSRNP3	cysteine-serine-rich nuclear protein 3
chr2_-_231989755	3.272	NM_000867	HTR2B	5-hydroxytryptamine (serotonin) receptor 2B
chr12_-_28124915	3.265	NM_002820 NM_198965	PTHLH	parathyroid hormone-like hormone
chr1_-_93399531	3.231
chr13_-_86373328	3.197	NM_032229	SLITRK6	SLIT and NTRK-like family, member 6
chr20_-_9819406	3.190	NM_020341 NM_177990	PAK7	p21 protein (Cdc42/Rac)-activated kinase 7
chr12_+_7941994	3.154	NM_024865	NANOG	Nanog homeobox
chr7_+_142919129	3.040	NM_176882	TAS2R40	taste receptor, type 2, member 40
chr15_+_25230199	3.011		PAR5	Prader-Willi/Angelman syndrome-5
chr17_+_27370155	2.955		PIPOX	pipecolic acid oxidase
chr1_-_177133950	2.929	NM_004319 NM_207108	ASTN1	astrotactin 1
chr6_-_66289696	2.875	NM_198283	EYS	eyes shut homolog (Drosophila)
chr12_-_8815370	2.843	NM_003480	MFAP5	microfibrillar associated protein 5
chr1_-_177134042	2.843		ASTN1	astrotactin 1
chr10_+_91137812	2.819	NM_001010987	IFIT1B	interferon-induced protein with tetratricopeptide repeats 1B
chr17_+_27369917	2.803	NM_016518	PIPOX	pipecolic acid oxidase
chr2_+_36923832	2.735	NM_001177969 NM_001177970 NM_001177971 NM_001177972 NM_053276	VIT	vitrin
chr12_+_48876285	2.730	NM_152319	C12orf54	chromosome 12 open reading frame 54
chr18_-_3845295	2.710	NM_001003809 NM_001242765 NM_001242766	DLGAP1	discs, large (Drosophila) homolog-associated protein 1
chr14_-_106733392	2.685		IGHG1 IGHG3	immunoglobulin heavy constant gamma 1 (G1m marker) immunoglobulin heavy constant gamma 3 (G3m marker)
chr7_+_29519485	2.591	NM_001039936	CHN2	chimerin (chimaerin) 2
chr14_-_107170076	2.555		IGHV1-69 IGHG1	immunoglobulin heavy variable 1-69 immunoglobulin heavy constant gamma 1 (G1m marker)
chr2_+_68592432	2.525		PLEK	pleckstrin
chr19_+_42259397	2.491	NM_002483	CEACAM6	carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
chr11_-_35441501	2.484	NM_001195728 NM_001252652	SLC1A2	solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr1_+_162602198	2.469	NM_001014796 NM_006182	DDR2	discoidin domain receptor tyrosine kinase 2
chr16_-_21314371	2.469	NM_001014444 NM_001888	CRYM	crystallin, mu
chr6_-_31560497	2.467	NM_001145466 NM_001145467 NM_147130	NCR3	natural cytotoxicity triggering receptor 3
chr5_+_59784004	2.461		PART1	prostate androgen-regulated transcript 1 (non-protein coding)
chr6_-_108145507	2.455	NM_198081	SCML4	sex comb on midleg-like 4 (Drosophila)
chr3_+_63428752	2.452	NM_144642	SYNPR	synaptoporin
chr7_+_47694841	2.448	NM_001123065	C7orf65	chromosome 7 open reading frame 65
chr1_-_183622447	2.389	NM_203454	APOBEC4	apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 4 (putative)
chr8_-_93029864	2.368	NM_175636	RUNX1T1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr4_+_88720701	2.338	NM_004967	IBSP	integrin-binding sialoprotein
chr13_+_23755059	2.320	NM_000231	SGCG	sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
chr17_+_60457913	2.287	NM_173503	EFCAB3	EF-hand calcium binding domain 3
chr7_-_122339186	2.285	NM_139175	RNF133	ring finger protein 133
chr6_+_154897419	2.265
chr11_-_59633942	2.265	NM_001062	TCN1	transcobalamin I (vitamin B12 binding protein, R binder family)
chr11_-_128457452	2.261	NM_001143820	ETS1	v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)
chr7_+_80267922	2.251		CD36	CD36 molecule (thrombospondin receptor)
chr2_-_239148626	2.251	NM_001142853 NM_018645	HES6	hairy and enhancer of split 6 (Drosophila)
chr19_-_57678855	2.244	NM_001012729	DUXA	double homeobox A
chr13_-_28543290	2.235	NM_001265	CDX2	caudal type homeobox 2
chr10_+_114043413	2.199	NM_058222	TECTB	tectorin beta
chrX_+_135570124	2.175	NM_001727	BRS3	bombesin-like receptor 3
chr6_-_43276529	2.171	NM_206922	CRIP3	cysteine-rich protein 3
chr1_+_50574589	2.127	NM_001144774 NM_021952	ELAVL4	ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr10_+_7745284	2.127		ITIH2	inter-alpha-trypsin inhibitor heavy chain 2
chr3_+_108021331	2.120	NM_007072	HHLA2	HERV-H LTR-associating 2
chr8_-_82024277	2.119	NM_018440	PAG1	phosphoprotein associated with glycosphingolipid microdomains 1
chrX_+_88002225	2.109	NM_001184771 NM_033048	CPXCR1	CPX chromosome region, candidate 1
chr6_+_32407618	2.077	NM_019111	HLA-DRA	major histocompatibility complex, class II, DR alpha
chr17_+_32582295	2.076	NM_002982	CCL2	chemokine (C-C motif) ligand 2
chr10_+_7745229	2.065	NM_002216	ITIH2	inter-alpha-trypsin inhibitor heavy chain 2
chr14_-_106967528	2.062		IGHA1 IGHA2 IGHG1 IGHM	immunoglobulin heavy constant alpha 1 immunoglobulin heavy constant alpha 2 (A2m marker) immunoglobulin heavy constant gamma 1 (G1m marker) immunoglobulin heavy constant mu
chr15_-_20747113	2.025	NM_001145004	GOLGA6L6	golgin A6 family-like 6
chr13_-_103411421	2.017	NM_001146197	CCDC168	coiled-coil domain containing 168
chr2_+_68592317	2.015	NM_002664	PLEK	pleckstrin
chr1_-_24239758	2.007	NM_001841	CNR2	cannabinoid receptor 2 (macrophage)
chr13_-_70682458	1.995	NM_020866	KLHL1	kelch-like 1 (Drosophila)
chr10_+_7745354	1.992		ITIH2	inter-alpha-trypsin inhibitor heavy chain 2
chr19_+_7828034	1.975	NM_001144904 NM_001144905 NM_001144906 NM_001144907 NM_001144908 NM_001144909 NM_001144910 NM_001144911 NM_014257	CLEC4M	C-type lectin domain family 4, member M
chr3_+_45927995	1.971	NM_006641 NM_031200	CCR9	chemokine (C-C motif) receptor 9
chr7_+_37723378	1.958
chr4_-_46125929	1.957	NM_173536	GABRG1	gamma-aminobutyric acid (GABA) A receptor, gamma 1
chr7_-_92855780	1.923	NM_001039372	HEPACAM2	HEPACAM family member 2
chr2_-_161056573	1.922	NM_000888	ITGB6	integrin, beta 6
chr14_-_106774311	1.917		IGHA1	immunoglobulin heavy constant alpha 1
chr5_+_161277702	1.913	NM_001127648	GABRA1	gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr10_+_7745325	1.905		ITIH2	inter-alpha-trypsin inhibitor heavy chain 2
chr3_-_9920633	1.883	NM_022094	CIDEC	cell death-inducing DFFA-like effector c
chr13_-_28543143	1.863		CDX2	caudal type homeobox 2
chr3_+_100238063	1.860		TMEM45A	transmembrane protein 45A
chr8_-_86253863	1.840	NM_001164830	CA1	carbonic anhydrase I
chr4_-_68829143	1.836	NM_001114387 NM_182606	TMPRSS11A	transmembrane protease, serine 11A
chr11_-_105010460	1.824	NM_021571	CARD18	caspase recruitment domain family, member 18
chr8_-_26724748	1.822		ADRA1A	adrenergic, alpha-1A-, receptor
chr10_-_69455926	1.817	NM_013266	CTNNA3	catenin (cadherin-associated protein), alpha 3
chr1_-_157670280	1.816	NM_052939	FCRL3	Fc receptor-like 3
chr3_+_121312169	1.816	NM_016298	FBXO40	F-box protein 40
chr11_-_49229994	1.802	NM_001014986 NM_001193471 NM_001193472 NM_001193473 NM_004476	FOLH1	folate hydrolase (prostate-specific membrane antigen) 1
chr2_-_161056762	1.801		ITGB6	integrin, beta 6
chr5_-_35230822	1.788	NM_000949	PRLR	prolactin receptor
chr11_+_60524339	1.786	NM_001098835 NM_152717	MS4A15	membrane-spanning 4-domains, subfamily A, member 15
chr6_+_47749774	1.781	NM_181744	OPN5	opsin 5
chrX_+_135383121	1.773	NM_153834	GPR112	G protein-coupled receptor 112
chrX_+_2958274	1.768	NM_001201538	ARSF	arylsulfatase F
chr15_+_22736245	1.763	NM_001001413	GOLGA6L1	golgin A6 family-like 1
chr6_-_22297729	1.760	NM_000948	PRL	prolactin
chr1_-_108786663	1.741	NM_001143989	NBPF4 NBPF6	neuroblastoma breakpoint family, member 4 neuroblastoma breakpoint family, member 6
chr14_-_106967080	1.737		IGHG1	immunoglobulin heavy constant gamma 1 (G1m marker)
chrX_+_128913881	1.735	NM_018990	SASH3	SAM and SH3 domain containing 3
chr3_+_2280512	1.732	NM_001206955	CNTN4	contactin 4
chr9_-_75567915	1.731		ALDH1A1	aldehyde dehydrogenase 1 family, member A1
chr11_-_118047336	1.721	NM_004588	SCN2B	sodium channel, voltage-gated, type II, beta
chr3_-_152058778	1.718	NM_001123228	TMEM14E	transmembrane protein 14E
chr9_-_33465191	1.718		NOL6	nucleolar protein family 6 (RNA-associated)
chr12_-_27599557	1.705		ARNTL2	aryl hydrocarbon receptor nuclear translocator-like 2
chr14_-_107170400	1.705		IGHV4-31 IGHV1-69 IGHA1 IGHG1 IGHG3 IGHM	immunoglobulin heavy variable 4-31 immunoglobulin heavy variable 1-69 immunoglobulin heavy constant alpha 1 immunoglobulin heavy constant gamma 1 (G1m marker) immunoglobulin heavy constant gamma 3 (G3m marker) immunoglobulin heavy constant mu
chr12_+_25205488	1.695		LRMP	lymphoid-restricted membrane protein
chr1_-_178840079	1.694	NM_004673	ANGPTL1	angiopoietin-like 1
chr14_-_106641585	1.693		IGHV4-31 IGHA1 IGHA2 IGHG1	immunoglobulin heavy variable 4-31 immunoglobulin heavy constant alpha 1 immunoglobulin heavy constant alpha 2 (A2m marker) immunoglobulin heavy constant gamma 1 (G1m marker)
chr13_-_28543423	1.684		CDX2	caudal type homeobox 2
chr12_-_8815266	1.679		MFAP5	microfibrillar associated protein 5
chr3_-_42917191	1.676		CYP8B1	cytochrome P450, family 8, subfamily B, polypeptide 1
chr6_-_76782204	1.668	NM_001563	IMPG1	interphotoreceptor matrix proteoglycan 1
chr7_-_84751246	1.651	NM_152754	SEMA3D	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D
chr18_+_61420276	1.647	NM_001040147	SERPINB7	serpin peptidase inhibitor, clade B (ovalbumin), member 7
chr8_-_93107881	1.635	NM_001198625 NM_001198626 NM_001198627 NM_001198631 NM_001198634 NM_001198679	RUNX1T1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr11_+_8060179	1.633	NM_003320	TUB	tubby homolog (mouse)
chrX_+_65235279	1.611
chrX_+_128913897	1.600		SASH3	SAM and SH3 domain containing 3
chr7_-_83270746	1.593	NM_001178129	SEMA3E	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
chr3_+_2933898	1.589	NM_001206956 NM_175613	CNTN4	contactin 4
chr16_+_76311175	1.589	NM_033401	CNTNAP4	contactin associated protein-like 4
chr19_+_58513428	1.588		LOC100128398	uncharacterized LOC100128398
chr3_+_156008775	1.585	NM_172159	KCNAB1	potassium voltage-gated channel, shaker-related subfamily, beta member 1
chr14_-_106452693	1.581		IGHG1	immunoglobulin heavy constant gamma 1 (G1m marker)
chr12_-_21487831	1.569	NM_021094	SLCO1A2	solute carrier organic anion transporter family, member 1A2
chr6_+_12716887	1.565		PHACTR1	phosphatase and actin regulator 1
chr6_-_138820580	1.561
chr12_-_113909876	1.559	NM_022363	LHX5	LIM homeobox 5
chr11_-_56310732	1.554	NM_001005245	OR5M11	olfactory receptor, family 5, subfamily M, member 11
chr10_-_52645430	1.553	NM_001198818 NM_001198819 NM_001198820 NM_014576 NM_138932 NM_138933	A1CF	APOBEC1 complementation factor
chr11_-_6024377	1.546	NM_001005179	OR56A4	olfactory receptor, family 56, subfamily A, member 4
chr15_+_80733579	1.540		ARNT2	aryl-hydrocarbon receptor nuclear translocator 2
chr4_+_15341559	1.507	NM_001135170	C1QTNF7	C1q and tumor necrosis factor related protein 7
chr2_-_239148545	1.500		HES6	hairy and enhancer of split 6 (Drosophila)
chr2_-_178973065	1.487	NM_001077197	PDE11A	phosphodiesterase 11A
chr5_+_140809957	1.487		PCDHGA12	protocadherin gamma subfamily A, 12
chr2_-_2334887	1.482	NM_015025	MYT1L	myelin transcription factor 1-like
chr14_-_106725620	1.477		IGHV4-31 IGHV3-23 IGHA1 IGHG1 IGHM	immunoglobulin heavy variable 4-31 immunoglobulin heavy variable 3-23 immunoglobulin heavy constant alpha 1 immunoglobulin heavy constant gamma 1 (G1m marker) immunoglobulin heavy constant mu
chr13_-_99959649	1.476	NM_004951	GPR183	G protein-coupled receptor 183
chr12_-_90049818	1.464	NM_001001323 NM_001682	ATP2B1	ATPase, Ca++ transporting, plasma membrane 1
chr12_+_48866447	1.464	NM_012404	ANP32D	acidic (leucine-rich) nuclear phosphoprotein 32 family, member D
chr10_+_5488521	1.449	NM_005863	NET1	neuroepithelial cell transforming 1
chr4_+_69313166	1.442	NM_014058	TMPRSS11E	transmembrane protease, serine 11E
chr9_-_21166609	1.439	NM_002175	IFNA21	interferon, alpha 21
chr12_+_51347781	1.427	NM_001109619	HIGD1C	HIG1 hypoxia inducible domain family, member 1C
chr6_+_26104103	1.417	NM_003542	HIST2H4B HIST1H4C	histone cluster 2, H4b histone cluster 1, H4c
chr1_+_16083132	1.416		FBLIM1	filamin binding LIM protein 1
chr7_+_136553398	1.413	NM_001006627 NM_001006630	CHRM2	cholinergic receptor, muscarinic 2
chr5_+_76114832	1.405	NM_005242	F2RL1	coagulation factor II (thrombin) receptor-like 1
chr6_-_47254143	1.405		TNFRSF21	tumor necrosis factor receptor superfamily, member 21
chr6_+_123100860	1.395		FABP7	fatty acid binding protein 7, brain
chr11_+_6897855	1.387	NM_207186	OR10A4	olfactory receptor, family 10, subfamily A, member 4
chr3_+_130279177	1.383	NM_001102608	COL6A6	collagen, type VI, alpha 6
chr10_-_98119058	1.381	NM_001040102 NM_001040103 NM_033207	OPALIN	oligodendrocytic myelin paranodal and inner loop protein
chr5_+_125758818	1.369	NM_001146320 NM_001146321 NM_023927	GRAMD3	GRAM domain containing 3
chr12_-_102874158	1.361		IGF1	insulin-like growth factor 1 (somatomedin C)
chr6_+_167525294	1.359	NM_004367	CCR6	chemokine (C-C motif) receptor 6
chr12_-_102874340	1.355		IGF1	insulin-like growth factor 1 (somatomedin C)
chr5_+_76114881	1.350		F2RL1	coagulation factor II (thrombin) receptor-like 1
chr1_-_156265395	1.346	NM_144580	C1orf85	chromosome 1 open reading frame 85
chr8_+_42552561	1.329	NM_000749	CHRNB3	cholinergic receptor, nicotinic, beta 3
chr8_-_93075190	1.328	NM_004349	RUNX1T1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr5_-_94417185	1.325		MCTP1	multiple C2 domains, transmembrane 1
chr16_-_46782104	1.320	NM_182493	MYLK3	myosin light chain kinase 3
chr3_-_87325611	1.306	NM_000306 NM_001122757	POU1F1	POU class 1 homeobox 1
chr1_+_112938799	1.304	NM_018704	CTTNBP2NL	CTTNBP2 N-terminal like
chr1_-_150738292	1.300	NM_001199739 NM_004079	CTSS	cathepsin S
chr10_+_77542518	1.296	NM_032024	C10orf11	chromosome 10 open reading frame 11
chr9_-_100700422	1.291	NM_197978	HEMGN	hemogen
chr6_+_26045611	1.290	NM_003531	HIST1H3C	histone cluster 1, H3c
chr16_-_21663908	1.286		IGSF6	immunoglobulin superfamily, member 6
chr12_-_102874373	1.277	NM_000618 NM_001111283 NM_001111285	IGF1	insulin-like growth factor 1 (somatomedin C)
chr12_+_25205180	1.273	NM_001204126 NM_001204127 NM_006152	LRMP	lymphoid-restricted membrane protein
chrX_+_150903217	1.269	NM_005140	CNGA2	cyclic nucleotide gated channel alpha 2

Gene overrepresentation in process category:

Enrichment	P-value	GO Accession	GO Term
1.48	2.36e-03	GO:0050896	response to stimulus
2.87	4.85e-03	GO:0006955	immune response
2.37	5.68e-03	GO:0002376	immune system process
1.47	3.20e-02	GO:0032501	multicellular organismal process

Gene overrepresentation in compartment category:

Enrichment	P-value	GO Accession	GO Term
2.18	1.05e-05	GO:0005576	extracellular region
1.72	1.22e-05	GO:0071944	cell periphery
1.72	1.46e-05	GO:0005886	plasma membrane
2.00	1.95e-04	GO:0044459	plasma membrane part
2.42	2.35e-04	GO:0005887	integral to plasma membrane
2.38	3.54e-04	GO:0031226	intrinsic to plasma membrane
2.55	4.12e-04	GO:0044421	extracellular region part
1.44	8.23e-03	GO:0031224	intrinsic to membrane
2.51	8.74e-03	GO:0005615	extracellular space
1.35	3.30e-02	GO:0044425	membrane part
1.40	3.97e-02	GO:0016021	integral to membrane

Gene overrepresentation in function category:

Enrichment	P-value	GO Accession	GO Term
14.86	7.30e-05	GO:0003823	antigen binding
2.21	1.76e-04	GO:0004872	receptor activity
2.03	3.73e-04	GO:0004871	signal transducer activity
2.03	3.73e-04	GO:0060089	molecular transducer activity
2.15	1.06e-02	GO:0004888	transmembrane receptor activity