Motif ID: POU5F1.p2

Z-value: 1.663


Transcription factors associated with POU5F1.p2:

Gene SymbolEntrez IDGene Name
POU5F1 5460 POU class 5 homeobox 1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
POU5F1hg19_v1_chr6_-_31134614_311346140.361.7e-03Click!


Activity profile for motif POU5F1.p2.

activity profile for motif POU5F1.p2


Sorted Z-values histogram for motif POU5F1.p2

Sorted Z-values for motif POU5F1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of POU5F1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr17_+_67410825 36.184 NM_002758
MAP2K6
mitogen-activated protein kinase kinase 6
chr16_-_79634610 17.379 NM_001031804
NM_005360
MAF

v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian)

chr17_-_38978824 15.171 NM_000421
KRT10
keratin 10
chr1_+_164528914 13.330 PBX1
pre-B-cell leukemia homeobox 1
chr1_-_108231122 12.248 NM_001079874
VAV3
vav 3 guanine nucleotide exchange factor
chr10_-_64576123 11.618 NM_000399
NM_001136177
NM_001136179
EGR2


early growth response 2


chr10_-_64576074 11.375 EGR2
early growth response 2
chr10_-_64578926 10.429 NM_001136178
EGR2
early growth response 2
chr1_+_61542790 10.298


chr1_-_153363544 9.734 NM_002964
S100A8
S100 calcium binding protein A8
chr10_-_98031154 8.631 NM_001114094
NM_013314
BLNK

B-cell linker

chr3_-_64211111 7.738 NM_198859
PRICKLE2
prickle homolog 2 (Drosophila)
chr1_+_164528586 7.691 NM_001204961
NM_001204963
NM_002585
PBX1


pre-B-cell leukemia homeobox 1


chr11_-_26593667 7.430 NM_001135091
NM_001135092
NM_145650
MUC15


mucin 15, cell surface associated


chr12_-_45269340 7.140 NM_001145109
NELL2
NEL-like 2 (chicken)
chr17_-_80797889 6.506 NM_024702
ZNF750
zinc finger protein 750
chr15_+_25101697 6.469 NM_022805
SNRPN
small nuclear ribonucleoprotein polypeptide N
chr9_+_17578952 6.407 NM_003026
SH3GL2
SH3-domain GRB2-like 2
chr1_+_201979689 6.403 NM_001114309
NM_004433
ELF3

E74-like factor 3 (ets domain transcription factor, epithelial-specific )

chr14_+_79745653 6.388 NM_001105250
NM_138970
NRXN3

neurexin 3

chr1_+_201979747 6.037 ELF3
E74-like factor 3 (ets domain transcription factor, epithelial-specific )
chr2_-_175712276 5.790 NM_001206602
CHN1
chimerin (chimaerin) 1
chr1_-_108507474 5.764 NM_006113
VAV3
vav 3 guanine nucleotide exchange factor
chr17_-_48072566 5.685 NM_005220
DLX3
distal-less homeobox 3
chr14_-_99737821 5.527 NM_022898
NM_138576
BCL11B

B-cell CLL/lymphoma 11B (zinc finger protein)

chr17_-_39675078 5.471 NM_002275
KRT15
keratin 15
chr2_+_237478379 5.417 NM_020311
CXCR7
chemokine (C-X-C motif) receptor 7
chr5_-_124080773 5.249 NM_020747
ZNF608
zinc finger protein 608
chr16_+_82660390 5.173 NM_001220488
NM_001220489
NM_001220490
NM_001220491
NM_001220492
NM_001257
CDH13





cadherin 13, H-cadherin (heart)





chr1_+_152730505 5.146 NM_001025231
KPRP
keratinocyte proline-rich protein
chr2_+_171034654 5.107 NM_001083615
NM_001171642
NM_138995
MYO3B


myosin IIIB


chr1_+_212782103 5.105 ATF3
activating transcription factor 3
chr11_-_94964209 5.062 NM_144665
SESN3
sestrin 3
chr4_-_153303663 4.961 NM_001013415
FBXW7
F-box and WD repeat domain containing 7
chr5_-_160279045 4.949 NM_025153
ATP10B
ATPase, class V, type 10B
chr1_+_66458389 4.922 NM_001037340
PDE4B
phosphodiesterase 4B, cAMP-specific
chr1_-_217263195 4.892 NM_001243505
ESRRG
estrogen-related receptor gamma
chr3_-_123603144 4.749 NM_053025
NM_053026
NM_053027
NM_053028
MYLK



myosin light chain kinase



chr8_+_75736771 4.681 NM_015886
PI15
peptidase inhibitor 15
chr18_-_56296188 4.659 NM_052947
ALPK2
alpha-kinase 2
chr5_+_53751430 4.575 NM_006308
HSPB3
heat shock 27kDa protein 3
chr6_-_26216871 4.566 NM_003518
HIST1H2BG
NCALD
histone cluster 1, H2bg
neurocalcin delta
chr15_+_25068793 4.479 NM_022806
NM_022807
NM_022808
SNRPN


small nuclear ribonucleoprotein polypeptide N


chr17_-_63557615 4.457 NM_004655
AXIN2
axin 2
chr16_+_82660641 4.405 CDH13
cadherin 13, H-cadherin (heart)
chr7_-_141673572 4.372 NM_176817
TAS2R38
taste receptor, type 2, member 38
chr17_+_7554415 4.367 ATP1B2
ATPase, Na+/K+ transporting, beta 2 polypeptide
chr16_+_82660573 4.334 CDH13
cadherin 13, H-cadherin (heart)
chrX_-_84634742 4.328 NM_024921
POF1B
premature ovarian failure, 1B
chr5_+_59784004 4.242 PART1
prostate androgen-regulated transcript 1 (non-protein coding)
chr5_-_134914968 4.235 NM_004887
CXCL14
chemokine (C-X-C motif) ligand 14
chr7_-_14029286 4.235 ETV1
ets variant 1
chr1_-_151345156 4.229 NM_003944
SELENBP1
selenium binding protein 1
chr22_+_22676814 4.225


chrX_-_84634664 4.177 POF1B
premature ovarian failure, 1B
chr6_+_136172802 4.144 NM_018945
PDE7B
phosphodiesterase 7B
chr4_+_184826427 4.048 NM_020225
STOX2
storkhead box 2
chr5_-_111091947 4.041 NM_001142483
C5orf13
chromosome 5 open reading frame 13
chr4_-_186733372 4.004 NM_003603
NM_001145670
SORBS2

sorbin and SH3 domain containing 2

chr2_+_17721983 3.903 VSNL1
visinin-like 1
chr5_-_111092918 3.864 NM_004772
C5orf13
chromosome 5 open reading frame 13
chr12_-_53207843 3.847 NM_002272
KRT4
keratin 4
chr2_+_166326156 3.847 NM_001172173
CSRNP3
cysteine-serine-rich nuclear protein 3
chr7_-_37024664 3.841 NM_001039459
ELMO1
engulfment and cell motility 1
chr2_+_17721806 3.804 NM_003385
VSNL1
visinin-like 1
chr6_+_135516879 3.793


chr10_-_94003002 3.773 NM_001178137
CPEB3
cytoplasmic polyadenylation element binding protein 3
chr14_+_62462540 3.762 NM_031914
SYT16
synaptotagmin XVI
chr2_-_167005641 3.762 NM_001202435
SCN1A
sodium channel, voltage-gated, type I, alpha subunit
chr1_-_196577438 3.752 NM_198503
KCNT2
potassium channel, subfamily T, member 2
chr11_+_65271145 3.750


chr13_-_61989209 3.742 PCDH20
protocadherin 20
chr15_+_48010685 3.722 NM_020858
NM_024966
NM_153616
NM_153617
NM_153618
NM_153619
SEMA6D





sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D





chr5_-_111092865 3.706 C5orf13
chromosome 5 open reading frame 13
chr7_+_129932973 3.700 NM_001163446
NM_016352
CPA4

carboxypeptidase A4

chr2_-_239197091 3.660 NM_022817
PER2
period homolog 2 (Drosophila)
chr13_+_97999289 3.646


chr5_-_24645084 3.631 NM_006727
CDH10
cadherin 10, type 2 (T2-cadherin)
chr1_-_196577676 3.603 KCNT2
potassium channel, subfamily T, member 2
chr3_+_181430075 3.549 SOX2
SRY (sex determining region Y)-box 2
chr10_+_77542518 3.537 NM_032024
C10orf11
chromosome 10 open reading frame 11
chr5_+_36608430 3.506 NM_001166695
SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr1_-_217262946 3.488 NM_001243506
NM_206594
NM_206595
ESRRG


estrogen-related receptor gamma


chr6_+_106546736 3.483 NM_182907
PRDM1
PR domain containing 1, with ZNF domain
chr12_+_14518608 3.458 NM_018179
ATF7IP
activating transcription factor 7 interacting protein
chr11_-_56310732 3.437 NM_001005245
OR5M11
olfactory receptor, family 5, subfamily M, member 11
chr17_-_36105005 3.409 NM_000458
NM_001165923
HNF1B

HNF1 homeobox B

chr5_-_134914447 3.399 CXCL14
chemokine (C-X-C motif) ligand 14
chr3_+_25470067 3.382 RARB
retinoic acid receptor, beta
chr14_-_106733392 3.363 IGHG1
IGHG3
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 3 (G3m marker)
chr5_-_111312522 3.361 NM_001142474
NM_001142475
C5orf13

chromosome 5 open reading frame 13

chr5_+_147443534 3.357 NM_001127698
NM_001127699
NM_006846
SPINK5


serine peptidase inhibitor, Kazal type 5


chr6_-_108145507 3.339 NM_198081
SCML4
sex comb on midleg-like 4 (Drosophila)
chr21_-_31588242 3.319 NM_199328
CLDN8
claudin 8
chr1_+_153003677 3.309 NM_003125
SPRR1B
small proline-rich protein 1B
chr3_+_181429711 3.305 NM_003106
SOX2
SRY (sex determining region Y)-box 2
chr9_-_95298251 3.302 NM_001197295
NM_001197296
NM_001393
ECM2


extracellular matrix protein 2, female organ and adipocyte specific


chr1_+_212781969 3.290 NM_001040619
NM_001206484
NM_001206488
NM_001674
ATF3



activating transcription factor 3



chr17_-_8815799 3.279 NM_014308
PIK3R5
phosphoinositide-3-kinase, regulatory subunit 5
chr12_+_107712151 3.252 NM_001018072
BTBD11
BTB (POZ) domain containing 11
chr17_-_36104874 3.249 HNF1B
HNF1 homeobox B
chr7_+_22766765 3.247 NM_000600
IL6
interleukin 6 (interferon, beta 2)
chr15_-_83240499 3.201 NM_001079533
NM_001079534
NM_001079535
CPEB1


cytoplasmic polyadenylation element binding protein 1


chr13_-_86373328 3.196 NM_032229
SLITRK6
SLIT and NTRK-like family, member 6
chr4_+_70796798 3.190 NM_001025104
NM_001890
CSN1S1

casein alpha s1

chrX_+_109662284 3.173 NM_020769
RGAG1
retrotransposon gag domain containing 1
chr1_+_116654375 3.139 NM_152367
MAB21L3
mab-21-like 3 (C. elegans)
chr2_-_217540722 3.133 IGFBP5
insulin-like growth factor binding protein 5
chr4_-_110223798 3.130 NM_032518
NM_198721
COL25A1

collagen, type XXV, alpha 1

chr6_-_154651214 3.129 NM_001130699
IPCEF1
interaction protein for cytohesin exchange factors 1
chr16_-_48269087 3.099 NM_032583
NM_145186
ABCC11

ATP-binding cassette, sub-family C (CFTR/MRP), member 11

chr4_+_134070443 3.092 NM_020815
NM_032961
PCDH10

protocadherin 10

chr1_-_20306908 3.087 NM_000300
NM_001161727
NM_001161728
PLA2G2A


phospholipase A2, group IIA (platelets, synovial fluid)


chr19_-_18314731 3.078 NM_002866
RAB3A
RAB3A, member RAS oncogene family
chr12_-_81763127 3.074 NM_001220479
NM_001220480
PPFIA2

protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2

chr1_-_153348057 3.039 NM_005621
S100A12
S100 calcium binding protein A12
chr2_-_228582698 3.038 NM_025243
SLC19A3
solute carrier family 19, member 3
chr17_+_7554239 2.976 NM_001678
ATP1B2
ATPase, Na+/K+ transporting, beta 2 polypeptide
chr1_-_177133950 2.935 NM_004319
NM_207108
ASTN1

astrotactin 1

chr19_-_51587466 2.926 NM_022046
KLK14
kallikrein-related peptidase 14
chr13_-_103054027 2.901 NM_175929
FGF14
fibroblast growth factor 14
chr4_-_153273683 2.893 NM_018315
FBXW7
F-box and WD repeat domain containing 7
chr7_-_126883568 2.883 NM_000845
GRM8
glutamate receptor, metabotropic 8
chr6_-_134497069 2.869 NM_001143678
SGK1
serum/glucocorticoid regulated kinase 1
chr1_+_17575592 2.855 NM_016233
PADI3
peptidyl arginine deiminase, type III
chr11_-_3663484 2.850 NM_053017
NM_001079536
ART5

ADP-ribosyltransferase 5

chr10_+_11206928 2.850 NM_001025076
NM_001083591
CELF2

CUGBP, Elav-like family member 2

chr1_+_33722158 2.837 NM_152493
ZNF362
zinc finger protein 362
chr9_-_75567915 2.828 ALDH1A1
aldehyde dehydrogenase 1 family, member A1
chr12_-_122240827 2.827


chr14_-_99737554 2.825 BCL11B
B-cell CLL/lymphoma 11B (zinc finger protein)
chr12_+_109551041 2.815


chr20_+_56136136 2.789 NM_002591
PCK1
phosphoenolpyruvate carboxykinase 1 (soluble)
chr22_-_24096551 2.786 NM_013378
VPREB3
pre-B lymphocyte 3
chr6_+_135517051 2.782 MYB
v-myb myeloblastosis viral oncogene homolog (avian)
chr2_+_189839113 2.775 COL3A1
collagen, type III, alpha 1
chr9_-_124990706 2.746 NM_001242333
LHX6
LIM homeobox 6
chr6_-_26043884 2.728 NM_021062
HIST1H2BB
histone cluster 1, H2bb
chr7_+_48211054 2.726 NM_152701
ABCA13
ATP-binding cassette, sub-family A (ABC1), member 13
chr6_-_134498973 2.707 NM_001143677
SGK1
serum/glucocorticoid regulated kinase 1
chr14_+_65007418 2.696 HSPA2
heat shock 70kDa protein 2
chr12_-_123187842 2.694 NM_177551
HCAR2
hydroxycarboxylic acid receptor 2
chrX_+_9431314 2.690 NM_001139466
NM_001139467
NM_001139468
TBL1X


transducin (beta)-like 1X-linked


chr1_+_248128534 2.687 NM_001004491
OR2AK2
olfactory receptor, family 2, subfamily AK, member 2
chr20_+_17207680 2.658 PCSK2
proprotein convertase subtilisin/kexin type 2
chr20_-_7921068 2.654 NM_017545
HAO1
hydroxyacid oxidase (glycolate oxidase) 1
chr7_+_143140545 2.650 NM_177437
TAS2R60
taste receptor, type 2, member 60
chrX_-_80457440 2.645 NM_030763
HMGN5
high mobility group nucleosome binding domain 5
chr15_-_72612497 2.616 NM_052840
CELF6
CUGBP, Elav-like family member 6
chr2_+_233734993 2.614 NM_206895
C2orf82
chromosome 2 open reading frame 82
chr3_+_48264836 2.596 NM_004345
CAMP
cathelicidin antimicrobial peptide
chr6_+_26273143 2.592 NM_003525
HIST1H2BI
histone cluster 1, H2bi
chr10_-_61122219 2.587 NM_001001971
NM_001166698
NM_198215
FAM13C


family with sequence similarity 13, member C


chr3_+_46395224 2.584 NM_001123041
NM_001123396
CCR2

chemokine (C-C motif) receptor 2

chr14_-_106877689 2.551 IGHV4-31
IGH@
IGHA1
IGHA2
IGHG1
IGHG4
IGHM
immunoglobulin heavy variable 4-31
immunoglobulin heavy locus
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant alpha 2 (A2m marker)
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 4 (G4m marker)
immunoglobulin heavy constant mu
chr6_+_47624222 2.547 NM_153839
GPR111
G protein-coupled receptor 111
chr6_-_26124130 2.543 NM_003526
HIST1H2BG
HIST1H2BC
histone cluster 1, H2bg
histone cluster 1, H2bc
chr22_-_45405780 2.526 NM_001135862
PHF21B
PHD finger protein 21B
chr15_-_72612469 2.522 CELF6
CUGBP, Elav-like family member 6
chr20_+_306205 2.521 NM_006943
SOX12
SRY (sex determining region Y)-box 12
chr3_+_134514044 2.520 NM_004441
EPHB1
EPH receptor B1
chr4_+_158141735 2.513 NM_000826
NM_001083619
NM_001083620
GRIA2


glutamate receptor, ionotropic, AMPA 2


chr7_-_14029641 2.495 NM_001163147
NM_004956
ETV1

ets variant 1

chr3_-_193272587 2.492 NM_032279
ATP13A4
ATPase type 13A4
chr8_-_93111915 2.485 NM_001198628
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr7_-_27183225 2.480 NM_019102
HOXA5
homeobox A5
chr7_+_107110501 2.462 NM_005295
GPR22
G protein-coupled receptor 22
chr12_+_93096618 2.455 NM_001037671
NM_001178097
C12orf74

chromosome 12 open reading frame 74

chr3_-_99833348 2.447 NM_001042459
NM_182909
FILIP1L

filamin A interacting protein 1-like

chr20_+_17207669 2.430 PCSK2
proprotein convertase subtilisin/kexin type 2
chr3_+_134514300 2.421 EPHB1
EPH receptor B1
chr10_+_11207053 2.407 CELF2
CUGBP, Elav-like family member 2
chr7_+_141463896 2.402 NM_016943
TAS2R3
taste receptor, type 2, member 3
chr3_+_127641901 2.388 NM_207335
KBTBD12
kelch repeat and BTB (POZ) domain containing 12
chr18_+_31158540 2.381 NM_030632
ASXL3
additional sex combs like 3 (Drosophila)
chr7_-_82791799 2.377 PCLO
piccolo (presynaptic cytomatrix protein)
chr17_-_46655544 2.348 NM_024015
HOXB4
homeobox B4
chr5_-_146257633 2.307 PPP2R2B
protein phosphatase 2, regulatory subunit B, beta
chr11_-_115375065 2.306 NM_001098517
NM_014333
CADM1

cell adhesion molecule 1

chr2_+_189839132 2.306 COL3A1
collagen, type III, alpha 1
chr12_-_57328044 2.305 NM_148897
SDR9C7
short chain dehydrogenase/reductase family 9C, member 7
chr9_-_124990949 2.301 NM_014368
NM_199160
LHX6

LIM homeobox 6

chr11_-_118047336 2.298 NM_004588
SCN2B
sodium channel, voltage-gated, type II, beta
chr7_+_80267972 2.291 CD36
CD36 molecule (thrombospondin receptor)
chr1_-_177134042 2.290 ASTN1
astrotactin 1
chr6_-_149806025 2.288 ZC3H12D
zinc finger CCCH-type containing 12D
chr7_-_76829109 2.281 NM_006682
FGL2
fibrinogen-like 2
chrX_-_24665454 2.277 NM_001163265
NM_004845
PCYT1B

phosphate cytidylyltransferase 1, choline, beta

chr17_+_41052813 2.275 NM_000151
G6PC
glucose-6-phosphatase, catalytic subunit
chr19_+_14693895 2.270 NM_001204118
NM_207390
CLEC17A

C-type lectin domain family 17, member A

chr4_+_41258941 2.263 UCHL1
ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
chr5_-_88179278 2.261 NM_001193350
NM_002397
MEF2C

myocyte enhancer factor 2C

chr1_-_193155723 2.253 NM_003783
B3GALT2
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
chr17_-_37381920 2.253 NM_198993
STAC2
SH3 and cysteine rich domain 2
chr18_+_61254533 2.251 NM_012397
SERPINB13
serpin peptidase inhibitor, clade B (ovalbumin), member 13
chr3_+_188889762 2.248 NM_198485
TPRG1
tumor protein p63 regulated 1
chr2_-_166060552 2.244 NM_001081676
NM_001081677
NM_006922
SCN3A


sodium channel, voltage-gated, type III, alpha subunit


chr5_-_95748688 2.238 NM_001177876
PCSK1
proprotein convertase subtilisin/kexin type 1
chr12_-_45269953 2.230 NELL2
NEL-like 2 (chicken)
chr15_-_72612127 2.227 CELF6
CUGBP, Elav-like family member 6

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
1.54 1.27e-10 GO:0032501 multicellular organismal process
1.69 7.27e-07 GO:0048731 system development
1.64 1.09e-06 GO:0048856 anatomical structure development
1.58 2.86e-06 GO:0007275 multicellular organismal development
9.30 5.06e-06 GO:0050909 sensory perception of taste
1.53 8.60e-06 GO:0032502 developmental process
2.52 1.42e-05 GO:0010628 positive regulation of gene expression
1.81 1.72e-05 GO:0048513 organ development
1.77 2.26e-05 GO:0030154 cell differentiation
2.38 2.74e-05 GO:0007267 cell-cell signaling
2.16 3.03e-05 GO:0007154 cell communication
1.72 8.81e-05 GO:0048869 cellular developmental process
1.89 9.91e-05 GO:0007399 nervous system development
2.68 1.38e-04 GO:0019226 transmission of nerve impulse
2.68 1.38e-04 GO:0035637 multicellular organismal signaling
2.43 2.45e-04 GO:0045893 positive regulation of transcription, DNA-dependent
2.08 3.22e-04 GO:0006357 regulation of transcription from RNA polymerase II promoter
2.63 4.91e-04 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
1.86 6.63e-04 GO:0050877 neurological system process
2.67 7.66e-04 GO:0007268 synaptic transmission
1.31 9.20e-04 GO:0050896 response to stimulus
2.10 1.21e-03 GO:0009888 tissue development
2.27 1.56e-03 GO:0051254 positive regulation of RNA metabolic process
2.18 1.71e-03 GO:0010557 positive regulation of macromolecule biosynthetic process
3.20 4.74e-03 GO:0048568 embryonic organ development
2.87 6.41e-03 GO:0016337 cell-cell adhesion
2.10 6.48e-03 GO:0007155 cell adhesion
2.10 6.48e-03 GO:0022610 biological adhesion
2.10 6.48e-03 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.41 7.54e-03 GO:0023052 signaling
2.59 1.07e-02 GO:0060429 epithelium development
2.06 1.35e-02 GO:0006955 immune response
2.03 1.38e-02 GO:0051173 positive regulation of nitrogen compound metabolic process
1.98 1.58e-02 GO:0031328 positive regulation of cellular biosynthetic process
3.15 1.72e-02 GO:0043193 positive regulation of gene-specific transcription
2.43 1.74e-02 GO:0032583 regulation of gene-specific transcription
1.64 1.88e-02 GO:0003008 system process
1.95 2.42e-02 GO:0009891 positive regulation of biosynthetic process
1.80 2.46e-02 GO:0010604 positive regulation of macromolecule metabolic process
1.89 3.38e-02 GO:0048468 cell development
3.24 3.51e-02 GO:0030855 epithelial cell differentiation
1.74 3.84e-02 GO:0009893 positive regulation of metabolic process

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
1.64 8.29e-05 GO:0044459 plasma membrane part
1.39 3.23e-04 GO:0071944 cell periphery
1.39 3.43e-04 GO:0005886 plasma membrane
3.37 9.22e-04 GO:0030425 dendrite
2.49 1.51e-03 GO:0045202 synapse
2.78 1.57e-03 GO:0044456 synapse part
2.44 3.28e-03 GO:0043005 neuron projection
13.88 3.70e-03 GO:0001518 voltage-gated sodium channel complex
1.52 9.48e-03 GO:0005576 extracellular region
11.10 1.30e-02 GO:0034706 sodium channel complex
1.67 1.72e-02 GO:0031226 intrinsic to plasma membrane
1.67 1.90e-02 GO:0005887 integral to plasma membrane

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
2.44 5.62e-06 GO:0043565 sequence-specific DNA binding
2.12 1.32e-05 GO:0001071 nucleic acid binding transcription factor activity
2.12 1.32e-05 GO:0003700 sequence-specific DNA binding transcription factor activity
8.33 7.00e-05 GO:0003823 antigen binding
13.33 9.66e-04 GO:0008527 taste receptor activity
1.67 1.24e-03 GO:0004872 receptor activity
19.03 8.96e-03 GO:0042043 neurexin binding
5.45 1.17e-02 GO:0042562 hormone binding
1.52 1.27e-02 GO:0004871 signal transducer activity
1.52 1.27e-02 GO:0060089 molecular transducer activity
11.90 1.31e-02 GO:0005248 voltage-gated sodium channel activity
1.75 2.82e-02 GO:0030528 transcription regulator activity
5.23 4.36e-02 GO:0003707 steroid hormone receptor activity