Motif ID: POU3F1..4.p2

Z-value: 0.661


Transcription factors associated with POU3F1..4.p2:

Gene SymbolEntrez IDGene Name
POU3F1 5453 POU class 3 homeobox 1
POU3F2 5454 POU class 3 homeobox 2
POU3F3 5455 POU class 3 homeobox 3
POU3F4 5456 POU class 3 homeobox 4

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
POU3F2hg19_v1_chr6_+_99282579_992825820.561.4e-07Click!
POU3F3hg19_v1_chr2_+_105471745_1054720510.403.9e-04Click!
POU3F1hg19_v1_chr1_-_38512446_385124530.371.1e-03Click!


Activity profile for motif POU3F1..4.p2.

activity profile for motif POU3F1..4.p2


Sorted Z-values histogram for motif POU3F1..4.p2

Sorted Z-values for motif POU3F1..4.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of POU3F1..4.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_-_83278478 4.382 NM_012431
SEMA3E
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
chr2_+_166428845 2.507 NM_024969
CSRNP3
cysteine-serine-rich nuclear protein 3
chr18_+_61442611 2.438 NM_003784
SERPINB7
serpin peptidase inhibitor, clade B (ovalbumin), member 7
chr1_+_152956563 2.347 NM_001199828
NM_005987
SPRR1A

small proline-rich protein 1A

chr7_-_83270746 2.299 NM_001178129
SEMA3E
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
chr2_-_113810439 2.252 NM_014438
NM_173178
IL36B

interleukin 36, beta

chrX_+_65384078 2.157 NM_001130860
NM_014799
HEPH

hephaestin

chr3_-_99594915 2.104 NM_014890
FILIP1L
filamin A interacting protein 1-like
chr7_-_20256942 2.090 NM_182762
MACC1
metastasis associated in colon cancer 1
chr7_+_28338939 2.081 NM_182899
CREB5
cAMP responsive element binding protein 5
chr13_+_53602829 2.026 NM_006418
OLFM4
olfactomedin 4
chr3_+_108541544 2.022 NM_016388
TRAT1
T cell receptor associated transmembrane adaptor 1
chr15_+_25101697 2.022 NM_022805
SNRPN
small nuclear ribonucleoprotein polypeptide N
chr5_+_147582338 1.987 NM_001195290
NM_205841
SPINK6

serine peptidase inhibitor, Kazal type 6

chr12_+_100897137 1.914 NM_001206992
NM_001206993
NR1H4

nuclear receptor subfamily 1, group H, member 4

chr12_+_80603232 1.874 NM_173591
OTOGL
otogelin-like
chr6_-_114384008 1.855 NM_153612
HS3ST5
heparan sulfate (glucosamine) 3-O-sulfotransferase 5
chr4_-_69111333 1.830 NM_182502
TMPRSS11B
transmembrane protease, serine 11B
chr19_+_58180302 1.825 NM_152677
ZSCAN4
zinc finger and SCAN domain containing 4
chr20_-_9819406 1.818 NM_020341
NM_177990
PAK7

p21 protein (Cdc42/Rac)-activated kinase 7

chr1_-_156399183 1.805 NM_006365
C1orf61
chromosome 1 open reading frame 61
chr19_-_37663567 1.739 NM_152655
ZNF585A
zinc finger protein 585A
chr13_-_49110117 1.705 RCBTB2
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
chr11_+_105480799 1.700 NM_000829
NM_001077243
NM_001077244
GRIA4


glutamate receptor, ionotrophic, AMPA 4


chr6_-_152702329 1.689 SYNE1
spectrin repeat containing, nuclear envelope 1
chr7_-_132333446 1.664 NM_181775
PLXNA4
plexin A4
chr15_+_78384926 1.637 NM_001101404
SH2D7
SH2 domain containing 7
chr6_-_46889620 1.625 NM_001098518
GPR116
G protein-coupled receptor 116
chr6_+_46761093 1.620 NM_005588
MEP1A
meprin A, alpha (PABA peptide hydrolase)
chr5_+_40909617 1.601 C7
complement component 7
chr10_-_69425356 1.549 NM_001127384
CTNNA3
catenin (cadherin-associated protein), alpha 3
chr3_-_193272587 1.540 NM_032279
ATP13A4
ATPase type 13A4
chr1_+_247751661 1.538 NM_001001915
OR2G2
olfactory receptor, family 2, subfamily G, member 2
chr6_+_24357130 1.536 NM_181337
KAAG1
kidney associated antigen 1
chr18_+_67068134 1.526 NM_152721
DOK6
docking protein 6
chr1_+_66798095 1.525 PDE4B
phosphodiesterase 4B, cAMP-specific
chr5_+_55149149 1.513 NM_001242636
NM_001242639
IL31RA

interleukin 31 receptor A

chr5_-_157002739 1.510 NM_033274
ADAM19
ADAM metallopeptidase domain 19
chr5_+_40909558 1.493 NM_000587
C7
complement component 7
chr1_-_173020011 1.466 NM_005092
TNFSF18
tumor necrosis factor (ligand) superfamily, member 18
chr5_+_68788118 1.454 NM_002538
OCLN
occludin
chrX_-_135749436 1.428 ARHGEF6
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr21_-_34185943 1.418 NM_001162495
NM_001162496
NM_019596
C21orf62


chromosome 21 open reading frame 62


chr1_-_110933635 1.409 SLC16A4
solute carrier family 16, member 4 (monocarboxylic acid transporter 5)
chr1_-_89641722 1.407 NM_207398
GBP7
guanylate binding protein 7
chr6_-_132967141 1.397 NM_138327
TAAR1
trace amine associated receptor 1
chr7_+_57509882 1.390 NM_001159279
ZNF716
zinc finger protein 716
chr5_-_146460991 1.363 NM_181677
NM_181678
PPP2R2B

protein phosphatase 2, regulatory subunit B, beta

chr19_+_51358170 1.361 NM_001030047
NM_001030048
NM_001030050
NM_001648
KLK3



kallikrein-related peptidase 3



chr1_+_50575465 1.316 ELAVL4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chrX_+_47867169 1.310 NM_001079900
SPACA5
SPACA5B
sperm acrosome associated 5
sperm acrosome associated 5B
chr5_-_41213513 1.298 NM_000065
C6
complement component 6
chr9_-_22009270 1.262 NM_004936
NM_078487
CDKN2B

cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)

chr6_-_152702450 1.236 SYNE1
spectrin repeat containing, nuclear envelope 1
chr1_+_241815579 1.223 NM_144625
WDR64
WD repeat domain 64
chr4_+_74270832 1.220 ALB
albumin
chr4_-_100242487 1.215 NM_000668
ADH1A
ADH1B
alcohol dehydrogenase 1A (class I), alpha polypeptide
alcohol dehydrogenase 1B (class I), beta polypeptide
chr5_+_140474198 1.197 NM_018936
PCDHB2
protocadherin beta 2
chr16_+_6823809 1.175 NM_001142334
RBFOX1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr12_-_16759733 1.172 NM_001243610
LMO3
LIM domain only 3 (rhombotin-like 2)
chrX_+_48114796 1.170 NM_005635
SSX1
synovial sarcoma, X breakpoint 1
chr7_+_20655244 1.151 NM_001163941
ABCB5
ATP-binding cassette, sub-family B (MDR/TAP), member 5
chrX_+_100805415 1.141 NM_016608
ARMCX1
armadillo repeat containing, X-linked 1
chr6_-_32977312 1.133 HLA-DOA
major histocompatibility complex, class II, DO alpha
chr12_+_93096618 1.131 NM_001037671
NM_001178097
C12orf74

chromosome 12 open reading frame 74

chr1_+_117297056 1.103 NM_001767
CD2
CD2 molecule
chr6_+_47624222 1.103 NM_153839
GPR111
G protein-coupled receptor 111
chr12_-_16759939 1.076 NM_001243613
LMO3
LIM domain only 3 (rhombotin-like 2)
chr9_+_131684561 1.072 NM_001100877
PHYHD1
phytanoyl-CoA dioxygenase domain containing 1
chr11_+_113775517 1.062 NM_006028
HTR3B
5-hydroxytryptamine (serotonin) receptor 3B
chrX_+_91089658 1.050 NM_014522
NM_032968
NM_032969
PCDH11X


protocadherin 11 X-linked


chr9_+_117904096 1.047 NM_017418
DEC1
deleted in esophageal cancer 1
chr19_+_16830786 1.040 NM_001007525
NWD1
NACHT and WD repeat domain containing 1
chr19_-_54804172 1.040 NM_001172654
NM_006865
LILRA3

LILRA6
leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3

leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6
chr10_-_52008312 1.032 NM_001143974
NM_019893
ASAH2

N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2

chr2_-_77749335 1.029 NM_001134745
NM_024993
LRRTM4

leucine rich repeat transmembrane neuronal 4

chr11_-_58499368 1.024 NM_005838
NM_201648
GLYAT

glycine-N-acyltransferase

chr7_+_141463896 1.018 NM_016943
TAS2R3
taste receptor, type 2, member 3
chr18_+_61575203 1.012 SERPINB10
serpin peptidase inhibitor, clade B (ovalbumin), member 10
chr8_+_1993157 1.005 NM_003970
MYOM2
myomesin (M-protein) 2, 165kDa
chr4_+_187148624 1.003 NM_000892
KLKB1
kallikrein B, plasma (Fletcher factor) 1
chr2_-_163008913 1.002 NM_002054
GCG
glucagon
chr2_+_68961912 1.002 NM_001007231
NM_001166277
ARHGAP25

Rho GTPase activating protein 25

chr1_+_171283372 0.991 NM_002022
FMO4
flavin containing monooxygenase 4
chr2_+_68872953 0.987 NM_138964
PROKR1
prokineticin receptor 1
chr12_+_52056547 0.975 NM_001177984
SCN8A
sodium channel, voltage gated, type VIII, alpha subunit
chr1_+_171060017 0.958 NM_001002294
NM_006894
FMO3

flavin containing monooxygenase 3

chr9_-_19786886 0.952 NM_001193288
NM_020344
SLC24A2

solute carrier family 24 (sodium/potassium/calcium exchanger), member 2

chr9_-_107367907 0.951 NM_001004481
OR13C2
olfactory receptor, family 13, subfamily C, member 2
chr15_+_25068793 0.946 NM_022806
NM_022807
NM_022808
SNRPN


small nuclear ribonucleoprotein polypeptide N


chr3_+_11267666 0.946 NM_001098211
HRH1
histamine receptor H1
chr18_-_48346297 0.945 NM_001127175
NM_001127176
NM_031939
MRO


maestro


chr1_-_68915631 0.945 NM_000329
RPE65
retinal pigment epithelium-specific protein 65kDa
chr6_-_32977351 0.938 NM_002119
HLA-DOA
major histocompatibility complex, class II, DO alpha
chr18_-_3845295 0.930 NM_001003809
NM_001242765
NM_001242766
DLGAP1


discs, large (Drosophila) homolog-associated protein 1


chr5_-_157002705 0.924


chr12_+_21525801 0.917 NM_000415
IAPP
islet amyloid polypeptide
chrX_+_88002225 0.914 NM_001184771
NM_033048
CPXCR1

CPX chromosome region, candidate 1

chr3_+_121613170 0.905 NM_001145998
NM_021082
SLC15A2

solute carrier family 15 (H+/peptide transporter), member 2

chr7_-_16921596 0.902 NM_176813
AGR3
anterior gradient 3 homolog (Xenopus laevis)
chr7_+_29519485 0.900 NM_001039936
CHN2
chimerin (chimaerin) 2
chr13_-_61989209 0.895 PCDH20
protocadherin 20
chr3_+_25469833 0.885 NM_000965
RARB
retinoic acid receptor, beta
chr1_-_154178783 0.877 NM_001010979
C1orf189
chromosome 1 open reading frame 189
chr4_+_74269971 0.873 NM_000477
ALB
albumin
chr13_-_36429798 0.861 NM_001195415
NM_001195416
NM_001195430
DCLK1


doublecortin-like kinase 1


chr3_-_151102536 0.859 NM_022788
P2RY12
purinergic receptor P2Y, G-protein coupled, 12
chr6_-_139613114 0.857 NM_153235
TXLNB
taxilin beta
chr2_+_191014971 0.849 NM_001042520
C2orf88
chromosome 2 open reading frame 88
chr9_-_111618209 0.847 NM_006686
ACTL7B
actin-like 7B
chr18_+_59157774 0.846 NM_031891
CDH20
cadherin 20, type 2
chr4_-_44653657 0.843 NM_182592
YIPF7
Yip1 domain family, member 7
chr6_+_121756744 0.838 NM_000165
GJA1
gap junction protein, alpha 1, 43kDa
chr4_+_68424444 0.833 NM_012108
STAP1
signal transducing adaptor family member 1
chr19_+_55128601 0.816 NM_006669
LILRB1
leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1
chr13_+_113633625 0.812 MCF2L
MCF.2 cell line derived transforming sequence-like
chr5_-_147211141 0.802 SPINK1
serine peptidase inhibitor, Kazal type 1
chr1_-_157811491 0.799 NM_005894
CD5L
CD5 molecule-like
chr3_-_124653571 0.799 NM_033049
MUC13
mucin 13, cell surface associated
chr11_-_8954534 0.794 NM_020643
C11orf16
chromosome 11 open reading frame 16
chr2_+_189839113 0.793 COL3A1
collagen, type III, alpha 1
chr7_-_107443631 0.793 NM_000111
SLC26A3
solute carrier family 26, member 3
chr14_-_106471439 0.792 IGHA1
IGHG1
IGHM
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant mu
chr7_-_87342569 0.790 NM_000927
ABCB1
ATP-binding cassette, sub-family B (MDR/TAP), member 1
chr12_+_21168629 0.780 NM_001009562
SLCO1B7
solute carrier organic anion transporter family, member 1B7 (non-functional)
chrX_-_137821514 0.768 NM_033642
FGF13
fibroblast growth factor 13
chr10_+_65224937 0.768 LOC84989
uncharacterized LOC84989
chr7_+_106505696 0.765 PIK3CG
phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr5_+_54398473 0.764 NM_006144
GZMA
granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)
chr12_-_95945226 0.760 NM_032147
USP44
ubiquitin specific peptidase 44
chr3_+_169629359 0.758 NM_182610
SAMD7
sterile alpha motif domain containing 7
chr3_-_147122070 0.756 NM_001168378
ZIC4
Zic family member 4
chr19_-_48389514 0.754 SULT2A1
sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1
chr8_-_124749573 0.754 NM_001003954
NM_004306
ANXA13

annexin A13

chr3_+_75713480 0.753 NM_001124759
FRG2C
FLJ20518
FSHD region gene 2 family, member C
FSHD region gene 2 family, member C pseudogene
chr7_-_126883568 0.742 NM_000845
GRM8
glutamate receptor, metabotropic 8
chrX_+_67913479 0.738 NM_001142504
STARD8
StAR-related lipid transfer (START) domain containing 8
chr4_+_102711833 0.735 BANK1
B-cell scaffold protein with ankyrin repeats 1
chr16_-_53405040 0.732 NM_001207030
LOC643802
u3 small nucleolar ribonucleoprotein protein MPP10-like
chr1_+_244515936 0.732 NM_001012970
C1orf100
chromosome 1 open reading frame 100
chrX_+_47990038 0.728 NM_001079900
SPACA5
SPACA5B
sperm acrosome associated 5
sperm acrosome associated 5B
chr12_+_52281743 0.727 NM_001130015
NM_182608
ANKRD33

ankyrin repeat domain 33

chr7_+_28475233 0.724 NM_004904
CREB5
cAMP responsive element binding protein 5
chr2_-_231989755 0.722 NM_000867
HTR2B
5-hydroxytryptamine (serotonin) receptor 2B
chr18_-_56296188 0.721 NM_052947
ALPK2
alpha-kinase 2
chr21_-_39956823 0.719 NM_001243429
ERG
v-ets erythroblastosis virus E26 oncogene homolog (avian)
chr2_+_135596185 0.717 NM_138326
ACMSD
aminocarboxymuconate semialdehyde decarboxylase
chr2_+_166095911 0.717 NM_001040142
SCN2A
sodium channel, voltage-gated, type II, alpha subunit
chr3_+_151591428 0.700 NM_033050
SUCNR1
succinate receptor 1
chr7_-_99381703 0.697 NM_001202855
NM_017460
CYP3A4

cytochrome P450, family 3, subfamily A, polypeptide 4

chr10_+_114043413 0.693 NM_058222
TECTB
tectorin beta
chr19_-_51587466 0.692 NM_022046
KLK14
kallikrein-related peptidase 14
chr4_+_88720701 0.690 NM_004967
IBSP
integrin-binding sialoprotein
chr8_+_75736771 0.688 NM_015886
PI15
peptidase inhibitor 15
chr6_+_27925018 0.677 NM_012367
OR2B6
olfactory receptor, family 2, subfamily B, member 6
chr3_-_74570262 0.677 NM_020872
CNTN3
contactin 3 (plasmacytoma associated)
chr7_+_106505739 0.670 PIK3CG
phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr2_+_1418179 0.665 NM_175721
NM_175722
TPO

thyroid peroxidase

chr17_+_39555993 0.659 GAST
gastrin
chr7_+_26438186 0.657 LOC441204
uncharacterized LOC441204
chr1_-_144997110 0.656 NM_001195260
PDE4DIP
phosphodiesterase 4D interacting protein
chr17_+_4675175 0.650 NM_003963
TM4SF5
transmembrane 4 L six family member 5
chr18_+_43306917 0.642 NM_001146037
SLC14A1
solute carrier family 14 (urea transporter), member 1 (Kidd blood group)
chrX_+_125953746 0.641 NM_001122716
CXorf64
chromosome X open reading frame 64
chr19_-_48389571 0.636 NM_003167
SULT2A1
sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1
chr5_+_161275897 0.632 NM_001127646
GABRA1
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr1_+_12851545 0.629 NM_023013
PRAMEF1
PRAME family member 1
chr12_+_8975149 0.625 NM_144670
A2ML1
alpha-2-macroglobulin-like 1
chr18_+_54814292 0.622 BOD1P
biorientation of chromosomes in cell division 1 pseudogene
chr1_-_182922504 0.620 NM_030933
SHCBP1L
SHC SH2-domain binding protein 1-like
chr17_+_68071386 0.619 NM_018658
NM_170741
KCNJ16

potassium inwardly-rectifying channel, subfamily J, member 16

chr2_-_100722328 0.616 AFF3
AF4/FMR2 family, member 3
chr5_+_147258273 0.613 NM_054023
SCGB3A2
secretoglobin, family 3A, member 2
chr5_-_142000899 0.610 NM_001144892
FGF1
fibroblast growth factor 1 (acidic)
chr17_+_32582295 0.610 NM_002982
CCL2
chemokine (C-C motif) ligand 2
chr7_-_84751246 0.606 NM_152754
SEMA3D
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D
chr10_+_29577989 0.605 NM_032517
LYZL1
lysozyme-like 1
chr8_-_95229530 0.593 NM_001144663
CDH17
cadherin 17, LI cadherin (liver-intestine)
chr7_+_129847699 0.592 NM_145268
C7orf45
chromosome 7 open reading frame 45
chr10_-_16564003 0.591 NM_001010908
C1QL3
complement component 1, q subcomponent-like 3
chr12_+_12224401 0.589 NM_030766
NM_138722
BCL2L14

BCL2-like 14 (apoptosis facilitator)

chr7_-_122839999 0.588 NM_022444
SLC13A1
solute carrier family 13 (sodium/sulfate symporters), member 1
chr9_-_75568232 0.582 NM_000689
ALDH1A1
aldehyde dehydrogenase 1 family, member A1
chr3_+_63638343 0.576 NM_001080537
SNTN
sentan, cilia apical structure protein
chr16_-_90128591 0.576 NM_052996
PRDM7
PR domain containing 7
chr5_-_169724614 0.574 LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr6_+_144185572 0.574 NM_001013623
C6orf94
chromosome 6 open reading frame 94
chr9_+_35042222 0.571 NM_001040410
NM_203299
C9orf131

chromosome 9 open reading frame 131

chr18_-_45663667 0.568 NM_001039360
ZBTB7C
zinc finger and BTB domain containing 7C
chr4_+_102711763 0.567 NM_001127507
NM_017935
BANK1

B-cell scaffold protein with ankyrin repeats 1

chr21_-_33957746 0.566 NM_144659
TCP10L
t-complex 10 (mouse)-like
chrX_-_48327739 0.566 SLC38A5
solute carrier family 38, member 5
chr20_+_16728997 0.565 NM_020157
OTOR
otoraplin
chr17_-_64225496 0.563 NM_000042
APOH
apolipoprotein H (beta-2-glycoprotein I)
chr6_-_117150197 0.562 NM_148963
GPRC6A
G protein-coupled receptor, family C, group 6, member A
chr1_+_110993748 0.561 NM_032414
PROK1
prokineticin 1
chr4_+_88896868 0.559 SPP1
secreted phosphoprotein 1
chr18_+_61254533 0.558 NM_012397
SERPINB13
serpin peptidase inhibitor, clade B (ovalbumin), member 13
chr21_+_42733916 0.552 NM_002463
LOC100131190
MX2
uncharacterized LOC100131190
myxovirus (influenza virus) resistance 2 (mouse)
chr1_+_230883129 0.549 NM_006615
NM_016452
CAPN9

calpain 9


Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.