Motif ID: PAX5.p2

Z-value: 1.734


Transcription factors associated with PAX5.p2:

Gene SymbolEntrez IDGene Name
PAX5 5079 paired box 5

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
PAX5hg19_v1_chr9_-_37034358_37034475-0.623.2e-09Click!


Activity profile for motif PAX5.p2.

activity profile for motif PAX5.p2


Sorted Z-values histogram for motif PAX5.p2

Sorted Z-values for motif PAX5.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of PAX5.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr16_-_325867 21.984 NM_003834
NM_183337
RGS11

regulator of G-protein signaling 11

chr1_-_85358851 15.744 NM_012152
LPAR3
lysophosphatidic acid receptor 3
chr15_+_101420004 11.006 NM_000693
ALDH1A3
aldehyde dehydrogenase 1 family, member A3
chr7_+_128470462 10.789 NM_001127487
NM_001458
FLNC

filamin C, gamma

chr20_-_62130390 10.527 NM_001958
EEF1A2
eukaryotic translation elongation factor 1 alpha 2
chr9_-_86153048 10.494 NM_001244959
NM_174938
FRMD3

FERM domain containing 3

chr9_+_33750463 10.340 NM_001197097
NM_007343
NM_001197098
PRSS3


protease, serine, 3


chr5_-_168727715 9.679 NM_003062
SLIT3
slit homolog 3 (Drosophila)
chr15_+_101420032 8.564 ALDH1A3
aldehyde dehydrogenase 1 family, member A3
chr2_-_216300770 8.402 NM_002026
NM_054034
NM_212474
NM_212476
NM_212478
NM_212482
FN1





fibronectin 1





chr7_-_108096693 7.923 NM_001193582
NM_001193583
NM_001193584
NM_005010
NRCAM



neuronal cell adhesion molecule



chr10_+_135192694 7.830 NM_152911
NM_207127
NM_207128
PAOX


polyamine oxidase (exo-N4-amino)


chr8_+_1922030 7.553 NM_014867
KBTBD11
kelch repeat and BTB (POZ) domain containing 11
chr5_-_1112106 7.408 NM_006598
SLC12A7
solute carrier family 12 (potassium/chloride transporters), member 7
chr1_+_10057254 7.148 NM_052960
RBP7
retinol binding protein 7, cellular
chr14_-_95786095 7.114 NM_024734
CLMN
calmin (calponin-like, transmembrane)
chr11_+_46403260 6.470 MDK
midkine (neurite growth-promoting factor 2)
chr16_-_67700571 6.300 NM_032140
C16orf48
chromosome 16 open reading frame 48
chr5_-_60140041 6.091 NM_001104558
NM_024930
ELOVL7

ELOVL fatty acid elongase 7

chr2_-_216300444 5.900 FN1
fibronectin 1
chr20_+_44098392 5.832 NM_006103
WFDC2
WAP four-disulfide core domain 2
chr2_-_99347430 5.719 MGAT4A
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
chr4_-_177713664 5.522 NM_005429
VEGFC
vascular endothelial growth factor C
chr11_+_46403205 5.470 NM_002391
MDK
midkine (neurite growth-promoting factor 2)
chr8_-_91997437 5.460 NM_001190972
LOC100127983
uncharacterized LOC100127983
chr1_-_115632047 5.373 NM_005725
TSPAN2
tetraspanin 2
chr21_-_46293598 5.170 PTTG1IP
pituitary tumor-transforming 1 interacting protein
chr13_-_110438896 5.110 NM_003749
IRS2
insulin receptor substrate 2
chr2_+_24272627 5.092 FKBP1B
FK506 binding protein 1B, 12.6 kDa
chr3_-_197282805 5.076 NM_004051
NM_203314
BDH1

3-hydroxybutyrate dehydrogenase, type 1

chr16_+_2039945 5.069 NM_004209
SYNGR3
synaptogyrin 3
chr21_-_46293532 5.065 PTTG1IP
pituitary tumor-transforming 1 interacting protein
chr19_-_2721337 5.021 NM_145173
DIRAS1
DIRAS family, GTP-binding RAS-like 1
chr21_-_46293561 5.008 PTTG1IP
pituitary tumor-transforming 1 interacting protein
chr18_+_9708187 4.973 NM_006868
RAB31
RAB31, member RAS oncogene family
chr5_+_68788387 4.972 NM_001205254
OCLN
occludin
chr8_-_133493003 4.940 NM_004519
KCNQ3
potassium voltage-gated channel, KQT-like subfamily, member 3
chr19_-_19006868 4.914 NM_021267
NM_198207
NM_001492
CERS1

GDF1
ceramide synthase 1

growth differentiation factor 1
chr20_+_35169897 4.866 MYL9
myosin, light chain 9, regulatory
chr21_-_46293609 4.857 NM_004339
PTTG1IP
pituitary tumor-transforming 1 interacting protein
chr2_+_30454396 4.776 NM_030915
LBH
limb bud and heart development homolog (mouse)
chr20_+_35169876 4.638 NM_006097
NM_181526
MYL9

myosin, light chain 9, regulatory

chr2_-_1748240 4.603 PXDN
peroxidasin homolog (Drosophila)
chr8_+_13424351 4.543 NM_001007090
C8orf48
chromosome 8 open reading frame 48
chr22_+_24577443 4.515 NM_019601
SUSD2
sushi domain containing 2
chr19_+_7580987 4.513 NM_018083
ZNF358
zinc finger protein 358
chr14_+_94640648 4.465 NM_020958
NM_058237
PPP4R4

protein phosphatase 4, regulatory subunit 4

chr12_+_66218879 4.451 HMGA2
high mobility group AT-hook 2
chr18_+_9708322 4.450 RAB31
RAB31, member RAS oncogene family
chr5_+_76011780 4.413 NM_001992
F2R
coagulation factor II (thrombin) receptor
chr12_+_57998600 4.405 NM_178502
DTX3
deltex homolog 3 (Drosophila)
chr8_+_22457098 4.392 NM_001013842
NM_001198827
NM_173686
C8orf58


chromosome 8 open reading frame 58


chr13_-_41768533 4.372 NM_032138
KBTBD7
kelch repeat and BTB (POZ) domain containing 7
chr20_+_59827452 4.353 NM_001794
CDH4
cadherin 4, type 1, R-cadherin (retinal)
chr2_-_1748285 4.350 NM_012293
PXDN
peroxidasin homolog (Drosophila)
chr4_-_83483099 4.334 NM_001080506
TMEM150C
transmembrane protein 150C
chr6_+_19837599 4.293 NM_001546
ID4
inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
chr6_+_132129154 4.289 NM_006208
ENPP1
ectonucleotide pyrophosphatase/phosphodiesterase 1
chr2_-_99347588 4.270 NM_012214
MGAT4A
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
chr2_-_1748317 4.265 PXDN
peroxidasin homolog (Drosophila)
chr2_+_26395959 4.254 NM_001168241
FAM59B
family with sequence similarity 59, member B
chr11_-_119187811 4.238 NM_006500
MCAM
melanoma cell adhesion molecule
chr5_+_71403040 4.237 NM_005909
MAP1B
microtubule-associated protein 1B
chr16_+_55512801 4.216 NM_004530
MMP2
matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
chr2_-_1748213 4.209 PXDN
peroxidasin homolog (Drosophila)
chr1_+_111889194 4.205 NM_181643
C1orf88
chromosome 1 open reading frame 88
chr15_-_101459410 4.200


chr9_+_131183122 4.196 CERCAM
cerebral endothelial cell adhesion molecule
chr1_-_40254521 4.194 NM_001720
BMP8B
bone morphogenetic protein 8b
chr10_-_62703822 4.173 NM_001242359
NM_014836
RHOBTB1

Rho-related BTB domain containing 1

chr12_-_76425207 4.142 PHLDA1
pleckstrin homology-like domain, family A, member 1
chr10_+_17270469 4.072 VIM
vimentin
chr6_-_160114186 4.068 SOD2
superoxide dismutase 2, mitochondrial
chr2_+_24272583 3.998 NM_004116
NM_054033
FKBP1B

FK506 binding protein 1B, 12.6 kDa

chr21_+_47518012 3.976 NM_001849
NM_058174
NM_058175
COL6A2


collagen, type VI, alpha 2


chr12_+_132312917 3.913 NM_016155
MMP17
matrix metallopeptidase 17 (membrane-inserted)
chr14_+_71108373 3.861 NM_015351
TTC9
tetratricopeptide repeat domain 9
chr2_-_20212408 3.827 MATN3
matrilin 3
chr2_+_207308280 3.827 NM_003812
ADAM23
ADAM metallopeptidase domain 23
chr22_-_37823503 3.783 NM_052906
ELFN2
extracellular leucine-rich repeat and fibronectin type III domain containing 2
chr8_-_11324184 3.771 NM_053279
FAM167A
family with sequence similarity 167, member A
chr1_+_150122415 3.710 PLEKHO1
pleckstrin homology domain containing, family O member 1
chr15_+_39873276 3.693 NM_003246
THBS1
thrombospondin 1
chrX_+_18443702 3.677 NM_003159
CDKL5
cyclin-dependent kinase-like 5
chr17_+_42836546 3.666 NM_002390
ADAM11
ADAM metallopeptidase domain 11
chr2_+_62423260 3.657 NM_006577
B3GNT2
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
chr13_-_41768392 3.640 KBTBD7
kelch repeat and BTB (POZ) domain containing 7
chr12_-_76425375 3.638 NM_007350
PHLDA1
pleckstrin homology-like domain, family A, member 1
chr14_-_92302612 3.636 NM_001128595
NM_152332
TC2N

tandem C2 domains, nuclear

chr12_+_26111951 3.623 NM_001164748
NM_007211
RASSF8

Ras association (RalGDS/AF-6) domain family (N-terminal) member 8

chr16_+_30194925 3.614 CORO1A
coronin, actin binding protein, 1A
chr22_+_24577417 3.609 SUSD2
sushi domain containing 2
chr16_+_30194730 3.597 NM_001193333
NM_007074
CORO1A

coronin, actin binding protein, 1A

chr5_-_114632240 3.565 NM_001040440
CCDC112
coiled-coil domain containing 112
chr2_-_20212448 3.557 NM_002381
MATN3
matrilin 3
chr11_+_46403279 3.551 MDK
midkine (neurite growth-promoting factor 2)
chr5_-_179780314 3.545 NM_005110
GFPT2
glutamine-fructose-6-phosphate transaminase 2
chr13_+_76210449 3.543 LMO7
LIM domain 7
chr11_+_46403302 3.538 NM_001012333
MDK
midkine (neurite growth-promoting factor 2)
chr1_-_20812271 3.532 CAMK2N1
calcium/calmodulin-dependent protein kinase II inhibitor 1
chr21_+_44073650 3.530 NM_001001567
NM_001001568
NM_001001569
NM_001001570
NM_001001571
NM_001001572
NM_001001573
NM_001001574
NM_001001575
NM_001001576
NM_001001577
NM_001001578
NM_001001579
NM_001001580
NM_001001581
NM_001001582
NM_001001583
NM_001001584
NM_001001585
NM_002606
PDE9A



















phosphodiesterase 9A



















chr1_-_40254131 3.526 BMP8B
bone morphogenetic protein 8b
chr1_-_94702916 3.442 ARHGAP29
Rho GTPase activating protein 29
chr1_+_25071967 3.440 CLIC4
chloride intracellular channel 4
chr19_+_54371170 3.419 MYADM
myeloid-associated differentiation marker
chr7_+_5322553 3.404 NM_001040661
NM_153247
SLC29A4

solute carrier family 29 (nucleoside transporters), member 4

chr12_+_569542 3.379 NM_173593
B4GALNT3
beta-1,4-N-acetyl-galactosaminyl transferase 3
chr18_+_9708269 3.370 RAB31
RAB31, member RAS oncogene family
chr3_+_10206562 3.349 NM_001570
IRAK2
interleukin-1 receptor-associated kinase 2
chr22_+_26825220 3.340 NM_020437
ASPHD2
aspartate beta-hydroxylase domain containing 2
chr20_-_36793646 3.339 NM_004613
NM_198951
TGM2

transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase)

chr2_+_97202463 3.339 NM_212481
ARID5A
AT rich interactive domain 5A (MRF1-like)
chr8_+_17013459 3.334 ZDHHC2
zinc finger, DHHC-type containing 2
chr1_-_94147201 3.320 NM_003567
BCAR3
breast cancer anti-estrogen resistance 3
chr1_-_94703252 3.311 NM_004815
ARHGAP29
Rho GTPase activating protein 29
chr15_-_52587851 3.306 NM_018728
MYO5C
myosin VC
chr7_-_105925329 3.297 NAMPT
nicotinamide phosphoribosyltransferase
chr1_-_1535446 3.269 NM_001242659
LOC643988
uncharacterized LOC643988
chr20_+_62328068 3.259 TNFRSF6B
tumor necrosis factor receptor superfamily, member 6b, decoy
chrX_-_152864621 3.254 NM_001130997
NM_152274
FAM58A

family with sequence similarity 58, member A

chr17_-_15466772 3.250 NM_001204478
NM_001135036
NM_145301
FAM18B2-CDRT4
FAM18B2

FAM18B2-CDRT4 readthrough
family with sequence similarity 18, member B2

chr11_+_46402333 3.245 NM_001012334
MDK
midkine (neurite growth-promoting factor 2)
chr1_+_162531229 3.225 NM_003115
UAP1
UDP-N-acteylglucosamine pyrophosphorylase 1
chr17_-_62658311 3.217 NM_022739
SMURF2
SMAD specific E3 ubiquitin protein ligase 2
chr2_+_170590241 3.217 NM_144711
KLHL23
kelch-like 23 (Drosophila)
chr19_+_54371150 3.213 MYADM
myeloid-associated differentiation marker
chr15_+_63335086 3.208 TPM1
tropomyosin 1 (alpha)
chr19_+_16187315 3.193 TPM4
tropomyosin 4
chr15_+_76135992 3.191 UBE2Q2
ubiquitin-conjugating enzyme E2Q family member 2
chr19_-_46000159 3.184 NM_005619
NM_206900
RTN2

reticulon 2

chr3_+_32280154 3.183 NM_178868
CMTM8
CKLF-like MARVEL transmembrane domain containing 8
chr17_-_29151638 3.178 CRLF3
cytokine receptor-like factor 3
chr10_-_62761197 3.175 RHOBTB1
Rho-related BTB domain containing 1
chrX_-_101771641 3.147 NM_021992
TMSB15A
TMSB15B
thymosin beta 15a
thymosin beta 15B
chrX_-_153151537 3.144


chr8_+_17013799 3.136 NM_016353
ZDHHC2
zinc finger, DHHC-type containing 2
chr1_+_16085245 3.127 NM_017556
FBLIM1
filamin binding LIM protein 1
chr19_+_54371125 3.107 NM_001020819
NM_138373
MYADM

myeloid-associated differentiation marker

chr6_+_132129195 3.097 ENPP1
ectonucleotide pyrophosphatase/phosphodiesterase 1
chr6_+_37137882 3.071 NM_001243186
NM_002648
PIM1

pim-1 oncogene

chrX_-_152864435 3.068 FAM58A
family with sequence similarity 58, member A
chr11_-_125366048 3.065 NM_005103
NM_022549
FEZ1

fasciculation and elongation protein zeta 1 (zygin I)

chr3_-_158450205 3.053 RARRES1
retinoic acid receptor responder (tazarotene induced) 1
chr2_+_37571752 3.030 NM_012413
QPCT
glutaminyl-peptide cyclotransferase
chr22_-_38966066 3.005 NM_007068
DMC1
DMC1 dosage suppressor of mck1 homolog, meiosis-specific homologous recombination (yeast)
chr11_-_27494232 2.997 NM_018490
LGR4
leucine-rich repeat containing G protein-coupled receptor 4
chr8_+_17014006 2.962 ZDHHC2
zinc finger, DHHC-type containing 2
chr17_-_62658175 2.957 SMURF2
SMAD specific E3 ubiquitin protein ligase 2
chr20_+_8112762 2.953 NM_015192
NM_182734
PLCB1

phospholipase C, beta 1 (phosphoinositide-specific)

chr9_+_91606349 2.952 NM_005226
S1PR3
sphingosine-1-phosphate receptor 3
chr18_+_18822168 2.947 NM_001142966
GREB1L
growth regulation by estrogen in breast cancer-like
chrX_-_38186782 2.939 NM_000328
NM_001034853
RPGR

retinitis pigmentosa GTPase regulator

chr19_-_291168 2.934 NM_177543
PPAP2C
phosphatidic acid phosphatase type 2C
chr4_+_77227882 2.931 STBD1
starch binding domain 1
chr2_+_210288668 2.921 NM_001039538
MAP2
microtubule-associated protein 2
chr9_+_131183225 2.921 CERCAM
cerebral endothelial cell adhesion molecule
chr1_-_20812727 2.917 NM_018584
CAMK2N1
calcium/calmodulin-dependent protein kinase II inhibitor 1
chr17_-_41623246 2.917 NM_001986
ETV4
ets variant 4
chr10_+_17270257 2.899 NM_003380
VIM
vimentin
chr13_+_98795468 2.895 FARP1
FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
chr6_-_170600165 2.894


chr22_-_20255614 2.891 NM_023004
RTN4R
reticulon 4 receptor
chr6_-_56708444 2.890 DST
dystonin
chr7_+_102074002 2.890 ORAI2
ORAI calcium release-activated calcium modulator 2
chr19_-_11529948 2.886 NM_001035223
NM_001161616
RGL3

ral guanine nucleotide dissociation stimulator-like 3

chr8_+_25042066 2.869 DOCK5
dedicator of cytokinesis 5
chr12_+_93964801 2.866 SOCS2
suppressor of cytokine signaling 2
chr11_-_12030622 2.856 NM_015881
DKK3
dickkopf 3 homolog (Xenopus laevis)
chr9_+_4490193 2.841 NM_004170
SLC1A1
solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
chr2_-_96657538 2.835 ANKRD36C
ankyrin repeat domain 36C
chr17_+_16945766 2.831 NM_015134
NM_201274
MPRIP

myosin phosphatase Rho interacting protein

chr12_+_53491448 2.799 IGFBP6
insulin-like growth factor binding protein 6
chr7_+_89840999 2.776 NM_001244944
NM_001244945
NM_152999
NM_001040665
NM_001244946
STEAP2




STEAP family member 2, metalloreductase




chr12_-_96184346 2.766 NTN4
netrin 4
chr14_+_105992930 2.759 NM_025268
TMEM121
transmembrane protein 121
chr5_+_52284903 2.756 NM_002203
ITGA2
integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
chr9_+_130374466 2.756 NM_001032221
NM_003165
STXBP1

syntaxin binding protein 1

chr9_-_130331350 2.753 NM_022833
FAM129B
family with sequence similarity 129, member B
chr3_+_32280211 2.745 CMTM8
CKLF-like MARVEL transmembrane domain containing 8
chr12_+_27933162 2.728 NM_020782
KLHDC5
kelch domain containing 5
chr1_-_95392501 2.728 NM_001839
CNN3
calponin 3, acidic
chr1_+_25071906 2.725 CLIC4
chloride intracellular channel 4
chr16_-_90085786 2.725 NM_001042610
DBNDD1
dysbindin (dystrobrevin binding protein 1) domain containing 1
chr5_+_148651443 2.715 AFAP1L1
actin filament associated protein 1-like 1
chr12_-_96184510 2.712 NM_021229
NTN4
netrin 4
chrX_+_102632108 2.692 NM_014380
NGFRAP1
nerve growth factor receptor (TNFRSF16) associated protein 1
chr11_-_128391888 2.685 ETS1
v-ets erythroblastosis virus E26 oncogene homolog 1 (avian)
chr2_+_170590454 2.676 KLHL23
kelch-like 23 (Drosophila)
chrX_+_43514157 2.672 MAOA
monoamine oxidase A
chr11_-_33722285 2.670 NM_001166692
C11orf91
chromosome 11 open reading frame 91
chr3_+_36421944 2.661 NM_003149
STAC
SH3 and cysteine rich domain
chr6_-_160114318 2.661 NM_000636
NM_001024465
NM_001024466
SOD2


superoxide dismutase 2, mitochondrial


chr4_-_170191989 2.646 SH3RF1
SH3 domain containing ring finger 1
chr6_+_151561653 2.646 AKAP12
A kinase (PRKA) anchor protein 12
chr7_-_143059696 2.643 NM_001031690
FAM131B
family with sequence similarity 131, member B
chr16_+_3096681 2.643 NM_022468
MMP25
matrix metallopeptidase 25
chr11_-_32452358 2.640 NM_001198551
NM_001198552
WT1

Wilms tumor 1

chr17_-_29151724 2.624 NM_015986
CRLF3
cytokine receptor-like factor 3
chrY_-_1521733 2.608 NM_001173474
NM_004192
ASMTL

acetylserotonin O-methyltransferase-like

chr8_-_145578502 2.597 NM_001252402
NM_001252404
C8ORFK29

uncharacterized LOC340393


Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
2.05 1.64e-12 GO:0009653 anatomical structure morphogenesis
2.69 1.05e-08 GO:0000904 cell morphogenesis involved in differentiation
2.26 1.25e-08 GO:0051128 regulation of cellular component organization
1.84 1.32e-08 GO:0023051 regulation of signaling
1.90 2.08e-08 GO:0009966 regulation of signal transduction
2.45 7.62e-08 GO:0000902 cell morphogenesis
2.36 1.76e-07 GO:0030030 cell projection organization
2.36 2.61e-07 GO:0032989 cellular component morphogenesis
2.68 5.24e-07 GO:0007409 axonogenesis
2.64 6.12e-07 GO:0048667 cell morphogenesis involved in neuron differentiation
2.59 1.14e-06 GO:0048812 neuron projection morphogenesis
1.63 1.77e-06 GO:0048523 negative regulation of cellular process
2.44 3.06e-06 GO:0048858 cell projection morphogenesis
2.42 4.20e-06 GO:0032990 cell part morphogenesis
2.44 4.53e-06 GO:0031175 neuron projection development
1.66 6.14e-06 GO:0048583 regulation of response to stimulus
1.97 1.50e-05 GO:0048468 cell development
2.20 1.56e-05 GO:0001932 regulation of protein phosphorylation
1.97 4.29e-05 GO:0048699 generation of neurons
1.94 4.96e-05 GO:0022008 neurogenesis
1.53 5.76e-05 GO:0048519 negative regulation of biological process
1.57 6.52e-05 GO:0048869 cellular developmental process
2.10 6.74e-05 GO:0042325 regulation of phosphorylation
2.07 8.48e-05 GO:0019220 regulation of phosphate metabolic process
2.07 8.48e-05 GO:0051174 regulation of phosphorus metabolic process
2.19 1.10e-04 GO:0048666 neuron development
1.57 1.13e-04 GO:0030154 cell differentiation
1.98 1.15e-04 GO:0031399 regulation of protein modification process
2.35 1.26e-04 GO:0060548 negative regulation of cell death
1.24 1.72e-04 GO:0050794 regulation of cellular process
1.67 2.55e-04 GO:0007399 nervous system development
1.42 2.59e-04 GO:0048856 anatomical structure development
2.55 2.80e-04 GO:0007411 axon guidance
3.33 2.84e-04 GO:0051272 positive regulation of cellular component movement
1.44 3.83e-04 GO:0048731 system development
1.79 3.93e-04 GO:0010646 regulation of cell communication
1.89 4.76e-04 GO:0040011 locomotion
1.21 6.54e-04 GO:0065007 biological regulation
1.70 6.77e-04 GO:0051641 cellular localization
2.61 7.87e-04 GO:0051270 regulation of cellular component movement
3.88 8.05e-04 GO:0010720 positive regulation of cell development
2.16 8.08e-04 GO:0006935 chemotaxis
2.16 8.08e-04 GO:0042330 taxis
2.56 8.24e-04 GO:0045860 positive regulation of protein kinase activity
1.36 9.28e-04 GO:0023052 signaling
1.49 9.84e-04 GO:0042221 response to chemical stimulus
1.97 1.04e-03 GO:0030182 neuron differentiation
2.47 1.90e-03 GO:0033674 positive regulation of kinase activity
2.64 1.92e-03 GO:0030334 regulation of cell migration
2.69 1.96e-03 GO:0050767 regulation of neurogenesis
4.23 2.00e-03 GO:0050769 positive regulation of neurogenesis
1.37 2.04e-03 GO:0007165 signal transduction
2.46 2.23e-03 GO:0060284 regulation of cell development
3.16 2.26e-03 GO:0040017 positive regulation of locomotion
2.61 2.52e-03 GO:2000145 regulation of cell motility
1.34 2.59e-03 GO:0032502 developmental process
1.76 2.90e-03 GO:0009605 response to external stimulus
2.40 3.86e-03 GO:0051347 positive regulation of transferase activity
2.18 4.50e-03 GO:0043066 negative regulation of apoptosis
3.13 4.63e-03 GO:0030335 positive regulation of cell migration
3.13 4.63e-03 GO:2000147 positive regulation of cell motility
1.20 4.85e-03 GO:0050789 regulation of biological process
2.12 5.53e-03 GO:0045859 regulation of protein kinase activity
2.16 5.83e-03 GO:0043069 negative regulation of programmed cell death
2.46 6.05e-03 GO:0040012 regulation of locomotion
2.31 6.90e-03 GO:0018193 peptidyl-amino acid modification
2.08 7.03e-03 GO:0043549 regulation of kinase activity
1.85 7.41e-03 GO:0016192 vesicle-mediated transport
2.47 8.22e-03 GO:0051960 regulation of nervous system development
1.71 8.79e-03 GO:0032268 regulation of cellular protein metabolic process
1.30 9.39e-03 GO:0051716 cellular response to stimulus
2.12 9.63e-03 GO:0051094 positive regulation of developmental process
1.39 1.10e-02 GO:0048518 positive regulation of biological process
11.25 1.12e-02 GO:0048710 regulation of astrocyte differentiation
1.90 1.22e-02 GO:0007167 enzyme linked receptor protein signaling pathway
2.19 1.28e-02 GO:0010627 regulation of intracellular protein kinase cascade
2.71 1.35e-02 GO:0045664 regulation of neuron differentiation
1.12 1.42e-02 GO:0009987 cellular process
2.69 1.63e-02 GO:0043405 regulation of MAP kinase activity
2.01 1.77e-02 GO:0051338 regulation of transferase activity
1.41 2.21e-02 GO:0048522 positive regulation of cellular process
2.32 2.22e-02 GO:0022603 regulation of anatomical structure morphogenesis
2.84 2.39e-02 GO:0071902 positive regulation of protein serine/threonine kinase activity
1.69 2.40e-02 GO:0032879 regulation of localization
1.80 2.49e-02 GO:2000026 regulation of multicellular organismal development
1.69 2.49e-02 GO:0042127 regulation of cell proliferation
2.68 2.64e-02 GO:0006887 exocytosis
1.71 2.76e-02 GO:0050793 regulation of developmental process
12.89 3.07e-02 GO:0032456 endocytic recycling
1.63 3.13e-02 GO:0051649 establishment of localization in cell
2.34 3.30e-02 GO:0071900 regulation of protein serine/threonine kinase activity
1.47 3.90e-02 GO:0006464 protein modification process
2.21 4.30e-02 GO:0045597 positive regulation of cell differentiation
1.32 4.57e-02 GO:0016043 cellular component organization
1.31 4.96e-02 GO:0007275 multicellular organismal development
1.96 4.99e-02 GO:0007599 hemostasis

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
1.26 7.07e-08 GO:0016020 membrane
1.20 1.50e-05 GO:0005737 cytoplasm
1.33 7.18e-05 GO:0005886 plasma membrane
1.32 1.64e-04 GO:0071944 cell periphery
1.46 6.24e-04 GO:0044459 plasma membrane part
1.23 7.29e-04 GO:0044444 cytoplasmic part
1.54 1.16e-03 GO:0012505 endomembrane system
1.44 3.28e-03 GO:0005829 cytosol
1.65 5.16e-03 GO:0005794 Golgi apparatus
2.77 1.16e-02 GO:0005912 adherens junction
1.19 1.89e-02 GO:0044425 membrane part
1.68 1.89e-02 GO:0031982 vesicle
1.75 4.39e-02 GO:0030054 cell junction
1.99 4.63e-02 GO:0048471 perinuclear region of cytoplasm
1.65 4.64e-02 GO:0031410 cytoplasmic vesicle
2.50 4.91e-02 GO:0070161 anchoring junction

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
1.24 5.26e-06 GO:0005515 protein binding
1.96 2.84e-03 GO:0008092 cytoskeletal protein binding
2.23 5.48e-03 GO:0003779 actin binding
13.75 3.76e-02 GO:0031994 insulin-like growth factor I binding
4.76 4.06e-02 GO:0050839 cell adhesion molecule binding
1.60 4.41e-02 GO:0030234 enzyme regulator activity