Motif ID: PAX4.p2

Z-value: 0.872


Transcription factors associated with PAX4.p2:

Gene SymbolEntrez IDGene Name
PAX4 5078 paired box 4



Activity profile for motif PAX4.p2.

activity profile for motif PAX4.p2


Sorted Z-values histogram for motif PAX4.p2

Sorted Z-values for motif PAX4.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of PAX4.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr19_+_1776117 10.834


chr1_+_212788359 10.477 NM_001206486
ATF3
activating transcription factor 3
chr19_+_2977480 9.811 NM_001143986
NM_024760
TLE6

transducin-like enhancer of split 6 (E(sp1) homolog, Drosophila)

chr9_-_20622433 8.087 MLLT3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr7_+_134233848 8.083 NM_001080538
AKR1B15
aldo-keto reductase family 1, member B15
chr9_-_20622476 8.024 NM_004529
MLLT3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr1_-_162346579 6.612 NM_182581
C1orf111
chromosome 1 open reading frame 111
chr15_-_40401041 5.919 NM_001003940
BMF
Bcl2 modifying factor
chr11_+_44785975 5.603 NM_130783
TSPAN18
tetraspanin 18
chr17_-_46035109 4.751 NM_024320
PRR15L
proline rich 15-like
chr1_+_145524989 4.665 NM_003637
ITGA10
integrin, alpha 10
chr10_+_91152321 3.877 NM_001548
IFIT1
interferon-induced protein with tetratricopeptide repeats 1
chr5_+_42756919 3.801 NM_001134848
CCDC152
coiled-coil domain containing 152
chr10_+_5136613 3.545 AKR1C3
aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
chr16_+_15528324 3.508 NM_033201
C16orf45
chromosome 16 open reading frame 45
chr16_-_28608367 3.480 NM_001054
SULT1A2
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
chr7_-_99277518 3.327 NM_000777
NM_001190484
CYP3A5

cytochrome P450, family 3, subfamily A, polypeptide 5

chr10_+_5136589 3.257 AKR1C3
aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
chr1_+_145525041 3.242 ITGA10
integrin, alpha 10
chr4_+_39184023 3.233 NM_025132
WDR19
WD repeat domain 19
chr18_-_65182507 3.198 DSEL
dermatan sulfate epimerase-like
chr7_+_128312345 3.036 NM_001012454
NM_001128926
FAM71F2

family with sequence similarity 71, member F2

chr22_-_43117270 2.975 A4GALT
alpha 1,4-galactosyltransferase
chrM_-_379 2.931


chr2_-_122042767 2.894 NM_014553
TFCP2L1
transcription factor CP2-like 1
chrX_+_43515406 2.883 NM_000240
MAOA
monoamine oxidase A
chr10_+_5136556 2.874 NM_003739
AKR1C3
aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
chr10_+_114709963 2.819 NM_001146274
NM_001146283
NM_001146284
NM_001146285
NM_001146286
NM_001198525
NM_001198526
NM_001198527
NM_001198528
NM_001198529
NM_001198530
NM_001198531
NM_030756
TCF7L2












transcription factor 7-like 2 (T-cell specific, HMG-box)












chr22_-_31688329 2.690 NM_001135911
NM_052880
PIK3IP1

phosphoinositide-3-kinase interacting protein 1

chr19_-_49622278 2.672 NM_018111
C19orf73
chromosome 19 open reading frame 73
chr17_+_25799024 2.648 NM_014238
KSR1
kinase suppressor of ras 1
chr11_+_20044362 2.579 NAV2
neuron navigator 2
chr6_-_33714681 2.549 NM_001142883
NM_054111
IP6K3

inositol hexakisphosphate kinase 3

chrX_+_30233674 2.511 NM_002364
MAGEB2
melanoma antigen family B, 2
chr4_-_84030995 2.395 NM_001130716
PLAC8
placenta-specific 8
chr3_-_112359251 2.389 CCDC80
coiled-coil domain containing 80
chr9_-_91793681 2.380 NM_016848
SHC3
SHC (Src homology 2 domain containing) transforming protein 3
chr12_+_56546203 2.372 NM_001199629
NM_002475
MYL6B

myosin, light chain 6B, alkali, smooth muscle and non-muscle

chr9_+_92219926 2.326 NM_006705
GADD45G
growth arrest and DNA-damage-inducible, gamma
chr3_-_112358510 2.324 CCDC80
coiled-coil domain containing 80
chr1_+_151032150 2.274 NM_006818
MLLT11
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
chr10_+_114135013 2.253 NM_203380
ACSL5
acyl-CoA synthetase long-chain family member 5
chr17_+_4854383 2.240 NM_001193503
NM_001976
NM_053013
ENO3


enolase 3 (beta, muscle)


chr14_+_39734475 2.222 NM_203354
CTAGE5
CTAGE family, member 5
chr1_-_182357871 2.219 GLUL
glutamate-ammonia ligase
chr1_-_182357757 2.185 GLUL
glutamate-ammonia ligase
chr2_-_151344145 2.173 NM_005168
RND3
Rho family GTPase 3
chr3_+_42530790 2.166 NM_001251882
VIPR1
vasoactive intestinal peptide receptor 1
chr3_+_194406614 2.157 NM_153690
FAM43A
family with sequence similarity 43, member A
chr6_+_126240369 2.140 NM_001199622
NCOA7
nuclear receptor coactivator 7
chr1_+_151032880 2.113 MLLT11
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
chr2_+_11680079 2.096 NM_148903
GREB1
growth regulation by estrogen in breast cancer 1
chr17_-_47841468 2.077 FAM117A
family with sequence similarity 117, member A
chr1_+_151032683 2.073 MLLT11
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
chr3_+_9975513 2.047 NM_015513
NM_001031717
NM_001077415
CRELD1


cysteine-rich with EGF-like domains 1


chr3_-_112358758 2.017 CCDC80
coiled-coil domain containing 80
chr1_+_151032906 2.008 MLLT11
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
chr11_+_20385230 1.943 NM_006410
NM_001098521
HTATIP2

HIV-1 Tat interactive protein 2, 30kDa

chr11_+_20385324 1.927 NM_001098522
HTATIP2
HIV-1 Tat interactive protein 2, 30kDa
chrX_-_15620191 1.918 NM_021804
ACE2
angiotensin I converting enzyme (peptidyl-dipeptidase A) 2
chr5_-_142783059 1.906 NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr17_-_47841517 1.899 NM_030802
FAM117A
family with sequence similarity 117, member A
chr5_-_142783288 1.888 NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr17_-_71088814 1.887 SLC39A11
solute carrier family 39 (metal ion transporter), member 11
chr19_+_49622480 1.875 NM_003660
PPFIA3
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
chr9_+_129677046 1.847 NM_001190729
NM_001190730
NM_014636
RALGPS1


Ral GEF with PH domain and SH3 binding motif 1


chr11_+_20385259 1.830 NM_001098520
HTATIP2
HIV-1 Tat interactive protein 2, 30kDa
chr10_+_70980058 1.792 NM_025130
HKDC1
hexokinase domain containing 1
chr12_-_57644905 1.789 NM_145064
STAC3
SH3 and cysteine rich domain 3
chr1_-_182360181 1.744 GLUL
glutamate-ammonia ligase
chr5_-_95748688 1.741 NM_001177876
PCSK1
proprotein convertase subtilisin/kexin type 1
chrX_+_155227245 1.735 NM_002186
IL9R
interleukin 9 receptor
chrM_-_15569 1.710


chr2_-_85839178 1.675 NM_001013649
C2orf68
chromosome 2 open reading frame 68
chrY_+_59330251 1.671 NM_002186
IL9R
interleukin 9 receptor
chr1_-_1623942 1.666 SLC35E2B
SLC35E2
solute carrier family 35, member E2B
solute carrier family 35, member E2
chr17_-_71088820 1.650 SLC39A11
solute carrier family 39 (metal ion transporter), member 11
chr3_+_69134057 1.645 NM_006407
ARL6IP5
ADP-ribosylation-like factor 6 interacting protein 5
chr7_+_133812051 1.641 NM_144648
LRGUK
leucine-rich repeats and guanylate kinase domain containing
chr1_-_204463512 1.624 PIK3C2B
phosphoinositide-3-kinase, class 2, beta polypeptide
chr17_-_71088831 1.602 SLC39A11
solute carrier family 39 (metal ion transporter), member 11
chr2_-_109605668 1.596 NM_022336
EDAR
ectodysplasin A receptor
chr22_-_39640956 1.588 NM_002608
PDGFB
platelet-derived growth factor beta polypeptide
chr1_+_78354199 1.526 NM_001172309
NM_144573
NEXN

nexilin (F actin binding protein)

chr11_+_10482677 1.498 NM_001172430
AMPD3
adenosine monophosphate deaminase 3
chr2_+_102979096 1.477 NM_003855
IL18R1
interleukin 18 receptor 1
chr11_+_86085777 1.468 NM_001156474
NM_021827
CCDC81

coiled-coil domain containing 81

chr14_+_104394751 1.462 NM_153046
TDRD9
tudor domain containing 9
chr4_-_85419386 1.441 NM_006168
NKX6-1
NK6 homeobox 1
chr16_-_28621279 1.440 NM_001055
NM_177529
SULT1A1

sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1

chr12_-_123717645 1.433 MPHOSPH9
M-phase phosphoprotein 9
chr2_-_85839179 1.431 C2orf68
chromosome 2 open reading frame 68
chr5_+_146614525 1.425 NM_001112724
NM_145001
STK32A

serine/threonine kinase 32A

chr22_-_36556781 1.424 NM_145640
APOL3
apolipoprotein L, 3
chr4_-_40516567 1.421 RBM47
RNA binding motif protein 47
chr1_-_31230594 1.415 LAPTM5
lysosomal protein transmembrane 5
chr16_+_71879858 1.401


chr7_-_99332715 1.395 NM_000765
CYP3A7
CYP3A5
cytochrome P450, family 3, subfamily A, polypeptide 7
cytochrome P450, family 3, subfamily A, polypeptide 5
chr2_-_214015053 1.395 NM_016260
IKZF2
IKAROS family zinc finger 2 (Helios)
chr3_-_142166782 1.383 NM_001042604
NM_019001
XRN1

5'-3' exoribonuclease 1

chr10_-_61900659 1.372 NM_001149
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr2_-_85839147 1.363 C2orf68
chromosome 2 open reading frame 68
chr19_-_55660557 1.361 NM_001126132
NM_001126133
NM_003283
TNNT1


troponin T type 1 (skeletal, slow)


chr1_-_182360889 1.350 GLUL
glutamate-ammonia ligase
chr17_-_71088832 1.348 NM_001159770
NM_139177
SLC39A11

solute carrier family 39 (metal ion transporter), member 11

chr9_-_27573444 1.345 NM_018325
C9orf72
chromosome 9 open reading frame 72
chr8_-_124544376 1.341 NM_148177
FBXO32
F-box protein 32
chr5_-_142783225 1.339 NM_000176
NM_001020825
NM_001024094
NM_001204258
NM_001204259
NM_001204260
NM_001204261
NM_001204262
NM_001204263
NM_001204264
NM_001204265
NR3C1










nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)










chr16_-_67223998 1.337 NM_178516
EXOC3L1
exocyst complex component 3-like 1
chr6_-_31698033 1.337 NM_013974
DDAH2
dimethylarginine dimethylaminohydrolase 2
chr6_+_25963398 1.332 TRIM38
tripartite motif containing 38
chr12_-_10542616 1.322 NM_007360
KLRK1
killer cell lectin-like receptor subfamily K, member 1
chr5_-_154230157 1.317 C5orf4
chromosome 5 open reading frame 4
chr11_+_6518489 1.308 NM_144666
NM_173589
DNHD1

dynein heavy chain domain 1

chr11_+_1874199 1.298 NM_002339
LSP1
lymphocyte-specific protein 1
chr16_-_75150617 1.296 LDHD
lactate dehydrogenase D
chr6_-_31697953 1.288 DDAH2
dimethylarginine dimethylaminohydrolase 2
chr1_-_1677430 1.287 NM_001199787
NM_182838
SLC35E2B
SLC35E2

solute carrier family 35, member E2B
solute carrier family 35, member E2

chr3_-_73673978 1.267 NM_015009
PDZRN3
PDZ domain containing ring finger 3
chr5_+_81601165 1.267 NM_001017971
ATP6AP1L
ATPase, H+ transporting, lysosomal accessory protein 1-like
chr1_-_1624145 1.256 SLC35E2B
solute carrier family 35, member E2B
chr12_+_10365415 1.247 NM_031412
GABARAPL1
GABA(A) receptor-associated protein like 1
chr10_+_91092238 1.236 NM_001031683
IFIT3
interferon-induced protein with tetratricopeptide repeats 3
chr3_-_17741511 1.236 NM_001134381
TBC1D5
TBC1 domain family, member 5
chr2_-_122247903 1.223 CLASP1
cytoplasmic linker associated protein 1
chr18_-_53255734 1.214 NM_001083962
NM_001243230
NM_003199
TCF4


transcription factor 4


chr12_+_104659046 1.212 RPL18A
ribosomal protein L18a
chrM_+_14601 1.199


chr9_-_86983412 1.195 NM_022127
SLC28A3
solute carrier family 28 (sodium-coupled nucleoside transporter), member 3
chr6_+_134758840 1.184 LOC154092
uncharacterized LOC154092
chr9_-_118416 1.170 NM_207305
FOXD4
forkhead box D4
chr5_+_76382458 1.162 LOC728723
uncharacterized LOC728723
chrM_+_5769 1.139


chr12_+_11081833 1.138 NM_005042
NM_001110213
PRH2

proline-rich protein HaeIII subfamily 2

chr5_-_172662085 1.134 NM_001166175
NM_001166176
NM_004387
NKX2-5


NK2 homeobox 5


chr5_-_154230212 1.129 NM_032385
C5orf4
chromosome 5 open reading frame 4
chr1_-_1624180 1.106 NM_001110781
SLC35E2B
solute carrier family 35, member E2B
chr3_+_150803448 1.099 MED12L
mediator complex subunit 12-like
chr3_-_142166862 1.096 XRN1
5'-3' exoribonuclease 1
chr5_-_95158465 1.090 NM_001118890
NM_001243658
NM_001243659
NM_002064
GLRX



glutaredoxin (thioltransferase)



chr1_-_149889362 1.083 NM_014849
SV2A
synaptic vesicle glycoprotein 2A
chr9_+_79115548 1.073 NM_001097636
GCNT1
glucosaminyl (N-acetyl) transferase 1, core 2
chr5_+_162930230 1.061 NM_182796
MAT2B
methionine adenosyltransferase II, beta
chr11_-_66115016 1.060 NM_006876
B3GNT1
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1
chr19_-_18888728 1.059


chr11_+_100557851 1.053 NM_152432
ARHGAP42
Rho GTPase activating protein 42
chr3_-_112359277 1.051 CCDC80
coiled-coil domain containing 80
chr1_-_150978879 1.047 NM_001163259
NM_001163260
NM_001040217
FAM63A


family with sequence similarity 63, member A


chr8_+_17434700 1.027 PDGFRL
platelet-derived growth factor receptor-like
chr21_+_15588465 1.027 NM_144770
RBM11
RNA binding motif protein 11
chrX_-_15402469 1.026 NM_004469
FIGF
c-fos induced growth factor (vascular endothelial growth factor D)
chr11_-_67211291 1.026 NM_001018070
CORO1B
coronin, actin binding protein, 1B
chr4_-_141074122 1.022 MAML3
mastermind-like 3 (Drosophila)
chr6_+_25962978 1.015 NM_006355
TRIM38
tripartite motif containing 38
chr1_-_44482996 1.013 NM_006934
NM_201649
SLC6A9

solute carrier family 6 (neurotransmitter transporter, glycine), member 9

chr1_+_46016524 1.008 AKR1A1
aldo-keto reductase family 1, member A1 (aldehyde reductase)
chrX_-_131623994 1.003 NM_001170704
MBNL3
muscleblind-like 3 (Drosophila)
chr1_-_38397417 1.002 INPP5B
inositol polyphosphate-5-phosphatase, 75kDa
chr17_-_62914902 1.002 NM_199340
LRRC37A3
leucine rich repeat containing 37, member A3
chr3_-_9290592 0.990 SRGAP3
SLIT-ROBO Rho GTPase activating protein 3
chr11_+_72975569 0.989 NM_176796
NM_176797
P2RY6

pyrimidinergic receptor P2Y, G-protein coupled, 6

chr1_+_46016454 0.985 NM_001202413
NM_001202414
NM_006066
NM_153326
AKR1A1



aldo-keto reductase family 1, member A1 (aldehyde reductase)



chr17_-_1412995 0.977 INPP5K
inositol polyphosphate-5-phosphatase K
chr5_+_31799030 0.973 NM_178140
PDZD2
PDZ domain containing 2
chr4_-_40517913 0.964 NM_019027
RBM47
RNA binding motif protein 47
chr3_+_29322802 0.958 NM_001003792
NM_001003793
NM_001177711
NM_001177712
NM_014483
RBMS3




RNA binding motif, single stranded interacting protein 3




chr2_+_232120777 0.955


chr17_-_8063946 0.934 VAMP2
vesicle-associated membrane protein 2 (synaptobrevin 2)
chr4_+_41614725 0.929 LIMCH1
LIM and calponin homology domains 1
chr1_-_150669499 0.927 NM_018178
GOLPH3L
golgi phosphoprotein 3-like
chr5_-_154230148 0.927 C5orf4
chromosome 5 open reading frame 4
chr10_-_70092648 0.926 NM_001033083
NM_022129
PBLD

phenazine biosynthesis-like protein domain containing

chr6_+_42750465 0.926 FLJ38717
FLJ38717 protein
chr6_+_159070994 0.922 NM_001009991
NM_001242384
NM_001242394
NM_001242395
SYTL3



synaptotagmin-like 3



chr6_+_42751155 0.922 FLJ38717
FLJ38717 protein
chr14_+_24836144 0.912 NM_001136022
NM_001198967
NFATC4

nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4

chr4_+_86851425 0.911 NM_031305
ARHGAP24
Rho GTPase activating protein 24
chr6_-_49754899 0.894 NM_138733
PGK2
phosphoglycerate kinase 2
chr12_-_91572328 0.891 NM_133504
NM_133505
NM_133506
NM_133507
DCN



decorin



chr9_-_91793375 0.891 SHC3
SHC (Src homology 2 domain containing) transforming protein 3
chr20_+_32250089 0.888 NM_080825
C20orf144
chromosome 20 open reading frame 144
chr12_-_10562142 0.887 NM_013431
KLRC4-KLRK1
KLRC4
KLRC4-KLRK1 readthrough
killer cell lectin-like receptor subfamily C, member 4
chr11_-_62474666 0.877 BSCL2
Berardinelli-Seip congenital lipodystrophy 2 (seipin)
chr15_+_80390757 0.876 NM_001242919
ZFAND6
zinc finger, AN1-type domain 6
chr3_+_15643139 0.876 NM_000060
BTD
biotinidase
chr4_+_123091757 0.869 NM_015312
KIAA1109
KIAA1109
chr9_-_69202203 0.865 NM_001085476
FOXD4L6
forkhead box D4-like 6
chr19_-_49955025 0.863 NM_017916
PIH1D1
PIH1 domain containing 1
chr5_-_93447237 0.860 NM_001163417
NM_001163418
NM_032042
FAM172A


family with sequence similarity 172, member A


chr11_+_65271145 0.859


chr1_+_43282775 0.859 NM_001017922
ERMAP
erythroblast membrane-associated protein (Scianna blood group)
chr5_+_147258273 0.851 NM_054023
SCGB3A2
secretoglobin, family 3A, member 2
chr3_+_186383770 0.850 NM_000412
HRG
histidine-rich glycoprotein
chr19_-_55628780 0.846 NM_017607
PPP1R12C
protein phosphatase 1, regulatory subunit 12C
chr16_+_71879893 0.840 NM_001137675
ATXN1L
ataxin 1-like
chr8_-_146228214 0.839 ZNF252
zinc finger protein 252
chrX_-_131547536 0.832 NM_001170701
NM_001170702
NM_001170703
MBNL3


muscleblind-like 3 (Drosophila)


chr13_+_49822046 0.820 NM_001193478
NM_030911
CDADC1

cytidine and dCMP deaminase domain containing 1

chr6_-_36164973 0.813


chr11_+_113931228 0.812 NM_001018011
ZBTB16
zinc finger and BTB domain containing 16

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.