Motif ID: NRF1.p2

Z-value: 4.763


Transcription factors associated with NRF1.p2:

Gene SymbolEntrez IDGene Name
NRF1 4899 nuclear respiratory factor 1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
NRF1hg19_v1_chr7_+_129251529_129251554-0.291.3e-02Click!


Activity profile for motif NRF1.p2.

activity profile for motif NRF1.p2


Sorted Z-values histogram for motif NRF1.p2

Sorted Z-values for motif NRF1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NRF1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr17_+_260092 30.149 NM_001013672
C17orf97
chromosome 17 open reading frame 97
chr3_-_73673978 27.751 NM_015009
PDZRN3
PDZ domain containing ring finger 3
chr19_-_55770340 27.426 PPP6R1
protein phosphatase 6, regulatory subunit 1
chr19_-_46405854 25.602 NM_001012643
MYPOP
Myb-related transcription factor, partner of profilin
chrX_+_7065820 23.416 STS
steroid sulfatase (microsomal), isozyme S
chr19_-_55769920 18.704 NM_014931
PPP6R1
protein phosphatase 6, regulatory subunit 1
chr19_-_44258971 15.958 SMG9
smg-9 homolog, nonsense mediated mRNA decay factor (C. elegans)
chr19_-_55769844 15.911 PPP6R1
protein phosphatase 6, regulatory subunit 1
chr19_+_49588685 15.757 SNRNP70
small nuclear ribonucleoprotein 70kDa (U1)
chr15_-_76352068 15.338 NRG4
neuregulin 4
chr19_+_54041332 15.333 NM_001079906
NM_001253798
NM_001253799
ZNF331


zinc finger protein 331


chr19_-_44100127 15.310 NM_001007561
IRGQ
immunity-related GTPase family, Q
chr19_+_58898634 15.003 NM_001009
RPS5
ribosomal protein S5
chr19_-_50432731 14.991 NUP62
nucleoporin 62kDa
chr19_-_44259072 14.976 SMG9
smg-9 homolog, nonsense mediated mRNA decay factor (C. elegans)
chr19_-_50432679 14.872 NUP62
IL4I1
nucleoporin 62kDa
interleukin 4 induced 1
chr19_-_50432734 14.862 NM_012346
NM_153718
NM_153719
NM_001193357
NM_172374
NUP62



IL4I1
nucleoporin 62kDa



interleukin 4 induced 1
chr16_-_2390737 14.844 NM_001089
ABCA3
ATP-binding cassette, sub-family A (ABC1), member 3
chr2_+_228736326 14.390 NM_178821
WDR69
WD repeat domain 69
chr19_+_44100543 14.210 NM_024327
ZNF576
zinc finger protein 576
chr19_+_56165415 14.184 NM_001012478
NM_007279
U2AF2

U2 small nuclear RNA auxiliary factor 2

chr19_+_59056017 13.975 TRIM28
tripartite motif containing 28
chr22_-_31742217 13.823 NM_014323
NM_032050
NM_032051
NM_032052
PATZ1



POZ (BTB) and AT hook containing zinc finger 1



chr19_-_50432678 13.585 NUP62
nucleoporin 62kDa
chr19_-_44259115 13.447 NM_019108
SMG9
smg-9 homolog, nonsense mediated mRNA decay factor (C. elegans)
chr19_+_59055866 13.413 TRIM28
tripartite motif containing 28
chr19_+_54057898 13.344 NM_001253801
ZNF331
zinc finger protein 331
chr19_-_58662144 13.189 NM_024620
ZNF329
zinc finger protein 329
chr3_+_49449753 12.824 TCTA
T-cell leukemia translocation altered gene
chr19_+_37862055 12.710 NM_032453
ZNF527
zinc finger protein 527
chr19_+_39109684 12.515 NM_013234
EIF3K
eukaryotic translation initiation factor 3, subunit K
chr19_+_59055826 12.235 NM_005762
TRIM28
tripartite motif containing 28
chr19_+_42724498 12.076 ZNF526
zinc finger protein 526
chr19_+_42724431 11.942 NM_133444
ZNF526
zinc finger protein 526
chr10_-_134145325 11.887 STK32C
serine/threonine kinase 32C
chr10_-_134145333 11.873 STK32C
serine/threonine kinase 32C
chr19_+_44100734 11.764 NM_001145347
ZNF576
zinc finger protein 576
chr17_+_43971655 11.759 NM_001123066
NM_001123067
NM_001203251
NM_001203252
NM_005910
NM_016834
NM_016835
NM_016841
MAPT







microtubule-associated protein tau







chr19_-_42721802 11.626 NM_133328
DEDD2
death effector domain containing 2
chrX_-_153707595 11.563 NM_006014
LAGE3
L antigen family, member 3
chr19_+_54606141 11.356 NM_004542
NDUFA3
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa
chr19_+_54960380 11.198 LENG8
leukocyte receptor cluster (LRC) member 8
chr19_+_56111600 11.123 NM_153219
ZNF524
zinc finger protein 524
chr19_+_56159400 11.093 CCDC106
coiled-coil domain containing 106
chr19_-_56632644 11.005 NM_001002836
ZNF787
zinc finger protein 787
chr19_-_50432952 10.997 NM_016553
NUP62
nucleoporin 62kDa
chr5_+_52095929 10.930 PELO
pelota homolog (Drosophila)
chr19_+_39138288 10.689 ACTN4
actinin, alpha 4
chr19_+_39138306 10.608 ACTN4
actinin, alpha 4
chr16_-_2390593 10.556 ABCA3
ATP-binding cassette, sub-family A (ABC1), member 3
chr19_-_44079707 10.404 NM_006297
XRCC1
X-ray repair complementing defective repair in Chinese hamster cells 1
chr3_+_49449638 10.248 NM_022171
TCTA
T-cell leukemia translocation altered gene
chr19_+_49588716 10.137 SNRNP70
small nuclear ribonucleoprotein 70kDa (U1)
chr22_-_31741565 10.109 PATZ1
POZ (BTB) and AT hook containing zinc finger 1
chr16_+_89939992 9.987 NM_014972
TCF25
transcription factor 25 (basic helix-loop-helix)
chr19_+_39138314 9.742 ACTN4
actinin, alpha 4
chr19_-_48867149 9.740 NM_018273
TMEM143
transmembrane protein 143
chr19_+_39109807 9.663 EIF3K
eukaryotic translation initiation factor 3, subunit K
chr19_+_18794487 9.633 CRTC1
CREB regulated transcription coactivator 1
chr19_-_55918980 9.611 UBE2S
ubiquitin-conjugating enzyme E2S
chr19_+_18794391 9.527 NM_001098482
NM_015321
CRTC1

CREB regulated transcription coactivator 1

chr19_+_39109831 9.511 EIF3K
eukaryotic translation initiation factor 3, subunit K
chr19_+_49588660 9.466 SNRNP70
small nuclear ribonucleoprotein 70kDa (U1)
chr19_+_39138349 9.459 ACTN4
actinin, alpha 4
chr19_+_38397841 9.414 NM_015073
SIPA1L3
signal-induced proliferation-associated 1 like 3
chr20_+_25176333 9.369 NM_001114089
NM_001247
ENTPD6

ectonucleoside triphosphate diphosphohydrolase 6 (putative)

chr6_+_30614815 9.353 NM_001109938
NM_001161376
NM_145029
C6orf136


chromosome 6 open reading frame 136


chr19_-_44079609 9.348 XRCC1
X-ray repair complementing defective repair in Chinese hamster cells 1
chr19_-_58874078 9.325 NM_001207009
NM_198458
ZNF497

zinc finger protein 497

chr18_-_74534205 9.289 LOC100131655
uncharacterized LOC100131655
chr19_+_39109847 9.235 EIF3K
eukaryotic translation initiation factor 3, subunit K
chr16_-_4166021 9.146 ADCY9
adenylate cyclase 9
chr19_-_44124013 9.116 NM_182498
ZNF428
zinc finger protein 428
chr19_+_39109848 8.987 EIF3K
eukaryotic translation initiation factor 3, subunit K
chr19_-_36236291 8.976 NM_001040425
NM_144987
U2AF1L4

U2 small nuclear RNA auxiliary factor 1-like 4

chr19_-_38210625 8.919 NM_032689
ZNF607
zinc finger protein 607
chr19_+_49588399 8.852 NM_003089
SNRNP70
small nuclear ribonucleoprotein 70kDa (U1)
chr21_+_45553546 8.639 C21orf33
chromosome 21 open reading frame 33
chr19_+_39138265 8.621 NM_004924
ACTN4
actinin, alpha 4
chr19_-_59066303 8.611 CHMP2A
charged multivesicular body protein 2A
chr19_-_59066477 8.592 NM_014453
CHMP2A
charged multivesicular body protein 2A
chr19_-_40030759 8.515 NM_153232
EID2
EP300 interacting inhibitor of differentiation 2
chr19_-_59066353 8.507 NM_198426
CHMP2A
charged multivesicular body protein 2A
chr16_-_2390711 8.486 ABCA3
ATP-binding cassette, sub-family A (ABC1), member 3
chr19_-_59066372 8.443 CHMP2A
charged multivesicular body protein 2A
chr19_-_59066458 8.421 CHMP2A
charged multivesicular body protein 2A
chr10_+_102820914 8.395 NM_030929
KAZALD1
Kazal-type serine peptidase inhibitor domain 1
chr5_+_218355 8.385 NM_004168
SDHA
succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
chr16_+_15528324 8.333 NM_033201
C16orf45
chromosome 16 open reading frame 45
chr20_+_25176457 8.277 ENTPD6
ectonucleoside triphosphate diphosphohydrolase 6 (putative)
chr22_-_31742329 8.225 PATZ1
POZ (BTB) and AT hook containing zinc finger 1
chr14_-_102771469 8.195 NM_014226
MOK
MOK protein kinase
chr22_+_24200040 8.144 NM_001024939
SLC2A11
solute carrier family 2 (facilitated glucose transporter), member 11
chr19_+_38755097 8.071 NM_001166103
NM_021102
SPINT2

serine peptidase inhibitor, Kunitz type, 2

chr22_-_31741761 8.013 PATZ1
POZ (BTB) and AT hook containing zinc finger 1
chr12_+_122150638 8.005 NM_001080825
TMEM120B
transmembrane protein 120B
chr4_-_118006731 7.962 NM_152402
TRAM1L1
translocation associated membrane protein 1-like 1
chr19_-_47249629 7.948 STRN4
striatin, calmodulin binding protein 4
chr5_-_90679115 7.938 NM_020801
ARRDC3
arrestin domain containing 3
chr19_+_36236460 7.923 NM_172341
PSENEN
presenilin enhancer 2 homolog (C. elegans)
chr7_-_150974179 7.898 NM_003078
SMARCD3
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr15_+_96873845 7.866 NM_021005
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr7_-_149570763 7.850 LOC401431
uncharacterized LOC401431
chr1_+_3773844 7.786 NM_004402
DFFB
DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
chr14_+_65879439 7.770 FUT8
fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
chr10_-_38146978 7.698 ZNF248
zinc finger protein 248
chr2_-_33824294 7.634 NM_015475
FAM98A
family with sequence similarity 98, member A
chr10_-_16859389 7.627 RSU1
Ras suppressor protein 1
chr17_-_27278471 7.624 NM_001033561
NM_020889
PHF12

PHD finger protein 12

chr11_+_61447816 7.567 NM_006133
DAGLA
diacylglycerol lipase, alpha
chr16_+_89574804 7.561 NM_003119
NM_199367
SPG7

spastic paraplegia 7 (pure and complicated autosomal recessive)

chr1_+_231473773 7.561 C1orf124
chromosome 1 open reading frame 124
chr19_+_1753661 7.553 NM_001080488
ONECUT3
one cut homeobox 3
chr18_+_10526022 7.514 NAPG
N-ethylmaleimide-sensitive factor attachment protein, gamma
chr10_+_120967094 7.511 NM_005308
GRK5
G protein-coupled receptor kinase 5
chr22_-_39548448 7.490 NM_175709
CBX7
chromobox homolog 7
chr9_-_124922049 7.482 NM_014222
NDUFA8
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa
chr19_+_49956472 7.445 NM_001145396
NM_153329
ALDH16A1

aldehyde dehydrogenase 16 family, member A1

chr6_-_39197225 7.428 NM_003740
KCNK5
potassium channel, subfamily K, member 5
chr12_-_54070108 7.394 NM_005176
ATP5G2
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9)
chr6_-_24645955 7.390 NM_001168375
NM_001168376
NM_001168374
NM_001168377
NM_014809
KIAA0319




KIAA0319




chr19_+_18118921 7.328 NM_015683
ARRDC2
arrestin domain containing 2
chr5_+_218428 7.314 SDHA
succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
chr7_+_149571029 7.308 ATP6V0E2
ATPase, H+ transporting V0 subunit e2
chr19_+_38755238 7.277 SPINT2
serine peptidase inhibitor, Kunitz type, 2
chr1_+_167189948 7.250 NM_001198786
NM_002697
POU2F1

POU class 2 homeobox 1

chr19_+_49956492 7.237 ALDH16A1
aldehyde dehydrogenase 16 family, member A1
chr16_+_89940017 7.181 TCF25
transcription factor 25 (basic helix-loop-helix)
chr13_-_44361032 7.180 NM_001242863
NM_017993
ENOX1

ecto-NOX disulfide-thiol exchanger 1

chr10_-_16859336 7.126 RSU1
Ras suppressor protein 1
chr2_+_130939500 7.098 NM_025029
MZT2B
mitotic spindle organizing protein 2B
chr20_+_13976263 7.060 MACROD2
MACRO domain containing 2
chr19_+_984316 7.055 NM_024100
WDR18
WD repeat domain 18
chr19_-_59070324 6.983 NM_003969
UBE2M
ubiquitin-conjugating enzyme E2M
chr19_+_58978336 6.982 NM_014347
ZNF324
zinc finger protein 324
chr19_+_59070557 6.960 LOC100131691
uncharacterized LOC100131691
chr3_-_47517316 6.925 SCAP
SREBF chaperone
chr3_+_14444083 6.902 NM_001134367
NM_001134368
NM_003043
SLC6A6


solute carrier family 6 (neurotransmitter transporter, taurine), member 6


chr7_+_158649200 6.869 NM_018051
WDR60
WD repeat domain 60
chr19_-_55919324 6.861 NM_014501
UBE2S
ubiquitin-conjugating enzyme E2S
chr19_-_40023449 6.851 NM_152361
EID2B
EP300 interacting inhibitor of differentiation 2B
chr19_+_45147180 6.850 PVR
poliovirus receptor
chr11_+_76092336 6.826 LOC100506127
putative uncharacterized protein FLJ37770-like
chr19_+_45147207 6.777 PVR
poliovirus receptor
chr14_-_23058114 6.716 NM_001344
DAD1
defender against cell death 1
chr17_-_47439326 6.697 NM_001145365
NM_014897
ZNF652

zinc finger protein 652

chrX_-_153707217 6.691 LAGE3
L antigen family, member 3
chr5_+_142150291 6.683 NM_001135608
NM_015071
ARHGAP26

Rho GTPase activating protein 26

chr9_+_134378324 6.677 POMT1
protein-O-mannosyltransferase 1
chr12_+_124457568 6.670 NM_001204299
NM_001204298
NM_152437
ZNF664-FAM101A
ZNF664

protein FAM101A
zinc finger protein 664

chr15_+_67813466 6.606 NM_001143936
C15orf61
chromosome 15 open reading frame 61
chr7_-_150973819 6.599 NM_001003802
SMARCD3
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr19_+_47634177 6.599 SAE1
SUMO1 activating enzyme subunit 1
chr7_-_100808832 6.562 NM_003378
VGF
VGF nerve growth factor inducible
chr7_-_44621784 6.549 TMED4
transmembrane emp24 protein transport domain containing 4
chr7_-_108096693 6.528 NM_001193582
NM_001193583
NM_001193584
NM_005010
NRCAM



neuronal cell adhesion molecule



chr14_-_23058062 6.527 DAD1
defender against cell death 1
chr4_-_141348760 6.526 NM_001130675
NM_004362
CLGN

calmegin

chr17_-_26733185 6.512 NM_001242366
NM_080669
SLC46A1

solute carrier family 46 (folate transporter), member 1

chr16_-_4166185 6.499 NM_001116
ADCY9
adenylate cyclase 9
chr19_+_47634148 6.485 SAE1
SUMO1 activating enzyme subunit 1
chr17_+_77751929 6.475 NM_005189
NM_032647
CBX2

chromobox homolog 2

chr19_-_45873641 6.459 ERCC2
excision repair cross-complementing rodent repair deficiency, complementation group 2
chr19_+_47634044 6.444 NM_001145713
NM_001145714
NM_005500
SAE1


SUMO1 activating enzyme subunit 1


chr18_+_10526095 6.429 NAPG
N-ethylmaleimide-sensitive factor attachment protein, gamma
chr16_-_70713927 6.419 MTSS1L
metastasis suppressor 1-like
chr14_+_65879694 6.388 FUT8
fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
chr5_-_1594617 6.378 SDHAP3
succinate dehydrogenase complex, subunit A, flavoprotein pseudogene 3
chr19_+_18451365 6.367 NM_017712
PGPEP1
pyroglutamyl-peptidase I
chr1_-_3773620 6.326 CEP104
centrosomal protein 104kDa
chrX_+_38420690 6.326 NM_004615
TSPAN7
tetraspanin 7
chr19_+_45147090 6.309 NM_001135768
NM_001135769
NM_001135770
NM_006505
PVR



poliovirus receptor



chr5_+_218441 6.254 SDHA
succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
chr8_+_42249383 6.216 VDAC3
voltage-dependent anion channel 3
chr13_-_21348081 6.213 N6AMT2
N-6 adenine-specific DNA methyltransferase 2 (putative)
chr10_-_16859408 6.212 NM_012425
NM_152724
RSU1

Ras suppressor protein 1

chr19_+_47634133 6.198 SAE1
SUMO1 activating enzyme subunit 1
chr18_+_10526044 6.193 NAPG
N-ethylmaleimide-sensitive factor attachment protein, gamma
chr9_+_134378353 6.188 POMT1
protein-O-mannosyltransferase 1
chr19_-_45004482 6.179 NM_013256
ZNF180
zinc finger protein 180
chr13_+_35516390 6.176 NM_015678
NBEA
neurobeachin
chr19_+_39421347 6.152 NM_033362
MRPS12
mitochondrial ribosomal protein S12
chr19_+_41107220 6.150 NM_001042545
LTBP4
latent transforming growth factor beta binding protein 4
chr9_-_139940464 6.125 NPDC1
neural proliferation, differentiation and control, 1
chr18_+_10525861 6.123 NM_003826
NAPG
N-ethylmaleimide-sensitive factor attachment protein, gamma
chr9_-_139940556 6.079 NPDC1
neural proliferation, differentiation and control, 1
chr19_+_47634118 6.076 SAE1
SUMO1 activating enzyme subunit 1
chr19_-_39926535 6.028 NM_001020
RPS16
ribosomal protein S16
chr16_-_71917880 6.019 NM_001201552
NM_001201554
NM_001201556
ZNF821


zinc finger protein 821


chr8_+_26435590 5.990 DPYSL2
dihydropyrimidinase-like 2
chr19_-_45873839 5.974 NM_000400
NM_001130867
ERCC2

excision repair cross-complementing rodent repair deficiency, complementation group 2

chr3_-_48647085 5.950 NM_003365
UQCRC1
ubiquinol-cytochrome c reductase core protein I
chr19_-_59069747 5.940 UBE2M
ubiquitin-conjugating enzyme E2M
chr16_+_50099880 5.927 NM_182922
HEATR3
HEAT repeat containing 3
chr8_-_145752405 5.881 NM_001024678
LRRC24
leucine rich repeat containing 24
chr3_-_48647052 5.859 UQCRC1
ubiquinol-cytochrome c reductase core protein I
chr19_+_2328628 5.851 NM_001077238
NM_152988
SPPL2B

signal peptide peptidase-like 2B

chr3_+_195384918 5.842 SDHAP1
SDHAP2
succinate dehydrogenase complex, subunit A, flavoprotein pseudogene 1
succinate dehydrogenase complex, subunit A, flavoprotein pseudogene 2
chr19_-_40791291 5.840 NM_001243027
NM_001243028
NM_001626
AKT2


v-akt murine thymoma viral oncogene homolog 2


chr19_+_2328679 5.821 SPPL2B
signal peptide peptidase-like 2B

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
1.46 2.17e-19 GO:0044260 cellular macromolecule metabolic process
1.34 1.60e-17 GO:0044237 cellular metabolic process
1.37 2.11e-14 GO:0043170 macromolecule metabolic process
1.28 2.33e-14 GO:0008152 metabolic process
1.69 1.08e-13 GO:0010467 gene expression
1.28 1.13e-11 GO:0044238 primary metabolic process
1.52 5.34e-11 GO:0044267 cellular protein metabolic process
1.47 2.57e-10 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.54 3.21e-10 GO:0090304 nucleic acid metabolic process
1.61 1.51e-09 GO:0016070 RNA metabolic process
2.58 2.71e-09 GO:0006412 translation
1.40 8.74e-09 GO:0034641 cellular nitrogen compound metabolic process
1.39 1.15e-08 GO:0006807 nitrogen compound metabolic process
3.77 1.77e-07 GO:0022904 respiratory electron transport chain
1.55 2.51e-07 GO:0034645 cellular macromolecule biosynthetic process
3.32 2.76e-07 GO:0045333 cellular respiration
1.54 4.15e-07 GO:0009059 macromolecule biosynthetic process
1.37 1.28e-06 GO:0019538 protein metabolic process
1.40 9.98e-06 GO:0044249 cellular biosynthetic process
2.98 1.84e-05 GO:0022900 electron transport chain
1.83 2.23e-05 GO:0006396 RNA processing
1.90 4.16e-05 GO:0016071 mRNA metabolic process
1.37 7.11e-05 GO:0009058 biosynthetic process
1.68 3.10e-04 GO:0046907 intracellular transport
1.62 6.43e-04 GO:0045184 establishment of protein localization
1.62 8.43e-04 GO:0015031 protein transport
1.52 2.30e-03 GO:0008104 protein localization
2.04 2.38e-03 GO:0008380 RNA splicing
2.08 3.56e-03 GO:0015980 energy derivation by oxidation of organic compounds
3.78 4.56e-03 GO:0006119 oxidative phosphorylation
1.88 5.56e-03 GO:0006397 mRNA processing
2.72 1.84e-02 GO:0006414 translational elongation
1.81 1.96e-02 GO:0006091 generation of precursor metabolites and energy
2.25 1.97e-02 GO:0006913 nucleocytoplasmic transport
2.22 2.54e-02 GO:0051169 nuclear transport
2.00 2.71e-02 GO:0016567 protein ubiquitination
3.68 2.78e-02 GO:0042773 ATP synthesis coupled electron transport
3.68 2.78e-02 GO:0042775 mitochondrial ATP synthesis coupled electron transport
3.06 3.02e-02 GO:0006200 ATP catabolic process
1.68 3.02e-02 GO:0044265 cellular macromolecule catabolic process
1.95 3.24e-02 GO:0032446 protein modification by small protein conjugation
1.08 3.74e-02 GO:0009987 cellular process

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
1.34 1.00e-38 GO:0043231 intracellular membrane-bounded organelle
1.23 1.65e-38 GO:0005622 intracellular
1.34 1.78e-38 GO:0043227 membrane-bounded organelle
1.24 5.67e-38 GO:0044424 intracellular part
1.28 3.21e-33 GO:0043229 intracellular organelle
1.28 8.18e-33 GO:0043226 organelle
1.40 1.01e-21 GO:0005634 nucleus
1.26 1.51e-18 GO:0005737 cytoplasm
1.36 1.49e-17 GO:0044446 intracellular organelle part
1.89 3.31e-17 GO:0005739 mitochondrion
1.35 4.27e-17 GO:0044422 organelle part
4.34 1.39e-15 GO:0044455 mitochondrial membrane part
1.57 8.49e-13 GO:0070013 intracellular organelle lumen
1.55 1.61e-12 GO:0031974 membrane-enclosed lumen
2.09 6.31e-12 GO:0044429 mitochondrial part
1.28 8.07e-12 GO:0044444 cytoplasmic part
1.53 1.10e-11 GO:0043233 organelle lumen
1.53 7.37e-11 GO:0044428 nuclear part
1.37 9.57e-10 GO:0032991 macromolecular complex
1.51 5.90e-08 GO:0031981 nuclear lumen
2.37 7.60e-08 GO:0005743 mitochondrial inner membrane
4.21 2.11e-07 GO:0070469 respiratory chain
1.59 2.17e-07 GO:0005654 nucleoplasm
2.05 3.32e-07 GO:0005740 mitochondrial envelope
2.21 1.03e-06 GO:0019866 organelle inner membrane
4.18 1.33e-06 GO:0005746 mitochondrial respiratory chain
2.04 1.34e-06 GO:0031966 mitochondrial membrane
1.77 4.32e-06 GO:0031967 organelle envelope
1.74 1.10e-05 GO:0031975 envelope
1.31 6.95e-05 GO:0043234 protein complex
1.82 8.27e-05 GO:0030529 ribonucleoprotein complex
1.38 8.67e-05 GO:0005829 cytosol
2.13 3.46e-04 GO:0005759 mitochondrial matrix
1.62 7.80e-04 GO:0044451 nucleoplasm part
1.34 1.04e-03 GO:0031090 organelle membrane
4.16 1.07e-03 GO:0005747 mitochondrial respiratory chain complex I
4.16 1.07e-03 GO:0030964 NADH dehydrogenase complex
4.16 1.07e-03 GO:0045271 respiratory chain complex I
6.17 5.11e-03 GO:0032592 integral to mitochondrial membrane
3.67 1.15e-02 GO:0008287 protein serine/threonine phosphatase complex
2.78 1.48e-02 GO:0031461 cullin-RING ubiquitin ligase complex
2.10 1.64e-02 GO:0005840 ribosome
1.04 1.64e-02 GO:0044464 cell part
5.45 1.65e-02 GO:0005753 mitochondrial proton-transporting ATP synthase complex
1.04 1.68e-02 GO:0005623 cell
2.82 2.01e-02 GO:0016591 DNA-directed RNA polymerase II, holoenzyme
2.25 2.39e-02 GO:0000151 ubiquitin ligase complex
4.87 4.37e-02 GO:0045259 proton-transporting ATP synthase complex

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
1.87 1.93e-09 GO:0003723 RNA binding
1.38 5.02e-09 GO:0003676 nucleic acid binding
1.21 1.34e-08 GO:0005515 protein binding
1.24 4.25e-07 GO:0003824 catalytic activity
1.10 7.46e-06 GO:0005488 binding
1.34 2.88e-04 GO:0000166 nucleotide binding
1.76 2.36e-03 GO:0016874 ligase activity
3.76 1.19e-02 GO:0003899 DNA-directed RNA polymerase activity
3.76 1.19e-02 GO:0034062 RNA polymerase activity
3.75 2.53e-02 GO:0003954 NADH dehydrogenase activity
3.75 2.53e-02 GO:0008137 NADH dehydrogenase (ubiquinone) activity
3.75 2.53e-02 GO:0050136 NADH dehydrogenase (quinone) activity
2.21 3.53e-02 GO:0003735 structural constituent of ribosome
1.27 3.60e-02 GO:0003677 DNA binding
2.51 4.35e-02 GO:0015078 hydrogen ion transmembrane transporter activity