Motif ID: NR6A1.p2

Z-value: 0.483


Transcription factors associated with NR6A1.p2:

Gene SymbolEntrez IDGene Name
NR6A1 2649 nuclear receptor subfamily 6, group A, member 1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
NR6A1hg19_v1_chr9_-_127533397_127533624-0.094.4e-01Click!


Activity profile for motif NR6A1.p2.

activity profile for motif NR6A1.p2


Sorted Z-values histogram for motif NR6A1.p2

Sorted Z-values for motif NR6A1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NR6A1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr19_-_6720585 10.271 NM_000064
C3
complement component 3
chr12_+_7169192 4.590


chr15_+_101420004 4.065 NM_000693
ALDH1A3
aldehyde dehydrogenase 1 family, member A3
chr15_+_101420032 2.751 ALDH1A3
aldehyde dehydrogenase 1 family, member A3
chr11_+_36317724 2.335 NM_001160167
PRR5L
proline rich 5 like
chr7_+_100199881 1.975 NM_002593
PCOLCE
procollagen C-endopeptidase enhancer
chr11_-_108464344 1.646 NM_015065
EXPH5
exophilin 5
chr10_+_89419352 1.412 NM_001015880
NM_004670
PAPSS2

3'-phosphoadenosine 5'-phosphosulfate synthase 2

chr10_-_71892514 1.250 AIFM2
apoptosis-inducing factor, mitochondrion-associated, 2
chr4_+_41614725 1.230 LIMCH1
LIM and calponin homology domains 1
chr1_-_159825136 1.169 NM_001134233
C1orf204
chromosome 1 open reading frame 204
chr9_-_14313509 1.099 NFIB
nuclear factor I/B
chr10_-_126107493 1.076 NM_000274
NM_001171814
OAT

ornithine aminotransferase

chr1_-_29309092 1.030


chr9_-_14314036 0.977 NM_001190737
NM_005596
NFIB

nuclear factor I/B

chr6_-_133035180 0.779 NM_004666
VNN1
vanin 1
chr9_-_14313899 0.757 NFIB
nuclear factor I/B
chr20_-_3149070 0.700 NM_014731
ProSAPiP1
ProSAPiP1 protein
chr10_+_81107259 0.690 PPIF
peptidylprolyl isomerase F
chr12_-_58135853 0.666 NM_014770
AGAP2
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chr9_+_35792405 0.664 NM_003995
NPR2
natriuretic peptide receptor B/guanylate cyclase B (atrionatriuretic peptide receptor B)
chr6_+_129204285 0.663 NM_000426
NM_001079823
LAMA2

laminin, alpha 2

chr5_-_65017874 0.661 NM_019072
SGTB
small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta
chr14_-_58893867 0.656 TIMM9
translocase of inner mitochondrial membrane 9 homolog (yeast)
chr3_-_148804122 0.637 NM_003071
NM_139048
HLTF

helicase-like transcription factor

chr20_+_57264186 0.630 NM_001204872
NM_001204873
NPEPL1

aminopeptidase-like 1

chr12_-_7261788 0.627 NM_016546
C1RL
complement component 1, r subcomponent-like
chr6_+_43028181 0.623 NM_201522
KLC4
kinesin light chain 4
chr10_-_71892596 0.619 NM_001198696
NM_032797
AIFM2

apoptosis-inducing factor, mitochondrion-associated, 2

chr6_+_31973358 0.561 NM_000500
NM_001128590
CYP21A2

cytochrome P450, family 21, subfamily A, polypeptide 2

chr6_-_33547833 0.471 BAK1
BCL2-antagonist/killer 1
chr7_+_63773185 0.460 NM_001170905
ZNF736
zinc finger protein 736
chrX_-_138724851 0.422 NM_001171877
NM_001171878
NM_001171879
NM_005369
MCF2



MCF.2 cell line derived transforming sequence



chr10_+_106013951 0.420 NM_001191003
GSTO1
glutathione S-transferase omega 1
chr17_+_74075262 0.419 NM_180990
ZACN
zinc activated ligand-gated ion channel
chr9_-_14313943 0.415 NFIB
nuclear factor I/B
chr10_-_126107454 0.395 OAT
ornithine aminotransferase
chr1_+_9299902 0.386 H6PD
hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
chr10_+_81107242 0.381 PPIF
peptidylprolyl isomerase F
chr8_+_142432006 0.376 NM_007079
NM_032611
PTP4A3

protein tyrosine phosphatase type IVA, member 3

chr7_+_1577118 0.370 MAFK
v-maf musculoaponeurotic fibrosarcoma oncogene homolog K (avian)
chr9_-_114247024 0.359 NM_001080398
KIAA0368
KIAA0368
chr2_+_18059923 0.356 NM_002252
KCNS3
potassium voltage-gated channel, delayed-rectifier, subfamily S, member 3
chr11_+_35684342 0.351 NM_017583
TRIM44
tripartite motif containing 44
chr1_+_212738675 0.348 NM_001030287
ATF3
activating transcription factor 3
chr16_+_1386197 0.347 NM_001199096
BAIAP3
BAI1-associated protein 3
chr3_+_186383770 0.341 NM_000412
HRG
histidine-rich glycoprotein
chr1_+_197886499 0.328 NM_020204
LHX9
LIM homeobox 9
chr2_-_224903324 0.306 NM_001136530
SERPINE2
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
chr19_-_46974789 0.303 NM_001103149
NM_018215
PNMAL1

PNMA-like 1

chr1_-_40236926 0.301 NM_022120
OXCT2
3-oxoacid CoA transferase 2
chr2_+_95963026 0.300 NM_013434
KCNIP3
Kv channel interacting protein 3, calsenilin
chr11_+_65192284 0.295 NEAT1
nuclear paraspeckle assembly transcript 1 (non-protein coding)
chr12_-_6484389 0.292 NM_001159576
SCNN1A
sodium channel, nonvoltage-gated 1 alpha
chr19_-_2717272 0.288 DIRAS1
DIRAS family, GTP-binding RAS-like 1
chr4_-_89205667 0.287 PPM1K
protein phosphatase, Mg2+/Mn2+ dependent, 1K
chr1_+_93300359 0.281 RPL5
ribosomal protein L5
chr11_+_35684418 0.280 TRIM44
tripartite motif containing 44
chr10_+_123754141 0.279 TACC2
transforming, acidic coiled-coil containing protein 2
chr8_-_53626991 0.272 NM_001083617
NM_014781
RB1CC1

RB1-inducible coiled-coil 1

chr3_-_139396773 0.266 NM_001200047
NM_178177
NMNAT3

nicotinamide nucleotide adenylyltransferase 3

chr1_+_45274153 0.247 NM_001136537
BTBD19
BTB (POZ) domain containing 19
chrX_-_44402088 0.239 NM_173794
FUNDC1
FUN14 domain containing 1
chr7_+_26403944 0.238 NM_001199838
SNX10
sorting nexin 10
chr13_-_42535066 0.234 KIAA0564
KIAA0564
chr12_+_116997185 0.233 NM_001085481
MAP1LC3B2
microtubule-associated protein 1 light chain 3 beta 2
chr8_-_145018057 0.217 NM_201382
PLEC
plectin
chr1_-_20834516 0.211 MUL1
mitochondrial E3 ubiquitin protein ligase 1
chr3_-_157213138 0.206 NM_001167917
VEPH1
ventricular zone expressed PH domain homolog 1 (zebrafish)
chr7_-_87936202 0.206 NM_001205315
NM_001205316
NM_024636
STEAP4


STEAP family member 4


chr16_+_30676098 0.203 FBRS
fibrosin
chr15_-_41166336 0.201 NM_133639
RHOV
ras homolog gene family, member V
chr7_-_65447233 0.198 NM_000181
GUSB
glucuronidase, beta
chr3_-_14989857 0.195 LOC100505641
uncharacterized LOC100505641
chr1_-_207224298 0.190 NM_018566
YOD1
YOD1 OTU deubiquinating enzyme 1 homolog (S. cerevisiae)
chr6_+_155411422 0.188 NM_012454
TIAM2
T-cell lymphoma invasion and metastasis 2
chr1_+_113236679 0.182 MOV10
Mov10, Moloney leukemia virus 10, homolog (mouse)
chr1_-_20834609 0.180 NM_024544
MUL1
mitochondrial E3 ubiquitin protein ligase 1
chr2_+_33172368 0.178 NM_206943
LTBP1
latent transforming growth factor beta binding protein 1
chr7_+_73868111 0.170 NM_001199207
NM_005685
NM_016328
GTF2IRD1


GTF2I repeat domain containing 1


chr14_-_47120940 0.168 NM_080746
RPL10L
ribosomal protein L10-like
chr19_+_10196972 0.159 C19orf66
chromosome 19 open reading frame 66
chr15_+_89739234 0.154 ABHD2
abhydrolase domain containing 2
chr12_-_10562142 0.151 NM_013431
KLRC4-KLRK1
KLRC4
KLRC4-KLRK1 readthrough
killer cell lectin-like receptor subfamily C, member 4
chr16_-_28222700 0.148 XPO6
exportin 6
chr16_+_56642477 0.144 NM_005953
MT2A
metallothionein 2A
chr1_+_40997232 0.140 NM_152373
ZNF684
zinc finger protein 684
chr9_+_139981338 0.138 MAN1B1
mannosidase, alpha, class 1B, member 1
chr1_-_16134192 0.137 NM_001089591
UQCRHL
ubiquinol-cytochrome c reductase hinge protein-like
chr18_+_33767420 0.134 NM_017947
MOCOS
molybdenum cofactor sulfurase
chr7_-_65447206 0.130 GUSB
glucuronidase, beta
chr7_+_73868236 0.123 GTF2IRD1
GTF2I repeat domain containing 1
chr1_+_76190042 0.119 NM_000016
NM_001127328
ACADM

acyl-CoA dehydrogenase, C-4 to C-12 straight chain

chr7_-_65447162 0.114 GUSB
glucuronidase, beta
chr1_+_219347195 0.113 LYPLAL1
lysophospholipase-like 1
chr10_+_51837885 0.112 NM_018232
FAM21B
family with sequence similarity 21, member B
chr3_-_138478184 0.112 NM_006219
PIK3CB
phosphoinositide-3-kinase, catalytic, beta polypeptide
chr12_+_54410893 0.111 HOXC5
HOXC6
homeobox C5
homeobox C6
chr1_+_219347123 0.109 NM_138794
LYPLAL1
lysophospholipase-like 1
chr6_-_30899926 0.109 NM_205854
SFTA2
surfactant associated 2
chr12_+_108956293 0.105 NM_014301
NM_213595
ISCU

iron-sulfur cluster scaffold homolog (E. coli)

chr11_-_796175 0.104 NM_024698
SLC25A22
solute carrier family 25 (mitochondrial carrier: glutamate), member 22
chr11_+_111957533 0.102 NM_003002
SDHD
succinate dehydrogenase complex, subunit D, integral membrane protein
chr19_-_5846465 0.101 FUT3
fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group)
chr19_+_10197023 0.101 C19orf66
chromosome 19 open reading frame 66
chr16_-_420508 0.098 NM_006428
MRPL28
mitochondrial ribosomal protein L28
chr22_-_24059524 0.095 GUSBP11
glucuronidase, beta pseudogene 11
chr1_+_36387788 0.094 EIF2C1
eukaryotic translation initiation factor 2C, 1
chr11_+_118754474 0.089 NM_001716
CXCR5
chemokine (C-X-C motif) receptor 5
chr21_+_33765411 0.086 C21orf119
chromosome 21 open reading frame 119
chr1_+_6684924 0.084 NM_001195753
THAP3
THAP domain containing, apoptosis associated protein 3
chr9_-_114362100 0.083 NM_001146108
NM_001146109
PTGR1

prostaglandin reductase 1

chr8_-_145701139 0.077 FOXH1
forkhead box H1
chr11_+_30344645 0.073 NM_152316
C11orf46
chromosome 11 open reading frame 46
chr1_-_120612260 0.073 NOTCH2
notch 2
chr14_-_73453651 0.071 NM_178441
ZFYVE1
zinc finger, FYVE domain containing 1
chr10_+_47894022 0.071 NM_018232
FAM21B
family with sequence similarity 21, member B
chr6_-_43484503 0.069 YIPF3
Yip1 domain family, member 3
chr10_+_106014467 0.068 NM_001191002
NM_004832
GSTO1

glutathione S-transferase omega 1

chr5_+_43603312 0.067 NNT
nicotinamide nucleotide transhydrogenase
chr1_-_120612175 0.066 NOTCH2
notch 2
chr8_-_145701717 0.065 NM_003923
FOXH1
forkhead box H1
chr14_+_93118793 0.064 RIN3
Ras and Rab interactor 3
chr13_-_28024700 0.063 NM_001166263
NM_152912
MTIF3

mitochondrial translational initiation factor 3

chr1_+_145209067 0.059 NM_203458
NOTCH2NL
notch 2 N-terminal like
chr2_+_24150144 0.058 UBXN2A
UBX domain protein 2A
chr14_+_93118576 0.057 RIN3
Ras and Rab interactor 3
chr17_+_75446735 0.054 SEPT9
septin 9
chr19_-_43709692 0.053 NM_002780
NM_213633
PSG4

pregnancy specific beta-1-glycoprotein 4

chr16_+_31494438 0.050 NM_003041
SLC5A2
solute carrier family 5 (sodium/glucose cotransporter), member 2
chr1_+_152769226 0.050 NM_178352
LCE1D
late cornified envelope 1D
chr6_+_84743250 0.050 NM_138409
MRAP2
melanocortin 2 receptor accessory protein 2
chr6_+_117803779 0.049 NM_173674
DCBLD1
discoidin, CUB and LCCL domain containing 1
chr6_-_43484701 0.048 NM_015388
YIPF3
Yip1 domain family, member 3
chr11_+_111957611 0.048 SDHD
succinate dehydrogenase complex, subunit D, integral membrane protein
chr1_-_147624436 0.045 NM_183372
NBPF11
neuroblastoma breakpoint family, member 11
chr5_-_60458228 0.039 NM_001048249
C5orf43
chromosome 5 open reading frame 43
chr22_-_24059502 0.037 GUSBP11
glucuronidase, beta pseudogene 11
chr11_-_62472901 0.035


chr7_+_56032065 0.035 NM_001202469
NM_001483
GBAS

glioblastoma amplified sequence

chr11_+_66624501 0.034 LRFN4
leucine rich repeat and fibronectin type III domain containing 4
chr1_+_26503973 0.033 NM_006314
CNKSR1
connector enhancer of kinase suppressor of Ras 1
chr9_-_135230129 0.032 SETX
senataxin
chr1_+_19923457 0.029 NM_001204088
NM_001204089
NM_001032363
NM_001204082
NM_001204083
C1orf151-NBL1

MINOS1


C1orf151-NBL1 readthrough

mitochondrial inner membrane organizing system 1


chr1_-_935469 0.026 NM_001142467
NM_021170
HES4

hairy and enhancer of split 4 (Drosophila)

chr16_+_3451154 0.025 NM_001032292
NM_003450
ZNF174

zinc finger protein 174

chr6_-_26032287 0.025 NM_003537
HIST1H3B
histone cluster 1, H3b
chr17_-_62009620 0.022 NM_000626
NM_001039933
NM_021602
CD79B


CD79b molecule, immunoglobulin-associated beta


chr19_+_45394642 0.022 TOMM40
translocase of outer mitochondrial membrane 40 homolog (yeast)
chr14_+_89029371 0.019 ZC3H14
zinc finger CCCH-type containing 14
chrY_-_1460901 0.018 NM_001636
SLC25A6
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6
chr8_-_145690737 0.018 NM_032687
NM_001129888
CYHR1

cysteine/histidine-rich 1

chr1_+_40420802 0.016 MFSD2A
major facilitator superfamily domain containing 2A
chr3_-_38178463 0.013 ACAA1
acetyl-CoA acyltransferase 1
chr12_+_125811161 0.008 NM_052907
TMEM132B
transmembrane protein 132B
chr9_-_135230358 0.007 NM_015046
SETX
senataxin
chr17_-_47925378 0.003 NM_001077503
NM_001077504
NM_001077505
NM_001077506
NM_170685
TAC4




tachykinin 4 (hemokinin)




chr22_+_32010152 0.002 SFI1
Sfi1 homolog, spindle assembly associated (yeast)

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.