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Motif ID: NHLH1,2.p2

Z-value: 1.166

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr4_-_57976550	12.963	NM_001253835 NM_001553	IGFBP7	insulin-like growth factor binding protein 7
chr4_-_57976516	11.549		IGFBP7	insulin-like growth factor binding protein 7
chr10_+_17271277	7.898		VIM	vimentin
chr10_+_17271276	7.790		VIM	vimentin
chr10_+_17271341	7.633		VIM	vimentin
chr10_+_17271302	7.134		VIM	vimentin
chr17_+_80693398	6.204	NM_022158	FN3K	fructosamine 3 kinase
chr2_+_37571752	6.083	NM_012413	QPCT	glutaminyl-peptide cyclotransferase
chr9_-_86153048	5.852	NM_001244959 NM_174938	FRMD3	FERM domain containing 3
chr11_-_125366048	5.838	NM_005103 NM_022549	FEZ1	fasciculation and elongation protein zeta 1 (zygin I)
chr1_+_10057254	5.498	NM_052960	RBP7	retinol binding protein 7, cellular
chr2_-_1748240	4.717		PXDN	peroxidasin homolog (Drosophila)
chr2_-_130902568	4.660	NM_207310	CCDC74B	coiled-coil domain containing 74B
chr19_+_35521591	4.570	NM_001037 NM_199037	SCN1B	sodium channel, voltage-gated, type I, beta
chr5_+_129240453	4.480	NM_175856	CHSY3	chondroitin sulfate synthase 3
chr8_+_72756218	4.419		LOC100132891	uncharacterized LOC100132891
chr19_+_4304590	4.278	NM_024333	FSD1	fibronectin type III and SPRY domain containing 1
chr7_-_142985270	4.162
chr19_+_52873169	4.159	NM_001145434	ZNF880	zinc finger protein 880
chr4_+_74735107	4.151	NM_001511	CXCL1	chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
chr19_-_46974789	3.980	NM_001103149 NM_018215	PNMAL1	PNMA-like 1
chr4_-_99579540	3.913	NM_005723	TSPAN5	tetraspanin 5
chr12_-_71003622	3.748	NM_001206971 NM_001206972 NM_002837	PTPRB	protein tyrosine phosphatase, receptor type, B
chr10_-_62703822	3.683	NM_001242359 NM_014836	RHOBTB1	Rho-related BTB domain containing 1
chr22_-_20137430	3.592	NM_001243537	LOC388849	uncharacterized LOC388849
chr19_-_46974663	3.573		PNMAL1	PNMA-like 1
chr17_-_19770988	3.527	NM_001142610 NM_014683	ULK2	unc-51-like kinase 2 (C. elegans)
chr4_-_57976355	3.506		IGFBP7	insulin-like growth factor binding protein 7
chr6_+_144471631	3.489	NM_003764	STX11	syntaxin 11
chr4_-_83483099	3.465	NM_001080506	TMEM150C	transmembrane protein 150C
chr2_+_101436491	3.461	NM_002518	NPAS2	neuronal PAS domain protein 2
chr19_+_48828627	3.429	NM_001425	EMP3	epithelial membrane protein 3
chrX_+_55478537	3.398	NM_014061	MAGEH1	melanoma antigen family H, 1
chrX_-_38079980	3.390	NM_001170750 NM_001170751 NM_001170752 NM_006307	SRPX	sushi-repeat containing protein, X-linked
chr17_+_38171613	3.375	NM_000759 NM_001178147 NM_172219 NM_172220	CSF3	colony stimulating factor 3 (granulocyte)
chr19_-_19006868	3.359	NM_021267 NM_198207 NM_001492	CERS1 GDF1	ceramide synthase 1 growth differentiation factor 1
chr6_-_18122850	3.328	NM_198586	NHLRC1	NHL repeat containing 1
chr19_+_48828820	3.316		EMP3	epithelial membrane protein 3
chr5_+_137774632	3.239	NM_016606	REEP2	receptor accessory protein 2
chr11_-_63933204	3.225		MACROD1	MACRO domain containing 1
chr11_-_119187811	3.223	NM_006500	MCAM	melanoma cell adhesion molecule
chr8_+_17014006	3.132		ZDHHC2	zinc finger, DHHC-type containing 2
chr1_+_154298034	3.101	NM_001005855	ATP8B2	ATPase, class I, type 8B, member 2
chr2_-_227663454	3.071	NM_005544	IRS1	insulin receptor substrate 1
chr1_+_90098624	3.060		LRRC8C	leucine rich repeat containing 8 family, member C
chrX_-_48693934	2.999	NM_013271	PCSK1N	proprotein convertase subtilisin/kexin type 1 inhibitor
chr1_-_85358851	2.988	NM_012152	LPAR3	lysophosphatidic acid receptor 3
chr14_-_94854910	2.974		SERPINA1	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr2_+_228029280	2.957	NM_000091	COL4A3	collagen, type IV, alpha 3 (Goodpasture antigen)
chr6_-_105584982	2.946	NM_001199563	BVES	blood vessel epicardial substance
chr3_+_159943628	2.922		C3orf80	chromosome 3 open reading frame 80
chr11_+_118401755	2.894	NM_001144034 NM_001144035 NM_001144036 NM_001144037 NM_001144038 NM_032780	TMEM25	transmembrane protein 25
chr8_+_99076749	2.888	NM_001170806 NM_173549	C8orf47	chromosome 8 open reading frame 47
chr3_-_133614296	2.873		RAB6B	RAB6B, member RAS oncogene family
chr2_-_216300444	2.838		FN1	fibronectin 1
chr11_-_63933493	2.827	NM_014067	MACROD1	MACRO domain containing 1
chr22_+_21738039	2.797	NM_001128635	RIMBP3B	RIMS binding protein 3B
chr1_+_154298026	2.768		ATP8B2	ATPase, class I, type 8B, member 2
chr19_+_41699140	2.766		CYP2S1	cytochrome P450, family 2, subfamily S, polypeptide 1
chrX_+_51075667	2.761		NUDT10	nudix (nucleoside diphosphate linked moiety X)-type motif 10
chr19_+_12949258	2.733	NM_014975	MAST1	microtubule associated serine/threonine kinase 1
chr6_+_31895401	2.722		C2	complement component 2
chr8_+_72756335	2.713
chr13_-_96296919	2.701	NM_014934 NM_198968	DZIP1	DAZ interacting protein 1
chr2_-_1748285	2.679	NM_012293	PXDN	peroxidasin homolog (Drosophila)
chr12_+_569542	2.614	NM_173593	B4GALNT3	beta-1,4-N-acetyl-galactosaminyl transferase 3
chr15_-_40600118	2.592	NM_004573	PLCB2	phospholipase C, beta 2
chr11_-_66335958	2.589	NM_003793	CTSF	cathepsin F
chr12_+_53491417	2.584	NM_002178	IGFBP6	insulin-like growth factor binding protein 6
chr15_-_40600025	2.580		PLCB2	phospholipase C, beta 2
chr2_-_1748317	2.578		PXDN	peroxidasin homolog (Drosophila)
chrX_-_154114431	2.557	NM_019863	F8	coagulation factor VIII, procoagulant component
chr14_-_61115906	2.555	NM_005982	SIX1	SIX homeobox 1
chr2_-_230135954	2.506	NM_001100818 NM_017933	PID1	phosphotyrosine interaction domain containing 1
chr4_+_81187741	2.497	NM_004464 NM_033143	FGF5	fibroblast growth factor 5
chr1_+_111889194	2.476	NM_181643	C1orf88	chromosome 1 open reading frame 88
chr1_-_94703252	2.476	NM_004815	ARHGAP29	Rho GTPase activating protein 29
chr8_-_23712297	2.450	NM_003155	STC1	stanniocalcin 1
chr19_+_7580987	2.436	NM_018083	ZNF358	zinc finger protein 358
chr20_-_1165116	2.433	NM_018354	TMEM74B	transmembrane protein 74B
chr22_-_21905372	2.427	NM_001128635	RIMBP3B	RIMS binding protein 3B
chr1_+_233749749	2.427	NM_002245	KCNK1	potassium channel, subfamily K, member 1
chrX_+_135229536	2.419	NM_001159702 NM_001159703 NM_001449	FHL1	four and a half LIM domains 1
chr5_+_52776479	2.400		FST	follistatin
chr15_+_25200069	2.328	NM_003097 NM_022804 NM_005678	SNRPN SNURF	small nuclear ribonucleoprotein polypeptide N SNRPN upstream reading frame
chr1_-_1535446	2.295	NM_001242659	LOC643988	uncharacterized LOC643988
chr1_+_90098643	2.294	NM_032270	LRRC8C	leucine rich repeat containing 8 family, member C
chr16_+_15528324	2.275	NM_033201	C16orf45	chromosome 16 open reading frame 45
chr12_+_56137063	2.274	NM_005811	GDF11	growth differentiation factor 11
chr16_+_53133063	2.274		CHD9	chromodomain helicase DNA binding protein 9
chr2_+_231577536	2.266	NM_016289	CAB39	calcium binding protein 39
chr3_-_197282805	2.256	NM_004051 NM_203314	BDH1	3-hydroxybutyrate dehydrogenase, type 1
chr16_+_22825806	2.242	NM_006043	HS3ST2	heparan sulfate (glucosamine) 3-O-sulfotransferase 2
chr2_-_1748213	2.241		PXDN	peroxidasin homolog (Drosophila)
chr10_-_17271955	2.228
chr13_+_88324777	2.224	NM_015567	SLITRK5	SLIT and NTRK-like family, member 5
chr3_+_111717585	2.217	NM_001008272 NM_013259	TAGLN3	transgelin 3
chr13_-_41768533	2.213	NM_032138	KBTBD7	kelch repeat and BTB (POZ) domain containing 7
chr12_+_1738411	2.206	NM_032642	WNT5B	wingless-type MMTV integration site family, member 5B
chr7_-_139168408	2.195	NM_198508	KLRG2	killer cell lectin-like receptor subfamily G, member 2
chr4_-_80994183	2.172
chr6_-_105584542	2.165	NM_007073	BVES	blood vessel epicardial substance
chr3_+_111718006	2.158	NM_001008273	TAGLN3	transgelin 3
chr1_+_90098693	2.155		LRRC8C	leucine rich repeat containing 8 family, member C
chr2_+_191745547	2.152		GLS	glutaminase
chr4_-_80993713	2.141		ANTXR2	anthrax toxin receptor 2
chr17_-_40346427	2.136	NM_001142622 NM_001142623 NM_032484	GHDC	GH3 domain containing
chr6_+_122931541	2.130		PKIB	protein kinase (cAMP-dependent, catalytic) inhibitor beta
chr4_-_80994309	2.122	NM_001145794 NM_058172	ANTXR2	anthrax toxin receptor 2
chr18_-_29993195	2.119
chr17_+_26369935	2.117		NLK	nemo-like kinase
chr12_-_69326946	2.095	NM_001005502 NM_198320	CPM	carboxypeptidase M
chr16_+_19179534	2.089	NM_016524	SYT17	synaptotagmin XVII
chr19_+_16187047	2.082	NM_003290	TPM4	tropomyosin 4
chr4_-_122854192	2.082	NM_003305	TRPC3	transient receptor potential cation channel, subfamily C, member 3
chr5_+_71403040	2.073	NM_005909	MAP1B	microtubule-associated protein 1B
chr10_-_44070008	2.064	NM_001099282 NM_001099283 NM_001099284	ZNF239	zinc finger protein 239
chr13_-_41768392	2.059		KBTBD7	kelch repeat and BTB (POZ) domain containing 7
chr12_+_132312917	2.025	NM_016155	MMP17	matrix metallopeptidase 17 (membrane-inserted)
chr14_+_75536298	2.013	NM_001042430 NM_024643	FAM164C	family with sequence similarity 164, member C
chr3_+_8543508	2.013	NM_014583	LMCD1	LIM and cysteine-rich domains 1
chr14_-_103988829	2.003		CKB	creatine kinase, brain
chr17_-_5095131	1.998	NM_032530	ZNF594	zinc finger protein 594
chr1_+_233749917	1.985		KCNK1	potassium channel, subfamily K, member 1
chr10_-_45474210	1.985	NM_007021	C10orf10	chromosome 10 open reading frame 10
chr17_-_27949814	1.984		CORO6	coronin 6
chr22_-_37823503	1.962	NM_052906	ELFN2	extracellular leucine-rich repeat and fibronectin type III domain containing 2
chr7_+_129142319	1.962	NM_001195243	LOC100287482	uncharacterized LOC100287482
chr14_+_90863365	1.962		CALM1	calmodulin 1 (phosphorylase kinase, delta)
chr3_-_133614421	1.961	NM_016577	RAB6B	RAB6B, member RAS oncogene family
chr10_-_44144266	1.957	NM_006973	ZNF32	zinc finger protein 32
chrX_-_119445306	1.940	NM_001104544 NM_001104545 NM_017938	FAM70A	family with sequence similarity 70, member A
chrX_+_16964730	1.930	NM_001080975 NM_004726	REPS2	RALBP1 associated Eps domain containing 2
chr8_-_142238672	1.928	NM_001080431	SLC45A4	solute carrier family 45, member 4
chr11_-_108368918	1.922	NM_153705	KDELC2	KDEL (Lys-Asp-Glu-Leu) containing 2
chr20_-_44519629	1.921	NM_080749	NEURL2	neuralized homolog 2 (Drosophila)
chr5_+_52776263	1.908	NM_006350 NM_013409	FST	follistatin
chr19_+_36359346	1.901	NM_001024807 NM_005166	APLP1	amyloid beta (A4) precursor-like protein 1
chr6_+_160769365	1.898	NM_021977	SLC22A3	solute carrier family 22 (extraneuronal monoamine transporter), member 3
chr1_-_51810693	1.897	NM_001144832	TTC39A	tetratricopeptide repeat domain 39A
chr16_+_4845265	1.896	NM_001253793 NM_001253794	LOC440335	uncharacterized LOC440335
chr17_+_5095364	1.896		LOC100130950	uncharacterized LOC100130950
chr2_-_216878314	1.892	NM_018000	MREG	melanoregulin
chr10_+_17271859	1.883		VIM	vimentin
chr11_-_74022609	1.870	NM_182904	P4HA3	prolyl 4-hydroxylase, alpha polypeptide III
chr15_-_40599872	1.869		PLCB2	phospholipase C, beta 2
chr2_+_182322265	1.866		ITGA4	integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
chr1_-_229694415	1.859	NM_012089	ABCB10	ATP-binding cassette, sub-family B (MDR/TAP), member 10
chr1_-_24194760	1.845	NM_000147	FUCA1	fucosidase, alpha-L- 1, tissue
chr6_-_167040700	1.840	NM_021135	RPS6KA2	ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr1_-_57045129	1.829		PPAP2B	phosphatidic acid phosphatase type 2B
chr14_+_77228940	1.825		VASH1	vasohibin 1
chr5_-_94620277	1.824	NM_024717	MCTP1	multiple C2 domains, transmembrane 1
chr20_+_36531548	1.822		VSTM2L	V-set and transmembrane domain containing 2 like
chr13_-_77460369	1.820		KCTD12	potassium channel tetramerisation domain containing 12
chr16_+_2039945	1.809	NM_004209	SYNGR3	synaptogyrin 3
chr2_+_231577624	1.793		CAB39	calcium binding protein 39
chr11_+_118401873	1.790		TMEM25	transmembrane protein 25
chr21_-_46293598	1.783		PTTG1IP	pituitary tumor-transforming 1 interacting protein
chr8_+_104383701	1.780		CTHRC1	collagen triple helix repeat containing 1
chr21_-_46293561	1.732		PTTG1IP	pituitary tumor-transforming 1 interacting protein
chr9_-_117880411	1.725	NM_002160	TNC	tenascin C
chr21_-_46293609	1.722	NM_004339	PTTG1IP	pituitary tumor-transforming 1 interacting protein
chr2_+_132285469	1.720	NM_138770	CCDC74A	coiled-coil domain containing 74A
chr5_-_1295022	1.716	NM_001193376 NM_198253	TERT	telomerase reverse transcriptase
chr12_+_53491448	1.715		IGFBP6	insulin-like growth factor binding protein 6
chr10_+_17271956	1.715		VIM	vimentin
chr2_+_150187028	1.709	NM_194317	LYPD6	LY6/PLAUR domain containing 6
chr17_-_73266276	1.704	NM_001242500 NM_001242501	MIF4GD	MIF4G domain containing
chr11_-_32457059	1.696	NM_000378 NM_024424 NM_024426	WT1	Wilms tumor 1
chr6_-_89827605	1.695	NM_080743	SRSF12	serine/arginine-rich splicing factor 12
chr2_-_20212408	1.692		MATN3	matrilin 3
chr8_-_79717540	1.692	NM_000880 NM_001199886 NM_001199887 NM_001199888	IL7	interleukin 7
chr20_+_42143045	1.690	NM_015478	L3MBTL1	l(3)mbt-like 1 (Drosophila)
chr2_-_216249682	1.690		FN1	fibronectin 1
chr8_+_17013459	1.679		ZDHHC2	zinc finger, DHHC-type containing 2
chr4_+_124320664	1.677	NM_005841	SPRY1	sprouty homolog 1, antagonist of FGF signaling (Drosophila)
chr6_-_167040659	1.669		RPS6KA2	ribosomal protein S6 kinase, 90kDa, polypeptide 2
chrX_-_154688260	1.652	NM_001007523 NM_001007524 NM_012151	F8A2 F8A3 F8A1	coagulation factor VIII-associated 2 coagulation factor VIII-associated 3 coagulation factor VIII-associated 1
chr5_+_137774897	1.652		REEP2	receptor accessory protein 2
chr1_+_215256559	1.646	NM_001017425 NM_014217	KCNK2	potassium channel, subfamily K, member 2
chr12_+_7023490	1.642	NM_001975	ENO2	enolase 2 (gamma, neuronal)
chr5_-_168727715	1.642	NM_003062	SLIT3	slit homolog 3 (Drosophila)
chr9_+_125133228	1.641	NM_000962 NM_080591	PTGS1	prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr2_-_220436010	1.639		OBSL1	obscurin-like 1
chr8_-_82024277	1.637	NM_018440	PAG1	phosphoprotein associated with glycosphingolipid microdomains 1
chr3_-_53880403	1.631	NM_018397	CHDH	choline dehydrogenase
chr21_-_46293532	1.630		PTTG1IP	pituitary tumor-transforming 1 interacting protein
chr12_-_49463729	1.628	NM_144593	RHEBL1	Ras homolog enriched in brain like 1
chr2_-_19558371	1.623	NM_145260	OSR1	odd-skipped related 1 (Drosophila)
chr14_+_38678280	1.619		SSTR1	somatostatin receptor 1
chr2_+_33359607	1.617	NM_000627 NM_001166264 NM_001166265 NM_001166266	LTBP1	latent transforming growth factor beta binding protein 1
chr10_-_103347882	1.614		POLL	polymerase (DNA directed), lambda
chr19_-_36499583	1.596	NM_001039876	C19orf46	chromosome 19 open reading frame 46
chr6_-_153452383	1.595	NM_012419	RGS17	regulator of G-protein signaling 17
chr12_-_133263988	1.584		POLE	polymerase (DNA directed), epsilon
chr6_+_86159738	1.581		NT5E	5'-nucleotidase, ecto (CD73)
chr19_-_39805975	1.581	NM_020862	LRFN1	leucine rich repeat and fibronectin type III domain containing 1
chr15_-_34659245	1.580	NM_153613	LPCAT4	lysophosphatidylcholine acyltransferase 4
chr3_-_190040192	1.577	NM_021101	CLDN1	claudin 1

Gene overrepresentation in process category:

Enrichment	P-value	GO Accession	GO Term
2.11	9.76e-05	GO:0009653	anatomical structure morphogenesis
1.68	9.08e-04	GO:0048731	system development
1.61	1.58e-03	GO:0048856	anatomical structure development
1.47	3.08e-02	GO:0032502	developmental process
38.50	3.33e-02	GO:0032836	glomerular basement membrane development
1.82	4.85e-02	GO:0007399	nervous system development

Gene overrepresentation in compartment category:

Enrichment	P-value	GO Accession	GO Term
2.76	4.08e-09	GO:0044421	extracellular region part
2.76	1.11e-06	GO:0005615	extracellular space
3.70	1.99e-06	GO:0031012	extracellular matrix
1.91	8.43e-06	GO:0005576	extracellular region
3.53	1.20e-04	GO:0005578	proteinaceous extracellular matrix
1.26	6.57e-03	GO:0016020	membrane
5.87	1.20e-02	GO:0005604	basement membrane

Gene overrepresentation in function category:

Enrichment	P-value	GO Accession	GO Term
5.78	6.88e-03	GO:0005201	extracellular matrix structural constituent
11.16	1.91e-02	GO:0005520	insulin-like growth factor binding