Motif ID: NFY{A,B,C}.p2

Z-value: 4.289


Transcription factors associated with NFY{A,B,C}.p2:

Gene SymbolEntrez IDGene Name
NFYA 4800 nuclear transcription factor Y, alpha
NFYB 4801 nuclear transcription factor Y, beta
NFYC 4802 nuclear transcription factor Y, gamma

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
NFYAhg19_v1_chr6_+_41040891_41040960-0.316.7e-03Click!
NFYBhg19_v1_chr12_-_104531875_104532039-0.181.1e-01Click!
NFYChg19_v1_chr1_+_41157406_41157422-0.094.2e-01Click!


Activity profile for motif NFY{A,B,C}.p2.

activity profile for motif NFY{A,B,C}.p2


Sorted Z-values histogram for motif NFY{A,B,C}.p2

Sorted Z-values for motif NFY{A,B,C}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NFY{A,B,C}.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr19_+_55851220 40.677 NM_032701
SUV420H2
suppressor of variegation 4-20 homolog 2 (Drosophila)
chr7_+_100136784 36.129 NM_006076
AGFG2
ArfGAP with FG repeats 2
chr19_+_49468557 35.684 NM_000146
FTL
ferritin, light polypeptide
chr2_-_130956011 35.664 NM_207312
TUBA3E
tubulin, alpha 3e
chr19_+_49468656 34.429 FTL
ferritin, light polypeptide
chr19_+_49468587 31.636 FTL
ferritin, light polypeptide
chr7_+_100136845 30.046 AGFG2
ArfGAP with FG repeats 2
chr19_-_17516383 29.927 NM_004335
BST2
bone marrow stromal cell antigen 2
chr15_-_72490109 28.762 NM_001012642
GRAMD2
GRAM domain containing 2
chr22_-_22089975 27.460 NM_013313
YPEL1
yippee-like 1 (Drosophila)
chr9_-_73028278 26.362 KLF9
Kruppel-like factor 9
chr2_-_96700662 26.068 NM_207328
GPAT2
glycerol-3-phosphate acyltransferase 2, mitochondrial
chr19_+_58790306 23.659 NM_021089
ZNF8
zinc finger protein 8
chr13_-_41240607 22.303 NM_002015
FOXO1
forkhead box O1
chr19_-_55677919 22.221 NM_178837
C19orf51
chromosome 19 open reading frame 51
chr17_-_38210611 21.313 MED24
mediator complex subunit 24
chr19_+_2977480 20.897 NM_001143986
NM_024760
TLE6

transducin-like enhancer of split 6 (E(sp1) homolog, Drosophila)

chr6_-_167040506 20.428 RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr17_-_38210888 20.136 NM_001079518
NM_014815
MED24

mediator complex subunit 24

chr7_+_148982371 19.764 LOC155060
AI894139 pseudogene
chr6_-_167040700 19.398 NM_021135
RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr19_-_49140569 19.249 NM_001352
DBP
D site of albumin promoter (albumin D-box) binding protein
chr19_+_49622480 18.572 NM_003660
PPFIA3
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
chr14_-_73360792 18.298 NM_012074
DPF3
D4, zinc and double PHD fingers, family 3
chr18_+_44526786 18.209 NM_031303
KATNAL2
katanin p60 subunit A-like 2
chr5_+_150400132 18.116 GPX3
glutathione peroxidase 3 (plasma)
chr19_-_46148606 17.695 NM_001193268
EML2
echinoderm microtubule associated protein like 2
chr13_-_67804432 17.441 NM_020403
NM_203487
PCDH9

protocadherin 9

chr19_+_54641475 16.950 CNOT3
CCR4-NOT transcription complex, subunit 3
chr19_+_54641420 16.892 NM_014516
CNOT3
CCR4-NOT transcription complex, subunit 3
chr19_-_42498320 16.699 NM_152296
ATP1A3
ATPase, Na+/K+ transporting, alpha 3 polypeptide
chr4_+_156680125 16.696 NM_000857
GUCY1B3
guanylate cyclase 1, soluble, beta 3
chr1_+_6052758 16.468 KCNAB2
potassium voltage-gated channel, shaker-related subfamily, beta member 2
chr19_-_54663434 16.249 NM_024316
LENG1
leukocyte receptor cluster (LRC) member 1
chr19_+_50270068 16.239 NM_014203
NM_130787
AP2A1

adaptor-related protein complex 2, alpha 1 subunit

chr4_+_75230856 16.106 NM_001432
EREG
epiregulin
chr19_+_50270271 15.883 AP2A1
adaptor-related protein complex 2, alpha 1 subunit
chr2_-_71454200 15.544 NM_020459
PAIP2B
poly(A) binding protein interacting protein 2B
chr6_-_167040659 15.336 RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr19_-_49622278 14.635 NM_018111
C19orf73
chromosome 19 open reading frame 73
chr19_-_41256349 14.487 C19orf54
chromosome 19 open reading frame 54
chr10_+_104678001 14.457 NM_017649
NM_199076
NM_199077
CNNM2


cyclin M2


chr11_-_2018885 14.188 H19
RPS12
H19, imprinted maternally expressed transcript (non-protein coding)
ribosomal protein S12
chr17_-_8059637 14.136 PER1
period homolog 1 (Drosophila)
chr17_-_1532109 14.051 NM_152346
SLC43A2
solute carrier family 43, member 2
chr19_-_55919324 13.848 NM_014501
UBE2S
ubiquitin-conjugating enzyme E2S
chr17_-_8055684 13.820 NM_002616
PER1
period homolog 1 (Drosophila)
chr12_+_113659287 13.800 TPCN1
two pore segment channel 1
chr19_+_50270263 13.762 AP2A1
adaptor-related protein complex 2, alpha 1 subunit
chr19_+_46195898 13.715 QPCTL
glutaminyl-peptide cyclotransferase-like
chrX_+_53111482 13.714 NM_022117
TSPYL2
TSPY-like 2
chr22_+_50354139 13.572 NM_001001852
PIM3
pim-3 oncogene
chr11_-_2019007 13.521 H19
H19, imprinted maternally expressed transcript (non-protein coding)
chr11_-_2019070 13.467 H19
H19, imprinted maternally expressed transcript (non-protein coding)
chr19_-_55918980 13.404 UBE2S
ubiquitin-conjugating enzyme E2S
chr17_-_47841468 13.318 FAM117A
family with sequence similarity 117, member A
chr1_-_27339326 13.160 NM_052943
FAM46B
family with sequence similarity 46, member B
chr1_+_149824180 13.127 NM_021059
NM_001005464
HIST2H3C
HIST2H3A
histone cluster 2, H3c
histone cluster 2, H3a
chr19_-_41256371 12.966 C19orf54
chromosome 19 open reading frame 54
chr12_+_113659216 12.944 NM_001143819
NM_017901
TPCN1

two pore segment channel 1

chr11_-_2018703 12.856 H19
H19, imprinted maternally expressed transcript (non-protein coding)
chr1_-_27339448 12.789 FAM46B
family with sequence similarity 46, member B
chr14_-_74551073 12.730 ALDH6A1
aldehyde dehydrogenase 6 family, member A1
chr1_-_151798552 12.627 NM_001001523
RORC
RAR-related orphan receptor C
chr12_+_113659275 12.579 TPCN1
two pore segment channel 1
chr12_+_52416615 12.575 NM_001202233
NR4A1
nuclear receptor subfamily 4, group A, member 1
chr19_+_37808780 12.408 HKR1
HKR1, GLI-Kruppel zinc finger family member
chr2_-_175712276 12.354 NM_001206602
CHN1
chimerin (chimaerin) 1
chr19_-_46272496 12.328 NM_175875
SIX5
SIX homeobox 5
chr6_-_26199439 12.328 NM_021065
NM_003530
HIST1H2AD
HIST1H3D
histone cluster 1, H2ad
histone cluster 1, H3d
chr12_-_56727720 12.315 NM_001166279
NM_014871
PAN2

PAN2 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)

chr19_+_41103055 12.282 NM_001042544
LTBP4
latent transforming growth factor beta binding protein 4
chr1_+_6052699 12.254 KCNAB2
potassium voltage-gated channel, shaker-related subfamily, beta member 2
chr12_-_122240827 12.150


chr19_+_19174792 12.130 NM_178526
SLC25A42
solute carrier family 25, member 42
chr17_+_42634598 12.008 NM_001466
FZD2
frizzled family receptor 2
chr17_-_8198605 11.962 SLC25A35
solute carrier family 25, member 35
chr12_-_122231554 11.784 NM_019034
RHOF
ras homolog gene family, member F (in filopodia)
chr1_-_46598250 11.525 NM_003629
NM_001114172
PIK3R3

phosphoinositide-3-kinase, regulatory subunit 3 (gamma)

chr20_-_45985411 11.479 NM_012408
NM_183047
NM_183048
ZMYND8


zinc finger, MYND-type containing 8


chr1_+_70876863 11.349 NM_001190463
NM_001902
NM_153742
CTH


cystathionase (cystathionine gamma-lyase)


chr19_+_36266366 11.288 NM_001172630
NM_052948
ARHGAP33

Rho GTPase activating protein 33

chr19_-_46195442 11.205 NM_004597
NM_177542
SNRPD2

small nuclear ribonucleoprotein D2 polypeptide 16.5kDa

chr2_+_219824346 11.166 NM_003936
CDK5R2
cyclin-dependent kinase 5, regulatory subunit 2 (p39)
chr12_-_56727446 11.164 NM_001127460
PAN2
PAN2 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
chr14_+_65878579 11.125 FUT8
fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
chr19_+_46498695 10.985 CCDC61
coiled-coil domain containing 61
chr4_-_185726865 10.886 ACSL1
acyl-CoA synthetase long-chain family member 1
chr14_-_75389901 10.885 RPS6KL1
ribosomal protein S6 kinase-like 1
chr5_+_150399980 10.825 NM_002084
GPX3
glutathione peroxidase 3 (plasma)
chr9_+_131843378 10.798 NM_001135917
NM_020438
DOLPP1

dolichyl pyrophosphate phosphatase 1

chr9_+_92219926 10.685 NM_006705
GADD45G
growth arrest and DNA-damage-inducible, gamma
chr9_-_37465429 10.656 ZBTB5
zinc finger and BTB domain containing 5
chr1_+_151763174 10.602


chr17_-_1531543 10.576 SLC43A2
solute carrier family 43, member 2
chr12_+_110011616 10.565 MVK
mevalonate kinase
chr16_-_69760354 10.520 NQO1
NAD(P)H dehydrogenase, quinone 1
chr16_-_69760367 10.436 NQO1
NAD(P)H dehydrogenase, quinone 1
chr19_-_45873641 10.430 ERCC2
excision repair cross-complementing rodent repair deficiency, complementation group 2
chr19_+_38893766 10.368 NM_174905
FAM98C
family with sequence similarity 98, member C
chr10_+_99344421 10.338 HOGA1
4-hydroxy-2-oxoglutarate aldolase 1
chr18_+_55711388 10.297 NM_001144967
NM_001243960
NM_015277
NEDD4L


neural precursor cell expressed, developmentally down-regulated 4-like


chr11_+_61717355 10.253 NM_001139443
NM_004183
BEST1

bestrophin 1

chr16_-_69760444 10.227 NM_000903
NM_001025433
NM_001025434
NQO1


NAD(P)H dehydrogenase, quinone 1


chr19_-_45873839 10.194 NM_000400
NM_001130867
ERCC2

excision repair cross-complementing rodent repair deficiency, complementation group 2

chr16_+_50775960 10.154 NM_001042355
NM_015247
CYLD

cylindromatosis (turban tumor syndrome)

chr19_+_46195740 10.085 NM_001163377
NM_017659
QPCTL

glutaminyl-peptide cyclotransferase-like

chr14_-_34931413 10.049 NM_138288
SPTSSA
serine palmitoyltransferase, small subunit A
chr1_-_19229016 10.026 NM_003748
NM_170726
ALDH4A1

aldehyde dehydrogenase 4 family, member A1

chr19_+_56652529 9.995 NM_001253792
NM_018337
ZNF444

zinc finger protein 444

chr9_-_35815040 9.987 NM_032593
HINT2
histidine triad nucleotide binding protein 2
chr1_+_6052357 9.930 NM_001199861
KCNAB2
potassium voltage-gated channel, shaker-related subfamily, beta member 2
chr5_+_148737613 9.810 PCYOX1L
prenylcysteine oxidase 1 like
chr14_-_74551159 9.788 NM_005589
ALDH6A1
aldehyde dehydrogenase 6 family, member A1
chr6_-_166796363 9.782 BRP44L
brain protein 44-like
chr5_+_148737569 9.763 NM_024028
PCYOX1L
prenylcysteine oxidase 1 like
chr17_+_46048467 9.510 CDK5RAP3
CDK5 regulatory subunit associated protein 3
chr17_+_77751929 9.442 NM_005189
NM_032647
CBX2

chromobox homolog 2

chr2_+_132233579 9.429 NM_080386
TUBA3D
tubulin, alpha 3d
chr9_-_37465384 9.370 NM_014872
ZBTB5
zinc finger and BTB domain containing 5
chr18_+_55711746 9.336 NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like
chr16_+_50776012 9.315 NM_001042412
CYLD
cylindromatosis (turban tumor syndrome)
chr16_+_30108398 9.301


chr14_+_103589711 9.288 TNFAIP2
tumor necrosis factor, alpha-induced protein 2
chr7_+_99933780 9.281 PILRB
paired immunoglobin-like type 2 receptor beta
chr17_+_46048477 9.252 CDK5RAP3
CDK5 regulatory subunit associated protein 3
chr17_-_47841517 9.226 NM_030802
FAM117A
family with sequence similarity 117, member A
chrX_+_49126480 9.199 PPP1R3F
protein phosphatase 1, regulatory subunit 3F
chr12_+_112563293 9.198 NM_001143906
NM_006700
TRAFD1

TRAF-type zinc finger domain containing 1

chr22_-_41032623 9.165 MKL1
megakaryoblastic leukemia (translocation) 1
chr6_-_11232883 9.103 NEDD9
neural precursor cell expressed, developmentally down-regulated 9
chr19_-_47551881 9.085 NM_017854
TMEM160
transmembrane protein 160
chr12_+_112563359 9.020 TRAFD1
TRAF-type zinc finger domain containing 1
chr4_-_149363498 8.990 NM_000901
NM_001166104
NR3C2

nuclear receptor subfamily 3, group C, member 2

chr22_-_41032684 8.878 NM_020831
MKL1
megakaryoblastic leukemia (translocation) 1
chr1_+_227127959 8.806 ADCK3
aarF domain containing kinase 3
chr22_+_50354428 8.790 PIM3
pim-3 oncogene
chr1_+_227127993 8.770 ADCK3
aarF domain containing kinase 3
chr11_-_66725790 8.731 NM_000920
NM_001040716
PC

pyruvate carboxylase

chr22_-_37172113 8.703 NM_001177701
NM_006860
IFT27

intraflagellar transport 27 homolog (Chlamydomonas)

chr17_-_38574042 8.688 NM_001067
TOP2A
topoisomerase (DNA) II alpha 170kDa
chr6_-_80247103 8.664 NM_001122769
NM_181714
LCA5

Leber congenital amaurosis 5

chr6_+_126070813 8.655 HEY2
hairy/enhancer-of-split related with YRPW motif 2
chr16_+_4743709 8.633 NUDT16L1
nudix (nucleoside diphosphate linked moiety X)-type motif 16-like 1
chr16_-_79634610 8.605 NM_001031804
NM_005360
MAF

v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian)

chr11_-_67888857 8.586 NM_001277
NM_212469
CHKA

choline kinase alpha

chr7_+_99070515 8.573 ZNF789
zinc finger protein 789
chr15_+_41056243 8.533 NM_005258
GCHFR
GTP cyclohydrolase I feedback regulator
chr19_+_1450208 8.511 APC2
adenomatosis polyposis coli 2
chr16_+_57769667 8.496 KATNB1
katanin p80 (WD repeat containing) subunit B 1
chr6_-_11232901 8.486 NM_006403
NM_182966
NEDD9

neural precursor cell expressed, developmentally down-regulated 9

chr17_+_46048406 8.478 NM_176096
CDK5RAP3
CDK5 regulatory subunit associated protein 3
chr21_+_40823779 8.475 NM_007341
SH3BGR
SH3 domain binding glutamic acid-rich protein
chr16_+_4743693 8.463 NM_001193452
NM_032349
NUDT16L1

nudix (nucleoside diphosphate linked moiety X)-type motif 16-like 1

chr12_+_110011499 8.366 NM_000431
NM_001114185
MVK

mevalonate kinase

chr9_-_35814997 8.323 HINT2
histidine triad nucleotide binding protein 2
chrX_+_154610359 8.318 NM_001017991
NM_001017990
NM_080720
H2AFB2
H2AFB1
H2AFB3
H2A histone family, member B2
H2A histone family, member B1
H2A histone family, member B3
chr14_+_24584467 8.316 NM_181357
DCAF11
DDB1 and CUL4 associated factor 11
chr16_-_1876528 8.298 HAGH
hydroxyacylglutathione hydrolase
chr11_-_119252364 8.292 NM_001243759
NM_004205
USP2

ubiquitin specific peptidase 2

chr19_-_5340700 8.274 NM_002850
NM_130853
NM_130854
NM_130855
PTPRS



protein tyrosine phosphatase, receptor type, S



chr10_-_99446899 8.270 NM_021732
AVPI1
arginine vasopressin-induced 1
chr6_-_11232900 8.257 NEDD9
neural precursor cell expressed, developmentally down-regulated 9
chr11_-_2906960 8.238 NM_000076
NM_001122630
NM_001122631
CDKN1C


cyclin-dependent kinase inhibitor 1C (p57, Kip2)


chrX_+_49126299 8.234 NM_001184745
NM_033215
PPP1R3F

protein phosphatase 1, regulatory subunit 3F

chr19_+_38893804 8.211 FAM98C
family with sequence similarity 98, member C
chr17_+_46970128 8.203 NM_001002027
NM_005175
ATP5G1

ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)

chr19_-_14228362 8.187 NM_002730
PRKACA
protein kinase, cAMP-dependent, catalytic, alpha
chr1_+_213123853 8.175 NM_001136474
NM_001136475
NM_024749
VASH2


vasohibin 2


chr9_+_131798899 8.163 FAM73B
family with sequence similarity 73, member B
chr16_+_10479911 8.110 ATF7IP2
activating transcription factor 7 interacting protein 2
chr17_+_80416530 8.109 NM_001083608
NM_012336
NM_031968
NARF


nuclear prelamin A recognition factor


chr9_-_123476578 8.107 NM_001080497
MEGF9
multiple EGF-like-domains 9
chr16_+_57769626 8.103 NM_005886
KATNB1
katanin p80 (WD repeat containing) subunit B 1
chr17_+_80416606 8.063 NARF
nuclear prelamin A recognition factor
chr7_-_100183722 8.057 LRCH4
leucine-rich repeats and calponin homology (CH) domain containing 4
chr19_-_58951588 8.047 NM_003433
ZNF132
zinc finger protein 132
chr19_-_2702662 8.042 GNG7
guanine nucleotide binding protein (G protein), gamma 7
chr16_-_1832576 8.013 NM_080861
SPSB3
splA/ryanodine receptor domain and SOCS box containing 3
chr6_-_33285718 7.977 NM_001145338
ZBTB22
zinc finger and BTB domain containing 22
chr3_+_197687070 7.966 NM_001136049
NM_033029
LMLN

leishmanolysin-like (metallopeptidase M8 family)

chr6_-_26197477 7.951 HIST1H3D
histone cluster 1, H3d
chrX_-_154689587 7.945 NM_001017991
NM_001017990
NM_080720
H2AFB2
H2AFB1
H2AFB3
H2A histone family, member B2
H2A histone family, member B1
H2A histone family, member B3
chr3_+_193853937 7.928 HES1
hairy and enhancer of split 1, (Drosophila)
chr11_+_34642651 7.908 EHF
ets homologous factor
chr1_+_227127999 7.897 ADCK3
aarF domain containing kinase 3
chr7_+_149535508 7.893 NM_001099220
ZNF862
zinc finger protein 862
chr1_-_149399159 7.882 NM_001024599
HIST2H2BF
histone cluster 2, H2bf
chr3_+_193853930 7.879 NM_005524
HES1
hairy and enhancer of split 1, (Drosophila)
chr14_+_74551655 7.852 NM_001024674
LIN52
lin-52 homolog (C. elegans)
chr15_+_41523401 7.833 NM_007236
CHP
calcium binding protein P22
chr9_-_20622476 7.824 NM_004529
MLLT3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr11_+_34642587 7.820 NM_001206615
NM_012153
EHF

ets homologous factor

chr9_-_20622433 7.816 MLLT3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr1_-_21671905 7.742 NM_001113348
ECE1
endothelin converting enzyme 1
chr2_-_192711923 7.733 NM_004657
SDPR
serum deprivation response
chr12_-_107380837 7.604 NM_001033050
NM_025198
MTERFD3

MTERF domain containing 3

chr16_-_1832304 7.596 SPSB3
splA/ryanodine receptor domain and SOCS box containing 3
chr16_+_640091 7.582 RAB40C
RAB40C, member RAS oncogene family
chr19_+_11998609 7.547 NM_021915
ZNF69
zinc finger protein 69

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
3.01 1.29e-17 GO:0000279 M phase
1.93 1.49e-17 GO:0006996 organelle organization
2.20 4.84e-17 GO:0007049 cell cycle
2.41 1.08e-14 GO:0022403 cell cycle phase
3.23 2.12e-14 GO:0000087 M phase of mitotic cell cycle
2.24 9.29e-14 GO:0022402 cell cycle process
2.41 6.94e-13 GO:0051276 chromosome organization
3.12 1.26e-12 GO:0000280 nuclear division
3.12 1.26e-12 GO:0007067 mitosis
2.42 3.03e-12 GO:0000278 mitotic cell cycle
3.02 6.26e-12 GO:0048285 organelle fission
1.29 6.01e-11 GO:0044237 cellular metabolic process
3.94 2.04e-10 GO:0006333 chromatin assembly or disassembly
4.24 3.70e-10 GO:0071824 protein-DNA complex subunit organization
4.35 3.78e-10 GO:0065004 protein-DNA complex assembly
2.44 6.15e-10 GO:0006325 chromatin organization
4.39 6.95e-10 GO:0034728 nucleosome organization
3.96 7.27e-10 GO:0006323 DNA packaging
3.68 9.93e-10 GO:0071103 DNA conformation change
4.56 1.23e-09 GO:0006334 nucleosome assembly
1.25 1.88e-09 GO:0008152 metabolic process
1.51 3.23e-09 GO:0071842 cellular component organization at cellular level
4.32 5.80e-09 GO:0031497 chromatin assembly
2.61 6.42e-09 GO:0051301 cell division
1.51 9.41e-09 GO:0009058 biosynthetic process
7.43 1.31e-08 GO:0006695 cholesterol biosynthetic process
1.26 2.01e-08 GO:0044238 primary metabolic process
6.62 3.86e-08 GO:0016126 sterol biosynthetic process
1.46 9.14e-08 GO:0071841 cellular component organization or biogenesis at cellular level
1.49 1.31e-07 GO:0044249 cellular biosynthetic process
3.94 1.75e-07 GO:0007059 chromosome segregation
2.05 4.81e-07 GO:0051726 regulation of cell cycle
1.38 6.30e-07 GO:0016043 cellular component organization
1.12 2.11e-06 GO:0009987 cellular process
1.35 8.90e-06 GO:0071840 cellular component organization or biogenesis
1.29 9.70e-06 GO:0044260 cellular macromolecule metabolic process
1.51 2.01e-05 GO:0044281 small molecule metabolic process
2.06 3.05e-05 GO:0034621 cellular macromolecular complex subunit organization
2.20 8.84e-05 GO:0034622 cellular macromolecular complex assembly
2.17 1.05e-04 GO:0008610 lipid biosynthetic process
1.34 1.26e-04 GO:0034641 cellular nitrogen compound metabolic process
2.21 1.40e-04 GO:0010564 regulation of cell cycle process
3.42 1.47e-04 GO:0006694 steroid biosynthetic process
2.20 2.16e-04 GO:0006281 DNA repair
1.73 2.28e-04 GO:0033554 cellular response to stress
1.32 2.54e-04 GO:0006807 nitrogen compound metabolic process
2.00 3.59e-04 GO:0006066 alcohol metabolic process
1.70 5.95e-04 GO:0043933 macromolecular complex subunit organization
3.14 8.63e-04 GO:0000086 G2/M transition of mitotic cell cycle
2.40 1.20e-03 GO:0051186 cofactor metabolic process
1.74 1.60e-03 GO:0065003 macromolecular complex assembly
4.45 2.80e-03 GO:0000819 sister chromatid segregation
1.62 3.12e-03 GO:0055114 oxidation-reduction process
3.08 3.71e-03 GO:0016125 sterol metabolic process
1.36 4.52e-03 GO:0090304 nucleic acid metabolic process
3.28 6.86e-03 GO:0007088 regulation of mitosis
3.28 6.86e-03 GO:0051783 regulation of nuclear division
4.43 7.04e-03 GO:0000070 mitotic sister chromatid segregation
1.41 1.03e-02 GO:0034645 cellular macromolecule biosynthetic process
1.20 1.24e-02 GO:0043170 macromolecule metabolic process
1.41 1.28e-02 GO:0009059 macromolecule biosynthetic process
2.05 1.36e-02 GO:0051325 interphase
1.96 1.50e-02 GO:0016568 chromatin modification
3.01 1.58e-02 GO:0008203 cholesterol metabolic process
2.41 1.70e-02 GO:0006732 coenzyme metabolic process
1.30 1.72e-02 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.78 1.78e-02 GO:0006974 response to DNA damage stimulus
1.25 1.95e-02 GO:0080090 regulation of primary metabolic process
2.59 2.03e-02 GO:0006310 DNA recombination
2.10 2.21e-02 GO:0007346 regulation of mitotic cell cycle
1.70 3.77e-02 GO:0006259 DNA metabolic process
2.18 3.98e-02 GO:0071156 regulation of cell cycle arrest
1.99 4.76e-02 GO:0051329 interphase of mitotic cell cycle

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
1.36 2.83e-37 GO:0043227 membrane-bounded organelle
1.24 8.11e-37 GO:0005622 intracellular
1.36 8.75e-37 GO:0043231 intracellular membrane-bounded organelle
1.25 1.96e-35 GO:0044424 intracellular part
1.31 3.95e-35 GO:0043226 organelle
1.31 8.57e-35 GO:0043229 intracellular organelle
1.47 1.59e-26 GO:0044422 organelle part
1.47 3.47e-26 GO:0044446 intracellular organelle part
1.45 1.65e-23 GO:0005634 nucleus
1.30 2.00e-22 GO:0005737 cytoplasm
1.38 7.81e-19 GO:0044444 cytoplasmic part
2.64 4.70e-17 GO:0005694 chromosome
2.74 1.28e-15 GO:0044427 chromosomal part
2.26 5.92e-13 GO:0015630 microtubule cytoskeleton
2.24 1.59e-12 GO:0044429 mitochondrial part
3.22 4.46e-12 GO:0000785 chromatin
1.81 7.53e-12 GO:0005739 mitochondrion
1.55 2.74e-10 GO:0070013 intracellular organelle lumen
1.54 3.96e-10 GO:0031974 membrane-enclosed lumen
1.52 2.18e-09 GO:0043233 organelle lumen
1.44 2.06e-08 GO:0043228 non-membrane-bounded organelle
1.44 2.06e-08 GO:0043232 intracellular non-membrane-bounded organelle
1.50 4.88e-08 GO:0044428 nuclear part
2.16 3.56e-07 GO:0005740 mitochondrial envelope
4.66 9.59e-07 GO:0000786 nucleosome
1.88 9.94e-07 GO:0031967 organelle envelope
1.85 2.41e-06 GO:0031975 envelope
1.46 2.67e-06 GO:0005829 cytosol
2.06 1.27e-05 GO:0031966 mitochondrial membrane
3.02 1.28e-05 GO:0000793 condensed chromosome
2.41 2.08e-05 GO:0005759 mitochondrial matrix
2.66 4.48e-05 GO:0005819 spindle
1.44 1.07e-04 GO:0031981 nuclear lumen
1.29 1.14e-04 GO:0032991 macromolecular complex
2.21 1.87e-04 GO:0005874 microtubule
2.76 2.61e-04 GO:0000775 chromosome, centromeric region
2.03 8.82e-04 GO:0005815 microtubule organizing center
3.09 9.43e-04 GO:0032993 protein-DNA complex
1.45 3.55e-03 GO:0005654 nucleoplasm
11.65 3.82e-03 GO:0032389 MutLalpha complex
1.04 4.15e-03 GO:0044464 cell part
1.04 4.26e-03 GO:0005623 cell
1.26 7.83e-03 GO:0043234 protein complex
2.80 7.92e-03 GO:0005741 mitochondrial outer membrane
3.56 8.15e-03 GO:0000794 condensed nuclear chromosome
2.11 1.26e-02 GO:0005813 centrosome
2.56 1.30e-02 GO:0031968 organelle outer membrane
1.92 1.36e-02 GO:0005743 mitochondrial inner membrane
1.31 1.77e-02 GO:0031090 organelle membrane
3.18 1.78e-02 GO:0000922 spindle pole
2.48 2.19e-02 GO:0019867 outer membrane
2.22 2.54e-02 GO:0044454 nuclear chromosome part
6.99 3.05e-02 GO:0032300 mismatch repair complex
2.06 3.19e-02 GO:0000228 nuclear chromosome
2.91 3.20e-02 GO:0000779 condensed chromosome, centromeric region
1.43 4.41e-02 GO:0044430 cytoskeletal part
1.81 4.67e-02 GO:0019866 organelle inner membrane

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
1.11 1.08e-07 GO:0005488 binding
1.17 5.03e-05 GO:0005515 protein binding
1.21 1.55e-04 GO:0003824 catalytic activity
1.37 2.41e-04 GO:0003677 DNA binding
1.25 6.88e-03 GO:0003676 nucleic acid binding
1.58 1.38e-02 GO:0019899 enzyme binding
9.99 1.93e-02 GO:0016885 ligase activity, forming carbon-carbon bonds