Motif ID: NFIX.p2

Z-value: 1.205


Transcription factors associated with NFIX.p2:

Gene SymbolEntrez IDGene Name
NFIX 4784 nuclear factor I/X (CCAAT-binding transcription factor)

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
NFIXhg19_v1_chr19_+_13135368_13135427-0.161.8e-01Click!


Activity profile for motif NFIX.p2.

activity profile for motif NFIX.p2


Sorted Z-values histogram for motif NFIX.p2

Sorted Z-values for motif NFIX.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NFIX.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_+_79086087 7.632 NM_006820
IFI44L
interferon-induced protein 44-like
chr9_+_130911731 7.160 NM_005564
LCN2
lipocalin 2
chr20_+_43344005 6.309 WISP2
WNT1 inducible signaling pathway protein 2
chr2_+_103236147 6.293 NM_003048
SLC9A2
solute carrier family 9 (sodium/hydrogen exchanger), member 2
chr4_-_85419386 5.798 NM_006168
NKX6-1
NK6 homeobox 1
chr4_-_75719686 5.560 NM_001729
BTC
betacellulin
chr19_-_6720585 5.273 NM_000064
C3
complement component 3
chr19_+_30156326 5.038 NM_024310
PLEKHF1
pleckstrin homology domain containing, family F (with FYVE domain) member 1
chr17_-_80275370 4.953 NM_006137
CD7
CD7 molecule
chr11_-_61735108 4.830 NM_002032
FTH1
ferritin, heavy polypeptide 1
chr11_-_61735067 4.790 FTH1
CPSF7
ferritin, heavy polypeptide 1
cleavage and polyadenylation specific factor 7, 59kDa
chr19_-_59066477 4.083 NM_014453
CHMP2A
charged multivesicular body protein 2A
chr10_-_104211244 4.015 NM_024886
C10orf95
chromosome 10 open reading frame 95
chr16_+_2880172 3.885 NM_145252
ZG16B
zymogen granule protein 16 homolog B (rat)
chr1_+_20915440 3.867 NM_001785
CDA
cytidine deaminase
chr19_-_3028901 3.828 NM_003260
TLE2
transducin-like enhancer of split 2 (E(sp1) homolog, Drosophila)
chr19_+_47105327 3.794 CALM3
calmodulin 3 (phosphorylase kinase, delta)
chrX_+_10124984 3.553 NM_001830
CLCN4
chloride channel 4
chr11_-_61734896 3.452 FTH1
ferritin, heavy polypeptide 1
chrX_+_38660692 3.328 MID1IP1
MID1 interacting protein 1 (gastrulation specific G12 homolog (zebrafish))
chr19_+_18451365 3.302 NM_017712
PGPEP1
pyroglutamyl-peptidase I
chr17_-_3599298 3.292 P2RX5
purinergic receptor P2X, ligand-gated ion channel, 5
chr19_+_30156375 3.290


chrX_+_38660653 3.275 NM_001098790
NM_001098791
MID1IP1

MID1 interacting protein 1 (gastrulation specific G12 homolog (zebrafish))

chr2_+_201983419 3.274 CFLAR
CASP8 and FADD-like apoptosis regulator
chr19_-_59066353 3.231 NM_198426
CHMP2A
charged multivesicular body protein 2A
chr19_-_59066303 3.210 CHMP2A
charged multivesicular body protein 2A
chr5_+_150400132 3.192 GPX3
glutathione peroxidase 3 (plasma)
chr15_+_91769329 3.139 SV2B
synaptic vesicle glycoprotein 2B
chr2_+_11886739 3.094 NM_145693
LPIN1
lipin 1
chr19_+_41116069 3.025


chr4_-_25864430 3.004 NM_015187
SEL1L3
sel-1 suppressor of lin-12-like 3 (C. elegans)
chr2_+_201983268 2.995 NM_001127183
CFLAR
CASP8 and FADD-like apoptosis regulator
chr17_-_70588942 2.959 LOC100499467
uncharacterized LOC100499467
chr5_-_65017874 2.900 NM_019072
SGTB
small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta
chr5_+_34684611 2.884 NM_001145521
NM_001145525
RAI14

retinoic acid induced 14

chr6_-_109761707 2.877 PPIL6
peptidylprolyl isomerase (cyclophilin)-like 6
chr21_+_33784751 2.786 NM_058187
C21orf63
chromosome 21 open reading frame 63
chr19_+_54369610 2.768 NM_001020820
MYADM
myeloid-associated differentiation marker
chr19_+_46195898 2.745 QPCTL
glutaminyl-peptide cyclotransferase-like
chr7_+_93551015 2.743 NM_004126
GNG11
guanine nucleotide binding protein (G protein), gamma 11
chr19_-_17516383 2.709 NM_004335
BST2
bone marrow stromal cell antigen 2
chr15_-_74501309 2.678 NM_001142617
NM_001142619
NM_001142620
STRA6


stimulated by retinoic acid gene 6 homolog (mouse)


chr4_+_77227799 2.657 STBD1
starch binding domain 1
chr19_-_59066458 2.654 CHMP2A
charged multivesicular body protein 2A
chr11_+_67776016 2.650 NM_001161473
ALDH3B1
aldehyde dehydrogenase 3 family, member B1
chr7_+_65670256 2.639 NM_003596
TPST1
tyrosylprotein sulfotransferase 1
chr11_+_45825873 2.618 SLC35C1
solute carrier family 35, member C1
chr11_+_10472223 2.599 NM_000480
AMPD3
adenosine monophosphate deaminase 3
chr10_-_17271955 2.592


chr19_-_59066372 2.578 CHMP2A
charged multivesicular body protein 2A
chr3_-_194353908 2.567 TMEM44
transmembrane protein 44
chr19_+_46195740 2.566 NM_001163377
NM_017659
QPCTL

glutaminyl-peptide cyclotransferase-like

chr15_-_80215663 2.557 NM_001100880
NM_001199757
ST20

suppressor of tumorigenicity 20

chr8_-_6735438 2.527 NM_005218
DEFB1
defensin, beta 1
chr16_+_15528324 2.522 NM_033201
C16orf45
chromosome 16 open reading frame 45
chr12_-_122231554 2.516 NM_019034
RHOF
ras homolog gene family, member F (in filopodia)
chr9_-_32526164 2.509 NM_014314
DDX58
DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
chr17_-_3599359 2.470 P2RX5
purinergic receptor P2X, ligand-gated ion channel, 5
chr20_+_43343884 2.454 NM_003881
WISP2
WNT1 inducible signaling pathway protein 2
chr19_+_7599037 2.439 NM_006702
NM_001166112
PNPLA6

patatin-like phospholipase domain containing 6

chr19_+_56124958 2.435 NM_001195605
ZNF865
zinc finger protein 865
chr3_-_194354009 2.394 NM_001011655
NM_001166305
NM_001166306
NM_138399
TMEM44



transmembrane protein 44



chr13_-_102068705 2.363 NM_052867
NALCN
sodium leak channel, non-selective
chr17_-_16256708 2.358 NM_181716
CENPV
centromere protein V
chr19_-_16045669 2.351 NM_001128932
NM_021187
CYP4F11

cytochrome P450, family 4, subfamily F, polypeptide 11

chr15_+_84841241 2.344 NM_001243531
LOC100505679
uncharacterized LOC100505679
chr4_-_103266286 2.319 NM_022154
SLC39A8
solute carrier family 39 (zinc transporter), member 8
chr19_-_46195442 2.294 NM_004597
NM_177542
SNRPD2

small nuclear ribonucleoprotein D2 polypeptide 16.5kDa

chr5_+_150399980 2.286 NM_002084
GPX3
glutathione peroxidase 3 (plasma)
chr10_-_14816895 2.275 NM_031453
FAM107B
family with sequence similarity 107, member B
chr19_-_54693167 2.270 MBOAT7
membrane bound O-acyltransferase domain containing 7
chr16_-_28608367 2.210 NM_001054
SULT1A2
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
chr9_+_71736385 2.191 TJP2
tight junction protein 2 (zona occludens 2)
chr14_-_95942037 2.190 NM_152592
C14orf49
chromosome 14 open reading frame 49
chr12_+_83080901 2.171 NM_152588
TMTC2
transmembrane and tetratricopeptide repeat containing 2
chr1_+_47264669 2.170 NM_000779
NM_001099772
CYP4B1

cytochrome P450, family 4, subfamily B, polypeptide 1

chr8_+_86089641 2.163


chr10_-_735522 2.160 NM_014974
DIP2C
DIP2 disco-interacting protein 2 homolog C (Drosophila)
chr19_+_859658 2.144 NM_001928
CFD
complement factor D (adipsin)
chr12_+_75874512 2.128 NM_006851
GLIPR1
GLI pathogenesis-related 1
chr6_-_24645955 2.092 NM_001168375
NM_001168376
NM_001168374
NM_001168377
NM_014809
KIAA0319




KIAA0319




chr5_+_65017993 2.042 NM_020726
NLN
neurolysin (metallopeptidase M3 family)
chr12_+_83080621 2.038 TMTC2
transmembrane and tetratricopeptide repeat containing 2
chr22_+_50919970 2.037 NM_024866
NM_001253845
ADM2

adrenomedullin 2

chr4_+_77227178 2.020 NM_003943
STBD1
starch binding domain 1
chr5_+_34656482 2.015 RAI14
retinoic acid induced 14
chr22_-_24640850 2.009 NM_001099781
NM_001099782
NM_004121
GGT5


gamma-glutamyltransferase 5


chr1_-_6526150 1.996 NM_001039664
NM_003790
NM_148965
NM_148966
NM_148967
NM_148970
TNFRSF25





tumor necrosis factor receptor superfamily, member 25





chr4_-_103266577 1.990 NM_001135146
SLC39A8
solute carrier family 39 (zinc transporter), member 8
chr6_-_109762373 1.979 NM_001111298
NM_173672
PPIL6

peptidylprolyl isomerase (cyclophilin)-like 6

chr9_+_34179058 1.972 UBAP1
ubiquitin associated protein 1
chr10_-_88853826 1.954 GLUD1
glutamate dehydrogenase 1
chr17_-_16256824 1.942 CENPV
centromere protein V
chr1_+_44457231 1.939 NM_152499
CCDC24
coiled-coil domain containing 24
chr5_+_34656595 1.923 NM_001145520
RAI14
retinoic acid induced 14
chr10_+_17271859 1.915 VIM
vimentin
chr17_-_73266276 1.896 NM_001242500
NM_001242501
MIF4GD

MIF4G domain containing

chr4_-_103265818 1.895 SLC39A8
solute carrier family 39 (zinc transporter), member 8
chr15_-_74495093 1.893 NM_001199042
NM_022369
STRA6

stimulated by retinoic acid gene 6 homolog (mouse)

chr5_-_59783885 1.885 NM_001165899
PDE4D
phosphodiesterase 4D, cAMP-specific
chr9_+_34179036 1.878 UBAP1
ubiquitin associated protein 1
chrX_-_19140581 1.868 NM_001079858
NM_001079859
NM_001079860
NM_001184833
NM_001184834
NM_001184835
NM_001184836
NM_001184837
NM_005756
GPR64








G protein-coupled receptor 64








chr6_-_139695784 1.863 NM_006079
CITED2
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
chr11_-_65325391 1.837 LTBP3
latent transforming growth factor beta binding protein 3
chr4_-_103266396 1.837 NM_001135147
SLC39A8
solute carrier family 39 (zinc transporter), member 8
chr9_+_34179023 1.823 UBAP1
ubiquitin associated protein 1
chr5_+_52856460 1.810 NM_002495
NDUFS4
NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase)
chr9_+_34179047 1.808 UBAP1
ubiquitin associated protein 1
chr14_-_95623606 1.804 DICER1
dicer 1, ribonuclease type III
chr3_+_52570620 1.765 NM_001124767
C3orf78
chromosome 3 open reading frame 78
chr4_+_77227882 1.740 STBD1
starch binding domain 1
chr16_-_28621279 1.737 NM_001055
NM_177529
SULT1A1

sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1

chr17_+_80190107 1.732 NM_001042423
SLC16A3
solute carrier family 16, member 3 (monocarboxylic acid transporter 4)
chr10_+_17271956 1.727 VIM
vimentin
chr19_+_46498338 1.722 NM_001080402
CCDC61
coiled-coil domain containing 61
chr9_-_74383301 1.718 NM_001135820
NM_013390
TMEM2

transmembrane protein 2

chr4_-_140223611 1.705 NM_001184987
NM_001184988
NM_001184989
NM_001184990
NDUFC1



NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa



chr16_+_3014216 1.703 NM_001253725
NM_001253726
NM_024507
NM_172229
KREMEN2



kringle containing transmembrane protein 2



chr11_+_122753390 1.701 NM_024806
NM_199124
C11orf63

chromosome 11 open reading frame 63

chrX_-_151999259 1.697 NM_004344
CETN2
centrin, EF-hand protein, 2
chr5_+_34656367 1.691 NM_001145522
NM_015577
RAI14

retinoic acid induced 14

chr9_+_34179002 1.682 NM_001171201
NM_001171202
NM_001171203
NM_001171204
NM_016525
UBAP1




ubiquitin associated protein 1




chr14_-_31676826 1.677


chr1_-_156217717 1.648 NM_198406
NM_024897
PAQR6

progestin and adipoQ receptor family member VI

chr2_-_99917638 1.616 NM_174898
LYG1
lysozyme G-like 1
chr13_-_102068838 1.614 NALCN
sodium leak channel, non-selective
chr19_-_45926819 1.609 NM_202001
ERCC1
excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)
chr2_+_219187858 1.605 NM_022572
PNKD
paroxysmal nonkinesigenic dyskinesia
chr5_+_52083685 1.592 NM_181501
NM_015946
ITGA1
PELO
integrin, alpha 1
pelota homolog (Drosophila)
chr15_-_72668184 1.587 HEXA
hexosaminidase A (alpha polypeptide)
chr4_-_8442427 1.581 NM_001101667
NM_003501
ACOX3

acyl-CoA oxidase 3, pristanoyl

chr1_+_16259046 1.580


chr7_+_94539209 1.570 NM_001166161
NM_001166162
NM_001166163
PPP1R9A


protein phosphatase 1, regulatory subunit 9A


chr20_+_43343523 1.557 WISP2
WNT1 inducible signaling pathway protein 2
chr19_-_11373117 1.551 NM_020812
DOCK6
dedicator of cytokinesis 6
chr6_-_3227776 1.547 NM_178012
TUBB2B
tubulin, beta 2B class IIb
chr2_+_219187975 1.535 PNKD
paroxysmal nonkinesigenic dyskinesia
chr19_-_45926759 1.535 ERCC1
excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)
chrX_-_9733916 1.526 NM_000273
GPR143
G protein-coupled receptor 143
chr19_-_46195171 1.509 SNRPD2
small nuclear ribonucleoprotein D2 polypeptide 16.5kDa
chr13_-_99174251 1.507 NM_003576
STK24
serine/threonine kinase 24
chr1_+_2518464 1.500 FAM213B
family with sequence similarity 213, member B
chr9_-_130667571 1.494 LOC100131355
ST6GALNAC6
uncharacterized LOC100131355
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
chr16_+_67207755 1.489 NM_003946
NM_001185057
NOL3

nucleolar protein 3 (apoptosis repressor with CARD domain)

chr5_+_159656436 1.486 NM_001445
FABP6
fatty acid binding protein 6, ileal
chr2_-_85637473 1.482 CAPG
capping protein (actin filament), gelsolin-like
chr14_+_95047792 1.477 SERPINA5
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
chr1_-_156722023 1.473 NM_001126051
NM_001126050
HDGF

hepatoma-derived growth factor

chr12_-_109531244 1.472 NM_001001655
NM_001145374
NM_001145375
NM_001205179
NM_001205180
ALKBH2




alkB, alkylation repair homolog 2 (E. coli)




chr9_+_112810877 1.457 NM_001004065
NM_001198656
AKAP2

A kinase (PRKA) anchor protein 2

chr11_+_560868 1.447 NM_001143993
RASSF7
Ras association (RalGDS/AF-6) domain family (N-terminal) member 7
chr20_-_48530275 1.446 NM_001135773
SPATA2
spermatogenesis associated 2
chr12_+_133264152 1.435 NM_018663
PXMP2
peroxisomal membrane protein 2, 22kDa
chr6_+_155538096 1.428 NM_001010927
TIAM2
T-cell lymphoma invasion and metastasis 2
chr8_-_142238672 1.426 NM_001080431
SLC45A4
solute carrier family 45, member 4
chr7_+_108210308 1.426 DNAJB9
DnaJ (Hsp40) homolog, subfamily B, member 9
chr2_-_56151273 1.423 NM_001039348
NM_001039349
EFEMP1

EGF containing fibulin-like extracellular matrix protein 1

chr7_-_91763828 1.417 NM_000786
CYP51A1
cytochrome P450, family 51, subfamily A, polypeptide 1
chr19_-_59023323 1.413 NM_012254
SLC27A5
solute carrier family 27 (fatty acid transporter), member 5
chr9_-_25678855 1.408 NM_001004125
TUSC1
tumor suppressor candidate 1
chr2_-_85637486 1.406 NM_001747
CAPG
capping protein (actin filament), gelsolin-like
chr7_-_77045706 1.399 NM_017439
PION
pigeon homolog (Drosophila)
chr9_+_112542496 1.394 NM_053016
NM_007203
NM_147150
PALM2
PALM2-AKAP2

paralemmin 2
PALM2-AKAP2 readthrough

chr5_-_68665316 1.393 NM_003187
NM_016283
TAF9

TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa

chr21_-_43373938 1.392 NM_015500
C2CD2
C2 calcium-dependent domain containing 2
chr12_-_48152180 1.386 NM_001098532
NM_006105
RAPGEF3

Rap guanine nucleotide exchange factor (GEF) 3

chr6_-_139695739 1.384 CITED2
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
chr21_+_43933983 1.382 SLC37A1
solute carrier family 37 (glycerol-3-phosphate transporter), member 1
chr3_+_196729776 1.382 MFI2-AS1
MFI2 antisense RNA 1 (non-protein coding)
chr16_-_2031359 1.380 NM_144603
NOXO1
NADPH oxidase organizer 1
chr19_-_54693414 1.376 MBOAT7
membrane bound O-acyltransferase domain containing 7
chr9_+_112810949 1.375 AKAP2
A kinase (PRKA) anchor protein 2
chrX_-_68385249 1.374 NM_001032396
NM_022368
NM_145119
PJA1


praja ring finger 1


chr2_+_205410716 1.373 PARD3B
par-3 partitioning defective 3 homolog B (C. elegans)
chr5_+_304290 1.372 NM_001242412
NM_020731
AHRR

aryl-hydrocarbon receptor repressor

chr9_-_94124149 1.361 AUH
AU RNA binding protein/enoyl-CoA hydratase
chr5_-_176836488 1.360 F12
coagulation factor XII (Hageman factor)
chr15_-_72668301 1.353 NM_000520
HEXA
hexosaminidase A (alpha polypeptide)
chr1_+_6086072 1.353 NM_003636
NM_172130
KCNAB2

potassium voltage-gated channel, shaker-related subfamily, beta member 2

chr8_+_86089618 1.349 NM_001083588
NM_001951
E2F5

E2F transcription factor 5, p130-binding

chr10_-_100174891 1.349 NM_032709
PYROXD2
pyridine nucleotide-disulphide oxidoreductase domain 2
chr7_-_91763677 1.342 CYP51A1
cytochrome P450, family 51, subfamily A, polypeptide 1
chr12_-_58026429 1.341 B4GALNT1
beta-1,4-N-acetyl-galactosaminyl transferase 1
chr19_+_3708358 1.339 TJP3
tight junction protein 3 (zona occludens 3)
chr5_+_178986692 1.338 NM_001040451
NM_001040452
RUFY1

RUN and FYVE domain containing 1

chr5_+_154092461 1.334 NM_015315
LARP1
La ribonucleoprotein domain family, member 1
chr6_+_109761887 1.334 NM_003080
SMPD2
sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
chr5_-_179229874 1.333 NM_054013
MGAT4B
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme B
chr12_-_133263988 1.328 POLE
polymerase (DNA directed), epsilon
chr4_+_8442496 1.310 NM_152544
METTL19
methyltransferase like 19
chr9_-_130617009 1.298 NM_000118
NM_001114753
ENG

endoglin

chr19_-_55895602 1.291 NM_001190764
TMEM238
transmembrane protein 238
chr9_-_25678230 1.290 TUSC1
tumor suppressor candidate 1
chr12_+_102091399 1.287 NM_020244
CHPT1
choline phosphotransferase 1
chr9_-_132515290 1.281 NM_004878
PTGES
prostaglandin E synthase
chr15_-_80216004 1.271 ST20
suppressor of tumorigenicity 20
chr10_-_91011516 1.265 LIPA
lipase A, lysosomal acid, cholesterol esterase
chr15_+_63336274 1.263 TPM1
tropomyosin 1 (alpha)
chr19_+_1067293 1.256 HMHA1
histocompatibility (minor) HA-1

Gene Ontology Analysis

Nothing significant found in process category.

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
2.45 1.15e-03 GO:0000267 cell fraction
2.55 6.05e-03 GO:0005626 insoluble fraction
2.52 1.08e-02 GO:0005624 membrane fraction

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
1.46 1.08e-02 GO:0003824 catalytic activity