Motif ID: NFATC1..3.p2

Z-value: 1.664


Transcription factors associated with NFATC1..3.p2:

Gene SymbolEntrez IDGene Name
NFATC1 4772 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
NFATC2 4773 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
NFATC3 4775 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
NFATC2hg19_v1_chr20_-_50179167_501791670.631.9e-09Click!
NFATC1hg19_v1_chr18_+_77253324_772534360.472.3e-05Click!
NFATC3hg19_v1_chr16_+_68119332_681193440.094.5e-01Click!


Activity profile for motif NFATC1..3.p2.

activity profile for motif NFATC1..3.p2


Sorted Z-values histogram for motif NFATC1..3.p2

Sorted Z-values for motif NFATC1..3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NFATC1..3.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr15_+_25101697 42.165 NM_022805
SNRPN
small nuclear ribonucleoprotein polypeptide N
chr12_+_41086189 17.221 NM_001843
NM_175038
CNTN1

contactin 1

chr4_+_41258941 17.150 UCHL1
ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
chr2_-_127963342 16.824 NM_001001665
CYP27C1
cytochrome P450, family 27, subfamily C, polypeptide 1
chr20_+_44746889 15.561 NM_001250
NM_152854
CD40

CD40 molecule, TNF receptor superfamily member 5

chr2_+_113735595 14.017 NM_019618
IL36G
interleukin 36, gamma
chr15_+_25230199 13.166 PAR5
Prader-Willi/Angelman syndrome-5
chr2_-_238322770 12.130 COL6A3
collagen, type VI, alpha 3
chr2_-_238322840 11.975 NM_004369
NM_057164
NM_057165
NM_057166
NM_057167
COL6A3




collagen, type VI, alpha 3




chr4_+_41258909 11.679 UCHL1
ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
chr9_+_131870105 11.561


chr11_-_105010460 11.173 NM_021571
CARD18
caspase recruitment domain family, member 18
chr16_+_82660390 11.132 NM_001220488
NM_001220489
NM_001220490
NM_001220491
NM_001220492
NM_001257
CDH13





cadherin 13, H-cadherin (heart)





chr16_+_82660641 10.964 CDH13
cadherin 13, H-cadherin (heart)
chr12_-_28124915 10.827 NM_002820
NM_198965
PTHLH

parathyroid hormone-like hormone

chr5_+_140602914 10.813 NM_018934
PCDHB14
protocadherin beta 14
chrX_-_70331297 10.807 NM_000206
IL2RG
interleukin 2 receptor, gamma
chr6_+_106546736 10.758 NM_182907
PRDM1
PR domain containing 1, with ZNF domain
chr5_+_140254930 10.628 NM_018903
NM_031864
PCDHA12

protocadherin alpha 12

chr16_+_82660573 10.020 CDH13
cadherin 13, H-cadherin (heart)
chr15_+_25068793 9.916 NM_022806
NM_022807
NM_022808
SNRPN


small nuclear ribonucleoprotein polypeptide N


chr8_-_82395401 9.521 NM_001442
FABP4
fatty acid binding protein 4, adipocyte
chr2_-_238322806 9.095 COL6A3
collagen, type VI, alpha 3
chr8_-_22550057 9.051 NM_001199881
EGR3
early growth response 3
chr4_+_41258895 8.804 NM_004181
UCHL1
ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
chr5_+_140474198 8.681 NM_018936
PCDHB2
protocadherin beta 2
chr18_+_28898051 8.620 NM_001942
DSG1
desmoglein 1
chr1_+_161676761 8.452 NM_001184866
NM_001184867
NM_001184870
NM_001184871
NM_001184872
NM_001184873
NM_032738
FCRLA






Fc receptor-like A






chr7_+_1126442 8.370 NM_001039966
NM_001505
GPER

G protein-coupled estrogen receptor 1

chr5_+_59784004 8.246 PART1
prostate androgen-regulated transcript 1 (non-protein coding)
chr13_-_49110117 8.009 RCBTB2
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
chr2_-_238322814 7.923 COL6A3
collagen, type VI, alpha 3
chrX_+_102632108 7.852 NM_014380
NGFRAP1
nerve growth factor receptor (TNFRSF16) associated protein 1
chr1_-_120311466 7.683 NM_001166107
NM_005518
HMGCS2

3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial)

chr1_+_24645914 7.682 NM_001195010
GRHL3
grainyhead-like 3 (Drosophila)
chr9_-_215892 7.458 NM_152569
C9orf66
chromosome 9 open reading frame 66
chr2_-_238322815 7.356 COL6A3
collagen, type VI, alpha 3
chrX_+_152760346 7.302 NM_001711
BGN
biglycan
chr5_+_140593508 7.179 NM_018933
PCDHB13
protocadherin beta 13
chr7_+_1127722 7.156 NM_001098201
GPER
G protein-coupled estrogen receptor 1
chr1_+_100111430 7.055 NM_017734
PALMD
palmdelphin
chr10_-_105212149 7.053 NM_015916
CALHM2
calcium homeostasis modulator 2
chr1_+_24645811 7.012 NM_198173
NM_198174
GRHL3

grainyhead-like 3 (Drosophila)

chr5_+_140566655 6.943 NM_019119
PCDHB9
protocadherin beta 9
chr14_-_75422466 6.711 NM_001207012
NM_002632
PGF

placental growth factor

chr17_+_60704747 6.562 NM_006039
MRC2
mannose receptor, C type 2
chr3_-_74570262 6.399 NM_020872
CNTN3
contactin 3 (plasmacytoma associated)
chrX_-_38079980 6.396 NM_001170750
NM_001170751
NM_001170752
NM_006307
SRPX



sushi-repeat containing protein, X-linked



chr5_+_140247767 6.245 NM_018902
NM_031861
PCDHA11

protocadherin alpha 11

chr17_-_39216343 6.222 NM_001165252
LOC730755
keratin associated protein 2-4-like
chr3_+_49208979 6.180 NM_173546
KLHDC8B
kelch domain containing 8B
chr20_+_58713521 6.146 LOC284757
uncharacterized LOC284757
chr15_+_50474357 6.124 NM_001159629
NM_003645
SLC27A2

solute carrier family 27 (fatty acid transporter), member 2

chr15_+_25227140 5.957 SNRPN
small nuclear ribonucleoprotein polypeptide N
chr2_-_96811138 5.878 NM_004418
DUSP2
dual specificity phosphatase 2
chr1_+_40974430 5.822 NM_022774
DEM1
defects in morphology 1 homolog (S. cerevisiae)
chr10_-_105212022 5.705 CALHM2
calcium homeostasis modulator 2
chr19_+_36347809 5.687 NM_032123
NM_199179
NM_199180
KIRREL2


kin of IRRE like 2 (Drosophila)


chr5_+_140625146 5.645 NM_018935
PCDHB15
protocadherin beta 15
chrX_+_152760452 5.551 BGN
biglycan
chr11_+_101918168 5.537 NM_001195005
NM_032930
C11orf70

chromosome 11 open reading frame 70

chr1_+_111889194 5.444 NM_181643
C1orf88
chromosome 1 open reading frame 88
chr6_+_136172802 5.414 NM_018945
PDE7B
phosphodiesterase 7B
chr1_-_221910801 5.405 NM_144728
DUSP10
dual specificity phosphatase 10
chrX_+_102631267 5.338 NM_206915
NM_206917
NGFRAP1

nerve growth factor receptor (TNFRSF16) associated protein 1

chr15_+_32933869 5.234 NM_001144757
NM_003020
SCG5

secretogranin V (7B2 protein)

chr5_+_55147206 5.191 NM_001242637
NM_001242638
NM_139017
IL31RA


interleukin 31 receptor A


chr18_+_61420276 5.180 NM_001040147
SERPINB7
serpin peptidase inhibitor, clade B (ovalbumin), member 7
chr8_+_75736771 5.131 NM_015886
PI15
peptidase inhibitor 15
chr3_-_108248168 5.112 NM_014981
MYH15
myosin, heavy chain 15
chr1_-_183387404 5.102


chr11_+_129245834 5.101 NM_003658
BARX2
BARX homeobox 2
chr5_-_111093792 5.096 NM_001142477
NM_001142476
C5orf13

chromosome 5 open reading frame 13

chr3_-_99594915 5.054 NM_014890
FILIP1L
filamin A interacting protein 1-like
chr6_+_106534210 5.053 PRDM1
PR domain containing 1, with ZNF domain
chr5_+_140174443 4.953 NM_018905
NM_031495
PCDHA2

protocadherin alpha 2

chr11_+_123986103 4.904 NM_001130142
NM_014622
NM_198315
VWA5A


von Willebrand factor A domain containing 5A


chr18_-_56296188 4.892 NM_052947
ALPK2
alpha-kinase 2
chr12_+_9142136 4.874 NM_005810
KLRG1
killer cell lectin-like receptor subfamily G, member 1
chrX_-_154563735 4.836 NM_001289
CLIC2
chloride intracellular channel 2
chr1_-_109399705 4.834 NM_152763
AKNAD1
AKNA domain containing 1
chr19_-_9649257 4.798 NM_024106
ZNF426
zinc finger protein 426
chr15_-_45480160 4.792 SHF
Src homology 2 domain containing F
chrX_+_2670092 4.776 NM_001141919
NM_001141920
NM_175569
XGPY2
XG


Xg pseudogene, Y-linked 2
Xg blood group


chrX_-_51239295 4.752 NUDT11
nudix (nucleoside diphosphate linked moiety X)-type motif 11
chr10_-_98031154 4.661 NM_001114094
NM_013314
BLNK

B-cell linker

chr3_-_193272587 4.610 NM_032279
ATP13A4
ATPase type 13A4
chr5_+_140207562 4.607 NM_018909
NM_031848
NM_031849
PCDHA6


protocadherin alpha 6


chr16_+_50731049 4.607 NM_022162
NOD2
nucleotide-binding oligomerization domain containing 2
chr7_+_23286401 4.589 GPNMB
glycoprotein (transmembrane) nmb
chr1_-_32169555 4.581 COL16A1
collagen, type XVI, alpha 1
chrX_+_105937067 4.580 NM_024539
RNF128
ring finger protein 128
chr1_-_32169619 4.553 NM_001856
COL16A1
collagen, type XVI, alpha 1
chr6_+_13924676 4.547 NM_001165034
RNF182
ring finger protein 182
chr8_-_95274540 4.432 NM_005261
NM_181702
GEM

GTP binding protein overexpressed in skeletal muscle

chr12_-_10282680 4.407 NM_022570
NM_197947
NM_197948
NM_197949
NM_197950
NM_197954
CLEC7A





C-type lectin domain family 7, member A





chr4_+_74606222 4.407 NM_000584
IL8
interleukin 8
chr1_+_207039153 4.402 NM_018724
IL20
interleukin 20
chr5_+_140809957 4.395 PCDHGA12
protocadherin gamma subfamily A, 12
chr4_-_100242487 4.395 NM_000668
ADH1A
ADH1B
alcohol dehydrogenase 1A (class I), alpha polypeptide
alcohol dehydrogenase 1B (class I), beta polypeptide
chr19_+_37342552 4.383 NM_001242475
NM_001242476
ZNF345

zinc finger protein 345

chr19_-_7553867 4.370 NM_080662
PEX11G
peroxisomal biogenesis factor 11 gamma
chr3_+_186739643 4.352 NM_003032
ST6GAL1
ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
chr9_-_36276930 4.243 NM_001128227
NM_001190388
GNE

glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase

chr11_-_85437457 4.241 NM_206927
NM_206928
SYTL2

synaptotagmin-like 2

chr5_+_140261792 4.236 NM_018904
NM_031865
PCDHA13

protocadherin alpha 13

chr10_-_64578926 4.223 NM_001136178
EGR2
early growth response 2
chr4_-_186697065 4.210 NM_001145673
SORBS2
sorbin and SH3 domain containing 2
chr20_-_1165116 4.183 NM_018354
TMEM74B
transmembrane protein 74B
chr1_+_164528586 4.148 NM_001204961
NM_001204963
NM_002585
PBX1


pre-B-cell leukemia homeobox 1


chr5_-_124080773 4.111 NM_020747
ZNF608
zinc finger protein 608
chr6_-_110736748 4.108 NM_003649
NM_004032
DDO

D-aspartate oxidase

chr11_+_22696381 4.106 GAS2
growth arrest-specific 2
chr7_+_80267782 4.099 NM_000072
NM_001001548
CD36

CD36 molecule (thrombospondin receptor)

chr3_+_113251217 4.095 NM_017699
SIDT1
SID1 transmembrane family, member 1
chr3_+_361365 4.093 NM_001253388
CHL1
cell adhesion molecule with homology to L1CAM (close homolog of L1)
chr19_+_42259397 4.064 NM_002483
CEACAM6
carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
chr1_+_247579457 4.045 NM_001079821
NM_001127461
NLRP3

NLR family, pyrin domain containing 3

chr5_-_146460991 4.037 NM_181677
NM_181678
PPP2R2B

protein phosphatase 2, regulatory subunit B, beta

chr9_+_22447353 3.976 DMRTA1
DMRT-like family A1
chr2_+_170366211 3.964 NM_006063
KBTBD10
kelch repeat and BTB (POZ) domain containing 10
chr4_-_100140330 3.928 NM_000672
NM_001102470
ADH6

alcohol dehydrogenase 6 (class V)

chr5_+_55149149 3.912 NM_001242636
NM_001242639
IL31RA

interleukin 31 receptor A

chr5_+_147648374 3.895 NM_001040129
SPINK13
serine peptidase inhibitor, Kazal type 13 (putative)
chr3_-_161089747 3.890 NM_001040100
SPTSSB
serine palmitoyltransferase, small subunit B
chr16_+_84853585 3.882 NM_031476
CRISPLD2
cysteine-rich secretory protein LCCL domain containing 2
chr1_-_221915393 3.850 DUSP10
dual specificity phosphatase 10
chr11_-_102714240 3.846 NM_002422
MMP3
matrix metallopeptidase 3 (stromelysin 1, progelatinase)
chr7_+_23286390 3.813 GPNMB
glycoprotein (transmembrane) nmb
chr5_+_140165875 3.812 NM_018900
NM_031410
NM_031411
PCDHA1


protocadherin alpha 1


chr5_-_115910406 3.810 NM_020796
SEMA6A
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr6_-_159466019 3.793 NM_054114
NM_138810
NM_152133
TAGAP


T-cell activation RhoGTPase activating protein


chr5_+_140186658 3.789 NM_018907
NM_031500
PCDHA4

protocadherin alpha 4

chr4_+_166794409 3.779 NM_001204760
NM_012464
TLL1

tolloid-like 1

chr7_+_23286384 3.777 GPNMB
glycoprotein (transmembrane) nmb
chr9_-_123688352 3.758 TRAF1
TNF receptor-associated factor 1
chr20_+_51801821 3.750 NM_001193421
TSHZ2
teashirt zinc finger homeobox 2
chr6_-_2635297 3.743 NM_152554
C6orf195
chromosome 6 open reading frame 195
chrX_-_84634664 3.734 POF1B
premature ovarian failure, 1B
chr20_+_123230 3.730 NM_030931
DEFB126
defensin, beta 126
chr12_-_10605928 3.705 NM_002259
NM_007328
KLRC1

killer cell lectin-like receptor subfamily C, member 1

chr2_+_113885137 3.694 NM_173842
IL1RN
interleukin 1 receptor antagonist
chr12_-_54694717 3.692 NM_001136023
NFE2
nuclear factor (erythroid-derived 2), 45kDa
chr5_-_150284503 3.667 NM_001172831
NM_001172832
NM_052860
ZNF300


zinc finger protein 300


chr3_-_121740968 3.643 NM_001199799
NM_001199800
NM_175924
ILDR1


immunoglobulin-like domain containing receptor 1


chr19_-_37341168 3.612 NM_001242801
ZNF790
zinc finger protein 790
chr7_+_23286386 3.608 GPNMB
glycoprotein (transmembrane) nmb
chrX_-_84634742 3.608 NM_024921
POF1B
premature ovarian failure, 1B
chr19_-_51472003 3.608 NM_001012964
NM_001012965
KLK6

kallikrein-related peptidase 6

chr2_+_69201704 3.596 NM_019617
GKN1
gastrokine 1
chr4_-_186577858 3.590 SORBS2
sorbin and SH3 domain containing 2
chr1_-_150738232 3.563 CTSS
cathepsin S
chr21_-_27945267 3.554 NM_052954
CYYR1
cysteine/tyrosine-rich 1
chr11_+_27015833 3.551 FIBIN
fin bud initiation factor homolog (zebrafish)
chrX_-_69269781 3.538 NM_001002254
AWAT2
acyl-CoA wax alcohol acyltransferase 2
chr10_-_52008312 3.525 NM_001143974
NM_019893
ASAH2

N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2

chr2_+_113885145 3.522 IL1RN
interleukin 1 receptor antagonist
chr1_+_152769226 3.521 NM_178352
LCE1D
late cornified envelope 1D
chr12_+_100750856 3.507 NM_001145288
NM_139319
SLC17A8

solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 8

chr17_-_39675078 3.504 NM_002275
KRT15
keratin 15
chr3_-_172241060 3.490 NM_001190943
NM_001190942
NM_003810
TNFSF10


tumor necrosis factor (ligand) superfamily, member 10


chrX_+_107288199 3.487 NM_001170553
NM_182607
VSIG1

V-set and immunoglobulin domain containing 1

chr12_+_9980076 3.485 NM_016523
KLRF1
killer cell lectin-like receptor subfamily F, member 1
chr1_-_221915426 3.453 DUSP10
dual specificity phosphatase 10
chr6_+_39760772 3.450 NM_015345
DAAM2
dishevelled associated activator of morphogenesis 2
chr2_+_159651828 3.447 NM_001017920
DAPL1
death associated protein-like 1
chr1_-_221915458 3.432 NM_007207
NM_144729
DUSP10

dual specificity phosphatase 10

chrX_+_102631408 3.414 NGFRAP1
nerve growth factor receptor (TNFRSF16) associated protein 1
chr2_-_219858120 3.374 NM_005209
NM_057093
NM_057094
CRYBA2


crystallin, beta A2


chr5_+_140557370 3.344 NM_019120
PCDHB8
protocadherin beta 8
chr5_+_140514787 3.340 NM_015669
PCDHB5
protocadherin beta 5
chr5_+_145317297 3.309 SH3RF2
SH3 domain containing ring finger 2
chr11_+_18194383 3.309 NM_054032
MRGPRX4
MAS-related GPR, member X4
chr10_-_62703822 3.284 NM_001242359
NM_014836
RHOBTB1

Rho-related BTB domain containing 1

chr12_-_11244828 3.242 NM_176884
TAS2R43
TAS2R31
taste receptor, type 2, member 43
taste receptor, type 2, member 31
chr1_+_164818083 3.239 PBX1
pre-B-cell leukemia homeobox 1
chr3_-_39195101 3.236 NM_033027
CSRNP1
cysteine-serine-rich nuclear protein 1
chr14_-_106573348 3.226 IGHV4-31
IGHA1
IGHA2
IGHG1
IGHG3
IGHM
immunoglobulin heavy variable 4-31
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant alpha 2 (A2m marker)
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 3 (G3m marker)
immunoglobulin heavy constant mu
chr2_-_165811995 3.196 NM_001199148
NM_173512
SLC38A11

solute carrier family 38, member 11

chr1_-_183274008 3.185 NM_170706
NMNAT2
nicotinamide nucleotide adenylyltransferase 2
chr11_-_68780667 3.164 NM_001098515
NM_145015
MRGPRF

MAS-related GPR, member F

chrX_-_84634396 3.162 POF1B
premature ovarian failure, 1B
chr5_-_141993691 3.135 NM_033137
FGF1
fibroblast growth factor 1 (acidic)
chr1_-_183387501 3.129 NM_015039
NMNAT2
nicotinamide nucleotide adenylyltransferase 2
chr1_+_150266261 3.124 NM_018997
NM_031901
MRPS21

mitochondrial ribosomal protein S21

chr7_+_28452143 3.122 NM_182898
CREB5
cAMP responsive element binding protein 5
chr5_+_140480056 3.093 NM_018937
PCDHB3
protocadherin beta 3
chrX_-_114252132 3.088 NM_000640
IL13RA2
interleukin 13 receptor, alpha 2
chr11_+_15133969 3.078 NM_001031853
INSC
inscuteable homolog (Drosophila)
chr5_-_64777703 3.075 NM_197941
ADAMTS6
ADAM metallopeptidase with thrombospondin type 1 motif, 6
chr1_+_248524882 3.068 NM_001004696
OR2T4
olfactory receptor, family 2, subfamily T, member 4
chr1_-_116383323 3.061 NM_001111061
NHLH2
nescient helix loop helix 2
chr8_-_95274520 3.051 GEM
GTP binding protein overexpressed in skeletal muscle
chr3_-_123411185 3.043 MYLK
myosin light chain kinase
chr1_+_161228516 3.029 NM_001102566
PCP4L1
Purkinje cell protein 4 like 1
chr10_+_63422718 3.012 NM_173554
C10orf107
chromosome 10 open reading frame 107
chr7_-_112727832 3.006 NM_001146265
NM_018970
GPR85

G protein-coupled receptor 85

chr5_+_68800003 3.006 NM_001205255
OCLN
occludin
chr18_-_28681885 3.003 NM_004949
NM_024422
DSC2

desmocollin 2

chr1_-_160549226 2.990 CD84
CD84 molecule

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
3.12 5.64e-20 GO:0007155 cell adhesion
3.12 5.64e-20 GO:0022610 biological adhesion
6.07 5.27e-15 GO:0007156 homophilic cell adhesion
3.91 7.72e-13 GO:0016337 cell-cell adhesion
1.39 8.50e-08 GO:0032501 multicellular organismal process
1.32 2.46e-06 GO:0050896 response to stimulus
2.01 2.66e-05 GO:0009611 response to wounding
1.84 3.05e-05 GO:0002376 immune system process
1.42 3.52e-05 GO:0023052 signaling
2.10 4.36e-05 GO:0006955 immune response
9.46 6.04e-05 GO:0016339 calcium-dependent cell-cell adhesion
2.31 1.33e-04 GO:0008284 positive regulation of cell proliferation
2.73 5.48e-04 GO:0006954 inflammatory response
3.47 7.16e-04 GO:0043062 extracellular structure organization
4.27 1.65e-03 GO:0050795 regulation of behavior
2.20 1.91e-03 GO:0001775 cell activation
9.08 2.23e-03 GO:0009595 detection of biotic stimulus
1.43 2.57e-03 GO:0048731 system development
1.56 3.04e-03 GO:0007166 cell surface receptor linked signaling pathway
3.65 3.89e-03 GO:0051606 detection of stimulus
5.24 4.16e-03 GO:0050808 synapse organization
2.20 5.41e-03 GO:0050776 regulation of immune response
1.37 6.42e-03 GO:0007165 signal transduction
1.91 1.11e-02 GO:0002682 regulation of immune system process
6.39 1.39e-02 GO:0007416 synapse assembly
1.36 1.91e-02 GO:0048856 anatomical structure development
1.81 2.08e-02 GO:0048584 positive regulation of response to stimulus
4.80 2.71e-02 GO:0048520 positive regulation of behavior
1.50 4.88e-02 GO:0003008 system process

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
2.17 1.40e-22 GO:0005576 extracellular region
1.68 1.35e-19 GO:0005886 plasma membrane
1.66 5.98e-19 GO:0071944 cell periphery
2.46 1.24e-15 GO:0044421 extracellular region part
1.43 6.57e-12 GO:0031224 intrinsic to membrane
2.12 1.55e-11 GO:0005887 integral to plasma membrane
2.10 2.20e-11 GO:0031226 intrinsic to plasma membrane
2.44 3.05e-11 GO:0005615 extracellular space
1.77 5.29e-11 GO:0044459 plasma membrane part
1.42 7.87e-11 GO:0016021 integral to membrane
3.04 5.79e-08 GO:0005578 proteinaceous extracellular matrix
1.31 1.11e-07 GO:0044425 membrane part
2.70 8.59e-07 GO:0031012 extracellular matrix
1.25 9.25e-07 GO:0016020 membrane
3.01 3.52e-02 GO:0044420 extracellular matrix part

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
1.77 9.09e-08 GO:0004872 receptor activity
1.55 6.71e-05 GO:0004871 signal transducer activity
1.55 6.71e-05 GO:0060089 molecular transducer activity
1.71 2.11e-04 GO:0004888 transmembrane receptor activity
6.24 3.59e-04 GO:0003823 antigen binding
1.76 6.55e-04 GO:0005102 receptor binding
1.95 9.58e-04 GO:0005509 calcium ion binding
7.22 1.32e-02 GO:0019956 chemokine binding
2.05 1.77e-02 GO:0015267 channel activity
2.04 1.87e-02 GO:0022803 passive transmembrane transporter activity
3.69 1.94e-02 GO:0005201 extracellular matrix structural constituent
2.05 2.15e-02 GO:0022838 substrate-specific channel activity
2.05 3.52e-02 GO:0030246 carbohydrate binding
2.03 3.57e-02 GO:0005216 ion channel activity