Motif ID: MYOD1.p2

Z-value: 1.463


Transcription factors associated with MYOD1.p2:

Gene SymbolEntrez IDGene Name
MYOD1 4654 myogenic differentiation 1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
MYOD1hg19_v1_chr11_+_17741109_177413290.539.2e-07Click!


Activity profile for motif MYOD1.p2.

activity profile for motif MYOD1.p2


Sorted Z-values histogram for motif MYOD1.p2

Sorted Z-values for motif MYOD1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MYOD1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_+_1860232 8.969 NM_003282
TNNI2
troponin I type 2 (skeletal, fast)
chrX_+_140084755 6.403 NM_145664
NM_139019
NM_032461
SPANXB2
SPANXF1
SPANXB1
SPANX family, member B2
SPANX family, member F1
SPANX family, member B1
chrX_+_140096760 6.038 NM_145664
NM_139019
NM_032461
SPANXB2
SPANXF1
SPANXB1
SPANX family, member B2
SPANX family, member F1
SPANX family, member B1
chrX_-_130964633 5.964 LOC286467
family with sequence similarity 195, member A pseudogene
chr12_+_52416615 5.948 NM_001202233
NR4A1
nuclear receptor subfamily 4, group A, member 1
chr5_+_159343739 5.855 NM_000679
ADRA1B
adrenergic, alpha-1B-, receptor
chr11_+_69061599 5.662 NM_138768
MYEOV
myeloma overexpressed (in a subset of t(11;14) positive multiple myelomas)
chr1_-_27339326 5.409 NM_052943
FAM46B
family with sequence similarity 46, member B
chr9_+_37650996 5.404 NM_014907
FRMPD1
FERM and PDZ domain containing 1
chr15_-_74501309 5.123 NM_001142617
NM_001142619
NM_001142620
STRA6


stimulated by retinoic acid gene 6 homolog (mouse)


chr17_-_39203423 5.108 NM_001123387
KRTAP2-1
keratin associated protein 2-1
chr19_+_54926604 5.091 NM_001005367
NM_001201461
NM_020659
TTYH1


tweety homolog 1 (Drosophila)


chr1_-_27339448 5.031 FAM46B
family with sequence similarity 46, member B
chr1_-_92951593 4.887 NM_001127216
GFI1
growth factor independent 1 transcription repressor
chr2_-_224467049 4.872 SCG2
secretogranin II
chr1_-_40782826 4.784 COL9A2
collagen, type IX, alpha 2
chr15_-_76352068 4.714 NRG4
neuregulin 4
chr1_-_40782924 4.694 NM_001852
COL9A2
collagen, type IX, alpha 2
chr17_-_39211462 4.640 NM_033032
KRTAP2-2
keratin associated protein 2-2
chr17_-_46035109 4.441 NM_024320
PRR15L
proline rich 15-like
chr13_+_35516390 4.441 NM_015678
NBEA
neurobeachin
chr2_-_224467095 4.426 SCG2
secretogranin II
chr2_+_209271555 4.361 NM_005048
PTH2R
parathyroid hormone 2 receptor
chr5_-_132948222 4.308 NM_015082
FSTL4
follistatin-like 4
chr10_+_124030820 4.258 NM_144587
BTBD16
BTB (POZ) domain containing 16
chr2_-_224467142 4.171 NM_003469
SCG2
secretogranin II
chr1_-_40782981 4.135 COL9A2
collagen, type IX, alpha 2
chr10_-_64576123 4.083 NM_000399
NM_001136177
NM_001136179
EGR2


early growth response 2


chr10_-_64576074 4.076 EGR2
early growth response 2
chr1_+_18807423 4.075 NM_152375
KLHDC7A
kelch domain containing 7A
chr19_+_1753661 3.887 NM_001080488
ONECUT3
one cut homeobox 3
chr5_+_159614373 3.885 NM_001130958
FABP6
fatty acid binding protein 6, ileal
chr11_-_119234628 3.882 USP2
ubiquitin specific peptidase 2
chr17_-_34079896 3.856 NM_139285
GAS2L2
growth arrest-specific 2 like 2
chr1_-_22469414 3.833 NM_030761
WNT4
wingless-type MMTV integration site family, member 4
chr19_-_47164289 3.700 NM_145056
DACT3
dapper, antagonist of beta-catenin, homolog 3 (Xenopus laevis)
chrX_-_140336628 3.632 NM_022661
SPANXC
SPANX family, member C
chr11_+_1860718 3.612 NM_001145829
TNNI2
troponin I type 2 (skeletal, fast)
chr19_-_6375859 3.610 NM_004158
PSPN
persephin
chrX_-_102565805 3.587 NM_001168399
NM_001168400
NM_001168401
NM_032621
BEX2



brain expressed X-linked 2



chr19_+_41222915 3.583 NM_025194
ITPKC
inositol-trisphosphate 3-kinase C
chr1_-_92949500 3.520 GFI1
growth factor independent 1 transcription repressor
chr1_-_92949355 3.518 NM_001127215
GFI1
growth factor independent 1 transcription repressor
chr6_-_24911194 3.497 NM_014722
FAM65B
family with sequence similarity 65, member B
chr1_-_92949045 3.465 GFI1
growth factor independent 1 transcription repressor
chr2_-_101767714 3.421 NM_001102426
TBC1D8
TBC1 domain family, member 8 (with GRAM domain)
chr11_-_119252364 3.402 NM_001243759
NM_004205
USP2

ubiquitin specific peptidase 2

chr19_+_54385429 3.374 NM_002739
PRKCG
protein kinase C, gamma
chr5_-_11904127 3.367 CTNND2
catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein)
chr6_+_137243378 3.351 NM_001008783
SLC35D3
solute carrier family 35, member D3
chrX_+_150863729 3.349 NM_024082
PRRG3
proline rich Gla (G-carboxyglutamic acid) 3 (transmembrane)
chr14_-_67982020 3.342 NM_182526
TMEM229B
transmembrane protein 229B
chr19_+_41223282 3.331 ITPKC
inositol-trisphosphate 3-kinase C
chr9_+_92219926 3.315 NM_006705
GADD45G
growth arrest and DNA-damage-inducible, gamma
chr14_-_107199126 3.250 IGHG3
immunoglobulin heavy constant gamma 3 (G3m marker)
chr6_-_33714681 3.221 NM_001142883
NM_054111
IP6K3

inositol hexakisphosphate kinase 3

chr11_+_64107687 3.216 NM_032251
CCDC88B
coiled-coil domain containing 88B
chr22_-_22089975 3.210 NM_013313
YPEL1
yippee-like 1 (Drosophila)
chr3_+_85008031 3.206 NM_001167674
NM_001167675
CADM2

cell adhesion molecule 2

chr6_+_111408780 3.204 NM_018593
SLC16A10
solute carrier family 16, member 10 (aromatic amino acid transporter)
chr3_+_39851028 3.195 NM_015460
MYRIP
myosin VIIA and Rab interacting protein
chr12_-_63328663 3.122 NM_020700
PPM1H
protein phosphatase, Mg2+/Mn2+ dependent, 1H
chr20_+_43343523 3.116 WISP2
WNT1 inducible signaling pathway protein 2
chr11_-_2170792 3.115 NM_001007139
IGF2
insulin-like growth factor 2 (somatomedin A)
chr14_-_23288912 3.112 NM_001126106
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chrX_-_153775427 3.104 G6PD
glucose-6-phosphate dehydrogenase
chr11_-_124632050 3.088 NM_138961
ESAM
endothelial cell adhesion molecule
chrX_+_102470003 3.083 NM_001080425
NM_001127688
BEX4

brain expressed, X-linked 4

chr9_+_140918042 3.075 CACNA1B
calcium channel, voltage-dependent, N type, alpha 1B subunit
chrX_-_140672799 3.074 NM_013453
NM_145662
SPANXA1
SPANXA2
sperm protein associated with the nucleus, X-linked, family member A1
SPANX family, member A2
chr19_-_6199536 3.067


chr8_-_98290072 3.063 TSPYL5
TSPY-like 5
chr15_+_75118950 3.056 NM_001030005
CPLX3
complexin 3
chrX_-_140786561 3.032 NM_145665
NM_032417
SPANXE
SPANXD
SPANXA2
SPANX family, member E
SPANX family, member D
SPANX family, member A2
chr14_-_91526731 3.031


chr1_-_220101514 3.015 SLC30A10
solute carrier family 30, member 10
chr15_-_101084871 3.003 NM_178842
CERS3
ceramide synthase 3
chr22_-_37882214 2.988 NM_001166343
NM_002405
MFNG

MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase

chr2_+_24232952 2.974 NM_001080473
MFSD2B
major facilitator superfamily domain containing 2B
chr4_-_16085593 2.953 NM_001145847
NM_001145848
PROM1

prominin 1

chr11_-_130298305 2.952 ADAMTS8
ADAM metallopeptidase with thrombospondin type 1 motif, 8
chr19_-_18391440 2.948


chr9_-_91793375 2.947 SHC3
SHC (Src homology 2 domain containing) transforming protein 3
chr5_-_132948195 2.943 FSTL4
follistatin-like 4
chr20_+_37555055 2.929 FAM83D
family with sequence similarity 83, member D
chr1_-_151798552 2.927 NM_001001523
RORC
RAR-related orphan receptor C
chr11_-_119252267 2.920 USP2
ubiquitin specific peptidase 2
chr2_+_11682836 2.911 NM_033090
GREB1
growth regulation by estrogen in breast cancer 1
chr16_-_49315682 2.906 NM_004352
CBLN1
cerebellin 1 precursor
chr5_+_5140442 2.901 NM_139056
ADAMTS16
ADAM metallopeptidase with thrombospondin type 1 motif, 16
chr9_+_135937364 2.899 NM_001807
CEL
carboxyl ester lipase (bile salt-stimulated lipase)
chr13_+_33590477 2.886 NM_004795
KL
klotho
chr7_+_31003635 2.886 NM_000823
GHRHR
growth hormone releasing hormone receptor
chr3_+_150803448 2.884 MED12L
mediator complex subunit 12-like
chr2_-_178937472 2.881 NM_016953
PDE11A
phosphodiesterase 11A
chr6_+_96463844 2.862 NM_006581
FUT9
fucosyltransferase 9 (alpha (1,3) fucosyltransferase)
chr14_+_92788924 2.851 NM_153648
SLC24A4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr10_-_91295310 2.846 NM_213606
SLC16A12
solute carrier family 16, member 12 (monocarboxylic acid transporter 12)
chr9_+_138594030 2.804 NM_020822
KCNT1
potassium channel, subfamily T, member 1
chr6_+_168841829 2.803 NM_001166412
NM_022138
SMOC2

SPARC related modular calcium binding 2

chr1_-_32707198 2.803 MTMR9LP
myotubularin related protein 9-like, pseudogene
chr14_+_100150596 2.786 NM_006668
CYP46A1
cytochrome P450, family 46, subfamily A, polypeptide 1
chr10_-_73848766 2.771 NM_001134434
NM_014767
SPOCK2

sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2

chrX_-_20009037 2.767 LOC729609
uncharacterized LOC729609
chr17_+_4981754 2.765 ZFP3
zinc finger protein 3 homolog (mouse)
chr18_-_45935627 2.759 ZBTB7C
zinc finger and BTB domain containing 7C
chr10_-_73848530 2.755 NM_001244950
SPOCK2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr19_-_47137938 2.721 NM_033258
GNG8
guanine nucleotide binding protein (G protein), gamma 8
chr1_+_55271735 2.716 NM_001110533
NM_152607
C1orf177

chromosome 1 open reading frame 177

chr2_+_79740059 2.701 NM_001164883
NM_004389
CTNNA2

catenin (cadherin-associated protein), alpha 2

chr15_+_47476225 2.698 NM_001198999
SEMA6D
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
chr7_+_140103842 2.685 NM_001008749
RAB19
RAB19, member RAS oncogene family
chr10_+_99332197 2.677 NM_001129981
NM_020349
ANKRD2

ankyrin repeat domain 2 (stretch responsive muscle)

chr12_-_57351381 2.676 NM_003708
RDH16
retinol dehydrogenase 16 (all-trans)
chr22_-_21386837 2.669 NM_004173
SLC7A4
solute carrier family 7 (orphan transporter), member 4
chr5_+_95067511 2.654


chr7_-_150675236 2.646 NM_000238
NM_172056
KCNH2

potassium voltage-gated channel, subfamily H (eag-related), member 2

chr4_-_16085309 2.640 PROM1
prominin 1
chr11_+_2466171 2.628 NM_000218
KCNQ1
potassium voltage-gated channel, KQT-like subfamily, member 1
chr8_-_143867931 2.627 NM_003695
LY6D
lymphocyte antigen 6 complex, locus D
chrX_-_15402469 2.615 NM_004469
FIGF
c-fos induced growth factor (vascular endothelial growth factor D)
chrX_+_150345055 2.599 NM_004224
GPR50
G protein-coupled receptor 50
chr3_-_197807541 2.596 ANKRD18DP
ankyrin repeat domain 18D, pseudogene
chr11_-_35441099 2.588 NM_004171
SLC1A2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr6_-_28303910 2.578 NM_001135216
NM_001243243
ZNF323

zinc finger protein 323

chr16_+_56225250 2.567 NM_020988
NM_138736
GNAO1

guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O

chr1_-_161039413 2.566 ARHGAP30
Rho GTPase activating protein 30
chr1_-_16344438 2.552 HSPB7
heat shock 27kDa protein family, member 7 (cardiovascular)
chr17_+_4981721 2.549 NM_153018
ZFP3
zinc finger protein 3 homolog (mouse)
chr7_+_100136784 2.549 NM_006076
AGFG2
ArfGAP with FG repeats 2
chr6_+_168841873 2.519 SMOC2
SPARC related modular calcium binding 2
chr10_+_112257624 2.517 NM_004419
DUSP5
dual specificity phosphatase 5
chr16_+_23847271 2.500 NM_002738
NM_212535
PRKCB

protein kinase C, beta

chr9_-_139637354 2.490 NM_001001712
LCN10
lipocalin 10
chr11_-_130298502 2.475 NM_007037
ADAMTS8
ADAM metallopeptidase with thrombospondin type 1 motif, 8
chr19_-_460995 2.469 NM_012435
SHC2
SHC (Src homology 2 domain containing) transforming protein 2
chr7_-_37488894 2.451 NM_001206480
ELMO1
engulfment and cell motility 1
chr19_-_47734215 2.439 NM_014417
BBC3
BCL2 binding component 3
chr20_+_30407175 2.423 NM_033118
MYLK2
myosin light chain kinase 2
chr17_+_5972425 2.422 WSCD1
WSC domain containing 1
chr4_+_41362565 2.408 LIMCH1
LIM and calponin homology domains 1
chr16_+_1203240 2.408 NM_001005407
NM_021098
CACNA1H

calcium channel, voltage-dependent, T type, alpha 1H subunit

chr14_-_106237675 2.407 IGHM
immunoglobulin heavy constant mu
chr12_+_49524648 2.406


chr9_-_101470836 2.406 NM_005458
GABBR2
gamma-aminobutyric acid (GABA) B receptor, 2
chr1_+_118148506 2.405 NM_017709
FAM46C
family with sequence similarity 46, member C
chr2_+_198669316 2.380 NM_006226
PLCL1
phospholipase C-like 1
chr1_-_204120909 2.363 ETNK2
ethanolamine kinase 2
chr1_-_161039745 2.358 NM_001025598
NM_181720
ARHGAP30

Rho GTPase activating protein 30

chr16_-_30124829 2.354 NM_024307
GDPD3
glycerophosphodiester phosphodiesterase domain containing 3
chr2_-_128433330 2.342 LIMS2
LIM and senescent cell antigen-like domains 2
chr5_-_139422805 2.331 NM_001184935
NM_004883
NM_013981
NM_013982
NM_013983
NRG2




neuregulin 2




chrX_-_152939256 2.321 PNCK
pregnancy up-regulated non-ubiquitously expressed CaM kinase
chr22_+_21330361 2.318 AIFM3
apoptosis-inducing factor, mitochondrion-associated, 3
chr19_+_15751706 2.315 NM_000896
NM_001199208
NM_001199209
CYP4F3


cytochrome P450, family 4, subfamily F, polypeptide 3


chr11_+_7273400 2.305 SYT9
synaptotagmin IX
chr8_-_98290171 2.267 NM_033512
TSPYL5
TSPY-like 5
chr17_+_26800657 2.260 NM_001145975
NM_001145976
NM_003984
SLC13A2


solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2


chr20_+_37554954 2.258 NM_030919
FAM83D
family with sequence similarity 83, member D
chr11_-_86383164 2.251 NM_001014811
ME3
malic enzyme 3, NADP(+)-dependent, mitochondrial
chr12_+_49372235 2.251 NM_005430
WNT1
wingless-type MMTV integration site family, member 1
chr2_-_130956011 2.250 NM_207312
TUBA3E
tubulin, alpha 3e
chr2_+_234621637 2.246 NM_019078
UGT1A5
UDP glucuronosyltransferase 1 family, polypeptide A5
chr19_+_56158953 2.245 NM_013301
CCDC106
coiled-coil domain containing 106
chr4_-_159092509 2.245 FAM198B
family with sequence similarity 198, member B
chr11_-_2560814 2.243


chr2_+_234637772 2.241 NM_019093
UGT1A3
UDP glucuronosyltransferase 1 family, polypeptide A3
chr2_-_109605668 2.240 NM_022336
EDAR
ectodysplasin A receptor
chrX_+_140677834 2.233 NM_013453
NM_145662
SPANXA1
SPANXA2
sperm protein associated with the nucleus, X-linked, family member A1
SPANX family, member A2
chr14_-_107083398 2.226 IGH@
IGHA1
IGHG1
immunoglobulin heavy locus
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
chrX_-_153775064 2.198 NM_000402
G6PD
glucose-6-phosphate dehydrogenase
chr8_-_124553448 2.185 NM_001242463
NM_058229
FBXO32

F-box protein 32

chr7_+_100136845 2.167 AGFG2
ArfGAP with FG repeats 2
chrX_+_53111482 2.159 NM_022117
TSPYL2
TSPY-like 2
chr19_+_54926721 2.150 TTYH1
tweety homolog 1 (Drosophila)
chr10_+_133918312 2.144 NM_001105521
JAKMIP3
Janus kinase and microtubule interacting protein 3
chr8_-_57123858 2.143 NM_001114634
NM_001114635
NM_002655
PLAG1


pleiomorphic adenoma gene 1


chr11_+_1874199 2.139 NM_002339
LSP1
lymphocyte-specific protein 1
chrX_-_153775002 2.132 G6PD
glucose-6-phosphate dehydrogenase
chr16_+_2198687 2.122 RAB26
RAB26, member RAS oncogene family
chr8_-_57123827 2.121 PLAG1
pleiomorphic adenoma gene 1
chrX_+_124453968 2.120 NM_001195272
LOC100129520
testis expressed sequence 13-like
chr2_+_239047362 2.118 NM_198582
KLHL30
kelch-like 30 (Drosophila)
chr16_+_330605 2.115 NM_001176
ARHGDIG
Rho GDP dissociation inhibitor (GDI) gamma
chr3_+_140396865 2.110 NM_152616
TRIM42
tripartite motif containing 42
chr11_+_22214574 2.101 NM_001142649
NM_213599
ANO5

anoctamin 5

chr2_+_11680079 2.100 NM_148903
GREB1
growth regulation by estrogen in breast cancer 1
chr16_-_89007605 2.084 NM_175931
CBFA2T3
core-binding factor, runt domain, alpha subunit 2; translocated to, 3
chr10_+_123872440 2.084 TACC2
transforming, acidic coiled-coil containing protein 2
chr17_-_26692264 2.083 NM_001080837
SEBOX
SEBOX homeobox
chr11_+_117857123 2.078 IL10RA
interleukin 10 receptor, alpha
chr10_-_73848278 2.074 SPOCK2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr17_-_39216343 2.071 NM_001165252
LOC730755
keratin associated protein 2-4-like
chr1_-_9086403 2.066 NM_207420
SLC2A7
solute carrier family 2 (facilitated glucose transporter), member 7
chr1_+_201979689 2.065 NM_001114309
NM_004433
ELF3

E74-like factor 3 (ets domain transcription factor, epithelial-specific )

chr4_-_2366530 2.059 NM_001172659
NM_001172660
ZFYVE28

zinc finger, FYVE domain containing 28

chr12_-_63328857 2.057 PPM1H
protein phosphatase, Mg2+/Mn2+ dependent, 1H
chr17_-_39156106 2.056 NM_031959
KRTAP3-2
keratin associated protein 3-2
chr1_-_9189087 2.055 NM_024980
GPR157
G protein-coupled receptor 157
chr16_+_84178864 2.053 NM_178452
DNAAF1
dynein, axonemal, assembly factor 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
1.41 1.43e-07 GO:0032501 multicellular organismal process
1.54 4.78e-07 GO:0007275 multicellular organismal development
1.50 6.57e-07 GO:0032502 developmental process
1.56 9.57e-07 GO:0048856 anatomical structure development
1.74 9.79e-07 GO:0030154 cell differentiation
1.59 1.62e-06 GO:0048731 system development
1.70 2.68e-06 GO:0048869 cellular developmental process
2.26 6.38e-06 GO:0007267 cell-cell signaling
2.00 1.89e-04 GO:0048468 cell development
1.94 2.50e-04 GO:0007154 cell communication
2.50 3.40e-04 GO:0007268 synaptic transmission
2.35 8.85e-04 GO:0019226 transmission of nerve impulse
2.35 8.85e-04 GO:0035637 multicellular organismal signaling
2.64 1.51e-03 GO:0044057 regulation of system process
1.93 1.57e-03 GO:0006811 ion transport
4.25 1.64e-03 GO:0021700 developmental maturation
1.67 3.59e-03 GO:0007399 nervous system development
1.90 4.83e-03 GO:0048699 generation of neurons
1.82 1.37e-02 GO:0022008 neurogenesis
1.61 1.74e-02 GO:0009653 anatomical structure morphogenesis
1.34 2.37e-02 GO:0023052 signaling

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
1.40 8.17e-06 GO:0005886 plasma membrane
1.39 9.88e-06 GO:0071944 cell periphery
1.59 2.10e-05 GO:0044459 plasma membrane part
1.53 6.06e-04 GO:0005576 extracellular region
1.69 8.91e-04 GO:0031226 intrinsic to plasma membrane
1.68 1.60e-03 GO:0005887 integral to plasma membrane
2.65 1.08e-02 GO:0034702 ion channel complex
1.22 4.53e-02 GO:0031224 intrinsic to membrane

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
1.98 8.04e-05 GO:0022891 substrate-specific transmembrane transporter activity
1.89 2.41e-04 GO:0022857 transmembrane transporter activity
2.01 3.10e-04 GO:0015075 ion transmembrane transporter activity
2.38 7.75e-04 GO:0022838 substrate-specific channel activity
2.35 1.46e-03 GO:0005216 ion channel activity
2.31 1.54e-03 GO:0015267 channel activity
2.30 1.63e-03 GO:0022803 passive transmembrane transporter activity
2.06 3.00e-03 GO:0008324 cation transmembrane transporter activity
1.75 3.02e-03 GO:0022892 substrate-specific transporter activity
3.14 3.89e-03 GO:0008083 growth factor activity
1.64 8.66e-03 GO:0005215 transporter activity
5.25 4.29e-02 GO:0003823 antigen binding