Motif ID: MAFB.p2

Z-value: 1.614


Transcription factors associated with MAFB.p2:

Gene SymbolEntrez IDGene Name
MAFB 9935 v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian)

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
MAFBhg19_v1_chr20_-_39317875_39317880-0.171.5e-01Click!


Activity profile for motif MAFB.p2.

activity profile for motif MAFB.p2


Sorted Z-values histogram for motif MAFB.p2

Sorted Z-values for motif MAFB.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MAFB.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_-_76425207 7.937 PHLDA1
pleckstrin homology-like domain, family A, member 1
chr8_-_22550456 7.836 EGR3
early growth response 3
chr8_-_22550708 7.410 NM_004430
EGR3
early growth response 3
chr4_-_57522469 7.134 NM_001145459
NM_139211
HOPX

HOP homeobox

chr12_-_53074172 6.949 NM_006121
KRT1
keratin 1
chr4_-_57522059 5.735 HOPX
HOP homeobox
chr7_+_145813452 5.650 NM_014141
CNTNAP2
contactin associated protein-like 2
chr12_-_53242716 5.640 NM_173352
KRT78
keratin 78
chr16_-_49315682 5.189 NM_004352
CBLN1
cerebellin 1 precursor
chr11_+_129245834 5.183 NM_003658
BARX2
BARX homeobox 2
chr2_+_217498205 4.717 IGFBP2
insulin-like growth factor binding protein 2, 36kDa
chr8_-_22550057 4.677 NM_001199881
EGR3
early growth response 3
chr17_+_56065408 4.675


chr17_-_39203423 4.392 NM_001123387
KRTAP2-1
keratin associated protein 2-1
chrX_+_147582133 4.336 NM_001169122
NM_001169123
NM_001169124
NM_001169125
NM_002025
AFF2




AF4/FMR2 family, member 2




chr17_-_39211462 4.065 NM_033032
KRTAP2-2
keratin associated protein 2-2
chr19_+_15160194 4.038 NM_012114
CASP14
caspase 14, apoptosis-related cysteine peptidase
chr4_-_57547845 4.021 NM_001145460
NM_032495
NM_139212
HOPX


HOP homeobox


chr12_-_76425375 4.021 NM_007350
PHLDA1
pleckstrin homology-like domain, family A, member 1
chr2_+_176957448 3.982 NM_000523
HOXD13
homeobox D13
chr17_-_39216343 3.964 NM_001165252
LOC730755
keratin associated protein 2-4-like
chr2_+_105471745 3.831 NM_006236
POU3F3
POU class 3 homeobox 3
chr1_-_153363544 3.719 NM_002964
S100A8
S100 calcium binding protein A8
chr1_+_63788729 3.716 NM_012183
FOXD3
forkhead box D3
chr1_-_166135978 3.703


chr6_+_107811272 3.665 NM_018013
SOBP
sine oculis binding protein homolog (Drosophila)
chr10_-_133109808 3.579 TCERG1L
transcription elongation regulator 1-like
chr1_-_99470177 3.530 NM_001010861
NM_001037317
LPPR5

lipid phosphate phosphatase-related protein type 5

chr6_+_43139201 3.407 SRF
serum response factor (c-fos serum response element-binding transcription factor)
chr9_+_102584136 3.375 NM_006981
NM_173199
NM_173200
NR4A3


nuclear receptor subfamily 4, group A, member 3


chr17_-_39280377 3.370 NM_031854
KRTAP4-12
keratin associated protein 4-12
chr11_-_61348290 3.315 NM_001252065
NM_004200
SYT7

synaptotagmin VII

chr5_-_139725860 3.273 HBEGF
heparin-binding EGF-like growth factor
chr6_+_43139190 3.261 SRF
serum response factor (c-fos serum response element-binding transcription factor)
chr10_-_61122219 3.214 NM_001001971
NM_001166698
NM_198215
FAM13C


family with sequence similarity 13, member C


chr10_-_133109983 3.151 NM_174937
TCERG1L
transcription elongation regulator 1-like
chr13_-_26625164 3.123 NM_001007538
SHISA2
shisa homolog 2 (Xenopus laevis)
chr6_+_43138919 3.065 NM_003131
SRF
serum response factor (c-fos serum response element-binding transcription factor)
chr10_-_99790584 3.060 NM_001206528
NM_018058
CRTAC1

cartilage acidic protein 1

chr17_+_28256873 3.045 NM_001145053
EFCAB5
EF-hand calcium binding domain 5
chr15_-_90039776 3.034 NM_016321
RHCG
Rh family, C glycoprotein
chr15_-_100882105 2.995 NM_139057
ADAMTS17
ADAM metallopeptidase with thrombospondin type 1 motif, 17
chr2_-_193059249 2.956 TMEFF2
transmembrane protein with EGF-like and two follistatin-like domains 2
chr1_-_223537400 2.876 NM_001037175
NM_017982
SUSD4

sushi domain containing 4

chr4_+_174292100 2.865 SAP30
Sin3A-associated protein, 30kDa
chr18_-_56296188 2.841 NM_052947
ALPK2
alpha-kinase 2
chrX_+_68725077 2.834 NM_015686
FAM155B
family with sequence similarity 155, member B
chr17_-_39222126 2.813 NM_033184
KRTAP2-4
keratin associated protein 2-4
chr5_-_139726173 2.790 NM_001945
HBEGF
heparin-binding EGF-like growth factor
chr2_+_217498082 2.782 NM_000597
IGFBP2
insulin-like growth factor binding protein 2, 36kDa
chr5_-_95297597 2.744 NM_012081
ELL2
elongation factor, RNA polymerase II, 2
chr17_-_50235670 2.706 CA10
carbonic anhydrase X
chr1_-_19282773 2.692 NM_001136265
IFFO2
intermediate filament family orphan 2
chr6_+_99282597 2.684 POU3F2
POU class 3 homeobox 2
chr14_-_27066959 2.678 NM_002515
NM_006489
NM_006491
NOVA1


neuro-oncological ventral antigen 1


chr8_-_22549901 2.676 NM_001199880
EGR3
early growth response 3
chr2_+_26915390 2.634 NM_002246
KCNK3
potassium channel, subfamily K, member 3
chr12_-_95044205 2.600 NM_020698
TMCC3
transmembrane and coiled-coil domain family 3
chr11_+_65657874 2.595 NM_006848
CCDC85B
coiled-coil domain containing 85B
chrX_+_152760346 2.583 NM_001711
BGN
biglycan
chr10_+_5566923 2.581 NM_005185
CALML3
calmodulin-like 3
chr3_-_10547221 2.540 ATP2B2
ATPase, Ca++ transporting, plasma membrane 2
chr2_+_176972005 2.479 NM_021192
HOXD11
homeobox D11
chr6_+_99282579 2.473 NM_005604
POU3F2
POU class 3 homeobox 2
chr16_+_2521499 2.460 NM_006181
NTN3
netrin 3
chr16_+_69139466 2.454 NM_001199280
HAS3
hyaluronan synthase 3
chr2_-_100721128 2.453 AFF3
AF4/FMR2 family, member 3
chr5_-_141704468 2.445 SPRY4
sprouty homolog 4 (Drosophila)
chr17_+_70117177 2.437 SOX9
SRY (sex determining region Y)-box 9
chr7_-_27239724 2.430 NM_000522
HOXA13
homeobox A13
chr11_+_123431036 2.423 GRAMD1B
GRAM domain containing 1B
chr1_-_31230594 2.420 LAPTM5
lysosomal protein transmembrane 5
chr20_-_23030141 2.414 NM_000361
THBD
thrombomodulin
chr4_+_174292027 2.411 NM_003864
SAP30
Sin3A-associated protein, 30kDa
chrX_-_47479229 2.410 NM_006950
NM_133499
SYN1

synapsin I

chr5_-_141704575 2.404 NM_001127496
NM_030964
SPRY4

sprouty homolog 4 (Drosophila)

chr6_+_72596648 2.395 NM_014989
RIMS1
regulating synaptic membrane exocytosis 1
chr12_-_45269340 2.388 NM_001145109
NELL2
NEL-like 2 (chicken)
chr1_+_63789044 2.373 FOXD3
forkhead box D3
chr19_-_13617037 2.372 NM_000068
NM_001127221
NM_001127222
NM_001174080
NM_023035
CACNA1A




calcium channel, voltage-dependent, P/Q type, alpha 1A subunit




chr8_+_65493610 2.367 BHLHE22
basic helix-loop-helix family, member e22
chr21_+_15588465 2.365 NM_144770
RBM11
RNA binding motif protein 11
chr5_+_113698304 2.364 KCNN2
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
chr16_+_9185571 2.361 C16orf72
chromosome 16 open reading frame 72
chr20_+_20348744 2.343 NM_002196
INSM1
insulinoma-associated 1
chr12_-_52828105 2.332 NM_004693
KRT75
keratin 75
chr15_-_53082087 2.314 NM_004498
ONECUT1
one cut homeobox 1
chr3_-_10547340 2.296 ATP2B2
ATPase, Ca++ transporting, plasma membrane 2
chr11_+_65658101 2.289 CCDC85B
coiled-coil domain containing 85B
chr1_-_22469414 2.274 NM_030761
WNT4
wingless-type MMTV integration site family, member 4
chr16_-_28074776 2.268 NM_001109763
GSG1L
GSG1-like
chr11_+_47608229 2.248 NM_001164379
FAM180B
family with sequence similarity 180, member B
chr4_+_7194317 2.237 NM_020777
SORCS2
sortilin-related VPS10 domain containing receptor 2
chr10_+_83635069 2.233 NM_001010848
NM_001165972
NRG3

neuregulin 3

chr12_-_45270071 2.226 NELL2
NEL-like 2 (chicken)
chr10_-_79397470 2.217 KCNMA1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr12_-_53207843 2.216 NM_002272
KRT4
keratin 4
chr1_-_31230673 2.208 NM_006762
LAPTM5
lysosomal protein transmembrane 5
chr11_+_66188474 2.206 NM_178864
NPAS4
neuronal PAS domain protein 4
chr12_-_132905781 2.204 NM_001122636
GALNT9
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 9 (GalNAc-T9)
chr8_-_103667882 2.201 NM_005655
KLF10
Kruppel-like factor 10
chrX_-_74145280 2.200 NM_001008537
KIAA2022
KIAA2022
chr19_-_36019194 2.188 NM_001166034
NM_001166035
NM_198538
SBSN


suprabasin


chr13_-_79177682 2.182 NM_006237
POU4F1
POU class 4 homeobox 1
chr1_+_11539177 2.179 NM_020780
PTCHD2
patched domain containing 2
chr12_-_63328857 2.175 PPM1H
protein phosphatase, Mg2+/Mn2+ dependent, 1H
chr16_+_69141442 2.175 NM_005329
HAS3
hyaluronan synthase 3
chr16_+_86544233 2.170 FOXF1
forkhead box F1
chr17_+_39240412 2.160 NM_033061
KRTAP4-7
keratin associated protein 4-7
chr15_-_83240499 2.154 NM_001079533
NM_001079534
NM_001079535
CPEB1


cytoplasmic polyadenylation element binding protein 1


chr2_+_24299670 2.152


chr12_-_76424474 2.146 PHLDA1
pleckstrin homology-like domain, family A, member 1
chr2_-_100720934 2.143 AFF3
AF4/FMR2 family, member 3
chr7_+_43622638 2.142 NM_004760
STK17A
serine/threonine kinase 17a
chr18_+_8609407 2.136 NM_001025300
RAB12
RAB12, member RAS oncogene family
chr18_+_55102777 2.134 NM_004852
ONECUT2
one cut homeobox 2
chr1_-_241520384 2.128 RGS7
regulator of G-protein signaling 7
chrX_-_110513750 2.119 NM_014289
CAPN6
calpain 6
chr1_-_201346804 2.115 NM_000364
NM_001001430
NM_001001431
NM_001001432
TNNT2



troponin T type 2 (cardiac)



chr17_-_39092714 2.098 KRT23
keratin 23 (histone deacetylase inducible)
chr4_-_174450529 2.096 HAND2
heart and neural crest derivatives expressed 2
chr11_+_123430935 2.089 GRAMD1B
GRAM domain containing 1B
chr17_-_27332888 2.085 NM_001098635
NM_178860
SEZ6

seizure related 6 homolog (mouse)

chr1_+_40839368 2.085 NM_022733
SMAP2
small ArfGAP2
chr1_-_241520467 2.082 NM_002924
RGS7
regulator of G-protein signaling 7
chrX_-_25031177 2.079 ARX
aristaless related homeobox
chr17_+_79860071 2.078 NM_148896
NPB
neuropeptide B
chr7_-_137531585 2.075 NM_004717
DGKI
diacylglycerol kinase, iota
chr6_-_166401526 2.067 LINC00473
long intergenic non-protein coding RNA 473
chr12_-_63328663 2.039 NM_020700
PPM1H
protein phosphatase, Mg2+/Mn2+ dependent, 1H
chr19_-_40724272 2.037 NM_152479
TTC9B
tetratricopeptide repeat domain 9B
chr18_-_22931970 2.031 ZNF521
zinc finger protein 521
chr11_-_106888829 2.029 NM_000855
GUCY1A2
guanylate cyclase 1, soluble, alpha 2
chr10_+_124895566 2.002 NM_001105574
HMX3
H6 family homeobox 3
chr2_+_17721806 1.997 NM_003385
VSNL1
visinin-like 1
chr4_-_174450343 1.991 HAND2
heart and neural crest derivatives expressed 2
chr6_+_32936375 1.984


chr13_-_72440557 1.980 DACH1
dachshund homolog 1 (Drosophila)
chr1_-_201346783 1.978 TNNT2
troponin T type 2 (cardiac)
chr10_-_61122660 1.968 NM_001143773
FAM13C
family with sequence similarity 13, member C
chr15_+_81293286 1.967 NM_022566
MESDC1
mesoderm development candidate 1
chr2_+_17721983 1.962 VSNL1
visinin-like 1
chr5_-_95297424 1.961 ELL2
elongation factor, RNA polymerase II, 2
chr10_-_99790346 1.960 CRTAC1
cartilage acidic protein 1
chrX_-_47479095 1.959


chr19_-_31840118 1.945 NM_020856
TSHZ3
teashirt zinc finger homeobox 3
chrX_+_128913881 1.945 NM_018990
SASH3
SAM and SH3 domain containing 3
chr13_+_35516390 1.942 NM_015678
NBEA
neurobeachin
chr15_-_72612127 1.938 CELF6
CUGBP, Elav-like family member 6
chr13_-_108519459 1.934 NM_001080396
FAM155A
family with sequence similarity 155, member A
chr8_-_143867931 1.932 NM_003695
LY6D
lymphocyte antigen 6 complex, locus D
chr8_-_95274540 1.929 NM_005261
NM_181702
GEM

GTP binding protein overexpressed in skeletal muscle

chr14_+_79745653 1.928 NM_001105250
NM_138970
NRXN3

neurexin 3

chr1_-_200379165 1.921 NM_012482
ZNF281
zinc finger protein 281
chr9_+_130854127 1.916 NM_001006642
SLC25A25
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25
chr11_-_2193015 1.897 NM_000360
NM_199292
NM_199293
TH


tyrosine hydroxylase


chr10_-_131762017 1.895 NM_001005463
EBF3
early B-cell factor 3
chrX_+_152760452 1.884 BGN
biglycan
chr5_+_137801178 1.884 NM_001964
EGR1
early growth response 1
chr14_-_91526731 1.880


chr11_+_73087670 1.880 NM_032871
RELT
RELT tumor necrosis factor receptor
chr13_+_28366779 1.879 NM_145657
GSX1
GS homeobox 1
chr12_-_89745753 1.877 DUSP6
dual specificity phosphatase 6
chr16_+_87636492 1.877 NM_020655
JPH3
junctophilin 3
chr2_+_176987412 1.870 NM_014213
HOXD9
homeobox D9
chr11_-_45928832 1.868 NM_001080446
C11orf94
chromosome 11 open reading frame 94
chr11_-_64646053 1.861 NM_006795
EHD1
EH-domain containing 1
chr3_-_10547267 1.861 NM_001001331
NM_001683
ATP2B2

ATPase, Ca++ transporting, plasma membrane 2

chr2_+_191745568 1.851 GLS
glutaminase
chr20_+_43803539 1.851 NM_002638
PI3
peptidase inhibitor 3, skin-derived
chr1_-_223853359 1.843 CAPN8
calpain 8
chrX_-_83442906 1.838 NM_014496
RPS6KA6
ribosomal protein S6 kinase, 90kDa, polypeptide 6
chr10_-_79397394 1.833 KCNMA1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr18_-_22932109 1.827 NM_015461
ZNF521
zinc finger protein 521
chr7_+_155250705 1.824 NM_001427
EN2
engrailed homeobox 2
chr17_+_30813928 1.821 NM_003885
CDK5R1
cyclin-dependent kinase 5, regulatory subunit 1 (p35)
chr19_-_10121041 1.819 NM_015719
COL5A3
collagen, type V, alpha 3
chr1_-_223853400 1.817 NM_001143962
CAPN8
calpain 8
chr6_-_166401403 1.810 LINC00473
long intergenic non-protein coding RNA 473
chr1_+_39456887 1.809 NM_001136275
NM_024595
AKIRIN1

akirin 1

chr19_+_13263890 1.808 IER2
immediate early response 2
chr14_+_23511375 1.804 NM_001099780
PSMB11
proteasome (prosome, macropain) subunit, beta type, 11
chr11_-_64645925 1.803 EHD1
EH-domain containing 1
chr8_+_85095702 1.798 RALYL
RALY RNA binding protein-like
chr3_-_50649080 1.794 CISH
cytokine inducible SH2-containing protein
chr4_-_103422436 1.788


chr7_+_28448970 1.784 LOC401317
uncharacterized LOC401317
chr18_-_5543967 1.780 NM_012307
EPB41L3
erythrocyte membrane protein band 4.1-like 3
chr6_-_84418492 1.774 SNAP91
synaptosomal-associated protein, 91kDa homolog (mouse)
chr17_-_31620005 1.772 NM_183377
ACCN1
amiloride-sensitive cation channel 1, neuronal
chr1_+_40839429 1.771 SMAP2
small ArfGAP2
chr17_-_7518124 1.760 NM_004860
FXR2
fragile X mental retardation, autosomal homolog 2
chr6_+_72596405 1.741 RIMS1
regulating synaptic membrane exocytosis 1
chr1_-_165414499 1.725 NM_006917
RXRG
retinoid X receptor, gamma
chr3_+_109128836 1.723 NM_001145553
FLJ25363
uncharacterized LOC401082
chr7_-_139876718 1.718 NM_030647
JHDM1D
jumonji C domain containing histone demethylase 1 homolog D (S. cerevisiae)
chr15_+_33603162 1.715 NM_001036
NM_001243996
RYR3

ryanodine receptor 3

chr12_+_103352021 1.708 ASCL1
achaete-scute complex homolog 1 (Drosophila)
chr15_-_65670325 1.708 NM_004884
IGDCC3
immunoglobulin superfamily, DCC subclass, member 3
chrX_+_72223351 1.705 NM_001042506
PABPC1L2B
poly(A) binding protein, cytoplasmic 1-like 2B

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
1.94 2.82e-14 GO:0007275 multicellular organismal development
4.05 4.42e-13 GO:0007417 central nervous system development
1.84 7.91e-13 GO:0032502 developmental process
1.98 6.49e-12 GO:0048731 system development
2.26 2.24e-11 GO:0048513 organ development
1.90 2.39e-11 GO:0048856 anatomical structure development
4.40 5.82e-11 GO:0007420 brain development
2.43 7.81e-11 GO:0007399 nervous system development
3.78 4.02e-10 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
1.58 9.10e-10 GO:0032501 multicellular organismal process
3.11 4.03e-08 GO:0045893 positive regulation of transcription, DNA-dependent
2.58 8.10e-08 GO:0006357 regulation of transcription from RNA polymerase II promoter
2.00 8.90e-08 GO:0030154 cell differentiation
2.97 1.16e-07 GO:0051254 positive regulation of RNA metabolic process
2.94 1.61e-07 GO:0010628 positive regulation of gene expression
1.94 3.86e-07 GO:0048869 cellular developmental process
2.61 5.87e-07 GO:0009888 tissue development
2.55 6.34e-07 GO:0048468 cell development
2.67 2.12e-06 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
3.99 3.39e-06 GO:0035295 tube development
2.66 3.71e-06 GO:0010557 positive regulation of macromolecule biosynthetic process
5.32 4.59e-06 GO:0045165 cell fate commitment
2.59 5.52e-06 GO:0051173 positive regulation of nitrogen compound metabolic process
2.42 1.09e-05 GO:0022008 neurogenesis
2.66 1.36e-05 GO:0030182 neuron differentiation
9.72 1.61e-05 GO:0007422 peripheral nervous system development
2.47 1.69e-05 GO:0031328 positive regulation of cellular biosynthetic process
2.79 2.06e-05 GO:0009887 organ morphogenesis
2.43 2.86e-05 GO:0009891 positive regulation of biosynthetic process
2.42 3.49e-05 GO:0048699 generation of neurons
1.31 4.46e-05 GO:0065007 biological regulation
1.33 5.30e-05 GO:0050789 regulation of biological process
4.58 5.60e-05 GO:0030900 forebrain development
3.21 1.00e-04 GO:0060429 epithelium development
2.55 1.04e-04 GO:0009790 embryo development
1.33 2.71e-04 GO:0050794 regulation of cellular process
1.93 3.40e-04 GO:0009653 anatomical structure morphogenesis
9.17 6.07e-04 GO:0021987 cerebral cortex development
6.19 7.04e-04 GO:0021953 central nervous system neuron differentiation
5.56 8.61e-04 GO:0030324 lung development
3.29 9.75e-04 GO:0048729 tissue morphogenesis
2.22 1.12e-03 GO:0006351 transcription, DNA-dependent
1.68 1.21e-03 GO:0051252 regulation of RNA metabolic process
2.03 1.22e-03 GO:0010604 positive regulation of macromolecule metabolic process
5.38 1.25e-03 GO:0030323 respiratory tube development
1.93 2.84e-03 GO:0051239 regulation of multicellular organismal process
1.97 2.88e-03 GO:0031325 positive regulation of cellular metabolic process
2.57 5.57e-03 GO:0019226 transmission of nerve impulse
2.57 5.57e-03 GO:0035637 multicellular organismal signaling
2.97 5.63e-03 GO:0045597 positive regulation of cell differentiation
4.66 6.60e-03 GO:0060541 respiratory system development
1.46 6.84e-03 GO:0023052 signaling
1.90 7.14e-03 GO:0009893 positive regulation of metabolic process
2.08 7.32e-03 GO:0050793 regulation of developmental process
2.20 7.50e-03 GO:0007267 cell-cell signaling
2.27 9.34e-03 GO:0045595 regulation of cell differentiation
2.80 9.60e-03 GO:0048598 embryonic morphogenesis
1.63 1.18e-02 GO:0006355 regulation of transcription, DNA-dependent
3.34 1.27e-02 GO:0002009 morphogenesis of an epithelium
2.38 1.32e-02 GO:0048666 neuron development
3.64 1.41e-02 GO:0030855 epithelial cell differentiation
8.97 1.42e-02 GO:0050885 neuromuscular process controlling balance
6.39 1.48e-02 GO:0021543 pallium development
2.00 1.62e-02 GO:0032774 RNA biosynthetic process
3.98 1.83e-02 GO:0001655 urogenital system development
3.36 2.10e-02 GO:0043193 positive regulation of gene-specific transcription
2.90 2.13e-02 GO:0007610 behavior
3.51 2.16e-02 GO:0048732 gland development
4.86 2.37e-02 GO:0021537 telencephalon development
2.53 2.43e-02 GO:0051094 positive regulation of developmental process
1.54 2.69e-02 GO:0010468 regulation of gene expression
2.77 2.75e-02 GO:0007389 pattern specification process
1.56 3.01e-02 GO:2000112 regulation of cellular macromolecule biosynthetic process
7.73 4.03e-02 GO:0021536 diencephalon development
1.92 4.10e-02 GO:0007154 cell communication
2.50 4.31e-02 GO:0032583 regulation of gene-specific transcription
2.49 4.49e-02 GO:0007268 synaptic transmission
1.54 4.59e-02 GO:0010556 regulation of macromolecule biosynthetic process
1.51 4.63e-02 GO:0048518 positive regulation of biological process
4.97 4.72e-02 GO:0060485 mesenchyme development

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
5.82 2.00e-04 GO:0045095 keratin filament
2.66 1.36e-03 GO:0045202 synapse
3.53 5.37e-03 GO:0005882 intermediate filament
2.95 9.96e-03 GO:0005667 transcription factor complex
3.06 2.76e-02 GO:0045111 intermediate filament cytoskeleton

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
3.01 9.83e-15 GO:0030528 transcription regulator activity
3.40 4.87e-13 GO:0043565 sequence-specific DNA binding
2.74 5.59e-11 GO:0001071 nucleic acid binding transcription factor activity
2.74 5.59e-11 GO:0003700 sequence-specific DNA binding transcription factor activity
3.88 4.84e-06 GO:0003702 RNA polymerase II transcription factor activity
3.89 1.43e-04 GO:0010843 promoter binding
3.74 2.66e-04 GO:0000975 regulatory region DNA binding
3.74 2.66e-04 GO:0001067 regulatory region nucleic acid binding
3.74 2.66e-04 GO:0044212 transcription regulatory region DNA binding
1.50 5.67e-04 GO:0003676 nucleic acid binding
1.63 6.55e-04 GO:0003677 DNA binding
2.84 3.61e-03 GO:0016563 transcription activator activity
4.86 4.64e-03 GO:0003704 specific RNA polymerase II transcription factor activity
4.70 6.35e-03 GO:0000981 sequence-specific DNA binding RNA polymerase II transcription factor activity
4.73 1.41e-02 GO:0003705 sequence-specific enhancer binding RNA polymerase II transcription factor activity
2.65 2.34e-02 GO:0016564 transcription repressor activity