Motif ID: IKZF1.p2

Z-value: 1.215


Transcription factors associated with IKZF1.p2:

Gene SymbolEntrez IDGene Name
IKZF1 10320 IKAROS family zinc finger 1 (Ikaros)



Activity profile for motif IKZF1.p2.

activity profile for motif IKZF1.p2


Sorted Z-values histogram for motif IKZF1.p2

Sorted Z-values for motif IKZF1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of IKZF1.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr15_-_42448769 15.702 NM_213600
PLA2G4F
phospholipase A2, group IVF
chr6_+_126070813 12.032 HEY2
hairy/enhancer-of-split related with YRPW motif 2
chr6_+_126070895 9.206 HEY2
hairy/enhancer-of-split related with YRPW motif 2
chr4_-_57522059 6.320 HOPX
HOP homeobox
chr1_-_109849613 5.710 NM_001010985
MYBPHL
myosin binding protein H-like
chr6_+_126070724 5.702 NM_012259
HEY2
hairy/enhancer-of-split related with YRPW motif 2
chr6_+_126070738 5.575 HEY2
hairy/enhancer-of-split related with YRPW motif 2
chr19_-_36019194 5.032 NM_001166034
NM_001166035
NM_198538
SBSN


suprabasin


chr10_-_5541401 4.966 NM_017422
CALML5
calmodulin-like 5
chr17_+_38474513 4.653 RARA
retinoic acid receptor, alpha
chr17_+_38474544 4.434 RARA
retinoic acid receptor, alpha
chr19_-_51456159 4.002 NM_001077491
NM_001077492
NM_012427
KLK5


kallikrein-related peptidase 5


chr14_+_79745653 3.876 NM_001105250
NM_138970
NRXN3

neurexin 3

chr9_+_138453599 3.842 NM_001018049
NM_002571
PAEP

progestagen-associated endometrial protein

chr17_-_3461030 3.238 TRPV3
transient receptor potential cation channel, subfamily V, member 3
chrX_+_115567820 3.190 SLC6A14
solute carrier family 6 (amino acid transporter), member 14
chr12_+_41086189 3.161 NM_001843
NM_175038
CNTN1

contactin 1

chrX_+_115567746 3.119 NM_007231
SLC6A14
solute carrier family 6 (amino acid transporter), member 14
chr9_-_21994414 3.087 NM_058195
CDKN2A
cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)
chr9_+_17578952 3.034 NM_003026
SH3GL2
SH3-domain GRB2-like 2
chr9_-_21994329 3.005 CDKN2A
cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)
chr19_+_42259397 3.004 NM_002483
CEACAM6
carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
chr11_-_2018703 2.986 H19
H19, imprinted maternally expressed transcript (non-protein coding)
chr2_+_17721983 2.974 VSNL1
visinin-like 1
chr7_+_148036528 2.763 CNTNAP2
contactin associated protein-like 2
chr2_+_17721806 2.750 NM_003385
VSNL1
visinin-like 1
chr22_+_37257004 2.743 NM_000631
NM_013416
NCF4

neutrophil cytosolic factor 4, 40kDa

chr13_-_36429798 2.690 NM_001195415
NM_001195416
NM_001195430
DCLK1


doublecortin-like kinase 1


chr15_+_75118950 2.647 NM_001030005
CPLX3
complexin 3
chr12_-_58160823 2.628 NM_000785
CYP27B1
cytochrome P450, family 27, subfamily B, polypeptide 1
chr19_+_496453 2.624 NM_130760
NM_130762
MADCAM1

mucosal vascular addressin cell adhesion molecule 1

chr9_-_21994379 2.578 CDKN2A
cyclin-dependent kinase inhibitor 2A (melanoma, p16, inhibits CDK4)
chr4_-_57547845 2.515 NM_001145460
NM_032495
NM_139212
HOPX


HOP homeobox


chr7_-_148581403 2.491 NM_001203247
NM_001203248
NM_004456
NM_152998
EZH2



enhancer of zeste homolog 2 (Drosophila)



chr1_+_160336856 2.445 NM_005598
NHLH1
nescient helix loop helix 1
chr17_+_38474472 2.423 NM_001145301
NM_001145302
RARA

retinoic acid receptor, alpha

chr7_+_47694841 2.384 NM_001123065
C7orf65
chromosome 7 open reading frame 65
chr7_-_148581379 2.379 EZH2
enhancer of zeste homolog 2 (Drosophila)
chr1_+_15250578 2.370 NM_001018000
KAZN
kazrin, periplakin interacting protein
chr22_-_19512859 2.363 NM_001130861
NM_003277
CLDN5

claudin 5

chr4_+_159690208 2.351 FNIP2
folliculin interacting protein 2
chr12_-_45307710 2.333 NM_001145110
NELL2
NEL-like 2 (chicken)
chr19_+_46801632 2.248 NM_022462
NM_152796
HIF3A

hypoxia inducible factor 3, alpha subunit

chr3_+_127634317 2.222 KBTBD12
kelch repeat and BTB (POZ) domain containing 12
chr2_-_224467095 2.179 SCG2
secretogranin II
chr20_+_56136136 2.091 NM_002591
PCK1
phosphoenolpyruvate carboxykinase 1 (soluble)
chr17_+_38465422 2.089 NM_000964
RARA
retinoic acid receptor, alpha
chr1_+_113263188 2.089 NM_001004440
NM_182759
FAM19A3

family with sequence similarity 19 (chemokine (C-C motif)-like), member A3

chr2_+_102608305 2.067 NM_004633
IL1R2
interleukin 1 receptor, type II
chr7_-_148581377 2.036 EZH2
enhancer of zeste homolog 2 (Drosophila)
chr7_-_148581297 2.007 EZH2
enhancer of zeste homolog 2 (Drosophila)
chr8_-_70747200 1.994 NM_030958
SLCO5A1
solute carrier organic anion transporter family, member 5A1
chr9_-_33447527 1.975 NM_004925
AQP3
aquaporin 3 (Gill blood group)
chr1_-_152386727 1.974 NM_016190
CRNN
cornulin
chr16_-_66952729 1.971 NM_001204744
NM_001204745
NM_001204746
NM_004062
CDH16



cadherin 16, KSP-cadherin



chr2_-_224467142 1.943 NM_003469
SCG2
secretogranin II
chr2_-_224467049 1.935 SCG2
secretogranin II
chr7_+_23286386 1.922 GPNMB
glycoprotein (transmembrane) nmb
chr7_-_148581359 1.921 EZH2
enhancer of zeste homolog 2 (Drosophila)
chr7_+_33945111 1.918 NM_133468
BMPER
BMP binding endothelial regulator
chr4_+_81256873 1.909 NM_001206997
NM_152770
C4orf22

chromosome 4 open reading frame 22

chr17_-_39646115 1.895 NM_003771
KRT36
keratin 36
chr17_+_38119225 1.893 NM_178171
GSDMA
gasdermin A
chr19_-_10121041 1.891 NM_015719
COL5A3
collagen, type V, alpha 3
chr5_-_95018659 1.889 NM_031952
SPATA9
spermatogenesis associated 9
chr2_+_16080639 1.887 NM_005378
MYCN
v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)
chr19_+_49109999 1.881 NM_133498
SPACA4
sperm acrosome associated 4
chr10_+_85933553 1.875 NM_207373
C10orf99
chromosome 10 open reading frame 99
chr1_+_26856240 1.869 NM_002953
RPS6KA1
ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr12_-_322612 1.860 NM_003044
NM_001122847
SLC6A12

solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 12

chr10_-_50396380 1.857 NM_001010863
C10orf128
chromosome 10 open reading frame 128
chr11_+_3666357 1.845 NM_004314
ART1
ADP-ribosyltransferase 1
chr19_-_6333561 1.834 NM_133492
ACER1
alkaline ceramidase 1
chr11_-_35441501 1.829 NM_001195728
NM_001252652
SLC1A2

solute carrier family 1 (glial high affinity glutamate transporter), member 2

chr1_-_160039946 1.810 NM_002241
KCNJ10
potassium inwardly-rectifying channel, subfamily J, member 10
chr16_+_29690464 1.808 QPRT
quinolinate phosphoribosyltransferase
chr16_+_71879893 1.798 NM_001137675
ATXN1L
ataxin 1-like
chr11_+_72980938 1.793 NM_176798
P2RY6
pyrimidinergic receptor P2Y, G-protein coupled, 6
chr1_+_26856252 1.788 RPS6KA1
ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr7_+_23286384 1.787 GPNMB
glycoprotein (transmembrane) nmb
chr7_+_23286420 1.777 GPNMB
glycoprotein (transmembrane) nmb
chr5_+_176875325 1.773 NM_001174102
PRR7
proline rich 7 (synaptic)
chr17_-_32483550 1.772 NM_001094
ACCN1
amiloride-sensitive cation channel 1, neuronal
chr2_+_121103670 1.739 NM_002193
INHBB
inhibin, beta B
chr7_+_23286390 1.733 GPNMB
glycoprotein (transmembrane) nmb
chr17_-_72588369 1.725 NM_001115152
CD300LD
CD300 molecule-like family member d
chr14_-_48144156 1.724 NM_001113498
MDGA2
MAM domain containing glycosylphosphatidylinositol anchor 2
chr19_-_42498320 1.715 NM_152296
ATP1A3
ATPase, Na+/K+ transporting, alpha 3 polypeptide
chr15_-_93198602 1.710 NM_207446
FAM174B
family with sequence similarity 174, member B
chr19_-_51504799 1.709 NM_007196
NM_144505
NM_144506
NM_144507
KLK8



kallikrein-related peptidase 8



chr16_-_3068161 1.706 NM_021195
CLDN6
claudin 6
chr2_+_16080559 1.696 MYCN
v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)
chr5_-_156772672 1.684 NM_001001343
FNDC9
fibronectin type III domain containing 9
chr19_+_19322763 1.681 NM_004386
NCAN
neurocan
chr13_+_37005966 1.677 NM_001111046
NM_001111047
CCNA1

cyclin A1

chr11_-_35441099 1.658 NM_004171
SLC1A2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr19_+_46800296 1.657 NM_152795
HIF3A
hypoxia inducible factor 3, alpha subunit
chr2_+_3642421 1.646 NM_024027
NM_199235
COLEC11

collectin sub-family member 11

chr7_+_150745604 1.641 NM_004769
NM_020321
NM_020322
ACCN3


amiloride-sensitive cation channel 3


chr2_-_109605616 1.634 EDAR
ectodysplasin A receptor
chr17_+_25799024 1.622 NM_014238
KSR1
kinase suppressor of ras 1
chr19_+_15751706 1.621 NM_000896
NM_001199208
NM_001199209
CYP4F3


cytochrome P450, family 4, subfamily F, polypeptide 3


chr15_-_73661141 1.617 HCN4
hyperpolarization activated cyclic nucleotide-gated potassium channel 4
chr20_-_23030141 1.603 NM_000361
THBD
thrombomodulin
chr21_-_31538970 1.603 NM_012131
CLDN17
claudin 17
chr11_-_10715160 1.602 MRVI1
murine retrovirus integration site 1 homolog
chr8_-_86789305 1.592 NM_172239
REXO1L1
REX1, RNA exonuclease 1 homolog (S. cerevisiae)-like 1
chr1_-_203154304 1.581 CHI3L1
chitinase 3-like 1 (cartilage glycoprotein-39)
chrX_-_118284541 1.580 NM_020721
KIAA1210
KIAA1210
chr8_+_48873533 1.577 MCM4
minichromosome maintenance complex component 4
chr11_-_35440514 1.576 SLC1A2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr8_-_98290171 1.574 NM_033512
TSPYL5
TSPY-like 5
chr1_+_26856259 1.547 RPS6KA1
ribosomal protein S6 kinase, 90kDa, polypeptide 1
chr19_-_42498221 1.543 ATP1A3
ATPase, Na+/K+ transporting, alpha 3 polypeptide
chr2_+_27371858 1.536 NM_175769
TCF23
transcription factor 23
chr19_-_10676689 1.521 NM_023008
KRI1
KRI1 homolog (S. cerevisiae)
chr3_+_124103551 1.510 KALRN
kalirin, RhoGEF kinase
chr2_-_193059249 1.496 TMEFF2
transmembrane protein with EGF-like and two follistatin-like domains 2
chr10_-_102890902 1.495 NM_001085398
TLX1NB
TLX1 neighbor
chr22_-_30162990 1.489


chr5_-_160112266 1.486 ATP10B
ATPase, class V, type 10B
chr10_+_102891060 1.479 NM_001195517
NM_005521
TLX1

T-cell leukemia homeobox 1

chr1_-_40105341 1.478 NM_014571
HEYL
hairy/enhancer-of-split related with YRPW motif-like
chr10_+_115511212 1.475 NM_001193434
NM_001193435
NM_024889
C10orf81


chromosome 10 open reading frame 81


chr1_-_153321021 1.474 NM_020393
PGLYRP4
peptidoglycan recognition protein 4
chr10_-_131762017 1.471 NM_001005463
EBF3
early B-cell factor 3
chr12_-_57328044 1.470 NM_148897
SDR9C7
short chain dehydrogenase/reductase family 9C, member 7
chr6_+_31082526 1.466 NM_014068
PSORS1C1
psoriasis susceptibility 1 candidate 1
chr3_-_170303774 1.464 NM_020949
SLC7A14
solute carrier family 7 (orphan transporter), member 14
chr5_-_131563481 1.460 NM_001017974
NM_001142598
NM_001142599
P4HA2


prolyl 4-hydroxylase, alpha polypeptide II


chr2_+_179059071 1.458 NM_001201480
NM_001201481
NM_001201482
NM_032523
OSBPL6



oxysterol binding protein-like 6



chr19_-_55549612 1.456 NM_001083899
NM_016363
GP6

glycoprotein VI (platelet)

chr19_-_10676646 1.455 KRI1
KRI1 homolog (S. cerevisiae)
chr8_-_145669796 1.452 NM_013432
TONSL
tonsoku-like, DNA repair protein
chr1_-_202130677 1.452 NM_001199797
NM_002832
PTPN7

protein tyrosine phosphatase, non-receptor type 7

chr12_-_43945723 1.451 NM_025003
ADAMTS20
ADAM metallopeptidase with thrombospondin type 1 motif, 20
chr2_-_39187477 1.449 LOC375196
uncharacterized LOC375196
chr1_-_27952591 1.445 NM_001042747
FGR
Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog
chr1_-_36235422 1.442 NM_001190481
NM_022111
CLSPN

claspin

chr12_+_113495661 1.431 NM_004416
DTX1
deltex homolog 1 (Drosophila)
chr17_+_38024416 1.419 NM_198844
NM_199321
ZPBP2

zona pellucida binding protein 2

chr4_+_7194317 1.416 NM_020777
SORCS2
sortilin-related VPS10 domain containing receptor 2
chr19_-_45926759 1.411 ERCC1
excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)
chr11_-_111250156 1.408 NM_006235
POU2AF1
POU class 2 associating factor 1
chr12_-_58159386 1.403 CYP27B1
cytochrome P450, family 27, subfamily B, polypeptide 1
chr6_-_90024936 1.402 NM_002043
GABRR2
gamma-aminobutyric acid (GABA) receptor, rho 2
chr19_-_19384022 1.397 NM_001001524
TM6SF2
transmembrane 6 superfamily member 2
chr4_-_40631846 1.396 NM_001098634
RBM47
RNA binding motif protein 47
chr1_+_151009028 1.389 NM_001159642
NM_138278
BNIPL

BCL2/adenovirus E1B 19kD interacting protein like

chr4_-_74864296 1.386 NM_002994
CXCL5
chemokine (C-X-C motif) ligand 5
chr2_-_100722328 1.384 AFF3
AF4/FMR2 family, member 3
chr11_-_111249902 1.379 POU2AF1
POU class 2 associating factor 1
chr12_+_112924284 1.371 PTPN11
protein tyrosine phosphatase, non-receptor type 11
chr1_-_40105296 1.370 HEYL
hairy/enhancer-of-split related with YRPW motif-like
chr5_+_175298538 1.367 CPLX2
complexin 2
chr7_-_126892304 1.365 NM_001127323
GRM8
glutamate receptor, metabotropic 8
chrX_-_112084006 1.360 NM_133265
AMOT
angiomotin
chrX_+_55246790 1.354 NM_130467
NM_001013435
PAGE5

P antigen family, member 5 (prostate associated)

chr19_-_45926819 1.349 NM_202001
ERCC1
excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)
chr10_-_6104113 1.348 NM_000417
IL2RA
interleukin 2 receptor, alpha
chr9_+_87283453 1.348 NM_001018064
NM_006180
NTRK2

neurotrophic tyrosine kinase, receptor, type 2

chr8_-_98290072 1.343 TSPYL5
TSPY-like 5
chr3_-_112013073 1.339 NM_183061
SLC9A10
solute carrier family 9, member 10
chr12_+_48592139 1.337 DKFZP779L1853
uncharacterized LOC643162
chr17_-_7493389 1.336 NM_006942
SOX15
SRY (sex determining region Y)-box 15
chr18_+_48086402 1.335 NM_002747
MAPK4
mitogen-activated protein kinase 4
chr5_+_75379238 1.326 NM_014979
SV2C
synaptic vesicle glycoprotein 2C
chr4_-_155533850 1.324 FGG
fibrinogen gamma chain
chr14_+_24521099 1.324 NM_138360
LRRC16B
leucine rich repeat containing 16B
chr16_+_23690234 1.323 PLK1
polo-like kinase 1
chr11_+_1860232 1.318 NM_003282
TNNI2
troponin I type 2 (skeletal, fast)
chr4_+_159690176 1.317 NM_020840
FNIP2
folliculin interacting protein 2
chr6_-_94129059 1.311 NM_004440
EPHA7
EPH receptor A7
chr4_-_72671236 1.308 NM_001204306
GC
group-specific component (vitamin D binding protein)
chr1_+_176432306 1.303 NM_020318
NM_021936
PAPPA2

pappalysin 2

chr17_+_7591666 1.296 NM_001143992
NM_018081
WRAP53

WD repeat containing, antisense to TP53

chr4_-_155412411 1.295 DCHS2
dachsous 2 (Drosophila)
chr20_-_45179212 1.288 NM_080721
C20orf123
chromosome 20 open reading frame 123
chr11_-_10715297 1.271 MRVI1
murine retrovirus integration site 1 homolog
chr6_+_54173202 1.270 NM_014464
TINAG
tubulointerstitial nephritis antigen
chr19_+_38085730 1.268 NM_001172225
NM_001172226
ZNF540

zinc finger protein 540

chr11_+_64126616 1.267 NM_001006944
NM_003942
RPS6KA4

ribosomal protein S6 kinase, 90kDa, polypeptide 4

chr16_+_71392615 1.263 NM_001740
NM_007088
CALB2

calbindin 2

chr19_+_50472856 1.258 SIGLEC16
sialic acid binding Ig-like lectin 16 (gene/pseudogene)
chr20_-_35201677 1.256


chr19_+_46806855 1.256 NM_152794
HIF3A
hypoxia inducible factor 3, alpha subunit
chr10_+_123872440 1.254 TACC2
transforming, acidic coiled-coil containing protein 2
chr15_+_59730272 1.252 NM_152450
FAM81A
family with sequence similarity 81, member A
chr19_-_45926631 1.251 ERCC1
excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)
chr1_-_182030749 1.249 NM_001009992
ZNF648
zinc finger protein 648
chr16_+_23690212 1.241 PLK1
polo-like kinase 1
chr8_-_23261632 1.241 LOXL2
lysyl oxidase-like 2
chr4_-_155533800 1.239 FGG
fibrinogen gamma chain
chr10_+_115939018 1.239 NM_198795
TDRD1
tudor domain containing 1
chr8_-_86575725 1.228 NM_172239
REXO1L1
REX1, RNA exonuclease 1 homolog (S. cerevisiae)-like 1
chrX_+_102470003 1.227 NM_001080425
NM_001127688
BEX4

brain expressed, X-linked 4

chr4_-_155533882 1.224 NM_000509
NM_021870
FGG

fibrinogen gamma chain

chr8_+_68864341 1.223 PREX2
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
chr21_+_27012067 1.218 JAM2
junctional adhesion molecule 2
chr13_-_38443859 1.217 NM_001135955
NM_001135956
NM_001135957
NM_001135958
NM_003306
NM_016179
TRPC4





transient receptor potential cation channel, subfamily C, member 4






Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
1.52 3.61e-03 GO:0032501 multicellular organismal process
2.69 1.65e-02 GO:0007155 cell adhesion
2.69 1.65e-02 GO:0022610 biological adhesion
41.80 2.29e-02 GO:0051938 L-glutamate import
1.62 3.37e-02 GO:0007275 multicellular organismal development
1.58 4.19e-02 GO:0032502 developmental process

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
2.05 5.39e-05 GO:0044459 plasma membrane part
1.46 2.63e-03 GO:0031224 intrinsic to membrane
1.55 4.92e-03 GO:0005886 plasma membrane
2.17 6.40e-03 GO:0005887 integral to plasma membrane
1.52 8.04e-03 GO:0071944 cell periphery
2.13 9.02e-03 GO:0031226 intrinsic to plasma membrane
31.35 1.22e-02 GO:0042555 MCM complex
1.41 2.44e-02 GO:0016021 integral to membrane
1.34 3.86e-02 GO:0044425 membrane part

Nothing significant found in function category.