Motif ID: HNF1A.p2

Z-value: 1.348


Transcription factors associated with HNF1A.p2:

Gene SymbolEntrez IDGene Name
HNF1A 6927 HNF1 homeobox A

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
HNF1Ahg19_v1_chr12_+_121416548_1214165690.253.3e-02Click!


Activity profile for motif HNF1A.p2.

activity profile for motif HNF1A.p2


Sorted Z-values histogram for motif HNF1A.p2

Sorted Z-values for motif HNF1A.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of HNF1A.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr10_+_101542460 9.686 NM_000392
ABCC2
ATP-binding cassette, sub-family C (CFTR/MRP), member 2
chr6_+_126070813 8.466 HEY2
hairy/enhancer-of-split related with YRPW motif 2
chr8_-_108510094 7.628 NM_001146
NM_001199859
ANGPT1

angiopoietin 1

chr10_+_101542554 7.331 ABCC2
ATP-binding cassette, sub-family C (CFTR/MRP), member 2
chr15_+_58430394 7.271 NM_020980
AQP9
aquaporin 9
chr10_+_99344421 7.257 HOGA1
4-hydroxy-2-oxoglutarate aldolase 1
chr6_+_126070724 6.733 NM_012259
HEY2
hairy/enhancer-of-split related with YRPW motif 2
chr1_+_18807423 6.673 NM_152375
KLHDC7A
kelch domain containing 7A
chr1_-_204183036 6.250 NM_198447
GOLT1A
golgi transport 1A
chr10_+_114154522 5.881 ACSL5
acyl-CoA synthetase long-chain family member 5
chr6_+_126070738 5.536 HEY2
hairy/enhancer-of-split related with YRPW motif 2
chr12_+_20963637 5.323 NM_019844
SLCO1B3
solute carrier organic anion transporter family, member 1B3
chr17_+_4692226 5.140 NM_001014985
GLTPD2
glycolipid transfer protein domain containing 2
chr10_+_85933553 4.628 NM_207373
C10orf99
chromosome 10 open reading frame 99
chr2_+_28718937 4.521 NM_001170585
NM_153021
PLB1

phospholipase B1

chr16_+_81272293 4.509 NM_017429
BCMO1
beta-carotene 15,15'-monooxygenase 1
chr2_+_234668914 4.312 NM_000463
UGT1A1
UDP glucuronosyltransferase 1 family, polypeptide A1
chr1_-_197036350 4.172 NM_001994
F13B
coagulation factor XIII, B polypeptide
chr19_+_11350282 4.153 NM_018687
C19orf80
chromosome 19 open reading frame 80
chr13_+_53602829 3.952 NM_006418
OLFM4
olfactomedin 4
chr15_+_62939509 3.859 NM_015059
TLN2
talin 2
chr4_-_69434215 3.792 NM_001077
UGT2B15
UGT2B17
UDP glucuronosyltransferase 2 family, polypeptide B15
UDP glucuronosyltransferase 2 family, polypeptide B17
chr1_+_48688356 3.765 NM_001011547
NM_001135181
SLC5A9

solute carrier family 5 (sodium/glucose cotransporter), member 9

chr20_+_42984338 3.752 NM_001030003
NM_001030004
NM_175914
HNF4A


hepatocyte nuclear factor 4, alpha


chr5_+_76435073 3.746


chr17_+_73642645 3.744 NM_001162997
C17orf110
chromosome 17 open reading frame 110
chr10_+_5136589 3.690 AKR1C3
aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
chr17_-_202557 3.664 RPH3AL
rabphilin 3A-like (without C2 domains)
chr6_-_30899926 3.644 NM_205854
SFTA2
surfactant associated 2
chr12_-_53601051 3.554 ITGB7
integrin, beta 7
chr10_+_5136613 3.550 AKR1C3
aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
chr6_-_24383519 3.497 NM_001195610
DCDC2
doublecortin domain containing 2
chr14_+_68168602 3.373 NM_152443
RDH12
retinol dehydrogenase 12 (all-trans/9-cis/11-cis)
chr10_+_135340865 3.370 NM_000773
CYP2E1
cytochrome P450, family 2, subfamily E, polypeptide 1
chr1_-_198906536 3.198 LOC100131234
familial acute myelogenous leukemia related factor
chr2_+_234526290 3.161 NM_019076
UGT1A8
UDP glucuronosyltransferase 1 family, polypeptide A8
chr10_+_5136556 3.150 NM_003739
AKR1C3
aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
chr20_+_43029936 3.124 HNF4A
hepatocyte nuclear factor 4, alpha
chr7_-_47579192 3.113 TNS3
tensin 3
chr5_+_175976342 3.091 NM_017675
CDHR2
cadherin-related family member 2
chr8_-_124749573 3.085 NM_001003954
NM_004306
ANXA13

annexin A13

chr2_+_234627423 3.062 NM_007120
UGT1A4
UDP glucuronosyltransferase 1 family, polypeptide A4
chr7_-_104567089 3.011 LOC723809
uncharacterized LOC723809
chr8_+_76320106 2.981 HNF4G
hepatocyte nuclear factor 4, gamma
chr14_+_39703119 2.977 NM_054024
MIA2
melanoma inhibitory activity 2
chr16_+_89696674 2.951 DPEP1
dipeptidase 1 (renal)
chr14_-_94759360 2.928 NM_016186
SERPINA10
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
chr4_+_3443691 2.912 NM_001528
HGFAC
HGF activator
chr10_+_99344079 2.905 NM_001134670
NM_138413
HOGA1

4-hydroxy-2-oxoglutarate aldolase 1

chr6_-_32557431 2.841 NM_001243965
NM_002124
HLA-DRB1

HLA-DRB4
HLA-DRB5
major histocompatibility complex, class II, DR beta 1

major histocompatibility complex, class II, DR beta 4
major histocompatibility complex, class II, DR beta 5
chr16_-_55909208 2.820 NM_001143685
NM_145024
CES5A

carboxylesterase 5A

chr14_-_94759556 2.801 SERPINA10
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
chr2_+_152214105 2.787 NM_007115
TNFAIP6
tumor necrosis factor, alpha-induced protein 6
chr5_+_1225469 2.771 NM_182632
SLC6A18
solute carrier family 6, member 18
chr12_-_53600999 2.739 NM_000889
ITGB7
integrin, beta 7
chr20_+_43030005 2.726 HNF4A
hepatocyte nuclear factor 4, alpha
chr12_+_21284127 2.719 NM_006446
SLCO1B1
solute carrier organic anion transporter family, member 1B1
chr4_+_3443659 2.652 HGFAC
HGF activator
chr14_-_94759594 2.630 NM_001100607
SERPINA10
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
chr8_-_95220769 2.618 NM_004063
CDH17
cadherin 17, LI cadherin (liver-intestine)
chr9_-_94712079 2.606 NM_004560
ROR2
receptor tyrosine kinase-like orphan receptor 2
chr15_+_58724174 2.558 NM_000236
LIPC
lipase, hepatic
chr20_+_42984088 2.549 HNF4A
hepatocyte nuclear factor 4, alpha
chr16_+_89696775 2.514 DPEP1
dipeptidase 1 (renal)
chr7_-_44580857 2.509 NM_001101648
NM_013389
NPC1L1

NPC1 (Niemann-Pick disease, type C1, gene)-like 1

chr11_-_117695408 2.473 NM_001680
FXYD2
FXYD domain containing ion transport regulator 2
chr9_+_82186846 2.459 NM_007005
TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr4_-_189026401 2.441 NM_173553
TRIML2
tripartite motif family-like 2
chr3_-_169587598 2.427 NM_024727
LRRC31
leucine rich repeat containing 31
chr2_-_99917638 2.416 NM_174898
LYG1
lysozyme G-like 1
chr12_+_10331556 2.401 NM_153022
C12orf59
chromosome 12 open reading frame 59
chr5_-_138718941 2.387 SLC23A1
solute carrier family 23 (nucleobase transporters), member 1
chr13_+_51915167 2.379 NM_001101320
SERPINE3
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 3
chr22_+_32439211 2.366 SLC5A1
solute carrier family 5 (sodium/glucose cotransporter), member 1
chr14_-_57960432 2.362 NM_018168
C14orf105
chromosome 14 open reading frame 105
chrX_+_70435048 2.312 NM_001097642
GJB1
gap junction protein, beta 1, 32kDa
chrX_+_70435087 2.309 GJB1
gap junction protein, beta 1, 32kDa
chr11_+_64323089 2.282 NM_018484
SLC22A11
solute carrier family 22 (organic anion/urate transporter), member 11
chr2_+_234601511 2.282 NM_001072
UGT1A6
UDP glucuronosyltransferase 1 family, polypeptide A6
chr17_-_202617 2.266 NM_001190411
NM_001190412
NM_001190413
NM_006987
RPH3AL



rabphilin 3A-like (without C2 domains)



chr20_+_43029865 2.265 NM_000457
NM_178849
NM_178850
HNF4A


hepatocyte nuclear factor 4, alpha


chr7_-_50633042 2.250 NM_001082971
DDC
dopa decarboxylase (aromatic L-amino acid decarboxylase)
chr20_+_43029973 2.237 HNF4A
hepatocyte nuclear factor 4, alpha
chr4_+_169013687 2.227 NM_007193
ANXA10
annexin A10
chr1_-_103496768 2.216 COL11A1
collagen, type XI, alpha 1
chr1_-_159684274 2.175 NM_000567
CRP
C-reactive protein, pentraxin-related
chr17_-_64225496 2.146 NM_000042
APOH
apolipoprotein H (beta-2-glycoprotein I)
chr4_-_155511838 2.134 NM_000508
NM_021871
FGA

fibrinogen alpha chain

chr20_+_42187634 2.129 NM_170693
SGK2
serum/glucocorticoid regulated kinase 2
chr5_-_147211141 2.108 SPINK1
serine peptidase inhibitor, Kazal type 1
chr1_-_206288646 2.098 NM_001007544
C1orf186
chromosome 1 open reading frame 186
chr21_-_19775958 2.091 NM_002772
TMPRSS15
transmembrane protease, serine 15
chr22_+_32439103 2.088 SLC5A1
solute carrier family 5 (sodium/glucose cotransporter), member 1
chr7_+_120629444 2.074 NM_001105533
C7orf58
chromosome 7 open reading frame 58
chr4_+_74301932 2.070 NM_001134
AFP
alpha-fetoprotein
chr1_-_42630386 2.059 NM_033553
GUCA2A
guanylate cyclase activator 2A (guanylin)
chr12_-_22487566 2.041 NM_003034
ST8SIA1
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
chr14_-_94789641 2.025 NM_001756
SERPINA6
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6
chr7_+_45927958 2.020 NM_000596
IGFBP1
insulin-like growth factor binding protein 1
chr22_+_32439250 1.980 SLC5A1
solute carrier family 5 (sodium/glucose cotransporter), member 1
chr11_+_46740736 1.975 NM_000506
F2
coagulation factor II (thrombin)
chr1_-_114430168 1.964 NM_001010922
BCL2L15
BCL2-like 15
chr4_-_122148620 1.951 NM_001244764
TNIP3
TNFAIP3 interacting protein 3
chr15_+_59903980 1.946 NM_004751
GCNT3
glucosaminyl (N-acetyl) transferase 3, mucin type
chr2_-_228244005 1.946 NM_024795
TM4SF20
transmembrane 4 L six family member 20
chr1_+_43253660 1.943 NM_001242750
LOC100129924
uncharacterized LOC100129924
chr6_+_30973728 1.929 NM_001198815
MUC22
mucin 22
chr11_+_46740769 1.928 F2
coagulation factor II (thrombin)
chr4_+_155484131 1.905 NM_001184741
NM_005141
FGB

fibrinogen beta chain

chr6_-_116381765 1.894 NM_002031
FRK
fyn-related kinase
chr11_-_64825992 1.890 NM_005468
NAALADL1
N-acetylated alpha-linked acidic dipeptidase-like 1
chr22_+_32439018 1.882 NM_000343
SLC5A1
solute carrier family 5 (sodium/glucose cotransporter), member 1
chr14_-_64749530 1.878 NM_001214902
NM_001214903
ESR2

estrogen receptor 2 (ER beta)

chr5_-_147211235 1.838 NM_003122
SPINK1
serine peptidase inhibitor, Kazal type 1
chr17_+_41052813 1.835 NM_000151
G6PC
glucose-6-phosphatase, catalytic subunit
chr2_+_29038862 1.800 NM_001008779
SPDYA
speedy homolog A (Xenopus laevis)
chr10_-_106098161 1.792 ITPRIP
inositol 1,4,5-trisphosphate receptor interacting protein
chr2_-_1946873 1.786 MYT1L
myelin transcription factor 1-like
chr4_+_187187117 1.778 NM_000128
F11
coagulation factor XI
chr6_+_54173202 1.727 NM_014464
TINAG
tubulointerstitial nephritis antigen
chr14_+_78870092 1.714 NM_004796
NRXN3
neurexin 3
chr10_+_64280206 1.713 NM_199452
ZNF365
zinc finger protein 365
chr12_+_56624500 1.702 NM_001135195
SLC39A5
solute carrier family 39 (metal ion transporter), member 5
chr1_-_67266930 1.701 NM_005478
INSL5
insulin-like 5
chr19_-_48389514 1.673 SULT2A1
sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1
chrX_+_2958274 1.656 NM_001201538
ARSF
arylsulfatase F
chr1_+_119911395 1.655 NM_001005783
NM_016527
HAO2

hydroxyacid oxidase 2 (long chain)

chr2_+_234637772 1.653 NM_019093
UGT1A3
UDP glucuronosyltransferase 1 family, polypeptide A3
chr6_-_32497925 1.647 NM_002125
HLA-DRB5
major histocompatibility complex, class II, DR beta 5
chr10_-_52645384 1.633 A1CF
APOBEC1 complementation factor
chr10_-_52645430 1.629 NM_001198818
NM_001198819
NM_001198820
NM_014576
NM_138932
NM_138933
A1CF





APOBEC1 complementation factor





chr3_+_183948216 1.625 NM_138345
VWA5B2
von Willebrand factor A domain containing 5B2
chr16_+_76343734 1.616 NM_138994
CNTNAP4
contactin associated protein-like 4
chr5_-_138719018 1.608 NM_005847
NM_152685
SLC23A1

solute carrier family 23 (nucleobase transporters), member 1

chr7_-_115608366 1.584 NM_001244583
TFEC
transcription factor EC
chr7_-_107443631 1.580 NM_000111
SLC26A3
solute carrier family 26, member 3
chr1_+_159557615 1.573 NM_001639
APCS
amyloid P component, serum
chr1_-_114429996 1.568 BCL2L15
BCL2-like 15
chr5_-_160112266 1.562 ATP10B
ATPase, class V, type 10B
chr20_-_7921068 1.545 NM_017545
HAO1
hydroxyacid oxidase (glycolate oxidase) 1
chr4_+_25658085 1.497 NM_001177999
SLC34A2
solute carrier family 34 (sodium phosphate), member 2
chr16_-_66952729 1.492 NM_001204744
NM_001204745
NM_001204746
NM_004062
CDH16



cadherin 16, KSP-cadherin



chr16_+_31404596 1.485 NM_005353
ITGAD
integrin, alpha D
chr19_-_48389571 1.483 NM_003167
SULT2A1
sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1
chr20_+_42187705 1.483 SGK2
serum/glucocorticoid regulated kinase 2
chr6_+_161123224 1.468 NM_000301
NM_001168338
PLG

plasminogen

chr19_+_15052298 1.460 NM_012377
OR7C2
olfactory receptor, family 7, subfamily C, member 2
chrX_+_36254050 1.446 NM_001098843
CXorf30
chromosome X open reading frame 30
chr6_-_51952368 1.422 NM_138694
NM_170724
PKHD1

polycystic kidney and hepatic disease 1 (autosomal recessive)

chr6_+_167536240 1.421 NM_031409
CCR6
chemokine (C-C motif) receptor 6
chr2_-_102003923 1.417 NM_153836
CREG2
cellular repressor of E1A-stimulated genes 2
chr5_-_135290521 1.413 NM_002302
LECT2
leukocyte cell-derived chemotaxin 2
chr3_-_157221127 1.410 NM_001167911
NM_001167912
VEPH1

ventricular zone expressed PH domain homolog 1 (zebrafish)

chr12_-_18243052 1.406 NM_024730
RERGL
RERG/RAS-like
chr2_-_162931051 1.384 NM_001935
DPP4
dipeptidyl-peptidase 4
chr1_+_15764934 1.374 NM_007272
CTRC
chymotrypsin C (caldecrin)
chr3_+_160394946 1.361 NM_025047
ARL14
ADP-ribosylation factor-like 14
chr7_+_55980330 1.335 NM_182633
ZNF713
zinc finger protein 713
chr4_+_74269971 1.329 NM_000477
ALB
albumin
chr6_-_119470336 1.323 NM_001100411
FAM184A
family with sequence similarity 184, member A
chr4_-_159093523 1.314 FAM198B
family with sequence similarity 198, member B
chr9_-_71155729 1.313 NM_153237
C9orf71
chromosome 9 open reading frame 71
chr12_-_22089627 1.312 NM_005691
NM_020297
ABCC9

ATP-binding cassette, sub-family C (CFTR/MRP), member 9

chr13_-_99959649 1.286 NM_004951
GPR183
G protein-coupled receptor 183
chr17_-_66951381 1.286 NM_007168
ABCA8
ATP-binding cassette, sub-family A (ABC1), member 8
chr2_+_234580504 1.285 NM_021027
UGT1A9
UDP glucuronosyltransferase 1 family, polypeptide A9
chr2_+_234621637 1.253 NM_019078
UGT1A5
UDP glucuronosyltransferase 1 family, polypeptide A5
chr6_-_137494719 1.251 NM_052962
NM_181309
NM_181310
IL22RA2


interleukin 22 receptor, alpha 2


chr17_+_35732927 1.227 NM_173625
C17orf78
chromosome 17 open reading frame 78
chrX_+_36065052 1.224 NM_173695
CXorf59
chromosome X open reading frame 59
chr3_-_141719188 1.209 NM_001178140
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr19_-_33360641 1.200 NM_001126335
NM_001243036
NM_014270
SLC7A9


solute carrier family 7 (glycoprotein-associated amino acid transporter light chain, bo,+ system), member 9


chr9_-_27573444 1.197 NM_018325
C9orf72
chromosome 9 open reading frame 72
chr16_+_21245015 1.193 NM_145865
ANKS4B
ankyrin repeat and sterile alpha motif domain containing 4B
chr4_-_100212085 1.193 NM_000667
ADH1A
alcohol dehydrogenase 1A (class I), alpha polypeptide
chr20_+_32250089 1.190 NM_080825
C20orf144
chromosome 20 open reading frame 144
chr3_+_119316694 1.180 NM_001206960
NM_001206961
NM_015900
PLA1A


phospholipase A1 member A


chr5_-_139726173 1.169 NM_001945
HBEGF
heparin-binding EGF-like growth factor
chr12_-_102874373 1.158 NM_000618
NM_001111283
NM_001111285
IGF1


insulin-like growth factor 1 (somatomedin C)


chr1_+_109255555 1.104 NM_001144937
FNDC7
fibronectin type III domain containing 7
chr2_-_162930544 1.103 DPP4
dipeptidyl-peptidase 4
chr7_+_139528951 1.101 NM_001061
NM_001166253
NM_030984
TBXAS1


thromboxane A synthase 1 (platelet)


chr16_-_48269087 1.015 NM_032583
NM_145186
ABCC11

ATP-binding cassette, sub-family C (CFTR/MRP), member 11

chr7_-_5461517 0.993 TNRC18
trinucleotide repeat containing 18
chr11_+_119056165 0.975 NM_001168468
NM_024791
PDZD3

PDZ domain containing 3

chrX_-_15332680 0.954 NM_001012428
ASB11
ankyrin repeat and SOCS box containing 11
chr11_-_101787252 0.946 NM_178127
ANGPTL5
angiopoietin-like 5
chr18_-_48346297 0.930 NM_001127175
NM_001127176
NM_031939
MRO


maestro


chr13_-_101185944 0.910 NM_033110
A2LD1
AIG2-like domain 1
chr12_-_24102563 0.909 NM_006940
SOX5
SRY (sex determining region Y)-box 5
chr17_-_39216343 0.899 NM_001165252
LOC730755
keratin associated protein 2-4-like
chr12_+_25205488 0.891 LRMP
lymphoid-restricted membrane protein
chr12_-_102874299 0.888 IGF1
insulin-like growth factor 1 (somatomedin C)
chr3_-_150966901 0.881 NM_001081455
P2RY14
purinergic receptor P2Y, G-protein coupled, 14
chr20_+_62371218 0.874 SLC2A4RG
SLC2A4 regulator
chr12_+_20724797 0.865 NM_001244683
PDE3A
phosphodiesterase 3A, cGMP-inhibited
chr12_-_102874340 0.862 IGF1
insulin-like growth factor 1 (somatomedin C)
chr6_+_167704802 0.861 NM_001143947
NM_018974
UNC93A

unc-93 homolog A (C. elegans)

chr11_-_121986800 0.847 NM_001001786
BLID
BH3-like motif containing, cell death inducer
chr4_-_72649734 0.846 NM_000583
GC
group-specific component (vitamin D binding protein)

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
8.95 1.71e-08 GO:0008202 steroid metabolic process
11.97 3.55e-08 GO:0006805 xenobiotic metabolic process
11.97 3.55e-08 GO:0071466 cellular response to xenobiotic stimulus
11.88 3.91e-08 GO:0009410 response to xenobiotic stimulus
23.88 6.95e-07 GO:0006721 terpenoid metabolic process
3.84 7.55e-07 GO:0006629 lipid metabolic process
25.96 4.21e-06 GO:0001523 retinoid metabolic process
25.96 4.21e-06 GO:0016101 diterpenoid metabolic process
6.25 1.02e-05 GO:0032787 monocarboxylic acid metabolic process
16.06 1.87e-05 GO:0006720 isoprenoid metabolic process
15.07 3.11e-05 GO:0019748 secondary metabolic process
3.82 1.50e-04 GO:0006082 organic acid metabolic process
3.89 2.35e-04 GO:0044255 cellular lipid metabolic process
54.39 2.94e-04 GO:0009812 flavonoid metabolic process
44.51 7.60e-04 GO:0009698 phenylpropanoid metabolic process
40.80 1.13e-03 GO:0051917 regulation of fibrinolysis
11.43 1.47e-03 GO:0034754 cellular hormone metabolic process
7.71 1.49e-03 GO:0042445 hormone metabolic process
21.86 1.61e-03 GO:0006776 vitamin A metabolic process
6.55 1.78e-03 GO:0010817 regulation of hormone levels
3.52 2.00e-03 GO:0019752 carboxylic acid metabolic process
3.52 2.00e-03 GO:0043436 oxoacid metabolic process
3.44 2.72e-03 GO:0042180 cellular ketone metabolic process
73.43 2.98e-03 GO:0051552 flavone metabolic process
28.80 5.28e-03 GO:0042573 retinoic acid metabolic process
2.16 5.93e-03 GO:0065008 regulation of biological quality
14.58 1.27e-02 GO:0006775 fat-soluble vitamin metabolic process
3.44 1.81e-02 GO:0042060 wound healing
20.40 2.25e-02 GO:0017144 drug metabolic process
40.80 2.44e-02 GO:0051918 negative regulation of fibrinolysis
12.75 2.47e-02 GO:0061041 regulation of wound healing
8.96 3.17e-02 GO:0031099 regeneration
122.38 3.74e-02 GO:0009441 glycolate metabolic process
17.49 4.23e-02 GO:0030195 negative regulation of blood coagulation
16.89 4.88e-02 GO:0050819 negative regulation of coagulation

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
8.75 1.54e-06 GO:0016324 apical plasma membrane
2.44 1.34e-05 GO:0005576 extracellular region
6.97 1.92e-05 GO:0045177 apical part of cell
6.28 5.85e-05 GO:0005792 microsome
6.08 8.36e-05 GO:0042598 vesicular fraction
3.29 3.20e-04 GO:0005615 extracellular space
2.79 1.41e-03 GO:0044421 extracellular region part
13.03 4.69e-03 GO:0031093 platelet alpha granule lumen
12.75 5.20e-03 GO:0034774 secretory granule lumen
12.24 6.35e-03 GO:0060205 cytoplasmic membrane-bounded vesicle lumen
3.10 7.27e-03 GO:0005789 endoplasmic reticulum membrane
11.77 7.68e-03 GO:0031983 vesicle lumen
2.92 8.52e-03 GO:0044432 endoplasmic reticulum part
1.99 9.31e-03 GO:0044459 plasma membrane part
3.02 9.57e-03 GO:0042175 nuclear membrane-endoplasmic reticulum network
10.74 1.20e-02 GO:0031091 platelet alpha granule
2.73 1.99e-02 GO:0005624 membrane fraction
2.41 2.73e-02 GO:0005783 endoplasmic reticulum
2.64 2.91e-02 GO:0005626 insoluble fraction
2.37 3.43e-02 GO:0000267 cell fraction

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
39.34 1.42e-10 GO:0015020 glucuronosyltransferase activity
10.38 8.28e-06 GO:0008194 UDP-glycosyltransferase activity
19.48 1.17e-05 GO:0043498 cell surface binding
5.41 2.32e-05 GO:0022804 active transmembrane transporter activity
44.51 2.54e-04 GO:0001972 retinoic acid binding
7.12 2.80e-04 GO:0016758 transferase activity, transferring hexosyl groups
5.52 9.86e-04 GO:0016757 transferase activity, transferring glycosyl groups
32.64 1.03e-03 GO:0008514 organic anion transmembrane transporter activity
13.12 1.17e-03 GO:0033293 monocarboxylic acid binding
28.80 1.77e-03 GO:0043499 eukaryotic cell surface binding
22.26 5.26e-03 GO:0005501 retinoid binding
21.29 6.32e-03 GO:0019840 isoprenoid binding
3.82 7.14e-03 GO:0008289 lipid binding
122.38 1.25e-02 GO:0003973 (S)-2-hydroxy-acid oxidase activity
122.38 1.25e-02 GO:0016899 oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor
33.38 1.59e-02 GO:0010181 FMN binding
7.42 3.03e-02 GO:0042626 ATPase activity, coupled to transmembrane movement of substances
7.35 3.20e-02 GO:0016820 hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
7.35 3.20e-02 GO:0043492 ATPase activity, coupled to movement of substances
5.96 3.41e-02 GO:0004252 serine-type endopeptidase activity
9.42 3.56e-02 GO:0005496 steroid binding
81.59 3.74e-02 GO:0005412 glucose:sodium symporter activity
4.98 4.08e-02 GO:0015291 secondary active transmembrane transporter activity
5.76 4.21e-02 GO:0031406 carboxylic acid binding