Motif ID: GFI1.p2

Z-value: 1.715


Transcription factors associated with GFI1.p2:

Gene SymbolEntrez IDGene Name
GFI1 2672 growth factor independent 1 transcription repressor

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
GFI1hg19_v1_chr1_-_92949355_92949404-0.225.3e-02Click!


Activity profile for motif GFI1.p2.

activity profile for motif GFI1.p2


Sorted Z-values histogram for motif GFI1.p2

Sorted Z-values for motif GFI1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of GFI1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_-_24645084 11.692 NM_006727
CDH10
cadherin 10, type 2 (T2-cadherin)
chr12_-_49259549 11.202 NM_014470
RND1
Rho family GTPase 1
chr6_+_26225382 10.703 NM_003532
HIST1H3E
histone cluster 1, H3e
chrX_+_102631408 10.422 NGFRAP1
nerve growth factor receptor (TNFRSF16) associated protein 1
chr17_-_47841517 10.020 NM_030802
FAM117A
family with sequence similarity 117, member A
chr16_+_82660573 10.012 CDH13
cadherin 13, H-cadherin (heart)
chr8_-_124544376 10.003 NM_148177
FBXO32
F-box protein 32
chr19_-_14247267 9.856 ASF1B
ASF1 anti-silencing function 1 homolog B (S. cerevisiae)
chr16_+_82660390 9.489 NM_001220488
NM_001220489
NM_001220490
NM_001220491
NM_001220492
NM_001257
CDH13





cadherin 13, H-cadherin (heart)





chrX_+_102631267 9.358 NM_206915
NM_206917
NGFRAP1

nerve growth factor receptor (TNFRSF16) associated protein 1

chr1_+_164528586 8.978 NM_001204961
NM_001204963
NM_002585
PBX1


pre-B-cell leukemia homeobox 1


chr1_+_164528914 8.960 PBX1
pre-B-cell leukemia homeobox 1
chr19_-_14247400 8.904 NM_018154
ASF1B
ASF1 anti-silencing function 1 homolog B (S. cerevisiae)
chr17_-_47841468 8.801 FAM117A
family with sequence similarity 117, member A
chr4_-_186733372 8.346 NM_003603
NM_001145670
SORBS2

sorbin and SH3 domain containing 2

chr5_-_124080773 7.908 NM_020747
ZNF608
zinc finger protein 608
chr20_+_44746948 7.755 CD40
CD40 molecule, TNF receptor superfamily member 5
chr19_-_35981345 7.723 NM_001244847
NM_207392
KRTDAP

keratinocyte differentiation-associated protein

chr20_+_44746889 7.289 NM_001250
NM_152854
CD40

CD40 molecule, TNF receptor superfamily member 5

chr11_+_118401873 7.252 TMEM25
transmembrane protein 25
chrX_+_84498993 7.067 NM_021998
ZNF711
zinc finger protein 711
chr4_-_174255454 7.034 NM_001130688
NM_002129
HMGB2

high mobility group box 2

chr12_-_120315074 6.996 NM_001206999
NM_007174
CIT

citron (rho-interacting, serine/threonine kinase 21)

chr17_-_48072566 6.964 NM_005220
DLX3
distal-less homeobox 3
chr19_-_12251092 6.826 NM_001203250
NM_021143
ZNF20

zinc finger protein 20

chr2_-_45236521 6.740 NM_016932
SIX2
SIX homeobox 2
chr14_+_53019865 6.719 NM_001099652
GPR137C
G protein-coupled receptor 137C
chr13_+_43148182 6.704 NM_003701
TNFSF11
tumor necrosis factor (ligand) superfamily, member 11
chr1_+_201979689 6.492 NM_001114309
NM_004433
ELF3

E74-like factor 3 (ets domain transcription factor, epithelial-specific )

chr12_+_6603291 6.051 NM_014865
NCAPD2
non-SMC condensin I complex, subunit D2
chr12_+_6603258 5.701 NCAPD2
non-SMC condensin I complex, subunit D2
chr7_-_139168408 5.627 NM_198508
KLRG2
killer cell lectin-like receptor subfamily G, member 2
chr6_+_26045611 5.595 NM_003531
HIST1H3C
histone cluster 1, H3c
chr3_-_48632592 5.536 NM_000094
COL7A1
collagen, type VII, alpha 1
chr17_-_38574042 5.534 NM_001067
TOP2A
topoisomerase (DNA) II alpha 170kDa
chr1_+_149824180 5.505 NM_021059
NM_001005464
HIST2H3C
HIST2H3A
histone cluster 2, H3c
histone cluster 2, H3a
chr6_+_31430955 5.372 HCP5
HLA complex P5 (non-protein coding)
chr2_-_160761266 5.367 NM_001198759
NM_001198760
NM_002349
LY75-CD302

LY75
LY75-CD302 readthrough

lymphocyte antigen 75
chr19_+_45971249 5.281 NM_001114171
NM_006732
FOSB

FBJ murine osteosarcoma viral oncogene homolog B

chr2_-_157189040 5.264 NM_006186
NR4A2
nuclear receptor subfamily 4, group A, member 2
chr14_-_91526912 5.192 NM_004755
NM_182398
RPS6KA5

ribosomal protein S6 kinase, 90kDa, polypeptide 5

chr9_-_73028278 5.181 KLF9
Kruppel-like factor 9
chr17_+_57408907 5.169 NM_001005404
YPEL2
yippee-like 2 (Drosophila)
chr16_-_54320328 5.087 IRX3
iroquois homeobox 3
chr12_-_122240827 5.039


chr6_-_134498973 5.014 NM_001143677
SGK1
serum/glucocorticoid regulated kinase 1
chr2_-_160761192 4.962 LY75-CD302
LY75
LY75-CD302 readthrough
lymphocyte antigen 75
chr1_-_46598250 4.950 NM_003629
NM_001114172
PIK3R3

phosphoinositide-3-kinase, regulatory subunit 3 (gamma)

chr14_+_58765275 4.865 ARID4A
AT rich interactive domain 4A (RBP1-like)
chr16_-_79634610 4.861 NM_001031804
NM_005360
MAF

v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian)

chr1_-_149812733 4.801 NM_021059
NM_001005464
HIST2H3C
HIST2H3A
histone cluster 2, H3c
histone cluster 2, H3a
chr17_+_16284408 4.729 UBB
ubiquitin B
chr4_+_166794409 4.693 NM_001204760
NM_012464
TLL1

tolloid-like 1

chr1_+_201979747 4.643 ELF3
E74-like factor 3 (ets domain transcription factor, epithelial-specific )
chr19_-_12146503 4.634 NM_001080411
ZNF433
zinc finger protein 433
chr17_+_16284350 4.627 NM_018955
UBB
ubiquitin B
chr3_-_64211111 4.545 NM_198859
PRICKLE2
prickle homolog 2 (Drosophila)
chrX_+_84499037 4.493 ZNF711
zinc finger protein 711
chr7_+_156803599 4.481 LOC645249
uncharacterized LOC645249
chr9_-_99801365 4.459 NM_001333
CTSL2
cathepsin L2
chr17_+_16284401 4.459 UBB
ubiquitin B
chr1_+_151763174 4.449


chr2_+_183943511 4.427 DUSP19
dual specificity phosphatase 19
chr7_+_100183926 4.404 NM_033506
FBXO24
F-box protein 24
chr2_+_183943468 4.387 DUSP19
dual specificity phosphatase 19
chr11_+_118401755 4.362 NM_001144034
NM_001144035
NM_001144036
NM_001144037
NM_001144038
NM_032780
TMEM25





transmembrane protein 25





chr17_+_61699786 4.247 NM_002401
NM_203351
MAP3K3

mitogen-activated protein kinase kinase kinase 3

chr14_-_55658205 4.244 NM_001146015
NM_014750
DLGAP5

discs, large (Drosophila) homolog-associated protein 5

chr2_+_183943286 4.228 NM_001142314
NM_080876
DUSP19

dual specificity phosphatase 19

chr6_-_27775683 4.193 NM_003519
HIST1H2BL
histone cluster 1, H2bl
chr14_+_58765209 4.193 NM_002892
NM_023000
NM_023001
ARID4A


AT rich interactive domain 4A (RBP1-like)


chr6_-_26199439 4.172 NM_021065
NM_003530
HIST1H2AD
HIST1H3D
histone cluster 1, H2ad
histone cluster 1, H3d
chr8_-_95961543 4.153 NM_001135733
NM_033285
TP53INP1

tumor protein p53 inducible nuclear protein 1

chr6_+_33359604 4.065 KIFC1
kinesin family member C1
chr6_+_33359574 4.052 KIFC1
kinesin family member C1
chr12_+_54447660 4.038 NM_153633
HOXC4
HOXC6
homeobox C4
homeobox C6
chr16_+_30907927 4.019 NM_001142544
NM_001330
CTF1

cardiotrophin 1

chr5_+_172483285 3.976 NM_001168393
NM_001168394
NM_153607
C5orf41


chromosome 5 open reading frame 41


chr6_+_33359620 3.957 KIFC1
kinesin family member C1
chr4_-_82393025 3.955 NM_152545
RASGEF1B
RasGEF domain family, member 1B
chr8_+_25316512 3.943 NM_152562
CDCA2
cell division cycle associated 2
chr17_+_61699715 3.932 MAP3K3
mitogen-activated protein kinase kinase kinase 3
chr6_+_33359624 3.930 KIFC1
kinesin family member C1
chr2_+_65216526 3.927 SLC1A4
solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
chr12_+_49716970 3.920 NM_001100620
NM_005480
TROAP

trophinin associated protein (tastin)

chr10_-_72142344 3.910 NM_018205
NM_018239
LRRC20

leucine rich repeat containing 20

chr17_+_61699783 3.902 MAP3K3
mitogen-activated protein kinase kinase kinase 3
chr10_+_76586299 3.894 NM_012330
KAT6B
K(lysine) acetyltransferase 6B
chr17_+_57233100 3.880 PRR11
proline rich 11
chr6_-_26216871 3.865 NM_003518
HIST1H2BG
NCALD
histone cluster 1, H2bg
neurocalcin delta
chr9_-_23826062 3.863 NM_004432
ELAVL2
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr19_+_12273866 3.851 NM_003437
ZNF136
zinc finger protein 136
chr4_-_186877413 3.847 SORBS2
sorbin and SH3 domain containing 2
chr14_-_58618807 3.837 NM_001001872
C14orf37
chromosome 14 open reading frame 37
chr1_+_214776494 3.835 NM_016343
CENPF
centromere protein F, 350/400kDa (mitosin)
chr19_-_12444435 3.800 NM_145276
ZNF563
zinc finger protein 563
chr9_-_73029539 3.770 NM_001206
KLF9
Kruppel-like factor 9
chr14_+_95623991 3.755 DICER1-AS
DICER1 antisense RNA (non-protein coding)
chr6_-_26197477 3.753 HIST1H3D
histone cluster 1, H3d
chr1_+_214776582 3.748 CENPF
centromere protein F, 350/400kDa (mitosin)
chr6_+_46097700 3.747 NM_014936
ENPP4
ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative)
chr11_-_94964209 3.713 NM_144665
SESN3
sestrin 3
chr19_-_12146485 3.710 ZNF433
zinc finger protein 433
chr9_-_99801924 3.710 NM_001201575
CTSL2
cathepsin L2
chr19_+_45418063 3.693 APOC1
apolipoprotein C-I
chr6_-_26250832 3.668 NM_021018
HIST1H3J
HIST1H3F
histone cluster 1, H3j
histone cluster 1, H3f
chr20_-_32307889 3.659 NM_007238
NM_183397
PXMP4

peroxisomal membrane protein 4, 24kDa

chr19_+_50706868 3.654 NM_001077186
NM_001145809
NM_024729
MYH14


myosin, heavy chain 14, non-muscle


chr6_+_46097818 3.647 ENPP4
ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative)
chr19_-_41256349 3.644 C19orf54
chromosome 19 open reading frame 54
chr2_+_113033146 3.623 NM_198581
ZC3H6
zinc finger CCCH-type containing 6
chr6_-_30684851 3.612 MDC1
mediator of DNA-damage checkpoint 1
chr11_+_34654010 3.600 NM_001206616
EHF
ets homologous factor
chr17_-_1532109 3.595 NM_152346
SLC43A2
solute carrier family 43, member 2
chr17_-_63557615 3.578 NM_004655
AXIN2
axin 2
chr6_-_26271588 3.537 NM_003534
HIST1H3G
histone cluster 1, H3g
chr19_+_36505409 3.532


chr6_+_26156558 3.497 NM_005321
HIST1H1E
histone cluster 1, H1e
chr10_-_43187174 3.496


chr1_-_206137430 3.466 LOC100132966
uncharacterized LOC100132966
chr4_-_89744154 3.452 NM_001015045
FAM13A
family with sequence similarity 13, member A
chr6_+_89791510 3.447 PNRC1
proline-rich nuclear receptor coactivator 1
chr20_+_306205 3.446 NM_006943
SOX12
SRY (sex determining region Y)-box 12
chr19_-_41256371 3.437 C19orf54
chromosome 19 open reading frame 54
chr5_+_137514753 3.430 KIF20A
kinesin family member 20A
chr14_-_73360792 3.405 NM_012074
DPF3
D4, zinc and double PHD fingers, family 3
chr19_-_40324747 3.390 NM_004714
NM_006483
NM_006484
DYRK1B


dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1B


chr2_+_65216482 3.383 NM_003038
SLC1A4
solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
chr6_-_30685457 3.367 NM_014641
MDC1
mediator of DNA-damage checkpoint 1
chr5_+_137514416 3.363 NM_005733
KIF20A
kinesin family member 20A
chr6_-_41040160 3.359 NM_145063
C6orf130
chromosome 6 open reading frame 130
chr6_+_27775898 3.352 NM_003509
HIST1H2AI
HIST1H2AM
HIST1H3F
histone cluster 1, H2ai
histone cluster 1, H2am
histone cluster 1, H3f
chr5_-_150284503 3.341 NM_001172831
NM_001172832
NM_052860
ZNF300


zinc finger protein 300


chr22_-_38577692 3.337 NM_001004426
NM_003560
NM_001199562
PLA2G6


phospholipase A2, group VI (cytosolic, calcium-independent)


chr1_+_28585959 3.327 NM_031459
SESN2
sestrin 2
chr12_-_123717645 3.324 MPHOSPH9
M-phase phosphoprotein 9
chr1_-_68962679 3.310 DEPDC1
DEP domain containing 1
chr4_+_1873035 3.284 NM_001042424
WHSC1
Wolf-Hirschhorn syndrome candidate 1
chr7_-_148581359 3.268 EZH2
enhancer of zeste homolog 2 (Drosophila)
chr19_+_19174792 3.266 NM_178526
SLC25A42
solute carrier family 25, member 42
chr21_+_47744032 3.242 NM_006031
PCNT
pericentrin
chr5_+_59784004 3.233 PART1
prostate androgen-regulated transcript 1 (non-protein coding)
chr19_+_45417920 3.225 NM_001645
APOC1
apolipoprotein C-I
chr20_-_54967221 3.217 NM_003600
NM_198433
NM_198434
NM_198435
NM_198436
NM_198437
AURKA





aurora kinase A





chr2_+_150187028 3.202 NM_194317
LYPD6
LY6/PLAUR domain containing 6
chr22_+_41777932 3.196 NM_003216
TEF
thyrotrophic embryonic factor
chr2_-_86564632 3.163 NM_001164731
NM_001164732
NM_022912
REEP1


receptor accessory protein 1


chr5_+_156887026 3.163 NM_001099287
NM_001172292
NIPAL4

NIPA-like domain containing 4

chr5_-_137667453 3.159 NM_001790
NM_022809
CDC25C

cell division cycle 25 homolog C (S. pombe)

chr22_+_19467413 3.140 NM_001178010
NM_001178011
NM_003504
CDC45


cell division cycle 45 homolog (S. cerevisiae)


chr16_+_23690191 3.136 NM_005030
PLK1
polo-like kinase 1
chr1_-_152061529 3.124 NM_001008536
TCHHL1
trichohyalin-like 1
chr1_-_68962726 3.121 NM_001114120
NM_017779
DEPDC1

DEP domain containing 1

chr3_+_172468469 3.117 ECT2
epithelial cell transforming sequence 2 oncogene
chr16_+_23690212 3.111 PLK1
polo-like kinase 1
chr16_-_54320367 3.091 NM_024336
IRX3
iroquois homeobox 3
chr22_+_19467467 3.090 CDC45
cell division cycle 45 homolog (S. cerevisiae)
chr5_+_137203559 3.088 MYOT
myotilin
chr11_+_34642587 3.047 NM_001206615
NM_012153
EHF

ets homologous factor

chr1_-_23694497 3.035 NM_030634
ZNF436
zinc finger protein 436
chr17_-_41977966 3.027 MPP2
membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
chr17_+_46125675 3.021 NM_003204
NFE2L1
nuclear factor (erythroid-derived 2)-like 1
chr10_+_102133599 3.017 LINC00263
long intergenic non-protein coding RNA 263
chr16_+_23690190 3.013 PLK1
polo-like kinase 1
chr12_+_53662000 3.007 NM_012291
ESPL1
extra spindle pole bodies homolog 1 (S. cerevisiae)
chr16_+_23690160 2.987 PLK1
polo-like kinase 1
chr1_-_45140117 2.981 TMEM53
transmembrane protein 53
chr17_-_19281494 2.974 NM_001243475
B9D1
B9 protein domain 1
chr19_-_11266451 2.973 NM_182513
SPC24
SPC24, NDC80 kinetochore complex component, homolog (S. cerevisiae)
chr20_-_39317875 2.968 NM_005461
MAFB
v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian)
chr17_+_46125725 2.957 NFE2L1
nuclear factor (erythroid-derived 2)-like 1
chr2_+_113033184 2.955 ZC3H6
zinc finger CCCH-type containing 6
chrX_-_101771641 2.942 NM_021992
TMSB15A
TMSB15B
thymosin beta 15a
thymosin beta 15B
chr11_-_96076328 2.939 NM_032427
MAML2
mastermind-like 2 (Drosophila)
chr5_-_150284293 2.933 ZNF300
zinc finger protein 300
chr1_-_45140062 2.933 NM_024587
TMEM53
transmembrane protein 53
chr15_+_98503938 2.911 ARRDC4
arrestin domain containing 4
chr15_+_99645152 2.901 NM_015286
NM_145728
SYNM

synemin, intermediate filament protein

chr15_+_98503907 2.898 NM_183376
ARRDC4
arrestin domain containing 4
chr2_+_171034654 2.886 NM_001083615
NM_001171642
NM_138995
MYO3B


myosin IIIB


chr6_+_31707724 2.872 NM_002441
NM_025259
NM_172165
NM_172166
MSH5-C6orf26
MSH5



MSH5-C6orf26 readthrough (non-protein coding)
mutS homolog 5 (E. coli)



chr8_+_27631902 2.856 NM_001017420
ESCO2
establishment of cohesion 1 homolog 2 (S. cerevisiae)
chr14_-_23388380 2.853 NM_001077351
NM_001077352
NM_018107
RBM23


RNA binding motif protein 23


chr5_-_137514299 2.850 NM_001164326
NM_006696
NM_139199
BRD8


bromodomain containing 8


chr17_+_57232859 2.842 NM_018304
PRR11
proline rich 11
chrX_+_103217192 2.837 NM_194324
TMSB15B
thymosin beta 15B
chr5_-_39203061 2.806 FYB
FYN binding protein
chr13_+_97874704 2.805 MBNL2
muscleblind-like 2 (Drosophila)
chr4_+_1873149 2.797 WHSC1
Wolf-Hirschhorn syndrome candidate 1
chr17_+_46125724 2.795 NFE2L1
nuclear factor (erythroid-derived 2)-like 1
chr7_+_142982039 2.757 NM_001242773
NM_001242774
NM_001242775
NM_001242776
NM_001242777
NM_153345
TMEM139





transmembrane protein 139





chr12_-_110505499 2.750 NM_207435
C12orf76
chromosome 12 open reading frame 76
chr1_-_143913118 2.747 NM_207418
FAM72D
family with sequence similarity 72, member D
chr16_+_23690234 2.737 PLK1
polo-like kinase 1
chr1_+_120839004 2.735 NM_001100910
FAM72B
family with sequence similarity 72, member B
chr13_+_97874540 2.731 NM_144778
NM_207304
MBNL2

muscleblind-like 2 (Drosophila)

chr5_-_151150939 2.708 LOC100652758
uncharacterized LOC100652758
chr11_+_113930430 2.703 NM_006006
ZBTB16
zinc finger and BTB domain containing 16
chr11_+_1411089 2.699 NM_003957
BRSK2
BR serine/threonine kinase 2
chr4_-_82392971 2.699 RASGEF1B
RasGEF domain family, member 1B

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
3.12 1.21e-17 GO:0007049 cell cycle
3.21 2.12e-14 GO:0022402 cell cycle process
4.00 1.52e-12 GO:0000279 M phase
3.51 2.02e-12 GO:0000278 mitotic cell cycle
3.26 2.12e-12 GO:0022403 cell cycle phase
3.24 9.02e-11 GO:0051276 chromosome organization
2.23 1.10e-10 GO:0006996 organelle organization
4.29 7.69e-10 GO:0000087 M phase of mitotic cell cycle
1.84 1.89e-09 GO:0071842 cellular component organization at cellular level
3.80 1.24e-08 GO:0051301 cell division
1.78 2.23e-08 GO:0071841 cellular component organization or biogenesis at cellular level
1.67 2.63e-08 GO:0016043 cellular component organization
4.03 4.49e-08 GO:0000280 nuclear division
4.03 4.49e-08 GO:0007067 mitosis
5.87 7.00e-08 GO:0006323 DNA packaging
3.90 1.03e-07 GO:0048285 organelle fission
6.36 1.41e-07 GO:0065004 protein-DNA complex assembly
5.52 2.29e-07 GO:0006333 chromatin assembly or disassembly
1.62 2.82e-07 GO:0071840 cellular component organization or biogenesis
6.02 3.79e-07 GO:0071824 protein-DNA complex subunit organization
1.80 7.66e-07 GO:0051252 regulation of RNA metabolic process
6.56 8.51e-07 GO:0006334 nucleosome assembly
1.82 9.30e-07 GO:0006355 regulation of transcription, DNA-dependent
5.04 1.32e-06 GO:0071103 DNA conformation change
1.75 1.55e-06 GO:2000112 regulation of cellular macromolecule biosynthetic process
6.22 2.01e-06 GO:0031497 chromatin assembly
3.85 2.47e-06 GO:0007017 microtubule-based process
1.72 3.34e-06 GO:0010556 regulation of macromolecule biosynthetic process
2.69 3.64e-06 GO:0051726 regulation of cell cycle
5.91 4.49e-06 GO:0034728 nucleosome organization
1.68 6.28e-06 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
3.02 6.90e-06 GO:0008283 cell proliferation
8.69 1.06e-05 GO:0007051 spindle organization
1.57 1.07e-05 GO:0060255 regulation of macromolecule metabolic process
1.66 1.19e-05 GO:0009889 regulation of biosynthetic process
3.30 1.20e-05 GO:0010564 regulation of cell cycle process
1.66 1.25e-05 GO:0031326 regulation of cellular biosynthetic process
1.67 1.74e-05 GO:0010468 regulation of gene expression
1.64 1.76e-05 GO:0051171 regulation of nitrogen compound metabolic process
1.53 2.47e-05 GO:0080090 regulation of primary metabolic process
8.87 3.63e-05 GO:0000819 sister chromatid segregation
5.51 3.75e-05 GO:0007059 chromosome segregation
3.85 4.08e-05 GO:0071156 regulation of cell cycle arrest
3.83 9.18e-05 GO:0000075 cell cycle checkpoint
1.50 1.08e-04 GO:0031323 regulation of cellular metabolic process
8.66 2.07e-04 GO:0000070 mitotic sister chromatid segregation
1.45 2.59e-04 GO:0019222 regulation of metabolic process
2.65 6.50e-04 GO:0006325 chromatin organization
4.10 1.12e-03 GO:0000226 microtubule cytoskeleton organization
1.98 1.47e-03 GO:0022607 cellular component assembly
1.27 1.56e-03 GO:0050794 regulation of cellular process
2.15 3.64e-03 GO:0071844 cellular component assembly at cellular level
1.60 4.27e-03 GO:0048523 negative regulation of cellular process
1.22 8.09e-03 GO:0065007 biological regulation
1.77 3.84e-02 GO:0044085 cellular component biogenesis
2.81 4.42e-02 GO:0007346 regulation of mitotic cell cycle
1.21 4.78e-02 GO:0050789 regulation of biological process

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
4.20 1.27e-16 GO:0044427 chromosomal part
3.86 1.32e-16 GO:0005694 chromosome
5.25 2.84e-13 GO:0000785 chromatin
1.52 1.50e-12 GO:0005634 nucleus
1.76 2.55e-09 GO:0043228 non-membrane-bounded organelle
1.76 2.55e-09 GO:0043232 intracellular non-membrane-bounded organelle
1.23 1.30e-07 GO:0043229 intracellular organelle
1.23 1.68e-07 GO:0043226 organelle
5.11 3.88e-07 GO:0000793 condensed chromosome
2.57 6.52e-07 GO:0015630 microtubule cytoskeleton
1.24 1.46e-06 GO:0043231 intracellular membrane-bounded organelle
1.24 1.68e-06 GO:0043227 membrane-bounded organelle
1.16 7.88e-06 GO:0044424 intracellular part
1.35 1.54e-05 GO:0044446 intracellular organelle part
1.35 1.75e-05 GO:0044422 organelle part
7.10 1.82e-05 GO:0000786 nucleosome
1.15 2.40e-05 GO:0005622 intracellular
3.97 6.31e-05 GO:0044454 nuclear chromosome part
1.72 8.03e-05 GO:0031981 nuclear lumen
5.23 8.29e-05 GO:0032993 protein-DNA complex
3.77 1.41e-04 GO:0005819 spindle
1.62 2.35e-04 GO:0044428 nuclear part
3.38 4.02e-04 GO:0000228 nuclear chromosome
1.73 5.38e-04 GO:0005856 cytoskeleton
2.93 8.22e-04 GO:0005874 microtubule
4.84 1.32e-03 GO:0000776 kinetochore
3.75 2.32e-03 GO:0000775 chromosome, centromeric region
5.38 3.12e-03 GO:0000922 spindle pole
10.14 4.10e-03 GO:0000795 synaptonemal complex
1.82 4.18e-03 GO:0044430 cytoskeletal part
5.81 4.48e-03 GO:0000794 condensed nuclear chromosome
1.71 5.51e-03 GO:0005654 nucleoplasm
4.93 6.83e-03 GO:0000777 condensed chromosome kinetochore
2.92 9.90e-03 GO:0005813 centrosome
1.49 1.12e-02 GO:0070013 intracellular organelle lumen
4.61 1.24e-02 GO:0000779 condensed chromosome, centromeric region
1.47 1.37e-02 GO:0043233 organelle lumen
1.45 2.46e-02 GO:0031974 membrane-enclosed lumen
2.41 2.62e-02 GO:0005815 microtubule organizing center
5.07 3.55e-02 GO:0016605 PML body

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
1.88 6.61e-10 GO:0003677 DNA binding
2.37 2.59e-05 GO:0043565 sequence-specific DNA binding
1.13 1.17e-04 GO:0005488 binding
1.48 1.18e-04 GO:0003676 nucleic acid binding
3.44 1.29e-03 GO:0003682 chromatin binding
5.35 1.48e-03 GO:0003777 microtubule motor activity
1.91 1.53e-03 GO:0001071 nucleic acid binding transcription factor activity
1.91 1.53e-03 GO:0003700 sequence-specific DNA binding transcription factor activity
1.79 1.28e-02 GO:0030528 transcription regulator activity
3.30 4.19e-02 GO:0003774 motor activity