Motif ID: FOXN1.p2

Z-value: 0.933


Transcription factors associated with FOXN1.p2:

Gene SymbolEntrez IDGene Name
FOXN1 8456 forkhead box N1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
FOXN1hg19_v1_chr17_+_26850958_26850958-0.171.5e-01Click!


Activity profile for motif FOXN1.p2.

activity profile for motif FOXN1.p2


Sorted Z-values histogram for motif FOXN1.p2

Sorted Z-values for motif FOXN1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of FOXN1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_+_126070813 4.366 HEY2
hairy/enhancer-of-split related with YRPW motif 2
chr11_+_65554566 3.723 OVOL1
ovo-like 1(Drosophila)
chr6_-_24911194 3.702 NM_014722
FAM65B
family with sequence similarity 65, member B
chr11_+_65554504 3.481 NM_004561
OVOL1
ovo-like 1(Drosophila)
chr11_+_61447816 3.120 NM_006133
DAGLA
diacylglycerol lipase, alpha
chr21_+_15588465 2.536 NM_144770
RBM11
RNA binding motif protein 11
chr6_+_126070724 2.420 NM_012259
HEY2
hairy/enhancer-of-split related with YRPW motif 2
chrX_-_153775427 2.323 G6PD
glucose-6-phosphate dehydrogenase
chrX_-_153775064 2.248 NM_000402
G6PD
glucose-6-phosphate dehydrogenase
chr6_+_126070738 2.141 HEY2
hairy/enhancer-of-split related with YRPW motif 2
chr7_-_120498009 2.036 TSPAN12
tetraspanin 12
chr20_+_61273786 1.966 NM_016354
SLCO4A1
solute carrier organic anion transporter family, member 4A1
chr4_+_3768295 1.892 NM_000683
ADRA2C
adrenergic, alpha-2C-, receptor
chr14_-_77494974 1.849 NM_024496
IRF2BPL
interferon regulatory factor 2 binding protein-like
chr20_+_61273823 1.806 SLCO4A1
solute carrier organic anion transporter family, member 4A1
chr19_+_12902286 1.801


chr19_-_47164289 1.772 NM_145056
DACT3
dapper, antagonist of beta-catenin, homolog 3 (Xenopus laevis)
chr19_-_49496520 1.754 GYS1
glycogen synthase 1 (muscle)
chr11_+_1860232 1.732 NM_003282
TNNI2
troponin I type 2 (skeletal, fast)
chr14_-_53417272 1.722 FERMT2
fermitin family member 2
chr19_-_49496566 1.677 NM_001161587
NM_002103
GYS1

glycogen synthase 1 (muscle)

chr3_-_87040268 1.675 VGLL3
vestigial like 3 (Drosophila)
chr3_-_87040246 1.665 NM_016206
VGLL3
vestigial like 3 (Drosophila)
chr2_+_113403433 1.631 NM_005415
SLC20A1
solute carrier family 20 (phosphate transporter), member 1
chr19_-_49496564 1.614 GYS1
glycogen synthase 1 (muscle)
chr19_-_49496369 1.599 GYS1
glycogen synthase 1 (muscle)
chr11_-_32457059 1.584 NM_000378
NM_024424
NM_024426
WT1


Wilms tumor 1


chr12_-_12715244 1.561 NM_030640
DUSP16
dual specificity phosphatase 16
chr11_-_65430545 1.535


chr19_-_56110851 1.510 NM_032836
FIZ1
FLT3-interacting zinc finger 1
chr12_+_104609501 1.487 NM_001093771
TXNRD1
thioredoxin reductase 1
chr19_+_39109807 1.482 EIF3K
eukaryotic translation initiation factor 3, subunit K
chr19_+_39109831 1.461 EIF3K
eukaryotic translation initiation factor 3, subunit K
chr19_+_39109847 1.461 EIF3K
eukaryotic translation initiation factor 3, subunit K
chr1_-_32707198 1.420 MTMR9LP
myotubularin related protein 9-like, pseudogene
chr17_-_43510279 1.392 NM_174919
ARHGAP27
Rho GTPase activating protein 27
chr3_+_156393357 1.391 TIPARP
TCDD-inducible poly(ADP-ribose) polymerase
chr10_+_72163899 1.383 EIF4EBP2
eukaryotic translation initiation factor 4E binding protein 2
chr3_+_47021146 1.376 NM_015175
NBEAL2
neurobeachin-like 2
chr7_-_50860665 1.344 GRB10
growth factor receptor-bound protein 10
chr15_+_81293286 1.310 NM_022566
MESDC1
mesoderm development candidate 1
chr19_-_46389307 1.304 NM_015649
IRF2BP1
interferon regulatory factor 2 binding protein 1
chr2_-_73520448 1.275 NM_001965
EGR4
early growth response 4
chr19_+_45349392 1.257 NM_001042724
NM_002856
PVRL2

poliovirus receptor-related 2 (herpesvirus entry mediator B)

chr16_-_71264596 1.240 NM_001198542
NM_001198543
HYDIN

hydrocephalus inducing homolog (mouse)

chr17_-_43510204 1.234 ARHGAP27
Rho GTPase activating protein 27
chr1_+_82266081 1.231 NM_012302
LPHN2
latrophilin 2
chr1_-_1243246 1.225 NM_030649
ACAP3
ArfGAP with coiled-coil, ankyrin repeat and PH domains 3
chr3_+_183165402 1.217 LOC100505687
uncharacterized LOC100505687
chr19_-_59070324 1.217 NM_003969
UBE2M
ubiquitin-conjugating enzyme E2M
chr17_-_64187814 1.212 NM_145036
NM_001199165
CEP112

centrosomal protein 112kDa

chr10_+_123922940 1.210 TACC2
transforming, acidic coiled-coil containing protein 2
chr8_-_133687761 1.204 NM_012472
LRRC6
leucine rich repeat containing 6
chr19_-_49014832 1.199


chr2_-_130956011 1.181 NM_207312
TUBA3E
tubulin, alpha 3e
chr19_+_39109684 1.180 NM_013234
EIF3K
eukaryotic translation initiation factor 3, subunit K
chr16_+_725679 1.177 RHBDL1
rhomboid, veinlet-like 1 (Drosophila)
chr15_-_74726258 1.156 NM_001146029
NM_003612
SEMA7A

semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)

chr16_+_71929432 1.152 NM_014761
IST1
increased sodium tolerance 1 homolog (yeast)
chr12_+_104680712 1.119 NM_003330
NM_182729
NM_182742
NM_182743
TXNRD1



thioredoxin reductase 1



chr15_+_73976537 1.110


chr14_-_38064440 1.095 NM_004496
FOXA1
forkhead box A1
chr1_-_12677347 1.087 NM_004753
DHRS3
dehydrogenase/reductase (SDR family) member 3
chr16_+_71929399 1.064 IST1
increased sodium tolerance 1 homolog (yeast)
chrX_-_153775774 1.063 NM_001042351
G6PD
glucose-6-phosphate dehydrogenase
chr15_+_41221530 1.052 NM_019074
DLL4
delta-like 4 (Drosophila)
chr5_+_32710742 1.048 NM_001204376
NPR3
natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)
chr12_+_57943843 1.026 NM_004984
KIF5A
kinesin family member 5A
chr3_-_150480963 1.016 NM_005067
SIAH2
seven in absentia homolog 2 (Drosophila)
chr14_-_53417636 1.015 FERMT2
fermitin family member 2
chr5_+_176873795 1.007 NM_001174101
NM_030567
PRR7

proline rich 7 (synaptic)

chr5_+_149340437 1.003 SLC26A2
solute carrier family 26 (sulfate transporter), member 2
chr3_-_197463713 1.000 NM_014687
KIAA0226
KIAA0226
chr15_-_101459410 0.997


chr5_+_179248089 0.993 SQSTM1
sequestosome 1
chr19_+_48949217 0.989 GRWD1
glutamate-rich WD repeat containing 1
chr3_+_158288952 0.986 NM_001130156
NM_001130157
NM_001195432
NM_001195433
NM_001195434
NM_022443
MLF1





myeloid leukemia factor 1





chr1_+_101361671 0.984 SLC30A7
solute carrier family 30 (zinc transporter), member 7
chr19_+_48949241 0.982 GRWD1
glutamate-rich WD repeat containing 1
chr19_+_39109848 0.961 EIF3K
eukaryotic translation initiation factor 3, subunit K
chr19_-_4066739 0.952 NM_015898
ZBTB7A
zinc finger and BTB domain containing 7A
chr7_+_96746993 0.951 ACN9
ACN9 homolog (S. cerevisiae)
chr3_+_150803448 0.948 MED12L
mediator complex subunit 12-like
chr15_+_78730568 0.946 IREB2
iron-responsive element binding protein 2
chr1_-_211751719 0.945 SLC30A1
solute carrier family 30 (zinc transporter), member 1
chr2_-_175869910 0.942 NM_001822
NM_001025201
CHN1

chimerin (chimaerin) 1

chr2_+_30670082 0.942 NM_182551
NM_001002257
LCLAT1

lysocardiolipin acyltransferase 1

chr1_+_101361589 0.940 NM_001144884
NM_133496
SLC30A7

solute carrier family 30 (zinc transporter), member 7

chr5_+_149340346 0.920 SLC26A2
solute carrier family 26 (sulfate transporter), member 2
chr5_+_149340287 0.920 NM_000112
SLC26A2
solute carrier family 26 (sulfate transporter), member 2
chr1_+_53068042 0.918 NM_015696
GPX6
GPX7
glutathione peroxidase 6 (olfactory)
glutathione peroxidase 7
chrX_-_108868250 0.905 NM_012282
KCNE1L
KCNE1-like
chr8_+_38243958 0.905 NM_001199659
NM_144652
LETM2

leucine zipper-EF-hand containing transmembrane protein 2

chr2_+_27994586 0.896 MRPL33
mitochondrial ribosomal protein L33
chr19_-_42806928 0.894 NM_001145939
NM_001145940
PAFAH1B3

platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)

chr2_+_27994581 0.891 NM_004891
NM_145330
MRPL33

mitochondrial ribosomal protein L33

chr10_+_72163914 0.890 EIF4EBP2
eukaryotic translation initiation factor 4E binding protein 2
chr19_+_12902295 0.889 NM_002229
JUNB
jun B proto-oncogene
chr19_+_1249882 0.885 MIDN
midnolin
chr17_+_78518611 0.880 NM_001163034
NM_020761
RPTOR

regulatory associated protein of MTOR, complex 1

chr2_-_230135954 0.875 NM_001100818
NM_017933
PID1

phosphotyrosine interaction domain containing 1

chr16_-_57318452 0.874 PLLP
plasmolipin
chr19_-_59084089 0.874 MZF1
myeloid zinc finger 1
chr19_+_58898634 0.874 NM_001009
RPS5
ribosomal protein S5
chr16_-_75498497 0.873 TMEM170A
transmembrane protein 170A
chr6_-_30654406 0.869 PPP1R18
protein phosphatase 1, regulatory subunit 18
chr19_-_46295785 0.867 NM_004943
DMWD
dystrophia myotonica, WD repeat containing
chr3_-_120461350 0.859


chr13_-_24463430 0.858 NM_005932
MIPEP
mitochondrial intermediate peptidase
chr19_-_55918980 0.853 UBE2S
ubiquitin-conjugating enzyme E2S
chr5_+_172261220 0.851 NM_001031711
ERGIC1
endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1
chr19_+_38397880 0.848 SIPA1L3
signal-induced proliferation-associated 1 like 3
chr19_+_39971448 0.848 TIMM50
translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
chr19_+_39971488 0.845 TIMM50
translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
chr17_+_56065408 0.842


chr11_-_32456910 0.835 WT1
Wilms tumor 1
chr1_-_47082529 0.834 NM_201403
MOB3C
MOB kinase activator 3C
chr11_-_119252364 0.833 NM_001243759
NM_004205
USP2

ubiquitin specific peptidase 2

chr17_-_38210611 0.824 MED24
mediator complex subunit 24
chr1_+_101361688 0.820 SLC30A7
solute carrier family 30 (zinc transporter), member 7
chr11_-_67141008 0.820 NM_013246
CLCF1
cardiotrophin-like cytokine factor 1
chr17_-_79885544 0.819 NM_002359
MAFG
v-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian)
chr19_-_55769920 0.818 NM_014931
PPP6R1
protein phosphatase 6, regulatory subunit 1
chr16_-_71757650 0.807 PHLPP2
PH domain and leucine rich repeat protein phosphatase 2
chr3_+_156544075 0.806 NM_001004316
NM_001193283
LEKR1

leucine, glutamate and lysine rich 1

chr5_-_73937248 0.801 NM_003633
ENC1
ectodermal-neural cortex 1 (with BTB-like domain)
chr1_+_101361649 0.800 SLC30A7
solute carrier family 30 (zinc transporter), member 7
chr9_-_99775855 0.799 HIATL2
hippocampus abundant transcript-like 2
chr15_-_23034365 0.796 NIPA2
non imprinted in Prader-Willi/Angelman syndrome 2
chr10_+_123923104 0.795 NM_006997
NM_206860
TACC2

transforming, acidic coiled-coil containing protein 2

chr19_+_56159400 0.794 CCDC106
coiled-coil domain containing 106
chr5_+_179247903 0.790 SQSTM1
sequestosome 1
chr19_+_18118921 0.789 NM_015683
ARRDC2
arrestin domain containing 2
chr14_-_53417808 0.786 NM_001134999
NM_001135000
NM_006832
FERMT2


fermitin family member 2


chr3_-_120461362 0.784 NM_173825
RABL3
RAB, member of RAS oncogene family-like 3
chr19_+_41305041 0.783 NM_080732
EGLN2
egl nine homolog 2 (C. elegans)
chr5_+_76506705 0.779 NM_001029851
NM_001029852
NM_001029853
NM_001029854
NM_003719
PDE8B




phosphodiesterase 8B




chr16_+_50582193 0.776 NM_033119
NKD1
naked cuticle homolog 1 (Drosophila)
chr19_+_39971496 0.775 TIMM50
translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
chr1_-_36851484 0.774 NM_032017
STK40
serine/threonine kinase 40
chr19_-_54693517 0.774 NM_001146056
NM_001146082
NM_001146083
NM_024298
MBOAT7



membrane bound O-acyltransferase domain containing 7



chr15_-_23034307 0.770 NIPA2
non imprinted in Prader-Willi/Angelman syndrome 2
chr17_-_2304217 0.767 NM_020310
MNT
MAX binding protein
chr8_-_11324184 0.767 NM_053279
FAM167A
family with sequence similarity 167, member A
chr2_+_132233579 0.766 NM_080386
TUBA3D
tubulin, alpha 3d
chr19_-_55769844 0.764 PPP6R1
protein phosphatase 6, regulatory subunit 1
chrX_-_15353634 0.762 PIGA
phosphatidylinositol glycan anchor biosynthesis, class A
chr1_+_227058241 0.761 NM_000447
NM_012486
PSEN2

presenilin 2 (Alzheimer disease 4)

chr11_-_61062534 0.757 VWCE
von Willebrand factor C and EGF domains
chr1_-_241683060 0.756 NM_000143
FH
fumarate hydratase
chr3_-_48936227 0.754 NM_000387
SLC25A20
solute carrier family 25 (carnitine/acylcarnitine translocase), member 20
chr16_-_57318574 0.746 NM_015993
PLLP
plasmolipin
chr1_-_52344306 0.745 NRD1
nardilysin (N-arginine dibasic convertase)
chr3_+_160473995 0.742 NM_139245
PPM1L
protein phosphatase, Mg2+/Mn2+ dependent, 1L
chr19_+_54960380 0.742 LENG8
leukocyte receptor cluster (LRC) member 8
chr15_-_74726000 0.738 NM_001146030
SEMA7A
semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
chr1_-_241683011 0.736 FH
fumarate hydratase
chr19_+_46498695 0.736 CCDC61
coiled-coil domain containing 61
chr15_+_52472257 0.724 LOC100129973
uncharacterized LOC100129973
chr13_-_21635629 0.723 LATS2
LATS, large tumor suppressor, homolog 2 (Drosophila)
chr12_+_57943780 0.718 KIF5A
kinesin family member 5A
chr4_+_77227882 0.718 STBD1
starch binding domain 1
chr17_+_78518742 0.718 RPTOR
regulatory associated protein of MTOR, complex 1
chr19_+_59070557 0.717 LOC100131691
uncharacterized LOC100131691
chr7_+_76751933 0.716 NM_020879
CCDC146
coiled-coil domain containing 146
chr18_+_18822168 0.715 NM_001142966
GREB1L
growth regulation by estrogen in breast cancer-like
chr16_+_50776012 0.711 NM_001042412
CYLD
cylindromatosis (turban tumor syndrome)
chr1_+_9294857 0.709 NM_004285
H6PD
hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
chr8_-_11058847 0.705 NM_173683
XKR6
XK, Kell blood group complex subunit-related family, member 6
chr14_+_105190533 0.700 NM_152328
ADSSL1
adenylosuccinate synthase like 1
chr16_-_71264557 0.700 NM_032821
NM_017558
HYDIN

hydrocephalus inducing homolog (mouse)

chr20_-_62610990 0.699 NM_080621
SAMD10
sterile alpha motif domain containing 10
chr19_-_9929682 0.698 NM_017703
FBXL12
F-box and leucine-rich repeat protein 12
chr10_+_70715883 0.695 NM_004728
DDX21
DEAD (Asp-Glu-Ala-Asp) box polypeptide 21
chr17_-_78120759 0.694 NM_014740
EIF4A3
eukaryotic translation initiation factor 4A3
chr5_-_134369571 0.693 PITX1
paired-like homeodomain 1
chr17_+_7342688 0.691 NM_004112
FGF11
fibroblast growth factor 11
chr1_-_167905078 0.691 BRP44
brain protein 44
chrX_-_71525763 0.689 NM_001144885
NM_001144887
CITED1

Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1

chr1_-_91487586 0.689 ZNF644
zinc finger protein 644
chr5_+_60628085 0.687 NM_020928
ZSWIM6
zinc finger, SWIM-type containing 6
chr6_+_74171453 0.687 NM_001123226
NM_012123
NM_133645
MTO1


mitochondrial translation optimization 1 homolog (S. cerevisiae)


chr14_-_59951042 0.684 NM_144581
C14orf149
chromosome 14 open reading frame 149
chr4_+_184427224 0.684 ING2
inhibitor of growth family, member 2
chr19_-_38806381 0.683 NM_001039671
NM_001145461
NM_001145462
YIF1B


Yip1 interacting factor homolog B (S. cerevisiae)


chr3_-_47205413 0.683 NM_014159
SETD2
SET domain containing 2
chr4_+_148538564 0.681 TMEM184C
transmembrane protein 184C
chr15_-_23034406 0.681 NM_001008860
NM_001008892
NM_001008894
NM_001184888
NM_001184889
NM_030922
NIPA2





non imprinted in Prader-Willi/Angelman syndrome 2





chrX_+_18443702 0.679 NM_003159
CDKL5
cyclin-dependent kinase-like 5
chr15_-_59665069 0.677 NM_004998
MYO1E
myosin IE
chr1_-_91487543 0.676 ZNF644
zinc finger protein 644
chrX_-_15353665 0.674 PIGA
phosphatidylinositol glycan anchor biosynthesis, class A
chr9_+_97021556 0.673 NM_194320
ZNF169
zinc finger protein 169
chr19_-_33793321 0.672


chr19_+_41305100 0.671 EGLN2
egl nine homolog 2 (C. elegans)
chr5_+_179247841 0.670 NM_003900
SQSTM1
sequestosome 1
chr19_-_46142662 0.669 NM_012155
EML2
echinoderm microtubule associated protein like 2
chr17_+_79670396 0.667 NM_002949
MRPL12
mitochondrial ribosomal protein L12
chr2_-_86116016 0.667 NM_003896
ST3GAL5
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
chr2_-_28113211 0.664 NM_022128
RBKS
ribokinase

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
122.39 9.23e-03 GO:0005536 glucose binding