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Motif ID: FEV.p2

Z-value: 1.310

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr19_+_15218141	17.305	NM_033025	SYDE1	synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
chr8_-_82395401	12.689	NM_001442	FABP4	fatty acid binding protein 4, adipocyte
chr1_+_154300275	12.546	NM_020452	ATP8B2	ATPase, class I, type 8B, member 2
chr16_-_31214054	11.274	NM_013258 NM_145182	PYCARD	PYD and CARD domain containing
chr20_+_44746889	9.323	NM_001250 NM_152854	CD40	CD40 molecule, TNF receptor superfamily member 5
chr17_+_67410825	9.231	NM_002758	MAP2K6	mitogen-activated protein kinase kinase 6
chr20_+_44746948	8.715		CD40	CD40 molecule, TNF receptor superfamily member 5
chr9_-_86571533	7.911		C9orf64	chromosome 9 open reading frame 64
chr5_+_140474198	7.662	NM_018936	PCDHB2	protocadherin beta 2
chr2_+_37571752	7.466	NM_012413	QPCT	glutaminyl-peptide cyclotransferase
chr5_-_102898450	6.986	NM_031438	NUDT12	nudix (nucleoside diphosphate linked moiety X)-type motif 12
chr1_-_151345156	6.516	NM_003944	SELENBP1	selenium binding protein 1
chr19_-_51523272	6.298	NM_002776 NM_001077500	KLK10	kallikrein-related peptidase 10
chr19_-_51522953	5.990	NM_145888	KLK10	kallikrein-related peptidase 10
chr17_-_46655544	5.944	NM_024015	HOXB4	homeobox B4
chr7_+_106505739	5.914		PIK3CG	phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr20_-_33460558	5.855	NM_178026	GGT7	gamma-glutamyltransferase 7
chr19_-_51456159	5.854	NM_001077491 NM_001077492 NM_012427	KLK5	kallikrein-related peptidase 5
chr2_+_182321933	5.779		ITGA4	integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
chr7_+_106505696	5.744		PIK3CG	phosphoinositide-3-kinase, catalytic, gamma polypeptide
chrX_-_64196268	5.587	NM_001178033 NM_018684	ZC4H2	zinc finger, C4H2 domain containing
chr19_+_44488331	5.242	NM_003445 NM_198089	ZNF155	zinc finger protein 155
chr3_-_64211111	5.187	NM_198859	PRICKLE2	prickle homolog 2 (Drosophila)
chr12_-_123214882	5.184	NM_032554	HCAR1	hydroxycarboxylic acid receptor 1
chrX_+_102632108	5.157	NM_014380	NGFRAP1	nerve growth factor receptor (TNFRSF16) associated protein 1
chr15_-_40600025	5.112		PLCB2	phospholipase C, beta 2
chr1_-_110933635	5.106		SLC16A4	solute carrier family 16, member 4 (monocarboxylic acid transporter 5)
chr8_-_79717540	5.030	NM_000880 NM_001199886 NM_001199887 NM_001199888	IL7	interleukin 7
chr6_-_32160637	4.981		GPSM3	G-protein signaling modulator 3
chr11_-_46722115	4.967	NM_004308	ARHGAP1	Rho GTPase activating protein 1
chr7_+_106505876	4.931	NM_002649	PIK3CG	phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr2_+_175260455	4.860	NM_001193528 NM_024583	SCRN3	secernin 3
chr17_+_38119225	4.607	NM_178171	GSDMA	gasdermin A
chr12_-_57871631	4.583	NM_001080156	ARHGAP9	Rho GTPase activating protein 9
chr15_-_40600118	4.568	NM_004573	PLCB2	phospholipase C, beta 2
chrX_-_153072265	4.504		PDZD4	PDZ domain containing 4
chr22_+_37257004	4.474	NM_000631 NM_013416	NCF4	neutrophil cytosolic factor 4, 40kDa
chr13_-_20805371	4.376	NM_006783	GJB6	gap junction protein, beta 6, 30kDa
chr1_+_152956563	4.355	NM_001199828 NM_005987	SPRR1A	small proline-rich protein 1A
chr1_-_110933683	4.346	NM_001201546 NM_001201547 NM_001201548 NM_001201549 NM_004696	SLC16A4	solute carrier family 16, member 4 (monocarboxylic acid transporter 5)
chr11_+_129245834	4.291	NM_003658	BARX2	BARX homeobox 2
chr15_-_40599872	4.263		PLCB2	phospholipase C, beta 2
chr1_-_150738255	4.227		CTSS	cathepsin S
chr19_-_12267528	4.203	NM_145233	ZNF625-ZNF20 ZNF625	ZNF625-ZNF20 readthrough zinc finger protein 625
chr19_+_48828820	4.136		EMP3	epithelial membrane protein 3
chr6_-_32160289	4.118		GPSM3	G-protein signaling modulator 3
chr2_+_175260505	4.093		SCRN3	secernin 3
chr12_+_48876285	4.065	NM_152319	C12orf54	chromosome 12 open reading frame 54
chr3_-_170626381	4.048		EIF5A2	eukaryotic translation initiation factor 5A2
chr19_+_48828627	3.952	NM_001425	EMP3	epithelial membrane protein 3
chr22_+_38201300	3.947		H1F0	H1 histone family, member 0
chr3_-_114343052	3.944	NM_001164347	ZBTB20	zinc finger and BTB domain containing 20
chr3_-_170626425	3.939	NM_020390	EIF5A2	eukaryotic translation initiation factor 5A2
chr5_+_52776479	3.912		FST	follistatin
chr1_+_161676761	3.872	NM_001184866 NM_001184867 NM_001184870 NM_001184871 NM_001184872 NM_001184873 NM_032738	FCRLA	Fc receptor-like A
chr9_+_33750463	3.752	NM_001197097 NM_007343 NM_001197098	PRSS3	protease, serine, 3
chrX_-_48931645	3.749	NM_007213	PRAF2	PRA1 domain family, member 2
chr1_-_114429996	3.724		BCL2L15	BCL2-like 15
chr19_+_37569307	3.654	NM_144689	ZNF420	zinc finger protein 420
chr10_+_49892860	3.645		WDFY4	WDFY family member 4
chr19_+_16999871	3.594		F2RL3	coagulation factor II (thrombin) receptor-like 3
chr16_-_31085503	3.569	NM_024706	ZNF668	zinc finger protein 668
chrX_-_84634396	3.530		POF1B	premature ovarian failure, 1B
chr10_-_72362441	3.525		PRF1	perforin 1 (pore forming protein)
chr10_-_1034280	3.507		LOC100288619	uncharacterized LOC100288619
chr12_+_89744714	3.480		LOC100131490	uncharacterized LOC100131490
chr10_-_72362513	3.478	NM_001083116 NM_005041	PRF1	perforin 1 (pore forming protein)
chr11_-_46722160	3.478		ARHGAP1	Rho GTPase activating protein 1
chr5_-_176037091	3.464	NM_052899	GPRIN1	G protein regulated inducer of neurite outgrowth 1
chr2_+_182321618	3.456	NM_000885	ITGA4	integrin, alpha 4 (antigen CD49D, alpha 4 subunit of VLA-4 receptor)
chr8_+_75736771	3.338	NM_015886	PI15	peptidase inhibitor 15
chr10_-_105212149	3.315	NM_015916	CALHM2	calcium homeostasis modulator 2
chr4_+_40198526	3.314	NM_004310	RHOH	ras homolog gene family, member H
chr15_+_23810808	3.287		MKRN3	makorin ring finger protein 3
chr6_+_153019029	3.268	NM_025107	MYCT1	myc target 1
chr8_-_143859638	3.267	NM_023946 NM_177457	LYNX1	Ly6/neurotoxin 1
chr11_+_46722564	3.236	NM_001184751	ZNF408	zinc finger protein 408
chr6_+_31553955	3.189	NM_205838 NM_205839	LST1	leukocyte specific transcript 1
chr16_+_29674564	3.187		SPN	sialophorin
chr1_+_198608216	3.186		PTPRC	protein tyrosine phosphatase, receptor type, C
chr5_+_57787260	3.162	NM_152687	GAPT	GRB2-binding adaptor protein, transmembrane
chr16_+_29674568	3.148	NM_003123	SPN	sialophorin
chr11_-_102714240	3.127	NM_002422	MMP3	matrix metallopeptidase 3 (stromelysin 1, progelatinase)
chr2_-_160919120	3.126	NM_001007267 NM_001195641 NM_007366	PLA2R1	phospholipase A2 receptor 1, 180kDa
chr10_-_98031154	3.120	NM_001114094 NM_013314	BLNK	B-cell linker
chr5_-_88178964	3.090		MEF2C	myocyte enhancer factor 2C
chr7_+_70231163	3.086		AUTS2	autism susceptibility candidate 2
chr16_+_29674282	3.073	NM_001030288	SPN	sialophorin
chr17_-_27948345	3.068	NM_032854	CORO6	coronin 6
chr1_+_169337193	3.034	NM_003666	BLZF1	basic leucine zipper nuclear factor 1
chr7_-_83278478	3.033	NM_012431	SEMA3E	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
chr1_-_79472360	2.994	NM_022159	ELTD1	EGF, latrophilin and seven transmembrane domain containing 1
chr6_+_107811272	2.991	NM_018013	SOBP	sine oculis binding protein homolog (Drosophila)
chr2_+_31456981	2.959		EHD3	EH-domain containing 3
chr2_-_27603584	2.938	NM_144631	ZNF513	zinc finger protein 513
chr16_-_325867	2.916	NM_003834 NM_183337	RGS11	regulator of G-protein signaling 11
chr10_-_5541401	2.914	NM_017422	CALML5	calmodulin-like 5
chr2_+_98330030	2.892	NM_001079	ZAP70	zeta-chain (TCR) associated protein kinase 70kDa
chr12_-_57873628	2.871	NM_032496	ARHGAP9	Rho GTPase activating protein 9
chr22_-_19512859	2.857	NM_001130861 NM_003277	CLDN5	claudin 5
chr12_+_41086189	2.836	NM_001843 NM_175038	CNTN1	contactin 1
chr14_+_77227783	2.831
chr1_+_169337432	2.823		BLZF1	basic leucine zipper nuclear factor 1
chr19_-_58238895	2.810	NM_024833	ZNF671	zinc finger protein 671
chr11_-_65667860	2.810	NM_005438	FOSL1	FOS-like antigen 1
chr11_-_64764388	2.800	NM_138456	BATF2	basic leucine zipper transcription factor, ATF-like 2
chrX_+_84498993	2.788	NM_021998	ZNF711	zinc finger protein 711
chr11_+_107799134	2.775	NM_017516	RAB39A	RAB39A, member RAS oncogene family
chr16_-_31214003	2.770		PYCARD	PYD and CARD domain containing
chr12_-_57873364	2.761	NM_001080157	ARHGAP9	Rho GTPase activating protein 9
chr1_+_198608244	2.759		PTPRC	protein tyrosine phosphatase, receptor type, C
chr11_-_46722139	2.751		ARHGAP1	Rho GTPase activating protein 1
chr7_-_3083346	2.747	NM_032415	CARD11	caspase recruitment domain family, member 11
chr5_+_52776408	2.708		FST	follistatin
chr3_+_38080695	2.688	NM_007335 NM_007337	DLEC1	deleted in lung and esophageal cancer 1
chr9_+_33795558	2.672	NM_002771	PRSS3	protease, serine, 3
chr5_+_178450775	2.669	NM_001136116	ZNF879	zinc finger protein 879
chr19_-_17375522	2.669	NM_031941	USHBP1	Usher syndrome 1C binding protein 1
chrX_-_84634664	2.659		POF1B	premature ovarian failure, 1B
chr11_+_22688156	2.656	NM_001143830	GAS2	growth arrest-specific 2
chr11_-_123848397	2.650	NM_001004474	OR10S1	olfactory receptor, family 10, subfamily S, member 1
chr20_+_49126920	2.646		PTPN1	protein tyrosine phosphatase, non-receptor type 1
chr5_-_54281345	2.639	NM_001135604 NM_007036	ESM1	endothelial cell-specific molecule 1
chr5_+_180581942	2.639	NM_206880	OR2V2	olfactory receptor, family 2, subfamily V, member 2
chr20_+_45523247	2.637	NM_005244 NM_172110	EYA2	eyes absent homolog 2 (Drosophila)
chr1_-_202129705	2.633		PTPN7	protein tyrosine phosphatase, non-receptor type 7
chr1_-_39407449	2.633	NM_017821	RHBDL2	rhomboid, veinlet-like 2 (Drosophila)
chr1_+_198608136	2.629	NM_002838 NM_080921 NM_080923	PTPRC	protein tyrosine phosphatase, receptor type, C
chr3_+_113251217	2.629	NM_017699	SIDT1	SID1 transmembrane family, member 1
chr20_-_56286540	2.616	NM_199171	PMEPA1	prostate transmembrane protein, androgen induced 1
chr10_+_81892429	2.608		PLAC9	placenta-specific 9
chr11_-_111412422	2.589
chr10_+_81892497	2.587		PLAC9	placenta-specific 9
chr3_-_183273407	2.581	NM_130446	KLHL6	kelch-like 6 (Drosophila)
chr2_+_31456879	2.574	NM_014600	EHD3	EH-domain containing 3
chr17_+_4981721	2.573	NM_153018	ZFP3	zinc finger protein 3 homolog (mouse)
chr17_+_4981754	2.573		ZFP3	zinc finger protein 3 homolog (mouse)
chr19_-_36246411	2.571		HSPB6	heat shock protein, alpha-crystallin-related, B6
chr4_+_152198324	2.569	NM_183375	PRSS48	protease, serine, 48
chr1_-_150738232	2.546		CTSS	cathepsin S
chr16_-_50715116	2.544		SNX20	sorting nexin 20
chr3_+_173116243	2.541	NM_014932	NLGN1	neuroligin 1
chr16_+_30483959	2.531	NM_001114380 NM_002209	ITGAL	integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
chr11_-_75141210	2.530		KLHL35	kelch-like 35 (Drosophila)
chr18_-_61329113	2.528	NM_006919	SERPINB3	serpin peptidase inhibitor, clade B (ovalbumin), member 3
chrX_-_84634742	2.522	NM_024921	POF1B	premature ovarian failure, 1B
chrX_-_64254592	2.522	NM_001178032 NM_001243804	ZC4H2	zinc finger, C4H2 domain containing
chr19_+_16999807	2.522	NM_003950	F2RL3	coagulation factor II (thrombin) receptor-like 3
chr17_-_16875388	2.512	NM_012452	TNFRSF13B	tumor necrosis factor receptor superfamily, member 13B
chr20_+_49126908	2.509		PTPN1	protein tyrosine phosphatase, non-receptor type 1
chr19_-_51413993	2.494	NM_004917	KLK4	kallikrein-related peptidase 4
chr16_+_30484049	2.491		ITGAL	integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
chr1_-_150738292	2.489	NM_001199739 NM_004079	CTSS	cathepsin S
chr19_+_12273866	2.488	NM_003437	ZNF136	zinc finger protein 136
chr16_+_1583666	2.487		TMEM204	transmembrane protein 204
chr20_+_43104513	2.487	NM_001039199 NM_024331	TTPAL	tocopherol (alpha) transfer protein-like
chr11_-_31825593	2.486		PAX6	paired box 6
chr16_-_29757264	2.481	NM_175900	C16orf54	chromosome 16 open reading frame 54
chr6_-_154677868	2.470	NM_001130700 NM_015553	IPCEF1	interaction protein for cytohesin exchange factors 1
chr2_+_69001932	2.468	NM_001166276 NM_014882	ARHGAP25	Rho GTPase activating protein 25
chr13_+_46039024	2.466	NM_031431	COG3	component of oligomeric golgi complex 3
chr15_-_40599974	2.462		PLCB2	phospholipase C, beta 2
chr15_+_68924326	2.456	NM_001190457	CORO2B	coronin, actin binding protein, 2B
chr6_-_22297729	2.455	NM_000948	PRL	prolactin
chr14_+_63671101	2.445	NM_020663	RHOJ	ras homolog gene family, member J
chr12_-_6798619	2.444	NM_001039920 NM_001135734	ZNF384	zinc finger protein 384
chr9_-_21368005	2.441	NM_006900	IFNA1 IFNA13	interferon, alpha 1 interferon, alpha 13
chrX_-_50557019	2.436	NM_020717	SHROOM4	shroom family member 4
chr5_-_141993691	2.432	NM_033137	FGF1	fibroblast growth factor 1 (acidic)
chr1_+_40506449	2.429		CAP1	CAP, adenylate cyclase-associated protein 1 (yeast)
chr7_+_29234325	2.429		CHN2	chimerin (chimaerin) 2
chr1_-_156698188	2.428		ISG20L2	interferon stimulated exonuclease gene 20kDa-like 2
chr20_+_49126919	2.410		PTPN1	protein tyrosine phosphatase, non-receptor type 1
chr17_-_42466840	2.382	NM_000419	ITGA2B	integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)
chr7_+_100770378	2.379	NM_000602 NM_001165413	SERPINE1	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
chr6_-_11779279	2.363	NM_001143948 NM_032744	C6orf105	chromosome 6 open reading frame 105
chr2_-_27603249	2.362	NM_001201459	ZNF513	zinc finger protein 513
chrX_-_70331297	2.359	NM_000206	IL2RG	interleukin 2 receptor, gamma
chr11_-_102651321	2.353	NM_002425	MMP10	matrix metallopeptidase 10 (stromelysin 2)
chr7_-_45018559	2.351		MYO1G	myosin IG
chr2_-_238322770	2.346		COL6A3	collagen, type VI, alpha 3
chrY_+_2709630	2.345		RPS4Y1	ribosomal protein S4, Y-linked 1
chr15_-_40600065	2.344		PLCB2	phospholipase C, beta 2
chr3_+_111260925	2.339	NM_005816 NM_198196	CD96	CD96 molecule
chr12_-_6798528	2.327	NM_133476	ZNF384	zinc finger protein 384
chr1_+_209859524	2.326	NM_001206741 NM_181755	HSD11B1	hydroxysteroid (11-beta) dehydrogenase 1
chrY_+_2709596	2.326	NM_001008	RPS4Y1	ribosomal protein S4, Y-linked 1
chr11_-_125773086	2.322	NM_031307	PUS3	pseudouridylate synthase 3
chr15_-_41120905	2.317	NM_001130143 NM_017726	PPP1R14D	protein phosphatase 1, regulatory (inhibitor) subunit 14D
chr9_+_34458810	2.313	NM_012144	DNAI1	dynein, axonemal, intermediate chain 1
chr5_+_140625146	2.309	NM_018935	PCDHB15	protocadherin beta 15
chr3_-_50649080	2.302		CISH	cytokine inducible SH2-containing protein
chr19_-_36246206	2.299		HSPB6	heat shock protein, alpha-crystallin-related, B6
chr3_+_11267666	2.297	NM_001098211	HRH1	histamine receptor H1
chr11_+_67171379	2.296		TBC1D10C	TBC1 domain family, member 10C
chr10_-_28287790	2.292	NM_018076	ARMC4	armadillo repeat containing 4
chr17_-_9939873	2.289		GAS7	growth arrest-specific 7
chr22_-_17700265	2.288		CECR1	cat eye syndrome chromosome region, candidate 1
chr14_+_21249209	2.285	NM_005615	RNASE6	ribonuclease, RNase A family, k6
chr1_+_40506406	2.278		CAP1	CAP, adenylate cyclase-associated protein 1 (yeast)

Gene overrepresentation in process category:

Enrichment	P-value	GO Accession	GO Term
1.50	5.42e-09	GO:0023052	signaling
1.94	3.49e-08	GO:0002376	immune system process
1.73	4.59e-08	GO:0048583	regulation of response to stimulus
2.21	8.78e-07	GO:0002682	regulation of immune system process
2.14	1.61e-06	GO:0006955	immune response
1.30	2.51e-06	GO:0050896	response to stimulus
1.45	3.65e-06	GO:0007165	signal transduction
2.46	8.02e-06	GO:0050776	regulation of immune response
2.27	7.97e-05	GO:0001775	cell activation
1.94	1.13e-04	GO:0006952	defense response
2.33	1.19e-04	GO:0002684	positive regulation of immune system process
1.86	2.61e-04	GO:0009611	response to wounding
1.82	3.68e-04	GO:0042127	regulation of cell proliferation
1.56	4.79e-04	GO:0007166	cell surface receptor linked signaling pathway
3.66	1.60e-03	GO:0002768	immune response-regulating cell surface receptor signaling pathway
3.17	1.73e-03	GO:0002697	regulation of immune effector process
2.64	2.29e-03	GO:0045321	leukocyte activation
1.83	2.81e-03	GO:0048584	positive regulation of response to stimulus
2.84	2.85e-03	GO:0046649	lymphocyte activation
2.06	3.49e-03	GO:0008284	positive regulation of cell proliferation
1.30	4.39e-03	GO:0051716	cellular response to stimulus
3.70	5.19e-03	GO:0050851	antigen receptor-mediated signaling pathway
1.18	5.41e-03	GO:0065007	biological regulation
2.57	5.74e-03	GO:0002694	regulation of leukocyte activation
1.25	7.26e-03	GO:0032501	multicellular organismal process
2.77	1.10e-02	GO:0002764	immune response-regulating signaling pathway
2.84	1.17e-02	GO:0051251	positive regulation of lymphocyte activation
2.76	1.22e-02	GO:0002696	positive regulation of leukocyte activation
2.48	1.24e-02	GO:0050865	regulation of cell activation
2.71	1.63e-02	GO:0050867	positive regulation of cell activation
3.41	1.66e-02	GO:0002429	immune response-activating cell surface receptor signaling pathway
8.33	1.69e-02	GO:0045058	T cell selection
3.02	1.82e-02	GO:0050870	positive regulation of T cell activation
3.88	2.19e-02	GO:0050671	positive regulation of lymphocyte proliferation
2.54	2.31e-02	GO:0051249	regulation of lymphocyte activation
1.50	2.57e-02	GO:0023051	regulation of signaling
3.83	2.58e-02	GO:0032946	positive regulation of mononuclear cell proliferation
3.41	3.00e-02	GO:0030098	lymphocyte differentiation
3.78	3.03e-02	GO:0050852	T cell receptor signaling pathway
3.78	3.03e-02	GO:0070665	positive regulation of leukocyte proliferation
1.88	3.87e-02	GO:0050878	regulation of body fluid levels
1.18	4.04e-02	GO:0050789	regulation of biological process
2.68	4.60e-02	GO:0050863	regulation of T cell activation

Gene overrepresentation in compartment category:

Enrichment	P-value	GO Accession	GO Term
1.59	2.12e-17	GO:0071944	cell periphery
1.59	7.30e-17	GO:0005886	plasma membrane
1.58	5.91e-07	GO:0044459	plasma membrane part
1.78	1.96e-06	GO:0005887	integral to plasma membrane
1.77	2.64e-06	GO:0031226	intrinsic to plasma membrane
11.80	1.29e-04	GO:0042101	T cell receptor complex
1.19	2.68e-04	GO:0016020	membrane
1.42	4.38e-03	GO:0005576	extracellular region
1.20	5.50e-03	GO:0044425	membrane part
1.22	5.92e-03	GO:0031224	intrinsic to membrane
1.61	6.88e-03	GO:0044421	extracellular region part
2.72	3.11e-02	GO:0043235	receptor complex
1.63	3.97e-02	GO:0005615	extracellular space
1.20	4.91e-02	GO:0016021	integral to membrane

Gene overrepresentation in function category:

Enrichment	P-value	GO Accession	GO Term
1.67	1.41e-06	GO:0004872	receptor activity
1.58	2.19e-06	GO:0004871	signal transducer activity
1.58	2.19e-06	GO:0060089	molecular transducer activity
1.59	2.57e-03	GO:0004888	transmembrane receptor activity