Motif ID: EHF.p2

Z-value: 2.591


Transcription factors associated with EHF.p2:

Gene SymbolEntrez IDGene Name
EHF 26298 ets homologous factor

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
EHFhg19_v1_chr11_+_34642651_34642681-0.038.1e-01Click!


Activity profile for motif EHF.p2.

activity profile for motif EHF.p2


Sorted Z-values histogram for motif EHF.p2

Sorted Z-values for motif EHF.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of EHF.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chrX_+_30233674 46.657 NM_002364
MAGEB2
melanoma antigen family B, 2
chr13_-_114103452 40.624 NM_199162
ADPRHL1
ADP-ribosylhydrolase like 1
chr4_-_39033981 25.326 NM_024943
TMEM156
transmembrane protein 156
chr19_+_6772705 19.504 NM_005428
VAV1
vav 1 guanine nucleotide exchange factor
chrX_-_130964633 17.256 LOC286467
family with sequence similarity 195, member A pseudogene
chr19_+_6772801 14.240


chr6_-_7389941 14.074 NM_001170692
NM_001170693
NM_205864
CAGE1


cancer antigen 1


chr19_-_17516383 13.017 NM_004335
BST2
bone marrow stromal cell antigen 2
chr21_-_15918635 12.559 NM_022136
SAMSN1
SAM domain, SH3 domain and nuclear localization signals 1
chr17_-_19648771 11.363 NM_001135168
ALDH3A1
aldehyde dehydrogenase 3 family, member A1
chr19_+_10381763 11.096 ICAM1
intercellular adhesion molecule 1
chr10_+_114154522 10.500 ACSL5
acyl-CoA synthetase long-chain family member 5
chr19_+_1753661 9.218 NM_001080488
ONECUT3
one cut homeobox 3
chr19_-_56632644 9.140 NM_001002836
ZNF787
zinc finger protein 787
chr2_+_169659099 9.032 NM_001039724
NM_001171632
NM_052946
NOSTRIN


nitric oxide synthase trafficker


chr19_-_55791446 9.003 HSPBP1
HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
chr2_+_27994581 8.855 NM_004891
NM_145330
MRPL33

mitochondrial ribosomal protein L33

chr19_-_50083813 8.631 NOSIP
nitric oxide synthase interacting protein
chr13_+_31287614 8.604 NM_001204406
ALOX5AP
arachidonate 5-lipoxygenase-activating protein
chr19_-_50083791 8.479 NM_015953
NOSIP
nitric oxide synthase interacting protein
chr11_-_116658701 8.428 ZNF259
zinc finger protein 259
chr2_-_188419185 8.407 NM_001032281
NM_006287
TFPI

tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)

chr19_+_56186580 8.401 EPN1
epsin 1
chr19_-_55791490 8.200 HSPBP1
HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
chr19_+_56186569 8.041 EPN1
epsin 1
chr2_+_27994586 7.979 MRPL33
mitochondrial ribosomal protein L33
chr19_+_56186610 7.974 EPN1
epsin 1
chrX_-_153775774 7.962 NM_001042351
G6PD
glucose-6-phosphate dehydrogenase
chr19_-_56092184 7.961 NM_152600
ZNF579
zinc finger protein 579
chr22_-_43485333 7.866 NM_012263
TTLL1
tubulin tyrosine ligase-like family, member 1
chr19_-_50379833 7.767 AKT1S1
AKT1 substrate 1 (proline-rich)
chr19_-_55791428 7.699 HSPBP1
HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
chrX_-_153775427 7.687 G6PD
glucose-6-phosphate dehydrogenase
chr19_+_56186426 7.636 NM_001130072
NM_013333
EPN1

epsin 1

chr19_-_39368889 7.497 NM_001195833
NM_198445
RINL

Ras and Rab interactor-like

chr20_+_58630965 7.066 NM_173644
C20orf197
chromosome 20 open reading frame 197
chr19_-_59066458 6.852 CHMP2A
charged multivesicular body protein 2A
chr1_-_92949045 6.812 GFI1
growth factor independent 1 transcription repressor
chr11_-_116658738 6.685 NM_003904
ZNF259
zinc finger protein 259
chr1_-_204183036 6.512 NM_198447
GOLT1A
golgi transport 1A
chr6_-_11382501 6.484 NM_001142393
NEDD9
neural precursor cell expressed, developmentally down-regulated 9
chr3_-_185270258 6.441 NM_139248
LIPH
lipase, member H
chr7_-_151574209 6.421 NM_016203
PRKAG2
protein kinase, AMP-activated, gamma 2 non-catalytic subunit
chr19_-_59066477 6.404 NM_014453
CHMP2A
charged multivesicular body protein 2A
chr19_+_59070557 6.381 LOC100131691
uncharacterized LOC100131691
chr19_-_59070324 6.214 NM_003969
UBE2M
ubiquitin-conjugating enzyme E2M
chr19_-_59066372 6.201 CHMP2A
charged multivesicular body protein 2A
chr19_+_10381516 6.190 NM_000201
ICAM1
intercellular adhesion molecule 1
chr19_-_56632600 6.110 ZNF787
zinc finger protein 787
chr19_-_59066353 6.058 NM_198426
CHMP2A
charged multivesicular body protein 2A
chr19_+_56146358 6.039


chr19_+_48248792 5.995 NM_015710
GLTSCR2
glioma tumor suppressor candidate region gene 2
chr19_-_40791265 5.942 AKT2
v-akt murine thymoma viral oncogene homolog 2
chr19_-_59066303 5.914 CHMP2A
charged multivesicular body protein 2A
chr2_-_188419049 5.835 TFPI
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chr19_-_58662144 5.829 NM_024620
ZNF329
zinc finger protein 329
chr18_+_55888838 5.791 NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like
chr19_+_39936185 5.650 NM_001111020
NM_001130824
NM_001130825
SUPT5H


suppressor of Ty 5 homolog (S. cerevisiae)


chr19_+_53935243 5.585 LOC147804
ZNF761
tropomyosin 3 pseudogene
zinc finger protein 761
chr19_-_40791291 5.570 NM_001243027
NM_001243028
NM_001626
AKT2


v-akt murine thymoma viral oncogene homolog 2


chr1_-_149785235 5.539 NM_001123375
HIST2H3D
histone cluster 2, H3d
chr11_+_64107687 5.467 NM_032251
CCDC88B
coiled-coil domain containing 88B
chr1_+_156863522 5.464 NM_001080471
PEAR1
platelet endothelial aggregation receptor 1
chr19_+_34745452 5.451 NM_014686
KIAA0355
KIAA0355
chr19_-_55791727 5.422 NM_001130106
NM_012267
HSPBP1

HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1

chr19_+_48248798 5.389 GLTSCR2
glioma tumor suppressor candidate region gene 2
chr19_+_39936220 5.356 SUPT5H
suppressor of Ty 5 homolog (S. cerevisiae)
chr19_+_55897298 5.345 NM_000991
NM_001136134
NM_001136135
NM_001136136
NM_001136137
RPL28




ribosomal protein L28




chr10_+_114135965 5.333 ACSL5
acyl-CoA synthetase long-chain family member 5
chr1_-_92949355 5.315 NM_001127215
GFI1
growth factor independent 1 transcription repressor
chr5_-_150460550 5.278 TNIP1
TNFAIP3 interacting protein 1
chr1_+_18807423 5.273 NM_152375
KLHDC7A
kelch domain containing 7A
chr19_-_59069747 5.243 UBE2M
ubiquitin-conjugating enzyme E2M
chr19_-_49016418 5.171 NM_001080434
LMTK3
lemur tyrosine kinase 3
chr12_+_53693454 5.124 NM_021640
C12orf10
chromosome 12 open reading frame 10
chr10_+_114135937 5.114 NM_016234
ACSL5
acyl-CoA synthetase long-chain family member 5
chr2_+_202125222 5.108 NM_033356
CASP8
caspase 8, apoptosis-related cysteine peptidase
chr19_-_40791248 5.080 AKT2
v-akt murine thymoma viral oncogene homolog 2
chr2_+_85980600 5.041 NM_032827
ATOH8
atonal homolog 8 (Drosophila)
chr17_-_7166263 5.004 NM_001185023
NM_001307
CLDN7

claudin 7

chr15_+_101420004 4.995 NM_000693
ALDH1A3
aldehyde dehydrogenase 1 family, member A3
chr12_-_53343607 4.987 KRT8
keratin 8
chr19_+_53970988 4.959 NM_001004301
ZNF813
zinc finger protein 813
chr18_+_55888799 4.949 NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like
chr14_-_93673360 4.936 NM_032490
C14orf142
chromosome 14 open reading frame 142
chr17_-_8027396 4.863 NM_001165967
NM_032580
HES7

hairy and enhancer of split 7 (Drosophila)

chr7_+_93551015 4.862 NM_004126
GNG11
guanine nucleotide binding protein (G protein), gamma 11
chr16_+_30108398 4.841


chr19_-_40791224 4.829 AKT2
v-akt murine thymoma viral oncogene homolog 2
chr17_+_26711510 4.827 SARM1
sterile alpha and TIR motif containing 1
chr2_+_71162995 4.819 NM_001692
ATP6V1B1
ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1
chr12_+_104659046 4.817 RPL18A
ribosomal protein L18a
chr12_-_123201319 4.801 NM_006018
HCAR3
hydroxycarboxylic acid receptor 3
chr19_+_58962954 4.800 NM_207395
ZNF324B
zinc finger protein 324B
chr16_+_78133163 4.795 NM_016373
NM_130791
NM_130844
WWOX


WW domain containing oxidoreductase


chr1_-_92949500 4.769 GFI1
growth factor independent 1 transcription repressor
chrX_-_153775002 4.768 G6PD
glucose-6-phosphate dehydrogenase
chr18_+_55862577 4.765 NM_001144970
NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like
chr17_-_7165788 4.696 CLDN7
claudin 7
chr19_+_39936240 4.692 SUPT5H
suppressor of Ty 5 homolog (S. cerevisiae)
chr10_+_114206988 4.677 VTI1A
vesicle transport through interaction with t-SNAREs homolog 1A (yeast)
chr19_+_42363987 4.675 NM_001022
RPS19
ribosomal protein S19
chr19_+_58816714 4.671 ERVK3-1
endogenous retrovirus group K3, member 1
chr19_+_50168398 4.620 NM_001040668
NM_138639
BCL2L12

BCL2-like 12 (proline rich)

chr15_+_101420032 4.584 ALDH1A3
aldehyde dehydrogenase 1 family, member A3
chr20_-_30310597 4.546 NM_001191
NM_138578
BCL2L1

BCL2-like 1

chr10_+_35484829 4.507 NM_182721
NM_182722
NM_182723
NM_182724
NM_182725
CREM




cAMP responsive element modulator




chr19_+_41082980 4.499 SHKBP1
SH3KBP1 binding protein 1
chr16_-_72127767 4.484 NM_001142317
TXNL4B
thioredoxin-like 4B
chr22_-_50765405 4.459 NM_001001794
FAM116B
family with sequence similarity 116, member B
chr19_+_58898634 4.456 NM_001009
RPS5
ribosomal protein S5
chr9_+_97021556 4.410 NM_194320
ZNF169
zinc finger protein 169
chr19_+_53935240 4.409 LOC147804
tropomyosin 3 pseudogene
chr19_+_39936251 4.399 SUPT5H
suppressor of Ty 5 homolog (S. cerevisiae)
chr14_-_59951125 4.398


chr18_+_14179298 4.361 ANKRD20A5P
ankyrin repeat domain 20 family, member A5, pseudogene
chr19_+_6464259 4.351 NM_139161
NM_174881
CRB3

crumbs homolog 3 (Drosophila)

chr19_-_41220977 4.338 ADCK4
aarF domain containing kinase 4
chr19_+_39936275 4.322 NM_003169
SUPT5H
suppressor of Ty 5 homolog (S. cerevisiae)
chr8_+_182199 4.301 NM_173539
NM_001042415
NM_001042416
ZNF596


zinc finger protein 596


chr19_+_56166418 4.299 U2AF2
U2 small nuclear RNA auxiliary factor 2
chr19_+_54619114 4.283 PRPF31
PRP31 pre-mRNA processing factor 31 homolog (S. cerevisiae)
chr19_-_40791145 4.276 AKT2
v-akt murine thymoma viral oncogene homolog 2
chr3_+_183967414 4.263 NM_014693
NM_032331
ECE2

endothelin converting enzyme 2

chr19_+_58816757 4.254 ERVK3-1
endogenous retrovirus group K3, member 1
chr10_+_114206708 4.233 NM_145206
VTI1A
vesicle transport through interaction with t-SNAREs homolog 1A (yeast)
chr1_+_6086412 4.229 KCNAB2
potassium voltage-gated channel, shaker-related subfamily, beta member 2
chr19_+_46498338 4.209 NM_001080402
CCDC61
coiled-coil domain containing 61
chr19_-_41220992 4.205 NM_001142555
ADCK4
aarF domain containing kinase 4
chr6_-_28104553 4.164 LOC100129195
uncharacterized LOC100129195
chr12_-_49318663 4.153 NM_001143781
FKBP11
FK506 binding protein 11, 19 kDa
chr19_+_46498695 4.147 CCDC61
coiled-coil domain containing 61
chr2_+_44589042 4.120 NM_024766
CAMKMT
calmodulin-lysine N-methyltransferase
chr1_+_24742244 4.110 NM_020448
NIPAL3
NIPA-like domain containing 3
chr19_-_44439410 4.096 NM_003425
ZNF45
zinc finger protein 45
chr10_+_44101854 4.079 NM_145312
ZNF485
zinc finger protein 485
chr17_-_39093671 4.066 NM_015515
KRT23
keratin 23 (histone deacetylase inducible)
chr19_+_54619149 4.045 PRPF31
PRP31 pre-mRNA processing factor 31 homolog (S. cerevisiae)
chr10_-_12237840 4.028 NUDT5
nudix (nucleoside diphosphate linked moiety X)-type motif 5
chr16_-_30124829 4.016 NM_024307
GDPD3
glycerophosphodiester phosphodiesterase domain containing 3
chr7_+_75039632 4.014 NSUN5P1
NOP2/Sun domain family, member 5 pseudogene 1
chr19_+_53935222 4.012 NM_001008401
ZNF761
zinc finger protein 761
chr19_-_14682811 4.000 NM_004146
NDUFB7
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa
chrX_-_119694871 3.992 CUL4B
cullin 4B
chr16_+_2880172 3.969 NM_145252
ZG16B
zymogen granule protein 16 homolog B (rat)
chr10_-_81965113 3.967 ANXA11
annexin A11
chr12_-_63328663 3.967 NM_020700
PPM1H
protein phosphatase, Mg2+/Mn2+ dependent, 1H
chr19_+_49497122 3.959 NM_006666
RUVBL2
RuvB-like 2 (E. coli)
chr6_-_42946887 3.946 PEX6
peroxisomal biogenesis factor 6
chr19_+_41082792 3.946 SHKBP1
SH3KBP1 binding protein 1
chr11_+_65408191 3.946 SIPA1
signal-induced proliferation-associated 1
chr11_-_3186522 3.866 OSBPL5
oxysterol binding protein-like 5
chr18_+_20715726 3.846 NM_001100619
CABLES1
Cdk5 and Abl enzyme substrate 1
chr19_-_46366337 3.815 NM_004819
SYMPK
symplekin
chr17_+_80186281 3.808 NM_001042422
NM_001206950
SLC16A3

solute carrier family 16, member 3 (monocarboxylic acid transporter 4)

chr19_+_44669214 3.802 NM_001146220
NM_001032373
NM_001032374
NM_015919
NM_001032372
ZNF226




zinc finger protein 226




chr19_+_41082786 3.795 SHKBP1
SH3KBP1 binding protein 1
chr4_+_41937368 3.788 TMEM33
transmembrane protein 33
chr1_+_206643830 3.784 IKBKE
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
chr19_-_56110851 3.783 NM_032836
FIZ1
FLT3-interacting zinc finger 1
chr19_+_41082729 3.782 NM_138392
SHKBP1
SH3KBP1 binding protein 1
chr5_+_133861685 3.767 NM_015288
PHF15
PHD finger protein 15
chr15_-_91565685 3.755 NM_018668
VPS33B
vacuolar protein sorting 33 homolog B (yeast)
chrX_-_119694719 3.690 NM_001079872
CUL4B
cullin 4B
chr11_-_3186507 3.689 OSBPL5
oxysterol binding protein-like 5
chr6_-_49430851 3.685 NM_000255
MUT
methylmalonyl CoA mutase
chr11_-_3186475 3.676 OSBPL5
oxysterol binding protein-like 5
chr10_-_12238053 3.671 NM_014142
NUDT5
nudix (nucleoside diphosphate linked moiety X)-type motif 5
chr6_-_32143886 3.658 AGPAT1
1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha)
chr19_-_11616395 3.649 ZNF653
zinc finger protein 653
chr11_+_1855673 3.648 NM_138567
SYT8
synaptotagmin VIII
chr12_+_53443834 3.647 NM_170754
TENC1
tensin like C1 domain containing phosphatase (tensin 2)
chr19_-_54619025 3.623 NM_013342
TFPT
TCF3 (E2A) fusion partner (in childhood Leukemia)
chr19_+_55897302 3.615 RPL28
ribosomal protein L28
chr6_-_41254392 3.609 NM_001242589
NM_001242590
NM_018643
TREM1


triggering receptor expressed on myeloid cells 1


chr6_-_44233244 3.600 NFKBIE
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
chr19_+_58978637 3.579 ZNF324
zinc finger protein 324
chr6_-_32143795 3.579 AGPAT1
1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha)
chr18_+_55711746 3.577 NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like
chr4_+_41937105 3.569 NM_018126
TMEM33
transmembrane protein 33
chr14_-_73493744 3.569 NM_021260
ZFYVE1
zinc finger, FYVE domain containing 1
chr19_+_54618789 3.557 NM_015629
PRPF31
PRP31 pre-mRNA processing factor 31 homolog (S. cerevisiae)
chr16_-_87799540 3.552 NM_001184854
NM_001184856
NM_017566
KLHDC4


kelch domain containing 4


chr1_+_204485461 3.535 NM_001204171
NM_001204172
NM_002393
MDM4


Mdm4 p53 binding protein homolog (mouse)


chr5_+_132202315 3.533 NM_014402
UQCRQ
ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa
chr20_+_19998008 3.530 NAA20
N(alpha)-acetyltransferase 20, NatB catalytic subunit
chr1_-_153919140 3.517 NM_014856
DENND4B
DENN/MADD domain containing 4B
chr1_+_6086369 3.510 KCNAB2
potassium voltage-gated channel, shaker-related subfamily, beta member 2
chr11_+_68115423 3.509 LRP5
low density lipoprotein receptor-related protein 5
chr19_+_54641475 3.506 CNOT3
CCR4-NOT transcription complex, subunit 3
chr22_-_50968475 3.503 NM_001113755
NM_001953
TYMP

thymidine phosphorylase

chr19_+_42364262 3.495 RPS19
ribosomal protein S19
chr19_+_53898383 3.495 NM_001040185
ZNF765
zinc finger protein 765
chr19_+_53898417 3.494 ZNF765
zinc finger protein 765
chr19_-_46195171 3.484 SNRPD2
small nuclear ribonucleoprotein D2 polypeptide 16.5kDa
chr1_-_111506494 3.470 NM_001006945
NM_018372
LRIF1

ligand dependent nuclear receptor interacting factor 1

chr17_-_56065474 3.470 VEZF1
vascular endothelial zinc finger 1
chr17_-_71088832 3.467 NM_001159770
NM_139177
SLC39A11

solute carrier family 39 (metal ion transporter), member 11

chr19_+_54641420 3.437 NM_014516
CNOT3
CCR4-NOT transcription complex, subunit 3
chr17_-_76975932 3.434 NM_005567
LGALS3BP
lectin, galactoside-binding, soluble, 3 binding protein

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
3.11 4.34e-13 GO:0006412 translation
1.30 1.68e-10 GO:0044237 cellular metabolic process
2.46 1.26e-08 GO:0016032 viral reproduction
1.51 2.02e-08 GO:0044267 cellular protein metabolic process
1.64 6.18e-08 GO:0034645 cellular macromolecule biosynthetic process
1.24 7.67e-08 GO:0008152 metabolic process
1.34 8.17e-08 GO:0044260 cellular macromolecule metabolic process
1.63 9.04e-08 GO:0009059 macromolecule biosynthetic process
1.49 3.85e-07 GO:0044249 cellular biosynthetic process
1.55 1.33e-06 GO:0010467 gene expression
1.46 1.89e-06 GO:0009058 biosynthetic process
3.43 3.77e-06 GO:0045333 cellular respiration
2.26 6.78e-06 GO:0006091 generation of precursor metabolites and energy
1.23 1.13e-05 GO:0044238 primary metabolic process
1.41 1.20e-05 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.84 1.29e-05 GO:0046907 intracellular transport
2.51 1.46e-05 GO:0015980 energy derivation by oxidation of organic compounds
1.27 1.95e-05 GO:0043170 macromolecule metabolic process
1.37 4.23e-05 GO:0019538 protein metabolic process
1.75 8.98e-05 GO:0015031 protein transport
1.50 9.99e-05 GO:0016070 RNA metabolic process
3.07 1.06e-04 GO:0007005 mitochondrion organization
2.41 1.08e-04 GO:0034660 ncRNA metabolic process
1.74 1.12e-04 GO:0045184 establishment of protein localization
1.43 1.23e-04 GO:0090304 nucleic acid metabolic process
3.66 3.08e-04 GO:0031145 anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
3.96 3.19e-04 GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
3.57 4.86e-04 GO:0051351 positive regulation of ligase activity
1.33 5.18e-04 GO:0034641 cellular nitrogen compound metabolic process
1.62 5.50e-04 GO:0008104 protein localization
3.79 6.81e-04 GO:0051352 negative regulation of ligase activity
3.79 6.81e-04 GO:0051444 negative regulation of ubiquitin-protein ligase activity
2.94 7.31e-04 GO:0022900 electron transport chain
3.63 7.33e-04 GO:0051439 regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
3.74 8.67e-04 GO:0051437 positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
3.58 9.20e-04 GO:0051443 positive regulation of ubiquitin-protein ligase activity
3.34 9.21e-04 GO:0022904 respiratory electron transport chain
3.27 1.37e-03 GO:0051340 regulation of ligase activity
3.89 1.88e-03 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
3.89 1.88e-03 GO:0072395 signal transduction involved in cell cycle checkpoint
3.89 1.88e-03 GO:0072401 signal transduction involved in DNA integrity checkpoint
3.89 1.88e-03 GO:0072404 signal transduction involved in G1/S transition checkpoint
3.89 1.88e-03 GO:0072413 signal transduction involved in mitotic cell cycle checkpoint
3.89 1.88e-03 GO:0072422 signal transduction involved in DNA damage checkpoint
3.89 1.88e-03 GO:0072431 signal transduction involved in mitotic cell cycle G1/S transition DNA damage checkpoint
3.89 1.88e-03 GO:0072474 signal transduction involved in mitotic cell cycle G1/S checkpoint
3.70 2.08e-03 GO:0031571 mitotic cell cycle G1/S transition DNA damage checkpoint
1.30 2.15e-03 GO:0006807 nitrogen compound metabolic process
3.40 2.18e-03 GO:2000045 regulation of G1/S transition of mitotic cell cycle
3.26 2.59e-03 GO:0051438 regulation of ubiquitin-protein ligase activity
2.63 3.30e-03 GO:0010498 proteasomal protein catabolic process
2.63 3.30e-03 GO:0043161 proteasomal ubiquitin-dependent protein catabolic process
3.44 3.35e-03 GO:0006839 mitochondrial transport
3.71 3.93e-03 GO:0071158 positive regulation of cell cycle arrest
4.34 4.07e-03 GO:0006418 tRNA aminoacylation for protein translation
4.34 4.07e-03 GO:0043038 amino acid activation
4.34 4.07e-03 GO:0043039 tRNA aminoacylation
3.40 4.14e-03 GO:0031575 mitotic cell cycle G1/S transition checkpoint
3.40 4.14e-03 GO:0071779 G1/S transition checkpoint
2.73 5.49e-03 GO:0010565 regulation of cellular ketone metabolic process
3.21 5.91e-03 GO:0031397 negative regulation of protein ubiquitination
3.95 6.67e-03 GO:0006521 regulation of cellular amino acid metabolic process
1.51 6.79e-03 GO:0051641 cellular localization
3.54 7.82e-03 GO:0072594 establishment of protein localization to organelle
2.34 9.64e-03 GO:0071843 cellular component biogenesis at cellular level
1.49 9.76e-03 GO:0033036 macromolecule localization
1.53 9.79e-03 GO:0051649 establishment of localization in cell
2.03 1.02e-02 GO:0051603 proteolysis involved in cellular protein catabolic process
1.88 1.12e-02 GO:0044262 cellular carbohydrate metabolic process
2.82 1.18e-02 GO:0006399 tRNA metabolic process
2.29 1.50e-02 GO:0033365 protein localization to organelle
2.70 1.58e-02 GO:0007093 mitotic cell cycle checkpoint
2.84 1.60e-02 GO:0031398 positive regulation of protein ubiquitination
1.99 1.69e-02 GO:0044257 cellular protein catabolic process
3.08 1.94e-02 GO:0018196 peptidyl-asparagine modification
3.08 1.94e-02 GO:0018279 protein N-linked glycosylation via asparagine
3.08 1.94e-02 GO:0030330 DNA damage response, signal transduction by p53 class mediator
1.79 2.08e-02 GO:0034613 cellular protein localization
2.31 2.31e-02 GO:0022613 ribonucleoprotein complex biogenesis
1.77 2.53e-02 GO:0070727 cellular macromolecule localization
1.89 3.04e-02 GO:0006886 intracellular protein transport
2.43 3.37e-02 GO:0031400 negative regulation of protein modification process
1.91 4.45e-02 GO:0030163 protein catabolic process
2.74 4.64e-02 GO:0042770 signal transduction in response to DNA damage

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
1.32 2.26e-27 GO:0043227 membrane-bounded organelle
1.32 2.92e-27 GO:0043231 intracellular membrane-bounded organelle
1.22 2.49e-25 GO:0044424 intracellular part
1.21 7.24e-25 GO:0005622 intracellular
1.26 6.34e-22 GO:0043229 intracellular organelle
1.26 1.27e-21 GO:0043226 organelle
2.06 3.44e-19 GO:0005739 mitochondrion
2.39 3.14e-15 GO:0044429 mitochondrial part
1.33 9.45e-14 GO:0044444 cytoplasmic part
2.44 8.72e-11 GO:0005740 mitochondrial envelope
1.22 1.53e-10 GO:0005737 cytoplasm
2.45 2.07e-10 GO:0031966 mitochondrial membrane
1.55 3.99e-09 GO:0031090 organelle membrane
2.03 7.08e-09 GO:0031967 organelle envelope
1.29 8.19e-09 GO:0044446 intracellular organelle part
1.99 1.97e-08 GO:0031975 envelope
1.28 2.57e-08 GO:0044422 organelle part
1.25 1.49e-06 GO:0005634 nucleus
2.39 2.30e-06 GO:0005743 mitochondrial inner membrane
2.28 6.43e-06 GO:0019866 organelle inner membrane
1.97 2.06e-05 GO:0030529 ribonucleoprotein complex
2.68 3.03e-05 GO:0005840 ribosome
3.99 1.10e-04 GO:0000502 proteasome complex
3.89 3.47e-04 GO:0015934 large ribosomal subunit
1.29 3.73e-04 GO:0032991 macromolecular complex
1.05 1.40e-03 GO:0044464 cell part
1.05 1.44e-03 GO:0005623 cell
2.79 1.61e-03 GO:0044455 mitochondrial membrane part
1.33 3.09e-03 GO:0031974 membrane-enclosed lumen
2.07 8.96e-03 GO:0005759 mitochondrial matrix
2.79 1.00e-02 GO:0005741 mitochondrial outer membrane
4.27 1.16e-02 GO:0005758 mitochondrial intermembrane space
1.33 1.51e-02 GO:0005829 cytosol
1.30 2.47e-02 GO:0070013 intracellular organelle lumen
3.84 3.41e-02 GO:0031970 organelle envelope lumen
1.98 3.65e-02 GO:0010008 endosome membrane
1.96 4.30e-02 GO:0044440 endosomal part
2.44 4.94e-02 GO:0031968 organelle outer membrane

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
3.13 1.94e-06 GO:0003735 structural constituent of ribosome
1.23 7.07e-05 GO:0003824 catalytic activity
1.30 2.97e-04 GO:0003676 nucleic acid binding
3.17 6.53e-04 GO:0015078 hydrogen ion transmembrane transporter activity
4.44 8.07e-04 GO:0004812 aminoacyl-tRNA ligase activity
4.44 8.07e-04 GO:0016875 ligase activity, forming carbon-oxygen bonds
4.44 8.07e-04 GO:0016876 ligase activity, forming aminoacyl-tRNA and related compounds
5.82 1.62e-03 GO:0004129 cytochrome-c oxidase activity
5.82 1.62e-03 GO:0015002 heme-copper terminal oxidase activity
5.82 1.62e-03 GO:0016675 oxidoreductase activity, acting on a heme group of donors
5.82 1.62e-03 GO:0016676 oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
11.63 6.31e-03 GO:0016417 S-acyltransferase activity
1.08 1.10e-02 GO:0005488 binding
1.54 2.53e-02 GO:0003723 RNA binding
1.38 3.06e-02 GO:0032559 adenyl ribonucleotide binding
1.38 3.28e-02 GO:0005524 ATP binding
1.35 3.48e-02 GO:0016740 transferase activity
1.37 3.99e-02 GO:0030554 adenyl nucleotide binding