Motif ID: EGR1..3.p2

Z-value: 1.674


Transcription factors associated with EGR1..3.p2:

Gene SymbolEntrez IDGene Name
EGR1 1958 early growth response 1
EGR2 1959 early growth response 2 (Krox-20 homolog, Drosophila)
EGR3 1960 early growth response 3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
EGR3hg19_v1_chr8_-_22550057_225500920.262.6e-02Click!
EGR1hg19_v1_chr5_+_137801178_137801450-0.132.7e-01Click!
EGR2hg19_v1_chr10_-_64576074_64576121-0.028.6e-01Click!


Activity profile for motif EGR1..3.p2.

activity profile for motif EGR1..3.p2


Sorted Z-values histogram for motif EGR1..3.p2

Sorted Z-values for motif EGR1..3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of EGR1..3.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr20_-_62462568 12.410 ZBTB46
zinc finger and BTB domain containing 46
chr1_-_9189087 10.054 NM_024980
GPR157
G protein-coupled receptor 157
chr6_+_126070813 7.784 HEY2
hairy/enhancer-of-split related with YRPW motif 2
chr17_+_56065408 7.553


chr19_+_8429010 7.491 NM_001039667
NM_139314
ANGPTL4

angiopoietin-like 4

chr11_+_129245834 7.385 NM_003658
BARX2
BARX homeobox 2
chr10_-_103535656 7.326 NM_006119
NM_033163
NM_033164
NM_033165
FGF8



fibroblast growth factor 8 (androgen-induced)



chr2_+_241375207 7.298 GPC1
glypican 1
chr12_-_28122884 6.992 NM_198964
NM_198966
PTHLH

parathyroid hormone-like hormone

chr8_-_143695812 6.580 NM_015193
ARC
activity-regulated cytoskeleton-associated protein
chr19_-_1863425 6.395 KLF16
Kruppel-like factor 16
chr3_-_39195101 5.941 NM_033027
CSRNP1
cysteine-serine-rich nuclear protein 1
chr19_+_1249882 5.854 MIDN
midnolin
chr12_+_57482886 5.799 NAB2
NGFI-A binding protein 2 (EGR1 binding protein 2)
chr2_-_46384 5.477 NM_001077710
FAM110C
family with sequence similarity 110, member C
chr7_-_559030 5.464 PDGFA
platelet-derived growth factor alpha polypeptide
chr3_-_39195034 5.419 CSRNP1
cysteine-serine-rich nuclear protein 1
chr6_+_37137882 5.409 NM_001243186
NM_002648
PIM1

pim-1 oncogene

chr6_+_126070895 5.361 HEY2
hairy/enhancer-of-split related with YRPW motif 2
chrX_+_9432980 5.172 NM_005647
TBL1X
transducin (beta)-like 1X-linked
chr11_-_65667858 4.960 FOSL1
FOS-like antigen 1
chr12_+_57482674 4.811 NM_005967
NAB2
NGFI-A binding protein 2 (EGR1 binding protein 2)
chr13_-_20767100 4.797 NM_004004
GJB2
gap junction protein, beta 2, 26kDa
chr12_+_57482922 4.744 NAB2
NGFI-A binding protein 2 (EGR1 binding protein 2)
chr13_-_20767036 4.720 GJB2
gap junction protein, beta 2, 26kDa
chr11_-_65667860 4.696 NM_005438
FOSL1
FOS-like antigen 1
chr19_+_16435734 4.677 KLF2
Kruppel-like factor 2 (lung)
chr16_-_402617 4.674 NM_003502
NM_181050
AXIN1

axin 1

chr19_-_51568323 4.610 NM_015596
KLK13
kallikrein-related peptidase 13
chr1_+_6673744 4.592 NM_153812
PHF13
PHD finger protein 13
chr12_-_120806893 4.518 NM_002442
MSI1
musashi homolog 1 (Drosophila)
chr11_-_65667809 4.512 FOSL1
FOS-like antigen 1
chr3_-_52090090 4.491 NM_001947
DUSP7
dual specificity phosphatase 7
chr16_-_28074776 4.456 NM_001109763
GSG1L
GSG1-like
chr1_-_19282773 4.326 NM_001136265
IFFO2
intermediate filament family orphan 2
chr8_-_103666018 4.319 NM_001032282
KLF10
Kruppel-like factor 10
chr12_+_130822590 4.181 PIWIL1
piwi-like 1 (Drosophila)
chr2_+_105471745 4.151 NM_006236
POU3F3
POU class 3 homeobox 3
chr3_+_11196213 4.124 NM_001098212
HRH1
histamine receptor H1
chr6_+_126070738 4.070 HEY2
hairy/enhancer-of-split related with YRPW motif 2
chr10_-_108924287 3.965 NM_001013031
NM_001206569
NM_001206570
NM_001206571
NM_001206572
NM_052918
SORCS1





sortilin-related VPS10 domain containing receptor 1





chr1_-_38471170 3.918 NM_001243878
NM_004468
FHL3

four and a half LIM domains 3

chr15_+_32322690 3.855 NM_000746
NM_001190455
CHRNA7

cholinergic receptor, nicotinic, alpha 7

chr19_-_1567875 3.848 NM_001174118
NM_203304
MEX3D

mex-3 homolog D (C. elegans)

chr19_-_40931880 3.844 NM_013376
SERTAD1
SERTA domain containing 1
chr15_-_76352068 3.837 NRG4
neuregulin 4
chr10_+_5566923 3.822 NM_005185
CALML3
calmodulin-like 3
chr7_-_106301329 3.748 NM_175884
C7orf74
chromosome 7 open reading frame 74
chr19_+_16435632 3.744 NM_016270
KLF2
Kruppel-like factor 2 (lung)
chr1_-_99470177 3.729 NM_001010861
NM_001037317
LPPR5

lipid phosphate phosphatase-related protein type 5

chr7_-_44365019 3.704 NM_001220
NM_172078
NM_172079
NM_172080
NM_172081
NM_172082
NM_172083
NM_172084
CAMK2B







calcium/calmodulin-dependent protein kinase II beta







chr1_+_15250578 3.685 NM_001018000
KAZN
kazrin, periplakin interacting protein
chr19_-_10047014 3.672 NM_058164
OLFM2
olfactomedin 2
chr4_+_1005609 3.560 NM_001004356
NM_001004358
FGFRL1

fibroblast growth factor receptor-like 1

chr17_-_43394326 3.548 NM_003954
MAP3K14
mitogen-activated protein kinase kinase kinase 14
chrX_-_17879355 3.524 NM_001172732
NM_001172739
NM_001172743
NM_021785
RAI2



retinoic acid induced 2



chr14_-_38064440 3.504 NM_004496
FOXA1
forkhead box A1
chr19_-_1237840 3.462 NM_152769
C19orf26
chromosome 19 open reading frame 26
chr17_+_81037504 3.433 NM_001004431
METRNL
meteorin, glial cell differentiation regulator-like
chrX_-_152939256 3.410 PNCK
pregnancy up-regulated non-ubiquitously expressed CaM kinase
chr22_+_39853316 3.408 NM_002409
MGAT3
mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
chr8_-_22550057 3.392 NM_001199881
EGR3
early growth response 3
chr1_-_223537400 3.374 NM_001037175
NM_017982
SUSD4

sushi domain containing 4

chr6_+_126070724 3.369 NM_012259
HEY2
hairy/enhancer-of-split related with YRPW motif 2
chr2_-_204399906 3.340 NM_203365
NM_213589
RAPH1

Ras association (RalGDS/AF-6) and pleckstrin homology domains 1

chr10_+_129705299 3.339 NM_006504
PTPRE
protein tyrosine phosphatase, receptor type, E
chr17_+_30813928 3.316 NM_003885
CDK5R1
cyclin-dependent kinase 5, regulatory subunit 1 (p35)
chr7_+_55955129 3.290 ZNF713
zinc finger protein 713
chr11_-_67141008 3.289 NM_013246
CLCF1
cardiotrophin-like cytokine factor 1
chr16_+_69139466 3.288 NM_001199280
HAS3
hyaluronan synthase 3
chr10_+_122216465 3.282 NM_001030059
PPAPDC1A
phosphatidic acid phosphatase type 2 domain containing 1A
chr3_-_171177851 3.266 NM_001161560
NM_001161561
NM_001161562
NM_001161563
NM_001161564
NM_001161565
NM_001161566
NM_015028
TNIK







TRAF2 and NCK interacting kinase







chr18_-_45935627 3.257 ZBTB7C
zinc finger and BTB domain containing 7C
chr5_+_7396030 3.252 NM_020546
ADCY2
adenylate cyclase 2 (brain)
chr18_+_12947972 3.247 NM_001013437
NM_031216
SEH1L

SEH1-like (S. cerevisiae)

chr9_+_17578952 3.227 NM_003026
SH3GL2
SH3-domain GRB2-like 2
chr11_-_64545933 3.215 NM_001178030
SF1
splicing factor 1
chr10_+_129705359 3.177 PTPRE
protein tyrosine phosphatase, receptor type, E
chr19_-_4065467 3.171 ZBTB7A
zinc finger and BTB domain containing 7A
chr16_+_84853585 3.169 NM_031476
CRISPLD2
cysteine-rich secretory protein LCCL domain containing 2
chr14_-_53417636 3.165 FERMT2
fermitin family member 2
chr16_+_1203240 3.164 NM_001005407
NM_021098
CACNA1H

calcium channel, voltage-dependent, T type, alpha 1H subunit

chr15_-_74726000 3.151 NM_001146030
SEMA7A
semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
chr20_+_49348050 3.142 NM_032521
PARD6B
par-6 partitioning defective 6 homolog beta (C. elegans)
chr22_+_39853534 3.085 MGAT3
mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
chr18_+_8609670 3.085


chr7_-_82073020 3.073 NM_000722
CACNA2D1
calcium channel, voltage-dependent, alpha 2/delta subunit 1
chr18_+_8609407 3.055 NM_001025300
RAB12
RAB12, member RAS oncogene family
chr18_+_12948004 3.054 SEH1L
SEH1-like (S. cerevisiae)
chr5_-_134914447 3.008 CXCL14
chemokine (C-X-C motif) ligand 14
chr1_+_210406194 3.005 NM_019605
SERTAD4
SERTA domain containing 4
chr15_+_40733302 2.988 NM_014952
BAHD1
bromo adjacent homology domain containing 1
chr5_-_72743829 2.986 FOXD1
forkhead box D1
chr8_-_22549901 2.984 NM_001199880
EGR3
early growth response 3
chr10_-_77161136 2.966 ZNF503
zinc finger protein 503
chr1_+_6484816 2.966 NM_031475
ESPN
espin
chr11_-_67141647 2.956 NM_001166212
CLCF1
cardiotrophin-like cytokine factor 1
chr11_-_64545988 2.949 SF1
splicing factor 1
chr10_+_134000335 2.938 NM_006426
DPYSL4
dihydropyrimidinase-like 4
chrX_+_152770083 2.922 BGN
biglycan
chr7_-_559479 2.919 NM_002607
NM_033023
PDGFA

platelet-derived growth factor alpha polypeptide

chr10_-_77159851 2.894 ZNF503
zinc finger protein 503
chr1_-_115212628 2.836 NM_198459
DENND2C
DENN/MADD domain containing 2C
chr4_-_819879 2.819 NM_006651
CPLX1
complexin 1
chr15_+_25093355 2.815


chr14_-_53417808 2.813 NM_001134999
NM_001135000
NM_006832
FERMT2


fermitin family member 2


chr4_+_1005395 2.806 FGFRL1
fibroblast growth factor receptor-like 1
chr1_-_166135978 2.737


chr1_+_15736422 2.734 EFHD2
EF-hand domain family, member D2
chr16_-_17564737 2.731 NM_022166
XYLT1
xylosyltransferase I
chr16_+_69141442 2.723 NM_005329
HAS3
hyaluronan synthase 3
chr17_+_77751929 2.723 NM_005189
NM_032647
CBX2

chromobox homolog 2

chr7_-_82072804 2.721 CACNA2D1
calcium channel, voltage-dependent, alpha 2/delta subunit 1
chr19_-_42759279 2.720 NM_006494
ERF
Ets2 repressor factor
chr3_+_170075449 2.706 NM_001145098
NM_005414
SKIL

SKI-like oncogene

chr16_+_27325244 2.695 NM_000418
NM_001008699
IL4R

interleukin 4 receptor

chr7_-_32931409 2.679 NM_015483
KBTBD2
kelch repeat and BTB (POZ) domain containing 2
chr21_+_45875368 2.674 NM_030891
LRRC3
leucine rich repeat containing 3
chr12_-_76425207 2.672 PHLDA1
pleckstrin homology-like domain, family A, member 1
chrX_+_152760346 2.666 NM_001711
BGN
biglycan
chr15_-_83953465 2.664 NM_001717
BNC1
basonuclin 1
chr4_+_7194317 2.599 NM_020777
SORCS2
sortilin-related VPS10 domain containing receptor 2
chr7_-_32931363 2.596 KBTBD2
kelch repeat and BTB (POZ) domain containing 2
chrX_-_19905449 2.584 SH3KBP1
SH3-domain kinase binding protein 1
chr16_+_25703346 2.583 NM_006040
HS3ST4
heparan sulfate (glucosamine) 3-O-sulfotransferase 4
chr1_-_1475739 2.577 NM_001114748
TMEM240
transmembrane protein 240
chr12_-_109125254 2.565 CORO1C
coronin, actin binding protein, 1C
chr17_-_78450247 2.564 NM_002522
NPTX1
neuronal pentraxin I
chr12_+_130822432 2.563 NM_001190971
NM_004764
PIWIL1

piwi-like 1 (Drosophila)

chr5_-_72744351 2.558 NM_004472
FOXD1
forkhead box D1
chr15_+_31619043 2.554 NM_015995
KLF13
Kruppel-like factor 13
chr11_-_64545864 2.530 SF1
splicing factor 1
chr16_+_27325269 2.527 IL4R
interleukin 4 receptor
chr17_+_38474513 2.500 RARA
retinoic acid receptor, alpha
chr3_-_45267804 2.482 NM_015444
TMEM158
transmembrane protein 158 (gene/pseudogene)
chrX_-_47479229 2.462 NM_006950
NM_133499
SYN1

synapsin I

chr19_+_51815095 2.449 NM_001101372
IGLON5
IgLON family member 5
chr7_-_130418859 2.431 NM_138693
KLF14
Kruppel-like factor 14
chr5_-_176037091 2.425 NM_052899
GPRIN1
G protein regulated inducer of neurite outgrowth 1
chr3_-_50649080 2.408 CISH
cytokine inducible SH2-containing protein
chr9_-_138798957 2.406 NM_015447
CAMSAP1
calmodulin regulated spectrin-associated protein 1
chr17_+_38474472 2.405 NM_001145301
NM_001145302
RARA

retinoic acid receptor, alpha

chr1_-_38273823 2.384 YRDC
yrdC domain containing (E. coli)
chr11_-_70963619 2.374 SHANK2
SH3 and multiple ankyrin repeat domains 2
chr6_+_1611544 2.369 FOXC1
forkhead box C1
chr22_+_41777932 2.369 NM_003216
TEF
thyrotrophic embryonic factor
chr8_-_8175860 2.360 SGK223
homolog of rat pragma of Rnd2
chr17_+_38474544 2.358 RARA
retinoic acid receptor, alpha
chr22_+_38035694 2.346 SH3BP1
SH3-domain binding protein 1
chr19_-_4066739 2.341 NM_015898
ZBTB7A
zinc finger and BTB domain containing 7A
chr12_+_111843743 2.337 NM_005475
SH2B3
SH2B adaptor protein 3
chr1_+_39456887 2.313 NM_001136275
NM_024595
AKIRIN1

akirin 1

chr4_-_6202251 2.306 NM_001099433
NM_144720
JAKMIP1

janus kinase and microtubule interacting protein 1

chr18_+_31158540 2.305 NM_030632
ASXL3
additional sex combs like 3 (Drosophila)
chr16_-_402398 2.289 AXIN1
axin 1
chr3_-_50649110 2.275 NM_013324
NM_145071
CISH

cytokine inducible SH2-containing protein

chr14_-_38064176 2.275 FOXA1
forkhead box A1
chr17_+_30593194 2.269 NM_138328
RHBDL3
rhomboid, veinlet-like 3 (Drosophila)
chr19_-_1863546 2.268 NM_031918
KLF16
Kruppel-like factor 16
chr19_-_42759151 2.261 ERF
Ets2 repressor factor
chr18_+_43913906 2.260 RNF165
ring finger protein 165
chr19_+_1753661 2.256 NM_001080488
ONECUT3
one cut homeobox 3
chr11_-_94964209 2.255 NM_144665
SESN3
sestrin 3
chr20_-_4229519 2.252 NM_000678
ADRA1D
adrenergic, alpha-1D-, receptor
chr8_-_144241918 2.251 NM_001130478
LY6H
lymphocyte antigen 6 complex, locus H
chr12_-_96793797 2.241 CDK17
cyclin-dependent kinase 17
chr10_-_77160650 2.240 ZNF503
zinc finger protein 503
chr2_-_70781146 2.230 NM_001099691
NM_003236
TGFA

transforming growth factor, alpha

chr20_-_50159037 2.228 NFATC2
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
chr15_-_74726258 2.223 NM_001146029
NM_003612
SEMA7A

semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)

chr18_-_31158150 2.217


chr17_-_882905 2.209 NM_022463
NXN
nucleoredoxin
chr15_+_73976537 2.205


chr4_-_38666429 2.202 FLJ13197
uncharacterized FLJ13197
chr5_-_176924601 2.201 NM_005451
NM_203352
NM_213636
PDLIM7


PDZ and LIM domain 7 (enigma)


chr18_+_12948010 2.196 SEH1L
SEH1-like (S. cerevisiae)
chr14_-_71275732 2.192 NM_033141
MAP3K9
mitogen-activated protein kinase kinase kinase 9
chr1_-_38273846 2.181 YRDC
yrdC domain containing (E. coli)
chr14_-_38064299 2.167 FOXA1
forkhead box A1
chr6_+_30130982 2.142 NM_033229
TRIM15
tripartite motif containing 15
chr12_-_51477138 2.140 CSRNP2
cysteine-serine-rich nuclear protein 2
chr19_+_1285766 2.136 NM_001405
EFNA2
ephrin-A2
chr7_+_45614179 2.135 ADCY1
adenylate cyclase 1 (brain)
chr17_-_79876027 2.129 SIRT7
sirtuin 7
chr12_-_76425375 2.127 NM_007350
PHLDA1
pleckstrin homology-like domain, family A, member 1
chr10_+_119302709 2.121


chr11_+_107799134 2.115 NM_017516
RAB39A
RAB39A, member RAS oncogene family
chr20_+_20348744 2.114 NM_002196
INSM1
insulinoma-associated 1
chr8_-_143867931 2.112 NM_003695
LY6D
lymphocyte antigen 6 complex, locus D
chr8_-_141645603 2.104 NM_001164623
NM_012154
EIF2C2

eukaryotic translation initiation factor 2C, 2

chr11_+_119076974 2.100 NM_005188
CBL
Cas-Br-M (murine) ecotropic retroviral transforming sequence
chr6_+_83073501 2.099 TPBG
trophoblast glycoprotein
chr3_-_53079959 2.093 SFMBT1
Scm-like with four mbt domains 1
chr8_+_16884745 2.080 NM_181723
EFHA2
EF-hand domain family, member A2
chr15_+_38544119 2.077 SPRED1
sprouty-related, EVH1 domain containing 1
chr11_+_120382420 2.068 GRIK4
glutamate receptor, ionotropic, kainate 4
chr13_-_38443859 2.066 NM_001135955
NM_001135956
NM_001135957
NM_001135958
NM_003306
NM_016179
TRPC4





transient receptor potential cation channel, subfamily C, member 4





chr2_-_96810775 2.060 DUSP2
dual specificity phosphatase 2
chr2_-_88752052 2.059 NM_001135649
FOXI3
forkhead box I3
chr16_+_84178864 2.057 NM_178452
DNAAF1
dynein, axonemal, assembly factor 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
1.90 7.24e-17 GO:0007275 multicellular organismal development
1.84 8.38e-17 GO:0032502 developmental process
1.84 6.01e-13 GO:0048856 anatomical structure development
2.34 2.55e-12 GO:0007399 nervous system development
1.86 9.29e-12 GO:0048731 system development
1.55 2.51e-11 GO:0032501 multicellular organismal process
2.04 4.44e-11 GO:0030154 cell differentiation
1.98 3.06e-10 GO:0048869 cellular developmental process
2.32 3.82e-10 GO:0051239 regulation of multicellular organismal process
1.37 5.66e-10 GO:0065007 biological regulation
2.57 1.03e-08 GO:0048699 generation of neurons
2.44 1.47e-08 GO:0006357 regulation of transcription from RNA polymerase II promoter
2.50 1.56e-08 GO:0022008 neurogenesis
1.38 3.83e-08 GO:0050794 regulation of cellular process
2.67 1.52e-07 GO:0030182 neuron differentiation
1.35 1.68e-07 GO:0050789 regulation of biological process
1.63 1.95e-07 GO:0060255 regulation of macromolecule metabolic process
1.58 6.34e-07 GO:0031323 regulation of cellular metabolic process
1.58 7.88e-07 GO:0080090 regulation of primary metabolic process
2.52 8.45e-07 GO:2000026 regulation of multicellular organismal development
2.35 9.34e-07 GO:0050793 regulation of developmental process
1.77 1.00e-06 GO:0051252 regulation of RNA metabolic process
1.69 3.00e-06 GO:0010468 regulation of gene expression
1.72 3.04e-06 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.76 3.91e-06 GO:0006355 regulation of transcription, DNA-dependent
1.65 6.84e-06 GO:0048518 positive regulation of biological process
2.59 7.58e-06 GO:0045893 positive regulation of transcription, DNA-dependent
2.40 9.01e-06 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.94 9.18e-06 GO:0009653 anatomical structure morphogenesis
2.37 9.34e-06 GO:0051173 positive regulation of nitrogen compound metabolic process
1.70 1.10e-05 GO:0048519 negative regulation of biological process
1.67 1.44e-05 GO:0010556 regulation of macromolecule biosynthetic process
1.79 1.95e-05 GO:0048513 organ development
1.64 2.17e-05 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.64 2.17e-05 GO:0031326 regulation of cellular biosynthetic process
2.21 2.23e-05 GO:0048468 cell development
1.49 2.56e-05 GO:0019222 regulation of metabolic process
2.35 3.64e-05 GO:0010557 positive regulation of macromolecule biosynthetic process
1.66 3.74e-05 GO:0048522 positive regulation of cellular process
2.26 3.84e-05 GO:0031328 positive regulation of cellular biosynthetic process
1.62 4.20e-05 GO:0009889 regulation of biosynthetic process
2.41 6.57e-05 GO:0051254 positive regulation of RNA metabolic process
2.61 6.58e-05 GO:0045892 negative regulation of transcription, DNA-dependent
1.60 6.80e-05 GO:0051171 regulation of nitrogen compound metabolic process
2.22 6.80e-05 GO:0009891 positive regulation of biosynthetic process
2.36 8.30e-05 GO:0009890 negative regulation of biosynthetic process
2.39 8.84e-05 GO:0010628 positive regulation of gene expression
2.55 1.15e-04 GO:0051253 negative regulation of RNA metabolic process
1.69 1.17e-04 GO:0048523 negative regulation of cellular process
2.36 1.18e-04 GO:0031327 negative regulation of cellular biosynthetic process
2.16 1.65e-04 GO:0006351 transcription, DNA-dependent
2.41 1.90e-04 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
2.43 2.00e-04 GO:0010629 negative regulation of gene expression
4.23 2.16e-04 GO:0045165 cell fate commitment
3.10 2.26e-04 GO:0022603 regulation of anatomical structure morphogenesis
2.36 2.51e-04 GO:0010558 negative regulation of macromolecule biosynthetic process
2.54 2.71e-04 GO:0008284 positive regulation of cell proliferation
2.32 2.83e-04 GO:0045595 regulation of cell differentiation
3.66 3.04e-04 GO:0045664 regulation of neuron differentiation
2.78 3.78e-04 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
2.39 4.67e-04 GO:0009887 organ morphogenesis
2.27 4.91e-04 GO:0009790 embryo development
2.63 5.92e-04 GO:0051094 positive regulation of developmental process
1.92 6.00e-04 GO:0031325 positive regulation of cellular metabolic process
2.57 6.92e-04 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
1.44 1.20e-03 GO:0023052 signaling
2.47 1.21e-03 GO:0007417 central nervous system development
2.90 1.45e-03 GO:0060284 regulation of cell development
2.29 2.06e-03 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
3.16 2.22e-03 GO:0050767 regulation of neurogenesis
2.26 2.82e-03 GO:0051172 negative regulation of nitrogen compound metabolic process
2.31 2.86e-03 GO:0048666 neuron development
1.60 2.88e-03 GO:0065008 regulation of biological quality
1.95 4.17e-03 GO:0032774 RNA biosynthetic process
1.81 4.34e-03 GO:0009893 positive regulation of metabolic process
2.40 4.67e-03 GO:0031175 neuron projection development
2.93 5.06e-03 GO:0051960 regulation of nervous system development
2.37 5.96e-03 GO:0000904 cell morphogenesis involved in differentiation
1.92 6.03e-03 GO:0009892 negative regulation of metabolic process
2.88 6.61e-03 GO:0007423 sensory organ development
1.82 9.22e-03 GO:0010604 positive regulation of macromolecule metabolic process
2.68 1.03e-02 GO:0007411 axon guidance
1.95 1.04e-02 GO:0031324 negative regulation of cellular metabolic process
1.67 1.12e-02 GO:0023051 regulation of signaling
3.88 1.33e-02 GO:0010769 regulation of cell morphogenesis involved in differentiation
1.90 1.36e-02 GO:0042127 regulation of cell proliferation
6.46 1.43e-02 GO:0001704 formation of primary germ layer
3.85 1.47e-02 GO:0022604 regulation of cell morphogenesis
2.38 2.17e-02 GO:0048667 cell morphogenesis involved in neuron differentiation
1.14 2.41e-02 GO:0009987 cellular process
2.38 2.93e-02 GO:0007409 axonogenesis
1.89 2.96e-02 GO:0010605 negative regulation of macromolecule metabolic process
2.33 3.04e-02 GO:0048812 neuron projection morphogenesis
1.98 3.13e-02 GO:0007267 cell-cell signaling
4.06 3.25e-02 GO:0010720 positive regulation of cell development
3.11 3.93e-02 GO:0032582 negative regulation of gene-specific transcription
2.11 4.09e-02 GO:0000902 cell morphogenesis
3.37 4.11e-02 GO:0010553 negative regulation of gene-specific transcription from RNA polymerase II promoter
1.50 4.46e-02 GO:0042221 response to chemical stimulus
3.68 4.85e-02 GO:0010975 regulation of neuron projection development
1.79 4.91e-02 GO:0010646 regulation of cell communication

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
1.36 1.33e-05 GO:0005634 nucleus
3.98 3.29e-04 GO:0034703 cation channel complex
2.23 5.33e-04 GO:0030054 cell junction
3.19 7.65e-04 GO:0034702 ion channel complex
2.36 4.72e-03 GO:0045202 synapse
1.50 6.46e-03 GO:0044459 plasma membrane part
7.62 6.55e-03 GO:0034704 calcium channel complex
2.73 8.35e-03 GO:0005667 transcription factor complex
9.02 8.87e-03 GO:0005891 voltage-gated calcium channel complex
1.62 2.63e-02 GO:0005654 nucleoplasm
2.41 3.44e-02 GO:0044456 synapse part
1.30 4.19e-02 GO:0005886 plasma membrane

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
2.39 1.94e-09 GO:0030528 transcription regulator activity
2.24 2.34e-07 GO:0001071 nucleic acid binding transcription factor activity
2.24 2.34e-07 GO:0003700 sequence-specific DNA binding transcription factor activity
3.05 4.04e-05 GO:0016564 transcription repressor activity
5.26 1.38e-04 GO:0003705 sequence-specific enhancer binding RNA polymerase II transcription factor activity
2.21 2.29e-04 GO:0043565 sequence-specific DNA binding
2.87 2.36e-04 GO:0016563 transcription activator activity
4.75 4.98e-04 GO:0000981 sequence-specific DNA binding RNA polymerase II transcription factor activity
4.56 1.90e-03 GO:0003704 specific RNA polymerase II transcription factor activity
1.52 2.33e-03 GO:0003677 DNA binding
5.74 2.90e-03 GO:0008301 DNA bending activity
3.56 4.35e-03 GO:0022843 voltage-gated cation channel activity
4.23 4.41e-03 GO:0016566 specific transcriptional repressor activity
2.65 5.79e-03 GO:0008134 transcription factor binding
1.40 6.13e-03 GO:0003676 nucleic acid binding
2.70 1.52e-02 GO:0003702 RNA polymerase II transcription factor activity
2.41 3.69e-02 GO:0022836 gated channel activity
7.29 4.99e-02 GO:0005245 voltage-gated calcium channel activity