Motif ID: CTCF.p2

Z-value: 2.021


Transcription factors associated with CTCF.p2:

Gene SymbolEntrez IDGene Name
CTCF 10664 CCCTC-binding factor (zinc finger protein)

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
CTCFhg19_v1_chr16_+_67596309_67596479-0.431.1e-04Click!


Activity profile for motif CTCF.p2.

activity profile for motif CTCF.p2


Sorted Z-values histogram for motif CTCF.p2

Sorted Z-values for motif CTCF.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of CTCF.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_+_159626047 17.137 NM_001040442
FABP6
fatty acid binding protein 6, ileal
chr16_-_2390737 13.117 NM_001089
ABCA3
ATP-binding cassette, sub-family A (ABC1), member 3
chr1_+_145524989 12.697 NM_003637
ITGA10
integrin, alpha 10
chr10_+_99332197 12.404 NM_001129981
NM_020349
ANKRD2

ankyrin repeat domain 2 (stretch responsive muscle)

chr4_-_141348760 11.823 NM_001130675
NM_004362
CLGN

calmegin

chr7_+_100081549 11.622 NM_173564
NYAP1
neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 1
chr16_-_2390593 11.461 ABCA3
ATP-binding cassette, sub-family A (ABC1), member 3
chr9_+_116917716 10.919 COL27A1
collagen, type XXVII, alpha 1
chr11_+_61447816 10.682 NM_006133
DAGLA
diacylglycerol lipase, alpha
chr16_-_2390711 10.615 ABCA3
ATP-binding cassette, sub-family A (ABC1), member 3
chr14_-_107211131 9.786 IGHG1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr12_-_7245006 9.677 NM_001733
C1R
complement component 1, r subcomponent
chr19_+_49977465 9.630 NM_001204502
NM_001459
FLT3LG

fms-related tyrosine kinase 3 ligand

chr6_+_138188352 8.188 NM_006290
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr17_-_18528844 8.170 CCDC144B
coiled-coil domain containing 144B (pseudogene)
chr9_+_131183122 8.146 CERCAM
cerebral endothelial cell adhesion molecule
chr1_+_145525041 8.069 ITGA10
integrin, alpha 10
chr12_+_104609501 7.748 NM_001093771
TXNRD1
thioredoxin reductase 1
chr18_+_14179298 7.587 ANKRD20A5P
ankyrin repeat domain 20 family, member A5, pseudogene
chr17_+_16593571 7.518 NM_014695
CCDC144B
CCDC144A
coiled-coil domain containing 144B (pseudogene)
coiled-coil domain containing 144A
chr12_-_7245048 7.497 C1R
complement component 1, r subcomponent
chr19_-_6481765 7.415 NM_024898
DENND1C
DENN/MADD domain containing 1C
chr10_+_104154228 7.359 NM_001077493
NM_001077494
NFKB2

nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)

chr9_+_131182690 7.235 NM_016174
CERCAM
cerebral endothelial cell adhesion molecule
chr19_-_49496369 6.779 GYS1
glycogen synthase 1 (muscle)
chr16_+_23194037 6.724 NM_001039
SCNN1G
sodium channel, nonvoltage-gated 1, gamma
chr10_+_5136589 6.577 AKR1C3
aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
chr9_+_139738866 6.529 NM_001080482
C9orf172
chromosome 9 open reading frame 172
chr19_+_12949258 6.480 NM_014975
MAST1
microtubule associated serine/threonine kinase 1
chr19_-_49496564 6.448 GYS1
glycogen synthase 1 (muscle)
chr19_-_49496520 6.395 GYS1
glycogen synthase 1 (muscle)
chr3_-_49757058 6.135 NM_198722
AMIGO3
adhesion molecule with Ig-like domain 3
chr19_-_49496566 6.069 NM_001161587
NM_002103
GYS1

glycogen synthase 1 (muscle)

chr19_+_48216600 5.888 NM_014601
EHD2
EH-domain containing 2
chr20_+_36531498 5.807 NM_080607
VSTM2L
V-set and transmembrane domain containing 2 like
chr16_-_90085786 5.758 NM_001042610
DBNDD1
dysbindin (dystrobrevin binding protein 1) domain containing 1
chr10_+_5136556 5.629 NM_003739
AKR1C3
aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
chr5_+_148520985 5.597 NM_014945
ABLIM3
actin binding LIM protein family, member 3
chr9_+_131901687 5.539


chr12_-_7261788 5.517 NM_016546
C1RL
complement component 1, r subcomponent-like
chr17_+_43213013 5.495 NM_001135705
NM_001135706
NM_001135707
NM_024722
ACBD4



acyl-CoA binding domain containing 4



chr20_+_36531548 5.477 VSTM2L
V-set and transmembrane domain containing 2 like
chr19_+_49977817 5.472 NM_001204503
FLT3LG
fms-related tyrosine kinase 3 ligand
chrX_-_153141398 5.335 NM_000425
NM_001143963
NM_024003
L1CAM


L1 cell adhesion molecule


chr9_-_133814422 5.226 NM_001145106
FIBCD1
fibrinogen C domain containing 1
chr19_-_59030920 5.196 NM_032792
ZBTB45
zinc finger and BTB domain containing 45
chr19_+_38893766 5.159 NM_174905
FAM98C
family with sequence similarity 98, member C
chrX_-_153141284 5.093 L1CAM
L1 cell adhesion molecule
chr19_+_54041332 5.007 NM_001079906
NM_001253798
NM_001253799
ZNF331


zinc finger protein 331


chr10_-_76995685 4.977 NM_144589
COMTD1
catechol-O-methyltransferase domain containing 1
chr1_-_94375028 4.934 GCLM
glutamate-cysteine ligase, modifier subunit
chr2_+_234263153 4.893 DGKD
diacylglycerol kinase, delta 130kDa
chr1_+_9294857 4.847 NM_004285
H6PD
hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
chr2_+_228678556 4.797 NM_001130046
NM_004591
CCL20

chemokine (C-C motif) ligand 20

chr19_+_56165415 4.797 NM_001012478
NM_007279
U2AF2

U2 small nuclear RNA auxiliary factor 2

chr9_-_112083196 4.785 EPB41L4B
erythrocyte membrane protein band 4.1 like 4B
chr9_+_140317803 4.754 NM_006647
NOXA1
NADPH oxidase activator 1
chr15_-_40630272 4.672 C15orf52
chromosome 15 open reading frame 52
chr19_+_38893804 4.656 FAM98C
family with sequence similarity 98, member C
chr2_-_24307179 4.638 NM_001206802
TP53I3
tumor protein p53 inducible protein 3
chr1_-_94374949 4.620 GCLM
glutamate-cysteine ligase, modifier subunit
chr19_+_50094911 4.588 NM_020719
PRR12
proline rich 12
chr1_-_94374986 4.579 NM_002061
GCLM
glutamate-cysteine ligase, modifier subunit
chr3_-_196756682 4.560 NM_033316
NM_005929
MFI2

antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5

chr14_+_105190533 4.472 NM_152328
ADSSL1
adenylosuccinate synthase like 1
chr8_+_17434700 4.464 PDGFRL
platelet-derived growth factor receptor-like
chr19_-_36001336 4.445 NM_001126059
DMKN
dermokine
chr19_+_40477032 4.418 NM_006503
NM_153001
PSMC4

proteasome (prosome, macropain) 26S subunit, ATPase, 4

chr13_-_101241007 4.410 NM_001195087
A2LD1
AIG2-like domain 1
chr16_-_90086264 4.398 DBNDD1
dysbindin (dystrobrevin binding protein 1) domain containing 1
chr20_-_42939737 4.386 NM_001080472
FITM2
fat storage-inducing transmembrane protein 2
chr7_-_100171269 4.353 NM_001168682
SAP25
Sin3A-associated protein, 25kDa
chr16_+_2867227 4.314 PRSS21
protease, serine, 21 (testisin)
chr2_+_69240137 4.224 NM_018153
NM_032208
NM_053034
ANTXR1


anthrax toxin receptor 1


chr19_+_38893828 4.176 FAM98C
family with sequence similarity 98, member C
chr2_+_234263141 4.173 NM_152879
DGKD
diacylglycerol kinase, delta 130kDa
chr9_+_34646608 4.167 NM_000155
GALT
galactose-1-phosphate uridylyltransferase
chr15_-_75194542 4.162 C15orf17
chromosome 15 open reading frame 17
chr19_+_39903749 4.102 NM_022835
PLEKHG2
pleckstrin homology domain containing, family G (with RhoGef domain) member 2
chr9_-_112083005 4.091 NM_018424
NM_019114
EPB41L4B

erythrocyte membrane protein band 4.1 like 4B

chr12_+_49208615 3.997 CACNB3
calcium channel, voltage-dependent, beta 3 subunit
chr9_+_34646600 3.967 GALT
galactose-1-phosphate uridylyltransferase
chr19_+_42829760 3.960 NM_001410
MEGF8
multiple EGF-like-domains 8
chr1_+_37940180 3.954 ZC3H12A
zinc finger CCCH-type containing 12A
chr16_+_67313390 3.945 NM_001129729
NM_001129731
PLEKHG4

pleckstrin homology domain containing, family G (with RhoGef domain) member 4

chr20_-_30311693 3.941 BCL2L1
BCL2-like 1
chr1_+_211433285 3.908 NM_018254
RCOR3
REST corepressor 3
chr19_+_47852537 3.884 NM_014681
DHX34
DEAH (Asp-Glu-Ala-His) box polypeptide 34
chr7_+_148959219 3.881 NM_001195220
ZNF783
zinc finger family member 783
chr9_-_101558494 3.879 NM_173551
ANKS6
ankyrin repeat and sterile alpha motif domain containing 6
chr1_+_9294797 3.829 H6PD
hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
chr9_-_140317583 3.829 EXD3
exonuclease 3'-5' domain containing 3
chr15_+_101390032 3.804 LOC145757
uncharacterized LOC145757
chr8_+_21924369 3.762 EPB49
erythrocyte membrane protein band 4.9 (dematin)
chr16_-_2301560 3.719 NM_001178029
NM_001919
ECI1

enoyl-CoA delta isomerase 1

chr19_-_3028901 3.692 NM_003260
TLE2
transducin-like enhancer of split 2 (E(sp1) homolog, Drosophila)
chr17_-_73901142 3.680 NM_032478
MRPL38
mitochondrial ribosomal protein L38
chr5_-_92916924 3.663 FLJ42709
uncharacterized LOC441094
chr1_+_37940129 3.652 ZC3H12A
zinc finger CCCH-type containing 12A
chr7_-_27183225 3.611 NM_019102
HOXA5
homeobox A5
chr7_+_90338711 3.605 NM_012395
CDK14
cyclin-dependent kinase 14
chr9_+_140122017 3.580 NM_001190228
RNF224
ring finger protein 224
chr3_+_50297644 3.535


chr3_-_196756572 3.516 MFI2
antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5
chr16_-_790888 3.500 NM_022493
NARFL
nuclear prelamin A recognition factor-like
chr16_-_90086299 3.487 DBNDD1
dysbindin (dystrobrevin binding protein 1) domain containing 1
chr20_+_48807460 3.481 CEBPB
CCAAT/enhancer binding protein (C/EBP), beta
chr19_-_48018317 3.478 NM_003827
NAPA
N-ethylmaleimide-sensitive factor attachment protein, alpha
chr22_-_50964856 3.455 NM_001169109
SCO2
SCO cytochrome oxidase deficient homolog 2 (yeast)
chr7_+_112120907 3.448 NM_001134468
NM_182597
C7orf53

chromosome 7 open reading frame 53

chr12_-_109531244 3.409 NM_001001655
NM_001145374
NM_001145375
NM_001205179
NM_001205180
ALKBH2




alkB, alkylation repair homolog 2 (E. coli)




chr13_+_31774122 3.404 B3GALTL
beta 1,3-galactosyltransferase-like
chr10_+_81107228 3.345 PPIF
peptidylprolyl isomerase F
chr19_+_38826442 3.336 NM_021185
CATSPERG
cation channel, sperm-associated, gamma
chr22_-_50964573 3.333 NM_001169110
SCO2
SCO cytochrome oxidase deficient homolog 2 (yeast)
chr7_-_122526781 3.316 NM_001009571
NM_001167940
NM_017954
CADPS2


Ca++-dependent secretion activator 2


chr17_-_73900934 3.306 MRPL38
mitochondrial ribosomal protein L38
chr7_-_122526410 3.275 CADPS2
Ca++-dependent secretion activator 2
chr19_-_46088021 3.256 OPA3
optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
chr21_+_45725058 3.247 PFKL
phosphofructokinase, liver
chr19_-_2051222 3.214 NM_017572
NM_199054
MKNK2

MAP kinase interacting serine/threonine kinase 2

chrX_+_153029578 3.201 NM_001163257
NM_005393
PLXNB3

plexin B3

chr6_-_41747586 3.198 NM_006653
FRS3
fibroblast growth factor receptor substrate 3
chr17_-_48474864 3.196 LRRC59
leucine rich repeat containing 59
chr10_+_35416089 3.190 CREM
cAMP responsive element modulator
chr11_-_798196 3.184 NM_001191061
SLC25A22
solute carrier family 25 (mitochondrial carrier: glutamate), member 22
chr10_+_81107219 3.130 NM_005729
PPIF
peptidylprolyl isomerase F
chr10_+_81107259 3.128 PPIF
peptidylprolyl isomerase F
chr9_-_140142165 3.098 NM_001001710
FAM166A
family with sequence similarity 166, member A
chr5_+_176513819 3.085 NM_002011
NM_213647
FGFR4

fibroblast growth factor receptor 4

chr15_-_101459410 3.080


chr20_+_48807119 3.075 NM_005194
CEBPB
CCAAT/enhancer binding protein (C/EBP), beta
chr10_-_15413054 3.041 NM_001010924
FAM171A1
family with sequence similarity 171, member A1
chr6_-_33547833 3.034 BAK1
BCL2-antagonist/killer 1
chr12_+_58176527 3.029 NM_001172695
NM_001172696
NM_001172697
NM_005726
TSFM



Ts translation elongation factor, mitochondrial



chr8_-_101571870 3.024 NM_198401
GAPDHP62
ANKRD46
glyceraldehyde 3 phosphate dehydrogenase pseudogene 62
ankyrin repeat domain 46
chr13_-_53024730 3.020 NM_016075
VPS36
vacuolar protein sorting 36 homolog (S. cerevisiae)
chr1_+_151129104 3.016 NM_001204848
NM_024575
TNFAIP8L2-SCNM1
TNFAIP8L2
TNFAIP8L2-SCNM1 readthrough
tumor necrosis factor, alpha-induced protein 8-like 2
chr18_-_57364572 3.015 CCBE1
collagen and calcium binding EGF domains 1
chr13_+_31774087 3.013 NM_194318
B3GALTL
beta 1,3-galactosyltransferase-like
chr19_-_59031167 2.989 ZBTB45
zinc finger and BTB domain containing 45
chr22_-_22307188 2.975 PPM1F
protein phosphatase, Mg2+/Mn2+ dependent, 1F
chr8_+_143808593 2.959 NM_016647
C8orf55
chromosome 8 open reading frame 55
chr10_+_81107242 2.930 PPIF
peptidylprolyl isomerase F
chr20_+_32319765 2.926 NM_032819
ZNF341
zinc finger protein 341
chr22_-_50765405 2.915 NM_001001794
FAM116B
family with sequence similarity 116, member B
chr22_-_22307212 2.891 NM_014634
PPM1F
protein phosphatase, Mg2+/Mn2+ dependent, 1F
chrX_-_117119282 2.879 NM_001168299
KLHL13
kelch-like 13 (Drosophila)
chr17_-_78009453 2.875 NM_019020
TBC1D16
TBC1 domain family, member 16
chr7_+_101459092 2.874 NM_001202543
NM_001202544
NM_001202545
NM_001913
NM_181500
NM_001202546
CUX1





cut-like homeobox 1





chr4_-_140216951 2.871 NDUFC1
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa
chr19_-_58400287 2.870 NM_001144989
ZNF814
zinc finger protein 814
chr2_-_209119751 2.869 NM_005896
IDH1
isocitrate dehydrogenase 1 (NADP+), soluble
chr7_+_148844440 2.859 NM_170686
ZNF398
zinc finger protein 398
chr17_-_5342380 2.855 C1QBP
complement component 1, q subcomponent binding protein
chr15_-_79103571 2.851 NM_014272
ADAMTS7
ADAM metallopeptidase with thrombospondin type 1 motif, 7
chr19_+_17416476 2.845 NM_023937
MRPL34
mitochondrial ribosomal protein L34
chr1_+_223900212 2.837 CAPN2
calpain 2, (m/II) large subunit
chr14_-_107218786 2.828 IGHA1
IGHG1
IGHM
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant mu
chr7_+_75831194 2.827 NM_001110199
SRRM3
serine/arginine repetitive matrix 3
chr8_-_145911160 2.804 ARHGAP39
Rho GTPase activating protein 39
chr9_+_131798899 2.804 FAM73B
family with sequence similarity 73, member B
chr1_+_37940074 2.802 NM_025079
ZC3H12A
zinc finger CCCH-type containing 12A
chr1_-_114447635 2.799 NM_006594
AP4B1
adaptor-related protein complex 4, beta 1 subunit
chr16_-_23607603 2.792 NM_005003
NDUFAB1
NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1, 8kDa
chr1_+_11539177 2.760 NM_020780
PTCHD2
patched domain containing 2
chr12_+_13197284 2.740 NM_020853
KIAA1467
KIAA1467
chr1_+_223900328 2.728 CAPN2
calpain 2, (m/II) large subunit
chr2_+_223289285 2.723 NM_152386
SGPP2
sphingosine-1-phosphate phosphatase 2
chr17_+_48556180 2.721 NM_018346
RSAD1
radical S-adenosyl methionine domain containing 1
chr8_-_146012653 2.718 NM_030580
ZNF34
zinc finger protein 34
chr10_-_6019880 2.709 NM_001243539
IL15RA
interleukin 15 receptor, alpha
chr17_-_61523544 2.707 NM_001017916
NM_001915
CYB561

cytochrome b-561

chr12_+_49208214 2.702 NM_001206917
CACNB3
calcium channel, voltage-dependent, beta 3 subunit
chr19_-_54663434 2.663 NM_024316
LENG1
leukocyte receptor cluster (LRC) member 1
chr11_+_64018991 2.656 NM_000932
NM_001184883
PLCB3

phospholipase C, beta 3 (phosphatidylinositol-specific)

chr14_+_23305907 2.655 MMP14
matrix metallopeptidase 14 (membrane-inserted)
chr16_-_70713927 2.649 MTSS1L
metastasis suppressor 1-like
chr11_+_64018996 2.633 PLCB3
phospholipase C, beta 3 (phosphatidylinositol-specific)
chr1_-_114447338 2.628 AP4B1
adaptor-related protein complex 4, beta 1 subunit
chr17_-_79995555 2.608 NM_001195218
NM_016286
DCXR

dicarbonyl/L-xylulose reductase

chr19_+_18699494 2.606 NM_001100418
NM_001100419
C19orf60

chromosome 19 open reading frame 60

chr17_-_33469269 2.593 NM_001014445
NM_018096
NLE1

notchless homolog 1 (Drosophila)

chr12_+_7033625 2.576 NM_001007026
ATN1
atrophin 1
chr5_-_118324223 2.567 NM_173666
DTWD2
DTW domain containing 2
chr16_+_30406711 2.562 NM_152652
ZNF48
zinc finger protein 48
chr17_-_48474870 2.562 LRRC59
leucine rich repeat containing 59
chr6_-_41006927 2.560 NM_173561
UNC5CL
unc-5 homolog C (C. elegans)-like
chr19_-_46088074 2.560 OPA3
optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
chr8_+_54764367 2.557 NM_170587
RGS20
regulator of G-protein signaling 20
chrX_-_131353460 2.554 RAP2C
RAP2C, member of RAS oncogene family
chr17_+_73996986 2.550 NM_001258
CDK3
cyclin-dependent kinase 3
chrX_-_19533378 2.541 NM_001001671
MAP3K15
mitogen-activated protein kinase kinase kinase 15
chr3_-_49967194 2.539 NM_001142501
NM_032355
MON1A

MON1 homolog A (yeast)

chr17_+_48556217 2.526 RSAD1
radical S-adenosyl methionine domain containing 1
chr2_-_74709965 2.522 CCDC142
coiled-coil domain containing 142
chr14_+_23305816 2.518 MMP14
matrix metallopeptidase 14 (membrane-inserted)
chr3_-_47517316 2.517 SCAP
SREBF chaperone
chr12_+_110338064 2.510 NM_001143852
TCHP
trichoplein, keratin filament binding
chr3_-_47517417 2.498 NM_012235
SCAP
SREBF chaperone

Gene Ontology Analysis

Nothing significant found in process category.

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
1.41 4.71e-05 GO:0044444 cytoplasmic part
1.68 5.32e-03 GO:0005829 cytosol
1.25 5.33e-03 GO:0005737 cytoplasm
1.79 2.94e-02 GO:0005739 mitochondrion
3.03 3.31e-02 GO:0005759 mitochondrial matrix

Nothing significant found in function category.