Motif ID: CREB1.p2

Z-value: 1.430


Transcription factors associated with CREB1.p2:

Gene SymbolEntrez IDGene Name
CREB1 1385 cAMP responsive element binding protein 1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
CREB1hg19_v1_chr2_+_208394823_208394828-0.253.0e-02Click!


Activity profile for motif CREB1.p2.

activity profile for motif CREB1.p2


Sorted Z-values histogram for motif CREB1.p2

Sorted Z-values for motif CREB1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of CREB1.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr19_+_54058493 11.534 NM_001079907
ZNF331
zinc finger protein 331
chr19_-_5340700 11.104 NM_002850
NM_130853
NM_130854
NM_130855
PTPRS



protein tyrosine phosphatase, receptor type, S



chr2_-_224467049 9.911 SCG2
secretogranin II
chr11_-_119252364 8.546 NM_001243759
NM_004205
USP2

ubiquitin specific peptidase 2

chr2_-_224467095 8.190 SCG2
secretogranin II
chr11_-_119252267 8.175 USP2
ubiquitin specific peptidase 2
chr19_-_46088084 6.967 NM_001017989
NM_025136
OPA3

optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)

chr19_+_45971249 6.241 NM_001114171
NM_006732
FOSB

FBJ murine osteosarcoma viral oncogene homolog B

chr19_-_46088074 6.090 OPA3
optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
chr19_-_46088021 5.962 OPA3
optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
chr19_+_49375679 5.874 PPP1R15A
protein phosphatase 1, regulatory subunit 15A
chr4_+_75230856 5.786 NM_001432
EREG
epiregulin
chr19_+_54960380 5.694 LENG8
leukocyte receptor cluster (LRC) member 8
chr19_+_49375677 5.537 PPP1R15A
protein phosphatase 1, regulatory subunit 15A
chr2_-_224467142 5.470 NM_003469
SCG2
secretogranin II
chr19_+_49375638 5.453 NM_014330
PPP1R15A
protein phosphatase 1, regulatory subunit 15A
chr2_+_28615695 5.351 FOSL2
FOS-like antigen 2
chr17_-_8151353 5.070 CTC1
CTS telomere maintenance complex component 1
chr5_-_172198160 4.900 NM_004417
DUSP1
dual specificity phosphatase 1
chr19_+_54694118 4.886 NM_024075
TSEN34
tRNA splicing endonuclease 34 homolog (S. cerevisiae)
chr1_+_212782103 4.777 ATF3
activating transcription factor 3
chr20_+_33292117 4.720 NM_021202
TP53INP2
tumor protein p53 inducible nuclear protein 2
chr10_+_123923104 4.610 NM_006997
NM_206860
TACC2

transforming, acidic coiled-coil containing protein 2

chr16_+_56225250 4.577 NM_020988
NM_138736
GNAO1

guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O

chr2_+_28615668 4.491 FOSL2
FOS-like antigen 2
chr17_-_8151373 4.460 NM_025099
CTC1
CTS telomere maintenance complex component 1
chr12_+_52445185 4.323 NM_002135
NM_173157
NR4A1

nuclear receptor subfamily 4, group A, member 1

chr16_+_56225301 4.241 GNAO1
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
chr2_+_28615771 4.240 NM_005253
FOSL2
FOS-like antigen 2
chr19_+_44100543 4.158 NM_024327
ZNF576
zinc finger protein 576
chr1_-_204121144 4.153 NM_018208
ETNK2
ethanolamine kinase 2
chr19_-_55574434 4.122 NM_001145971
RDH13
retinol dehydrogenase 13 (all-trans/9-cis)
chr19_-_18392413 4.046 NM_005354
JUND
jun D proto-oncogene
chr11_-_66610703 3.945


chr18_+_76829391 3.920 NM_198531
ATP9B
ATPase, class II, type 9B
chr2_+_85980600 3.840 NM_032827
ATOH8
atonal homolog 8 (Drosophila)
chr19_+_54057898 3.837 NM_001253801
ZNF331
zinc finger protein 331
chr7_-_158622202 3.832 NM_020728
ESYT2
extended synaptotagmin-like protein 2
chr1_-_15850692 3.764 CASP9
caspase 9, apoptosis-related cysteine peptidase
chr19_-_55628780 3.757 NM_017607
PPP1R12C
protein phosphatase 1, regulatory subunit 12C
chr19_+_54619114 3.728 PRPF31
PRP31 pre-mRNA processing factor 31 homolog (S. cerevisiae)
chr19_+_18043812 3.720 NM_001136203
CCDC124
coiled-coil domain containing 124
chr19_-_2702662 3.703 GNG7
guanine nucleotide binding protein (G protein), gamma 7
chr3_+_183165402 3.687 LOC100505687
uncharacterized LOC100505687
chr19_+_54619149 3.648 PRPF31
PRP31 pre-mRNA processing factor 31 homolog (S. cerevisiae)
chr1_-_15850776 3.619 NM_001229
NM_032996
CASP9

caspase 9, apoptosis-related cysteine peptidase

chr19_+_1753661 3.618 NM_001080488
ONECUT3
one cut homeobox 3
chr19_-_44100127 3.609 NM_001007561
IRGQ
immunity-related GTPase family, Q
chr11_-_2017822 3.604 H19
H19, imprinted maternally expressed transcript (non-protein coding)
chr16_+_726074 3.599 NM_003961
RHBDL1
rhomboid, veinlet-like 1 (Drosophila)
chr19_+_59055826 3.595 NM_005762
TRIM28
tripartite motif containing 28
chr16_-_88772732 3.566 NM_001171815
RNF166
ring finger protein 166
chr11_+_102188180 3.549 NM_001165
NM_182962
BIRC3

baculoviral IAP repeat containing 3

chr17_-_7166263 3.543 NM_001185023
NM_001307
CLDN7

claudin 7

chr12_+_54378929 3.505 NM_017409
HOXC10
homeobox C10
chrX_+_43514157 3.497 MAOA
monoamine oxidase A
chr22_+_38597938 3.458 NM_001161572
NM_001161574
NM_012323
MAFF


v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian)


chr16_+_725679 3.367 RHBDL1
rhomboid, veinlet-like 1 (Drosophila)
chr19_-_49496369 3.363 GYS1
glycogen synthase 1 (muscle)
chr19_+_54042041 3.335 NM_001253800
ZNF331
zinc finger protein 331
chr13_+_49822046 3.328 NM_001193478
NM_030911
CDADC1

cytidine and dCMP deaminase domain containing 1

chr15_+_62682682 3.326 TLN2
talin 2
chr19_-_47987410 3.278 KPTN
kaptin (actin binding protein)
chr1_-_155881063 3.275 RIT1
Ras-like without CAAX 1
chr14_-_77494974 3.260 NM_024496
IRF2BPL
interferon regulatory factor 2 binding protein-like
chr9_-_140082983 3.233 ANAPC2
anaphase promoting complex subunit 2
chr19_-_49496520 3.229 GYS1
glycogen synthase 1 (muscle)
chr7_+_1200097 3.217


chr19_-_49496564 3.191 GYS1
glycogen synthase 1 (muscle)
chr4_+_75174189 3.146 NM_001013442
EPGN
epithelial mitogen homolog (mouse)
chr14_+_105190533 3.146 NM_152328
ADSSL1
adenylosuccinate synthase like 1
chr19_+_39833096 3.137 SAMD4B
sterile alpha motif domain containing 4B
chr11_-_61735067 3.117 FTH1
CPSF7
ferritin, heavy polypeptide 1
cleavage and polyadenylation specific factor 7, 59kDa
chr22_+_38598065 3.113 MAFF
v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian)
chr4_-_8442427 3.111 NM_001101667
NM_003501
ACOX3

acyl-CoA oxidase 3, pristanoyl

chr2_-_157189040 3.107 NM_006186
NR4A2
nuclear receptor subfamily 4, group A, member 2
chr16_+_71879858 3.102


chr9_-_140083010 3.102 ANAPC2
anaphase promoting complex subunit 2
chr11_-_61735108 3.092 NM_002032
FTH1
ferritin, heavy polypeptide 1
chr6_+_126277847 3.080 NM_138571
HINT3
histidine triad nucleotide binding protein 3
chr19_+_39833132 3.072 SAMD4B
sterile alpha motif domain containing 4B
chr1_-_204120909 3.060 ETNK2
ethanolamine kinase 2
chr16_+_15528324 3.048 NM_033201
C16orf45
chromosome 16 open reading frame 45
chr14_-_102975996 3.044 ANKRD9
ankyrin repeat domain 9
chr6_-_166401526 3.023 LINC00473
long intergenic non-protein coding RNA 473
chr3_+_47021146 3.017 NM_015175
NBEAL2
neurobeachin-like 2
chr18_+_7567313 3.010 NM_001105244
NM_002845
PTPRM

protein tyrosine phosphatase, receptor type, M

chr12_-_53448167 3.002 LOC283335
uncharacterized LOC283335
chr19_+_50354417 2.991 PTOV1
prostate tumor overexpressed 1
chr19_-_39402797 2.967 NM_001243212
LOC643669
uncharacterized LOC643669
chr19_-_18392436 2.942 JUND
jun D proto-oncogene
chr19_-_47987475 2.926 NM_007059
KPTN
kaptin (actin binding protein)
chr15_-_40401041 2.918 NM_001003940
BMF
Bcl2 modifying factor
chr6_-_31939658 2.914 DOM3Z
dom-3 homolog Z (C. elegans)
chr19_-_29704021 2.905 UQCRFS1
ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1
chr19_+_54618789 2.903 NM_015629
PRPF31
PRP31 pre-mRNA processing factor 31 homolog (S. cerevisiae)
chr19_+_38042275 2.898 NM_152606
LOC100507433
ZNF540
uncharacterized LOC100507433
zinc finger protein 540
chr1_-_155881163 2.897 NM_006912
RIT1
Ras-like without CAAX 1
chr14_-_77494621 2.894 IRF2BPL
interferon regulatory factor 2 binding protein-like
chr2_-_240964807 2.881 NM_004544
NDUFA10
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa
chr17_-_7165788 2.857 CLDN7
claudin 7
chr3_-_10067989 2.837 CIDECP
cell death-inducing DFFA-like effector c pseudogene
chr1_+_119683006 2.828


chr1_-_119683210 2.818 NM_015836
NM_201263
WARS2

tryptophanyl tRNA synthetase 2, mitochondrial

chr19_-_29704107 2.805 NM_006003
UQCRFS1
ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1
chr19_-_54619025 2.803 NM_013342
TFPT
TCF3 (E2A) fusion partner (in childhood Leukemia)
chr7_-_158622184 2.793 ESYT2
extended synaptotagmin-like protein 2
chr8_-_101322180 2.777 RNF19A
ring finger protein 19A
chr19_+_50353942 2.776 PTOV1
prostate tumor overexpressed 1
chr19_+_39833099 2.772 NM_018028
SAMD4B
sterile alpha motif domain containing 4B
chr15_+_52472257 2.765 LOC100129973
uncharacterized LOC100129973
chr17_+_80186886 2.749 NM_004207
SLC16A3
solute carrier family 16, member 3 (monocarboxylic acid transporter 4)
chr19_+_13263890 2.749 IER2
immediate early response 2
chr1_+_55446464 2.749 NM_182532
TMEM61
transmembrane protein 61
chr19_-_49496566 2.738 NM_001161587
NM_002103
GYS1

glycogen synthase 1 (muscle)

chr6_-_28303910 2.703 NM_001135216
NM_001243243
ZNF323

zinc finger protein 323

chr6_+_35227478 2.690 NM_003427
ZNF76
zinc finger protein 76
chr17_-_71308118 2.678 NM_012121
CDC42EP4
CDC42 effector protein (Rho GTPase binding) 4
chr7_+_44646120 2.664 NM_001003941
NM_001165036
NM_002541
OGDH


oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)


chr10_+_114709963 2.661 NM_001146274
NM_001146283
NM_001146284
NM_001146285
NM_001146286
NM_001198525
NM_001198526
NM_001198527
NM_001198528
NM_001198529
NM_001198530
NM_001198531
NM_030756
TCF7L2












transcription factor 7-like 2 (T-cell specific, HMG-box)












chr14_+_61447831 2.649 NM_001172702
NM_153811
SLC38A6

solute carrier family 38, member 6

chr11_-_61734896 2.643 FTH1
ferritin, heavy polypeptide 1
chr19_-_6481765 2.641 NM_024898
DENND1C
DENN/MADD domain containing 1C
chr7_+_44646168 2.621 OGDH
oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
chr8_+_59465798 2.613 SDCBP
syndecan binding protein (syntenin)
chr15_-_55700456 2.602 NM_004748
NM_001204450
NM_001204451
NM_020739
CCPG1



cell cycle progression 1



chr2_-_192015733 2.583 STAT4
signal transducer and activator of transcription 4
chr7_+_44646189 2.583 OGDH
oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
chr9_-_84304378 2.580 TLE1
transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
chr2_-_192015706 2.569 STAT4
signal transducer and activator of transcription 4
chr19_-_43969723 2.567 NM_014400
LYPD3
LY6/PLAUR domain containing 3
chr2_-_240964717 2.566 NDUFA10
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa
chr3_+_141087298 2.522 ZBTB38
zinc finger and BTB domain containing 38
chr2_+_42721697 2.521 MTA3
metastasis associated 1 family, member 3
chr7_+_44646197 2.511 OGDH
oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
chr19_+_48248792 2.506 NM_015710
GLTSCR2
glioma tumor suppressor candidate region gene 2
chr6_+_35227234 2.488 ZNF76
zinc finger protein 76
chr3_+_185000714 2.487 NM_001242314
NM_001242317
MAP3K13

mitogen-activated protein kinase kinase kinase 13

chr19_+_48248798 2.480 GLTSCR2
glioma tumor suppressor candidate region gene 2
chr8_+_59465783 2.477 SDCBP
syndecan binding protein (syntenin)
chr17_-_13505217 2.465 NM_006042
HS3ST3A1
heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1
chr3_+_9975513 2.459 NM_015513
NM_001031717
NM_001077415
CRELD1


cysteine-rich with EGF-like domains 1


chr9_+_37650996 2.451 NM_014907
FRMPD1
FERM and PDZ domain containing 1
chr19_+_50354368 2.437 NM_017432
PTOV1
prostate tumor overexpressed 1
chr4_-_89618928 2.420 NM_153757
NAP1L5
nucleosome assembly protein 1-like 5
chr14_-_103995336 2.415


chr10_+_85899184 2.411 NM_014394
GHITM
growth hormone inducible transmembrane protein
chr7_+_99933734 2.402 PILRB
paired immunoglobin-like type 2 receptor beta
chr8_+_59465818 2.387 SDCBP
syndecan binding protein (syntenin)
chr16_-_88772807 2.368 NM_178841
RNF166
ring finger protein 166
chr20_+_13202417 2.368 NM_080826
ISM1
isthmin 1 homolog (zebrafish)
chr7_+_44646220 2.363 OGDH
oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
chr12_+_132629014 2.352 NOC4L
nucleolar complex associated 4 homolog (S. cerevisiae)
chr6_+_15249034 2.337 JARID2
jumonji, AT rich interactive domain 2
chr7_+_44646180 2.329 OGDH
oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
chr16_+_88772884 2.327 NM_001012759
NM_001012762
CTU2

cytosolic thiouridylase subunit 2 homolog (S. pombe)

chr8_+_59465727 2.313 NM_001007067
NM_001007068
NM_001007069
NM_001007070
NM_005625
SDCBP




syndecan binding protein (syntenin)




chr1_-_15850718 2.308 CASP9
caspase 9, apoptosis-related cysteine peptidase
chr19_+_36103616 2.304 NM_015302
HAUS5
HAUS augmin-like complex, subunit 5
chr19_-_47734215 2.283 NM_014417
BBC3
BCL2 binding component 3
chr5_-_126366068 2.276 MARCH3
membrane-associated ring finger (C3HC4) 3
chr9_-_131644176 2.263 NM_001122671
NM_001122672
NM_004059
CCBL1


cysteine conjugate-beta lyase, cytoplasmic


chr22_+_41253055 2.262 NM_001204827
NM_022098
XPNPEP3

X-prolyl aminopeptidase (aminopeptidase P) 3, putative

chr19_-_55919324 2.261 NM_014501
UBE2S
ubiquitin-conjugating enzyme E2S
chr19_-_47617008 2.257 NM_015168
ZC3H4
zinc finger CCCH-type containing 4
chr14_+_61447949 2.244 SLC38A6
solute carrier family 38, member 6
chr7_-_36406446 2.243 NM_001199707
NM_001199706
NM_015314
NM_001199708
KIAA0895



KIAA0895



chr16_-_85045086 2.242 ZDHHC7
zinc finger, DHHC-type containing 7
chr10_-_60027630 2.236 NM_152230
IPMK
inositol polyphosphate multikinase
chr19_+_44100734 2.225 NM_001145347
ZNF576
zinc finger protein 576
chr17_+_685512 2.222 NM_018146
RNMTL1
RNA methyltransferase like 1
chr19_-_55918980 2.208 UBE2S
ubiquitin-conjugating enzyme E2S
chr19_+_39421562 2.172 NM_021107
NM_033363
MRPS12

mitochondrial ribosomal protein S12

chr16_+_89989686 2.163 NM_006086
TUBB3
tubulin, beta 3 class III
chr19_+_42580333 2.161 ZNF574
zinc finger protein 574
chr9_+_35538890 2.160 RUSC2
RUN and SH3 domain containing 2
chr4_+_113970784 2.149 NM_001148
NM_020977
ANK2

ankyrin 2, neuronal

chr21_-_43916298 2.143 NM_080860
RSPH1
radial spoke head 1 homolog (Chlamydomonas)
chr19_-_5720155 2.136 LONP1
lon peptidase 1, mitochondrial
chr12_+_110011499 2.122 NM_000431
NM_001114185
MVK

mevalonate kinase

chr3_+_183353355 2.118 NM_017644
KLHL24
kelch-like 24 (Drosophila)
chrX_+_7065820 2.116 STS
steroid sulfatase (microsomal), isozyme S
chr8_+_8559665 2.093 NM_194284
CLDN23
claudin 23
chr9_+_123605343 2.084 LOC253039
uncharacterized LOC253039
chr4_+_119512890 2.075 LOC729218
uncharacterized LOC729218
chr1_-_52344010 2.072 NRD1
nardilysin (N-arginine dibasic convertase)
chr19_+_42580275 2.063 NM_022752
ZNF574
zinc finger protein 574
chr6_-_7389941 2.060 NM_001170692
NM_001170693
NM_205864
CAGE1


cancer antigen 1


chr19_-_5720136 2.055 LONP1
lon peptidase 1, mitochondrial
chr11_+_117049387 2.054 SIDT2
SID1 transmembrane family, member 2
chr3_+_128598332 2.054 NM_014049
ACAD9
acyl-CoA dehydrogenase family, member 9
chr15_-_41047421 2.031 FAM82A2
family with sequence similarity 82, member A2
chr12_-_10766130 2.003 NM_018048
MAGOHB
mago-nashi homolog B (Drosophila)
chr9_-_79520878 1.989 NM_015225
PRUNE2
prune homolog 2 (Drosophila)
chr3_-_141944296 1.989 GK5
glycerol kinase 5 (putative)
chr19_-_39421080 1.978 NM_001145901
NM_017827
SARS2

seryl-tRNA synthetase 2, mitochondrial

chr1_+_85527992 1.973 NM_145172
WDR63
WD repeat domain 63
chr19_+_39936220 1.966 SUPT5H
suppressor of Ty 5 homolog (S. cerevisiae)
chr11_+_3818953 1.963 NM_001145438
PGAP2
post-GPI attachment to proteins 2
chr19_+_45349584 1.963 PVRL2
poliovirus receptor-related 2 (herpesvirus entry mediator B)

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
8.88 2.87e-03 GO:0042773 ATP synthesis coupled electron transport
8.88 2.87e-03 GO:0042775 mitochondrial ATP synthesis coupled electron transport
5.84 2.98e-03 GO:0022904 respiratory electron transport chain
7.97 6.67e-03 GO:0006119 oxidative phosphorylation
9.49 7.68e-03 GO:0006120 mitochondrial electron transport, NADH to ubiquinone
4.80 8.33e-03 GO:0045333 cellular respiration

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
1.18 3.39e-04 GO:0044424 intracellular part
1.93 1.40e-03 GO:0005739 mitochondrion
2.38 1.55e-03 GO:0044429 mitochondrial part
1.16 2.03e-03 GO:0005622 intracellular
1.22 8.31e-03 GO:0043231 intracellular membrane-bounded organelle
1.22 9.03e-03 GO:0043227 membrane-bounded organelle
7.51 2.70e-02 GO:0005747 mitochondrial respiratory chain complex I
7.51 2.70e-02 GO:0030964 NADH dehydrogenase complex
7.51 2.70e-02 GO:0045271 respiratory chain complex I
2.44 3.46e-02 GO:0031966 mitochondrial membrane
1.17 4.20e-02 GO:0043229 intracellular organelle
1.17 4.80e-02 GO:0043226 organelle
5.60 4.98e-02 GO:0005746 mitochondrial respiratory chain

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
7.92 2.57e-02 GO:0003954 NADH dehydrogenase activity
7.92 2.57e-02 GO:0008137 NADH dehydrogenase (ubiquinone) activity
7.92 2.57e-02 GO:0050136 NADH dehydrogenase (quinone) activity