Motif ID: CEBPA,B_DDIT3.p2

Z-value: 0.759


Transcription factors associated with CEBPA,B_DDIT3.p2:

Gene SymbolEntrez IDGene Name
CEBPA 1050 CCAAT/enhancer binding protein (C/EBP), alpha
CEBPB 1051 CCAAT/enhancer binding protein (C/EBP), beta
DDIT3 1649 DNA-damage-inducible transcript 3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
DDIT3hg19_v1_chr12_-_57914287_57914302-0.234.4e-02Click!
CEBPBhg19_v1_chr20_+_48807460_488078010.225.4e-02Click!
CEBPAhg19_v1_chr19_-_33793429_337934370.132.7e-01Click!


Activity profile for motif CEBPA,B_DDIT3.p2.

activity profile for motif CEBPA,B_DDIT3.p2


Sorted Z-values histogram for motif CEBPA,B_DDIT3.p2

Sorted Z-values for motif CEBPA,B_DDIT3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of CEBPA,B_DDIT3.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr17_-_39092714 20.226 KRT23
keratin 23 (histone deacetylase inducible)
chr19_-_44174497 5.456 NM_001005376
NM_001005377
NM_002659
PLAUR


plasminogen activator, urokinase receptor


chr12_-_53074172 5.177 NM_006121
KRT1
keratin 1
chr10_-_92680784 4.831 ANKRD1
ankyrin repeat domain 1 (cardiac muscle)
chr10_-_92681025 3.845 NM_014391
ANKRD1
ankyrin repeat domain 1 (cardiac muscle)
chr9_-_71590754 3.157


chr18_+_61637262 3.010 NM_001031848
NM_002640
NM_198833
SERPINB8


serpin peptidase inhibitor, clade B (ovalbumin), member 8


chrX_+_9431314 2.930 NM_001139466
NM_001139467
NM_001139468
TBL1X


transducin (beta)-like 1X-linked


chr1_-_230513390 2.888 NM_024554
PGBD5
piggyBac transposable element derived 5
chr19_-_49258646 2.861 NM_000148
FUT1
fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
chr12_-_52845862 2.779 NM_005555
KRT6B
keratin 6B
chr3_+_190105660 2.597 NM_006580
CLDN16
claudin 16
chr9_+_130860769 2.337 SLC25A25
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25
chr7_+_28338939 2.335 NM_182899
CREB5
cAMP responsive element binding protein 5
chr2_-_113594325 2.285 NM_000576
IL1B
interleukin 1, beta
chr4_+_108814419 2.194 NM_001136257
NM_152621
SGMS2

sphingomyelin synthase 2

chr12_-_63328857 1.979 PPM1H
protein phosphatase, Mg2+/Mn2+ dependent, 1H
chr1_+_111770280 1.656 NM_001025197
NM_004000
CHI3L2

chitinase 3-like 2

chr17_-_38978824 1.647 NM_000421
KRT10
keratin 10
chr2_+_234296799 1.641 NM_003648
DGKD
diacylglycerol kinase, delta 130kDa
chr4_-_10023094 1.555 NM_020041
SLC2A9
solute carrier family 2 (facilitated glucose transporter), member 9
chr12_-_52867521 1.533 NM_173086
KRT6C
keratin 6C
chr15_+_41245635 1.487 NM_001142776
NM_024111
CHAC1

ChaC, cation transport regulator homolog 1 (E. coli)

chr3_+_157154579 1.450 NM_002852
PTX3
pentraxin 3, long
chr6_+_158734902 1.421


chrX_-_133792497 1.401 NM_021796
PLAC1
placenta-specific 1
chr1_-_23342342 1.363 NM_001242521
LOC729059
uncharacterized LOC729059
chr16_+_27341305 1.318 IL4R
interleukin 4 receptor
chr12_+_54426831 1.314 NM_018953
HOXC5
homeobox C5
chr10_-_29923841 1.291


chr19_-_55580896 1.279 NM_138412
RDH13
retinol dehydrogenase 13 (all-trans/9-cis)
chr8_-_130799133 1.254 NM_031415
GSDMC
gasdermin C
chr3_-_42843217 1.247


chr19_+_49078992 1.220 NM_004605
SULT2B1
sulfotransferase family, cytosolic, 2B, member 1
chr19_+_47813074 1.195 NM_001736
C5AR1
complement component 5a receptor 1
chr4_-_15940362 1.190 NM_005130
FGFBP1
fibroblast growth factor binding protein 1
chr17_-_15523017 1.157 NM_006382
CDRT1
CMT1A duplicated region transcript 1
chr7_+_28725597 1.123 NM_001011666
CREB5
cAMP responsive element binding protein 5
chr5_+_167956545 1.123


chr12_+_65224214 1.096


chr18_-_61311465 1.074 NM_002974
SERPINB4
serpin peptidase inhibitor, clade B (ovalbumin), member 4
chr5_+_125758818 1.040 NM_001146320
NM_001146321
NM_023927
GRAMD3


GRAM domain containing 3


chr6_-_41254392 1.011 NM_001242589
NM_001242590
NM_018643
TREM1


triggering receptor expressed on myeloid cells 1


chr6_+_158734476 1.007 TULP4
tubby like protein 4
chr12_-_50595303 0.981 NM_001243775
LIMA1
LIM domain and actin binding 1
chr2_+_12858363 0.935


chr9_-_117156684 0.903 NM_030767
AKNA
AT-hook transcription factor
chr12_-_53045947 0.898 NM_000423
KRT2
keratin 2
chr5_-_94224601 0.862 MCTP1
multiple C2 domains, transmembrane 1
chr19_-_17516383 0.857 NM_004335
BST2
bone marrow stromal cell antigen 2
chr9_+_5510544 0.854 NM_025239
PDCD1LG2
programmed cell death 1 ligand 2
chr19_+_33864574 0.838 NM_001806
CEBPG
CCAAT/enhancer binding protein (C/EBP), gamma
chr20_+_361938 0.835 TRIB3
tribbles homolog 3 (Drosophila)
chr17_+_18647325 0.834 NM_031456
FBXW10
F-box and WD repeat domain containing 10
chr5_+_131409484 0.812 NM_000758
CSF2
colony stimulating factor 2 (granulocyte-macrophage)
chr1_-_31345361 0.803 SDC3
syndecan 3
chr10_-_1071797 0.800 NM_033261
IDI2
isopentenyl-diphosphate delta isomerase 2
chr9_-_95055913 0.797 IARS
isoleucyl-tRNA synthetase
chr8_+_124194751 0.790 NM_032899
NM_207006
FAM83A

family with sequence similarity 83, member A

chr8_+_24151579 0.784 NM_014265
NM_021777
ADAM28

ADAM metallopeptidase domain 28

chr9_-_95055966 0.783 NM_013417
IARS
isoleucyl-tRNA synthetase
chr9_-_95055986 0.782 IARS
isoleucyl-tRNA synthetase
chr20_+_54987167 0.769 NM_001164116
NM_001164114
NM_001164115
NM_020356
CASS4



Cas scaffolding protein family member 4



chr11_+_33363104 0.760 HIPK3
homeodomain interacting protein kinase 3
chr9_+_110045551 0.757 RAD23B
RAD23 homolog B (S. cerevisiae)
chr8_+_22019167 0.728 NM_001172357
NM_001172410
NM_003018
SFTPC


surfactant protein C


chr8_+_124194873 0.718 FAM83A
family with sequence similarity 83, member A
chr9_+_130860816 0.708 NM_052901
NM_001006643
SLC25A25

solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25

chr3_+_141043054 0.706 NM_001080412
ZBTB38
zinc finger and BTB domain containing 38
chr9_-_95055989 0.693 NM_002161
IARS
isoleucyl-tRNA synthetase
chr4_-_2935650 0.684 MFSD10
major facilitator superfamily domain containing 10
chr9_+_110045516 0.678 NM_002874
RAD23B
RAD23 homolog B (S. cerevisiae)
chr8_-_12973752 0.677 NM_001164271
DLC1
deleted in liver cancer 1
chr6_-_37225360 0.676 NM_145316
TMEM217
transmembrane protein 217
chr13_-_24007822 0.675 NM_014363
SACS
spastic ataxia of Charlevoix-Saguenay (sacsin)
chr5_+_154135029 0.665 LARP1
La ribonucleoprotein domain family, member 1
chr21_-_15918635 0.665 NM_022136
SAMSN1
SAM domain, SH3 domain and nuclear localization signals 1
chr9_+_80911990 0.662 NM_021154
NM_058179
PSAT1

phosphoserine aminotransferase 1

chr1_-_173020011 0.658 NM_005092
TNFSF18
tumor necrosis factor (ligand) superfamily, member 18
chr12_-_58160823 0.658 NM_000785
CYP27B1
cytochrome P450, family 27, subfamily B, polypeptide 1
chr3_+_12392993 0.654 NM_015869
PPARG
peroxisome proliferator-activated receptor gamma
chr10_+_86004808 0.645 NM_001012720
NM_001012722
NM_002921
RGR


retinal G protein coupled receptor


chr17_+_33448597 0.634 NM_017559
FNDC8
fibronectin type III domain containing 8
chr16_-_30787298 0.631


chr19_-_53233134 0.627 NM_030972
ZNF611
zinc finger protein 611
chr22_+_35779103 0.627 HMOX1
heme oxygenase (decycling) 1
chr15_-_72598655 0.608 NM_001172685
CELF6
CUGBP, Elav-like family member 6
chr9_+_137004913 0.600 NM_052821
WDR5
WD repeat domain 5
chr3_+_158787040 0.579 NM_001197113
NM_001197114
NM_001042705
NM_001042706
NM_001197100
IQCJ-SCHIP1

IQCJ


IQCJ-SCHIP1 readthrough

IQ motif containing J


chr7_-_104567089 0.570 LOC723809
uncharacterized LOC723809
chr19_-_3500937 0.569 NM_001145165
DOHH
deoxyhypusine hydroxylase/monooxygenase
chr9_+_110045565 0.560 RAD23B
RAD23 homolog B (S. cerevisiae)
chr11_-_121986800 0.559 NM_001001786
BLID
BH3-like motif containing, cell death inducer
chr16_+_56966025 0.559 HERPUD1
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
chr6_-_24489738 0.559 NM_177483
NM_001503
GPLD1

glycosylphosphatidylinositol specific phospholipase D1

chr10_+_121410751 0.549 NM_004281
BAG3
BCL2-associated athanogene 3
chr20_+_34995443 0.546 NM_014902
DLGAP4
discs, large (Drosophila) homolog-associated protein 4
chrX_+_96138906 0.542 NM_013347
RPA4
replication protein A4, 30kDa
chr9_+_125132823 0.541 PTGS1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr3_+_185080835 0.537 NM_004721
MAP3K13
mitogen-activated protein kinase kinase kinase 13
chr5_-_16738346 0.536 MYO10
myosin X
chr16_+_4430878 0.535 VASN
vasorin
chr6_+_167704802 0.534 NM_001143947
NM_018974
UNC93A

unc-93 homolog A (C. elegans)

chr12_-_121736110 0.520 NM_006549
NM_153499
NM_153500
NM_172214
NM_172215
NM_172216
CAMKK2





calcium/calmodulin-dependent protein kinase kinase 2, beta





chr19_+_33865429 0.513 NM_001252296
CEBPG
CCAAT/enhancer binding protein (C/EBP), gamma
chr20_-_47874147 0.512 ZNFX1
zinc finger, NFX1-type containing 1
chr10_-_116444374 0.506 NM_001003407
NM_001003408
ABLIM1

actin binding LIM protein 1

chr10_-_116444112 0.500 ABLIM1
actin binding LIM protein 1
chr2_+_11674241 0.496 NM_014668
GREB1
growth regulation by estrogen in breast cancer 1
chr5_-_176836488 0.494 F12
coagulation factor XII (Hageman factor)
chr4_-_2935851 0.492 NM_001120
MFSD10
major facilitator superfamily domain containing 10
chr21_-_11098819 0.489 NM_001187
NM_182484
NM_181704
NM_182481
NM_182482
BAGE
BAGE5
BAGE4
BAGE3
BAGE2
B melanoma antigen
B melanoma antigen family, member 5
B melanoma antigen family, member 4
B melanoma antigen family, member 3
B melanoma antigen family, member 2
chr5_-_66492574 0.489 NM_005582
CD180
CD180 molecule
chr10_+_69869249 0.487 NM_032578
MYPN
myopalladin
chr5_+_161275897 0.486 NM_001127646
GABRA1
gamma-aminobutyric acid (GABA) A receptor, alpha 1
chr5_-_131630939 0.482


chr3_+_48264836 0.479 NM_004345
CAMP
cathelicidin antimicrobial peptide
chr6_-_33548017 0.475 NM_001188
BAK1
BCL2-antagonist/killer 1
chr18_-_55289026 0.470 NM_004539
NARS
asparaginyl-tRNA synthetase
chr21_+_30400229 0.464 USP16
ubiquitin specific peptidase 16
chr17_-_77813049 0.461 NM_003655
CBX4
chromobox homolog 4
chr4_+_95376396 0.459 PDLIM5
PDZ and LIM domain 5
chr15_+_89182038 0.453 NM_002201
ISG20
interferon stimulated exonuclease gene 20kDa
chr12_+_75874512 0.445 NM_006851
GLIPR1
GLI pathogenesis-related 1
chr18_-_55289007 0.437 NARS
asparaginyl-tRNA synthetase
chr1_-_153283166 0.435 NM_052891
PGLYRP3
peptidoglycan recognition protein 3
chr16_+_67381252 0.435 NM_001161575
LRRC36
leucine rich repeat containing 36
chr20_+_361675 0.433 TRIB3
tribbles homolog 3 (Drosophila)
chr19_-_47128293 0.430 NM_000960
PTGIR
prostaglandin I2 (prostacyclin) receptor (IP)
chr1_-_153521717 0.425 NM_002960
S100A3
S100 calcium binding protein A3
chr6_-_42162693 0.423 NM_002098
GUCA1B
guanylate cyclase activator 1B (retina)
chr11_-_104972147 0.420 NM_001007232
NM_001223
NM_033292
NM_033293
NM_033294
NM_033295
CARD17
CASP1




caspase recruitment domain family, member 17
caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)




chr19_+_48949029 0.415 NM_031485
GRWD1
glutamate-rich WD repeat containing 1
chr11_+_63304272 0.415 NM_004585
RARRES3
retinoic acid receptor responder (tazarotene induced) 3
chr1_+_153330329 0.413 NM_002965
S100A9
S100 calcium binding protein A9
chr16_+_3405888 0.413 NM_012368
OR2C1
olfactory receptor, family 2, subfamily C, member 1
chr17_-_30228750 0.413 UTP6
UTP6, small subunit (SSU) processome component, homolog (yeast)
chr3_+_186435097 0.411 NM_000893
NM_001102416
NM_001166451
KNG1


kininogen 1


chr3_-_187420344 0.407 NM_001004312
RTP2
receptor (chemosensory) transporter protein 2
chr19_+_13250072 0.398 NACC1
nucleus accumbens associated 1, BEN and BTB (POZ) domain containing
chr9_+_684193 0.396


chrM_-_9203 0.393


chr9_-_130712866 0.393 NM_203305
FAM102A
family with sequence similarity 102, member A
chr11_-_66675334 0.379 NM_022172
PC
pyruvate carboxylase
chr3_+_156394452 0.371 NM_001184718
TIPARP
TCDD-inducible poly(ADP-ribose) polymerase
chr5_-_16742336 0.371 MYO10
myosin X
chr7_-_91763677 0.370 CYP51A1
cytochrome P450, family 51, subfamily A, polypeptide 1
chr2_+_237993954 0.367 NM_006710
NM_198189
COPS8

COP9 constitutive photomorphogenic homolog subunit 8 (Arabidopsis)

chr17_-_18177716 0.366 TOP3A
topoisomerase (DNA) III alpha
chr17_+_20771745 0.366


chr12_-_113841654 0.362 NM_006843
SDS
serine dehydratase
chr1_-_161207879 0.358 NM_001077469
NM_001077470
NM_001077471
NM_001077472
NM_001077473
NM_001077474
NM_001077475
NM_001077476
NM_001077477
NM_001077478
NM_001077479
NM_001077480
NM_001077481
NM_001077482
NM_005122
NR1I3














nuclear receptor subfamily 1, group I, member 3














chr16_-_21663962 0.355 NM_005849
IGSF6
immunoglobulin superfamily, member 6
chr6_+_30297087 0.354 NM_001199119
TRIM39-RPP21
TRIM39
TRIM39-RPP21 readthrough
tripartite motif containing 39
chr14_+_35514112 0.349 NM_001079519
FAM177A1
family with sequence similarity 177, member A1
chr9_+_125132785 0.348 PTGS1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr16_+_56815703 0.347 NM_001242795
NUP93
nucleoporin 93kDa
chr17_-_7166505 0.346 NM_001185022
CLDN7
claudin 7
chr12_-_57009361 0.345 BAZ2A
bromodomain adjacent to zinc finger domain, 2A
chr12_+_113344811 0.343 OAS1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr10_+_70980058 0.341 NM_025130
HKDC1
hexokinase domain containing 1
chr19_+_37180301 0.340 NM_152603
ZNF567
zinc finger protein 567
chr3_-_47957475 0.340


chr15_-_51386815 0.332 TNFAIP8L3
tumor necrosis factor, alpha-induced protein 8-like 3
chr10_-_50396380 0.329 NM_001010863
C10orf128
chromosome 10 open reading frame 128
chrX_-_40506800 0.328 NM_144970
CXorf38
chromosome X open reading frame 38
chr11_-_65547821 0.325 NM_138368
DKFZp761E198
adaptor protein 5
chr4_+_184020343 0.322 NM_024949
WWC2
WW and C2 domain containing 2
chr3_-_49399969 0.321 RHOA
ras homolog gene family, member A
chr14_+_29241989 0.320 C14orf23
chromosome 14 open reading frame 23
chr4_+_41700736 0.316 LIMCH1
LIM and calponin homology domains 1
chr21_-_47604360 0.315 NM_001142854
NM_032261
C21orf56

chromosome 21 open reading frame 56

chr9_+_116342939 0.308 NM_021106
RGS3
regulator of G-protein signaling 3
chr5_-_176836535 0.303 NM_000505
F12
coagulation factor XII (Hageman factor)
chr12_-_48744553 0.302 NM_001172681
NM_152320
ZNF641

zinc finger protein 641

chr20_+_24929904 0.301 CST7
cystatin F (leukocystatin)
chr5_+_125759076 0.300 GRAMD3
GRAM domain containing 3
chr6_+_12717036 0.296 NM_001242648
NM_030948
PHACTR1

phosphatase and actin regulator 1

chr2_-_38525527 0.293 ATL2
atlastin GTPase 2
chr3_+_159706622 0.292 NM_000882
IL12A
interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)
chr4_+_113739203 0.291 NM_001127493
ANK2
ankyrin 2, neuronal
chr22_+_45072687 0.291 NM_001017530
NM_001198721
NM_015366
PRR5


proline rich 5 (renal)


chr9_-_95186559 0.290 NM_005014
OMD
osteomodulin
chr4_-_71532341 0.287 NM_144646
IGJ
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr15_-_34212523 0.286


chr2_-_230933618 0.285 NM_152527
SLC16A14
solute carrier family 16, member 14 (monocarboxylic acid transporter 14)
chr1_-_154842725 0.284 NM_001204087
NM_002249
KCNN3

potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3

chr3_+_186330859 0.280 AHSG
alpha-2-HS-glycoprotein
chr16_+_75252882 0.275 NM_001906
CTRB1
chymotrypsinogen B1
chr11_+_18287807 0.274 NM_000331
NM_001178006
NM_199161
SAA1


serum amyloid A1


chr7_-_91764036 0.273 NM_001146152
CYP51A1
cytochrome P450, family 51, subfamily A, polypeptide 1
chr18_+_29598444 0.273 NM_017831
RNF125
ring finger protein 125
chr4_+_146031528 0.272 ABCE1
ATP-binding cassette, sub-family E (OABP), member 1
chr10_+_135160843 0.272 NM_001145201
NM_145202
PRAP1

proline-rich acidic protein 1

chr11_-_102668822 0.270 MMP1
matrix metallopeptidase 1 (interstitial collagenase)
chr1_+_40859016 0.269 NM_001198979
SMAP2
small ArfGAP2
chr5_+_132009372 0.269 NM_000589
NM_172348
IL4

interleukin 4

chr3_+_186330711 0.268 AHSG
alpha-2-HS-glycoprotein
chr6_-_11111955 0.268 NM_207582
ERVFRD-1
endogenous retrovirus group FRD, member 1
chr13_+_29598746 0.265 NM_001033602
MTUS2
microtubule associated tumor suppressor candidate 2

Gene Ontology Analysis

Nothing significant found in process category.

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
14.72 1.04e-03 GO:0005882 intermediate filament
24.26 1.09e-03 GO:0045095 keratin filament
12.76 2.06e-03 GO:0045111 intermediate filament cytoskeleton

Nothing significant found in function category.