Motif ID: CACAGUG

Z-value: 1.195


Mature miRNA associated with seed CACAGUG:

NamemiRBase Accession
hsa-miR-128 MIMAT0000424



Activity profile for motif CACAGUG.

activity profile for motif CACAGUG


Sorted Z-values histogram for motif CACAGUG

Sorted Z-values for motif CACAGUG



Network of associatons between targets according to the STRING database.



First level regulatory network of CACAGUG

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_+_156887026 15.879 NM_001099287
NM_001172292
NIPAL4

NIPA-like domain containing 4

chr8_-_22550708 13.239 NM_004430
EGR3
early growth response 3
chr8_-_22549901 13.226 NM_001199880
EGR3
early growth response 3
chr8_-_22550057 12.857 NM_001199881
EGR3
early growth response 3
chr6_+_136172802 12.677 NM_018945
PDE7B
phosphodiesterase 7B
chr16_-_4588738 12.339 NM_001199055
NM_001199056
NM_013399
C16orf5


chromosome 16 open reading frame 5


chr16_-_4588379 10.907 NM_001199054
C16orf5
chromosome 16 open reading frame 5
chrX_+_102632108 10.592 NM_014380
NGFRAP1
nerve growth factor receptor (TNFRSF16) associated protein 1
chrX_+_102631267 10.436 NM_206915
NM_206917
NGFRAP1

nerve growth factor receptor (TNFRSF16) associated protein 1

chr2_+_30454396 9.489 NM_030915
LBH
limb bud and heart development homolog (mouse)
chr11_+_118401755 8.190 NM_001144034
NM_001144035
NM_001144036
NM_001144037
NM_001144038
NM_032780
TMEM25





transmembrane protein 25





chr19_+_15218141 7.991 NM_033025
SYDE1
synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
chr5_-_111093251 7.901 NM_001142479
NM_001142480
NM_001142478
C5orf13


chromosome 5 open reading frame 13


chr19_+_45971249 7.666 NM_001114171
NM_006732
FOSB

FBJ murine osteosarcoma viral oncogene homolog B

chr5_-_111312522 7.460 NM_001142474
NM_001142475
C5orf13

chromosome 5 open reading frame 13

chr5_-_115910406 7.383 NM_020796
SEMA6A
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr5_-_111093792 7.367 NM_001142477
NM_001142476
C5orf13

chromosome 5 open reading frame 13

chr5_-_111092918 7.178 NM_004772
C5orf13
chromosome 5 open reading frame 13
chr5_-_111093030 6.881 NM_001142482
NM_001142481
C5orf13

chromosome 5 open reading frame 13

chr17_-_78450247 6.810 NM_002522
NPTX1
neuronal pentraxin I
chr1_-_108507474 6.762 NM_006113
VAV3
vav 3 guanine nucleotide exchange factor
chr6_+_13925097 6.355 NM_001165032
NM_152737
RNF182

ring finger protein 182

chr1_+_160370363 6.127 NM_020335
VANGL2
vang-like 2 (van gogh, Drosophila)
chr15_+_48010685 5.869 NM_020858
NM_024966
NM_153616
NM_153617
NM_153618
NM_153619
SEMA6D





sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D





chr12_-_26277807 5.724 NM_030762
BHLHE41
basic helix-loop-helix family, member e41
chr1_-_166944504 5.525 NM_199351
ILDR2
immunoglobulin-like domain containing receptor 2
chr5_-_57755787 5.443 NM_001252226
NM_006622
PLK2

polo-like kinase 2

chr6_+_13925423 5.244 NM_001165033
RNF182
ring finger protein 182
chr1_-_108231122 5.203 NM_001079874
VAV3
vav 3 guanine nucleotide exchange factor
chr15_+_47476225 5.173 NM_001198999
SEMA6D
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
chr22_-_28197469 5.117 NM_002430
MN1
meningioma (disrupted in balanced translocation) 1
chr11_+_121322848 5.012 NM_003105
SORL1
sortilin-related receptor, L(DLR class) A repeats containing
chr5_-_124080773 4.908 NM_020747
ZNF608
zinc finger protein 608
chr11_+_14665268 4.822 NM_000922
PDE3B
phosphodiesterase 3B, cGMP-inhibited
chr15_+_98503907 4.788 NM_183376
ARRDC4
arrestin domain containing 4
chr17_+_57408907 4.615 NM_001005404
YPEL2
yippee-like 2 (Drosophila)
chr14_+_92790151 4.459 NM_153646
SLC24A4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr12_+_121078421 4.421 NM_001033677
CABP1
calcium binding protein 1
chr6_+_126240369 4.411 NM_001199622
NCOA7
nuclear receptor coactivator 7
chr5_+_132149022 4.184 NM_175873
ANKRD43
ankyrin repeat domain 43
chr14_+_56584854 4.150 NM_021255
PELI2
pellino homolog 2 (Drosophila)
chr8_+_79428335 4.145 NM_006823
NM_181839
PKIA

protein kinase (cAMP-dependent, catalytic) inhibitor alpha

chr6_+_126111782 4.135 NM_001122842
NM_001199621
NM_181782
NCOA7


nuclear receptor coactivator 7


chr5_-_139726173 3.999 NM_001945
HBEGF
heparin-binding EGF-like growth factor
chr10_+_70320044 3.980 NM_030625
TET1
tet methylcytosine dioxygenase 1
chr10_+_18429605 3.921 NM_201593
NM_201596
NM_201597
NM_001167945
NM_201571
NM_201572
CACNB2





calcium channel, voltage-dependent, beta 2 subunit





chr5_-_111091947 3.759 NM_001142483
C5orf13
chromosome 5 open reading frame 13
chr22_-_39240016 3.647 NM_014293
NPTXR
neuronal pentraxin receptor
chr8_-_41754244 3.641 NM_001142446
ANK1
ankyrin 1, erythrocytic
chr19_+_51815095 3.585 NM_001101372
IGLON5
IgLON family member 5
chr1_-_99470177 3.573 NM_001010861
NM_001037317
LPPR5

lipid phosphate phosphatase-related protein type 5

chr5_+_7396030 3.535 NM_020546
ADCY2
adenylate cyclase 2 (brain)
chr14_+_92789536 3.509 NM_153647
SLC24A4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr4_+_26862312 3.508 NM_001169117
NM_001169118
NM_020860
STIM2


stromal interaction molecule 2


chr17_+_11144739 3.439 NM_001173461
NM_001173462
NM_207386
SHISA6


shisa homolog 6 (Xenopus laevis)


chr6_-_3456734 3.428 NM_015482
SLC22A23
solute carrier family 22, member 23
chr19_+_57154526 3.428 NM_001193628
LOC147670
uncharacterized LOC147670
chr3_-_39195101 3.422 NM_033027
CSRNP1
cysteine-serine-rich nuclear protein 1
chr20_+_49348050 3.333 NM_032521
PARD6B
par-6 partitioning defective 6 homolog beta (C. elegans)
chr16_-_89007605 3.303 NM_175931
CBFA2T3
core-binding factor, runt domain, alpha subunit 2; translocated to, 3
chr6_-_119399759 3.283 NM_024581
FAM184A
family with sequence similarity 184, member A
chr9_+_112403067 3.242 NM_001037293
PALM2
paralemmin 2
chr21_+_33245304 3.231 NM_014586
HUNK
hormonally up-regulated Neu-associated kinase
chr8_-_41655139 3.196 NM_000037
NM_020475
NM_020476
NM_020477
ANK1



ankyrin 1, erythrocytic



chr1_+_228194722 3.177 NM_033131
WNT3A
wingless-type MMTV integration site family, member 3A
chr18_+_55102777 3.153 NM_004852
ONECUT2
one cut homeobox 2
chr1_+_2985730 3.147 NM_022114
NM_199454
PRDM16

PR domain containing 16

chr2_-_100721792 3.141 NM_001025108
AFF3
AF4/FMR2 family, member 3
chr3_-_64211111 3.119 NM_198859
PRICKLE2
prickle homolog 2 (Drosophila)
chr7_-_27239724 3.112 NM_000522
HOXA13
homeobox A13
chr21_-_40033617 3.063 NM_001243432
NM_001136154
NM_004449
ERG


v-ets erythroblastosis virus E26 oncogene homolog (avian)


chr2_-_100758970 2.966 NM_002285
AFF3
AF4/FMR2 family, member 3
chr20_+_10199455 2.953 NM_003081
NM_130811
SNAP25

synaptosomal-associated protein, 25kDa

chr17_-_41985112 2.949 NM_005374
MPP2
membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
chr12_-_123451031 2.943 NM_001243013
NM_001243014
NM_019624
NM_019625
NM_203444
ABCB9




ATP-binding cassette, sub-family B (MDR/TAP), member 9




chr6_-_166075520 2.913 NM_006661
NM_001130690
PDE10A

phosphodiesterase 10A

chr6_+_133562488 2.898 NM_004100
NM_172103
NM_172105
EYA4


eyes absent homolog 4 (Drosophila)


chr10_+_112257624 2.880 NM_004419
DUSP5
dual specificity phosphatase 5
chr14_-_88789531 2.871 NM_138317
KCNK10
potassium channel, subfamily K, member 10
chr5_+_50678957 2.870 NM_002202
ISL1
ISL LIM homeobox 1
chr13_+_113623496 2.833 NM_001112732
MCF2L
MCF.2 cell line derived transforming sequence-like
chr12_+_121088370 2.810 NM_004276
NM_031205
CABP1

calcium binding protein 1

chr9_+_34958171 2.796 NM_015297
KIAA1045
KIAA1045
chr1_-_35370983 2.796 NM_001080418
DLGAP3
discs, large (Drosophila) homolog-associated protein 3
chrX_-_54384436 2.765 NM_001002838
NM_020922
WNK3

WNK lysine deficient protein kinase 3

chr3_-_170303774 2.717 NM_020949
SLC7A14
solute carrier family 7 (orphan transporter), member 14
chr4_-_42154894 2.708 NM_001159547
NM_207406
BEND4

BEN domain containing 4

chr1_+_204913353 2.705 NM_001160331
NFASC
neurofascin
chr9_-_107690526 2.703 NM_005502
ABCA1
ATP-binding cassette, sub-family A (ABC1), member 1
chr2_+_43864433 2.689 NM_172069
PLEKHH2
pleckstrin homology domain containing, family H (with MyTH4 domain) member 2
chr14_+_92788924 2.680 NM_153648
SLC24A4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr6_+_13924676 2.677 NM_001165034
RNF182
ring finger protein 182
chr12_+_79257772 2.676 NM_001135805
SYT1
synaptotagmin I
chr13_-_49001042 2.664 NM_001162497
LPAR6
lysophosphatidic acid receptor 6
chr6_+_126102278 2.657 NM_001199619
NM_001199620
NCOA7

nuclear receptor coactivator 7

chr11_-_45687135 2.638 NM_003654
CHST1
carbohydrate (keratan sulfate Gal-6) sulfotransferase 1
chr9_+_137533643 2.635 NM_000093
COL5A1
collagen, type V, alpha 1
chr12_+_132379262 2.631 NM_003565
ULK1
unc-51-like kinase 1 (C. elegans)
chr13_-_49018802 2.579 NM_005767
LPAR6
lysophosphatidic acid receptor 6
chr7_-_103629962 2.575 NM_005045
NM_173054
RELN

reelin

chr6_-_153452383 2.571 NM_012419
RGS17
regulator of G-protein signaling 17
chr18_+_49866541 2.567 NM_005215
DCC
deleted in colorectal carcinoma
chr17_+_47572592 2.557 NM_002507
NGFR
nerve growth factor receptor
chr7_+_155250705 2.542 NM_001427
EN2
engrailed homeobox 2
chr14_+_72399149 2.535 NM_001204424
RGS6
regulator of G-protein signaling 6
chr10_+_18549583 2.532 NM_000724
CACNB2
calcium channel, voltage-dependent, beta 2 subunit
chr11_+_34642587 2.528 NM_001206615
NM_012153
EHF

ets homologous factor

chr3_+_183993798 2.523 NM_001037324
NM_001100120
NM_001100121
ECE2


endothelin converting enzyme 2


chr14_+_72398816 2.505 NM_001204423
RGS6
regulator of G-protein signaling 6
chr2_-_27718098 2.477 NM_022823
FNDC4
fibronectin type III domain containing 4
chr7_-_37393271 2.425 NM_001206482
ELMO1
engulfment and cell motility 1
chr19_-_13617037 2.404 NM_000068
NM_001127221
NM_001127222
NM_001174080
NM_023035
CACNA1A




calcium channel, voltage-dependent, P/Q type, alpha 1A subunit




chr9_+_118916069 2.403 NM_002581
PAPPA
pregnancy-associated plasma protein A, pappalysin 1
chr16_+_66878281 2.401 NM_005182
CA7
carbonic anhydrase VII
chr14_-_39901619 2.399 NM_203301
FBXO33
F-box protein 33
chr3_-_155421996 2.383 NM_014996
PLCH1
phospholipase C, eta 1
chr3_-_49203769 2.372 NM_022903
CCDC71
coiled-coil domain containing 71
chr1_-_51810693 2.370 NM_001144832
TTC39A
tetratricopeptide repeat domain 39A
chr11_-_18813127 2.367 NM_001039970
NM_006906
NM_032781
PTPN5


protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched)


chr15_+_81071708 2.350 NM_018689
KIAA1199
KIAA1199
chrX_+_105066531 2.334 NM_198465
NRK
Nik related kinase
chr22_+_41957011 2.315 NM_014460
CSDC2
cold shock domain containing C2, RNA binding
chr11_-_88781039 2.297 NM_001143831
GRM5
glutamate receptor, metabotropic 5
chr15_-_73661604 2.290 NM_005477
HCN4
hyperpolarization activated cyclic nucleotide-gated potassium channel 4
chr16_-_89043215 2.289 NM_005187
CBFA2T3
core-binding factor, runt domain, alpha subunit 2; translocated to, 3
chr4_-_82393025 2.272 NM_152545
RASGEF1B
RasGEF domain family, member 1B
chr19_-_8675559 2.270 NM_030957
ADAMTS10
ADAM metallopeptidase with thrombospondin type 1 motif, 10
chr16_+_66878840 2.260 NM_001014435
CA7
carbonic anhydrase VII
chr5_-_160279045 2.255 NM_025153
ATP10B
ATPase, class V, type 10B
chr7_-_28998028 2.248 NM_014817
TRIL
TLR4 interactor with leucine-rich repeats
chr10_+_18629613 2.244 NM_201590
CACNB2
calcium channel, voltage-dependent, beta 2 subunit
chr6_+_391738 2.216 NM_001195286
NM_002460
IRF4

interferon regulatory factor 4

chr4_-_13546037 2.216 NM_001189
NKX3-2
NK3 homeobox 2
chr2_+_5832778 2.215 NM_003108
SOX11
SRY (sex determining region Y)-box 11
chr20_+_24449834 2.210 NM_024893
SYNDIG1
synapse differentiation inducing 1
chr3_-_124774735 2.208 NM_020733
HEG1
HEG homolog 1 (zebrafish)
chr1_+_13910251 2.168 NM_006474
NM_198389
PDPN

podoplanin

chr21_-_39870303 2.155 NM_001136155
NM_182918
ERG

v-ets erythroblastosis virus E26 oncogene homolog (avian)

chr4_-_107957452 2.125 NM_014421
DKK2
dickkopf 2 homolog (Xenopus laevis)
chr7_-_37488554 2.124 NM_014800
ELMO1
engulfment and cell motility 1
chr8_+_40010986 2.122 NM_020130
C8orf4
chromosome 8 open reading frame 4
chr10_+_18689512 2.119 NM_201570
CACNB2
calcium channel, voltage-dependent, beta 2 subunit
chr2_+_210636700 2.107 NM_032504
NM_182587
UNC80

unc-80 homolog (C. elegans)

chrX_+_122318095 2.075 NM_000828
NM_007325
GRIA3

glutamate receptor, ionotrophic, AMPA 3

chr20_+_2673193 2.069 NM_001110514
EBF4
early B-cell factor 4
chr4_-_153303663 2.050 NM_001013415
FBXW7
F-box and WD repeat domain containing 7
chr15_+_29213839 2.041 NM_001130414
NM_005503
APBA2

amyloid beta (A4) precursor protein-binding, family A, member 2

chr5_+_172068188 2.013 NM_001142651
NEURL1B
neuralized homolog 1B (Drosophila)
chr17_+_42385780 2.013 NM_001144825
NM_001144826
NM_006695
RUNDC3A


RUN domain containing 3A


chr12_+_113495661 2.006 NM_004416
DTX1
deltex homolog 1 (Drosophila)
chr6_-_149806116 1.997 NM_207360
ZC3H12D
zinc finger CCCH-type containing 12D
chr2_+_31456879 1.987 NM_014600
EHD3
EH-domain containing 3
chr1_-_1535446 1.979 NM_001242659
LOC643988
uncharacterized LOC643988
chr4_+_81952118 1.954 NM_001201
BMP3
bone morphogenetic protein 3
chr1_+_28585959 1.951 NM_031459
SESN2
sestrin 2
chr13_-_48987652 1.933 NM_001162498
LPAR6
lysophosphatidic acid receptor 6
chr1_+_215256559 1.919 NM_001017425
NM_014217
KCNK2

potassium channel, subfamily K, member 2

chr18_-_31803514 1.916 NM_001198546
NM_001198548
NM_003787
NOL4


nucleolar protein 4


chr3_+_13590624 1.914 NM_001004019
NM_001998
FBLN2

fibulin 2

chr10_+_43572500 1.894 NM_020630
NM_020975
RET

ret proto-oncogene

chr1_+_204797774 1.893 NM_001005388
NM_001005389
NM_001160332
NM_001160333
NM_015090
NFASC




neurofascin




chr13_-_45775174 1.892 NM_198404
KCTD4
potassium channel tetramerisation domain containing 4
chr10_-_94003002 1.886 NM_001178137
CPEB3
cytoplasmic polyadenylation element binding protein 3
chr8_-_41522724 1.866 NM_001142445
NM_020478
NM_020480
ANK1


ankyrin 1, erythrocytic


chr12_+_20522178 1.858 NM_000921
PDE3A
phosphodiesterase 3A, cGMP-inhibited
chr9_-_23821842 1.857 NM_001171195
ELAVL2
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr12_-_109747024 1.839 NM_213596
FOXN4
forkhead box N4
chr7_-_37488894 1.836 NM_001206480
ELMO1
engulfment and cell motility 1
chr2_+_232260334 1.835 NM_145236
B3GNT7
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7
chr3_-_155394104 1.820 NM_001130960
NM_001130961
PLCH1

phospholipase C, eta 1

chr14_-_88737160 1.818 NM_138318
KCNK10
potassium channel, subfamily K, member 10
chr12_+_79439432 1.807 NM_001135806
SYT1
synaptotagmin I
chr22_-_29075708 1.792 NM_001145418
TTC28
tetratricopeptide repeat domain 28
chr2_-_227663454 1.789 NM_005544
IRS1
insulin receptor substrate 1
chr9_-_110252045 1.769 NM_004235
KLF4
Kruppel-like factor 4 (gut)
chr15_-_63674074 1.767 NM_001218
NM_206925
CA12

carbonic anhydrase XII

chr9_-_23821477 1.763 NM_001171197
ELAVL2
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr8_+_16884745 1.761 NM_181723
EFHA2
EF-hand domain family, member A2
chr1_-_184006828 1.758 NM_015101
GLT25D2
glycosyltransferase 25 domain containing 2
chr6_-_33267128 1.757 NM_001243738
NM_004761
RGL2

ral guanine nucleotide dissociation stimulator-like 2

chr1_+_221052735 1.744 NM_021958
HLX
H2.0-like homeobox
chr14_-_89883306 1.742 NM_005197
FOXN3
forkhead box N3
chr12_+_79258448 1.729 NM_005639
SYT1
synaptotagmin I
chr6_+_111408780 1.718 NM_018593
SLC16A10
solute carrier family 16, member 10 (aromatic amino acid transporter)
chr15_+_76352270 1.717 NM_152335
C15orf27
chromosome 15 open reading frame 27
chr16_-_4292052 1.713 NM_001098814
SRL
sarcalumenin
chr4_-_153273683 1.699 NM_018315
FBXW7
F-box and WD repeat domain containing 7
chr12_-_82153092 1.693 NM_003625
PPFIA2
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2
chr19_+_19322763 1.681 NM_004386
NCAN
neurocan
chr2_-_158454025 1.672 NM_001111031
ACVR1C
activin A receptor, type IC
chr14_-_88793250 1.670 NM_021161
KCNK10
potassium channel, subfamily K, member 10
chr6_-_56112315 1.665 NM_030820
COL21A1
collagen, type XXI, alpha 1
chr9_-_130533509 1.664 NM_001252334
NM_005489
SH2D3C

SH2 domain containing 3C

chr2_-_109605668 1.662 NM_022336
EDAR
ectodysplasin A receptor
chr1_-_202612580 1.661 NM_001136504
SYT2
synaptotagmin II
chr6_+_118228688 1.661 NM_001029858
SLC35F1
solute carrier family 35, member F1
chr10_+_104503724 1.660 NM_001083913
C10orf26
chromosome 10 open reading frame 26
chr9_-_101470836 1.655 NM_005458
GABBR2
gamma-aminobutyric acid (GABA) B receptor, 2
chr5_-_157002739 1.651 NM_033274
ADAM19
ADAM metallopeptidase domain 19
chr20_-_30795346 1.643 NM_002657
PLAGL2
pleiomorphic adenoma gene-like 2

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
2.24 7.92e-13 GO:0007275 multicellular organismal development
2.12 4.48e-12 GO:0032502 developmental process
3.55 2.74e-09 GO:0022008 neurogenesis
1.77 3.17e-09 GO:0032501 multicellular organismal process
2.51 3.48e-09 GO:0030154 cell differentiation
2.48 3.70e-09 GO:0048869 cellular developmental process
2.11 5.88e-09 GO:0048856 anatomical structure development
3.58 8.34e-09 GO:0048699 generation of neurons
3.95 8.60e-09 GO:0030182 neuron differentiation
2.75 4.41e-08 GO:0007399 nervous system development
4.07 1.64e-07 GO:0048666 neuron development
2.09 2.39e-07 GO:0048731 system development
3.26 2.40e-07 GO:0048468 cell development
1.80 1.24e-05 GO:0023052 signaling
1.43 2.59e-05 GO:0065007 biological regulation
1.48 3.03e-05 GO:0050794 regulation of cellular process
2.40 5.30e-05 GO:0009653 anatomical structure morphogenesis
3.74 7.08e-05 GO:0031175 neuron projection development
1.44 8.71e-05 GO:0050789 regulation of biological process
3.68 9.76e-05 GO:0048858 cell projection morphogenesis
3.64 1.14e-04 GO:0032990 cell part morphogenesis
3.29 1.23e-04 GO:0030030 cell projection organization
3.38 1.31e-04 GO:0000902 cell morphogenesis
3.84 1.80e-04 GO:0048667 cell morphogenesis involved in neuron differentiation
3.77 2.41e-04 GO:0048812 neuron projection morphogenesis
3.21 3.51e-04 GO:0032989 cellular component morphogenesis
3.54 3.61e-04 GO:0000904 cell morphogenesis involved in differentiation
3.79 4.43e-04 GO:0007409 axonogenesis
2.87 1.03e-03 GO:0007267 cell-cell signaling
2.03 2.43e-03 GO:0048513 organ development
3.29 6.89e-03 GO:0048646 anatomical structure formation involved in morphogenesis
2.40 9.12e-03 GO:0007154 cell communication
1.65 9.59e-03 GO:0007165 signal transduction
3.29 1.22e-02 GO:0007268 synaptic transmission
3.09 1.66e-02 GO:0019226 transmission of nerve impulse
3.09 1.66e-02 GO:0035637 multicellular organismal signaling
2.00 2.19e-02 GO:0023051 regulation of signaling
3.56 2.69e-02 GO:0007411 axon guidance
2.56 2.91e-02 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
5.13 3.05e-02 GO:0045165 cell fate commitment
2.62 4.59e-02 GO:0045595 regulation of cell differentiation
2.48 4.72e-02 GO:0051173 positive regulation of nitrogen compound metabolic process

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
3.76 6.96e-05 GO:0045202 synapse
4.30 8.16e-05 GO:0044456 synapse part
3.62 2.42e-04 GO:0043005 neuron projection
54.60 1.57e-03 GO:0042583 chromaffin granule
54.60 1.57e-03 GO:0042584 chromaffin granule membrane
7.11 2.62e-03 GO:0030139 endocytic vesicle
9.71 5.12e-03 GO:0030666 endocytic vesicle membrane
72.79 2.91e-02 GO:0032281 alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex
4.43 3.29e-02 GO:0045211 postsynaptic membrane

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
22.75 4.29e-04 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity
15.17 3.81e-03 GO:0004114 3',5'-cyclic-nucleotide phosphodiesterase activity
14.56 4.71e-03 GO:0004112 cyclic-nucleotide phosphodiesterase activity
2.28 7.57e-03 GO:0001071 nucleic acid binding transcription factor activity
2.28 7.57e-03 GO:0003700 sequence-specific DNA binding transcription factor activity
13.00 8.43e-03 GO:0008066 glutamate receptor activity
19.41 9.94e-03 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity
17.13 1.70e-02 GO:0030552 cAMP binding
72.79 4.42e-02 GO:0004119 cGMP-inhibited cyclic-nucleotide phosphodiesterase activity
5.79 4.95e-02 GO:0008081 phosphoric diester hydrolase activity