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Motif ID: ATF5_CREB3.p2

Z-value: 2.058

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr20_+_33146500	34.082	NM_032514	MAP1LC3A	microtubule-associated protein 1 light chain 3 alpha
chr9_+_102584136	32.397	NM_006981 NM_173199 NM_173200	NR4A3	nuclear receptor subfamily 4, group A, member 3
chr12_+_52445185	26.244	NM_002135 NM_173157	NR4A1	nuclear receptor subfamily 4, group A, member 1
chr17_+_38171613	19.159	NM_000759 NM_001178147 NM_172219 NM_172220	CSF3	colony stimulating factor 3 (granulocyte)
chr10_+_112257624	16.479	NM_004419	DUSP5	dual specificity phosphatase 5
chr2_-_73520448	15.583	NM_001965	EGR4	early growth response 4
chr4_+_75480628	15.210	NM_001657	AREG	amphiregulin
chr4_+_75310852	15.079	NM_001657	AREG	amphiregulin
chr22_+_38597938	11.565	NM_001161572 NM_001161574 NM_012323	MAFF	v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian)
chr8_-_22550708	11.109	NM_004430	EGR3	early growth response 3
chr1_+_85527992	10.862	NM_145172	WDR63	WD repeat domain 63
chr22_+_38598065	10.592		MAFF	v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian)
chr7_+_28448970	10.434		LOC401317	uncharacterized LOC401317
chr3_+_141087298	9.409		ZBTB38	zinc finger and BTB domain containing 38
chr1_-_186649421	9.192	NM_000963	PTGS2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
chr2_-_216300770	8.545	NM_002026 NM_054034 NM_212474 NM_212476 NM_212478 NM_212482	FN1	fibronectin 1
chr8_-_29207795	8.326	NM_001394	DUSP4	dual specificity phosphatase 4
chr19_+_16187047	8.229	NM_003290	TPM4	tropomyosin 4
chr1_-_16482426	7.924	NM_004431	EPHA2	EPH receptor A2
chr19_+_16187306	7.840		TPM4	tropomyosin 4
chr19_+_16187315	7.801		TPM4	tropomyosin 4
chr19_+_16187266	7.731		TPM4	tropomyosin 4
chr11_-_65667858	7.415		FOSL1	FOS-like antigen 1
chr3_+_99357439	7.267	NM_001850 NM_020351	COL8A1	collagen, type VIII, alpha 1
chr2_-_157189040	7.193	NM_006186	NR4A2	nuclear receptor subfamily 4, group A, member 2
chr11_-_65667860	7.154	NM_005438	FOSL1	FOS-like antigen 1
chr11_-_65667809	6.984		FOSL1	FOS-like antigen 1
chr2_-_192015706	6.810		STAT4	signal transducer and activator of transcription 4
chr2_-_192015733	6.759		STAT4	signal transducer and activator of transcription 4
chr2_-_216300444	6.743		FN1	fibronectin 1
chr12_-_123380608	6.462
chr8_-_11324184	6.426	NM_053279	FAM167A	family with sequence similarity 167, member A
chr10_+_70847857	6.228		SRGN	serglycin
chr2_-_192015751	6.152		STAT4	signal transducer and activator of transcription 4
chr11_-_67141008	6.133	NM_013246	CLCF1	cardiotrophin-like cytokine factor 1
chr12_-_121476770	6.021	NM_003733 NM_198213	OASL	2'-5'-oligoadenylate synthetase-like
chr19_+_16254454	5.886		HSH2D	hematopoietic SH2 domain containing
chr8_-_22550456	5.873		EGR3	early growth response 3
chr12_-_49318663	5.835	NM_001143781	FKBP11	FK506 binding protein 11, 19 kDa
chr6_+_15249034	5.754		JARID2	jumonji, AT rich interactive domain 2
chr11_-_1593149	5.733	NM_004420	DUSP8	dual specificity phosphatase 8
chr11_+_117070039	5.709	NM_001001522 NM_003186	TAGLN	transgelin
chr1_+_45266035	5.706	NM_004073	PLK3	polo-like kinase 3
chr3_-_16306283	5.657	NM_001047434 NM_206831	DPH3	DPH3, KTI11 homolog (S. cerevisiae)
chr4_-_186456580	5.573	NM_001114107 NM_014476	PDLIM3	PDZ and LIM domain 3
chr1_+_212782103	5.556		ATF3	activating transcription factor 3
chr19_-_55574434	5.531	NM_001145971	RDH13	retinol dehydrogenase 13 (all-trans/9-cis)
chr2_-_224467049	5.507		SCG2	secretogranin II
chr11_+_73087396	5.387	NM_152222	RELT	RELT tumor necrosis factor receptor
chr3_+_111578026	5.378	NM_001134438 NM_145753	PHLDB2	pleckstrin homology-like domain, family B, member 2
chr1_+_45266048	5.364		PLK3	polo-like kinase 3
chr21_-_44846927	5.322	NM_173354	SIK1	salt-inducible kinase 1
chr19_+_49375677	5.290		PPP1R15A	protein phosphatase 1, regulatory subunit 15A
chr10_+_104154228	5.282	NM_001077493 NM_001077494	NFKB2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr12_-_49319211	5.265	NM_001143782 NM_016594	FKBP11	FK506 binding protein 11, 19 kDa
chr12_-_123380628	5.244		VPS37B	vacuolar protein sorting 37 homolog B (S. cerevisiae)
chr19_+_49375679	5.234		PPP1R15A	protein phosphatase 1, regulatory subunit 15A
chr4_+_75174189	5.208	NM_001013442	EPGN	epithelial mitogen homolog (mouse)
chr1_+_212781969	5.205	NM_001040619 NM_001206484 NM_001206488 NM_001674	ATF3	activating transcription factor 3
chr14_-_38064440	5.165	NM_004496	FOXA1	forkhead box A1
chr8_+_126442557	5.160	NM_025195	TRIB1	tribbles homolog 1 (Drosophila)
chr2_+_75061234	5.144		HK2	hexokinase 2
chr1_+_86046434	5.035	NM_001554	CYR61	cysteine-rich, angiogenic inducer, 61
chr17_-_46703613	5.003	NM_024017	HOXB9	homeobox B9
chr19_+_1753661	4.964	NM_001080488	ONECUT3	one cut homeobox 3
chr11_+_73087670	4.947	NM_032871	RELT	RELT tumor necrosis factor receptor
chr19_+_49375638	4.835	NM_014330	PPP1R15A	protein phosphatase 1, regulatory subunit 15A
chr17_-_13505217	4.825	NM_006042	HS3ST3A1	heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1
chr12_+_13044352	4.718		GPRC5A	G protein-coupled receptor, family C, group 5, member A
chr19_+_45971249	4.718	NM_001114171 NM_006732	FOSB	FBJ murine osteosarcoma viral oncogene homolog B
chr6_+_64282449	4.686		PTP4A1	protein tyrosine phosphatase type IVA, member 1
chr3_+_158288952	4.653	NM_001130156 NM_001130157 NM_001195432 NM_001195433 NM_001195434 NM_022443	MLF1	myeloid leukemia factor 1
chr4_+_30722445	4.634		PCDH7	protocadherin 7
chr12_+_13044493	4.600		GPRC5A	G protein-coupled receptor, family C, group 5, member A
chr1_-_91487543	4.569		ZNF644	zinc finger protein 644
chr1_+_45265896	4.568		PLK3	polo-like kinase 3
chr5_+_52776263	4.546	NM_006350 NM_013409	FST	follistatin
chr1_+_162531349	4.544		UAP1	UDP-N-acteylglucosamine pyrophosphorylase 1
chr6_+_64282429	4.522		PTP4A1	protein tyrosine phosphatase type IVA, member 1
chr13_-_21635629	4.482		LATS2	LATS, large tumor suppressor, homolog 2 (Drosophila)
chr1_+_948846	4.481	NM_005101	ISG15	ISG15 ubiquitin-like modifier
chr6_+_138188352	4.470	NM_006290	TNFAIP3	tumor necrosis factor, alpha-induced protein 3
chr13_-_45563554	4.465	NM_012345	NUFIP1	nuclear fragile X mental retardation protein interacting protein 1
chr12_+_27397214	4.448		STK38L	serine/threonine kinase 38 like
chr16_+_71879858	4.425
chr1_-_91487586	4.357		ZNF644	zinc finger protein 644
chr4_+_84457256	4.347		AGPAT9	1-acylglycerol-3-phosphate O-acyltransferase 9
chr8_+_94929082	4.340	NM_018444 NM_001161780 NM_001161779 NM_001161781	PDP1	pyruvate dehyrogenase phosphatase catalytic subunit 1
chr10_-_99446899	4.333	NM_021732	AVPI1	arginine vasopressin-induced 1
chr5_+_159343739	4.323	NM_000679	ADRA1B	adrenergic, alpha-1B-, receptor
chr1_+_27719151	4.320	NM_005281	GPR3	G protein-coupled receptor 3
chr6_+_30295007	4.320	NM_172016	TRIM39	tripartite motif containing 39
chr12_-_123380682	4.288	NM_024667	VPS37B	vacuolar protein sorting 37 homolog B (S. cerevisiae)
chr3_+_170075449	4.264	NM_001145098 NM_005414	SKIL	SKI-like oncogene
chr13_-_21635703	4.216	NM_014572	LATS2	LATS, large tumor suppressor, homolog 2 (Drosophila)
chr2_-_43453737	4.156	NM_006887	ZFP36L2	zinc finger protein 36, C3H type-like 2
chr17_-_1619473	4.126		MIR22HG	MIR22 host gene (non-protein coding)
chr12_+_27397179	4.104		STK38L	serine/threonine kinase 38 like
chr19_-_44100127	4.101	NM_001007561	IRGQ	immunity-related GTPase family, Q
chr5_+_52776479	4.082		FST	follistatin
chr12_+_27397077	4.038	NM_015000	STK38L	serine/threonine kinase 38 like
chr17_+_39845141	4.009		EIF1	eukaryotic translation initiation factor 1
chr3_+_111578136	4.008		PHLDB2	pleckstrin homology-like domain, family B, member 2
chr7_-_100808832	3.976	NM_003378	VGF	VGF nerve growth factor inducible
chr18_+_57567191	3.972	NM_021127	PMAIP1	phorbol-12-myristate-13-acetate-induced protein 1
chr2_+_169659099	3.942	NM_001039724 NM_001171632 NM_052946	NOSTRIN	nitric oxide synthase trafficker
chr5_-_64777703	3.937	NM_197941	ADAMTS6	ADAM metallopeptidase with thrombospondin type 1 motif, 6
chr10_+_35484829	3.927	NM_182721 NM_182722 NM_182723 NM_182724 NM_182725	CREM	cAMP responsive element modulator
chr2_-_43453724	3.887		ZFP36L2	zinc finger protein 36, C3H type-like 2
chr2_-_192015934	3.820	NM_003151	STAT4	signal transducer and activator of transcription 4
chr6_+_64281910	3.814	NM_003463	PTP4A1	protein tyrosine phosphatase type IVA, member 1
chr1_+_162531229	3.809	NM_003115	UAP1	UDP-N-acteylglucosamine pyrophosphorylase 1
chr7_-_8301767	3.791	NM_001136020	ICA1	islet cell autoantigen 1, 69kDa
chr2_-_43453146	3.767		ZFP36L2	zinc finger protein 36, C3H type-like 2
chr19_+_45504686	3.754	NM_006509	RELB	v-rel reticuloendotheliosis viral oncogene homolog B
chr1_-_91487593	3.746		ZNF644	zinc finger protein 644
chr11_-_67141647	3.736	NM_001166212	CLCF1	cardiotrophin-like cytokine factor 1
chr4_+_84457390	3.662	NM_032717	AGPAT9	1-acylglycerol-3-phosphate O-acyltransferase 9
chr19_+_45349560	3.644		PVRL2	poliovirus receptor-related 2 (herpesvirus entry mediator B)
chr14_-_53417272	3.641		FERMT2	fermitin family member 2
chr17_+_39845126	3.623	NM_005801	EIF1	eukaryotic translation initiation factor 1
chr3_+_8543508	3.619	NM_014583	LMCD1	LIM and cysteine-rich domains 1
chrX_+_30233674	3.603	NM_002364	MAGEB2	melanoma antigen family B, 2
chr9_+_112542496	3.564	NM_053016 NM_007203 NM_147150	PALM2 PALM2-AKAP2	paralemmin 2 PALM2-AKAP2 readthrough
chr3_+_170075494	3.562		SKIL	SKI-like oncogene
chr3_-_150480887	3.539		SIAH2	seven in absentia homolog 2 (Drosophila)
chr7_+_1577118	3.537		MAFK	v-maf musculoaponeurotic fibrosarcoma oncogene homolog K (avian)
chr7_+_22766765	3.526	NM_000600	IL6	interleukin 6 (interferon, beta 2)
chr3_+_170075521	3.484		SKIL	SKI-like oncogene
chr9_-_140353785	3.464	NM_001130969 NM_001130970 NM_001130971 NM_001178064 NM_015537	NELF	nasal embryonic LHRH factor
chr3_-_87040246	3.437	NM_016206	VGLL3	vestigial like 3 (Drosophila)
chr9_-_140353748	3.435		NELF	nasal embryonic LHRH factor
chr5_-_72744351	3.435	NM_004472	FOXD1	forkhead box D1
chr2_-_224467095	3.414		SCG2	secretogranin II
chr3_-_150480917	3.409		SIAH2	seven in absentia homolog 2 (Drosophila)
chr21_-_35899046	3.401	NM_203418	RCAN1	regulator of calcineurin 1
chr7_-_8302141	3.376	NM_004968	ICA1	islet cell autoantigen 1, 69kDa
chr7_+_1580009	3.371		MAFK	v-maf musculoaponeurotic fibrosarcoma oncogene homolog K (avian)
chr16_-_89768094	3.367	NM_152339	SPATA2L	spermatogenesis associated 2-like
chr2_-_157186681	3.363		NR4A2	nuclear receptor subfamily 4, group A, member 2
chr13_-_67804432	3.357	NM_020403 NM_203487	PCDH9	protocadherin 9
chr3_-_87040268	3.347		VGLL3	vestigial like 3 (Drosophila)
chr5_+_72861567	3.328	NM_032175	UTP15	UTP15, U3 small nucleolar ribonucleoprotein, homolog (S. cerevisiae)
chr8_+_90770201	3.327		RIPK2	receptor-interacting serine-threonine kinase 2
chr12_-_132628841	3.310	NM_175066	DDX51	DEAD (Asp-Glu-Ala-Asp) box polypeptide 51
chr2_-_216249682	3.294		FN1	fibronectin 1
chr19_+_45349584	3.252		PVRL2	poliovirus receptor-related 2 (herpesvirus entry mediator B)
chr7_-_41742666	3.244	NM_002192	INHBA	inhibin, beta A
chr7_-_8301681	3.239	NM_022307	ICA1	islet cell autoantigen 1, 69kDa
chr1_+_26496382	3.238	NM_015871	ZNF593	zinc finger protein 593
chr17_-_76836852	3.206	NM_025090	USP36	ubiquitin specific peptidase 36
chr9_+_35538890	3.203		RUSC2	RUN and SH3 domain containing 2
chr16_-_68057098	3.198		DDX28	DEAD (Asp-Glu-Ala-Asp) box polypeptide 28
chr6_+_43138919	3.189	NM_003131	SRF	serum response factor (c-fos serum response element-binding transcription factor)
chr1_-_91487769	3.175	NM_032186 NM_201269	ZNF644	zinc finger protein 644
chr9_-_86153048	3.173	NM_001244959 NM_174938	FRMD3	FERM domain containing 3
chr10_+_6186903	3.164		PFKFB3	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
chr19_+_12902295	3.156	NM_002229	JUNB	jun B proto-oncogene
chr6_-_53213699	3.137		ELOVL5	ELOVL fatty acid elongase 5
chr10_+_6186878	3.116		PFKFB3	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
chr12_+_122150638	3.115	NM_001080825	TMEM120B	transmembrane protein 120B
chr10_+_6244839	3.104	NM_004566	PFKFB3	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
chr6_-_37225360	3.056	NM_145316	TMEM217	transmembrane protein 217
chr1_-_20812727	3.051	NM_018584	CAMK2N1	calcium/calmodulin-dependent protein kinase II inhibitor 1
chr9_-_79520878	3.040	NM_015225	PRUNE2	prune homolog 2 (Drosophila)
chr2_+_231577536	3.038	NM_016289	CAB39	calcium binding protein 39
chrX_-_13835012	3.029		GPM6B	glycoprotein M6B
chr16_-_68057120	2.999		DDX28	DEAD (Asp-Glu-Ala-Asp) box polypeptide 28
chr9_-_140353612	2.997		NELF	nasal embryonic LHRH factor
chr5_-_95297597	2.991	NM_012081	ELL2	elongation factor, RNA polymerase II, 2
chr7_+_38217919	2.981		STARD3NL	STARD3 N-terminal like
chr9_+_35538628	2.968	NM_001135999	RUSC2	RUN and SH3 domain containing 2
chr16_-_75498497	2.932		TMEM170A	transmembrane protein 170A
chr8_+_90769974	2.923	NM_003821	RIPK2	receptor-interacting serine-threonine kinase 2
chrX_+_7065820	2.916		STS	steroid sulfatase (microsomal), isozyme S
chr17_-_7165788	2.905		CLDN7	claudin 7
chr17_-_7166263	2.894	NM_001185023 NM_001307	CLDN7	claudin 7
chr17_-_36831156	2.881	NM_001130677	C17orf96	chromosome 17 open reading frame 96
chr1_+_37940074	2.860	NM_025079	ZC3H12A	zinc finger CCCH-type containing 12A
chr1_-_95392501	2.859	NM_001839	CNN3	calponin 3, acidic
chr9_+_131644427	2.858		LRRC8A	leucine rich repeat containing 8 family, member A
chr8_+_17104384	2.851	NM_001145152 NM_152415	VPS37A	vacuolar protein sorting 37 homolog A (S. cerevisiae)
chr5_-_95297424	2.842		ELL2	elongation factor, RNA polymerase II, 2
chr5_+_138211084	2.838		CTNNA1	catenin (cadherin-associated protein), alpha 1, 102kDa
chr19_-_1863546	2.835	NM_031918	KLF16	Kruppel-like factor 16
chr5_+_52776408	2.825		FST	follistatin
chr6_-_53213586	2.803		ELOVL5	ELOVL fatty acid elongase 5
chr12_+_59989847	2.767		SLC16A7	solute carrier family 16, member 7 (monocarboxylic acid transporter 2)
chr19_-_9731883	2.754	NM_152289	ZNF561	zinc finger protein 561
chr2_-_172967627	2.728		DLX2	distal-less homeobox 2
chr12_+_72148909	2.723		RAB21	RAB21, member RAS oncogene family
chrX_+_102024057	2.721		LOC100287765	uncharacterized LOC100287765
chr16_+_71879893	2.720	NM_001137675	ATXN1L	ataxin 1-like
chr11_+_69455884	2.718		CCND1	cyclin D1
chr6_+_43139190	2.713		SRF	serum response factor (c-fos serum response element-binding transcription factor)
chr12_+_13043955	2.707	NM_003979	GPRC5A	G protein-coupled receptor, family C, group 5, member A
chr19_-_46088084	2.706	NM_001017989 NM_025136	OPA3	optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
chr17_+_685512	2.664	NM_018146	RNMTL1	RNA methyltransferase like 1
chr19_-_9695166	2.657	NM_001008727	ZNF121	zinc finger protein 121
chr17_+_685606	2.654		RNMTL1	RNA methyltransferase like 1

Gene overrepresentation in process category:

Enrichment	P-value	GO Accession	GO Term
1.46	5.42e-06	GO:0044260	cellular macromolecule metabolic process
1.47	3.53e-05	GO:0019222	regulation of metabolic process
1.50	3.65e-05	GO:0031323	regulation of cellular metabolic process
1.33	5.80e-05	GO:0044237	cellular metabolic process
1.70	2.54e-04	GO:0010467	gene expression
1.37	2.82e-04	GO:0043170	macromolecule metabolic process
1.48	2.91e-04	GO:0060255	regulation of macromolecule metabolic process
1.46	3.62e-04	GO:0080090	regulation of primary metabolic process
1.72	3.64e-04	GO:0016070	RNA metabolic process
1.97	3.98e-03	GO:0006351	transcription, DNA-dependent
1.56	4.59e-03	GO:0090304	nucleic acid metabolic process
1.27	4.81e-03	GO:0044238	primary metabolic process
2.45	5.90e-03	GO:0007243	intracellular protein kinase cascade
2.45	5.90e-03	GO:0023014	signal transduction via phosphorylation event
1.24	7.66e-03	GO:0008152	metabolic process
1.84	1.82e-02	GO:0032774	RNA biosynthetic process
6.00	2.65e-02	GO:0001704	formation of primary germ layer
2.59	2.73e-02	GO:0034097	response to cytokine stimulus
1.44	3.35e-02	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.46	3.45e-02	GO:0010468	regulation of gene expression
7.89	3.57e-02	GO:0000188	inactivation of MAPK activity

Gene overrepresentation in compartment category:

Enrichment	P-value	GO Accession	GO Term
1.22	8.10e-11	GO:0044424	intracellular part
1.20	1.66e-09	GO:0005622	intracellular
1.25	6.34e-09	GO:0043229	intracellular organelle
1.25	8.63e-09	GO:0043226	organelle
1.40	1.24e-07	GO:0005634	nucleus
1.26	2.03e-07	GO:0043231	intracellular membrane-bounded organelle
1.26	2.39e-07	GO:0043227	membrane-bounded organelle
1.30	4.45e-04	GO:0044422	organelle part
1.21	7.11e-04	GO:0005737	cytoplasm
1.29	1.15e-03	GO:0044446	intracellular organelle part
2.21	2.42e-03	GO:0005730	nucleolus
1.54	7.51e-03	GO:0031981	nuclear lumen
1.47	9.03e-03	GO:0043233	organelle lumen
1.47	1.05e-02	GO:0070013	intracellular organelle lumen
1.46	1.10e-02	GO:0031974	membrane-enclosed lumen
1.47	1.56e-02	GO:0044428	nuclear part
1.23	1.84e-02	GO:0044444	cytoplasmic part
1.45	4.07e-02	GO:0005829	cytosol

Gene overrepresentation in function category:

Enrichment	P-value	GO Accession	GO Term
1.27	1.86e-05	GO:0005515	protein binding
1.96	1.15e-03	GO:0003723	RNA binding
1.86	1.19e-03	GO:0001071	nucleic acid binding transcription factor activity
1.86	1.19e-03	GO:0003700	sequence-specific DNA binding transcription factor activity
1.13	1.72e-03	GO:0005488	binding
1.40	2.30e-03	GO:0003676	nucleic acid binding
11.28	1.71e-02	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity
10.47	2.58e-02	GO:0033549	MAP kinase phosphatase activity