Motif ID: ATF4.p2

Z-value: 1.234


Transcription factors associated with ATF4.p2:

Gene SymbolEntrez IDGene Name
ATF4 468 activating transcription factor 4 (tax-responsive enhancer element B67)

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
ATF4hg19_v1_chr22_+_39916563_39916625-0.066.0e-01Click!


Activity profile for motif ATF4.p2.

activity profile for motif ATF4.p2


Sorted Z-values histogram for motif ATF4.p2

Sorted Z-values for motif ATF4.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ATF4.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr20_+_33146500 57.822 NM_032514
MAP1LC3A
microtubule-associated protein 1 light chain 3 alpha
chr2_-_216300770 26.284 NM_002026
NM_054034
NM_212474
NM_212476
NM_212478
NM_212482
FN1





fibronectin 1





chr11_-_119187811 20.614 NM_006500
MCAM
melanoma cell adhesion molecule
chr2_-_216300444 11.589 FN1
fibronectin 1
chr2_+_30454396 11.339 NM_030915
LBH
limb bud and heart development homolog (mouse)
chr10_-_50970321 8.646 NM_001143996
NM_001143997
NM_018245
OGDHL


oxoglutarate dehydrogenase-like


chr19_-_9649257 7.966 NM_024106
ZNF426
zinc finger protein 426
chr3_+_8543508 7.452 NM_014583
LMCD1
LIM and cysteine-rich domains 1
chr14_+_68086633 7.415 ARG2
arginase, type II
chr3_+_8543539 7.102 LMCD1
LIM and cysteine-rich domains 1
chr5_-_1112106 6.571 NM_006598
SLC12A7
solute carrier family 12 (potassium/chloride transporters), member 7
chr3_-_99594915 6.521 NM_014890
FILIP1L
filamin A interacting protein 1-like
chr12_+_57998600 6.356 NM_178502
DTX3
deltex homolog 3 (Drosophila)
chr19_-_19932512 6.160 NM_001099269
NM_001145404
ZNF506

zinc finger protein 506

chr16_+_2039945 5.977 NM_004209
SYNGR3
synaptogyrin 3
chr16_+_67694795 5.764 NM_001037281
NM_016948
PARD6A

par-6 partitioning defective 6 homolog alpha (C. elegans)

chr19_-_37407079 5.730 NM_001037232
ZNF829
zinc finger protein 829
chr2_+_219745243 5.546 NM_025216
WNT10A
wingless-type MMTV integration site family, member 10A
chr20_+_58179601 5.477 NM_080672
PHACTR3
phosphatase and actin regulator 3
chr6_+_26204779 5.171 NM_003545
HIST1H4E
histone cluster 1, H4e
chr17_+_4046941 4.967 CYB5D2
cytochrome b5 domain containing 2
chr6_+_139456240 4.888 NM_016217
HECA
headcase homolog (Drosophila)
chr11_+_43963809 4.804 NM_001145033
C11orf96
chromosome 11 open reading frame 96
chr7_+_30174343 4.632 NM_152793
C7orf41
chromosome 7 open reading frame 41
chr19_+_37407230 4.499 NM_001204835
NM_001204836
NM_001204837
NM_001204838
NM_001204839
NM_198539
ZNF568





zinc finger protein 568





chrX_-_106960268 4.417 NM_004089
TSC22D3
TSC22 domain family, member 3
chr19_-_37406918 4.384 NM_001171979
ZNF829
zinc finger protein 829
chr19_-_7553867 4.260 NM_080662
PEX11G
peroxisomal biogenesis factor 11 gamma
chrX_-_106960028 4.168 TSC22D3
TSC22 domain family, member 3
chr4_-_186456580 4.168 NM_001114107
NM_014476
PDLIM3

PDZ and LIM domain 3

chr5_+_121647773 4.154 NM_001242935
NM_005460
SNCAIP

synuclein, alpha interacting protein

chr6_-_10694837 4.131 NM_001145020
C6orf52
chromosome 6 open reading frame 52
chr7_-_129592794 4.106 NM_003344
NM_182697
UBE2H

ubiquitin-conjugating enzyme E2H

chr7_-_129592711 3.898 NM_001202498
UBE2H
ubiquitin-conjugating enzyme E2H
chr2_+_43864433 3.801 NM_172069
PLEKHH2
pleckstrin homology domain containing, family H (with MyTH4 domain) member 2
chr14_+_50999799 3.713 NM_001127713
ATL1
atlastin GTPase 1
chr15_-_48470319 3.593 MYEF2
myelin expression factor 2
chr2_+_220408742 3.576 NM_001005209
TMEM198
transmembrane protein 198
chr14_+_68086655 3.465 ARG2
arginase, type II
chr9_-_99801365 3.465 NM_001333
CTSL2
cathepsin L2
chr11_-_6440631 3.350 NM_145689
APBB1
amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
chr16_-_67700571 3.237 NM_032140
C16orf48
chromosome 16 open reading frame 48
chr1_+_85527992 3.196 NM_145172
WDR63
WD repeat domain 63
chr2_+_71680752 3.187 NM_001130976
NM_001130977
NM_001130978
NM_001130979
NM_001130980
NM_001130981
NM_003494
DYSF






dysferlin, limb girdle muscular dystrophy 2B (autosomal recessive)






chr3_+_10068123 3.174 FANCD2
Fanconi anemia, complementation group D2
chr1_-_20812727 3.052 NM_018584
CAMK2N1
calcium/calmodulin-dependent protein kinase II inhibitor 1
chr15_-_64338519 3.035 NM_014326
DAPK2
death-associated protein kinase 2
chr5_-_16509106 2.974 NM_019000
FAM134B
family with sequence similarity 134, member B
chr17_+_60704747 2.940 NM_006039
MRC2
mannose receptor, C type 2
chr18_+_9708299 2.906 RAB31
RAB31, member RAS oncogene family
chr5_+_139927182 2.855 NM_003732
EIF4EBP3
eukaryotic translation initiation factor 4E binding protein 3
chr2_-_110962577 2.852 NM_000272
NM_001128178
NM_001128179
NM_207181
NPHP1



nephronophthisis 1 (juvenile)



chr21_-_45079327 2.780 NM_007031
HSF2BP
heat shock transcription factor 2 binding protein
chr2_+_68694669 2.769 NM_173545
APLF
aprataxin and PNKP like factor
chr14_+_68086570 2.749 NM_001172
ARG2
arginase, type II
chr12_+_13044352 2.742 GPRC5A
G protein-coupled receptor, family C, group 5, member A
chr12_-_31881949 2.734 AMN1
antagonist of mitotic exit network 1 homolog (S. cerevisiae)
chr14_-_50329567 2.703 RN7SL2
RNA, 7SL, cytoplasmic 2
chr5_-_136834418 2.700 SPOCK1
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
chr20_-_44420538 2.695 NM_080614
WFDC3
WAP four-disulfide core domain 3
chr5_-_16617085 2.681 NM_001034850
FAM134B
family with sequence similarity 134, member B
chr19_-_50979461 2.662 FAM71E1
family with sequence similarity 71, member E1
chr12_+_10365415 2.636 NM_031412
GABARAPL1
GABA(A) receptor-associated protein like 1
chr15_+_75287829 2.629 NM_001178111
NM_001178112
NM_138967
SCAMP5


secretory carrier membrane protein 5


chr10_+_99079017 2.613 NM_005479
FRAT1
frequently rearranged in advanced T-cell lymphomas
chr6_+_86159738 2.586 NT5E
5'-nucleotidase, ecto (CD73)
chr11_-_61584451 2.575 NM_013402
FADS1
fatty acid desaturase 1
chr2_-_27718098 2.575 NM_022823
FNDC4
fibronectin type III domain containing 4
chr2_-_27718059 2.524 FNDC4
fibronectin type III domain containing 4
chr14_+_88851987 2.499 NM_001040428
NM_018418
SPATA7

spermatogenesis associated 7

chr13_-_52378230 2.492 NM_001031719
NM_024705
DHRS12

dehydrogenase/reductase (SDR family) member 12

chr6_-_91006460 2.463 NM_021813
BACH2
BTB and CNC homology 1, basic leucine zipper transcription factor 2
chr2_+_33172368 2.426 NM_206943
LTBP1
latent transforming growth factor beta binding protein 1
chr16_-_4588738 2.388 NM_001199055
NM_001199056
NM_013399
C16orf5


chromosome 16 open reading frame 5


chr1_-_149812733 2.384 NM_021059
NM_001005464
HIST2H3C
HIST2H3A
histone cluster 2, H3c
histone cluster 2, H3a
chr3_+_10068139 2.378 FANCD2
Fanconi anemia, complementation group D2
chr22_+_18121540 2.333 BCL2L13
BCL2-like 13 (apoptosis facilitator)
chr12_+_13044493 2.326 GPRC5A
G protein-coupled receptor, family C, group 5, member A
chr1_+_149824180 2.322 NM_021059
NM_001005464
HIST2H3C
HIST2H3A
histone cluster 2, H3c
histone cluster 2, H3a
chr8_-_11324184 2.294 NM_053279
FAM167A
family with sequence similarity 167, member A
chr1_+_109289294 2.289 STXBP3
syntaxin binding protein 3
chr12_-_31882006 2.280 NM_001113402
AMN1
antagonist of mitotic exit network 1 homolog (S. cerevisiae)
chr7_-_140624280 2.259 NM_004333
BRAF
v-raf murine sarcoma viral oncogene homolog B1
chr1_+_201476283 2.255


chr14_-_103995336 2.218


chr1_-_17445865 2.198 NM_007365
PADI2
peptidyl arginine deiminase, type II
chr2_-_21022812 2.188 NM_021925
C2orf43
chromosome 2 open reading frame 43
chr15_+_80696569 2.183 NM_014862
ARNT2
aryl-hydrocarbon receptor nuclear translocator 2
chr17_-_33288415 2.165 CCT6B
chaperonin containing TCP1, subunit 6B (zeta 2)
chr7_-_8301767 2.155 NM_001136020
ICA1
islet cell autoantigen 1, 69kDa
chr11_+_95523608 2.147 NM_001243776
NM_001243777
NM_014679
CEP57


centrosomal protein 57kDa


chr14_+_88852065 2.125 SPATA7
spermatogenesis associated 7
chr1_-_70671263 2.121 NM_017768
LRRC40
leucine rich repeat containing 40
chr20_+_42839599 2.092 LOC100505783
uncharacterized LOC100505783
chr7_-_8301681 2.084 NM_022307
ICA1
islet cell autoantigen 1, 69kDa
chr3_+_38206968 2.079 NM_005109
OXSR1
oxidative-stress responsive 1
chr11_-_8680382 2.072 NM_014818
TRIM66
tripartite motif containing 66
chr3_+_141087298 2.066 ZBTB38
zinc finger and BTB domain containing 38
chr13_-_33002218 2.051 NM_001079691
NM_052818
N4BP2L1

NEDD4 binding protein 2-like 1

chr7_+_2557496 2.045 NM_002304
LFNG
LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr16_+_29912146 2.030 NM_181718
ASPHD1
aspartate beta-hydroxylase domain containing 1
chr12_+_111471827 2.028 NM_015267
CUX2
cut-like homeobox 2
chrX_+_12993224 2.014 NM_021109
TMSB4X
thymosin beta 4, X-linked
chr5_-_136834231 2.005 SPOCK1
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
chr11_-_18343670 1.988 NM_007216
NM_181507
NM_181508
HPS5


Hermansky-Pudlak syndrome 5


chr3_+_9975513 1.953 NM_015513
NM_001031717
NM_001077415
CRELD1


cysteine-rich with EGF-like domains 1


chr6_+_27100784 1.951 NM_021064
HIST1H2AG
histone cluster 1, H2ag
chr8_+_26240522 1.939 NM_004331
BNIP3L
BCL2/adenovirus E1B 19kDa interacting protein 3-like
chr1_+_52082755 1.939 OSBPL9
oxysterol binding protein-like 9
chr17_+_57642885 1.918 NM_001166301
NM_024612
DHX40

DEAH (Asp-Glu-Ala-His) box polypeptide 40

chr1_+_109289266 1.900 NM_007269
STXBP3
syntaxin binding protein 3
chr6_+_86159301 1.896 NM_001204813
NM_002526
NT5E

5'-nucleotidase, ecto (CD73)

chr14_+_23067128 1.885 NM_022060
ABHD4
abhydrolase domain containing 4
chr8_-_66754276 1.884 PDE7A
phosphodiesterase 7A
chr14_-_50053068 1.877 NM_001030001
NM_001032
RPS29

ribosomal protein S29

chr5_-_72861208 1.866 ANKRA2
ankyrin repeat, family A (RFXANK-like), 2
chr16_-_4588379 1.863 NM_001199054
C16orf5
chromosome 16 open reading frame 5
chr1_+_109289345 1.855 STXBP3
syntaxin binding protein 3
chr5_+_60628085 1.844 NM_020928
ZSWIM6
zinc finger, SWIM-type containing 6
chr6_-_91006580 1.832 NM_001170794
BACH2
BTB and CNC homology 1, basic leucine zipper transcription factor 2
chr22_+_18121446 1.824 NM_015367
BCL2L13
BCL2-like 13 (apoptosis facilitator)
chr6_-_53213699 1.813 ELOVL5
ELOVL fatty acid elongase 5
chr3_+_183165402 1.812 LOC100505687
uncharacterized LOC100505687
chrX_+_43514157 1.811 MAOA
monoamine oxidase A
chr14_+_32030579 1.799 NM_025152
NUBPL
nucleotide binding protein-like
chr19_+_1104614 1.793 NM_001039848
GPX4
glutathione peroxidase 4 (phospholipid hydroperoxidase)
chr17_+_33914320 1.782 AP2B1
adaptor-related protein complex 2, beta 1 subunit
chr8_-_71581419 1.772 NM_016027
LACTB2
lactamase, beta 2
chr13_+_32889594 1.769 NM_000059
BRCA2
breast cancer 2, early onset
chr6_-_116575170 1.763 NM_021648
TSPYL4
TSPY-like 4
chr11_-_6440288 1.756 NM_001164
APBB1
amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
chr2_+_43864405 1.756 PLEKHH2
pleckstrin homology domain containing, family H (with MyTH4 domain) member 2
chr12_+_56552141 1.751 MYL6
myosin, light chain 6, alkali, smooth muscle and non-muscle
chr20_+_19915716 1.736 RIN2
Ras and Rab interactor 2
chr4_+_170541728 1.710 CLCN3
chloride channel 3
chr5_-_121413906 1.706 LOX
lysyl oxidase
chr17_+_60705042 1.704 MRC2
mannose receptor, C type 2
chr16_+_19567021 1.694 C16orf62
chromosome 16 open reading frame 62
chrX_+_102862833 1.686 NM_001006933
NM_032926
TCEAL3

transcription elongation factor A (SII)-like 3

chr5_+_68788387 1.683 NM_001205254
OCLN
occludin
chr15_+_52472257 1.682 LOC100129973
uncharacterized LOC100129973
chr17_+_60705051 1.666 MRC2
mannose receptor, C type 2
chr5_+_112849352 1.658 NM_022828
YTHDC2
YTH domain containing 2
chr4_-_170533762 1.658 NM_001199397
NM_001199398
NM_001199399
NM_001199400
NM_012224
NEK1




NIMA (never in mitosis gene a)-related kinase 1




chr6_+_13925423 1.656 NM_001165033
RNF182
ring finger protein 182
chr8_+_82644663 1.656 NM_152284
CHMP4C
charged multivesicular body protein 4C
chr1_-_70671160 1.653 LRRC40
leucine rich repeat containing 40
chr3_+_186739643 1.652 NM_003032
ST6GAL1
ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
chr7_-_19157262 1.648 NM_000474
TWIST1
twist homolog 1 (Drosophila)
chr1_-_228645517 1.639 NM_033445
HIST3H2A
histone cluster 3, H2a
chr11_-_61584228 1.624 FADS1
fatty acid desaturase 1
chr6_-_121655606 1.623 NM_152730
C6orf170
chromosome 6 open reading frame 170
chr6_-_43477980 1.601 LRRC73
leucine rich repeat containing 73
chr19_+_50979788 1.595 C19orf63
chromosome 19 open reading frame 63
chr12_-_92539614 1.593 NM_001731
BTG1
B-cell translocation gene 1, anti-proliferative
chr8_-_71581354 1.570 LACTB2
lactamase, beta 2
chr1_-_15850692 1.568 CASP9
caspase 9, apoptosis-related cysteine peptidase
chr6_+_89791510 1.554 PNRC1
proline-rich nuclear receptor coactivator 1
chr1_-_115124211 1.553 NM_005872
BCAS2
breast carcinoma amplified sequence 2
chr4_-_170533536 1.549 NEK1
NIMA (never in mitosis gene a)-related kinase 1
chr3_+_10068097 1.546 NM_001018115
NM_033084
FANCD2

Fanconi anemia, complementation group D2

chr1_+_228645807 1.540 NM_175055
HIST3H2BB
histone cluster 3, H2bb
chrX_+_84498993 1.537 NM_021998
ZNF711
zinc finger protein 711
chr2_+_24299751 1.536 LOC375190
UPF0638 protein B
chr18_+_57567191 1.535 NM_021127
PMAIP1
phorbol-12-myristate-13-acetate-induced protein 1
chr12_-_6772252 1.529 NM_001127582
NM_001127583
NM_001127584
NM_001127585
NM_001127586
NM_016162
ING4





inhibitor of growth family, member 4





chr2_+_28615668 1.526 FOSL2
FOS-like antigen 2
chr12_+_72233486 1.525 NM_001146213
NM_001146214
NM_022771
TBC1D15


TBC1 domain family, member 15


chr2_-_110962539 1.515 NPHP1
nephronophthisis 1 (juvenile)
chr14_-_55493770 1.511 WDHD1
WD repeat and HMG-box DNA binding protein 1
chr13_-_101327102 1.508 NM_001079669
NM_032813
TMTC4

transmembrane and tetratricopeptide repeat containing 4

chr14_-_95786095 1.505 NM_024734
CLMN
calmin (calponin-like, transmembrane)
chr19_+_36630999 1.501 CAPNS1
calpain, small subunit 1
chr19_+_36631001 1.488 CAPNS1
calpain, small subunit 1
chr17_-_33288475 1.473 NM_001193529
NM_001193530
NM_006584
CCT6B


chaperonin containing TCP1, subunit 6B (zeta 2)


chr2_+_96068423 1.461 NM_016044
FAHD2A
fumarylacetoacetate hydrolase domain containing 2A
chr7_-_8302141 1.450 NM_004968
ICA1
islet cell autoantigen 1, 69kDa
chr16_-_88772732 1.449 NM_001171815
RNF166
ring finger protein 166
chr21_-_43187265 1.435 RIPK4
receptor-interacting serine-threonine kinase 4
chr21_-_43187197 1.428 NM_020639
RIPK4
receptor-interacting serine-threonine kinase 4
chr12_-_64616032 1.414 NM_152440
C12orf66
chromosome 12 open reading frame 66
chr14_-_55493804 1.395 NM_001008396
NM_007086
WDHD1

WD repeat and HMG-box DNA binding protein 1

chr7_+_20370324 1.384 ITGB8
integrin, beta 8
chr19_-_4517715 1.379 NM_001080400
PLIN4
perilipin 4
chr19_-_50980002 1.364 NM_138411
FAM71E1
family with sequence similarity 71, member E1
chr15_-_48470453 1.363 NM_016132
MYEF2
myelin expression factor 2
chr19_-_36499583 1.331 NM_001039876
C19orf46
chromosome 19 open reading frame 46
chr7_+_107204402 1.327 NM_181581
DUS4L
dihydrouridine synthase 4-like (S. cerevisiae)
chr4_-_84255895 1.326 NM_001199830
HPSE
heparanase
chr22_+_38597938 1.325 NM_001161572
NM_001161574
NM_012323
MAFF


v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian)


chr3_+_50297644 1.325


chr20_+_44637539 1.319 NM_004994
MMP9
matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
chr8_+_94929082 1.315 NM_018444
NM_001161780
NM_001161779
NM_001161781
PDP1



pyruvate dehyrogenase phosphatase catalytic subunit 1



chr17_+_33914278 1.311 NM_001030006
NM_001282
AP2B1

adaptor-related protein complex 2, beta 1 subunit

chr1_-_202896368 1.309 NM_021633
KLHL12
kelch-like 12 (Drosophila)
chr1_+_119683006 1.305


chr12_+_133707212 1.303 NM_015394
ZNF10
zinc finger protein 10
chr5_-_178054072 1.296 CLK4
CDC-like kinase 4
chrX_+_102024057 1.296 LOC100287765
uncharacterized LOC100287765
chr20_+_17949529 1.294 NM_052865
C20orf72
chromosome 20 open reading frame 72

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.