Motif ID: ATF2.p2

Z-value: 0.590


Transcription factors associated with ATF2.p2:

Gene SymbolEntrez IDGene Name
ATF2 1386 activating transcription factor 2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
ATF2hg19_v1_chr2_-_176032850_1760329410.513.2e-06Click!


Activity profile for motif ATF2.p2.

activity profile for motif ATF2.p2


Sorted Z-values histogram for motif ATF2.p2

Sorted Z-values for motif ATF2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ATF2.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr20_+_33146500 7.581 NM_032514
MAP1LC3A
microtubule-associated protein 1 light chain 3 alpha
chr8_+_99076749 4.975 NM_001170806
NM_173549
C8orf47

chromosome 8 open reading frame 47

chr19_+_45971249 4.339 NM_001114171
NM_006732
FOSB

FBJ murine osteosarcoma viral oncogene homolog B

chr11_-_119187811 4.310 NM_006500
MCAM
melanoma cell adhesion molecule
chr10_-_95360959 3.794 NM_006744
RBP4
retinol binding protein 4, plasma
chr9_-_73028278 3.551 KLF9
Kruppel-like factor 9
chr3_-_99594915 3.273 NM_014890
FILIP1L
filamin A interacting protein 1-like
chr1_+_85527992 3.259 NM_145172
WDR63
WD repeat domain 63
chr2_-_216300770 3.091 NM_002026
NM_054034
NM_212474
NM_212476
NM_212478
NM_212482
FN1





fibronectin 1





chr2_+_219745243 2.880 NM_025216
WNT10A
wingless-type MMTV integration site family, member 10A
chr19_-_50979461 2.770 FAM71E1
family with sequence similarity 71, member E1
chr16_+_67694795 2.539 NM_001037281
NM_016948
PARD6A

par-6 partitioning defective 6 homolog alpha (C. elegans)

chr3_-_158390266 2.496 NM_020169
LXN
latexin
chr2_+_37571752 2.472 NM_012413
QPCT
glutaminyl-peptide cyclotransferase
chr16_-_79634610 2.426 NM_001031804
NM_005360
MAF

v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian)

chr11_-_8680382 2.385 NM_014818
TRIM66
tripartite motif containing 66
chr3_-_187463474 2.361 NM_001706
BCL6
B-cell CLL/lymphoma 6
chr6_+_89791510 2.330 PNRC1
proline-rich nuclear receptor coactivator 1
chr1_+_212782103 2.304 ATF3
activating transcription factor 3
chr2_-_216300444 2.289 FN1
fibronectin 1
chr5_-_178054089 2.275 CLK4
CDC-like kinase 4
chr1_-_205391180 2.265 NM_001001552
NM_001199050
NM_001199051
NM_001199052
LEMD1



LEM domain containing 1



chr20_-_39317875 2.244 NM_005461
MAFB
v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian)
chr10_+_95848811 2.203 NM_001165979
PLCE1
phospholipase C, epsilon 1
chr3_-_124774735 2.114 NM_020733
HEG1
HEG homolog 1 (zebrafish)
chr2_-_207082626 2.034 NM_001098199
NM_005279
GPR1

G protein-coupled receptor 1

chr21_-_43187265 2.005 RIPK4
receptor-interacting serine-threonine kinase 4
chr21_-_43187197 2.004 NM_020639
RIPK4
receptor-interacting serine-threonine kinase 4
chr7_-_129592794 1.983 NM_003344
NM_182697
UBE2H

ubiquitin-conjugating enzyme E2H

chr2_+_220408742 1.955 NM_001005209
TMEM198
transmembrane protein 198
chr7_+_30174343 1.899 NM_152793
C7orf41
chromosome 7 open reading frame 41
chr20_-_14318200 1.886 NM_013281
NM_198391
FLRT3

fibronectin leucine rich transmembrane protein 3

chr9_+_126773851 1.839 NM_004789
LHX2
LIM homeobox 2
chr12_-_92539614 1.792 NM_001731
BTG1
B-cell translocation gene 1, anti-proliferative
chr4_-_52883785 1.788 NM_001024611
LRRC66
leucine rich repeat containing 66
chr3_-_187463227 1.786 BCL6
B-cell CLL/lymphoma 6
chrX_+_84498993 1.779 NM_021998
ZNF711
zinc finger protein 711
chr1_+_201476283 1.767


chr7_-_129592711 1.764 NM_001202498
UBE2H
ubiquitin-conjugating enzyme E2H
chr9_-_14086901 1.737 NFIB
nuclear factor I/B
chr16_-_4588738 1.730 NM_001199055
NM_001199056
NM_013399
C16orf5


chromosome 16 open reading frame 5


chr10_-_90967048 1.694 NM_003956
CH25H
cholesterol 25-hydroxylase
chr5_+_140165875 1.691 NM_018900
NM_031410
NM_031411
PCDHA1


protocadherin alpha 1


chr6_+_26204779 1.665 NM_003545
HIST1H4E
histone cluster 1, H4e
chr13_+_97999289 1.664


chrX_+_43514157 1.638 MAOA
monoamine oxidase A
chr19_-_5340700 1.622 NM_002850
NM_130853
NM_130854
NM_130855
PTPRS



protein tyrosine phosphatase, receptor type, S



chr16_-_30103204 1.611 NM_004608
TBX6
T-box 6
chr3_+_69812620 1.597 NM_001184967
MITF
microphthalmia-associated transcription factor
chr3_+_23987514 1.577 NM_001145425
NR1D2
nuclear receptor subfamily 1, group D, member 2
chr5_-_178054072 1.561 CLK4
CDC-like kinase 4
chr3_+_69812961 1.548 NM_006722
MITF
microphthalmia-associated transcription factor
chr13_-_52378230 1.540 NM_001031719
NM_024705
DHRS12

dehydrogenase/reductase (SDR family) member 12

chr15_+_65914269 1.535 NM_004727
SLC24A1
solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
chr11_-_18343670 1.529 NM_007216
NM_181507
NM_181508
HPS5


Hermansky-Pudlak syndrome 5


chr1_+_33546700 1.527 NM_052998
ADC
arginine decarboxylase
chr1_+_209878135 1.517 NM_005525
HSD11B1
hydroxysteroid (11-beta) dehydrogenase 1
chr6_+_136172802 1.513 NM_018945
PDE7B
phosphodiesterase 7B
chr6_+_134758840 1.490 LOC154092
uncharacterized LOC154092
chr20_+_19915716 1.481 RIN2
Ras and Rab interactor 2
chrX_+_102192199 1.479 NM_001031834
RAB40AL
RAB40A, member RAS oncogene family-like
chr3_+_107096187 1.470 NM_032600
CCDC54
coiled-coil domain containing 54
chr20_-_44420538 1.452 NM_080614
WFDC3
WAP four-disulfide core domain 3
chr3_+_101546833 1.443 NM_001005474
NFKBIZ
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta
chr12_+_111471827 1.432 NM_015267
CUX2
cut-like homeobox 2
chr17_+_7462064 1.429 TNFSF13
tumor necrosis factor (ligand) superfamily, member 13
chr2_+_38177595 1.428 NM_001170793
NM_144713
FAM82A1

family with sequence similarity 82, member A1

chr3_-_64211111 1.421 NM_198859
PRICKLE2
prickle homolog 2 (Drosophila)
chr11_-_82782883 1.417 NM_014488
RAB30
RAB30, member RAS oncogene family
chr5_-_95768660 1.392 NM_000439
PCSK1
proprotein convertase subtilisin/kexin type 1
chr17_+_42264300 1.383 NM_001076674
NM_024107
TMUB2

transmembrane and ubiquitin-like domain containing 2

chr8_+_26240522 1.349 NM_004331
BNIP3L
BCL2/adenovirus E1B 19kDa interacting protein 3-like
chr5_+_140254930 1.348 NM_018903
NM_031864
PCDHA12

protocadherin alpha 12

chr12_+_10365415 1.305 NM_031412
GABARAPL1
GABA(A) receptor-associated protein like 1
chr1_+_119683006 1.303


chr14_+_68086633 1.302 ARG2
arginase, type II
chr21_+_47545189 1.301 COL6A2
collagen, type VI, alpha 2
chr6_-_15248886 1.270


chr5_+_73109342 1.267 NM_001244364
RGNEF
190 kDa guanine nucleotide exchange factor
chr12_-_4754275 1.242 NM_006422
AKAP3
A kinase (PRKA) anchor protein 3
chr1_+_183774214 1.224 RGL1
ral guanine nucleotide dissociation stimulator-like 1
chr17_-_41984888 1.222 MPP2
membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
chr3_+_8543508 1.221 NM_014583
LMCD1
LIM and cysteine-rich domains 1
chr3_-_112359962 1.215 NM_199511
NM_199512
CCDC80

coiled-coil domain containing 80

chr8_-_27115897 1.214 NM_030795
STMN4
stathmin-like 4
chr20_+_58179601 1.208 NM_080672
PHACTR3
phosphatase and actin regulator 3
chr11_+_111749947 1.206 NM_022761
C11orf1
chromosome 11 open reading frame 1
chr2_-_157189040 1.197 NM_006186
NR4A2
nuclear receptor subfamily 4, group A, member 2
chr11_-_82782870 1.192 RAB30
RAB30, member RAS oncogene family
chr4_-_170533762 1.185 NM_001199397
NM_001199398
NM_001199399
NM_001199400
NM_012224
NEK1




NIMA (never in mitosis gene a)-related kinase 1




chr17_+_37894558 1.178 NM_001030002
GRB7
growth factor receptor-bound protein 7
chr8_-_21966812 1.175 NM_024815
NUDT18
nudix (nucleoside diphosphate linked moiety X)-type motif 18
chr6_+_31913708 1.175 NM_001710
CFB
complement factor B
chr14_-_50329567 1.160 RN7SL2
RNA, 7SL, cytoplasmic 2
chr3_+_8543539 1.157 LMCD1
LIM and cysteine-rich domains 1
chr5_-_140012730 1.157 CD14
CD14 molecule
chr19_-_17414083 1.152 NM_024527
ABHD8
abhydrolase domain containing 8
chr1_-_173837122 1.151 GAS5
growth arrest-specific 5 (non-protein coding)
chr2_+_54785453 1.142 NM_178313
SPTBN1
spectrin, beta, non-erythrocytic 1
chr19_+_18723666 1.111 NM_012109
TMEM59L
transmembrane protein 59-like
chr17_-_42264023 1.106 C17orf65
chromosome 17 open reading frame 65
chr5_+_159343739 1.101 NM_000679
ADRA1B
adrenergic, alpha-1B-, receptor
chr13_-_48987247 1.100 LPAR6
lysophosphatidic acid receptor 6
chr4_-_170533536 1.098 NEK1
NIMA (never in mitosis gene a)-related kinase 1
chr4_-_186456580 1.077 NM_001114107
NM_014476
PDLIM3

PDZ and LIM domain 3

chr4_-_110354914 1.058 1/2-SBSRNA4
lncRNA_BC009800
chr13_-_48987017 1.055 LPAR6
lysophosphatidic acid receptor 6
chr1_+_212781969 1.052 NM_001040619
NM_001206484
NM_001206488
NM_001674
ATF3



activating transcription factor 3



chr4_-_57253588 1.052 NM_181806
AASDH
aminoadipate-semialdehyde dehydrogenase
chr17_-_42264075 1.040 NM_178542
C17orf65
chromosome 17 open reading frame 65
chr1_-_221915458 1.040 NM_007207
NM_144729
DUSP10

dual specificity phosphatase 10

chr6_+_139456240 1.030 NM_016217
HECA
headcase homolog (Drosophila)
chr5_-_172198160 1.015 NM_004417
DUSP1
dual specificity phosphatase 1
chrX_+_84499037 0.993 ZNF711
zinc finger protein 711
chr6_+_42788793 0.988 NM_015349
KIAA0240
KIAA0240
chr5_+_140588267 0.980 NM_018932
PCDHB12
protocadherin beta 12
chr2_+_132480063 0.973 NM_013310
C2orf27A
chromosome 2 open reading frame 27A
chr3_+_69985750 0.971 NM_000248
NM_001184968
NM_198158
NM_198178
MITF



microphthalmia-associated transcription factor



chr8_-_116681103 0.964 NM_014112
TRPS1
trichorhinophalangeal syndrome I
chr17_-_46655544 0.962 NM_024015
HOXB4
homeobox B4
chr11_+_9596233 0.945 NM_001143976
WEE1
WEE1 homolog (S. pombe)
chr17_+_44590075 0.937 NM_001006607
LRRC37A2
LRRC37A
leucine rich repeat containing 37, member A2
leucine rich repeat containing 37A
chr7_+_89843133 0.937 NM_001040666
STEAP2
STEAP family member 2, metalloreductase
chr21_-_36421558 0.929 RUNX1
runt-related transcription factor 1
chr14_+_93389491 0.928 CHGA
chromogranin A (parathyroid secretory protein 1)
chr15_+_34394273 0.922 NM_152595
PGBD4
piggyBac transposable element derived 4
chr5_-_121413967 0.916 LOX
lysyl oxidase
chr17_+_42264582 0.914 TMUB2
transmembrane and ubiquitin-like domain containing 2
chr20_+_58296264 0.907 NM_183244
NM_183246
PHACTR3

phosphatase and actin regulator 3

chr4_-_70725792 0.906 NM_005420
SULT1E1
sulfotransferase family 1E, estrogen-preferring, member 1
chr4_+_170581212 0.902 NM_001243374
CLCN3
chloride channel 3
chr9_-_73029539 0.900 NM_001206
KLF9
Kruppel-like factor 9
chr19_-_36036390 0.899 LOC100506469
uncharacterized LOC100506469
chr12_+_56224636 0.898 TMEM198B
transmembrane protein 198B, pseudogene
chr6_-_53213699 0.893 ELOVL5
ELOVL fatty acid elongase 5
chr12_-_102455793 0.893 NM_016053
CCDC53
coiled-coil domain containing 53
chr12_-_49999259 0.890 NM_032130
FAM186B
family with sequence similarity 186, member B
chr15_-_34629941 0.890 NM_001042494
NM_001042496
SLC12A6

solute carrier family 12 (potassium/chloride transporters), member 6

chrX_-_47863260 0.885 NM_001007088
NM_006962
NM_001178099
ZNF182


zinc finger protein 182


chr2_-_214015053 0.879 NM_016260
IKZF2
IKAROS family zinc finger 2 (Helios)
chr17_+_42264573 0.877 NM_177441
TMUB2
transmembrane and ubiquitin-like domain containing 2
chr17_-_19651586 0.868 NM_000691
ALDH3A1
aldehyde dehydrogenase 3 family, member A1
chr17_-_47841517 0.856 NM_030802
FAM117A
family with sequence similarity 117, member A
chr1_-_221915393 0.856 DUSP10
dual specificity phosphatase 10
chr5_+_140767402 0.853 NM_003736
NM_032098
PCDHGB4

protocadherin gamma subfamily B, 4

chr2_-_27531113 0.848 NM_003353
UCN
urocortin
chr14_+_24563369 0.846 NM_001018073
NM_004563
PCK2

phosphoenolpyruvate carboxykinase 2 (mitochondrial)

chr5_-_178054001 0.836 NM_020666
CLK4
CDC-like kinase 4
chr2_+_74781846 0.830 DOK1
docking protein 1, 62kDa (downstream of tyrosine kinase 1)
chr5_+_140247767 0.829 NM_018902
NM_031861
PCDHA11

protocadherin alpha 11

chr2_+_207139413 0.826 NM_020923
ZDBF2
zinc finger, DBF-type containing 2
chr5_+_35856990 0.825 NM_002185
IL7R
interleukin 7 receptor
chr4_-_87281177 0.820 MAPK10
mitogen-activated protein kinase 10
chr5_-_140013285 0.810 NM_001040021
NM_001174104
NM_001174105
CD14


CD14 molecule


chr3_-_99833348 0.810 NM_001042459
NM_182909
FILIP1L

filamin A interacting protein 1-like

chr11_+_117049387 0.808 SIDT2
SID1 transmembrane family, member 2
chr6_-_30028755 0.808 ZNRD1-AS1
ZNRD1 antisense RNA 1 (non-protein coding)
chr4_-_153273683 0.804 NM_018315
FBXW7
F-box and WD repeat domain containing 7
chr17_+_37894212 0.802 GRB7
growth factor receptor-bound protein 7
chr1_-_221915426 0.801 DUSP10
dual specificity phosphatase 10
chr9_+_15552871 0.799 NM_173550
C9orf93
chromosome 9 open reading frame 93
chr9_+_97488993 0.797 C9orf3
chromosome 9 open reading frame 3
chr19_+_50979656 0.792 NM_175063
NM_206538
C19orf63

chromosome 19 open reading frame 63

chr5_+_140514787 0.792 NM_015669
PCDHB5
protocadherin beta 5
chr16_-_755718 0.791 NM_153350
FBXL16
F-box and leucine-rich repeat protein 16
chr8_-_66754276 0.790 PDE7A
phosphodiesterase 7A
chr19_+_55795766 0.788 BRSK1
BR serine/threonine kinase 1
chr5_+_71502700 0.786 MAP1B
microtubule-associated protein 1B
chr21_-_44846927 0.784 NM_173354
SIK1
salt-inducible kinase 1
chr9_+_132251403 0.780 LOC100506190
uncharacterized LOC100506190
chr14_+_56584854 0.778 NM_021255
PELI2
pellino homolog 2 (Drosophila)
chr4_+_668250 0.776 MYL5
myosin, light chain 5, regulatory
chr15_-_32162778 0.776 OTUD7A
OTU domain containing 7A
chr12_-_102455763 0.774 CCDC53
coiled-coil domain containing 53
chr17_+_7461591 0.773 NM_001198622
NM_001198623
NM_001198624
NM_003808
NM_172087
NM_172088
TNFSF13





tumor necrosis factor (ligand) superfamily, member 13





chr2_+_97426571 0.769 NM_020184
CNNM4
cyclin M4
chr6_+_39760148 0.769 NM_001201427
DAAM2
dishevelled associated activator of morphogenesis 2
chr6_+_31913763 0.764 CFB
complement factor B
chr2_-_21022812 0.763 NM_021925
C2orf43
chromosome 2 open reading frame 43
chrX_-_15288172 0.763 NM_001031739
NM_001168530
NM_024087
ASB9


ankyrin repeat and SOCS box containing 9


chr7_+_2557496 0.744 NM_002304
LFNG
LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr4_+_144257982 0.742 NM_002039
NM_207123
GAB1

GRB2-associated binding protein 1

chr13_+_32605436 0.741 NM_023037
FRY
furry homolog (Drosophila)
chr19_-_3985460 0.741 NM_001961
EEF2
eukaryotic translation elongation factor 2
chr16_-_54962707 0.738 CRNDE
colorectal neoplasia differentially expressed (non-protein coding)
chr1_-_26233367 0.737 NM_203399
STMN1
stathmin 1
chr19_-_47617008 0.735 NM_015168
ZC3H4
zinc finger CCCH-type containing 4
chr9_+_126774028 0.734 LHX2
LIM homeobox 2
chr5_-_121413906 0.729 LOX
lysyl oxidase
chr14_+_75894508 0.719 NM_001135047
JDP2
Jun dimerization protein 2
chr14_+_32798478 0.716 NM_004274
AKAP6
A kinase (PRKA) anchor protein 6
chr19_-_3985343 0.710 EEF2
eukaryotic translation elongation factor 2
chr6_+_111804533 0.705 TRAF3IP2-AS1
TRAF3IP2 antisense RNA 1 (non-protein coding)
chr3_-_12586962 0.699 NM_001195279
LOC100129480
uncharacterized LOC100129480
chr6_-_53213586 0.697 ELOVL5
ELOVL fatty acid elongase 5
chr1_+_52082755 0.696 OSBPL9
oxysterol binding protein-like 9
chr5_+_118691549 0.694 NM_014350
TNFAIP8
tumor necrosis factor, alpha-induced protein 8
chr5_+_118691692 0.692 TNFAIP8
tumor necrosis factor, alpha-induced protein 8
chr5_-_121414011 0.690 NM_002317
LOX
lysyl oxidase
chr12_+_7282963 0.689 NM_014718
CLSTN3
calsyntenin 3

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.