Motif ID: ARID5B.p2

Z-value: 0.508


Transcription factors associated with ARID5B.p2:

Gene SymbolEntrez IDGene Name
ARID5B 84159 AT rich interactive domain 5B (MRF1-like)

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
ARID5Bhg19_v1_chr10_+_63661395_63661468-0.191.0e-01Click!


Activity profile for motif ARID5B.p2.

activity profile for motif ARID5B.p2


Sorted Z-values histogram for motif ARID5B.p2

Sorted Z-values for motif ARID5B.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ARID5B.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_-_153085963 4.755 NM_001014450
SPRR2A
SPRR2F
small proline-rich protein 2A
small proline-rich protein 2F
chr1_-_153013593 3.279 NM_006945
SPRR2D
small proline-rich protein 2D
chr18_+_61554938 2.658 NM_001143818
NM_002575
SERPINB2

serpin peptidase inhibitor, clade B (ovalbumin), member 2

chr2_-_225811730 2.469 DOCK10
dedicator of cytokinesis 10
chr2_-_216242916 2.243 FN1
fibronectin 1
chr15_+_52201590 2.220 TMOD3
tropomodulin 3 (ubiquitous)
chr7_+_116660291 2.215 ST7
suppression of tumorigenicity 7
chr2_-_216246961 2.190 FN1
fibronectin 1
chr18_-_29993195 2.115


chr12_-_91576579 2.054 DCN
decorin
chr1_-_114414245 1.739 NM_001193431
NM_012411
NM_015967
PTPN22


protein tyrosine phosphatase, non-receptor type 22 (lymphoid)


chr2_-_216289936 1.733 FN1
fibronectin 1
chr7_-_41742666 1.658 NM_002192
INHBA
inhibin, beta A
chr16_+_82068958 1.554 HSD17B2
hydroxysteroid (17-beta) dehydrogenase 2
chr16_+_82068910 1.532 HSD17B2
hydroxysteroid (17-beta) dehydrogenase 2
chr17_+_3379295 1.520 NM_000049
ASPA
aspartoacylase
chr10_+_102123420 1.416


chr2_-_216241321 1.398 FN1
fibronectin 1
chr3_-_74570262 1.384 NM_020872
CNTN3
contactin 3 (plasmacytoma associated)
chr12_-_15038724 1.369 NM_000900
NM_001190839
MGP

matrix Gla protein

chr12_-_91576805 1.345 NM_001920
DCN
decorin
chr1_-_168106810 1.304 GPR161
G protein-coupled receptor 161
chr1_-_168106727 1.278 GPR161
G protein-coupled receptor 161
chr15_+_25068793 1.215 NM_022806
NM_022807
NM_022808
SNRPN


small nuclear ribonucleoprotein polypeptide N


chr5_+_148731226 1.191 GRPEL2
GrpE-like 2, mitochondrial (E. coli)
chr17_-_76732944 1.188


chr1_-_51887740 1.135 NM_001159969
EPS15
epidermal growth factor receptor pathway substrate 15
chr2_+_102508377 1.093 MAP4K4
mitogen-activated protein kinase kinase kinase kinase 4
chr1_-_153044083 1.045 NM_001017418
SPRR2B
small proline-rich protein 2B
chr5_+_140560979 1.036 NM_020957
PCDHB16
protocadherin beta 16
chr2_+_102508333 1.021 MAP4K4
mitogen-activated protein kinase kinase kinase kinase 4
chr12_-_10588543 1.014 NM_002260
KLRC2
KLRC3
killer cell lectin-like receptor subfamily C, member 2
killer cell lectin-like receptor subfamily C, member 3
chr6_+_80340971 0.998 NM_031469
SH3BGRL2
SH3 domain binding glutamic acid-rich protein like 2
chr7_-_24797557 0.953 NM_001127454
NM_004403
DFNA5

deafness, autosomal dominant 5

chr7_+_143079925 0.938 ZYX
zyxin
chr3_-_197300193 0.927 NM_203315
BDH1
3-hydroxybutyrate dehydrogenase, type 1
chr17_+_61086897 0.926 NM_025185
TANC2
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
chr3_+_159557649 0.875 NM_001197109
SCHIP1
schwannomin interacting protein 1
chr4_+_77610610 0.845 SHROOM3
shroom family member 3
chr1_-_168106535 0.819 GPR161
G protein-coupled receptor 161
chrX_-_15683153 0.771 NM_020665
TMEM27
transmembrane protein 27
chr2_-_55199894 0.762


chr3_+_159557745 0.747 SCHIP1
schwannomin interacting protein 1
chr9_-_85946875 0.742 NM_001244961
FRMD3
FERM domain containing 3
chr12_+_65224214 0.734


chr9_+_33750463 0.726 NM_001197097
NM_007343
NM_001197098
PRSS3


protease, serine, 3


chr19_-_36499583 0.723 NM_001039876
C19orf46
chromosome 19 open reading frame 46
chr1_-_205391180 0.711 NM_001001552
NM_001199050
NM_001199051
NM_001199052
LEMD1



LEM domain containing 1



chr10_+_95848811 0.705 NM_001165979
PLCE1
phospholipase C, epsilon 1
chr1_-_247054277 0.682 AHCTF1
AT hook containing transcription factor 1
chr8_+_92114846 0.675 NM_001129890
LRRC69
leucine rich repeat containing 69
chr1_+_210001399 0.674 DIEXF
digestive organ expansion factor homolog (zebrafish)
chr2_+_183582667 0.671 DNAJC10
DnaJ (Hsp40) homolog, subfamily C, member 10
chr2_+_183608329 0.669 DNAJC10
DnaJ (Hsp40) homolog, subfamily C, member 10
chr15_-_80263460 0.654 NM_001114735
NM_004049
BCL2A1

BCL2-related protein A1

chr21_+_39628663 0.653 NM_002243
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr19_-_20748540 0.643 NM_001159293
ZNF737
zinc finger protein 737
chr4_+_169013687 0.629 NM_007193
ANXA10
annexin A10
chr12_-_50616425 0.615 NM_001113547
LIMA1
LIM domain and actin binding 1
chr4_+_54292035 0.597 FIP1L1
FIP1 like 1 (S. cerevisiae)
chr15_-_55562483 0.596 NM_183234
NM_004580
RAB27A

RAB27A, member RAS oncogene family

chr5_+_52856460 0.593 NM_002495
NDUFS4
NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase)
chr3_-_57312979 0.584 NM_130387
ASB14
ankyrin repeat and SOCS box containing 14
chr1_-_59147727 0.583


chrX_+_135278912 0.583 NM_001159701
NM_001159699
FHL1

four and a half LIM domains 1

chr3_+_190105660 0.576 NM_006580
CLDN16
claudin 16
chr14_-_24711767 0.573 NM_001099274
NM_012461
TINF2

TERF1 (TRF1)-interacting nuclear factor 2

chr16_-_3843474 0.554 CREBBP
CREB binding protein
chr7_+_77469446 0.549 NM_001127357
NM_001127359
NM_020432
PHTF2


putative homeodomain transcription factor 2


chr2_-_31030271 0.549 NM_144575
CAPN13
calpain 13
chr20_+_123230 0.538 NM_030931
DEFB126
defensin, beta 126
chr1_-_161337663 0.536 NM_001013625
C1orf192
chromosome 1 open reading frame 192
chr10_+_118187381 0.533 NM_001011709
PNLIPRP3
pancreatic lipase-related protein 3
chr1_+_78245306 0.533 NM_198549
FAM73A
family with sequence similarity 73, member A
chr7_+_28338939 0.527 NM_182899
CREB5
cAMP responsive element binding protein 5
chr19_-_52255099 0.520 NM_001193306
NM_002029
FPR1

formyl peptide receptor 1

chr19_-_43031343 0.519 CEACAM1
carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
chr5_+_52856472 0.517 NDUFS4
NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase)
chr1_+_145524989 0.510 NM_003637
ITGA10
integrin, alpha 10
chr10_-_29923900 0.509 NM_021738
SVIL
supervillin
chr7_-_104909442 0.502 NM_182691
SRPK2
SRSF protein kinase 2
chr6_+_42896859 0.501 NM_006586
CNPY3
canopy 3 homolog (zebrafish)
chr11_+_101983170 0.497 NM_001195045
YAP1
Yes-associated protein 1
chr15_+_71433787 0.497 NM_024817
THSD4
thrombospondin, type I, domain containing 4
chr14_+_62164339 0.487 NM_001243084
HIF1A
hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
chr8_-_11710921 0.481


chr3_+_102153858 0.478 NM_175056
ZPLD1
zona pellucida-like domain containing 1
chr6_-_56716713 0.465 DST
dystonin
chr5_+_65372744 0.457 ERBB2IP
erbb2 interacting protein
chrX_-_70331297 0.457 NM_000206
IL2RG
interleukin 2 receptor, gamma
chr2_-_165424993 0.454 GRB14
growth factor receptor-bound protein 14
chr1_+_84647342 0.451 NM_001242862
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr5_-_98262217 0.451 NM_001270
CHD1
chromodomain helicase DNA binding protein 1
chr5_+_137673223 0.449 NM_001135647
FAM53C
family with sequence similarity 53, member C
chr17_+_48348766 0.449 NM_001168215
TMEM92
transmembrane protein 92
chr1_-_205601999 0.440 NM_001973
NM_021795
ELK4

ELK4, ETS-domain protein (SRF accessory protein 1)

chr4_+_95376396 0.439 PDLIM5
PDZ and LIM domain 5
chr2_-_74382352 0.438


chr13_-_114538953 0.438 NM_001143945
GAS6
growth arrest-specific 6
chr1_-_29309092 0.435


chr13_+_53216564 0.433 HNRNPA1L2
heterogeneous nuclear ribonucleoprotein A1-like 2
chr1_+_210001351 0.429 DIEXF
digestive organ expansion factor homolog (zebrafish)
chr7_+_116660263 0.424 ST7
suppression of tumorigenicity 7
chr6_-_11382501 0.417 NM_001142393
NEDD9
neural precursor cell expressed, developmentally down-regulated 9
chr15_+_80733579 0.412 ARNT2
aryl-hydrocarbon receptor nuclear translocator 2
chr15_+_80364902 0.412 NM_001242915
NM_001242916
ZFAND6

zinc finger, AN1-type domain 6

chrX_+_149613719 0.410 NM_001177466
NM_005491
MAMLD1

mastermind-like domain containing 1

chr15_-_80207597 0.409 NM_001100879
ST20
suppressor of tumorigenicity 20
chr14_+_64680858 0.407 NM_182913
SYNE2
spectrin repeat containing, nuclear envelope 2
chr5_+_92918924 0.406 NM_005654
NR2F1
nuclear receptor subfamily 2, group F, member 1
chr10_+_15085894 0.405 NM_001039702
NM_018324
OLAH

oleoyl-ACP hydrolase

chr1_-_9117554 0.403 SLC2A5
solute carrier family 2 (facilitated glucose/fructose transporter), member 5
chr4_-_151773972 0.394


chr9_-_123812535 0.391 NM_001735
C5
complement component 5
chr6_-_86351156 0.391 NM_001159675
NM_001159676
SYNCRIP

synaptotagmin binding, cytoplasmic RNA interacting protein

chr5_-_94224601 0.390 MCTP1
multiple C2 domains, transmembrane 1
chr2_+_128928040 0.384 UGGT1
UDP-glucose glycoprotein glucosyltransferase 1
chr3_+_156394452 0.383 NM_001184718
TIPARP
TCDD-inducible poly(ADP-ribose) polymerase
chr12_+_101988746 0.382 NM_002465
NM_206819
NM_206820
NM_206821
MYBPC1



myosin binding protein C, slow type



chr6_-_112041253 0.378 NM_153047
FYN
FYN oncogene related to SRC, FGR, YES
chr1_+_210001267 0.372 NM_014388
DIEXF
digestive organ expansion factor homolog (zebrafish)
chr6_+_30130982 0.370 NM_033229
TRIM15
tripartite motif containing 15
chr18_+_72166822 0.369 NM_001168499
CNDP2
CNDP dipeptidase 2 (metallopeptidase M20 family)
chr10_+_69869249 0.366 NM_032578
MYPN
myopalladin
chr1_-_104238785 0.361 NM_004038
NM_001008218
NM_001008219
AMY1A
AMY1B
AMY1C
amylase, alpha 1A (salivary)
amylase, alpha 1B (salivary)
amylase, alpha 1C (salivary)
chr10_+_124145584 0.361 NM_001195608
PLEKHA1
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
chr17_-_1248346 0.359 PAFAH1B1
platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
chr1_+_171481164 0.357 PRRC2C
proline-rich coiled-coil 2C
chr19_+_41099071 0.355 NM_003573
LTBP4
latent transforming growth factor beta binding protein 4
chrX_-_101410761 0.352 NM_001159560
NM_001012978
BEX5

brain expressed, X-linked 5

chr2_+_68961912 0.350 NM_001007231
NM_001166277
ARHGAP25

Rho GTPase activating protein 25

chr2_+_170662044 0.347 SSB
Sjogren syndrome antigen B (autoantigen La)
chr2_+_119699744 0.342 NM_006770
MARCO
macrophage receptor with collagenous structure
chr1_+_104198301 0.340 NM_004038
NM_001008218
NM_001008219
AMY1A
AMY1B
AMY1C
amylase, alpha 1A (salivary)
amylase, alpha 1B (salivary)
amylase, alpha 1C (salivary)
chr12_-_28124915 0.339 NM_002820
NM_198965
PTHLH

parathyroid hormone-like hormone

chr14_+_67831484 0.333 EIF2S1
eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
chr3_-_129599220 0.330 NM_001017395
TMCC1
transmembrane and coiled-coil domain family 1
chr8_+_55528626 0.329 NM_006269
RP1
retinitis pigmentosa 1 (autosomal dominant)
chr5_+_150157507 0.329 NM_032947
C5orf62
chromosome 5 open reading frame 62
chr22_-_43042976 0.328 NM_001129819
NM_001171661
NM_007326
CYB5R3


cytochrome b5 reductase 3


chr1_+_178310605 0.328 NM_004841
RASAL2
RAS protein activator like 2
chr1_+_104292439 0.325 NM_004038
NM_001008218
NM_001008219
AMY1A
AMY1B
AMY1C
amylase, alpha 1A (salivary)
amylase, alpha 1B (salivary)
amylase, alpha 1C (salivary)
chrX_+_18460343 0.324 NM_001037343
CDKL5
cyclin-dependent kinase-like 5
chr18_-_46469118 0.321 NM_001190823
SMAD7
SMAD family member 7
chr21_+_30517897 0.321 C21orf7
chromosome 21 open reading frame 7
chr12_+_29376596 0.320 NM_018099
FAR2
fatty acyl CoA reductase 2
chr10_-_98290309 0.310 TM9SF3
transmembrane 9 superfamily member 3
chr6_-_32160637 0.310 GPSM3
G-protein signaling modulator 3
chr1_+_44435649 0.309 NM_001039589
NM_001384
DPH2

DPH2 homolog (S. cerevisiae)

chr1_+_20964414 0.309


chr12_-_50595303 0.308 NM_001243775
LIMA1
LIM domain and actin binding 1
chr17_+_75181294 0.304 NM_001144001
SEC14L1
SEC14-like 1 (S. cerevisiae)
chr4_+_74606222 0.301 NM_000584
IL8
interleukin 8
chr11_+_129979330 0.293 APLP2
amyloid beta (A4) precursor-like protein 2
chr18_+_72166568 0.292 CNDP2
CNDP dipeptidase 2 (metallopeptidase M20 family)
chr13_-_110802708 0.291 COL4A1
collagen, type IV, alpha 1
chr14_+_74035762 0.291 NM_006821
ACOT2
acyl-CoA thioesterase 2
chr2_+_27851514 0.289 NM_001145047
NM_001145048
NM_001145049
GPN1


GPN-loop GTPase 1


chrX_+_54834107 0.289 NM_177433
MAGED2
melanoma antigen family D, 2
chr3_-_158390266 0.288 NM_020169
LXN
latexin
chr14_-_64006402 0.285 PPP2R5E
protein phosphatase 2, regulatory subunit B', epsilon isoform
chr11_-_121986800 0.285 NM_001001786
BLID
BH3-like motif containing, cell death inducer
chr1_+_116925991 0.283 NM_001160234
ATP1A1
ATPase, Na+/K+ transporting, alpha 1 polypeptide
chr6_-_136788012 0.283 NM_001198615
MAP7
microtubule-associated protein 7
chr14_+_35514112 0.279 NM_001079519
FAM177A1
family with sequence similarity 177, member A1
chr6_+_42897184 0.277 CNPY3
canopy 3 homolog (zebrafish)
chr6_+_64286348 0.270 PTP4A1
protein tyrosine phosphatase type IVA, member 1
chr12_+_52347163 0.268 NM_020327
ACVR1B
activin A receptor, type IB
chr1_-_209825797 0.267 NM_000228
LAMB3
laminin, beta 3
chr1_+_211519705 0.266 NM_145759
TRAF5
TNF receptor-associated factor 5
chr19_-_3969734 0.265 NM_001348
DAPK3
death-associated protein kinase 3
chr4_+_41700736 0.265 LIMCH1
LIM and calponin homology domains 1
chr1_+_210501595 0.265 NM_001122834
NM_001170564
HHAT

hedgehog acyltransferase

chr6_+_7402879 0.264 NM_153005
RIOK1
RIO kinase 1 (yeast)
chr12_+_54410893 0.263 HOXC5
HOXC6
homeobox C5
homeobox C6
chr12_-_121736110 0.262 NM_006549
NM_153499
NM_153500
NM_172214
NM_172215
NM_172216
CAMKK2





calcium/calmodulin-dependent protein kinase kinase 2, beta





chr4_+_77356252 0.259 NM_020859
SHROOM3
shroom family member 3
chr12_-_102512277 0.259 NM_024057
NUP37
nucleoporin 37kDa
chr10_-_105845556 0.258 COL17A1
collagen, type XVII, alpha 1
chr17_-_8424217 0.256 MYH10
myosin, heavy chain 10, non-muscle
chr3_-_126327397 0.256 NM_001039783
TXNRD3NB
thioredoxin reductase 3 neighbor
chr10_-_93669184 0.255 NM_152429
FGFBP3
fibroblast growth factor binding protein 3
chr3_-_49399969 0.255 RHOA
ras homolog gene family, member A
chr19_+_20188800 0.255 NM_007138
ZNF90
zinc finger protein 90
chr3_+_44692500 0.254 ZNF35
zinc finger protein 35
chr3_+_196594757 0.248 SENP5
SUMO1/sentrin specific peptidase 5
chr1_-_197552304 0.247 DENND1B
DENN/MADD domain containing 1B
chr6_-_47253962 0.246 TNFRSF21
tumor necrosis factor receptor superfamily, member 21
chr3_-_52713728 0.242 NM_018165
NM_181042
PBRM1

polybromo 1

chr5_+_140180782 0.241 NM_018906
NM_031497
PCDHA3

protocadherin alpha 3

chr12_+_56324945 0.239 NM_001345
DGKA
diacylglycerol kinase, alpha 80kDa
chr16_+_19727698 0.239 NM_153208
IQCK
IQ motif containing K
chr9_+_706744 0.238 NM_153186
KANK1
KN motif and ankyrin repeat domains 1
chr6_-_47254143 0.236 TNFRSF21
tumor necrosis factor receptor superfamily, member 21
chr2_-_37544165 0.234 NM_005813
PRKD3
protein kinase D3
chr6_-_2840683 0.233 SERPINB1
serpin peptidase inhibitor, clade B (ovalbumin), member 1
chr10_-_113933517 0.233 GPAM
glycerol-3-phosphate acyltransferase, mitochondrial
chrX_-_76814217 0.233 ATRX
alpha thalassemia/mental retardation syndrome X-linked
chr1_+_36636690 0.231 MAP7D1
MAP7 domain containing 1
chr1_+_210001363 0.229 DIEXF
digestive organ expansion factor homolog (zebrafish)

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
67.05 3.66e-05 GO:0031424 keratinization
44.02 2.04e-04 GO:0030216 keratinocyte differentiation
38.08 3.66e-04 GO:0009913 epidermal cell differentiation
18.56 6.36e-04 GO:0008544 epidermis development
6.38 7.18e-03 GO:0009888 tissue development
16.12 1.09e-02 GO:0030855 epithelial cell differentiation

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
134.07 5.70e-07 GO:0001533 cornified envelope

Nothing significant found in function category.