Motif ID: AR.p2

Z-value: 0.543


Transcription factors associated with AR.p2:

Gene SymbolEntrez IDGene Name
AR 367 androgen receptor

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
ARhg19_v1_chrX_+_66788682_667886820.831.8e-20Click!


Activity profile for motif AR.p2.

activity profile for motif AR.p2


Sorted Z-values histogram for motif AR.p2

Sorted Z-values for motif AR.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of AR.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr14_-_107211131 2.613 IGHG1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr14_-_107199126 2.484 IGHG3
immunoglobulin heavy constant gamma 3 (G3m marker)
chr7_+_150147882 2.220 GIMAP8
GTPase, IMAP family member 8
chr14_-_106691698 2.096


chr7_+_150147936 1.898 NM_175571
GIMAP8
GTPase, IMAP family member 8
chr1_-_1149495 1.890 NM_003327
TNFRSF4
tumor necrosis factor receptor superfamily, member 4
chr12_+_113416267 1.782 NM_001032731
NM_002535
NM_016817
OAS2


2'-5'-oligoadenylate synthetase 2, 69/71kDa


chr18_-_48346297 1.671 NM_001127175
NM_001127176
NM_031939
MRO


maestro


chr16_+_89679956 1.664 DPEP1
dipeptidase 1 (renal)
chr14_-_106586333 1.646 IGHV4-31
immunoglobulin heavy variable 4-31
chr14_-_106692107 1.624 IGHV4-31
IGHA1
IGHD
IGHG1
IGHG3
immunoglobulin heavy variable 4-31
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant delta
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 3 (G3m marker)
chr14_-_106518424 1.595 IGH@
IGHA1
IGHG1
IGHG2
IGHM
immunoglobulin heavy locus
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 2 (G2m marker)
immunoglobulin heavy constant mu
chr14_-_107113943 1.580 IGHA1
IGHG1
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr14_-_106573348 1.571 IGHV4-31
IGHA1
IGHA2
IGHG1
IGHG3
IGHM
immunoglobulin heavy variable 4-31
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant alpha 2 (A2m marker)
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 3 (G3m marker)
immunoglobulin heavy constant mu
chr5_+_140625146 1.568 NM_018935
PCDHB15
protocadherin beta 15
chr14_-_106926393 1.535 IGHA1
IGHG1
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr14_-_106994001 1.523 IGHV3-48
IGH@
IGHA1
IGHM
immunoglobulin heavy variable 3-48
immunoglobulin heavy locus
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant mu
chr2_-_109605616 1.492 EDAR
ectodysplasin A receptor
chr8_+_11839829 1.486 NM_001033017
DEFB135
defensin, beta 135
chr9_-_75568232 1.483 NM_000689
ALDH1A1
aldehyde dehydrogenase 1 family, member A1
chr14_-_107131217 1.463 IGHA1
immunoglobulin heavy constant alpha 1
chr14_-_65346554 1.458 SPTB
spectrin, beta, erythrocytic
chr14_-_106725620 1.322 IGHV4-31
IGHV3-23
IGHA1
IGHG1
IGHM
immunoglobulin heavy variable 4-31
immunoglobulin heavy variable 3-23
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant mu
chr14_-_106552313 1.301 IGHA1
IGHD
IGHG1
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant delta
immunoglobulin heavy constant gamma 1 (G1m marker)
chr14_-_107048697 1.227 IGHG1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr3_-_58563490 1.045 NM_001076778
NM_007177
FAM107A

family with sequence similarity 107, member A

chrX_-_6453158 1.007 NM_016379
VCX2
VCX3A
variable charge, X-linked 2
variable charge, X-linked 3A
chr14_-_107099379 1.001 IGHG1
IGHG3
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 3 (G3m marker)
chr4_-_42154576 0.990 BEND4
BEN domain containing 4
chr9_-_107361693 0.990 NM_001004482
OR13C5
olfactory receptor, family 13, subfamily C, member 5
chr8_+_100025534 0.950 VPS13B
vacuolar protein sorting 13 homolog B (yeast)
chr2_-_56412904 0.910 LOC100129434
uncharacterized LOC100129434
chr14_-_21493858 0.910 NDRG2
NDRG family member 2
chr8_+_7580612 0.882 NM_001164451
NM_001164449
FAM90A18
FAM90A19
family with sequence similarity 90, member A18
family with sequence similarity 90, member A19
chr8_+_7611203 0.882 NM_001164451
NM_001164449
FAM90A18
FAM90A19
family with sequence similarity 90, member A18
family with sequence similarity 90, member A19
chr8_+_7595908 0.838 NM_001164450
FAM90A8
family with sequence similarity 90, member A8
chr8_+_7618851 0.817 NM_001164448
FAM90A9
family with sequence similarity 90, member A9
chr8_+_7626498 0.813 NM_001164447
FAM90A10
family with sequence similarity 90, member A10
chr8_+_7572964 0.782 NM_001164456
NM_001164452
FAM90A13
FAM90A14
family with sequence similarity 90, member A13
family with sequence similarity 90, member A14
chr1_+_12185955 0.767 NM_152942
TNFRSF8
tumor necrosis factor receptor superfamily, member 8
chr6_-_26235160 0.766 NM_005320
HIST1H1D
histone cluster 1, H1d
chrX_+_8432870 0.766 NM_001001888
VCX3B
VCX3A
variable charge, X-linked 3B
variable charge, X-linked 3A
chr14_-_106725232 0.753 ZCWPW2
IGHV3-23
IGKV3-20
IGK@
zinc finger, CW type with PWWP domain 2
immunoglobulin heavy variable 3-23
immunoglobulin kappa variable 3-20
immunoglobulin kappa locus
chr8_+_7152535 0.745 NM_001164453
FAM90A20
family with sequence similarity 90, member A20
chr19_+_35630391 0.739 NM_005031
FXYD1
FXYD domain containing ion transport regulator 1
chr12_+_10163225 0.721 NM_001129998
NM_205852
CLEC12B

C-type lectin domain family 12, member B

chr9_+_127213422 0.719 NM_001161808
GPR144
G protein-coupled receptor 144
chr8_-_7417233 0.697 NM_001136572
FAM90A7
family with sequence similarity 90, member A7
chr7_-_131833385 0.667 PLXNA4
plexin A4
chr16_-_20338808 0.666 NM_001007240
NM_001007241
NM_001007242
NM_001502
GP2



glycoprotein 2 (zymogen granule membrane)



chr8_-_7440174 0.666 NM_001136572
FAM90A7
family with sequence similarity 90, member A7
chr1_-_202129705 0.659 PTPN7
protein tyrosine phosphatase, non-receptor type 7
chr11_+_74862031 0.643 NM_001145212
NM_007256
SLCO2B1

solute carrier organic anion transporter family, member 2B1

chr3_-_120401401 0.632 NM_000187
HGD
homogentisate 1,2-dioxygenase
chr11_-_7847518 0.612 NM_153445
OR5P3
olfactory receptor, family 5, subfamily P, member 3
chr21_-_35884503 0.601 KCNE1
potassium voltage-gated channel, Isk-related family, member 1
chr11_+_55606226 0.574 NM_001005496
OR5D16
olfactory receptor, family 5, subfamily D, member 16
chr11_-_64528186 0.574 NM_001164716
NM_005609
PYGM

phosphorylase, glycogen, muscle

chr19_-_54876671 0.565 NM_002287
NM_021706
LAIR1

leukocyte-associated immunoglobulin-like receptor 1

chr1_+_153388999 0.547 NM_176823
S100A7A
S100 calcium binding protein A7A
chr20_-_30433320 0.544 NM_004118
FOXS1
forkhead box S1
chr1_-_202129731 0.513 PTPN7
protein tyrosine phosphatase, non-receptor type 7
chr2_-_109605668 0.488 NM_022336
EDAR
ectodysplasin A receptor
chr19_+_17638064 0.486 FAM129C
family with sequence similarity 129, member C
chr14_-_106791054 0.452 IGHV4-31
IGHV3-30
IGHA1
IGHD
IGHG1
IGHG2
IGHG3
IGHM
SCFV
immunoglobulin heavy variable 4-31
immunoglobulin heavy variable 3-30
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant delta
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 2 (G2m marker)
immunoglobulin heavy constant gamma 3 (G3m marker)
immunoglobulin heavy constant mu
single-chain Fv fragment
chrX_+_150345055 0.431 NM_004224
GPR50
G protein-coupled receptor 50
chr9_-_77502635 0.415 NM_001177310
TRPM6
transient receptor potential cation channel, subfamily M, member 6
chr7_+_87563432 0.401 NM_004194
NM_016351
NM_021721
NM_021722
NM_021723
ADAM22




ADAM metallopeptidase domain 22




chr19_-_41934634 0.388 NM_198540
B3GNT8
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8
chr6_-_6320897 0.381 NM_000129
F13A1
coagulation factor XIII, A1 polypeptide
chr19_+_55417507 0.375 NM_001145457
NM_001145458
NM_001242356
NM_001242357
NM_004829
NCR1




natural cytotoxicity triggering receptor 1




chr9_+_135037015 0.370 NTNG2
netrin G2
chr1_-_27953046 0.368 NM_001042729
FGR
Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog
chr1_-_150738255 0.366 CTSS
cathepsin S
chr14_-_21493910 0.351 NM_016250
NM_201535
NM_201536
NM_201537
NDRG2



NDRG family member 2



chr15_-_40398286 0.340 NM_001003942
NM_001003943
BMF

Bcl2 modifying factor

chr3_-_152058778 0.336 NM_001123228
TMEM14E
transmembrane protein 14E
chr6_-_6320875 0.333 F13A1
coagulation factor XIII, A1 polypeptide
chr13_+_113777112 0.328 NM_000504
F10
coagulation factor X
chr4_-_10686314 0.317 NM_052964
CLNK
cytokine-dependent hematopoietic cell linker
chr11_-_113577023 0.316 NM_030770
TMPRSS5
transmembrane protease, serine 5
chr19_+_50472856 0.308 SIGLEC16
sialic acid binding Ig-like lectin 16 (gene/pseudogene)
chr1_-_173174611 0.307 TNFSF4
tumor necrosis factor (ligand) superfamily, member 4
chr4_-_155312448 0.298 NM_017639
DCHS2
dachsous 2 (Drosophila)
chr2_+_241544819 0.296 NM_001195381
NM_001195382
GPR35

G protein-coupled receptor 35

chr17_+_37824506 0.291 NM_002686
PNMT
phenylethanolamine N-methyltransferase
chr14_+_21467413 0.288 NM_014579
SLC39A2
solute carrier family 39 (zinc transporter), member 2
chr1_-_150738232 0.285 CTSS
cathepsin S
chr8_+_7144913 0.283 NM_001164455
FAM90A5
family with sequence similarity 90, member A5
chr8_+_7137291 0.266 NM_001164456
NM_001164452
FAM90A13
FAM90A14
family with sequence similarity 90, member A13
family with sequence similarity 90, member A14
chr8_+_7114425 0.261 NM_001164456
NM_001164452
FAM90A13
FAM90A14
family with sequence similarity 90, member A13
family with sequence similarity 90, member A14
chr10_+_695887 0.257 C10orf108
chromosome 10 open reading frame 108
chr9_+_21440452 0.247 NM_024013
IFNA1
interferon, alpha 1
chr20_-_23731558 0.237 NM_001898
CST1
cystatin SN
chr19_+_39899749 0.236


chr10_-_48806862 0.234 NM_001042357
NM_001042389
PTPN20B
PTPN20A
protein tyrosine phosphatase, non-receptor type 20B
protein tyrosine phosphatase, non-receptor type 20A
chr14_+_85999464 0.234


chr14_-_106610338 0.233 IGHV4-31
IGHG1
immunoglobulin heavy variable 4-31
immunoglobulin heavy constant gamma 1 (G1m marker)
chr7_+_20655244 0.222 NM_001163941
ABCB5
ATP-binding cassette, sub-family B (MDR/TAP), member 5
chr12_+_21525801 0.220 NM_000415
IAPP
islet amyloid polypeptide
chr9_+_131683173 0.219 NM_001100876
NM_174933
PHYHD1

phytanoyl-CoA dioxygenase domain containing 1

chr9_+_27524311 0.215 NM_020124
IFNK
interferon, kappa
chr11_+_63974144 0.207 NM_031471
NM_178443
FERMT3

fermitin family member 3

chr9_+_95736717 0.206 NM_033086
FGD3
FYVE, RhoGEF and PH domain containing 3
chr3_-_190167597 0.203 NM_207316
TMEM207
transmembrane protein 207
chr5_-_150727088 0.197 NM_181776
SLC36A2
solute carrier family 36 (proton/amino acid symporter), member 2
chr3_-_120400957 0.192 HGD
homogentisate 1,2-dioxygenase
chr9_-_124984018 0.187 NM_001242335
LHX6
LIM homeobox 6
chr2_-_231789940 0.178 NM_005683
GPR55
G protein-coupled receptor 55
chr5_-_149792276 0.155 CD74
CD74 molecule, major histocompatibility complex, class II invariant chain
chr15_+_52311408 0.153 NM_002748
MAPK6
mitogen-activated protein kinase 6
chr12_-_91505541 0.146 NM_002345
LUM
lumican
chr4_+_154178525 0.145 TRIM2
tripartite motif containing 2
chr1_-_159684274 0.143 NM_000567
CRP
C-reactive protein, pentraxin-related
chr4_+_159593233 0.135 NM_004453
ETFDH
electron-transferring-flavoprotein dehydrogenase
chr14_-_77542533 0.123


chr5_+_94982480 0.122 NM_001131066
NM_001131065
NM_173362
RFESD


Rieske (Fe-S) domain containing


chr5_-_176937337 0.121 NM_001144875
NM_001144876
DOK3

docking protein 3

chr3_+_46448678 0.103 NM_003965
NM_001130910
CCRL2

chemokine (C-C motif) receptor-like 2

chr9_-_133769224 0.102 NM_198180
QRFP
pyroglutamylated RFamide peptide
chr12_+_51318515 0.098 NM_014033
METTL7A
methyltransferase like 7A
chr15_+_52311432 0.096 MAPK6
mitogen-activated protein kinase 6
chr17_-_48264039 0.060 COL1A1
collagen, type I, alpha 1
chr15_+_59908724 0.057 GCNT3
glucosaminyl (N-acetyl) transferase 3, mucin type
chr15_+_59908908 0.044 GCNT3
glucosaminyl (N-acetyl) transferase 3, mucin type
chr11_+_45115563 0.042 NM_020229
PRDM11
PR domain containing 11
chr1_+_104292278 0.041 NM_001008221
AMY1A
amylase, alpha 1A (salivary)
chr5_-_149324282 0.034 NM_000440
PDE6A
phosphodiesterase 6A, cGMP-specific, rod, alpha
chr13_+_97794050 0.031 MBNL2
muscleblind-like 2 (Drosophila)
chr15_+_85291802 0.028 NM_014630
ZNF592
zinc finger protein 592
chr1_-_104239071 0.021 NM_001008221
AMY1A
amylase, alpha 1A (salivary)
chr4_+_41983712 0.017 NM_001029955
DCAF4L1
DDB1 and CUL4 associated factor 4-like 1
chr11_-_65638672 0.014 EFEMP2
EGF containing fibulin-like extracellular matrix protein 2
chr12_-_53575121 0.003 CSAD
cysteine sulfinic acid decarboxylase
chr3_-_50608421 0.000 NM_001171741
C3orf18
chromosome 3 open reading frame 18

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
10.68 2.85e-06 GO:0006955 immune response
6.54 1.87e-04 GO:0002376 immune system process

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
6.35 8.30e-03 GO:0005624 membrane fraction
6.16 9.88e-03 GO:0005626 insoluble fraction
4.70 4.23e-02 GO:0000267 cell fraction

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
140.77 3.44e-13 GO:0003823 antigen binding